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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78199931
log Bayes Factor = 17.2832
Chromosome 9   position 140,865,334  (GRCh37) Explore rs78199931 on Ensembl!
Variant rs78199931 is part of Cluster X0156

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.995 0.005 0.000
I30-I52 Other forms of heart disease
0.993 0.007 0.000
N30-N39 Other diseases of urinary system
0.992 0.008 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.992 0.008 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.992 0.008 0.000
R30-R39 Symptoms and signs involving the urinary system
0.987 0.013 0.000
N32 Other disorders of bladder
0.985 0.015 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.985 0.015 0.000
Y83.6 Removal of other organ (partial) (total)
0.978 0.022 0.000
R35 Polyuria
0.978 0.022 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.971 0.029 0.000
M20-M25 Other joint disorders
0.971 0.029 0.000
I60-I69 Cerebrovascular diseases
0.969 0.031 0.000
M15-M19 Arthrosis
0.966 0.034 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.961 0.039 0.000
N32.8 Other specified disorders of bladder
0.961 0.039 0.000
T81 Complications of procedures, not elsewhere classified
0.958 0.042 0.000
Chapter I Certain infectious and parasitic diseases
0.956 0.044 0.000
I77 Other disorders of arteries and arterioles
0.951 0.049 0.000
M19 Other arthrosis
0.950 0.050 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.946 0.054 0.000
M65-M68 Disorders of synovium and tendon
0.943 0.057 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.942 0.058 0.000
Chapter VII Diseases of the eye and adnexa
0.935 0.065 0.000
I51 Complications and ill-defined descriptions of heart disease
0.931 0.069 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.925 0.075 0.000
M50-M54 Other dorsopathies
0.921 0.079 0.000
I50 Heart failure
0.916 0.084 0.000
M23 Internal derangement of knee
0.913 0.087 0.000
Chapter VI Diseases of the nervous system
0.913 0.087 0.000
M19.9 Arthrosis, unspecified
0.911 0.089 0.000
Chapter V Mental and behavioural disorders
0.910 0.090 0.000
B35-B49 Mycoses
0.908 0.092 0.000
I34 Nonrheumatic mitral valve disorders
0.908 0.092 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.901 0.098 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.897 0.103 0.000
S20-S29 Injuries to the thorax
0.895 0.105 0.000
M25 Other joint disorders, not elsewhere classified
0.894 0.106 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.891 0.109 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.890 0.110 0.000
I26 Pulmonary embolism
0.889 0.111 0.000
I63 Cerebral infarction
0.886 0.114 0.000
M54 Dorsalgia
0.881 0.119 0.000
M65 Synovitis and tenosynovitis
0.880 0.120 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.879 0.121 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.878 0.122 0.000
B37 Candidiasis
0.874 0.126 0.000
I46 Cardiac arrest
0.872 0.128 0.000
N35 Urethral stricture
0.871 0.129 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.869 0.131 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.868 0.132 0.000
Chapter XXI Factors influencing health status and contact with health services
0.868 0.132 0.000
I71 Aortic aneurysm and dissection
0.868 0.132 0.000
I34.0 Mitral (valve) insufficiency
0.867 0.133 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.867 0.133 0.000
I73 Other peripheral vascular diseases
0.866 0.134 0.000
I77.1 Stricture of artery
0.866 0.134 0.000
N81 Female genital prolapse
0.863 0.137 0.000
M19.0 Primary arthrosis of other joints
0.862 0.138 0.000
N81.6 Rectocele
0.860 0.140 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.860 0.140 0.000
M25.5 Pain in joint
0.859 0.141 0.000
M70-M79 Other soft tissue disorders
0.859 0.141 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.858 0.142 0.000
I27 Other pulmonary heart diseases
0.858 0.142 0.000
H30-H36 Disorders of choroid and retina
0.858 0.142 0.000
I51.8 Other ill-defined heart diseases
0.857 0.143 0.000
M18 Arthrosis of first carpometacarpal joint
0.857 0.143 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.853 0.147 0.000
I51.9 Heart disease, unspecified
0.853 0.147 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.850 0.150 0.000
I60 Subarachnoid haemorrhage
0.850 0.150 0.000
M05-M14 Inflammatory polyarthropathies
0.849 0.151 0.000
R42 Dizziness and giddiness
0.847 0.153 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.845 0.155 0.000
R20 Disturbances of skin sensation
0.844 0.156 0.000
R47-R49 Symptoms and signs involving speech and voice
0.843 0.157 0.000
M45-M49 Spondylopathies
0.842 0.158 0.000
N40-N51 Diseases of male genital organs
0.842 0.158 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.841 0.159 0.000
I50.9 Heart failure, unspecified
0.840 0.160 0.000
Z98 Other postsurgical states
0.839 0.161 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.837 0.163 0.000
B95-B98 Bacterial, viral and other infectious agents
0.837 0.163 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.833 0.167 0.000
T40.2 Other opioids
0.832 0.168 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.830 0.170 0.000
M54.5 Low back pain
0.829 0.171 0.000
I10-I15 Hypertensive diseases
0.823 0.177 0.000
N32.0 Bladder-neck obstruction
0.822 0.178 0.000
N81.1 Cystocele
0.822 0.178 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.816 0.184 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.814 0.186 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.813 0.187 0.000
N32.3 Diverticulum of bladder
0.813 0.187 0.000
M22 Disorders of patella
0.811 0.189 0.000
R33 Retention of urine
0.810 0.190 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.810 0.190 0.000
Z98.0 Intestinal bypass and anastomosis status
0.809 0.191 0.000
I50.1 Left ventricular failure
0.805 0.195 0.000
N00-N08 Glomerular diseases
0.805 0.195 0.000
I77.6 Arteritis, unspecified
0.805 0.195 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.805 0.195 0.000
Z87 Personal history of other diseases and conditions
0.803 0.197 0.000
S90-S99 Injuries to the ankle and foot
0.802 0.198 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.802 0.198 0.000
H35 Other retinal disorders
0.800 0.200 0.000
R30 Pain associated with micturition
0.800 0.200 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.798 0.202 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.798 0.202 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.796 0.204 0.000
M40-M43 Deforming dorsopathies
0.796 0.204 0.000
B37.0 Candidal stomatitis
0.795 0.205 0.000
H53-H54 Visual disturbances and blindness
0.795 0.205 0.000
R10 Abdominal and pelvic pain
0.795 0.205 0.000
M65.3 Trigger finger
0.794 0.206 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.792 0.208 0.000
M91-M94 Chondropathies
0.790 0.210 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.788 0.212 0.000
I45 Other conduction disorders
0.787 0.213 0.000
I63.9 Cerebral infarction, unspecified
0.787 0.213 0.000
N32.1 Vesicointestinal fistula
0.785 0.215 0.000
N35.9 Urethral stricture, unspecified
0.785 0.215 0.000
N81.5 Vaginal enterocele
0.783 0.217 0.000
S80-S89 Injuries to the knee and lower leg
0.783 0.217 0.000
N39 Other disorders of urinary system
0.782 0.218 0.000
N99-N99 Other disorders of the genitourinary system
0.781 0.219 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.781 0.219 0.000
X60-X84 Intentional self-harm
0.780 0.220 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.780 0.220 0.000
M25.56 Pain in joint (Lower leg)
0.778 0.222 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.777 0.223 0.000
Y95 Nosocomial condition
0.777 0.223 0.000
T79-T79 Certain early complications of trauma
0.777 0.223 0.000
I46.0 Cardiac arrest with successful resuscitation
0.776 0.224 0.000
M23.3 Other meniscus derangements
0.775 0.225 0.000
I72 Other aneurysm
0.775 0.225 0.000
W00-W19 Falls
0.774 0.226 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.773 0.227 0.000
I38 Endocarditis, valve unspecified
0.772 0.228 0.000
M67 Other disorders of synovium and tendon
0.769 0.231 0.000
I27.2 Other secondary pulmonary hypertension
0.769 0.231 0.000
Z90.7 Acquired absence of genital organ(s)
0.768 0.232 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.767 0.233 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.766 0.234 0.000
I73.9 Peripheral vascular disease, unspecified
0.766 0.234 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.765 0.235 0.000
N32.9 Bladder disorder, unspecified
0.765 0.235 0.000
B37.8 Candidiasis of other sites
0.764 0.236 0.000
Chapter II Neoplasms
0.764 0.236 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.762 0.238 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.761 0.239 0.000
N30 Cystitis
0.758 0.242 0.000
M31 Other necrotising vasculopathies
0.758 0.242 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.756 0.244 0.000
I69 Sequelae of cerebrovascular disease
0.756 0.244 0.000
M25.57 Pain in joint (Ankle and foot)
0.756 0.244 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.755 0.245 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.755 0.245 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.754 0.246 0.000
Chapter XXII Codes for special purposes
0.753 0.247 0.000
H10-H13 Disorders of conjunctiva
0.750 0.250 0.000
S50-S59 Injuries to the elbow and forearm
0.750 0.250 0.000
I31 Other diseases of pericardium
0.750 0.250 0.000
R10.2 Pelvic and perineal pain
0.750 0.250 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.750 0.250 0.000
Z98.1 Arthrodesis status
0.749 0.251 0.000
I10 Essential (primary) hypertension
0.746 0.254 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.745 0.255 0.000
R32 Unspecified urinary incontinence
0.745 0.255 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.744 0.256 0.000
W20-W49 Exposure to inanimate mechanical forces
0.743 0.257 0.000
Z87.1 Personal history of diseases of the digestive system
0.740 0.260 0.000
T66-T78 Other and unspecified effects of external causes
0.740 0.260 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.737 0.263 0.000
M21 Other acquired deformities of limbs
0.737 0.263 0.000
T39.1 4-Aminophenol derivatives
0.737 0.263 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.737 0.263 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.736 0.264 0.000
N39.4 Other specified urinary incontinence
0.736 0.264 0.000
I70 Atherosclerosis
0.735 0.265 0.000
N41 Inflammatory diseases of prostate
0.735 0.265 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.734 0.266 0.000
R13 Dysphagia
0.733 0.267 0.000
I63.8 Other cerebral infarction
0.733 0.267 0.000
M25.50 Pain in joint (Multiple sites)
0.733 0.267 0.000
M65.34 Trigger finger-Hand
0.733 0.267 0.000
Y83.8 Other surgical procedures
0.732 0.268 0.000
R10.3 Pain localised to other parts of lower abdomen
0.730 0.270 0.000
M54.3 Sciatica
0.728 0.272 0.000
M86-M90 Other osteopathies
0.728 0.272 0.000
G90-G99 Other disorders of the nervous system
0.728 0.272 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.727 0.273 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.726 0.273 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.725 0.274 0.000
Z89 Acquired absence of limb
0.725 0.275 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.725 0.275 0.000
M23.8 Other internal derangements of knee
0.724 0.276 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.723 0.277 0.000
N93 Other abnormal uterine and vaginal bleeding
0.723 0.277 0.000
M54.9 Dorsalgia, unspecified
0.722 0.278 0.000
M80-M85 Disorders of bone density and structure
0.722 0.278 0.000
R46 Symptoms and signs involving appearance and behaviour
0.721 0.279 0.000
N20-N23 Urolithiasis
0.721 0.279 0.000
M19.1 Posttraumatic arthrosis of other joints
0.721 0.279 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.720 0.279 0.000
I62 Other nontraumatic intracranial haemorrhage
0.720 0.280 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.719 0.281 0.000
I74 Arterial embolism and thrombosis
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
H35.8 Other specified retinal disorders
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.283 0.000
T86 Failure and rejection of transplanted organs and tissues
0.716 0.283 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.283 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.716 0.284 0.000
Y84.6 Urinary catheterisation
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.284 0.000
Y10-Y34 Event of undetermined intent
0.715 0.284 0.000
Y00-Y09 Assault
0.715 0.284 0.000
X85-X99 Assault
0.715 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.284 0.000
X50-X57 Overexertion, travel and privation
0.715 0.284 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.284 0.000
X30-X39 Exposure to forces of nature
0.715 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.284 0.000
X10-X19 Contact with heat and hot substances
0.715 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.284 0.000
W75-W84 Other accidental threats to breathing
0.715 0.284 0.000
W65-W74 Accidental drowning and submersion
0.715 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.284 0.000
V95-V97 Air and space transport accidents
0.715 0.284 0.000
V90-V94 Water transport accidents
0.715 0.284 0.000
V80-V89 Other land transport accidents
0.715 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.284 0.000
R23 Other skin changes
0.715 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.715 0.285 0.000
R20.2 Paraesthesia of skin
0.714 0.286 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.714 0.286 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.712 0.288 0.000
I52 Other heart disorders in diseases classified elsewhere
0.712 0.288 0.000
I48 Atrial fibrillation and flutter
0.712 0.288 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.712 0.288 0.000
I41 Myocarditis in diseases classified elsewhere
0.712 0.288 0.000
I40 Acute myocarditis
0.712 0.288 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.712 0.288 0.000
I37 Pulmonary valve disorders
0.712 0.288 0.000
I36 Nonrheumatic tricuspid valve disorders
0.712 0.288 0.000
I32 Pericarditis in diseases classified elsewhere
0.712 0.288 0.000
I30 Acute pericarditis
0.712 0.288 0.000
N37 Urethral disorders in diseases classified elsewhere
0.712 0.288 0.000
N34 Urethritis and urethral syndrome
0.712 0.288 0.000
N33 Bladder disorders in diseases classified elsewhere
0.712 0.288 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.711 0.289 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.711 0.289 0.000
V20-V29 Motorcycle rider injured in transport accident
0.711 0.289 0.000
H34 Retinal vascular occlusions
0.711 0.289 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.710 0.290 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.710 0.290 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.710 0.290 0.000
M75 Shoulder lesions
0.709 0.291 0.000
A30-A49 Other bacterial diseases
0.709 0.291 0.000
I33 Acute and subacute endocarditis
0.708 0.292 0.000
G40-G47 Episodic and paroxysmal disorders
0.708 0.292 0.000
R36 Urethral discharge
0.707 0.292 0.000
R34 Anuria and oliguria
0.707 0.292 0.000
N36 Other disorders of urethra
0.707 0.293 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.707 0.293 0.000
N32.4 Rupture of bladder, nontraumatic
0.706 0.293 0.000
N32.2 Vesical fistula, not elsewhere classified
0.706 0.293 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.707 0.293 0.000
Y83.5 Amputation of limb(s)
0.706 0.294 0.000
Y83.0 Surgical operation with transplant of whole organ
0.706 0.294 0.000
M47 Spondylosis
0.706 0.294 0.000
N25-N29 Other disorders of kidney and ureter
0.705 0.295 0.000
F60-F69 Disorders of adult personality and behaviour
0.704 0.296 0.000
M51 Other intervertebral disk disorders
0.704 0.296 0.000
R49 Voice disturbances
0.704 0.296 0.000
I78 Diseases of capillaries
0.703 0.297 0.000
B37.9 Candidiasis, unspecified
0.703 0.297 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.703 0.297 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.702 0.298 0.000
R21 Rash and other nonspecific skin eruption
0.701 0.299 0.000
F80-F89 Disorders of psychological development
0.700 0.299 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.700 0.300 0.000
S40-S49 Injuries to the shoulder and upper arm
0.699 0.301 0.000
M22.2 Patellofemoral disorders
0.699 0.301 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.699 0.301 0.000
F17.1 Harmful use
0.699 0.301 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.698 0.302 0.000
T93 Sequelae of injuries of lower limb
0.698 0.302 0.000
N40 Hyperplasia of prostate
0.697 0.303 0.000
M10 Gout
0.697 0.303 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.697 0.303 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.696 0.304 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.696 0.304 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.696 0.304 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.696 0.304 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.696 0.304 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.696 0.304 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.696 0.304 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.696 0.304 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.696 0.304 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.696 0.304 0.000
T36 Poisoning by systemic antibiotics
0.696 0.304 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.696 0.304 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.696 0.304 0.000
M34 Systemic sclerosis
0.696 0.304 0.000
M33 Dermatopolymyositis
0.696 0.304 0.000
M32 Systemic lupus erythematosus
0.696 0.304 0.000
M30 Polyarteritis nodosa and related conditions
0.696 0.304 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.695 0.305 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.695 0.305 0.000
M15 Polyarthrosis
0.693 0.307 0.000
M54.59 Low back pain (Site unspecified)
0.692 0.308 0.000
M24 Other specific joint derangements
0.692 0.308 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.692 0.308 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.691 0.309 0.000
H35.3 Degeneration of macula and posterior pole
0.691 0.309 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.691 0.309 0.000
S70-S79 Injuries to the hip and thigh
0.690 0.309 0.000
G20-G26 Extrapyramidal and movement disorders
0.690 0.310 0.000
I28 Other diseases of pulmonary vessels
0.689 0.311 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.689 0.311 0.000
Chapter X Diseases of the respiratory system
0.688 0.312 0.000
G56 Mononeuropathies of upper limb
0.687 0.313 0.000
T81.9 Unspecified complication of procedure
0.687 0.313 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.687 0.313 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.687 0.313 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.687 0.313 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.687 0.313 0.000
B99-B99 Other infectious diseases
0.685 0.314 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.685 0.314 0.000
B65-B83 Helminthiases
0.685 0.314 0.000
B50-B64 Protozoal diseases
0.685 0.314 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.685 0.314 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.685 0.314 0.000
A80-A89 Viral infections of the central nervous system
0.685 0.314 0.000
A75-A79 Rickettsioses
0.685 0.314 0.000
A70-A74 Other diseases caused by chlamydiae
0.685 0.314 0.000
A65-A69 Other spirochaetal diseases
0.685 0.314 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.685 0.314 0.000
A20-A28 Certain zoonotic bacterial diseases
0.685 0.314 0.000
A15-A19 Tuberculosis
0.685 0.314 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.685 0.314 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.684 0.316 0.000
S20 Superficial injury of thorax
0.684 0.316 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.683 0.317 0.000
I77.8 Other specified disorders of arteries and arterioles
0.682 0.318 0.000
I77.5 Necrosis of artery
0.682 0.318 0.000
I77.4 Coeliac artery compression syndrome
0.682 0.318 0.000
I77.3 Arterial fibromuscular dysplasia
0.682 0.318 0.000
I77.2 Rupture of artery
0.682 0.318 0.000
I77.0 Arteriovenous fistula, acquired
0.682 0.318 0.000
I42 Cardiomyopathy
0.682 0.318 0.000
M19.8 Other specified arthrosis
0.681 0.318 0.000
M19.2 Other secondary arthrosis
0.681 0.318 0.000
T51 Toxic effect of alcohol
0.681 0.319 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.681 0.319 0.000
M11 Other crystal arthropathies
0.681 0.319 0.000
M54.56 Low back pain (Lumbar region)
0.681 0.319 0.000
S27 Injury of other and unspecified intrathoracic organs
0.681 0.319 0.000
T92 Sequelae of injuries of upper limb
0.681 0.319 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.680 0.320 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.679 0.321 0.000
H53 Visual disturbances
0.679 0.321 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.678 0.322 0.000
R45 Symptoms and signs involving emotional state
0.678 0.322 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.678 0.322 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.678 0.322 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.678 0.322 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.678 0.322 0.000
T82.3 Mechanical complication of other vascular grafts
0.678 0.322 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.678 0.322 0.000
T82.1 Mechanical complication of cardiac electronic device
0.678 0.322 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.678 0.322 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.678 0.322 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.677 0.323 0.000
B15-B19 Viral hepatitis
0.677 0.323 0.000
F99-F99 Unspecified mental disorder
0.677 0.323 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.676 0.324 0.000
M66 Spontaneous rupture of synovium and tendon
0.676 0.324 0.000
Y83.9 Surgical procedure, unspecified
0.676 0.324 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.675 0.325 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.673 0.326 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.673 0.327 0.000
T39.0 Salicylates
0.672 0.328 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.672 0.328 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.672 0.328 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.671 0.329 0.000
H55-H59 Other disorders of eye and adnexa
0.670 0.329 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.670 0.330 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.670 0.330 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.670 0.330 0.000
I51.6 Cardiovascular disease, unspecified
0.667 0.332 0.000
I51.5 Myocardial degeneration
0.667 0.332 0.000
I51.4 Myocarditis, unspecified
0.667 0.332 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.667 0.332 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.667 0.332 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.667 0.332 0.000
I51.0 Cardiac septal defect, acquired
0.667 0.332 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.667 0.333 0.000
N50 Other disorders of male genital organs
0.667 0.333 0.000
G30-G32 Other degenerative diseases of the nervous system
0.666 0.334 0.000
R30.0 Dysuria
0.666 0.334 0.000
R17 Unspecified jaundice
0.665 0.335 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.665 0.335 0.000
H46 Optic neuritis
0.664 0.336 0.000
N10-N16 Renal tubulo-interstitial diseases
0.664 0.336 0.000
M77 Other enthesopathies
0.663 0.337 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.662 0.338 0.000
M53 Other dorsopathies, not elsewhere classified
0.660 0.340 0.000
M07 Psoriatic and enteropathic arthropathies
0.658 0.342 0.000
G70-G73 Diseases of myoneural junction and muscle
0.658 0.342 0.000
Chapter XI Diseases of the digestive system
0.658 0.342 0.000
W07 Fall involving chair
0.657 0.343 0.000
Q60-Q64 Congenital malformations of the urinary system
0.657 0.343 0.000
M48 Other spondylopathies
0.657 0.343 0.000
Z96 Presence of other functional implants
0.657 0.343 0.000
I27.0 Primary pulmonary hypertension
0.657 0.343 0.000
M41 Scoliosis
0.656 0.344 0.000
M19.94 Arthrosis, unspecified (Hand)
0.655 0.344 0.000
M23.9 Internal derangement of knee, unspecified
0.655 0.345 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.655 0.345 0.000
M23.5 Chronic instability of knee
0.655 0.345 0.000
M23.1 Discoid meniscus (congenital)
0.655 0.345 0.000
M23.0 Cystic meniscus
0.655 0.345 0.000
Z97 Presence of other devices
0.654 0.345 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.654 0.346 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.654 0.346 0.000
M19.98 Arthrosis, unspecified (Other)
0.653 0.347 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.652 0.348 0.000
F70-F79 Mental retardation
0.652 0.348 0.000
R47 Speech disturbances, not elsewhere classified
0.651 0.348 0.000
B48 Other mycoses, not elsewhere classified
0.651 0.349 0.000
B47 Mycetoma
0.651 0.349 0.000
B46 Zygomycosis
0.651 0.349 0.000
B45 Cryptococcosis
0.651 0.349 0.000
B44 Aspergillosis
0.651 0.349 0.000
B43 Chromomycosis and phaeomycotic abscess
0.651 0.349 0.000
B42 Sporotrichosis
0.651 0.349 0.000
B41 Paracoccidioidomycosis
0.651 0.349 0.000
B40 Blastomycosis
0.651 0.349 0.000
B39 Histoplasmosis
0.651 0.349 0.000
B38 Coccidioidomycosis
0.651 0.349 0.000
B36 Other superficial mycoses
0.651 0.349 0.000
B35 Dermatophytosis
0.651 0.349 0.000
B49 Unspecified mycosis
0.651 0.349 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.651 0.349 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.651 0.349 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.651 0.349 0.000
S22.3 Fracture of rib
0.651 0.349 0.000
I46.9 Cardiac arrest, unspecified
0.650 0.350 0.000
N02 Recurrent and persistent haematuria
0.650 0.350 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.648 0.352 0.000
M23.4 Loose body in knee
0.648 0.352 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.648 0.352 0.000
N89 Other noninflammatory disorders of vagina
0.647 0.353 0.000
V10-V19 Pedal cyclist injured in transport accident
0.647 0.353 0.000
R82 Other abnormal findings in urine
0.647 0.353 0.000
B25-B34 Other viral diseases
0.647 0.353 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.646 0.354 0.000
R43 Disturbances of smell and taste
0.646 0.354 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.645 0.355 0.000
I73.0 Raynaud's syndrome
0.645 0.355 0.000
Y83.4 Other reconstructive surgery
0.645 0.355 0.000
M67.8 Other specified disorders of synovium and tendon
0.644 0.355 0.000
S80 Superficial injury of lower leg
0.643 0.356 0.000
G47 Sleep disorders
0.643 0.357 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.643 0.357 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.643 0.357 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.643 0.357 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.643 0.357 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.643 0.357 0.000
S29 Other and unspecified injuries of thorax
0.641 0.358 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.641 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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