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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77975668
log Bayes Factor = 9.39881
Chromosome 7   position 23,049,393  (GRCh37) Explore rs77975668 on Ensembl!
Variant rs77975668 is part of Cluster X0050

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
H65-H75 Diseases of middle ear and mastoid
0.993 0.007 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.989 0.011 0.000
H40-H42 Glaucoma
0.985 0.015 0.000
Chapter XXI Factors influencing health status and contact with health services
0.985 0.015 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.980 0.020 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.980 0.020 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.977 0.023 0.000
H40 Glaucoma
0.975 0.025 0.000
Z51 Other medical care
0.973 0.027 0.000
H40.9 Glaucoma, unspecified
0.967 0.033 0.000
H52 Disorders of refraction and accommodation
0.963 0.037 0.000
Chapter II Neoplasms
0.962 0.038 0.000
J00-J06 Acute upper respiratory infections
0.961 0.039 0.000
J09-J18 Influenza and pneumonia
0.958 0.042 0.000
S20-S29 Injuries to the thorax
0.954 0.046 0.000
Z51.0 Radiotherapy session
0.951 0.049 0.000
J20-J22 Other acute lower respiratory infections
0.944 0.056 0.000
J90-J94 Other diseases of pleura
0.943 0.057 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.941 0.059 0.000
H65 Nonsuppurative otitis media
0.938 0.062 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.938 0.062 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.938 0.062 0.000
H52.1 Myopia
0.937 0.063 0.000
J03 Acute tonsillitis
0.928 0.072 0.000
Z50 Care involving use of rehabilitation procedures
0.928 0.072 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.924 0.076 0.000
H71 Cholesteatoma of middle ear
0.921 0.079 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.919 0.081 0.000
C15-C26 Malignant neoplasms of digestive organs
0.913 0.087 0.000
C64-C68 Malignant neoplasms of urinary tract
0.910 0.090 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.908 0.092 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.906 0.094 0.000
J22 Unspecified acute lower respiratory infection
0.905 0.095 0.000
J03.9 Acute tonsillitis, unspecified
0.904 0.096 0.000
O60-O75 Complications of labour and delivery
0.900 0.100 0.000
H60-H62 Diseases of external ear
0.896 0.104 0.000
S80-S89 Injuries to the knee and lower leg
0.895 0.105 0.000
O00-O08 Pregnancy with abortive outcome
0.893 0.107 0.000
M80-M85 Disorders of bone density and structure
0.890 0.110 0.000
H30-H36 Disorders of choroid and retina
0.886 0.114 0.000
Z50.1 Other physical therapy
0.885 0.115 0.000
M45-M49 Spondylopathies
0.885 0.115 0.000
M70-M79 Other soft tissue disorders
0.884 0.116 0.000
J40-J47 Chronic lower respiratory diseases
0.883 0.117 0.000
M40-M43 Deforming dorsopathies
0.881 0.119 0.000
Z37 Outcome of delivery
0.881 0.119 0.000
C67 Malignant neoplasm of bladder
0.880 0.120 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.880 0.120 0.000
N18 Chronic renal failure
0.879 0.121 0.000
Chapter XIV Diseases of the genitourinary system
0.879 0.121 0.000
N17-N19 Renal failure
0.877 0.123 0.000
H90-H95 Other disorders of ear
0.874 0.126 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.874 0.126 0.000
Z36 Antenatal screening
0.869 0.131 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.868 0.132 0.000
N18.3 Chronic kidney disease, stage 3
0.865 0.135 0.000
H52.2 Astigmatism
0.864 0.136 0.000
J90 Pleural effusion, not elsewhere classified
0.861 0.139 0.000
M50-M54 Other dorsopathies
0.857 0.143 0.000
S22.4 Multiple fractures of ribs
0.856 0.144 0.000
T92 Sequelae of injuries of upper limb
0.853 0.147 0.000
N18.9 Chronic renal failure, unspecified
0.852 0.148 0.000
S70-S79 Injuries to the hip and thigh
0.850 0.150 0.000
H65.3 Chronic mucoid otitis media
0.847 0.153 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.846 0.154 0.000
Z51.8 Other specified medical care
0.844 0.156 0.000
H66 Suppurative and unspecified otitis media
0.844 0.156 0.000
C25 Malignant neoplasm of pancreas
0.842 0.158 0.000
H49 Paralytic strabismus
0.840 0.160 0.000
H50 Other strabismus
0.839 0.161 0.000
H35 Other retinal disorders
0.839 0.161 0.000
Z51.5 Palliative care
0.836 0.164 0.000
Z37.0 Single live birth
0.830 0.170 0.000
C20 Malignant neoplasm of rectum
0.830 0.170 0.000
M50 Cervical disk disorders
0.830 0.170 0.000
M47 Spondylosis
0.829 0.171 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.828 0.172 0.000
H69 Other disorders of Eustachian tube
0.828 0.172 0.000
H55-H59 Other disorders of eye and adnexa
0.828 0.172 0.000
O04 Medical abortion
0.824 0.176 0.000
J93 Pneumothorax
0.821 0.179 0.000
S22.40 Multiple fractures of ribs (closed)
0.820 0.180 0.000
J60-J70 Lung diseases due to external agents
0.819 0.181 0.000
M47.8 Other spondylosis
0.818 0.182 0.000
M86-M90 Other osteopathies
0.814 0.186 0.000
C67.9 Bladder, unspecified
0.814 0.186 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.812 0.187 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.811 0.189 0.000
D00-D09 In situ neoplasms
0.811 0.189 0.000
O70 Perineal laceration during delivery
0.811 0.189 0.000
Z47 Other orthopaedic follow-up care
0.811 0.189 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.810 0.190 0.000
J11 Influenza, virus not identified
0.809 0.191 0.000
J17 Pneumonia in diseases classified elsewhere
0.806 0.194 0.000
M85 Other disorders of bone density and structure
0.801 0.199 0.000
J95-J99 Other diseases of the respiratory system
0.801 0.199 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.801 0.199 0.000
T90 Sequelae of injuries of head
0.798 0.202 0.000
Z54 Convalescence
0.798 0.202 0.000
S20 Superficial injury of thorax
0.795 0.205 0.000
J40 Bronchitis, not specified as acute or chronic
0.793 0.207 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.793 0.207 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.793 0.207 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.792 0.208 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.790 0.209 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.789 0.211 0.000
H90 Conductive and sensorineural hearing loss
0.788 0.212 0.000
M72 Fibroblastic disorders
0.788 0.212 0.000
S50-S59 Injuries to the elbow and forearm
0.784 0.216 0.000
H40.2 Primary angle-closure glaucoma
0.780 0.220 0.000
J30-J39 Other diseases of upper respiratory tract
0.780 0.220 0.000
T79-T79 Certain early complications of trauma
0.779 0.221 0.000
H60 Otitis externa
0.778 0.222 0.000
M47.82 Other spondylosis (Cervical region)
0.778 0.222 0.000
M77 Other enthesopathies
0.772 0.228 0.000
J04 Acute laryngitis and tracheitis
0.772 0.228 0.000
H34 Retinal vascular occlusions
0.772 0.228 0.000
J18 Pneumonia, organism unspecified
0.772 0.228 0.000
Q60-Q64 Congenital malformations of the urinary system
0.767 0.233 0.000
Z50.2 Alcohol rehabilitation
0.766 0.234 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.766 0.234 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.765 0.235 0.000
H72 Perforation of tympanic membrane
0.765 0.235 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.765 0.235 0.000
T66-T78 Other and unspecified effects of external causes
0.764 0.236 0.000
J00 Acute nasopharyngitis [common cold]
0.762 0.238 0.000
M50.1 Cervical disk disorder with radiculopathy
0.759 0.241 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.759 0.241 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.758 0.242 0.000
H80-H83 Diseases of inner ear
0.758 0.242 0.000
M41 Scoliosis
0.758 0.242 0.000
H40.1 Primary open-angle glaucoma
0.757 0.243 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.757 0.243 0.000
J43 Emphysema
0.756 0.244 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.756 0.244 0.000
S10-S19 Injuries to the neck
0.753 0.247 0.000
H35.8 Other specified retinal disorders
0.752 0.247 0.000
O70.0 First degree perineal laceration during delivery
0.751 0.249 0.000
S83.2 Tear of meniscus, current
0.749 0.251 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.749 0.251 0.000
C25.0 Head of pancreas
0.748 0.252 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.746 0.253 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.746 0.254 0.000
T82.1 Mechanical complication of cardiac electronic device
0.745 0.255 0.000
Z42 Follow-up care involving plastic surgery
0.742 0.258 0.000
H90.2 Conductive hearing loss, unspecified
0.742 0.258 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.742 0.258 0.000
O85-O92 Complications predominantly related to the puerperium
0.742 0.258 0.000
S90-S99 Injuries to the ankle and foot
0.740 0.260 0.000
H61 Other disorders of external ear
0.739 0.261 0.000
S22.0 Fracture of thoracic vertebra
0.738 0.261 0.000
M43 Other deforming dorsopathies
0.738 0.262 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.737 0.263 0.000
H70 Mastoiditis and related conditions
0.737 0.263 0.000
Z41 Procedures for purposes other than remedying health state
0.736 0.264 0.000
M50.3 Other cervical disk degeneration
0.734 0.265 0.000
C21 Malignant neoplasm of anus and anal canal
0.734 0.266 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.732 0.268 0.000
C66 Malignant neoplasm of ureter
0.731 0.269 0.000
H74 Other disorders of middle ear and mastoid
0.731 0.269 0.000
D09 Carcinoma in situ of other and unspecified sites
0.731 0.269 0.000
H35.5 Hereditary retinal dystrophy
0.731 0.269 0.000
H10-H13 Disorders of conjunctiva
0.730 0.270 0.000
M47.86 Other spondylosis (Lumbar region)
0.730 0.270 0.000
Z34 Supervision of normal pregnancy
0.730 0.270 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.730 0.270 0.000
Z51.9 Medical care, unspecified
0.728 0.272 0.000
H46 Optic neuritis
0.728 0.272 0.000
N99-N99 Other disorders of the genitourinary system
0.728 0.272 0.000
M91-M94 Chondropathies
0.727 0.273 0.000
J10 Influenza due to identified influenza virus
0.726 0.274 0.000
M50.2 Other cervical disk displacement
0.725 0.275 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.724 0.276 0.000
C65 Malignant neoplasm of renal pelvis
0.724 0.276 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.723 0.277 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.722 0.278 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.721 0.279 0.000
O04.9 Complete or unspecified, without complication
0.721 0.279 0.000
C16 Malignant neoplasm of stomach
0.720 0.280 0.000
Z50.5 Speech therapy
0.719 0.281 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.719 0.281 0.000
C81 Hodgkin's disease
0.718 0.282 0.000
H65.4 Other chronic nonsuppurative otitis media
0.718 0.282 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.718 0.282 0.000
S86 Injury of muscle and tendon at lower leg level
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
T92.0 Sequelae of open wound of upper limb
0.716 0.284 0.000
O73 Retained placenta and membranes, without haemorrhage
0.715 0.285 0.000
M87 Osteonecrosis
0.714 0.286 0.000
N18.5 Chronic kidney disease, stage 5
0.714 0.286 0.000
H40.8 Other glaucoma
0.714 0.286 0.000
J92 Pleural plaque
0.713 0.287 0.000
J18.9 Pneumonia, unspecified
0.713 0.287 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.712 0.288 0.000
H68 Eustachian salpingitis and obstruction
0.712 0.288 0.000
H67 Otitis media in diseases classified elsewhere
0.712 0.288 0.000
C25.9 Pancreas, unspecified
0.712 0.288 0.000
J93.1 Other spontaneous pneumothorax
0.712 0.288 0.000
C67.4 Posterior wall of bladder
0.712 0.288 0.000
Z40 Prophylactic surgery
0.711 0.289 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.711 0.289 0.000
C88 Malignant immunoproliferative diseases
0.710 0.289 0.000
H69.9 Eustachian tube disorder, unspecified
0.710 0.290 0.000
S27 Injury of other and unspecified intrathoracic organs
0.710 0.290 0.000
H50.5 Heterophoria
0.710 0.290 0.000
H51 Other disorders of binocular movement
0.709 0.291 0.000
S70 Superficial injury of hip and thigh
0.709 0.291 0.000
O80-O84 Delivery
0.708 0.292 0.000
J42 Unspecified chronic bronchitis
0.707 0.293 0.000
H42 Glaucoma in diseases classified elsewhere
0.707 0.293 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.706 0.294 0.000
J02 Acute pharyngitis
0.705 0.295 0.000
S72 Fracture of femur
0.704 0.296 0.000
M84 Disorders of continuity of bone
0.704 0.296 0.000
S89 Other and unspecified injuries of lower leg
0.704 0.296 0.000
H35.6 Retinal haemorrhage
0.703 0.297 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.703 0.297 0.000
J38.3 Other diseases of vocal cords
0.702 0.298 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.702 0.298 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.702 0.298 0.000
T86 Failure and rejection of transplanted organs and tissues
0.702 0.298 0.000
M00-M03 Infectious arthropathies
0.701 0.298 0.000
C17 Malignant neoplasm of small intestine
0.701 0.299 0.000
O72 Postpartum haemorrhage
0.701 0.299 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.700 0.300 0.000
O02 Other abnormal products of conception
0.699 0.300 0.000
H40.6 Glaucoma secondary to drugs
0.699 0.301 0.000
H40.4 Glaucoma secondary to eye inflammation
0.699 0.301 0.000
H40.3 Glaucoma secondary to eye trauma
0.699 0.301 0.000
Z32 Pregnancy examination and test
0.698 0.302 0.000
Z44 Fitting and adjustment of external prosthetic device
0.698 0.302 0.000
Z51.6 Desensitisation to allergens
0.697 0.302 0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.697 0.303 0.000
M71 Other bursopathies
0.694 0.306 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.692 0.308 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.692 0.308 0.000
Z36.9 Antenatal screening, unspecified
0.692 0.308 0.000
H60.9 Otitis externa, unspecified
0.692 0.308 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.691 0.309 0.000
H52.7 Disorder of refraction, unspecified
0.691 0.309 0.000
H52.6 Other disorders of refraction
0.691 0.309 0.000
H52.5 Disorders of accommodation
0.691 0.309 0.000
H52.4 Presbyopia
0.691 0.309 0.000
T92.1 Sequelae of fracture of arm
0.690 0.310 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.690 0.310 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.690 0.310 0.000
Z35 Supervision of high-risk pregnancy
0.690 0.310 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.689 0.310 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.690 0.310 0.000
T98 Sequelae of other and unspecified effects of external causes
0.689 0.311 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.689 0.311 0.000
C85.1 B-cell lymphoma, unspecified
0.689 0.311 0.000
H49.1 Fourth [trochlear] nerve palsy
0.688 0.312 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.688 0.312 0.000
N19 Unspecified renal failure
0.688 0.312 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.688 0.312 0.000
M76 Enthesopathies of lower limb, excluding foot
0.687 0.313 0.000
J14 Pneumonia due to Haemophilus influenzae
0.687 0.313 0.000
Z52 Donors of organs and tissues
0.687 0.313 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.687 0.313 0.000
J12 Viral pneumonia, not elsewhere classified
0.687 0.313 0.000
J09 Influenza due to certain identified influenza virus
0.687 0.313 0.000
H43-H45 Disorders of vitreous body and globe
0.684 0.316 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.684 0.316 0.000
S26 Injury of heart
0.684 0.316 0.000
S25 Injury of blood vessels of thorax
0.684 0.316 0.000
S24 Injury of nerves and spinal cord at thorax level
0.684 0.316 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.684 0.316 0.000
S21 Open wound of thorax
0.684 0.316 0.000
Chapter XXII Codes for special purposes
0.684 0.316 0.000
S22.2 Fracture of sternum
0.684 0.316 0.000
C67.2 Lateral wall of bladder
0.681 0.319 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.681 0.319 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.680 0.319 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.680 0.320 0.000
H57 Other disorders of eye and adnexa
0.680 0.320 0.000
Q80-Q89 Other congenital malformations
0.680 0.320 0.000
C67.3 Anterior wall of bladder
0.680 0.320 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.680 0.320 0.000
M85.0 Fibrous dysplasia (monostotic)
0.679 0.320 0.000
H66.3 Other chronic suppurative otitis media
0.679 0.321 0.000
J21 Acute bronchiolitis
0.677 0.323 0.000
H50.2 Vertical strabismus
0.676 0.324 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.676 0.324 0.000
Z38 Liveborn infants according to place of birth
0.675 0.325 0.000
J20 Acute bronchitis
0.674 0.325 0.000
Z31 Procreative management
0.674 0.326 0.000
D09.0 Bladder
0.674 0.326 0.000
C34 Malignant neoplasm of bronchus and lung
0.673 0.327 0.000
H65.1 Other acute nonsuppurative otitis media
0.673 0.327 0.000
H65.0 Acute serous otitis media
0.673 0.327 0.000
T95 Sequelae of burns, corrosions and frostbite
0.672 0.327 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.672 0.327 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.672 0.327 0.000
H65.2 Chronic serous otitis media
0.672 0.328 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.672 0.328 0.000
J33 Nasal polyp
0.672 0.328 0.000
M82 Osteoporosis in diseases classified elsewhere
0.672 0.328 0.000
Z49 Care involving dialysis
0.671 0.329 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.671 0.329 0.000
H35.0 Background retinopathy and retinal vascular changes
0.671 0.329 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.670 0.330 0.000
Q61 Cystic kidney disease
0.670 0.330 0.000
S50 Superficial injury of forearm
0.670 0.330 0.000
Z46 Fitting and adjustment of other devices
0.669 0.331 0.000
Z54.0 Convalescence following surgery
0.669 0.331 0.000
M41.9 Scoliosis, unspecified
0.669 0.331 0.000
J01 Acute sinusitis
0.669 0.331 0.000
M85.8 Other specified disorders of bone density and structure
0.668 0.332 0.000
Z22 Carrier of infectious disease
0.668 0.332 0.000
Z50.0 Cardiac rehabilitation
0.668 0.332 0.000
M45 Ankylosing spondylitis
0.668 0.332 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.667 0.333 0.000
Z37.2 Twins, both liveborn
0.667 0.333 0.000
J38.7 Other diseases of larynx
0.667 0.333 0.000
J35 Chronic diseases of tonsils and adenoids
0.667 0.333 0.000
T93 Sequelae of injuries of lower limb
0.666 0.334 0.000
Z51.3 Blood transfusion without reported diagnosis
0.666 0.334 0.000
J43.9 Emphysema, unspecified
0.666 0.334 0.000
O04.4 Incomplete, without complication
0.665 0.335 0.000
J03.8 Acute tonsillitis due to other specified organisms
0.665 0.335 0.000
J03.0 Streptococcal tonsillitis
0.665 0.335 0.000
Z50.6 Orthoptic training
0.665 0.335 0.000
Z50.3 Drug rehabilitation
0.665 0.335 0.000
J46 Status asthmaticus
0.664 0.336 0.000
O00 Ectopic pregnancy
0.663 0.337 0.000
H53-H54 Visual disturbances and blindness
0.663 0.337 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.662 0.338 0.000
C95 Leukaemia of unspecified cell type
0.662 0.338 0.000
C94 Other leukaemias of specified cell type
0.662 0.338 0.000
C93 Monocytic leukaemia
0.662 0.338 0.000
C86 Other specified types of T/NK-cell lymphoma
0.662 0.338 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.662 0.338 0.000
N18.8 Other chronic renal failure
0.661 0.339 0.000
N18.0 End-stage renal disease
0.660 0.340 0.000
T90.4 Sequelae of injury of eye and orbit
0.660 0.340 0.000
J44 Other chronic obstructive pulmonary disease
0.659 0.341 0.000
T87 Complications peculiar to reattachment and amputation
0.659 0.341 0.000
J94 Other pleural conditions
0.659 0.341 0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage
0.659 0.341 0.000
H93 Other disorders of ear, not elsewhere classified
0.658 0.342 0.000
S29 Other and unspecified injuries of thorax
0.658 0.342 0.000
T91 Sequelae of injuries of neck and trunk
0.657 0.343 0.000
J38.0 Paralysis of vocal cords and larynx
0.657 0.343 0.000
C67.6 Ureteric orifice
0.657 0.343 0.000
C67.1 Dome of bladder
0.656 0.344 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.655 0.345 0.000
H50.9 Strabismus, unspecified
0.655 0.345 0.000
C23 Malignant neoplasm of gallbladder
0.654 0.345 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.653 0.347 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.652 0.347 0.000
T90.9 Sequelae of unspecified injury of head
0.652 0.347 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.651 0.349 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.651 0.349 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.651 0.349 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.651 0.349 0.000
H52.3 Anisometropia and aniseikonia
0.651 0.349 0.000
M77.9 Enthesopathy, unspecified
0.650 0.350 0.000
C15 Malignant neoplasm of oesophagus
0.650 0.350 0.000
S22.9 Fracture of bony thorax, part unspecified
0.650 0.350 0.000
S22.8 Fracture of other parts of bony thorax
0.650 0.350 0.000
S22.5 Flail chest
0.650 0.350 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.649 0.351 0.000
Z36.8 Other antenatal screening
0.649 0.351 0.000
S22.1 Multiple fractures of thoracic spine
0.648 0.352 0.000
H34.2 Other retinal artery occlusions
0.648 0.352 0.000
S81 Open wound of lower leg
0.647 0.352 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.647 0.353 0.000
M47.1 Other spondylosis with myelopathy
0.646 0.354 0.000
H49.0 Third [oculomotor] nerve palsy
0.646 0.354 0.000
M80 Osteoporosis with pathological fracture
0.646 0.354 0.000
O74 Complications of anaesthesia during labour and delivery
0.645 0.354 0.000
O71 Other obstetric trauma
0.645 0.354 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.645 0.354 0.000
O60 Preterm delivery
0.645 0.354 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.645 0.355 0.000
D60-D64 Aplastic and other anaemias
0.645 0.355 0.000
M65-M68 Disorders of synovium and tendon
0.645 0.355 0.000
N30-N39 Other diseases of urinary system
0.645 0.355 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.644 0.356 0.000
M87.9 Osteonecrosis, unspecified
0.643 0.357 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.643 0.357 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.642 0.357 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.642 0.357 0.000
C67.5 Bladder neck
0.642 0.358 0.000
H81 Disorders of vestibular function
0.642 0.358 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.642 0.358 0.000
N32.9 Bladder disorder, unspecified
0.642 0.358 0.000
S88 Traumatic amputation of lower leg
0.641 0.359 0.000
S87 Crushing injury of lower leg
0.641 0.359 0.000
S85 Injury of blood vessels at lower leg level
0.641 0.359 0.000
S84 Injury of nerves at lower leg level
0.641 0.359 0.000
N00-N08 Glomerular diseases
0.641 0.359 0.000
N60-N64 Disorders of breast
0.641 0.359 0.000
J86 Pyothorax
0.640 0.360 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.640 0.360 0.000
O07 Failed attempted abortion
0.640 0.360 0.000
O06 Unspecified abortion
0.640 0.360 0.000
O05 Other abortion
0.640 0.360 0.000
O01 Hydatidiform mole
0.640 0.360 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.640 0.360 0.000
O66 Other obstructed labour
0.640 0.360 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.640 0.360 0.000
N32 Other disorders of bladder
0.639 0.361 0.000
H40.0 Glaucoma suspect
0.638 0.362 0.000
M83 Adult osteomalacia
0.638 0.362 0.000
C91 Lymphoid leukaemia
0.637 0.363 0.000
J04.1 Acute tracheitis
0.637 0.363 0.000
J93.9 Pneumothorax, unspecified
0.636 0.364 0.000
O70.9 Perineal laceration during delivery, unspecified
0.636 0.364 0.000
S82 Fracture of lower leg, including ankle
0.635 0.365 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.635 0.365 0.000
H31 Other disorders of choroid
0.635 0.365 0.000
H30 Chorioretinal inflammation
0.635 0.365 0.000
H49.2 Sixth [abducent] nerve palsy
0.635 0.365 0.000
H92 Otalgia and effusion of ear
0.635 0.365 0.000
M49 Spondylopathies in diseases classified elsewhere
0.634 0.366 0.000
O20 Haemorrhage in early pregnancy
0.634 0.366 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.634 0.366 0.000
J41 Simple and mucopurulent chronic bronchitis
0.633 0.367 0.000
H35.9 Retinal disorder, unspecified
0.633 0.367 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.632 0.368 0.000
M42 Spinal osteochondrosis
0.632 0.368 0.000
M40 Kyphosis and lordosis
0.632 0.368 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.632 0.368 0.000
Z37.9 Outcome of delivery unspecified
0.631 0.368 0.000
Z37.7 Other multiple births, all stillborn
0.631 0.368 0.000
Z37.6 Other multiple births, some liveborn
0.631 0.368 0.000
Z37.5 Other multiple births, all liveborn
0.631 0.368 0.000
Z37.4 Twins, both stillborn
0.631 0.368 0.000
Z37.3 Twins, one liveborn and one stillborn
0.631 0.368 0.000
Z37.1 Single stillbirth
0.631 0.368 0.000
Q00-Q07 Congenital malformations of the nervous system
0.631 0.369 0.000
C67.8 Overlapping lesion of bladder
0.631 0.369 0.000
C67.7 Urachus
0.631 0.369 0.000
C67.0 Trigone of bladder
0.631 0.369 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.631 0.369 0.000
Q35-Q37 Cleft lip and cleft palate
0.631 0.369 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.631 0.369 0.000
N18.1 Chronic kidney disease, stage 1
0.631 0.369 0.000
M46 Other inflammatory spondylopathies
0.630 0.369 0.000
Z39 Postpartum care and examination
0.629 0.371 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.629 0.371 0.000
Chapter XX External causes of morbidity and mortality
0.629 0.371 0.000
H34.8 Other retinal vascular occlusions
0.628 0.372 0.000
D05 Carcinoma in situ of breast
0.628 0.372 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.627 0.373 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.627 0.373 0.000
C85.0 Lymphosarcoma
0.627 0.373 0.000
N18.2 Chronic kidney disease, stage 2
0.625 0.374 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.625 0.375 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.625 0.375 0.000
M89 Other disorders of bone
0.625 0.375 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.625 0.375 0.000
Q50-Q56 Congenital malformations of genital organs
0.624 0.375 0.000
J91 Pleural effusion in conditions classified elsewhere
0.624 0.375 0.000
C83.0 Small cell (diffuse)
0.624 0.375 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.624 0.376 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.623 0.377 0.000
Z36.5 Antenatal screening for isoimmunisation
0.623 0.377 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.623 0.377 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.623 0.377 0.000
N76 Other inflammation of vagina and vulva
0.622 0.378 0.000
J35.0 Chronic tonsillitis
0.622 0.378 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.621 0.379 0.000
Z33 Pregnant state, incidental
0.621 0.379 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.621 0.379 0.000
S31 Open wound of abdomen, lower back and pelvis
0.620 0.380 0.000
C50-C50 Malignant neoplasm of breast
0.619 0.381 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.619 0.381 0.000
H35.4 Peripheral retinal degeneration
0.619 0.381 0.000
H50.0 Convergent concomitant strabismus
0.618 0.381 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.618 0.381 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.618 0.382 0.000
O61 Failed induction of labour
0.618 0.382 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.618 0.382 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.617 0.383 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.617 0.383 0.000
H25-H28 Disorders of lens
0.617 0.383 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.616 0.383 0.000
M77.1 Lateral epicondylitis
0.616 0.384 0.000
M43.1 Spondylolisthesis
0.616 0.384 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.614 0.386 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.614 0.386 0.000
S22.41 Multiple fractures of ribs (open)
0.614 0.386 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.613 0.387 0.000
Z48 Other surgical follow-up care
0.613 0.387 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.613 0.387 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.612 0.388 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.612 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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