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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78414518
log Bayes Factor = 7.79778
Chromosome 17   position 7,478,402  (GRCh37) Explore rs78414518 on Ensembl!
Variant rs78414518 is part of Cluster X0113

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D25 Leiomyoma of uterus
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
D25.9 Leiomyoma of uterus, unspecified
1.000 0.000 0.000
G90-G99 Other disorders of the nervous system
0.999 0.001 0.000
D25.0 Submucous leiomyoma of uterus
0.998 0.002 0.000
Chapter II Neoplasms
0.998 0.002 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.995 0.005 0.000
C44 Other malignant neoplasms of skin
0.993 0.007 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.993 0.007 0.000
C44.3 Skin of other and unspecified parts of face
0.991 0.009 0.000
D25.1 Intramural leiomyoma of uterus
0.991 0.009 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.977 0.023 0.000
M20-M25 Other joint disorders
0.970 0.030 0.000
G93 Other disorders of brain
0.969 0.031 0.000
D10-D36 Benign neoplasms
0.961 0.039 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.959 0.041 0.000
G40-G47 Episodic and paroxysmal disorders
0.957 0.043 0.000
G56.0 Carpal tunnel syndrome
0.951 0.049 0.000
M25 Other joint disorders, not elsewhere classified
0.950 0.050 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.949 0.051 0.000
G56 Mononeuropathies of upper limb
0.948 0.052 0.000
G91 Hydrocephalus
0.943 0.057 0.000
D45 Polycythaemia vera
0.943 0.057 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.942 0.058 0.000
M65-M68 Disorders of synovium and tendon
0.941 0.059 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.931 0.069 0.000
M25.4 Effusion of joint
0.931 0.069 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.931 0.069 0.000
L20-L30 Dermatitis and eczema
0.929 0.071 0.000
G40 Epilepsy
0.928 0.072 0.000
C44.1 Skin of eyelid, including canthus
0.922 0.078 0.000
D25.2 Subserosal leiomyoma of uterus
0.922 0.078 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.915 0.085 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.914 0.086 0.000
E50-E64 Other nutritional deficiencies
0.910 0.090 0.000
E70-E90 Metabolic disorders
0.910 0.090 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.907 0.093 0.000
G91.9 Hydrocephalus, unspecified
0.900 0.100 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.899 0.101 0.000
G95 Other diseases of spinal cord
0.899 0.101 0.000
E53 Deficiency of other B group vitamins
0.897 0.103 0.000
L27 Dermatitis due to substances taken internally
0.893 0.107 0.000
E86 Volume depletion
0.893 0.107 0.000
G93.9 Disorder of brain, unspecified
0.888 0.112 0.000
E53.8 Deficiency of other specified B group vitamins
0.888 0.112 0.000
S90-S99 Injuries to the ankle and foot
0.886 0.114 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.879 0.121 0.000
M25.46 Effusion of joint (Lower leg)
0.875 0.125 0.000
G30-G32 Other degenerative diseases of the nervous system
0.869 0.131 0.000
C44.5 Skin of trunk
0.867 0.133 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.867 0.133 0.000
G93.2 Benign intracranial hypertension
0.866 0.134 0.000
M86-M90 Other osteopathies
0.864 0.136 0.000
S50-S59 Injuries to the elbow and forearm
0.859 0.141 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.858 0.142 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.855 0.145 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.854 0.146 0.000
D32 Benign neoplasm of meninges
0.853 0.147 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.853 0.147 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.851 0.149 0.000
D41.0 Kidney
0.845 0.155 0.000
Y52 Agents primarily affecting the cardiovascular system
0.844 0.156 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.843 0.157 0.000
W50-W64 Exposure to animate mechanical forces
0.841 0.158 0.000
M65 Synovitis and tenosynovitis
0.841 0.159 0.000
G93.8 Other specified disorders of brain
0.841 0.159 0.000
D37.4 Colon
0.838 0.162 0.000
Chapter I Certain infectious and parasitic diseases
0.837 0.163 0.000
D10 Benign neoplasm of mouth and pharynx
0.836 0.164 0.000
Y45.1 Salicylates
0.834 0.165 0.000
C71 Malignant neoplasm of brain
0.833 0.167 0.000
Y84.6 Urinary catheterisation
0.829 0.171 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.828 0.172 0.000
Chapter X Diseases of the respiratory system
0.825 0.175 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.824 0.176 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.820 0.180 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.820 0.180 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.819 0.181 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.814 0.186 0.000
D37.7 Other digestive organs
0.809 0.191 0.000
M22 Disorders of patella
0.808 0.192 0.000
M67 Other disorders of synovium and tendon
0.808 0.192 0.000
J00-J06 Acute upper respiratory infections
0.806 0.194 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.805 0.195 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.805 0.195 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.804 0.196 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.804 0.196 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.803 0.197 0.000
V80-V89 Other land transport accidents
0.801 0.199 0.000
G93.6 Cerebral oedema
0.800 0.200 0.000
M25.47 Effusion of joint (Ankle and foot)
0.799 0.201 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.799 0.201 0.000
M25.3 Other instability of joint
0.798 0.202 0.000
C43 Malignant melanoma of skin
0.797 0.203 0.000
G90 Disorders of autonomic nervous system
0.796 0.204 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.796 0.204 0.000
D41.4 Bladder
0.794 0.206 0.000
M25.8 Other specified joint disorders
0.793 0.207 0.000
M80-M85 Disorders of bone density and structure
0.792 0.208 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.791 0.209 0.000
S92 Fracture of foot, except ankle
0.784 0.216 0.000
G40.9 Epilepsy, unspecified
0.783 0.217 0.000
L21 Seborrhoeic dermatitis
0.783 0.217 0.000
B35-B49 Mycoses
0.783 0.217 0.000
S91 Open wound of ankle and foot
0.783 0.217 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.782 0.217 0.000
L28 Lichen simplex chronicus and prurigo
0.781 0.219 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.781 0.219 0.000
J40-J47 Chronic lower respiratory diseases
0.779 0.221 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.775 0.225 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.774 0.226 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.773 0.227 0.000
Y58 Bacterial vaccines
0.773 0.227 0.000
J03 Acute tonsillitis
0.772 0.228 0.000
T00-T07 Injuries involving multiple body regions
0.771 0.229 0.000
M25.44 Effusion of joint (Hand)
0.770 0.230 0.000
C64-C68 Malignant neoplasms of urinary tract
0.769 0.231 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.769 0.231 0.000
W00-W19 Falls
0.768 0.232 0.000
T79-T79 Certain early complications of trauma
0.765 0.235 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.763 0.237 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.763 0.237 0.000
L10-L14 Bullous disorders
0.762 0.238 0.000
M60-M63 Disorders of muscles
0.761 0.239 0.000
G95.2 Cord compression, unspecified
0.760 0.240 0.000
D33.3 Cranial nerves
0.760 0.240 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.760 0.240 0.000
G93.0 Cerebral cysts
0.759 0.241 0.000
M21 Other acquired deformities of limbs
0.759 0.241 0.000
T21 Burn and corrosion of trunk
0.759 0.241 0.000
Y48 Anaesthetics and therapeutic gases
0.759 0.241 0.000
M66 Spontaneous rupture of synovium and tendon
0.757 0.243 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.757 0.243 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.756 0.243 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.756 0.244 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.756 0.244 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.754 0.246 0.000
M30 Polyarteritis nodosa and related conditions
0.754 0.246 0.000
X20-X29 Contact with venomous animals and plants
0.753 0.247 0.000
J03.9 Acute tonsillitis, unspecified
0.748 0.252 0.000
D10.3 Other and unspecified parts of mouth
0.748 0.252 0.000
G81 Hemiplegia
0.746 0.253 0.000
S50 Superficial injury of forearm
0.746 0.254 0.000
V01-V09 Pedestrian injured in transport accident
0.746 0.254 0.000
E80.4 Gilbert's syndrome
0.745 0.255 0.000
C71.1 Frontal lobe
0.743 0.257 0.000
M24 Other specific joint derangements
0.743 0.257 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.740 0.260 0.000
X60-X84 Intentional self-harm
0.740 0.260 0.000
G41 Status epilepticus
0.740 0.260 0.000
G56.3 Lesion of radial nerve
0.739 0.261 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.738 0.262 0.000
E84 Cystic fibrosis
0.738 0.262 0.000
S32 Fracture of lumbar spine and pelvis
0.737 0.263 0.000
Y54.8 Agents affecting uric acid metabolism
0.737 0.263 0.000
M23 Internal derangement of knee
0.735 0.265 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.735 0.265 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.735 0.265 0.000
S52 Fracture of forearm
0.735 0.265 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.735 0.265 0.000
M33 Dermatopolymyositis
0.734 0.266 0.000
D46 Myelodysplastic syndromes
0.734 0.266 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.733 0.267 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.732 0.268 0.000
G95.9 Disease of spinal cord, unspecified
0.732 0.268 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.732 0.268 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.730 0.270 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.730 0.270 0.000
C69 Malignant neoplasm of eye and adnexa
0.729 0.271 0.000
D32.0 Cerebral meninges
0.728 0.272 0.000
J00 Acute nasopharyngitis [common cold]
0.728 0.272 0.000
Y00-Y09 Assault
0.728 0.272 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.727 0.273 0.000
M25.5 Pain in joint
0.726 0.274 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.724 0.276 0.000
M67.8 Other specified disorders of synovium and tendon
0.723 0.277 0.000
C44.2 Skin of ear and external auricular canal
0.722 0.278 0.000
S91.3 Open wound of other parts of foot
0.722 0.278 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.722 0.278 0.000
M25.9 Joint disorder, unspecified
0.722 0.278 0.000
B37 Candidiasis
0.721 0.279 0.000
W07 Fall involving chair
0.718 0.282 0.000
G95.8 Other specified diseases of spinal cord
0.717 0.283 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.716 0.284 0.000
G92 Toxic encephalopathy
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.715 0.285 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.715 0.285 0.000
Y40 Systemic antibiotics
0.713 0.287 0.000
C44.8 Overlapping lesion of skin
0.712 0.288 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.712 0.288 0.000
M34 Systemic sclerosis
0.711 0.288 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.711 0.289 0.000
Y54.3 Benzothiadiazine derivatives
0.710 0.290 0.000
E61 Deficiency of other nutrient elements
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.708 0.292 0.000
M88 Paget's disease of bone [osteitis deformans]
0.706 0.294 0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.706 0.294 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.705 0.295 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.704 0.295 0.000
S80-S89 Injuries to the knee and lower leg
0.704 0.296 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.704 0.296 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.704 0.296 0.000
Chapter XXII Codes for special purposes
0.704 0.296 0.000
X10-X19 Contact with heat and hot substances
0.702 0.298 0.000
Y59 Other and unspecified vaccines and biological substances
0.701 0.299 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.701 0.299 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.701 0.299 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.701 0.299 0.000
C45 Mesothelioma
0.699 0.301 0.000
G40.5 Special epileptic syndromes
0.698 0.302 0.000
G31.2 Degeneration of nervous system due to alcohol
0.698 0.302 0.000
Y57 Other and unspecified drugs and medicaments
0.696 0.304 0.000
J46 Status asthmaticus
0.696 0.304 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.696 0.304 0.000
M32 Systemic lupus erythematosus
0.696 0.304 0.000
G93.7 Reye's syndrome
0.695 0.305 0.000
G93.5 Compression of brain
0.695 0.305 0.000
G44 Other headache syndromes
0.695 0.305 0.000
G58 Other mononeuropathies
0.693 0.307 0.000
Y54.5 Other diuretics
0.691 0.309 0.000
X50-X57 Overexertion, travel and privation
0.691 0.309 0.000
M89 Other disorders of bone
0.691 0.309 0.000
E73 Lactose intolerance
0.691 0.309 0.000
G91.1 Obstructive hydrocephalus
0.691 0.309 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.690 0.310 0.000
G93.4 Encephalopathy, unspecified
0.689 0.311 0.000
D31 Benign neoplasm of eye and adnexa
0.689 0.311 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.689 0.311 0.000
D19 Benign neoplasm of mesothelial tissue
0.689 0.311 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.689 0.311 0.000
D44.6 Carotid body
0.688 0.312 0.000
M31 Other necrotising vasculopathies
0.688 0.312 0.000
G91.2 Normal-pressure hydrocephalus
0.687 0.313 0.000
J40 Bronchitis, not specified as acute or chronic
0.687 0.313 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.686 0.314 0.000
M22.8 Other disorders of patella
0.686 0.314 0.000
Y45.2 Propionic acid derivatives
0.686 0.314 0.000
M65.3 Trigger finger
0.686 0.314 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.685 0.315 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.685 0.315 0.000
W55 Bitten or struck by other mammals
0.684 0.316 0.000
M00-M03 Infectious arthropathies
0.683 0.317 0.000
M25.2 Flail joint
0.681 0.319 0.000
M25.1 Fistula of joint
0.681 0.319 0.000
M80 Osteoporosis with pathological fracture
0.681 0.319 0.000
G52 Disorders of other cranial nerves
0.681 0.319 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.680 0.320 0.000
G56.4 Causalgia
0.680 0.320 0.000
G56.1 Other lesions of median nerve
0.680 0.320 0.000
L21.9 Seborrhoeic dermatitis, unspecified
0.679 0.321 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.679 0.321 0.000
L91 Hypertrophic disorders of skin
0.678 0.322 0.000
D23 Other benign neoplasms of skin
0.678 0.322 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.678 0.322 0.000
J42 Unspecified chronic bronchitis
0.677 0.323 0.000
L23 Allergic contact dermatitis
0.677 0.323 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.677 0.323 0.000
G31.8 Other specified degenerative diseases of nervous system
0.677 0.323 0.000
G91.8 Other hydrocephalus
0.676 0.324 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.676 0.324 0.000
G91.0 Communicating hydrocephalus
0.676 0.324 0.000
Y84.4 Aspiration of fluid
0.676 0.324 0.000
B50-B64 Protozoal diseases
0.676 0.324 0.000
T33-T35 Frostbite
0.675 0.325 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.675 0.325 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.675 0.325 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.675 0.325 0.000
Y44 Agents primarily affecting blood constituents
0.675 0.325 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.674 0.325 0.000
Y84.0 Cardiac catheterisation
0.673 0.327 0.000
S90 Superficial injury of ankle and foot
0.673 0.327 0.000
D29 Benign neoplasm of male genital organs
0.673 0.327 0.000
D30 Benign neoplasm of urinary organs
0.672 0.327 0.000
L94 Other localised connective tissue disorders
0.671 0.329 0.000
M25.37 Other instability of joint (Ankle and foot)
0.671 0.329 0.000
G81.9 Hemiplegia, unspecified
0.671 0.329 0.000
J95-J99 Other diseases of the respiratory system
0.669 0.331 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.668 0.332 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.668 0.332 0.000
M25.49 Effusion of joint (Site unspecified)
0.667 0.332 0.000
M25.48 Effusion of joint (Other)
0.667 0.332 0.000
M25.43 Effusion of joint (Forearm)
0.667 0.332 0.000
M25.42 Effusion of joint (Upper arm)
0.667 0.332 0.000
M25.41 Effusion of joint (Shoulder region)
0.667 0.332 0.000
M25.40 Effusion of joint (Multiple sites)
0.667 0.332 0.000
D32.9 Meninges, unspecified
0.667 0.333 0.000
D41.9 Urinary organ, unspecified
0.667 0.333 0.000
D41.7 Other urinary organs
0.667 0.333 0.000
D41.3 Urethra
0.667 0.333 0.000
D41.2 Ureter
0.667 0.333 0.000
D41.1 Renal pelvis
0.667 0.333 0.000
V20-V29 Motorcycle rider injured in transport accident
0.667 0.333 0.000
L28.0 Lichen simplex chronicus
0.667 0.333 0.000
L25 Unspecified contact dermatitis
0.666 0.334 0.000
L24 Irritant contact dermatitis
0.666 0.334 0.000
L26 Exfoliative dermatitis
0.666 0.334 0.000
L22 Diaper [napkin] dermatitis
0.666 0.334 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.666 0.334 0.000
S52.1 Fracture of upper end of radius
0.666 0.334 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.666 0.334 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.666 0.334 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.666 0.334 0.000
M87 Osteonecrosis
0.665 0.335 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.665 0.335 0.000
B37.3 Candidiasis of vulva and vagina
0.664 0.336 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.664 0.336 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.663 0.337 0.000
G96 Other disorders of central nervous system
0.662 0.338 0.000
G45.3 Amaurosis fugax
0.662 0.338 0.000
T23 Burn and corrosion of wrist and hand
0.662 0.338 0.000
D37.6 Liver, gallbladder and bile ducts
0.660 0.340 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.660 0.340 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.658 0.342 0.000
G50 Disorders of trigeminal nerve
0.657 0.343 0.000
M25.86 Other specified joint disorders (Lower leg)
0.657 0.343 0.000
G56.8 Other mononeuropathies of upper limb
0.656 0.343 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.656 0.344 0.000
D32.1 Spinal meninges
0.656 0.344 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.656 0.344 0.000
C70 Malignant neoplasm of meninges
0.656 0.344 0.000
Y45.8 Other analgesics and antipyretics
0.656 0.344 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.656 0.344 0.000
Y45.5 4-Aminophenol derivatives
0.656 0.344 0.000
Y45.4 Antirheumatics
0.656 0.344 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.656 0.344 0.000
W07.0 Home
0.655 0.345 0.000
G54 Nerve root and plexus disorders
0.654 0.345 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.654 0.346 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.654 0.346 0.000
D37.9 Digestive organ, unspecified
0.654 0.346 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.653 0.347 0.000
L30 Other dermatitis
0.653 0.347 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.653 0.347 0.000
E63 Other nutritional deficiencies
0.653 0.347 0.000
E56 Other vitamin deficiencies
0.653 0.347 0.000
E51 Thiamine deficiency
0.653 0.347 0.000
E50 Vitamin A deficiency
0.653 0.347 0.000
E60 Dietary zinc deficiency
0.653 0.347 0.000
E59 Dietary selenium deficiency
0.653 0.347 0.000
E58 Dietary calcium deficiency
0.653 0.347 0.000
E54 Ascorbic acid deficiency
0.653 0.347 0.000
E52 Niacin deficiency [pellagra]
0.653 0.347 0.000
M23.0 Cystic meniscus
0.653 0.347 0.000
E79 Disorders of purine and pyrimidine metabolism
0.652 0.348 0.000
E77 Disorders of glycoprotein metabolism
0.652 0.348 0.000
E76 Disorders of glycosaminoglycan metabolism
0.652 0.348 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.652 0.348 0.000
E74 Other disorders of carbohydrate metabolism
0.652 0.348 0.000
E72 Other disorders of amino-acid metabolism
0.652 0.348 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.652 0.348 0.000
E70 Disorders of aromatic amino-acid metabolism
0.652 0.348 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.652 0.348 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.652 0.348 0.000
T01 Open wounds involving multiple body regions
0.652 0.348 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.650 0.350 0.000
D37.3 Appendix
0.650 0.350 0.000
D37.2 Small intestine
0.650 0.350 0.000
D37.0 Lip, oral cavity and pharynx
0.650 0.350 0.000
S50.8 Other superficial injuries of forearm
0.649 0.351 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.649 0.351 0.000
G46.4 Cerebellar stroke syndrome
0.647 0.353 0.000
M84 Disorders of continuity of bone
0.647 0.353 0.000
T21.0 Burn of unspecified degree of trunk
0.647 0.353 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.646 0.354 0.000
J44 Other chronic obstructive pulmonary disease
0.646 0.354 0.000
G43 Migraine
0.646 0.354 0.000
S37 Injury of urinary and pelvic organs
0.645 0.355 0.000
Y54.9 Mineral salts, not elsewhere classified
0.645 0.355 0.000
Y54.7 Agents affecting calcification
0.645 0.355 0.000
Y54.6 Electrolytic, caloric and water-balance agents
0.645 0.355 0.000
Y54.4 Loop [high-ceiling] diuretics
0.645 0.355 0.000
Y54.2 Carbonic-anhydrase inhibitors
0.645 0.355 0.000
Y54.0 Mineralocorticoids
0.645 0.355 0.000
G46.7 Other lacunar syndromes
0.645 0.355 0.000
G95.0 Syringomyelia and syringobulbia
0.644 0.355 0.000
D21.5 Connective and other soft tissue of pelvis
0.643 0.357 0.000
S92.1 Fracture of talus
0.643 0.357 0.000
E53.9 Vitamin B deficiency, unspecified
0.643 0.357 0.000
E53.1 Pyridoxine deficiency
0.643 0.357 0.000
E53.0 Riboflavin deficiency
0.643 0.357 0.000
M22.0 Recurrent dislocation of patella
0.643 0.357 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.642 0.357 0.000
M22.9 Disorder of patella, unspecified
0.642 0.357 0.000
L27.9 Dermatitis due to unspecified substance taken internally
0.640 0.360 0.000
L27.8 Dermatitis due to other substances taken internally
0.640 0.360 0.000
L27.2 Dermatitis due to ingested food
0.640 0.360 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.640 0.360 0.000
S50.0 Contusion of elbow
0.639 0.361 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.639 0.361 0.000
C44.7 Skin of lower limb, including hip
0.639 0.361 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.639 0.361 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.638 0.362 0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents
0.638 0.362 0.000
M90 Osteopathies in diseases classified elsewhere
0.637 0.363 0.000
C71.9 Brain, unspecified
0.636 0.364 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.636 0.364 0.000
S98 Traumatic amputation of ankle and foot
0.636 0.364 0.000
S97 Crushing injury of ankle and foot
0.636 0.364 0.000
S95 Injury of blood vessels at ankle and foot level
0.636 0.364 0.000
S94 Injury of nerves at ankle and foot level
0.636 0.364 0.000
D55-D59 Haemolytic anaemias
0.635 0.364 0.000
G70-G73 Diseases of myoneural junction and muscle
0.634 0.366 0.000
M70-M79 Other soft tissue disorders
0.633 0.367 0.000
S56 Injury of muscle and tendon at forearm level
0.632 0.368 0.000
M45-M49 Spondylopathies
0.632 0.368 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.632 0.368 0.000
Y84.2 Radiological procedure and radiotherapy
0.632 0.368 0.000
L40-L45 Papulosquamous disorders
0.632 0.368 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.632 0.368 0.000
D44.3 Pituitary gland
0.631 0.368 0.000
T20 Burn and corrosion of head and neck
0.631 0.369 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.631 0.369 0.000
C66 Malignant neoplasm of ureter
0.631 0.369 0.000
G82 Paraplegia and tetraplegia
0.630 0.370 0.000
M21.4 Flat foot [pes planus] (acquired)
0.630 0.370 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.627 0.373 0.000
Y84.8 Other medical procedures
0.627 0.373 0.000
Y48.2 Other and unspecified general anaesthetics
0.626 0.374 0.000
D16 Benign neoplasm of bone and articular cartilage
0.626 0.374 0.000
Y58.0 BCG vaccine
0.626 0.374 0.000
G80 Infantile cerebral palsy
0.625 0.375 0.000
S92.4 Fracture of great toe
0.624 0.375 0.000
E85 Amyloidosis
0.624 0.376 0.000
S31 Open wound of abdomen, lower back and pelvis
0.623 0.376 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.623 0.376 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.623 0.377 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.623 0.377 0.000
L20 Atopic dermatitis
0.623 0.377 0.000
M67.0 Short Achilles tendon (acquired)
0.623 0.377 0.000
Y53.4 Other laxatives
0.623 0.377 0.000
C71.2 Temporal lobe
0.623 0.377 0.000
T31 Burns classified according to extent of body surface involved
0.622 0.378 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.622 0.378 0.000
T25 Burn and corrosion of ankle and foot
0.621 0.378 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.621 0.378 0.000
S99 Other and unspecified injuries of ankle and foot
0.621 0.379 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.621 0.379 0.000
B49 Unspecified mycosis
0.621 0.379 0.000
L98.0 Pyogenic granuloma
0.620 0.380 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.619 0.381 0.000
G95.1 Vascular myelopathies
0.619 0.381 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.618 0.382 0.000
G00 Bacterial meningitis, not elsewhere classified
0.618 0.382 0.000
M65.8 Other synovitis and tenosynovitis
0.618 0.382 0.000
S52.0 Fracture of upper end of ulna
0.618 0.382 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.617 0.382 0.000
Y46.4 Iminostilbenes
0.617 0.383 0.000
C45.9 Mesothelioma, unspecified
0.617 0.383 0.000
L91.0 Keloid scar
0.616 0.384 0.000
S52.10 Fracture of upper end of radius (closed)
0.616 0.384 0.000
S59 Other and unspecified injuries of forearm
0.616 0.384 0.000
S58 Traumatic amputation of forearm
0.616 0.384 0.000
S57 Crushing injury of forearm
0.616 0.384 0.000
S55 Injury of blood vessels at forearm level
0.616 0.384 0.000
S54 Injury of nerves at forearm level
0.616 0.384 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.616 0.384 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.615 0.385 0.000
S36 Injury of intra-abdominal organs
0.615 0.385 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.615 0.385 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.615 0.385 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.615 0.385 0.000
E84.9 Cystic fibrosis, unspecified
0.615 0.385 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.615 0.385 0.000
C71.8 Overlapping lesion of brain
0.614 0.386 0.000
B37.9 Candidiasis, unspecified
0.614 0.386 0.000
Y84.9 Medical procedure, unspecified
0.613 0.387 0.000
Y84.7 Blood-sampling
0.613 0.387 0.000
Y84.5 Insertion of gastric or duodenal sound
0.613 0.387 0.000
Y84.3 Shock therapy
0.613 0.387 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.613 0.387 0.000
M25.36 Other instability of joint (Lower leg)
0.613 0.387 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.612 0.388 0.000
C46 Kaposi's sarcoma
0.612 0.388 0.000
M25.50 Pain in joint (Multiple sites)
0.612 0.388 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.612 0.388 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.612 0.388 0.000
D10.1 Tongue
0.612 0.388 0.000
G31.0 Circumscribed brain atrophy
0.611 0.389 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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