TreeWAS – Variant ID: rs78034869

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000
Chapter IX Diseases of the circulatory system	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002
D10-D36 Benign neoplasms	0.997	0.003
I30-I52 Other forms of heart disease	0.997	0.003
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.994	0.006
D23 Other benign neoplasms of skin	0.986	0.014
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.986	0.014
Chapter XIV Diseases of the genitourinary system	0.979	0.021
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.975	0.025
M45-M49 Spondylopathies	0.975	0.025
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.972	0.028
Chapter X Diseases of the respiratory system	0.969	0.031
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.961	0.039
Chapter XXI Factors influencing health status and contact with health services	0.953	0.047
H25-H28 Disorders of lens	0.951	0.049
N17-N19 Renal failure	0.951	0.049
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.949	0.051
M47 Spondylosis	0.940	0.060
I44 Atrioventricular and left bundle-branch block	0.940	0.060
H55-H59 Other disorders of eye and adnexa	0.937	0.063
N00-N08 Glomerular diseases	0.937	0.063
J80-J84 Other respiratory diseases principally affecting the interstitium	0.937	0.063
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.935	0.065
D12.6 Colon, unspecified	0.934	0.066
H26 Other cataract	0.933	0.067
R03 Abnormal blood-pressure reading, without diagnosis	0.931	0.069
D17 Benign lipomatous neoplasm	0.926	0.074
H26.9 Cataract, unspecified	0.924	0.076
Chapter I Certain infectious and parasitic diseases	0.924	0.076
C15-C26 Malignant neoplasms of digestive organs	0.923	0.077
R23 Other skin changes	0.922	0.078
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.921	0.079
R07 Pain in throat and chest	0.920	0.080
S80-S89 Injuries to the knee and lower leg	0.920	0.080
R06 Abnormalities of breathing	0.919	0.081
D23.5 Skin of trunk	0.915	0.085
R04 Haemorrhage from respiratory passages	0.915	0.085
J09-J18 Influenza and pneumonia	0.914	0.086
Chapter IV Endocrine, nutritional and metabolic diseases	0.911	0.089
Z00-Z13 Persons encountering health services for examination and investigation	0.910	0.090
I45 Other conduction disorders	0.907	0.093
M45 Ankylosing spondylitis	0.905	0.095
I42 Cardiomyopathy	0.903	0.097
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.902	0.098
I44.7 Left bundle-branch block, unspecified	0.900	0.100
D12.3 Transverse colon	0.896	0.104
I31 Other diseases of pericardium	0.895	0.105
J81 Pulmonary oedema	0.895	0.105
H00 Hordeolum and chalazion	0.891	0.109
I70-I79 Diseases of arteries, arterioles and capillaries	0.888	0.112
I10-I15 Hypertensive diseases	0.886	0.114
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.884	0.116
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.883	0.117
C20 Malignant neoplasm of rectum	0.878	0.122
R04.2 Haemoptysis	0.876	0.124
I46 Cardiac arrest	0.872	0.128
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.870	0.130
R07.4 Chest pain, unspecified	0.869	0.131
T66-T78 Other and unspecified effects of external causes	0.869	0.131
T90 Sequelae of injuries of head	0.868	0.132
A30-A49 Other bacterial diseases	0.867	0.133
N70-N77 Inflammatory diseases of female pelvic organs	0.864	0.136
R23.8 Other and unspecified skin changes	0.863	0.137
I47 Paroxysmal tachycardia	0.862	0.138
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.861	0.139
M47.8 Other spondylosis	0.861	0.139
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.858	0.142
D12.0 Caecum	0.858	0.142
M05-M14 Inflammatory polyarthropathies	0.856	0.144
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.856	0.144
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.855	0.145
Z88.6 Personal history of allergy to analgesic agent	0.854	0.146
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.850	0.150
M47.9 Spondylosis, unspecified	0.849	0.151
N19 Unspecified renal failure	0.846	0.154
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.846	0.154
N17 Acute renal failure	0.845	0.155
I95-I99 Other and unspecified disorders of the circulatory system	0.845	0.155
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.842	0.158
I12 Hypertensive renal disease	0.841	0.159
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.840	0.160
N10-N16 Renal tubulo-interstitial diseases	0.840	0.160
D23.1 Skin of eyelid, including canthus	0.839	0.161
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.838	0.162
N03 Chronic nephritic syndrome	0.837	0.163
D23.4 Skin of scalp and neck	0.837	0.163
I49 Other cardiac arrhythmias	0.836	0.164
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.834	0.166
R07.0 Pain in throat	0.833	0.167
C34 Malignant neoplasm of bronchus and lung	0.832	0.168
E10-E14 Diabetes mellitus	0.832	0.168
Chapter XX External causes of morbidity and mortality	0.832	0.168
H18 Other disorders of cornea	0.831	0.169
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.831	0.169
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.831	0.169
M20-M25 Other joint disorders	0.830	0.170
R50-R69 General symptoms and signs	0.829	0.171
H57 Other disorders of eye and adnexa	0.829	0.171
R11 Nausea and vomiting	0.827	0.173
T93 Sequelae of injuries of lower limb	0.827	0.173
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.826	0.174
Z13 Special screening examination for other diseases and disorders	0.825	0.175
J90-J94 Other diseases of pleura	0.820	0.180
N02 Recurrent and persistent haematuria	0.820	0.180
S82 Fracture of lower leg, including ankle	0.818	0.182
N18 Chronic renal failure	0.818	0.182
H30-H36 Disorders of choroid and retina	0.818	0.182
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.817	0.183
H46-H48 Disorders of optic nerve and visual pathways	0.816	0.184
I45.1 Other and unspecified right bundle-branch block	0.816	0.184
J18 Pneumonia, organism unspecified	0.815	0.185
M47.86 Other spondylosis (Lumbar region)	0.814	0.186
H00.1 Chalazion	0.810	0.190
D23.0 Skin of lip	0.808	0.192
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.807	0.193
I12.0 Hypertensive renal disease with renal failure	0.805	0.195
Z98 Other postsurgical states	0.805	0.195
R06.5 Mouth breathing	0.805	0.195
S70-S79 Injuries to the hip and thigh	0.804	0.196
D23.9 Skin, unspecified	0.803	0.197
R20 Disturbances of skin sensation	0.803	0.197
N75 Diseases of Bartholin's gland	0.801	0.199
T92 Sequelae of injuries of upper limb	0.801	0.199
M45.X9 Ankylosing spondylitis (Site unspecified)	0.800	0.200
R03.1 Nonspecific low blood-pressure reading	0.799	0.201
D36 Benign neoplasm of other and unspecified sites	0.799	0.201
T36-T50 Poisoning by drugs, medicaments and biological substances	0.799	0.201
I42.0 Dilated cardiomyopathy	0.798	0.202
M25 Other joint disorders, not elsewhere classified	0.797	0.203
M46 Other inflammatory spondylopathies	0.795	0.205
Z83 Family history of other specific disorders	0.795	0.205
R17 Unspecified jaundice	0.794	0.206
A49 Bacterial infection of unspecified site	0.793	0.207
Z86 Personal history of certain other diseases	0.792	0.208
H00.0 Hordeolum and other deep inflammation of eyelid	0.792	0.208
T79-T79 Certain early complications of trauma	0.791	0.208
I47.2 Ventricular tachycardia	0.791	0.209
R09.1 Pleurisy	0.791	0.209
T15-T19 Effects of foreign body entering through natural orifice	0.790	0.210
R06.8 Other and unspecified abnormalities of breathing	0.790	0.210
H43-H45 Disorders of vitreous body and globe	0.788	0.212
Z13.6 Special screening examination for cardiovascular disorders	0.787	0.213
Z01.8 Other specified special examinations	0.787	0.213
J84 Other interstitial pulmonary diseases	0.786	0.214
I46.0 Cardiac arrest with successful resuscitation	0.784	0.216
D22 Melanocytic naevi	0.784	0.216
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.783	0.217
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.782	0.218
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.781	0.219
J18.9 Pneumonia, unspecified	0.781	0.219
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.780	0.220
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.778	0.222
J95-J99 Other diseases of the respiratory system	0.776	0.224
T78 Adverse effects, not elsewhere classified	0.776	0.224
H16 Keratitis	0.776	0.224
E70-E90 Metabolic disorders	0.775	0.225
C78.2 Secondary malignant neoplasm of pleura	0.774	0.226
J15 Bacterial pneumonia, not elsewhere classified	0.774	0.226
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.774	0.226
N99-N99 Other disorders of the genitourinary system	0.774	0.226
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.773	0.227
S20-S29 Injuries to the thorax	0.772	0.228
N17.9 Acute renal failure, unspecified	0.770	0.230
N18.9 Chronic renal failure, unspecified	0.769	0.231
N76 Other inflammation of vagina and vulva	0.768	0.232
C90 Multiple myeloma and malignant plasma cell neoplasms	0.767	0.233
D00-D09 In situ neoplasms	0.767	0.233
Z98.0 Intestinal bypass and anastomosis status	0.766	0.234
N03.9 Unspecified	0.766	0.234
I37 Pulmonary valve disorders	0.766	0.234
H20 Iridocyclitis	0.765	0.235
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.765	0.235
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.764	0.236
D10 Benign neoplasm of mouth and pharynx	0.763	0.236
I31.9 Disease of pericardium, unspecified	0.763	0.237
H21 Other disorders of iris and ciliary body	0.762	0.238
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.760	0.240
H55 Nystagmus and other irregular eye movements	0.759	0.241
Z86.1 Personal history of infectious and parasitic diseases	0.759	0.241
S00-S09 Injuries to the head	0.759	0.241
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.758	0.241
R47-R49 Symptoms and signs involving speech and voice	0.756	0.243
Z09.0 Follow-up examination after surgery for other conditions	0.756	0.244
I31.3 Pericardial effusion (noninflammatory)	0.755	0.245
D23.7 Skin of lower limb, including hip	0.754	0.246
Z88.1 Personal history of allergy to other antibiotic agents	0.754	0.246
I42.9 Cardiomyopathy, unspecified	0.754	0.246
M60-M63 Disorders of muscles	0.753	0.247
C34.1 Upper lobe, bronchus or lung	0.753	0.247
M47.92 Spondylosis, unspecified (Cervical region)	0.753	0.247
M40-M43 Deforming dorsopathies	0.752	0.248
H10-H13 Disorders of conjunctiva	0.752	0.248
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.750	0.250
S90-S99 Injuries to the ankle and foot	0.750	0.250
C83 Diffuse non-Hodgkin's lymphoma	0.749	0.251
I50 Heart failure	0.749	0.251
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.748	0.252
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.748	0.252
Z93 Artificial opening status	0.748	0.252
S10-S19 Injuries to the neck	0.747	0.253
D26 Other benign neoplasms of uterus	0.747	0.253
S82.5 Fracture of medial malleolus	0.746	0.254
N05 Unspecified nephritic syndrome	0.746	0.254
Z88.5 Personal history of allergy to narcotic agent	0.746	0.254
R18 Ascites	0.745	0.255
Z63 Other problems related to primary support group, including family circumstances	0.745	0.255
E10 Insulin-dependent diabetes mellitus	0.744	0.256
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.744	0.256
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.743	0.257
E89.0 Postprocedural hypothyroidism	0.742	0.258
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.741	0.258
Z70-Z76 Persons encountering health services in other circumstances	0.740	0.260
C51-C58 Malignant neoplasms of female genital organs	0.740	0.260
Q60-Q64 Congenital malformations of the urinary system	0.739	0.261
N60-N64 Disorders of breast	0.738	0.262
N02.9 Unspecified	0.735	0.264
J00-J06 Acute upper respiratory infections	0.735	0.265
R07.1 Chest pain on breathing	0.733	0.267
I33 Acute and subacute endocarditis	0.733	0.267
E20-E35 Disorders of other endocrine glands	0.732	0.268
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.730	0.270
H57.8 Other specified disorders of eye and adnexa	0.730	0.270
H04 Disorders of lachrymal system	0.730	0.270
D12.7 Rectosigmoid junction	0.729	0.271
J93 Pneumothorax	0.729	0.271
R42 Dizziness and giddiness	0.729	0.271
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.728	0.272
R50 Fever of unknown origin	0.726	0.274
N75.0 Cyst of Bartholin's gland	0.726	0.274
D35 Benign neoplasm of other and unspecified endocrine glands	0.726	0.274
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.725	0.275
I70 Atherosclerosis	0.725	0.275
R55 Syncope and collapse	0.724	0.276
M86-M90 Other osteopathies	0.724	0.276
I44.3 Other and unspecified atrioventricular block	0.722	0.278
T93.1 Sequelae of fracture of femur	0.721	0.279
R44 Other symptoms and signs involving general sensations and perceptions	0.720	0.280
R23.2 Flushing	0.720	0.280
I72 Other aneurysm	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
I00-I02 Acute rheumatic fever	0.716	0.284
I20-I25 Ischaemic heart diseases	0.716	0.284
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
T20-T25 Burns and corrosions of external body surface, specified by site	0.715	0.285
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.715	0.285
T00-T07 Injuries involving multiple body regions	0.715	0.285
D31 Benign neoplasm of eye and adnexa	0.715	0.285
D30 Benign neoplasm of urinary organs	0.715	0.285
D29 Benign neoplasm of male genital organs	0.715	0.285
D28 Benign neoplasm of other and unspecified female genital organs	0.715	0.285
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.715	0.285
D19 Benign neoplasm of mesothelial tissue	0.715	0.285
D16 Benign neoplasm of bone and articular cartilage	0.715	0.285
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.715	0.285
D14 Benign neoplasm of middle ear and respiratory system	0.715	0.285
I52 Other heart disorders in diseases classified elsewhere	0.715	0.285
I48 Atrial fibrillation and flutter	0.715	0.285
I43 Cardiomyopathy in diseases classified elsewhere	0.715	0.285
I41 Myocarditis in diseases classified elsewhere	0.715	0.285
I40 Acute myocarditis	0.715	0.285
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.715	0.285
I36 Nonrheumatic tricuspid valve disorders	0.715	0.285
I32 Pericarditis in diseases classified elsewhere	0.715	0.285
D23.3 Skin of other and unspecified parts of face	0.714	0.286
M47.1 Other spondylosis with myelopathy	0.714	0.286
M06 Other rheumatoid arthritis	0.713	0.287
I95 Hypotension	0.713	0.287
D11 Benign neoplasm of major salivary glands	0.713	0.287
S86 Injury of muscle and tendon at lower leg level	0.712	0.288
T90.9 Sequelae of unspecified injury of head	0.711	0.289
Z02 Examination and encounter for administrative purposes	0.711	0.289
R20.2 Paraesthesia of skin	0.711	0.289
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.710	0.290
C73 Malignant neoplasm of thyroid gland	0.710	0.290
Z89 Acquired absence of limb	0.708	0.292
T90.2 Sequelae of fracture of skull and facial bones	0.708	0.292
M05 Seropositive rheumatoid arthritis	0.708	0.292
J84.1 Other interstitial pulmonary diseases with fibrosis	0.708	0.292
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.707	0.293
D23.2 Skin of ear and external auricular canal	0.707	0.293
M91-M94 Chondropathies	0.707	0.293
M00-M03 Infectious arthropathies	0.707	0.293
Z86.0 Personal history of other neoplasms	0.706	0.294
I45.5 Other specified heart block	0.706	0.294
R27 Other lack of coordination	0.705	0.295
C78.0 Secondary malignant neoplasm of lung	0.705	0.295
H27 Other disorders of lens	0.704	0.296
S82.2 Fracture of shaft of tibia	0.703	0.297
I44.1 Atrioventricular block, second degree	0.703	0.297
Z83.3 Family history of diabetes mellitus	0.703	0.297
R23.3 Spontaneous ecchymoses	0.702	0.297
H18.5 Hereditary corneal dystrophies	0.701	0.299
I30 Acute pericarditis	0.701	0.299
Z96 Presence of other functional implants	0.700	0.300
J13 Pneumonia due to Streptococcus pneumoniae	0.699	0.300
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.699	0.301
M25.7 Osteophyte	0.699	0.301
H05 Disorders of orbit	0.699	0.301
M80-M85 Disorders of bone density and structure	0.699	0.301
M49 Spondylopathies in diseases classified elsewhere	0.699	0.301
D12.9 Anus and anal canal	0.697	0.303
D12.1 Appendix	0.697	0.303
I45.9 Conduction disorder, unspecified	0.696	0.304
R06.6 Hiccough	0.696	0.304
D34 Benign neoplasm of thyroid gland	0.696	0.304
D21 Other benign neoplasms of connective and other soft tissue	0.695	0.304
B35-B49 Mycoses	0.695	0.305
T78.4 Allergy, unspecified	0.695	0.305
I71 Aortic aneurysm and dissection	0.695	0.305
S82.50 Fracture of medial malleolus (closed)	0.695	0.305
R22.2 Localised swelling, mass and lump, trunk	0.694	0.306
C19 Malignant neoplasm of rectosigmoid junction	0.694	0.306
R21 Rash and other nonspecific skin eruption	0.694	0.306
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.693	0.307
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.691	0.308
Z01.5 Diagnostic skin and sensitisation tests	0.691	0.309
A49.0 Staphylococcal infection, unspecified	0.691	0.309
R61 Hyperhidrosis	0.690	0.310
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.689	0.311
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.689	0.311
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.689	0.311
T98 Sequelae of other and unspecified effects of external causes	0.689	0.311
T95 Sequelae of burns, corrosions and frostbite	0.689	0.311
T94 Sequelae of injuries involving multiple and unspecified body regions	0.689	0.311
T91 Sequelae of injuries of neck and trunk	0.689	0.311
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.689	0.311
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.689	0.311
I50.0 Congestive heart failure	0.689	0.311
A48 Other bacterial diseases, not elsewhere classified	0.688	0.312
N10 Acute tubulo-interstitial nephritis	0.688	0.312
N08 Glomerular disorders in diseases classified elsewhere	0.685	0.314
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.685	0.315
H46 Optic neuritis	0.685	0.315
B25-B34 Other viral diseases	0.685	0.315
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.683	0.317
J11 Influenza, virus not identified	0.683	0.317
A41 Other septicaemia	0.682	0.317
R22.1 Localised swelling, mass and lump, neck	0.682	0.318
D70-D77 Other diseases of blood and blood-forming organs	0.682	0.318
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.682	0.318
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.682	0.318
R22.9 Localised swelling, mass and lump, unspecified	0.682	0.318
Chapter XXII Codes for special purposes	0.681	0.319
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.680	0.319
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.680	0.319
H17 Corneal scars and opacities	0.680	0.319
H15 Disorders of sclera	0.680	0.319
N76.0 Acute vaginitis	0.680	0.320
M47.82 Other spondylosis (Cervical region)	0.680	0.320
M25.5 Pain in joint	0.680	0.320
H18.4 Corneal degeneration	0.680	0.320
T90.5 Sequelae of intracranial injury	0.679	0.321
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.679	0.321
S40-S49 Injuries to the shoulder and upper arm	0.678	0.322
J80 Adult respiratory distress syndrome	0.678	0.322
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.678	0.322
R25 Abnormal involuntary movements	0.676	0.324
D17.7 Benign lipomatous neoplasm of other sites	0.674	0.326
M47.0 Anterior spinal and vertebral artery compression syndromes	0.674	0.326
I44.6 Other and unspecified fascicular block	0.674	0.326
I44.5 Left posterior fascicular block	0.674	0.326
I44.4 Left anterior fascicular block	0.674	0.326
M24 Other specific joint derangements	0.674	0.326
H34 Retinal vascular occlusions	0.674	0.326
D12.4 Descending colon	0.673	0.327
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.673	0.327
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.672	0.328
N07 Hereditary nephropathy, not elsewhere classified	0.672	0.328
N06 Isolated proteinuria with specified morphological lesion	0.672	0.328
N04 Nephrotic syndrome	0.672	0.328
N01 Rapidly progressive nephritic syndrome	0.672	0.328
N00 Acute nephritic syndrome	0.672	0.328
T85 Complications of other internal prosthetic devices, implants and grafts	0.672	0.328
J82 Pulmonary eosinophilia, not elsewhere classified	0.672	0.328
M70-M79 Other soft tissue disorders	0.672	0.328
H57.9 Disorder of eye and adnexa, unspecified	0.671	0.328
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.671	0.329
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.671	0.329
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.670	0.329
H03 Disorders of eyelid in diseases classified elsewhere	0.670	0.329
Z88.3 Personal history of allergy to other anti-infective agents	0.670	0.330
R52 Pain, not elsewhere classified	0.670	0.330
C92 Myeloid leukaemia	0.669	0.330
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.669	0.331
H35 Other retinal disorders	0.669	0.331
R57 Shock, not elsewhere classified	0.669	0.331
H26.3 Drug-induced cataract	0.669	0.331
H26.2 Complicated cataract	0.669	0.331
H26.1 Traumatic cataract	0.669	0.331
H26.0 Infantile, juvenile and presenile cataract	0.669	0.331
R53 Malaise and fatigue	0.668	0.332
I49.3 Ventricular premature depolarisation	0.667	0.333
M46.9 Inflammatory spondylopathy, unspecified	0.666	0.333
E10.9 Without complications	0.666	0.334
Z60 Problems related to social environment	0.664	0.335
N75.1 Abscess of Bartholin's gland	0.664	0.336
N25-N29 Other disorders of kidney and ureter	0.664	0.336
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.664	0.336
Y86 Sequelae of other accidents	0.664	0.336
B15-B19 Viral hepatitis	0.664	0.336
I78 Diseases of capillaries	0.663	0.337
I44.2 Atrioventricular block, complete	0.663	0.337
R06.0 Dyspnoea	0.663	0.337
T17 Foreign body in respiratory tract	0.663	0.337
B99-B99 Other infectious diseases	0.662	0.338
B90-B94 Sequelae of infectious and parasitic diseases	0.662	0.338
B85-B89 Pediculosis, acariasis and other infestations	0.662	0.338
B65-B83 Helminthiases	0.662	0.338
B50-B64 Protozoal diseases	0.662	0.338
B20-B24 Human immunodeficiency virus [HIV] disease	0.662	0.338
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.662	0.338
A75-A79 Rickettsioses	0.662	0.338
A70-A74 Other diseases caused by chlamydiae	0.662	0.338
A65-A69 Other spirochaetal diseases	0.662	0.338
A50-A64 Infections with a predominantly sexual mode of transmission	0.662	0.338
A20-A28 Certain zoonotic bacterial diseases	0.662	0.338
A15-A19 Tuberculosis	0.662	0.338
C26 Malignant neoplasm of other and ill-defined digestive organs	0.662	0.338
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.662	0.338
C21 Malignant neoplasm of anus and anal canal	0.662	0.338
C17 Malignant neoplasm of small intestine	0.662	0.338
C23 Malignant neoplasm of gallbladder	0.662	0.338
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.662	0.338
R23.4 Changes in skin texture	0.661	0.339
R23.1 Pallor	0.661	0.339
R23.0 Cyanosis	0.661	0.339
T90.4 Sequelae of injury of eye and orbit	0.661	0.339
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.660	0.340
C95 Leukaemia of unspecified cell type	0.660	0.340
C94 Other leukaemias of specified cell type	0.660	0.340
C93 Monocytic leukaemia	0.660	0.340
C88 Malignant immunoproliferative diseases	0.660	0.340
C86 Other specified types of T/NK-cell lymphoma	0.660	0.340
C84 Peripheral and cutaneous T-cell lymphomas	0.660	0.340
C81 Hodgkin's disease	0.660	0.340
E11 Non-insulin-dependent diabetes mellitus	0.660	0.340
S72 Fracture of femur	0.660	0.340
H36 Retinal disorders in diseases classified elsewhere	0.660	0.340
S89 Other and unspecified injuries of lower leg	0.660	0.340
S88 Traumatic amputation of lower leg	0.660	0.340
S87 Crushing injury of lower leg	0.660	0.340
S85 Injury of blood vessels at lower leg level	0.660	0.340
S84 Injury of nerves at lower leg level	0.660	0.340
S81 Open wound of lower leg	0.660	0.340
D33 Benign neoplasm of brain and other parts of central nervous system	0.659	0.340
R06.7 Sneezing	0.659	0.341
R06.3 Periodic breathing	0.659	0.341
R06.2 Wheezing	0.659	0.341
R06.1 Stridor	0.659	0.341
R50.9 Fever, unspecified	0.657	0.343
C90.0 Multiple myeloma	0.657	0.343
Z96.8 Presence of other specified functional implants	0.656	0.344
R04.9 Haemorrhage from respiratory passages, unspecified	0.656	0.344
R04.8 Haemorrhage from other sites in respiratory passages	0.656	0.344
R04.1 Haemorrhage from throat	0.656	0.344
M07 Psoriatic and enteropathic arthropathies	0.656	0.344
A49.9 Bacterial infection, unspecified	0.656	0.344
J17 Pneumonia in diseases classified elsewhere	0.655	0.345
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.655	0.345
J12 Viral pneumonia, not elsewhere classified	0.655	0.345
J10 Influenza due to identified influenza virus	0.655	0.345
J14 Pneumonia due to Haemophilus influenzae	0.655	0.345
J09 Influenza due to certain identified influenza virus	0.655	0.345
A80-A89 Viral infections of the central nervous system	0.655	0.345
H02 Other disorders of eyelid	0.655	0.345
H59.8 Other postprocedural disorders of eye and adnexa	0.655	0.345
J18.0 Bronchopneumonia, unspecified	0.655	0.345
Z83.5 Family history of eye and ear disorders	0.655	0.345
S02 Fracture of skull and facial bones	0.654	0.345
N13 Obstructive and reflux uropathy	0.654	0.346
A00-A09 Intestinal infectious diseases	0.653	0.347
N60 Benign mammary dysplasia	0.653	0.347
H26.4 After-cataract	0.653	0.347
M47.2 Other spondylosis with radiculopathy	0.653	0.347
I42.1 Obstructive hypertrophic cardiomyopathy	0.653	0.347
E40-E46 Malnutrition	0.653	0.347
R56 Convulsions, not elsewhere classified	0.653	0.347
Z10 Routine general health check-up of defined subpopulation	0.652	0.347
M47.87 Other spondylosis (Lumbosacral region)	0.652	0.348
I77 Other disorders of arteries and arterioles	0.652	0.348
H16.9 Keratitis, unspecified	0.652	0.348
C34.9 Bronchus or lung, unspecified	0.652	0.348
I49.9 Cardiac arrhythmia, unspecified	0.652	0.348
I82 Other venous embolism and thrombosis	0.651	0.349
I45.8 Other specified conduction disorders	0.650	0.350
I45.4 Nonspecific intraventricular block	0.650	0.350
I45.3 Trifascicular block	0.650	0.350
I45.2 Bifascicular block	0.650	0.350
I45.0 Right fascicular block	0.650	0.350
Q00-Q07 Congenital malformations of the nervous system	0.650	0.350
Q38-Q45 Other congenital malformations of the digestive system	0.650	0.350
M25.6 Stiffness of joint, not elsewhere classified	0.649	0.351

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations