TreeWAS – Variant ID: rs78250596

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
I10-I15 Hypertensive diseases	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	1.000	0.000
I10 Essential (primary) hypertension	0.999	0.001
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.999	0.001
Chapter XIV Diseases of the genitourinary system	0.999	0.001
C50-C50 Malignant neoplasm of breast	0.998	0.002
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.997	0.003
N40-N51 Diseases of male genital organs	0.997	0.003
C50 Malignant neoplasm of breast	0.996	0.004
Chapter IV Endocrine, nutritional and metabolic diseases	0.993	0.007
C50.9 Breast, unspecified	0.989	0.011
Chapter XX External causes of morbidity and mortality	0.987	0.013
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.986	0.014
C79 Secondary malignant neoplasm of other sites	0.986	0.014
Chapter X Diseases of the respiratory system	0.984	0.016
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.982	0.018
N40 Hyperplasia of prostate	0.979	0.021
R18 Ascites	0.978	0.022
R50-R69 General symptoms and signs	0.973	0.027
R50 Fever of unknown origin	0.968	0.032
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.968	0.032
R14 Flatulence and related conditions	0.967	0.033
R50.9 Fever, unspecified	0.963	0.037
Chapter XI Diseases of the digestive system	0.963	0.037
Chapter I Certain infectious and parasitic diseases	0.960	0.040
R94 Abnormal results of function studies	0.960	0.040
J20-J22 Other acute lower respiratory infections	0.955	0.045
R15 Faecal incontinence	0.954	0.046
Chapter VI Diseases of the nervous system	0.953	0.047
R94.5 Abnormal results of liver function studies	0.949	0.051
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.946	0.054
N30-N39 Other diseases of urinary system	0.939	0.061
I12 Hypertensive renal disease	0.938	0.062
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.937	0.063
C79.8 Secondary malignant neoplasm of other specified sites	0.935	0.065
C77.3 Axillary and upper limb lymph nodes	0.933	0.067
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.932	0.068
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.932	0.068
J22 Unspecified acute lower respiratory infection	0.931	0.069
N50 Other disorders of male genital organs	0.929	0.071
A30-A49 Other bacterial diseases	0.928	0.072
K50-K52 Noninfective enteritis and colitis	0.928	0.072
I70-I79 Diseases of arteries, arterioles and capillaries	0.927	0.072
J00-J06 Acute upper respiratory infections	0.926	0.074
N32 Other disorders of bladder	0.926	0.074
E20-E35 Disorders of other endocrine glands	0.918	0.082
G62 Other polyneuropathies	0.917	0.083
K52 Other non-infective gastro-enteritis and colitis	0.916	0.084
T81 Complications of procedures, not elsewhere classified	0.914	0.086
Chapter VIII Diseases of the ear and mastoid process	0.913	0.087
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.905	0.095
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.903	0.097
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.903	0.097
D50-D53 Nutritional anaemias	0.900	0.100
T84.0 Mechanical complication of internal joint prosthesis	0.899	0.101
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.899	0.101
J60-J70 Lung diseases due to external agents	0.898	0.102
E70-E90 Metabolic disorders	0.897	0.103
C50.1 Central portion of breast	0.896	0.104
A41 Other septicaemia	0.894	0.106
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.894	0.106
N32.0 Bladder-neck obstruction	0.892	0.108
K70-K77 Diseases of liver	0.892	0.108
E50-E64 Other nutritional deficiencies	0.891	0.109
N41 Inflammatory diseases of prostate	0.891	0.109
I12.9 Hypertensive renal disease without renal failure	0.889	0.111
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.888	0.112
N43 Hydrocele and spermatocele	0.884	0.116
R53 Malaise and fatigue	0.884	0.116
R91 Abnormal findings on diagnostic imaging of lung	0.880	0.120
G62.9 Polyneuropathy, unspecified	0.879	0.121
W00-W19 Falls	0.867	0.133
C50.5 Lower-outer quadrant of breast	0.867	0.133
N50.8 Other specified disorders of male genital organs	0.864	0.136
R79 Other abnormal findings of blood chemistry	0.864	0.136
C50.3 Lower-inner quadrant of breast	0.864	0.136
I71 Aortic aneurysm and dissection	0.863	0.137
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.861	0.139
N10-N16 Renal tubulo-interstitial diseases	0.859	0.141
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.859	0.141
A41.9 Septicaemia, unspecified	0.857	0.143
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.855	0.145
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.855	0.145
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.855	0.145
T81.4 Infection following a procedure, not elsewhere classified	0.854	0.146
K12 Stomatitis and related lesions	0.854	0.146
E00-E07 Disorders of thyroid gland	0.853	0.147
H90-H95 Other disorders of ear	0.853	0.147
D50 Iron deficiency anaemia	0.853	0.147
I95-I99 Other and unspecified disorders of the circulatory system	0.853	0.147
J02 Acute pharyngitis	0.853	0.147
C77.5 Intrapelvic lymph nodes	0.849	0.151
T66-T78 Other and unspecified effects of external causes	0.847	0.153
R63 Symptoms and signs concerning food and fluid intake	0.844	0.156
E87 Other disorders of fluid, electrolyte and acid-base balance	0.844	0.156
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.841	0.159
G62.8 Other specified polyneuropathies	0.841	0.159
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.841	0.159
N00-N08 Glomerular diseases	0.841	0.159
D50.9 Iron deficiency anaemia, unspecified	0.839	0.161
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.839	0.161
R79.8 Other specified abnormal findings of blood chemistry	0.834	0.166
N32.8 Other specified disorders of bladder	0.834	0.166
J69 Pneumonitis due to solids and liquids	0.833	0.167
N41.1 Chronic prostatitis	0.831	0.169
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.831	0.169
T83.0 Mechanical complication of urinary (indwelling) catheter	0.830	0.170
T88 Other complications of surgical and medical care, not elsewhere classified	0.829	0.170
C51-C58 Malignant neoplasms of female genital organs	0.827	0.173
K11 Diseases of salivary glands	0.827	0.173
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.826	0.174
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.825	0.175
S40-S49 Injuries to the shoulder and upper arm	0.820	0.180
R12 Heartburn	0.820	0.180
J90-J94 Other diseases of pleura	0.819	0.181
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.819	0.181
Y83.6 Removal of other organ (partial) (total)	0.819	0.181
R47-R49 Symptoms and signs involving speech and voice	0.817	0.183
S10-S19 Injuries to the neck	0.817	0.183
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.816	0.184
E22 Hyperfunction of pituitary gland	0.815	0.185
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.814	0.186
K55-K64 Other diseases of intestines	0.813	0.187
C80 Malignant neoplasm without specification of site	0.813	0.187
C77.8 Lymph nodes of multiple regions	0.809	0.190
S90-S99 Injuries to the ankle and foot	0.805	0.195
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.804	0.196
N43.3 Hydrocele, unspecified	0.803	0.197
J02.9 Acute pharyngitis, unspecified	0.800	0.200
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.799	0.201
N36 Other disorders of urethra	0.799	0.201
C15-C26 Malignant neoplasms of digestive organs	0.796	0.204
K08 Other disorders of teeth and supporting structures	0.796	0.204
K76 Other diseases of liver	0.794	0.205
C79.9 Secondary malignant neoplasm, unspecified site	0.794	0.206
W50-W64 Exposure to animate mechanical forces	0.793	0.207
I15 Secondary hypertension	0.792	0.208
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.791	0.209
H91 Other hearing loss	0.789	0.211
J69.0 Pneumonitis due to food and vomit	0.786	0.214
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.786	0.214
V40-V49 Car occupant injured in transport accident	0.784	0.216
K10 Other diseases of jaws	0.783	0.217
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.783	0.217
N17-N19 Renal failure	0.780	0.220
E34 Other endocrine disorders	0.779	0.221
D80-D89 Certain disorders involving the immune mechanism	0.778	0.222
R50.0 Fever with chills	0.778	0.222
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.778	0.222
G50-G59 Nerve, nerve root and plexus disorders	0.778	0.222
T20-T25 Burns and corrosions of external body surface, specified by site	0.777	0.223
E87.1 Hypo-osmolality and hyponatraemia	0.776	0.224
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.776	0.224
Y83.3 Surgical operation with formation of external stoma	0.775	0.225
K12.1 Other forms of stomatitis	0.775	0.225
N70-N77 Inflammatory diseases of female pelvic organs	0.774	0.226
J95-J99 Other diseases of the respiratory system	0.774	0.226
S20-S29 Injuries to the thorax	0.771	0.229
R63.0 Anorexia	0.770	0.230
K07 Dentofacial anomalies [including malocclusion]	0.770	0.230
C20 Malignant neoplasm of rectum	0.769	0.231
R90 Abnormal findings on diagnostic imaging of central nervous system	0.769	0.231
D37-D48 Neoplasms of uncertain or unknown behaviour	0.769	0.231
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.765	0.235
N05 Unspecified nephritic syndrome	0.765	0.235
I73 Other peripheral vascular diseases	0.765	0.235
T86 Failure and rejection of transplanted organs and tissues	0.763	0.237
E65-E68 Obesity and other hyperalimentation	0.763	0.237
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.763	0.237
N99-N99 Other disorders of the genitourinary system	0.762	0.238
E40-E46 Malnutrition	0.762	0.238
K76.0 Fatty (change of) liver, not elsewhere classified	0.761	0.239
C50.8 Overlapping lesion of breast	0.760	0.239
T84.1 Mechanical complication of internal fixation device of bones of limb	0.760	0.240
E04 Other non-toxic goitre	0.760	0.240
G70-G73 Diseases of myoneural junction and muscle	0.759	0.241
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.758	0.242
S50-S59 Injuries to the elbow and forearm	0.757	0.242
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.757	0.243
C83 Diffuse non-Hodgkin's lymphoma	0.757	0.243
B35-B49 Mycoses	0.756	0.244
A41.5 Septicaemia due to other Gram-negative organisms	0.755	0.245
B25-B34 Other viral diseases	0.754	0.246
R60 Oedema, not elsewhere classified	0.754	0.246
K52.3 Indeterminate colitis	0.753	0.247
D51 Vitamin B12 deficiency anaemia	0.752	0.247
E80 Disorders of porphyrin and bilirubin metabolism	0.750	0.250
V80-V89 Other land transport accidents	0.749	0.251
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.749	0.251
J00 Acute nasopharyngitis [common cold]	0.749	0.251
H80-H83 Diseases of inner ear	0.747	0.253
X60-X84 Intentional self-harm	0.747	0.253
K59 Other functional intestinal disorders	0.745	0.255
H91.9 Hearing loss, unspecified	0.743	0.257
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.742	0.258
C77.1 Intrathoracic lymph nodes	0.742	0.258
E87.2 Acidosis	0.741	0.259
X40-X49 Accidental poisoning by and exposure to noxious substances	0.741	0.259
I70 Atherosclerosis	0.740	0.260
C56 Malignant neoplasm of ovary	0.739	0.261
I95 Hypotension	0.739	0.261
E55 Vitamin D deficiency	0.739	0.261
N32.3 Diverticulum of bladder	0.737	0.263
T79-T79 Certain early complications of trauma	0.737	0.263
R51 Headache	0.733	0.267
T80 Complications following infusion, transfusion and therapeutic injection	0.733	0.267
N42 Other disorders of prostate	0.733	0.267
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.733	0.267
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.732	0.267
T81.3 Disruption of operation wound, not elsewhere classified	0.732	0.268
R87 Abnormal findings in specimens from female genital organs	0.732	0.268
N50.1 Vascular disorders of male genital organs	0.732	0.268
I05-I09 Chronic rheumatic heart diseases	0.731	0.269
K55 Vascular disorders of intestine	0.727	0.273
C34 Malignant neoplasm of bronchus and lung	0.727	0.273
R49 Voice disturbances	0.727	0.273
R68 Other general symptoms and signs	0.726	0.274
G80-G83 Cerebral palsy and other paralytic syndromes	0.725	0.274
J20 Acute bronchitis	0.725	0.275
S70-S79 Injuries to the hip and thigh	0.724	0.276
W20-W49 Exposure to inanimate mechanical forces	0.724	0.276
B99-B99 Other infectious diseases	0.723	0.277
T78 Adverse effects, not elsewhere classified	0.723	0.277
J93 Pneumothorax	0.723	0.277
Chapter XXII Codes for special purposes	0.722	0.278
C64-C68 Malignant neoplasms of urinary tract	0.722	0.278
E61 Deficiency of other nutrient elements	0.720	0.280
I73.9 Peripheral vascular disease, unspecified	0.719	0.281
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.718	0.282
R25 Abnormal involuntary movements	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
I13 Hypertensive heart and renal disease	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
C76 Malignant neoplasm of other and ill-defined sites	0.717	0.283
T87 Complications peculiar to reattachment and amputation	0.716	0.283
I11 Hypertensive heart disease	0.715	0.285
N51 Disorders of male genital organs in diseases classified elsewhere	0.715	0.285
N46 Male infertility	0.715	0.285
N44 Torsion of testis	0.715	0.285
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.715	0.285
E53 Deficiency of other B group vitamins	0.714	0.286
C50.6 Axillary tail of breast	0.714	0.286
C50.0 Nipple and areola	0.714	0.286
A46 Erysipelas	0.714	0.286
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.714	0.286
Chapter XV Pregnancy, childbirth and the puerperium	0.714	0.286
I72 Other aneurysm	0.713	0.287
G60 Hereditary and idiopathic neuropathy	0.713	0.287
E24 Cushing's syndrome	0.713	0.287
G61 Inflammatory polyneuropathy	0.712	0.288
N75 Diseases of Bartholin's gland	0.710	0.290
R10 Abdominal and pelvic pain	0.710	0.290
R16.0 Hepatomegaly, not elsewhere classified	0.710	0.290
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.708	0.292
Y35-Y36 Legal intervention and operations of war	0.708	0.292
Y10-Y34 Event of undetermined intent	0.708	0.292
Y00-Y09 Assault	0.708	0.292
X85-X99 Assault	0.708	0.292
X58-X59 Accidental exposure to other and unspecified factors	0.708	0.292
X50-X57 Overexertion, travel and privation	0.708	0.292
X30-X39 Exposure to forces of nature	0.708	0.292
X20-X29 Contact with venomous animals and plants	0.708	0.292
X10-X19 Contact with heat and hot substances	0.708	0.292
X00-X09 Exposure to smoke, fire and flames	0.708	0.292
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.708	0.292
W75-W84 Other accidental threats to breathing	0.708	0.292
W65-W74 Accidental drowning and submersion	0.708	0.292
V98-V99 Other and unspecified transport accidents	0.708	0.292
V95-V97 Air and space transport accidents	0.708	0.292
V90-V94 Water transport accidents	0.708	0.292
V70-V79 Bus occupant injured in transport accident	0.708	0.292
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.708	0.292
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.708	0.292
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.708	0.292
V01-V09 Pedestrian injured in transport accident	0.708	0.292
B90-B94 Sequelae of infectious and parasitic diseases	0.708	0.292
T15-T19 Effects of foreign body entering through natural orifice	0.707	0.293
V20-V29 Motorcycle rider injured in transport accident	0.707	0.293
T84.3 Mechanical complication of other bone devices, implants and grafts	0.707	0.293
C79.6 Secondary malignant neoplasm of ovary	0.707	0.293
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.707	0.293
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.707	0.293
A49 Bacterial infection of unspecified site	0.707	0.293
T92 Sequelae of injuries of upper limb	0.706	0.294
K60 Fissure and fistula of anal and rectal regions	0.706	0.294
C91 Lymphoid leukaemia	0.706	0.294
B02 Zoster [herpes zoster]	0.705	0.295
C78.1 Secondary malignant neoplasm of mediastinum	0.704	0.295
E06 Thyroiditis	0.704	0.295
R92 Abnormal findings on diagnostic imaging of breast	0.704	0.296
K08.8 Other specified disorders of teeth and supporting structures	0.704	0.296
E28 Ovarian dysfunction	0.703	0.297
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.703	0.297
R50.8 Other specified fever	0.702	0.298
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.701	0.299
I12.0 Hypertensive renal disease with renal failure	0.698	0.302
K59.0 Constipation	0.698	0.302
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.697	0.302
R62 Lack of expected normal physiological development	0.697	0.302
R57 Shock, not elsewhere classified	0.697	0.302
R64 Cachexia	0.697	0.302
R58 Haemorrhage, not elsewhere classified	0.697	0.302
R79.9 Abnormal finding of blood chemistry, unspecified	0.696	0.304
J04 Acute laryngitis and tracheitis	0.696	0.304
R23 Other skin changes	0.695	0.305
K72 Hepatic failure, not elsewhere classified	0.695	0.305
N10 Acute tubulo-interstitial nephritis	0.694	0.306
R50.2 Drug-induced fever	0.694	0.306
R50.1 Persistent fever	0.694	0.306
K56 Paralytic ileus and intestinal obstruction without hernia	0.694	0.306
T85 Complications of other internal prosthetic devices, implants and grafts	0.694	0.306
G00-G09 Inflammatory diseases of the central nervous system	0.694	0.306
C77.4 Inguinal and lower limb lymph nodes	0.694	0.306
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.693	0.307
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.693	0.307
B07 Viral warts	0.693	0.307
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.692	0.307
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.692	0.308
K00 Disorders of tooth development and eruption	0.692	0.308
W08 Fall involving other furniture	0.691	0.309
H92 Otalgia and effusion of ear	0.691	0.309
K01 Embedded and impacted teeth	0.690	0.310
N13 Obstructive and reflux uropathy	0.688	0.312
B85-B89 Pediculosis, acariasis and other infestations	0.688	0.312
B65-B83 Helminthiases	0.688	0.312
B50-B64 Protozoal diseases	0.688	0.312
B20-B24 Human immunodeficiency virus [HIV] disease	0.688	0.312
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.688	0.312
A75-A79 Rickettsioses	0.688	0.312
A70-A74 Other diseases caused by chlamydiae	0.688	0.312
A65-A69 Other spirochaetal diseases	0.688	0.312
A20-A28 Certain zoonotic bacterial diseases	0.688	0.312
A15-A19 Tuberculosis	0.688	0.312
R94.8 Abnormal results of function studies of other organs and systems	0.688	0.312
R94.7 Abnormal results of other endocrine function studies	0.688	0.312
R94.6 Abnormal results of thyroid function studies	0.688	0.312
R94.2 Abnormal results of pulmonary function studies	0.688	0.312
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.688	0.312
R94.0 Abnormal results of function studies of central nervous system	0.688	0.312
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.688	0.312
R94.4 Abnormal results of kidney function studies	0.686	0.314
N19 Unspecified renal failure	0.686	0.314
R63.5 Abnormal weight gain	0.686	0.314
H60-H62 Diseases of external ear	0.686	0.314
R61 Hyperhidrosis	0.685	0.314
J21 Acute bronchiolitis	0.685	0.315
J01 Acute sinusitis	0.684	0.316
K74 Fibrosis and cirrhosis of liver	0.684	0.316
K13 Other diseases of lip and oral mucosa	0.682	0.318
T81.7 Vascular complications following a procedure, not elsewhere classified	0.682	0.318
C78.2 Secondary malignant neoplasm of pleura	0.681	0.319
W19 Unspecified fall	0.681	0.319
S30 Superficial injury of abdomen, lower back and pelvis	0.681	0.319
E34.9 Endocrine disorder, unspecified	0.680	0.320
C80.0 Malignant neoplasm, primary site unknown, so stated	0.679	0.321
A80-A89 Viral infections of the central nervous system	0.679	0.321
N11 Chronic tubulo-interstitial nephritis	0.678	0.321
G90-G99 Other disorders of the nervous system	0.678	0.322
E88 Other metabolic disorders	0.676	0.323
R10.3 Pain localised to other parts of lower abdomen	0.676	0.324
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.676	0.324
W18 Other fall on same level	0.675	0.324
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.674	0.326
N37 Urethral disorders in diseases classified elsewhere	0.673	0.326
N34 Urethritis and urethral syndrome	0.673	0.326
N33 Bladder disorders in diseases classified elsewhere	0.673	0.326
C32 Malignant neoplasm of larynx	0.673	0.327
K06 Other disorders of gingiva and edentulous alveolar ridge	0.673	0.327
Y60-Y69 Misadventures to patients during surgical and medical care	0.673	0.327
C34.9 Bronchus or lung, unspecified	0.673	0.327
N41.0 Acute prostatitis	0.672	0.327
D55-D59 Haemolytic anaemias	0.672	0.328
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.672	0.328
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.671	0.328
Y83.1 Surgical operation with implant of artificial internal device	0.671	0.329
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.670	0.330
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.670	0.330
W13 Fall from, out of or through building or structure	0.669	0.331
K70 Alcoholic liver disease	0.669	0.331
G64 Other disorders of peripheral nervous system	0.669	0.331
K03 Other diseases of hard tissues of teeth	0.668	0.331
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.668	0.332
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.668	0.332
K65-K67 Diseases of peritoneum	0.667	0.333
N50.9 Disorder of male genital organs, unspecified	0.666	0.334
N50.0 Atrophy of testis	0.666	0.334
I77 Other disorders of arteries and arterioles	0.665	0.334
A48 Other bacterial diseases, not elsewhere classified	0.665	0.335
A44 Bartonellosis	0.665	0.335
A43 Nocardiosis	0.665	0.335
A42 Actinomycosis	0.665	0.335
A40 Streptococcal septicaemia	0.665	0.335
A39 Meningococcal infection	0.665	0.335
A37 Whooping cough	0.665	0.335
A36 Diphtheria	0.665	0.335
A32 Listeriosis	0.665	0.335
A31 Infection due to other mycobacteria	0.665	0.335
A30 Leprosy [Hansen's disease]	0.665	0.335
A38 Scarlet fever	0.665	0.335
A35 Other tetanus	0.665	0.335
A34 Obstetrical tetanus	0.665	0.335
A33 Tetanus neonatorum	0.665	0.335
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.665	0.335
N75.0 Cyst of Bartholin's gland	0.664	0.336
N32.4 Rupture of bladder, nontraumatic	0.664	0.336
N32.2 Vesical fistula, not elsewhere classified	0.664	0.336
K60.3 Anal fistula	0.664	0.336
K52.1 Toxic gastro-enteritis and colitis	0.663	0.337
E27 Other disorders of adrenal gland	0.663	0.337
C90 Multiple myeloma and malignant plasma cell neoplasms	0.663	0.337
E87.0 Hyperosmolality and hypernatraemia	0.662	0.338
E29 Testicular dysfunction	0.662	0.338
K11.8 Other diseases of salivary glands	0.661	0.339
K12.3 Oral mucositis (ulcerative)	0.660	0.340
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.660	0.340
G57 Mononeuropathies of lower limb	0.659	0.341
E05 Thyrotoxicosis [hyperthyroidism]	0.659	0.341
S49 Other and unspecified injuries of shoulder and upper arm	0.659	0.341
K09 Cysts of oral region, not elsewhere classified	0.658	0.341
E35 Disorders of endocrine glands in diseases classified elsewhere	0.658	0.342
E32 Diseases of thymus	0.658	0.342
E31 Polyglandular dysfunction	0.658	0.342
E30 Disorders of puberty, not elsewhere classified	0.658	0.342
E26 Hyperaldosteronism	0.658	0.342
E25 Adrenogenital disorders	0.658	0.342
E20 Hypoparathyroidism	0.658	0.342
K75 Other inflammatory liver diseases	0.658	0.342
T88.4 Failed or difficult intubation	0.658	0.342
G62.2 Polyneuropathy due to other toxic agents	0.658	0.342
G62.1 Alcoholic polyneuropathy	0.658	0.342
G62.0 Drug-induced polyneuropathy	0.658	0.342
A50-A64 Infections with a predominantly sexual mode of transmission	0.657	0.342
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.657	0.343
K52.0 Gastro-enteritis and colitis due to radiation	0.657	0.343
K76.6 Portal hypertension	0.656	0.344
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.656	0.344
T81.9 Unspecified complication of procedure	0.655	0.345
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.655	0.345
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.655	0.345
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.655	0.345
C17 Malignant neoplasm of small intestine	0.655	0.345
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.655	0.345
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.655	0.345
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.654	0.345
C83.3 Large cell (diffuse)	0.654	0.346
N08 Glomerular disorders in diseases classified elsewhere	0.654	0.346
K11.5 Sialolithiasis	0.653	0.347
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.653	0.347
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.653	0.347
N32.9 Bladder disorder, unspecified	0.653	0.347
S99 Other and unspecified injuries of ankle and foot	0.653	0.347
N05.8 Other	0.651	0.349
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.650	0.350
K35-K38 Diseases of appendix	0.650	0.350
I71.3 Abdominal aortic aneurysm, ruptured	0.649	0.351
K55.0 Acute vascular disorders of intestine	0.648	0.352
C78.4 Secondary malignant neoplasm of small intestine	0.647	0.353
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.647	0.353
K07.6 Temporomandibular joint disorders	0.647	0.353
C79.7 Secondary malignant neoplasm of adrenal gland	0.647	0.353
R60.0 Localised oedema	0.646	0.354
D86 Sarcoidosis	0.646	0.354
D53 Other nutritional anaemias	0.645	0.355
D52 Folate deficiency anaemia	0.645	0.355
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.645	0.355
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.645	0.355
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.645	0.355
T83.2 Mechanical complication of graft of urinary organ	0.645	0.355
T83.1 Mechanical complication of other urinary devices and implants	0.645	0.355
W07 Fall involving chair	0.645	0.355
H90 Conductive and sensorineural hearing loss	0.645	0.355
Y95 Nosocomial condition	0.645	0.355
E80.4 Gilbert's syndrome	0.645	0.355
E87.7 Fluid overload	0.644	0.356
K11.2 Sialoadenitis	0.644	0.356
I15.1 Hypertension secondary to other renal disorders	0.644	0.356
G30-G32 Other degenerative diseases of the nervous system	0.644	0.356
J70 Respiratory conditions due to other external agents	0.644	0.356
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.644	0.356
J67 Hypersensitivity pneumonitis due to organic dust	0.644	0.356
J66 Airway disease due to specific organic dust	0.644	0.356
J63 Pneumoconiosis due to other inorganic dusts	0.644	0.356
J62 Pneumoconiosis due to dust containing silica	0.644	0.356
J65 Pneumoconiosis associated with tuberculosis	0.644	0.356
J64 Unspecified pneumoconiosis	0.644	0.356
J60 Coalworker's pneumoconiosis	0.644	0.356
E85 Amyloidosis	0.643	0.357
E84 Cystic fibrosis	0.643	0.357

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations