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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78371551
log Bayes Factor = 5.54553
Chromosome 2   position 12,631,328  (GRCh37) Explore rs78371551 on Ensembl!
Variant rs78371551 is part of Cluster X0101

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
M54 Dorsalgia
0.998 0.002 0.000
M15-M19 Arthrosis
0.993 0.007 0.000
M54.3 Sciatica
0.992 0.008 0.000
M17 Gonarthrosis [arthrosis of knee]
0.989 0.011 0.000
M54.39 Sciatica (Site unspecified)
0.982 0.018 0.000
M20-M25 Other joint disorders
0.975 0.025 0.000
M05-M14 Inflammatory polyarthropathies
0.972 0.028 0.000
M17.9 Gonarthrosis, unspecified
0.972 0.028 0.000
M20 Acquired deformities of fingers and toes
0.972 0.028 0.000
M17.0 Primary gonarthrosis, bilateral
0.962 0.038 0.000
M20.4 Other hammer toe(s) (acquired)
0.957 0.043 0.000
M50 Cervical disk disorders
0.949 0.051 0.000
M05 Seropositive rheumatoid arthritis
0.945 0.055 0.000
M70-M79 Other soft tissue disorders
0.943 0.057 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.931 0.069 0.000
M80-M85 Disorders of bone density and structure
0.927 0.073 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.925 0.075 0.000
M79.6 Pain in limb
0.924 0.076 0.000
M24 Other specific joint derangements
0.923 0.077 0.000
M65-M68 Disorders of synovium and tendon
0.915 0.085 0.000
M50.0 Cervical disk disorder with myelopathy
0.905 0.095 0.000
M54.2 Cervicalgia
0.904 0.096 0.000
M40-M43 Deforming dorsopathies
0.893 0.107 0.000
M79.66 Pain in limb (Lower leg)
0.889 0.111 0.000
M20.3 Other deformity of hallux (acquired)
0.874 0.126 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.870 0.130 0.000
M79.62 Pain in limb (Upper arm)
0.866 0.134 0.000
M54.9 Dorsalgia, unspecified
0.856 0.144 0.000
M16 Coxarthrosis [arthrosis of hip]
0.855 0.145 0.000
M65 Synovitis and tenosynovitis
0.847 0.153 0.000
M79.61 Pain in limb (Shoulder region)
0.843 0.157 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.838 0.162 0.000
M13 Other arthritis
0.835 0.165 0.000
M50.1 Cervical disk disorder with radiculopathy
0.834 0.166 0.000
M54.36 Sciatica (Lumbar region)
0.832 0.168 0.000
M17.5 Other secondary gonarthrosis
0.832 0.168 0.000
M20.1 Hallux valgus (acquired)
0.832 0.168 0.000
M00-M03 Infectious arthropathies
0.830 0.170 0.000
M15 Polyarthrosis
0.829 0.171 0.000
M54.8 Other dorsalgia
0.820 0.180 0.000
M84 Disorders of continuity of bone
0.819 0.181 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.816 0.184 0.000
M77 Other enthesopathies
0.809 0.191 0.000
M54.29 Cervicalgia-Site unspe
0.809 0.191 0.000
M81 Osteoporosis without pathological fracture
0.804 0.196 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.802 0.198 0.000
M16.0 Primary coxarthrosis, bilateral
0.796 0.204 0.000
M79.1 Myalgia
0.787 0.213 0.000
M91-M94 Chondropathies
0.785 0.215 0.000
M16.7 Other secondary coxarthrosis
0.783 0.217 0.000
M53 Other dorsopathies, not elsewhere classified
0.783 0.217 0.000
M79.5 Residual foreign body in soft tissue
0.778 0.222 0.000
M07 Psoriatic and enteropathic arthropathies
0.778 0.222 0.000
M66 Spontaneous rupture of synovium and tendon
0.776 0.224 0.000
M85 Other disorders of bone density and structure
0.776 0.224 0.000
M79.60 Pain in limb (Multiple sites)
0.771 0.229 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.769 0.231 0.000
M24.2 Disorder of ligament
0.768 0.232 0.000
M12 Other specific arthropathies
0.765 0.235 0.000
M60-M63 Disorders of muscles
0.764 0.236 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.762 0.238 0.000
M54.37 Sciatica (Lumbosacral region)
0.761 0.239 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.758 0.242 0.000
M86-M90 Other osteopathies
0.758 0.242 0.000
M54.4 Lumbago with sciatica
0.756 0.244 0.000
M41 Scoliosis
0.753 0.247 0.000
M24.5 Contracture of joint
0.751 0.249 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.741 0.259 0.000
M77.9 Enthesopathy, unspecified
0.737 0.263 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.735 0.265 0.000
M54.6 Pain in thoracic spine
0.735 0.265 0.000
M40 Kyphosis and lordosis
0.732 0.268 0.000
M71 Other bursopathies
0.727 0.273 0.000
M13.9 Arthritis, unspecified
0.727 0.273 0.000
M79.67 Pain in limb (Ankle and foot)
0.726 0.274 0.000
M54.22 Cervicalgia (Cervical region)
0.724 0.276 0.000
M54.0 Panniculitis affecting regions of neck and back
0.716 0.284 0.000
M84.0 Malunion of fracture
0.715 0.285 0.000
M24.6 Ankylosis of joint
0.713 0.287 0.000
M54.35 Sciatica (Thoracolumbar region)
0.711 0.289 0.000
M54.34 Sciatica-Thoracic
0.711 0.289 0.000
M54.33 Sciatica-Cervicothoracic
0.711 0.289 0.000
M54.32 Sciatica-Cervical
0.711 0.289 0.000
M54.31 Sciatica-Occipit-atl-axl
0.711 0.289 0.000
M54.30 Sciatica (Multiple sites in spine)
0.711 0.289 0.000
M20.5 Other deformities of toe(s) (acquired)
0.711 0.289 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.709 0.291 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.709 0.291 0.000
M65.8 Other synovitis and tenosynovitis
0.709 0.291 0.000
M65.3 Trigger finger
0.704 0.296 0.000
M50.3 Other cervical disk degeneration
0.703 0.297 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.699 0.301 0.000
M32 Systemic lupus erythematosus
0.699 0.301 0.000
M24.0 Loose body in joint
0.699 0.301 0.000
M77.4 Metatarsalgia
0.698 0.302 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.697 0.303 0.000
M08 Juvenile arthritis
0.697 0.303 0.000
M24.7 Protrusio acetabuli
0.697 0.303 0.000
M54.1 Radiculopathy
0.697 0.303 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.694 0.306 0.000
M54.86 Other dorsalgia (Lumbar region)
0.693 0.307 0.000
M33 Dermatopolymyositis
0.693 0.307 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.690 0.310 0.000
M21 Other acquired deformities of limbs
0.690 0.310 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.689 0.311 0.000
M17.3 Other posttraumatic gonarthrosis
0.688 0.312 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.683 0.317 0.000
M00 Pyogenic arthritis
0.681 0.319 0.000
M50.8 Other cervical disk disorders
0.680 0.320 0.000
M05.8 Other seropositive rheumatoid arthritis
0.677 0.323 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.677 0.323 0.000
M05.2 Rheumatoid vasculitis
0.677 0.323 0.000
M05.1 Rheumatoid lung disease
0.677 0.323 0.000
M05.0 Felty's syndrome
0.677 0.323 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.677 0.323 0.000
M43 Other deforming dorsopathies
0.677 0.323 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.676 0.323 0.000
M30 Polyarteritis nodosa and related conditions
0.674 0.326 0.000
M45-M49 Spondylopathies
0.674 0.326 0.000
M81.9 Osteoporosis, unspecified
0.673 0.327 0.000
M79.10 Myalgia (Multiple sites)
0.673 0.327 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.671 0.329 0.000
M79.9 Soft tissue disorder, unspecified
0.668 0.332 0.000
M79.3 Panniculitis, unspecified
0.668 0.332 0.000
M83 Adult osteomalacia
0.664 0.336 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.663 0.337 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.663 0.337 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.663 0.337 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.663 0.337 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.663 0.337 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.663 0.337 0.000
M79.68 Pain in limb (Other)
0.663 0.337 0.000
M41.9 Scoliosis, unspecified
0.662 0.338 0.000
M24.9 Joint derangement, unspecified
0.662 0.338 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.662 0.338 0.000
M14 Arthropathies in other diseases classified elsewhere
0.661 0.339 0.000
M11 Other crystal arthropathies
0.658 0.341 0.000
M79.19 Myalgia (Site unspecified)
0.657 0.343 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.656 0.344 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.655 0.345 0.000
M66.2 Spontaneous rupture of extensor tendons
0.654 0.346 0.000
M81.2 Osteoporosis of disuse
0.654 0.346 0.000
M13.8 Other specified arthritis
0.652 0.348 0.000
M76 Enthesopathies of lower limb, excluding foot
0.651 0.349 0.000
M79.7 Fibromyalgia
0.651 0.349 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.648 0.351 0.000
M54.27 Cervicalgia-Lumbosacral
0.648 0.351 0.000
M54.26 Cervicalgia-Lumbar
0.648 0.351 0.000
M54.25 Cervicalgia-Thoracolumbar
0.648 0.351 0.000
M54.24 Cervicalgia-Thoracic
0.648 0.351 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.648 0.351 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.648 0.351 0.000
M54.20 Cervicalgia-Mult site
0.648 0.351 0.000
M50.9 Cervical disk disorder, unspecified
0.645 0.354 0.000
M10 Gout
0.643 0.357 0.000
M15.8 Other polyarthrosis
0.642 0.358 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.641 0.359 0.000
M42 Spinal osteochondrosis
0.640 0.359 0.000
M02 Reactive arthropathies
0.640 0.360 0.000
M46 Other inflammatory spondylopathies
0.640 0.360 0.000
M60 Myositis
0.639 0.360 0.000
M07.3 Other psoriatic arthropathies
0.638 0.362 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.637 0.363 0.000
M20.2 Hallux rigidus
0.634 0.366 0.000
M34 Systemic sclerosis
0.632 0.368 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.632 0.368 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.630 0.370 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.627 0.373 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.627 0.373 0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)
0.626 0.373 0.000
M35 Other systemic involvement of connective tissue
0.626 0.374 0.000
M79.69 Pain in limb (Site unspecified)
0.625 0.374 0.000
M16.5 Other posttraumatic coxarthrosis
0.625 0.374 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.623 0.377 0.000
M79.11 Myalgia (Shoulder region)
0.621 0.379 0.000
M77.92 Enthesopathy, unspecified (Upper arm)
0.621 0.379 0.000
M92 Other juvenile osteochondrosis
0.621 0.379 0.000
M90 Osteopathies in diseases classified elsewhere
0.620 0.380 0.000
M77.47 Metatarsalgia-Ankle/Foot
0.619 0.381 0.000
M94 Other disorders of cartilage
0.618 0.382 0.000
M24.28 Disorder of ligament (Other)
0.618 0.382 0.000
M65.1 Other infective (teno)synovitis
0.617 0.383 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.617 0.383 0.000
M24.24 Disorder of ligament (Hand)
0.615 0.385 0.000
M51 Other intervertebral disk disorders
0.615 0.385 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.614 0.386 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.614 0.386 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.614 0.386 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.614 0.386 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.613 0.387 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.613 0.387 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.613 0.387 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.613 0.387 0.000
M85.0 Fibrous dysplasia (monostotic)
0.612 0.388 0.000
M24.54 Contracture of joint (Hand)
0.609 0.391 0.000
M79.58 Residual foreign body in soft tissue (Other)
0.608 0.392 0.000
M84.4 Pathological fracture, not elsewhere classified
0.608 0.392 0.000
M65.2 Calcific tendinitis
0.607 0.393 0.000
M65.0 Abscess of tendon sheath
0.607 0.393 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.606 0.394 0.000
M79.0 Rheumatism, unspecified
0.605 0.395 0.000
M13.1 Monoarthritis, not elsewhere classified
0.605 0.395 0.000
M79.8 Other specified soft tissue disorders
0.605 0.395 0.000
M85.8 Other specified disorders of bone density and structure
0.603 0.396 0.000
M53.8 Other specified dorsopathies
0.603 0.397 0.000
M65.34 Trigger finger-Hand
0.602 0.398 0.000
M77.96 Enthesopathy, unspecified (Lower leg)
0.601 0.398 0.000
M12.3 Palindromic rheumatism
0.601 0.399 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.601 0.399 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.601 0.399 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.601 0.399 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.601 0.399 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.601 0.399 0.000
M77.94 Enthesopathy, unspecified (Hand)
0.601 0.399 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.599 0.401 0.000
M40.2 Other and unspecified kyphosis
0.599 0.401 0.000
M86 Osteomyelitis
0.598 0.402 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.598 0.402 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.595 0.404 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.595 0.404 0.000
M66.3 Spontaneous rupture of flexor tendons
0.594 0.405 0.000
M15.9 Polyarthrosis, unspecified
0.594 0.406 0.000
M15.0 Primary generalised (osteo)arthrosis
0.594 0.406 0.000
M15.4 Erosive (osteo)arthrosis
0.594 0.406 0.000
M15.3 Secondary multiple arthrosis
0.594 0.406 0.000
M79.15 Myalgia (Pelvic region and thigh)
0.593 0.407 0.000
M85.6 Other cyst of bone
0.592 0.408 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.592 0.408 0.000
M15.1 Heberden's nodes (with arthropathy)
0.591 0.409 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.591 0.409 0.000
M81.98 Osteoporosis, unspecified (Other)
0.591 0.409 0.000
M84.02 Malunion of fracture (Upper arm)
0.589 0.411 0.000
M71.0 Abscess of bursa
0.589 0.411 0.000
M65.83 Other synovitis and tenosynovitis (Forearm)
0.588 0.412 0.000
M54.89 Other dorsalgia (Site unspecified)
0.588 0.412 0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.588 0.412 0.000
M54.87 Other dorsalgia (Lumbosacral region)
0.588 0.412 0.000
M54.85 Other dorsalgia (Thoracolumbar region)
0.588 0.412 0.000
M54.84 Other dorsalgia (Thoracic region)
0.588 0.412 0.000
M54.83 Other dorsalgia (Cervicothoracic region)
0.588 0.412 0.000
M54.82 Other dorsalgia (Cervical region)
0.588 0.412 0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.588 0.412 0.000
M54.80 Other dorsalgia (Multiple sites in spine)
0.588 0.412 0.000
M84.9 Disorder of continuity of bone, unspecified
0.587 0.413 0.000
M84.8 Other disorders of continuity of bone
0.587 0.413 0.000
M84.3 Stress fracture, not elsewhere classified
0.587 0.413 0.000
M84.2 Delayed union of fracture
0.587 0.413 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.580 0.420 0.000
M77.3 Calcaneal spur
0.580 0.420 0.000
M77.2 Periarthritis of wrist
0.580 0.420 0.000
M20.0 Deformity of finger(s)
0.579 0.420 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.578 0.422 0.000
M24.23 Disorder of ligament (Forearm)
0.578 0.422 0.000
M24.57 Contracture of joint (Ankle and foot)
0.576 0.423 0.000
M81.8 Other osteoporosis
0.576 0.424 0.000
M81.6 Localised osteoporosis [Lequesne]
0.576 0.424 0.000
M81.5 Idiopathic osteoporosis
0.576 0.424 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.576 0.424 0.000
M81.1 Postoophorectomy osteoporosis
0.576 0.424 0.000
M81.0 Postmenopausal osteoporosis
0.576 0.424 0.000
M80 Osteoporosis with pathological fracture
0.576 0.424 0.000
M13.94 Arthritis, unspecified (Hand)
0.575 0.425 0.000
M00.9 Pyogenic arthritis, unspecified
0.573 0.427 0.000
M79.54 Residual foreign body in soft tissue (Hand)
0.572 0.428 0.000
M81.4 Drug-induced osteoporosis
0.572 0.428 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.572 0.428 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.571 0.429 0.000
M82 Osteoporosis in diseases classified elsewhere
0.569 0.430 0.000
M12.2 Villonodular synovitis (pigmented)
0.569 0.431 0.000
M54.5 Low back pain
0.569 0.431 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.569 0.431 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.568 0.432 0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)
0.567 0.433 0.000
M77.91 Enthesopathy, unspecified (Shoulder region)
0.566 0.434 0.000
M87 Osteonecrosis
0.566 0.434 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.565 0.435 0.000
M79.17 Myalgia (Ankle and foot)
0.564 0.436 0.000
M79.14 Myalgia (Hand)
0.564 0.436 0.000
M79.13 Myalgia (Forearm)
0.564 0.436 0.000
M79.12 Myalgia (Upper arm)
0.564 0.436 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.563 0.437 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.563 0.437 0.000
M53.9 Dorsopathy, unspecified
0.561 0.438 0.000
M53.2 Spinal instabilities
0.561 0.438 0.000
M53.1 Cervicobrachial syndrome
0.561 0.438 0.000
M53.0 Cervicocranial syndrome
0.561 0.438 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.561 0.439 0.000
M66.0 Rupture of popliteal cyst
0.560 0.439 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.560 0.440 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.559 0.441 0.000
M79.59 Residual foreign body in soft tissue (Site unspecified)
0.558 0.442 0.000
M79.56 Residual foreign body in soft tissue (Lower leg)
0.558 0.442 0.000
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)
0.558 0.442 0.000
M79.53 Residual foreign body in soft tissue (Forearm)
0.558 0.442 0.000
M79.52 Residual foreign body in soft tissue (Upper arm)
0.558 0.442 0.000
M79.51 Residual foreign body in soft tissue (Shoulder region)
0.558 0.442 0.000
M79.50 Residual foreign body in soft tissue (Multiple sites)
0.558 0.442 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.558 0.442 0.000
M07.6 Other enteropathic arthropathies
0.558 0.442 0.000
M07.5 Arthropathy in ulcerative colitis
0.558 0.442 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.558 0.442 0.000
M07.2 Psoriatic spondylitis
0.558 0.442 0.000
M07.1 Arthritis mutilans
0.558 0.442 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.558 0.442 0.000
M66.5 Spontaneous rupture of unspecified tendon
0.557 0.443 0.000
M66.4 Spontaneous rupture of other tendons
0.557 0.443 0.000
M66.1 Rupture of synovium
0.557 0.443 0.000
M85.9 Disorder of bone density and structure, unspecified
0.556 0.444 0.000
M85.5 Aneurysmal bone cyst
0.556 0.444 0.000
M85.4 Solitary bone cyst
0.556 0.444 0.000
M85.3 Osteitis condensans
0.556 0.444 0.000
M85.2 Hyperostosis of skull
0.556 0.444 0.000
M85.1 Skeletal fluorosis
0.556 0.444 0.000
M24.26 Disorder of ligament (Lower leg)
0.556 0.444 0.000
M22 Disorders of patella
0.555 0.445 0.000
M40.5 Lordosis, unspecified
0.552 0.448 0.000
M54.12 Radiculopathy (Cervical region)
0.552 0.448 0.000
M24.29 Disorder of ligament (Site unspecified)
0.551 0.449 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.551 0.449 0.000
M24.22 Disorder of ligament (Upper arm)
0.551 0.449 0.000
M24.20 Disorder of ligament (Multiple sites)
0.551 0.449 0.000
M60.0 Infective myositis
0.550 0.449 0.000
M13.0 Polyarthritis, unspecified
0.549 0.451 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.549 0.451 0.000
M12.5 Traumatic arthropathy
0.549 0.451 0.000
M12.4 Intermittent hydrarthrosis
0.549 0.451 0.000
M12.1 Kaschin-Beck disease
0.549 0.451 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.549 0.451 0.000
M84.03 Malunion of fracture (Forearm)
0.548 0.452 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.548 0.452 0.000
M61 Calcification and ossification of muscle
0.548 0.452 0.000
M81.20 Osteoporosis of disuse (Multiple sites)
0.546 0.454 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.546 0.454 0.000
M21.4 Flat foot [pes planus] (acquired)
0.545 0.455 0.000
M43.0 Spondylolysis
0.545 0.455 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.545 0.455 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.543 0.456 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.543 0.456 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.543 0.457 0.000
M24.21 Disorder of ligament (Shoulder region)
0.543 0.457 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.542 0.458 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.542 0.458 0.000
M54.44 Lumbago with sciatica-Thoracic
0.542 0.458 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.542 0.458 0.000
M54.42 Lumbago with sciatica-Cervical
0.542 0.458 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.542 0.458 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.542 0.458 0.000
M16.1 Other primary coxarthrosis
0.541 0.459 0.000
M54.57 Low back pain (Lumbosacral region)
0.540 0.460 0.000
M41.5 Other secondary scoliosis
0.540 0.460 0.000
M41.4 Neuromuscular scoliosis
0.540 0.460 0.000
M41.3 Thoracogenic scoliosis
0.540 0.460 0.000
M41.2 Other idiopathic scoliosis
0.540 0.460 0.000
M41.1 Juvenile idiopathic scoliosis
0.540 0.460 0.000
M41.0 Infantile idiopathic scoliosis
0.540 0.460 0.000
M24.03 Loose body in joint (Forearm)
0.539 0.461 0.000
M24.59 Contracture of joint (Site unspecified)
0.539 0.461 0.000
M24.58 Contracture of joint (Other)
0.539 0.461 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.539 0.461 0.000
M24.53 Contracture of joint (Forearm)
0.539 0.461 0.000
M24.52 Contracture of joint (Upper arm)
0.539 0.461 0.000
M24.51 Contracture of joint (Shoulder region)
0.539 0.461 0.000
M24.50 Contracture of joint (Multiple sites)
0.539 0.461 0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.537 0.462 0.000
M88 Paget's disease of bone [osteitis deformans]
0.535 0.464 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.535 0.465 0.000
M24.75 Protrusio acetabuli-Pelvic/thigh
0.535 0.465 0.000
M77.5 Other enthesopathy of foot
0.534 0.465 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.534 0.466 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.533 0.467 0.000
M84.04 Malunion of fracture (Hand)
0.531 0.468 0.000
M77.99 Enthesopathy, unspecified (Site unspecified)
0.528 0.472 0.000
M77.98 Enthesopathy, unspecified (Other)
0.528 0.472 0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)
0.528 0.472 0.000
M77.93 Enthesopathy, unspecified (Forearm)
0.528 0.472 0.000
M77.90 Enthesopathy, unspecified (Multiple sites)
0.528 0.472 0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)
0.528 0.472 0.000
M24.02 Loose body in joint (Upper arm)
0.528 0.472 0.000
M24.56 Contracture of joint (Lower leg)
0.528 0.472 0.000
M84.01 Malunion of fracture (Shoulder region)
0.527 0.473 0.000
M54.69 Pain in thoracic spine-Site unspe
0.527 0.473 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.527 0.473 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.527 0.473 0.000
M54.66 Pain in thoracic spine-Lumbar
0.527 0.473 0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.527 0.473 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.527 0.473 0.000
M54.62 Pain in thoracic spine-Cervical
0.527 0.473 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.527 0.473 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.527 0.473 0.000
M16.3 Other dysplastic coxarthrosis
0.527 0.473 0.000
M40.4 Other lordosis
0.525 0.475 0.000
M40.3 Flatback syndrome
0.525 0.475 0.000
M40.1 Other secondary kyphosis
0.525 0.475 0.000
M40.0 Postural kyphosis
0.525 0.475 0.000
M71.1 Other infective bursitis
0.523 0.477 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.522 0.478 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.521 0.479 0.000
M71.9 Bursopathy, unspecified
0.521 0.479 0.000
M71.8 Other specified bursopathies
0.521 0.479 0.000
M71.5 Other bursitis, not elsewhere classified
0.521 0.479 0.000
M71.4 Calcium deposit in bursa
0.521 0.479 0.000
M90.7 Fracture of bone in neoplastic disease
0.521 0.479 0.000
M92.6 Juvenile osteochondrosis of tarsus
0.519 0.481 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.518 0.482 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.517 0.482 0.000
M41.8 Other forms of scoliosis
0.517 0.483 0.000
M21.7 Unequal limb length (acquired)
0.516 0.484 0.000
M71.3 Other bursal cyst
0.516 0.484 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.516 0.484 0.000
M21.6 Other acquired deformities of ankle and foot
0.515 0.485 0.000
M94.2 Chondromalacia
0.515 0.485 0.000
M24.07 Loose body in joint (Ankle and foot)
0.514 0.486 0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.513 0.487 0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)
0.513 0.487 0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)
0.513 0.487 0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)
0.513 0.487 0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)
0.513 0.487 0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)
0.513 0.487 0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)
0.513 0.487 0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)
0.513 0.487 0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)
0.513 0.487 0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)
0.513 0.487 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.513 0.487 0.000
M21.0 Valgus deformity, not elsewhere classified
0.513 0.487 0.000
M84.09 Malunion of fracture (Site unspecified)
0.512 0.487 0.000
M84.08 Malunion of fracture (Other)
0.512 0.487 0.000
M84.05 Malunion of fracture (Pelvic region and thigh)
0.512 0.487 0.000
M84.00 Malunion of fracture (Multiple sites)
0.512 0.487 0.000
M24.69 Ankylosis of joint (Site unspecified)
0.511 0.488 0.000
M24.68 Ankylosis of joint (Other)
0.511 0.488 0.000
M24.66 Ankylosis of joint (Lower leg)
0.511 0.488 0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)
0.511 0.488 0.000
M24.64 Ankylosis of joint (Hand)
0.511 0.488 0.000
M24.63 Ankylosis of joint (Forearm)
0.511 0.488 0.000
M24.62 Ankylosis of joint (Upper arm)
0.511 0.488 0.000
M24.61 Ankylosis of joint (Shoulder region)
0.511 0.488 0.000
M24.60 Ankylosis of joint (Multiple sites)
0.511 0.488 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.510 0.490 0.000
M79.63 Pain in limb (Forearm)
0.510 0.490 0.000
M93 Other osteochondropathies
0.509 0.490 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.509 0.491 0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)
0.508 0.492 0.000
M65.88 Other synovitis and tenosynovitis (Other)
0.508 0.492 0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)
0.508 0.492 0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)
0.508 0.492 0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)
0.508 0.492 0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)
0.508 0.492 0.000
M13.89 Other specified arthritis (Site unspecified)
0.506 0.494 0.000
M65.39 Trigger finger-Site unspec
0.505 0.495 0.000
M65.38 Trigger finger-Other
0.505 0.495 0.000
M65.37 Trigger finger-Ankle/foot
0.505 0.495 0.000
M65.36 Trigger finger-Lower leg
0.505 0.495 0.000
M65.35 Trigger finger-Pelvic/thigh
0.505 0.495 0.000
M65.33 Trigger finger-Forearm
0.505 0.495 0.000
M65.32 Trigger finger-Upper arm
0.505 0.495 0.000
M65.31 Trigger finger-Shldr region
0.505 0.495 0.000
M65.30 Trigger finger-Mult sites
0.505 0.495 0.000
M23 Internal derangement of knee
0.504 0.496 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.504 0.496 0.000
M02.3 Reiter's disease
0.503 0.497 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.502 0.498 0.000
M76.5 Patellar tendinitis
0.502 0.498 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.501 0.499 0.000
M32.8 Other forms of systemic lupus erythematosus
0.501 0.499 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.501 0.499 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.501 0.499 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.501 0.499 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.501 0.499 0.000
M36.3 Arthropathy in other blood disorders
0.501 0.499 0.000
M36.2 Haemophilic arthropathy
0.501 0.499 0.000
M36.1 Arthropathy in neoplastic disease
0.501 0.499 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.501 0.499 0.000
M24.09 Loose body in joint (Site unspecified)
0.501 0.499 0.000
M24.08 Loose body in joint (Other)
0.501 0.499 0.000
M24.06 Loose body in joint-Lower leg
0.501 0.499 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.501 0.499 0.000
M24.04 Loose body in joint (Hand)
0.501 0.499 0.000
M24.00 Loose body in joint (Multiple sites)
0.501 0.499 0.000
M77.49 Metatarsalgia-Site unspec
0.501 0.499 0.000
M77.48 Metatarsalgia-Other
0.501 0.499 0.000
M77.46 Metatarsalgia-Lower Leg
0.501 0.499 0.000
M77.45 Metatarsalgia-Pelvic/Thigh
0.501 0.499 0.000
M77.44 Metatarsalgia-Hand
0.501 0.499 0.000
M77.43 Metatarsalgia-Forearm
0.501 0.499 0.000
M77.42 Metatarsalgia-Upper arm
0.501 0.499 0.000
M77.41 Metatarsalgia-Shldr region
0.501 0.499 0.000
M77.40 Metatarsalgia-Mult sites
0.501 0.499 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.500 0.500 0.000
M08.9 Juvenile arthritis, unspecified
0.500 0.500 0.000
M08.8 Other juvenile arthritis
0.500 0.500 0.000
M08.4 Pauciarticular juvenile arthritis
0.500 0.500 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.500 0.500 0.000
M08.2 Juvenile arthritis with systemic onset
0.500 0.500 0.000
M08.1 Juvenile ankylosing spondylitis
0.500 0.500 0.000
M08.0 Juvenile rheumatoid arthritis
0.500 0.500 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.500 0.500 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.500 0.500 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.500 0.500 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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