TreeWAS – Variant ID: rs78398654

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
M15-M19 Arthrosis	0.999	0.001
M17 Gonarthrosis [arthrosis of knee]	0.996	0.004
Chapter XX External causes of morbidity and mortality	0.994	0.006
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.993	0.007
Chapter XI Diseases of the digestive system	0.990	0.010
M20-M25 Other joint disorders	0.986	0.014
M17.9 Gonarthrosis, unspecified	0.986	0.014
K70-K77 Diseases of liver	0.985	0.015
Chapter XXI Factors influencing health status and contact with health services	0.985	0.015
M45-M49 Spondylopathies	0.981	0.019
Chapter XII Diseases of the skin and subcutaneous tissue	0.981	0.019
M25 Other joint disorders, not elsewhere classified	0.980	0.020
J40-J47 Chronic lower respiratory diseases	0.978	0.022
K76 Other diseases of liver	0.977	0.023
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.975	0.025
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.973	0.027
Z91 Personal history of risk-factors, not elsewhere classified	0.971	0.029
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.968	0.032
J30-J39 Other diseases of upper respiratory tract	0.968	0.032
Chapter VI Diseases of the nervous system	0.968	0.032
M05-M14 Inflammatory polyarthropathies	0.963	0.037
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.962	0.038
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.958	0.042
M47 Spondylosis	0.956	0.044
Chapter IX Diseases of the circulatory system	0.951	0.049
K55-K64 Other diseases of intestines	0.950	0.050
J95-J99 Other diseases of the respiratory system	0.948	0.052
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.945	0.055
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.943	0.057
M47.8 Other spondylosis	0.941	0.059
Z88.1 Personal history of allergy to other antibiotic agents	0.941	0.059
Z88.6 Personal history of allergy to analgesic agent	0.937	0.063
M47.86 Other spondylosis (Lumbar region)	0.933	0.067
K76.0 Fatty (change of) liver, not elsewhere classified	0.933	0.067
M25.7 Osteophyte	0.932	0.068
J45 Asthma	0.931	0.069
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.931	0.069
M10 Gout	0.928	0.072
I20-I25 Ischaemic heart diseases	0.927	0.073
R13 Dysphagia	0.927	0.073
Z95 Presence of cardiac and vascular implants and grafts	0.923	0.077
M25.5 Pain in joint	0.921	0.079
G90-G99 Other disorders of the nervous system	0.913	0.087
J90-J94 Other diseases of pleura	0.912	0.088
L80-L99 Other disorders of the skin and subcutaneous tissue	0.911	0.089
L00-L08 Infections of the skin and subcutaneous tissue	0.911	0.089
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.909	0.091
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.909	0.091
I25 Chronic ischaemic heart disease	0.908	0.092
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.907	0.093
J98 Other respiratory disorders	0.907	0.093
M10.9 Gout, unspecified	0.903	0.097
I95-I99 Other and unspecified disorders of the circulatory system	0.902	0.098
M65-M68 Disorders of synovium and tendon	0.902	0.098
J44 Other chronic obstructive pulmonary disease	0.900	0.100
K58 Irritable bowel syndrome	0.900	0.100
K76.9 Liver disease, unspecified	0.900	0.100
I25.8 Other forms of chronic ischaemic heart disease	0.893	0.107
Z94 Transplanted organ and tissue status	0.893	0.107
J45.9 Asthma, unspecified	0.892	0.108
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.891	0.109
M19 Other arthrosis	0.886	0.114
S20-S29 Injuries to the thorax	0.886	0.114
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.886	0.114
J38.3 Other diseases of vocal cords	0.882	0.118
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.881	0.119
K59 Other functional intestinal disorders	0.876	0.124
M25.57 Pain in joint (Ankle and foot)	0.874	0.126
Z95.0 Presence of cardiac pacemaker	0.872	0.128
M17.0 Primary gonarthrosis, bilateral	0.869	0.131
J33 Nasal polyp	0.869	0.131
R47-R49 Symptoms and signs involving speech and voice	0.866	0.134
L20-L30 Dermatitis and eczema	0.864	0.136
M80-M85 Disorders of bone density and structure	0.864	0.136
Chapter I Certain infectious and parasitic diseases	0.858	0.142
M10.99 Gout, unspecified (Site unspecified)	0.857	0.143
I95 Hypotension	0.857	0.143
R93 Abnormal findings on diagnostic imaging of other body structures	0.856	0.144
L03 Cellulitis	0.856	0.144
J38.7 Other diseases of larynx	0.855	0.145
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.854	0.146
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.850	0.150
K76.6 Portal hypertension	0.848	0.152
M25.76 Osteophyte (Lower leg)	0.847	0.153
L98.8 Other specified disorders of skin and subcutaneous tissue	0.846	0.154
Chapter VII Diseases of the eye and adnexa	0.846	0.154
G80-G83 Cerebral palsy and other paralytic syndromes	0.845	0.155
X60-X84 Intentional self-harm	0.845	0.155
I70-I79 Diseases of arteries, arterioles and capillaries	0.844	0.156
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.844	0.156
K74 Fibrosis and cirrhosis of liver	0.843	0.157
Z91.5 Personal history of self-harm	0.840	0.160
T88 Other complications of surgical and medical care, not elsewhere classified	0.839	0.161
T15-T19 Effects of foreign body entering through natural orifice	0.836	0.164
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.834	0.166
Y44 Agents primarily affecting blood constituents	0.834	0.166
R14 Flatulence and related conditions	0.834	0.166
M65 Synovitis and tenosynovitis	0.831	0.169
Y84.8 Other medical procedures	0.828	0.172
S22 Fracture of rib(s), sternum and thoracic spine	0.827	0.173
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.827	0.173
M16 Coxarthrosis [arthrosis of hip]	0.826	0.174
S70-S79 Injuries to the hip and thigh	0.823	0.177
K59.0 Constipation	0.821	0.179
J60-J70 Lung diseases due to external agents	0.819	0.181
M18 Arthrosis of first carpometacarpal joint	0.818	0.182
M17.5 Other secondary gonarthrosis	0.817	0.182
Z89 Acquired absence of limb	0.817	0.183
J47 Bronchiectasis	0.814	0.186
K58.9 Irritable bowel syndrome without diarrhoea	0.813	0.187
M22 Disorders of patella	0.813	0.187
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.813	0.187
S40-S49 Injuries to the shoulder and upper arm	0.812	0.188
I25.2 Old myocardial infarction	0.811	0.189
J90 Pleural effusion, not elsewhere classified	0.811	0.189
Z40-Z54 Persons encountering health services for specific procedures and health care	0.808	0.192
Y40 Systemic antibiotics	0.807	0.193
G70-G73 Diseases of myoneural junction and muscle	0.806	0.194
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.806	0.194
B35-B49 Mycoses	0.805	0.194
G93 Other disorders of brain	0.805	0.195
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.802	0.198
M25.55 Pain in joint (Pelvic region and thigh)	0.802	0.198
L97 Ulcer of lower limb, not elsewhere classified	0.802	0.198
L50-L54 Urticaria and erythema	0.801	0.199
L03.1 Cellulitis of other parts of limb	0.795	0.205
Z53 Persons encountering health services for specifie procedures, not carried out	0.795	0.205
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.792	0.208
K58.0 Irritable bowel syndrome with diarrhoea	0.792	0.208
X40-X49 Accidental poisoning by and exposure to noxious substances	0.792	0.208
M17.3 Other posttraumatic gonarthrosis	0.792	0.208
M25.77 Osteophyte (Ankle and foot)	0.792	0.208
M45 Ankylosing spondylitis	0.790	0.210
J98.1 Pulmonary collapse	0.790	0.210
W20-W49 Exposure to inanimate mechanical forces	0.789	0.211
J98.8 Other specified respiratory disorders	0.789	0.211
M47.80 Other spondylosis (Multiple sites in spine)	0.787	0.213
K65-K67 Diseases of peritoneum	0.787	0.213
M25.3 Other instability of joint	0.786	0.214
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.786	0.214
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.785	0.215
J44.8 Other specified chronic obstructive pulmonary disease	0.784	0.216
Z94.0 Kidney transplant status	0.783	0.217
G50-G59 Nerve, nerve root and plexus disorders	0.780	0.220
M86-M90 Other osteopathies	0.780	0.220
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.779	0.221
L84 Corns and callosities	0.777	0.223
L30 Other dermatitis	0.775	0.224
R91 Abnormal findings on diagnostic imaging of lung	0.775	0.224
I95.9 Hypotension, unspecified	0.775	0.225
Z53.0 Procedure not carried out because of contraindication	0.775	0.225
Chapter VIII Diseases of the ear and mastoid process	0.774	0.226
I22 Subsequent myocardial infarction	0.774	0.226
M10.96 Gout, unspecified (Lower leg)	0.773	0.227
K56 Paralytic ileus and intestinal obstruction without hernia	0.772	0.228
W00-W19 Falls	0.768	0.231
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.767	0.233
V80-V89 Other land transport accidents	0.767	0.233
Z95.4 Presence of other heart-valve replacement	0.766	0.234
R10 Abdominal and pelvic pain	0.766	0.234
M48 Other spondylopathies	0.765	0.235
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.764	0.235
Y51 Drugs primarily affecting the autonomic nervous system	0.764	0.236
Y84.2 Radiological procedure and radiotherapy	0.764	0.236
M25.9 Joint disorder, unspecified	0.763	0.237
T86 Failure and rejection of transplanted organs and tissues	0.761	0.239
Z94.8 Other transplanted organ and tissue status	0.761	0.239
R49 Voice disturbances	0.761	0.239
M25.6 Stiffness of joint, not elsewhere classified	0.761	0.239
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.760	0.240
G95 Other diseases of spinal cord	0.760	0.240
M60-M63 Disorders of muscles	0.757	0.243
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.756	0.244
M70-M79 Other soft tissue disorders	0.755	0.245
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.755	0.245
B37 Candidiasis	0.754	0.246
J09-J18 Influenza and pneumonia	0.754	0.246
G90 Disorders of autonomic nervous system	0.754	0.246
M84 Disorders of continuity of bone	0.753	0.247
M14 Arthropathies in other diseases classified elsewhere	0.752	0.248
J39 Other diseases of upper respiratory tract	0.751	0.249
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.750	0.250
J99 Respiratory disorders in diseases classified elsewhere	0.750	0.250
M65.9 Synovitis and tenosynovitis, unspecified	0.750	0.250
Q20-Q28 Congenital malformations of the circulatory system	0.749	0.251
M91-M94 Chondropathies	0.749	0.251
M35 Other systemic involvement of connective tissue	0.748	0.252
M19.9 Arthrosis, unspecified	0.748	0.252
M25.75 Osteophyte (Pelvic region and thigh)	0.747	0.253
M40-M43 Deforming dorsopathies	0.746	0.253
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.746	0.254
Y44.2 Anticoagulants	0.746	0.254
Z34 Supervision of normal pregnancy	0.746	0.254
H53-H54 Visual disturbances and blindness	0.743	0.257
S22.4 Multiple fractures of ribs	0.743	0.257
K72 Hepatic failure, not elsewhere classified	0.742	0.258
K74.6 Other and unspecified cirrhosis of liver	0.741	0.259
H10-H13 Disorders of conjunctiva	0.740	0.260
Y84.0 Cardiac catheterisation	0.740	0.260
M19.0 Primary arthrosis of other joints	0.740	0.260
L98.0 Pyogenic granuloma	0.740	0.260
M00-M03 Infectious arthropathies	0.739	0.260
R12 Heartburn	0.739	0.261
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.739	0.261
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.738	0.262
Y43 Primarily systemic agents	0.737	0.263
M25.8 Other specified joint disorders	0.734	0.266
J38.0 Paralysis of vocal cords and larynx	0.733	0.267
L02 Cutaneous abscess, furuncle and carbuncle	0.733	0.267
M25.53 Pain in joint (Forearm)	0.732	0.268
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.732	0.268
J33.0 Polyp of nasal cavity	0.731	0.269
J98.4 Other disorders of lung	0.731	0.269
J91 Pleural effusion in conditions classified elsewhere	0.730	0.270
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.730	0.270
G00-G09 Inflammatory diseases of the central nervous system	0.730	0.270
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.730	0.270
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.730	0.270
M06 Other rheumatoid arthritis	0.729	0.271
R22.2 Localised swelling, mass and lump, trunk	0.729	0.271
Y52 Agents primarily affecting the cardiovascular system	0.727	0.273
Z88.3 Personal history of allergy to other anti-infective agents	0.726	0.273
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.726	0.274
J46 Status asthmaticus	0.725	0.275
M21 Other acquired deformities of limbs	0.724	0.276
K75 Other inflammatory liver diseases	0.724	0.276
Y57 Other and unspecified drugs and medicaments	0.724	0.276
J33.9 Nasal polyp, unspecified	0.722	0.278
R23 Other skin changes	0.722	0.278
Q38-Q45 Other congenital malformations of the digestive system	0.722	0.278
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.721	0.279
Chapter XXII Codes for special purposes	0.719	0.281
J36 Peritonsillar abscess	0.718	0.282
M07 Psoriatic and enteropathic arthropathies	0.718	0.282
J38.2 Nodules of vocal cords	0.717	0.282
M24 Other specific joint derangements	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M15 Polyarthrosis	0.716	0.284
T80 Complications following infusion, transfusion and therapeutic injection	0.716	0.284
T66-T78 Other and unspecified effects of external causes	0.716	0.284
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.715	0.285
S72 Fracture of femur	0.714	0.286
M17.4 Other secondary gonarthrosis, bilateral	0.714	0.286
M17.2 Posttraumatic gonarthrosis, bilateral	0.714	0.286
S42 Fracture of shoulder and upper arm	0.713	0.287
K35-K38 Diseases of appendix	0.713	0.287
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.712	0.288
Y35-Y36 Legal intervention and operations of war	0.712	0.288
Y10-Y34 Event of undetermined intent	0.712	0.288
Y00-Y09 Assault	0.712	0.288
X85-X99 Assault	0.712	0.288
X58-X59 Accidental exposure to other and unspecified factors	0.712	0.288
X50-X57 Overexertion, travel and privation	0.712	0.288
X30-X39 Exposure to forces of nature	0.712	0.288
X20-X29 Contact with venomous animals and plants	0.712	0.288
X10-X19 Contact with heat and hot substances	0.712	0.288
X00-X09 Exposure to smoke, fire and flames	0.712	0.288
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.712	0.288
W75-W84 Other accidental threats to breathing	0.712	0.288
W65-W74 Accidental drowning and submersion	0.712	0.288
W50-W64 Exposure to animate mechanical forces	0.712	0.288
V98-V99 Other and unspecified transport accidents	0.712	0.288
V95-V97 Air and space transport accidents	0.712	0.288
V90-V94 Water transport accidents	0.712	0.288
V70-V79 Bus occupant injured in transport accident	0.712	0.288
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.712	0.288
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.712	0.288
V40-V49 Car occupant injured in transport accident	0.712	0.288
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.712	0.288
V01-V09 Pedestrian injured in transport accident	0.712	0.288
R95-R99 Ill-defined and unknown causes of mortality	0.712	0.288
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.712	0.288
L30.9 Dermatitis, unspecified	0.712	0.288
T82.1 Mechanical complication of cardiac electronic device	0.712	0.288
I95.1 Orthostatic hypotension	0.710	0.290
Z95.1 Presence of aortocoronary bypass graft	0.710	0.290
K70 Alcoholic liver disease	0.709	0.291
M65.4 Radial styloid tenosynovitis [de Quervain]	0.709	0.291
I71 Aortic aneurysm and dissection	0.707	0.293
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.707	0.293
M34 Systemic sclerosis	0.707	0.293
M33 Dermatopolymyositis	0.707	0.293
M32 Systemic lupus erythematosus	0.707	0.293
M30 Polyarteritis nodosa and related conditions	0.707	0.293
K77 Liver disorders in diseases classified elsewhere	0.706	0.294
K73 Chronic hepatitis, not elsewhere classified	0.706	0.294
K71 Toxic liver disease	0.706	0.294
K76.8 Other specified diseases of liver	0.706	0.294
M10.97 Gout, unspecified (Ankle and foot)	0.705	0.295
M85 Other disorders of bone density and structure	0.705	0.295
J45.0 Predominantly allergic asthma	0.704	0.296
M19.94 Arthrosis, unspecified (Hand)	0.704	0.296
K59.8 Other specified functional intestinal disorders	0.703	0.296
M49 Spondylopathies in diseases classified elsewhere	0.703	0.297
L10-L14 Bullous disorders	0.703	0.297
H52 Disorders of refraction and accommodation	0.703	0.297
D68 Other coagulation defects	0.703	0.297
G99 Other disorders of nervous system in diseases classified elsewhere	0.703	0.297
M25.2 Flail joint	0.702	0.298
M25.1 Fistula of joint	0.702	0.298
M25.0 Haemarthrosis	0.702	0.298
K61 Abscess of anal and rectal regions	0.702	0.298
M47.9 Spondylosis, unspecified	0.702	0.298
J98.0 Diseases of bronchus, not elsewhere classified	0.702	0.298
R20 Disturbances of skin sensation	0.702	0.298
L03.0 Cellulitis of finger and toe	0.701	0.299
J41 Simple and mucopurulent chronic bronchitis	0.701	0.299
K76.7 Hepatorenal syndrome	0.701	0.299
K76.5 Hepatic veno-occlusive disease	0.701	0.299
K76.4 Peliosis hepatis	0.701	0.299
K76.3 Infarction of liver	0.701	0.299
K76.2 Central haemorrhagic necrosis of liver	0.701	0.299
K76.1 Chronic passive congestion of liver	0.701	0.299
Z29 Need for other prophylactic measures	0.701	0.299
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.700	0.299
T79-T79 Certain early complications of trauma	0.700	0.300
Z30 Contraceptive management	0.700	0.300
K86 Other diseases of pancreas	0.700	0.300
Z97 Presence of other devices	0.699	0.300
T33-T35 Frostbite	0.699	0.301
T26-T28 Burns and corrosions confined to eye and internal organs	0.699	0.301
T20-T25 Burns and corrosions of external body surface, specified by site	0.699	0.301
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.699	0.301
T00-T07 Injuries involving multiple body regions	0.699	0.301
S10-S19 Injuries to the neck	0.699	0.301
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.698	0.302
Z84 Family history of other conditions	0.698	0.302
Z81 Family history of mental and behavioural disorders	0.698	0.302
I95.2 Hypotension due to drugs	0.698	0.302
L03.8 Cellulitis of other sites	0.697	0.302
T88.4 Failed or difficult intubation	0.697	0.303
I21 Acute myocardial infarction	0.697	0.303
Z95.5 Presence of coronary angioplasty implant and graft	0.697	0.303
R22.0 Localised swelling, mass and lump, head	0.696	0.304
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.696	0.304
Z91.7 Personal history of female genital mutilation	0.696	0.304
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.696	0.304
Z91.3 Personal history of unhealthy sleep-wake schedule	0.696	0.304
Z91.2 Personal history of poor personal hygiene	0.696	0.304
Z88.5 Personal history of allergy to narcotic agent	0.696	0.304
I72 Other aneurysm	0.696	0.304
T18 Foreign body in alimentary tract	0.695	0.305
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.695	0.305
J80-J84 Other respiratory diseases principally affecting the interstitium	0.695	0.305
G82 Paraplegia and tetraplegia	0.694	0.306
J37 Chronic laryngitis and laryngotracheitis	0.694	0.306
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.694	0.306
V10-V19 Pedal cyclist injured in transport accident	0.693	0.307
R79 Other abnormal findings of blood chemistry	0.692	0.308
Z92 Personal history of medical treatment	0.692	0.308
R02 Gangrene, not elsewhere classified	0.692	0.308
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.692	0.308
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.691	0.309
K83 Other diseases of biliary tract	0.691	0.309
Z89.6 Acquired absence of leg above knee	0.691	0.309
M12 Other specific arthropathies	0.690	0.310
M09 Juvenile arthritis in diseases classified elsewhere	0.690	0.310
M08 Juvenile arthritis	0.690	0.310
M25.78 Osteophyte (Other)	0.690	0.310
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.690	0.310
J69 Pneumonitis due to solids and liquids	0.689	0.311
B37.0 Candidal stomatitis	0.688	0.312
M79 Other soft tissue disorders, not elsewhere classified	0.688	0.312
Y59 Other and unspecified vaccines and biological substances	0.687	0.313
Y58 Bacterial vaccines	0.687	0.313
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.687	0.313
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.687	0.313
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.687	0.313
Y53 Agents primarily affecting the gastro-intestinal system	0.687	0.313
Y50 Central nervous system stimulants, not elsewhere classified	0.687	0.313
Y49 Psychotropic drugs, not elsewhere classified	0.687	0.313
Y48 Anaesthetics and therapeutic gases	0.687	0.313
Y47 Sedatives, hypnotics and antianxiety drugs	0.687	0.313
Y46 Antiepileptics and anti-Parkinsonism drugs	0.687	0.313
Y41 Other systemic anti-infectives and antiparasitics	0.687	0.313
R10.3 Pain localised to other parts of lower abdomen	0.687	0.313
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.687	0.313
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.686	0.314
M46 Other inflammatory spondylopathies	0.686	0.314
M47.1 Other spondylosis with myelopathy	0.685	0.314
M47.0 Anterior spinal and vertebral artery compression syndromes	0.685	0.314
R49.0 Dysphonia	0.686	0.314
S22.40 Multiple fractures of ribs (closed)	0.684	0.316
M11 Other crystal arthropathies	0.683	0.317
I21.0 Acute transmural myocardial infarction of anterior wall	0.683	0.317
T88.7 Unspecified adverse effect of drug or medicament	0.682	0.318
I00-I02 Acute rheumatic fever	0.682	0.318
K64 Haemorrhoids and perianal venous thrombosis	0.681	0.318
V20-V29 Motorcycle rider injured in transport accident	0.681	0.319
K56.6 Other and unspecified intestinal obstruction	0.680	0.320
J96 Respiratory failure, not elsewhere classified	0.680	0.320
M19.99 Arthrosis, unspecified (Site unspecified)	0.679	0.321
G83 Other paralytic syndromes	0.679	0.321
I73 Other peripheral vascular diseases	0.679	0.321
K60 Fissure and fistula of anal and rectal regions	0.678	0.322
M25.54 Pain in joint (Hand)	0.678	0.322
R07 Pain in throat and chest	0.678	0.322
M13 Other arthritis	0.677	0.323
M16.1 Other primary coxarthrosis	0.676	0.324
K63 Other diseases of intestine	0.676	0.324
J38.6 Stenosis of larynx	0.676	0.324
J38.5 Laryngeal spasm	0.676	0.324
J38.4 Oedema of larynx	0.676	0.324
S90-S99 Injuries to the ankle and foot	0.676	0.324
M25.51 Pain in joint (Shoulder region)	0.675	0.324
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.675	0.325
A00-A09 Intestinal infectious diseases	0.675	0.325
M47.89 Other spondylosis (Site unspecified)	0.675	0.325
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.675	0.325
M47.85 Other spondylosis (Thoracolumbar region)	0.675	0.325
M47.84 Other spondylosis (Thoracic region)	0.675	0.325
M47.83 Other spondylosis (Cervicothoracic region)	0.675	0.325
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.675	0.325
G30-G32 Other degenerative diseases of the nervous system	0.675	0.325
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.674	0.326
I10-I15 Hypertensive diseases	0.673	0.327
K85 Acute pancreatitis	0.673	0.327
Z83 Family history of other specific disorders	0.672	0.327
J93 Pneumothorax	0.672	0.328
G35-G37 Demyelinating diseases of the central nervous system	0.672	0.328
G93.4 Encephalopathy, unspecified	0.671	0.329
B37.9 Candidiasis, unspecified	0.671	0.329
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.671	0.329
Y60-Y69 Misadventures to patients during surgical and medical care	0.670	0.330
Q80-Q89 Other congenital malformations	0.670	0.330
K81 Cholecystitis	0.669	0.331
J92 Pleural plaque	0.668	0.332
M31 Other necrotising vasculopathies	0.668	0.332
M84.1 Nonunion of fracture [pseudarthrosis]	0.668	0.332
M25.79 Osteophyte (Site unspecified)	0.668	0.332
M25.73 Osteophyte (Forearm)	0.668	0.332
M25.72 Osteophyte (Upper arm)	0.668	0.332
M25.71 Osteophyte (Shoulder region)	0.668	0.332
M25.70 Osteophyte (Multiple sites)	0.668	0.332
L91 Hypertrophic disorders of skin	0.668	0.332
T17 Foreign body in respiratory tract	0.668	0.332
J45.8 Mixed asthma	0.667	0.332
J45.1 Nonallergic asthma	0.667	0.332
T87 Complications peculiar to reattachment and amputation	0.667	0.333
W44 Foreign body entering into or through eye or natural orifice	0.667	0.333
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.666	0.334
Q60-Q64 Congenital malformations of the urinary system	0.666	0.334
M10.4 Other secondary gout	0.665	0.335
M10.3 Gout due to impairment of renal function	0.665	0.335
M10.2 Drug-induced gout	0.665	0.335
M10.1 Lead-induced gout	0.665	0.335
M10.0 Idiopathic gout	0.665	0.335
I23 Certain current complications following acute myocardial infarction	0.665	0.335
S22.0 Fracture of thoracic vertebra	0.664	0.336
Chapter XV Pregnancy, childbirth and the puerperium	0.664	0.336
R07.4 Chest pain, unspecified	0.663	0.337
J35 Chronic diseases of tonsils and adenoids	0.662	0.338
G93.2 Benign intracranial hypertension	0.662	0.338
I99 Other and unspecified disorders of circulatory system	0.661	0.338
R10.1 Pain localised to upper abdomen	0.662	0.338
X62.9 Unspecified place	0.661	0.339
M22.8 Other disorders of patella	0.661	0.339
M25.59 Pain in joint (Site unspecified)	0.660	0.340
M25.58 Pain in joint (Other)	0.660	0.340
M25.52 Pain in joint (Upper arm)	0.660	0.340
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.660	0.340
K82 Other diseases of gallbladder	0.659	0.341
J00-J06 Acute upper respiratory infections	0.658	0.342
J40 Bronchitis, not specified as acute or chronic	0.656	0.344
J33.8 Other polyp of sinus	0.656	0.344
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.656	0.344
Z95.2 Presence of prosthetic heart valve	0.655	0.345
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.654	0.346
G94 Other disorders of brain in diseases classified elsewhere	0.654	0.346
G98 Other disorders of nervous system, not elsewhere classified	0.654	0.346
G92 Toxic encephalopathy	0.654	0.346
J94 Other pleural conditions	0.654	0.346
M45.X9 Ankylosing spondylitis (Site unspecified)	0.654	0.346
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.654	0.346
L28 Lichen simplex chronicus and prurigo	0.654	0.346
L03.2 Cellulitis of face	0.654	0.346
Z95.3 Presence of xenogenic heart valve	0.653	0.346
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.653	0.347
L95 Vasculitis limited to skin, not elsewhere classified	0.653	0.347
L94 Other localised connective tissue disorders	0.653	0.347
L93 Lupus erythematosus	0.653	0.347
L92 Granulomatous disorders of skin and subcutaneous tissue	0.653	0.347
L87 Transepidermal elimination disorders	0.653	0.347
L88 Pyoderma gangrenosum	0.653	0.347
L86 Keratoderma in diseases classified elsewhere	0.653	0.347
L83 Acanthosis nigricans	0.653	0.347
L80 Vitiligo	0.653	0.347
L04 Acute lymphadenitis	0.653	0.347
L01 Impetigo	0.653	0.347
L00 Staphylococcal scalded skin syndrome	0.653	0.347
R47 Speech disturbances, not elsewhere classified	0.653	0.347
R92 Abnormal findings on diagnostic imaging of breast	0.652	0.348
R04 Haemorrhage from respiratory passages	0.651	0.349
I25.6 Silent myocardial ischaemia	0.651	0.349
I25.4 Coronary artery aneurysm	0.651	0.349
I25.3 Aneurysm of heart	0.651	0.349
I25.0 Atherosclerotic cardiovascular disease, so described	0.651	0.349

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations