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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78156933
log Bayes Factor = 6.63681
Chromosome 4   position 27,656,295  (GRCh37) Explore rs78156933 on Ensembl!
Variant rs78156933 is part of Cluster X0084

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
B95-B98 Bacterial, viral and other infectious agents
0.996 0.004 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.994 0.006 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.993 0.007 0.000
N20-N23 Urolithiasis
0.993 0.007 0.000
N20 Calculus of kidney and ureter
0.991 0.009 0.000
M35 Other systemic involvement of connective tissue
0.984 0.016 0.000
N20.0 Calculus of kidney
0.974 0.026 0.000
Chapter IX Diseases of the circulatory system
0.969 0.031 0.000
Chapter VIII Diseases of the ear and mastoid process
0.968 0.032 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.967 0.033 0.000
M35.3 Polymyalgia rheumatica
0.963 0.037 0.000
I30-I52 Other forms of heart disease
0.961 0.039 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.959 0.041 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.959 0.041 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.958 0.042 0.000
N00-N08 Glomerular diseases
0.954 0.046 0.000
M24 Other specific joint derangements
0.954 0.046 0.000
N60-N64 Disorders of breast
0.951 0.049 0.000
N73 Other female pelvic inflammatory diseases
0.950 0.050 0.000
N73.6 Female pelvic peritoneal adhesions
0.944 0.056 0.000
Chapter V Mental and behavioural disorders
0.944 0.056 0.000
M45-M49 Spondylopathies
0.944 0.056 0.000
I44 Atrioventricular and left bundle-branch block
0.937 0.063 0.000
S00-S09 Injuries to the head
0.933 0.067 0.000
Y95 Nosocomial condition
0.932 0.068 0.000
N62 Hypertrophy of breast
0.911 0.089 0.000
H90-H95 Other disorders of ear
0.910 0.090 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.908 0.092 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.904 0.096 0.000
M25 Other joint disorders, not elsewhere classified
0.903 0.097 0.000
I45 Other conduction disorders
0.903 0.097 0.000
I44.0 Atrioventricular block, first degree
0.901 0.099 0.000
M22 Disorders of patella
0.895 0.105 0.000
M48 Other spondylopathies
0.893 0.107 0.000
N20.2 Calculus of kidney with calculus of ureter
0.891 0.109 0.000
I45.1 Other and unspecified right bundle-branch block
0.883 0.117 0.000
N20.1 Calculus of ureter
0.882 0.118 0.000
H90 Conductive and sensorineural hearing loss
0.876 0.124 0.000
I47 Paroxysmal tachycardia
0.875 0.124 0.000
F30-F39 Mood [affective] disorders
0.874 0.126 0.000
S01 Open wound of head
0.874 0.126 0.000
I44.2 Atrioventricular block, complete
0.873 0.127 0.000
N61 Inflammatory disorders of breast
0.870 0.130 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.865 0.135 0.000
M24.1 Other articular cartilage disorders
0.862 0.138 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.860 0.140 0.000
A00-A09 Intestinal infectious diseases
0.859 0.141 0.000
N02 Recurrent and persistent haematuria
0.852 0.148 0.000
M40-M43 Deforming dorsopathies
0.849 0.151 0.000
M48.0 Spinal stenosis
0.848 0.152 0.000
M86-M90 Other osteopathies
0.847 0.153 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.846 0.154 0.000
N05 Unspecified nephritic syndrome
0.843 0.157 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.842 0.158 0.000
S40-S49 Injuries to the shoulder and upper arm
0.839 0.161 0.000
M25.7 Osteophyte
0.839 0.161 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.836 0.164 0.000
S50-S59 Injuries to the elbow and forearm
0.834 0.166 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.832 0.168 0.000
I47.1 Supraventricular tachycardia
0.831 0.169 0.000
I10-I15 Hypertensive diseases
0.830 0.170 0.000
Chapter VI Diseases of the nervous system
0.829 0.171 0.000
Y52 Agents primarily affecting the cardiovascular system
0.826 0.174 0.000
H65-H75 Diseases of middle ear and mastoid
0.826 0.174 0.000
W20-W49 Exposure to inanimate mechanical forces
0.825 0.175 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.825 0.175 0.000
M35.1 Other overlap syndromes
0.822 0.178 0.000
S02 Fracture of skull and facial bones
0.819 0.181 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.817 0.183 0.000
T79-T79 Certain early complications of trauma
0.816 0.184 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.815 0.185 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.815 0.185 0.000
N71 Inflammatory disease of uterus, except cervix
0.813 0.187 0.000
N23 Unspecified renal colic
0.811 0.189 0.000
F17.1 Harmful use
0.806 0.194 0.000
M46 Other inflammatory spondylopathies
0.804 0.196 0.000
Y00-Y09 Assault
0.804 0.196 0.000
M24.5 Contracture of joint
0.803 0.197 0.000
A04 Other bacterial intestinal infections
0.799 0.201 0.000
A80-A89 Viral infections of the central nervous system
0.799 0.201 0.000
I31 Other diseases of pericardium
0.798 0.202 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.796 0.204 0.000
V20-V29 Motorcycle rider injured in transport accident
0.796 0.204 0.000
M25.8 Other specified joint disorders
0.795 0.205 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.793 0.207 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.792 0.208 0.000
I36 Nonrheumatic tricuspid valve disorders
0.788 0.212 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.787 0.212 0.000
Chapter XXII Codes for special purposes
0.786 0.214 0.000
H80-H83 Diseases of inner ear
0.784 0.216 0.000
M60-M63 Disorders of muscles
0.782 0.218 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.781 0.219 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.780 0.220 0.000
I15 Secondary hypertension
0.779 0.220 0.000
M25.77 Osteophyte (Ankle and foot)
0.779 0.221 0.000
F31 Bipolar affective disorder
0.779 0.221 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.778 0.222 0.000
W50-W64 Exposure to animate mechanical forces
0.778 0.222 0.000
M80-M85 Disorders of bone density and structure
0.776 0.224 0.000
Y43 Primarily systemic agents
0.774 0.226 0.000
I49 Other cardiac arrhythmias
0.772 0.228 0.000
M31 Other necrotising vasculopathies
0.772 0.228 0.000
S01.3 Open wound of ear
0.772 0.228 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.771 0.229 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.770 0.229 0.000
H90.3 Sensorineural hearing loss, bilateral
0.770 0.230 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.769 0.231 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.769 0.231 0.000
W00-W19 Falls
0.769 0.231 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.768 0.232 0.000
I50 Heart failure
0.768 0.232 0.000
S01.8 Open wound of other parts of head
0.768 0.232 0.000
N20.9 Urinary calculus, unspecified
0.767 0.233 0.000
M20 Acquired deformities of fingers and toes
0.767 0.233 0.000
T66-T78 Other and unspecified effects of external causes
0.766 0.234 0.000
S90-S99 Injuries to the ankle and foot
0.765 0.235 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.765 0.235 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.764 0.236 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.763 0.237 0.000
Y44 Agents primarily affecting blood constituents
0.758 0.241 0.000
M43 Other deforming dorsopathies
0.758 0.242 0.000
S01.0 Open wound of scalp
0.758 0.242 0.000
H71 Cholesteatoma of middle ear
0.757 0.243 0.000
M48.09 Spinal stenosis (Site unspecified)
0.757 0.243 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.755 0.245 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.754 0.246 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.754 0.246 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.753 0.247 0.000
M91-M94 Chondropathies
0.752 0.248 0.000
Y57 Other and unspecified drugs and medicaments
0.749 0.251 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.746 0.254 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.745 0.255 0.000
F33 Recurrent depressive disorder
0.744 0.256 0.000
M35.7 Hypermobility syndrome
0.744 0.256 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.744 0.256 0.000
I15.1 Hypertension secondary to other renal disorders
0.743 0.257 0.000
T00-T07 Injuries involving multiple body regions
0.741 0.259 0.000
M22.4 Chondromalacia patellae
0.740 0.260 0.000
I47.0 Reentry ventricular arrhythmia
0.740 0.260 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.740 0.260 0.000
H90.2 Conductive hearing loss, unspecified
0.738 0.262 0.000
H90.5 Sensorineural hearing loss, unspecified
0.737 0.263 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.736 0.264 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.734 0.266 0.000
G70-G73 Diseases of myoneural junction and muscle
0.734 0.266 0.000
M30 Polyarteritis nodosa and related conditions
0.731 0.269 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.731 0.269 0.000
M89 Other disorders of bone
0.731 0.269 0.000
M22.8 Other disorders of patella
0.729 0.271 0.000
M45 Ankylosing spondylitis
0.728 0.272 0.000
F99-F99 Unspecified mental disorder
0.728 0.272 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.728 0.272 0.000
N02.8 Other
0.727 0.273 0.000
M22.2 Patellofemoral disorders
0.727 0.273 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.726 0.274 0.000
T51 Toxic effect of alcohol
0.725 0.275 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.724 0.276 0.000
X50-X57 Overexertion, travel and privation
0.723 0.277 0.000
H66 Suppurative and unspecified otitis media
0.723 0.277 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.723 0.277 0.000
V40-V49 Car occupant injured in transport accident
0.722 0.278 0.000
M25.74 Osteophyte (Hand)
0.722 0.278 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.720 0.280 0.000
I45.5 Other specified heart block
0.720 0.280 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F03 Unspecified dementia
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M34 Systemic sclerosis
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M25.9 Joint disorder, unspecified
0.716 0.284 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.716 0.284 0.000
N99-N99 Other disorders of the genitourinary system
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.284 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.715 0.285 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.715 0.285 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.715 0.285 0.000
B99-B99 Other infectious diseases
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.285 0.000
Y10-Y34 Event of undetermined intent
0.714 0.285 0.000
X85-X99 Assault
0.714 0.285 0.000
X30-X39 Exposure to forces of nature
0.714 0.285 0.000
X10-X19 Contact with heat and hot substances
0.714 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.285 0.000
W75-W84 Other accidental threats to breathing
0.714 0.285 0.000
W65-W74 Accidental drowning and submersion
0.714 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.285 0.000
V95-V97 Air and space transport accidents
0.714 0.285 0.000
V90-V94 Water transport accidents
0.714 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.285 0.000
M24.0 Loose body in joint
0.714 0.286 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.712 0.288 0.000
M35.0 Sicca syndrome [Sjogren]
0.712 0.288 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.712 0.288 0.000
Q80-Q89 Other congenital malformations
0.711 0.289 0.000
N02.9 Unspecified
0.711 0.289 0.000
V80-V89 Other land transport accidents
0.709 0.291 0.000
M49 Spondylopathies in diseases classified elsewhere
0.709 0.291 0.000
B65-B83 Helminthiases
0.709 0.291 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.709 0.291 0.000
T90 Sequelae of injuries of head
0.709 0.291 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.707 0.293 0.000
S10-S19 Injuries to the neck
0.707 0.293 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.705 0.294 0.000
M35.8 Other specified systemic involvement of connective tissue
0.705 0.294 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.705 0.294 0.000
M35.5 Multifocal fibrosclerosis
0.705 0.294 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.705 0.294 0.000
M35.2 Behcet's disease
0.705 0.294 0.000
I12 Hypertensive renal disease
0.705 0.295 0.000
X60-X84 Intentional self-harm
0.704 0.296 0.000
M00-M03 Infectious arthropathies
0.703 0.297 0.000
F17.2 Dependence syndrome
0.702 0.298 0.000
T23 Burn and corrosion of wrist and hand
0.702 0.298 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.701 0.299 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.701 0.299 0.000
X20-X29 Contact with venomous animals and plants
0.701 0.299 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.700 0.299 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.699 0.301 0.000
S05 Injury of eye and orbit
0.699 0.301 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.697 0.303 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.696 0.304 0.000
Y40 Systemic antibiotics
0.696 0.304 0.000
N21 Calculus of lower urinary tract
0.696 0.304 0.000
I00-I02 Acute rheumatic fever
0.695 0.305 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.693 0.307 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.693 0.307 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.693 0.307 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.693 0.307 0.000
T36 Poisoning by systemic antibiotics
0.693 0.307 0.000
M48.02 Spinal stenosis (Cervical region)
0.693 0.307 0.000
N05.9 Unspecified
0.693 0.307 0.000
M20.2 Hallux rigidus
0.692 0.308 0.000
I37 Pulmonary valve disorders
0.690 0.310 0.000
I49.3 Ventricular premature depolarisation
0.690 0.310 0.000
H92 Otalgia and effusion of ear
0.689 0.311 0.000
T17 Foreign body in respiratory tract
0.689 0.311 0.000
I52 Other heart disorders in diseases classified elsewhere
0.689 0.311 0.000
I48 Atrial fibrillation and flutter
0.689 0.311 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.689 0.311 0.000
I41 Myocarditis in diseases classified elsewhere
0.689 0.311 0.000
I40 Acute myocarditis
0.689 0.311 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.689 0.311 0.000
I32 Pericarditis in diseases classified elsewhere
0.689 0.311 0.000
M43.1 Spondylolisthesis
0.688 0.312 0.000
S01.2 Open wound of nose
0.688 0.312 0.000
Y59 Other and unspecified vaccines and biological substances
0.687 0.313 0.000
Y58 Bacterial vaccines
0.687 0.313 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.687 0.313 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.687 0.313 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.687 0.313 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.687 0.313 0.000
Y48 Anaesthetics and therapeutic gases
0.687 0.313 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.687 0.313 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.687 0.313 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.687 0.313 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.687 0.313 0.000
Y98 Lifestyle-related condition
0.687 0.313 0.000
Y97 Environmental-pollution-related condition
0.687 0.313 0.000
Y96 Work-related condition
0.687 0.313 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.687 0.313 0.000
F34 Persistent mood [affective] disorders
0.687 0.313 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.687 0.313 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.686 0.314 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.684 0.316 0.000
N06 Isolated proteinuria with specified morphological lesion
0.684 0.316 0.000
N01 Rapidly progressive nephritic syndrome
0.684 0.316 0.000
N00 Acute nephritic syndrome
0.684 0.316 0.000
M24.9 Joint derangement, unspecified
0.684 0.316 0.000
M24.7 Protrusio acetabuli
0.684 0.316 0.000
M24.6 Ankylosis of joint
0.684 0.316 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.684 0.316 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.683 0.317 0.000
N73.8 Other specified female pelvic inflammatory diseases
0.681 0.319 0.000
N73.5 Female pelvic peritonitis, unspecified
0.681 0.319 0.000
N73.4 Female chronic pelvic peritonitis
0.681 0.319 0.000
N73.3 Female acute pelvic peritonitis
0.681 0.319 0.000
N73.2 Unspecified parametritis and pelvic cellulitis
0.681 0.319 0.000
N73.1 Chronic parametritis and pelvic cellulitis
0.681 0.319 0.000
N73.0 Acute parametritis and pelvic cellulitis
0.681 0.319 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.681 0.319 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.680 0.320 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.680 0.320 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.679 0.320 0.000
M24.2 Disorder of ligament
0.679 0.321 0.000
G71 Primary disorders of muscles
0.679 0.321 0.000
I44.1 Atrioventricular block, second degree
0.679 0.321 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.679 0.321 0.000
T43.2 Other and unspecified antidepressants
0.678 0.322 0.000
I05-I09 Chronic rheumatic heart diseases
0.678 0.322 0.000
S50 Superficial injury of forearm
0.678 0.322 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.677 0.323 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.677 0.323 0.000
F70-F79 Mental retardation
0.677 0.323 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.676 0.324 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.675 0.325 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.673 0.327 0.000
N03 Chronic nephritic syndrome
0.672 0.328 0.000
N05.1 Focal and segmental glomerular lesions
0.672 0.328 0.000
M50-M54 Other dorsopathies
0.672 0.328 0.000
I44.5 Left posterior fascicular block
0.671 0.328 0.000
I44.4 Left anterior fascicular block
0.671 0.328 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.670 0.330 0.000
I44.6 Other and unspecified fascicular block
0.670 0.330 0.000
S08 Traumatic amputation of part of head
0.669 0.331 0.000
S07 Crushing injury of head
0.669 0.331 0.000
S04 Injury of cranial nerves
0.669 0.331 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.669 0.331 0.000
V10-V19 Pedal cyclist injured in transport accident
0.669 0.331 0.000
H69 Other disorders of Eustachian tube
0.668 0.332 0.000
M24.51 Contracture of joint (Shoulder region)
0.668 0.332 0.000
N05.2 Diffuse membranous glomerulonephritis
0.668 0.332 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.666 0.334 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.664 0.336 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.664 0.336 0.000
Y00 Assault by blunt object
0.663 0.337 0.000
M20.0 Deformity of finger(s)
0.663 0.337 0.000
F60-F69 Disorders of adult personality and behaviour
0.663 0.337 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.662 0.338 0.000
I44.3 Other and unspecified atrioventricular block
0.662 0.338 0.000
N71.9 Inflammatory disease of uterus, unspecified
0.661 0.338 0.000
Q00-Q07 Congenital malformations of the nervous system
0.661 0.339 0.000
H80 Otosclerosis
0.660 0.340 0.000
S02.4 Fracture of malar and maxillary bones
0.660 0.340 0.000
I50.0 Congestive heart failure
0.660 0.340 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.659 0.341 0.000
Q50-Q56 Congenital malformations of genital organs
0.659 0.341 0.000
M80 Osteoporosis with pathological fracture
0.658 0.342 0.000
G20-G26 Extrapyramidal and movement disorders
0.657 0.343 0.000
S02.2 Fracture of nasal bones
0.657 0.343 0.000
S02.3 Fracture of orbital floor
0.657 0.343 0.000
W25 Contact with sharp glass
0.657 0.343 0.000
I71 Aortic aneurysm and dissection
0.657 0.343 0.000
I12.0 Hypertensive renal disease with renal failure
0.656 0.344 0.000
M25.4 Effusion of joint
0.656 0.344 0.000
H60-H62 Diseases of external ear
0.655 0.345 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.655 0.345 0.000
I31.3 Pericardial effusion (noninflammatory)
0.655 0.345 0.000
N71.1 Chronic inflammatory disease of uterus
0.654 0.346 0.000
S52 Fracture of forearm
0.654 0.346 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.653 0.347 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.651 0.349 0.000
Q35-Q37 Cleft lip and cleft palate
0.651 0.349 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.651 0.349 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.650 0.350 0.000
H66.3 Other chronic suppurative otitis media
0.649 0.351 0.000
G50 Disorders of trigeminal nerve
0.649 0.351 0.000
I49.8 Other specified cardiac arrhythmias
0.649 0.351 0.000
T51.0 Ethanol
0.649 0.351 0.000
T43.9 Psychotropic drug, unspecified
0.648 0.352 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.648 0.352 0.000
T43.6 Psychostimulants with abuse potential
0.648 0.352 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.648 0.352 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.648 0.352 0.000
M25.2 Flail joint
0.648 0.352 0.000
M25.1 Fistula of joint
0.648 0.352 0.000
M25.0 Haemarthrosis
0.648 0.352 0.000
I45.8 Other specified conduction disorders
0.647 0.353 0.000
I45.4 Nonspecific intraventricular block
0.647 0.353 0.000
I45.3 Trifascicular block
0.647 0.353 0.000
I45.2 Bifascicular block
0.647 0.353 0.000
I45.0 Right fascicular block
0.647 0.353 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.647 0.353 0.000
I46 Cardiac arrest
0.646 0.353 0.000
I30 Acute pericarditis
0.646 0.354 0.000
N04 Nephrotic syndrome
0.646 0.354 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.646 0.354 0.000
B25-B34 Other viral diseases
0.645 0.355 0.000
M86 Osteomyelitis
0.644 0.356 0.000
M46.4 Discitis, unspecified
0.644 0.356 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.644 0.356 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.644 0.356 0.000
A04.4 Other intestinal Escherichia coli infections
0.644 0.356 0.000
G58 Other mononeuropathies
0.644 0.356 0.000
S43.0 Dislocation of shoulder joint
0.643 0.357 0.000
M25.84 Other specified joint disorders (Hand)
0.642 0.357 0.000
T56 Toxic effect of metals
0.642 0.358 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.642 0.358 0.000
M21 Other acquired deformities of limbs
0.642 0.358 0.000
M22.1 Recurrent subluxation of patella
0.642 0.358 0.000
M22.9 Disorder of patella, unspecified
0.642 0.358 0.000
M22.0 Recurrent dislocation of patella
0.642 0.358 0.000
S02.8 Fractures of other skull and facial bones
0.641 0.359 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.640 0.359 0.000
M48.9 Spondylopathy, unspecified
0.640 0.360 0.000
M48.8 Other specified spondylopathies
0.640 0.360 0.000
M48.4 Fatigue fracture of vertebra
0.640 0.360 0.000
M48.3 Traumatic spondylopathy
0.640 0.360 0.000
M48.2 Kissing spine
0.640 0.360 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.640 0.360 0.000
M31.3 Wegener's granulomatosis
0.640 0.360 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.640 0.360 0.000
W44 Foreign body entering into or through eye or natural orifice
0.639 0.361 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.639 0.361 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.639 0.361 0.000
T68 Hypothermia
0.638 0.362 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.638 0.362 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.637 0.363 0.000
S06 Intracranial injury
0.637 0.363 0.000
M25.76 Osteophyte (Lower leg)
0.637 0.363 0.000
M25.71 Osteophyte (Shoulder region)
0.637 0.363 0.000
N60 Benign mammary dysplasia
0.635 0.365 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.635 0.365 0.000
M25.86 Other specified joint disorders (Lower leg)
0.635 0.365 0.000
G30-G32 Other degenerative diseases of the nervous system
0.634 0.366 0.000
S40 Superficial injury of shoulder and upper arm
0.633 0.367 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.632 0.368 0.000
Y52.1 Calcium-channel blockers
0.631 0.369 0.000
I99 Other and unspecified disorders of circulatory system
0.630 0.370 0.000
B15-B19 Viral hepatitis
0.629 0.370 0.000
F30 Manic episode
0.629 0.371 0.000
T20 Burn and corrosion of head and neck
0.629 0.371 0.000
B02 Zoster [herpes zoster]
0.629 0.371 0.000
T42.1 Iminostilbenes
0.629 0.371 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.628 0.372 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.628 0.372 0.000
H90.0 Conductive hearing loss, bilateral
0.628 0.372 0.000
S01.7 Multiple open wounds of head
0.628 0.372 0.000
W08 Fall involving other furniture
0.628 0.372 0.000
F38 Other mood [affective] disorders
0.627 0.373 0.000
F39 Unspecified mood [affective] disorder
0.627 0.373 0.000
M62 Other disorders of muscle
0.627 0.373 0.000
I42 Cardiomyopathy
0.626 0.374 0.000
A87 Viral meningitis
0.624 0.376 0.000
I33 Acute and subacute endocarditis
0.624 0.376 0.000
T45.0 Antiallergic and antiemetic drugs
0.624 0.376 0.000
G57 Mononeuropathies of lower limb
0.624 0.376 0.000
G71.0 Muscular dystrophy
0.624 0.376 0.000
H93 Other disorders of ear, not elsewhere classified
0.623 0.377 0.000
I70 Atherosclerosis
0.623 0.377 0.000
H81 Disorders of vestibular function
0.623 0.377 0.000
M84 Disorders of continuity of bone
0.623 0.377 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.622 0.378 0.000
F80-F89 Disorders of psychological development
0.622 0.378 0.000
M90 Osteopathies in diseases classified elsewhere
0.621 0.378 0.000
W18 Other fall on same level
0.621 0.379 0.000
S20-S29 Injuries to the thorax
0.621 0.379 0.000
M24.54 Contracture of joint (Hand)
0.620 0.379 0.000
W20 Struck by thrown, projected or falling object
0.620 0.380 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.620 0.380 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.618 0.382 0.000
M24.18 Other articular cartilage disorders (Other)
0.618 0.382 0.000
M24.14 Other articular cartilage disorders (Hand)
0.618 0.382 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.618 0.382 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.618 0.382 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.618 0.382 0.000
N70 Salpingitis and oophoritis
0.618 0.382 0.000
M89.9 Disorder of bone, unspecified
0.617 0.383 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.616 0.383 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.616 0.383 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.616 0.383 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.616 0.383 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.616 0.383 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.616 0.383 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.616 0.383 0.000
F11 Mental and behavioural disorders due to use of opioids
0.616 0.383 0.000
T93 Sequelae of injuries of lower limb
0.617 0.383 0.000
A07 Other protozoal intestinal diseases
0.616 0.384 0.000
A06 Amoebiasis
0.616 0.384 0.000
A05 Other bacterial foodborne intoxications
0.616 0.384 0.000
A03 Shigellosis
0.616 0.384 0.000
A02 Other Salmonella infections
0.616 0.384 0.000
A01 Typhoid and paratyphoid fevers
0.616 0.384 0.000
A00 Cholera
0.616 0.384 0.000
S70-S79 Injuries to the hip and thigh
0.616 0.384 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.616 0.384 0.000
Y44.2 Anticoagulants
0.615 0.385 0.000
A86 Unspecified viral encephalitis
0.615 0.385 0.000
B00 Herpesviral [herpes simplex] infections
0.615 0.385 0.000
Q24 Other congenital malformations of heart
0.614 0.386 0.000
I31.9 Disease of pericardium, unspecified
0.614 0.386 0.000
M22.3 Other derangements of patella
0.613 0.386 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.612 0.387 0.000
G81 Hemiplegia
0.612 0.388 0.000
S91 Open wound of ankle and foot
0.612 0.388 0.000
Y45.0 Opioids and related analgesics
0.612 0.388 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.611 0.389 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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