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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78471656
log Bayes Factor = 30.7699
Chromosome 1   position 77,014,674  (GRCh37) Explore rs78471656 on Ensembl!
Variant rs78471656 is part of Cluster X0077

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
1.000 0.000 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.999 0.001 0.000
E78.0 Pure hypercholesterolaemia
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
R00 Abnormalities of heart beat
0.998 0.002 0.000
E10-E14 Diabetes mellitus
0.997 0.003 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.997 0.003 0.000
E11 Non-insulin-dependent diabetes mellitus
0.996 0.004 0.000
I20-I25 Ischaemic heart diseases
0.996 0.004 0.000
E11.9 Without complications
0.995 0.005 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.994 0.006 0.000
K80 Cholelithiasis
0.993 0.007 0.000
R00.2 Palpitations
0.992 0.008 0.000
Chapter VI Diseases of the nervous system
0.991 0.009 0.000
R02 Gangrene, not elsewhere classified
0.987 0.013 0.000
E65-E68 Obesity and other hyperalimentation
0.986 0.014 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.980 0.020 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.977 0.023 0.000
E66 Obesity
0.976 0.024 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.975 0.025 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.973 0.027 0.000
I51 Complications and ill-defined descriptions of heart disease
0.973 0.027 0.000
E66.9 Obesity, unspecified
0.972 0.028 0.000
K82 Other diseases of gallbladder
0.972 0.028 0.000
K83 Other diseases of biliary tract
0.966 0.034 0.000
N17-N19 Renal failure
0.965 0.035 0.000
N92 Excessive, frequent and irregular menstruation
0.964 0.036 0.000
L60-L75 Disorders of skin appendages
0.964 0.036 0.000
G90-G99 Other disorders of the nervous system
0.963 0.037 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.961 0.039 0.000
N94.6 Dysmenorrhoea, unspecified
0.959 0.041 0.000
N84 Polyp of female genital tract
0.959 0.041 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.957 0.043 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.955 0.045 0.000
E86 Volume depletion
0.952 0.048 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.952 0.048 0.000
R42 Dizziness and giddiness
0.952 0.048 0.000
L82 Seborrhoeic keratosis
0.946 0.054 0.000
I20 Angina pectoris
0.945 0.055 0.000
N60-N64 Disorders of breast
0.944 0.056 0.000
I44 Atrioventricular and left bundle-branch block
0.943 0.057 0.000
I25 Chronic ischaemic heart disease
0.942 0.058 0.000
N10-N16 Renal tubulo-interstitial diseases
0.939 0.061 0.000
R50-R69 General symptoms and signs
0.938 0.062 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.938 0.062 0.000
D50-D53 Nutritional anaemias
0.938 0.062 0.000
N93 Other abnormal uterine and vaginal bleeding
0.937 0.063 0.000
K70-K77 Diseases of liver
0.936 0.064 0.000
E78.5 Hyperlipidaemia, unspecified
0.931 0.069 0.000
E20-E35 Disorders of other endocrine glands
0.930 0.070 0.000
I10-I15 Hypertensive diseases
0.930 0.070 0.000
G20-G26 Extrapyramidal and movement disorders
0.928 0.072 0.000
I51.8 Other ill-defined heart diseases
0.927 0.073 0.000
D51 Vitamin B12 deficiency anaemia
0.924 0.076 0.000
Chapter VII Diseases of the eye and adnexa
0.923 0.077 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.923 0.077 0.000
N89 Other noninflammatory disorders of vagina
0.920 0.080 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.917 0.083 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.917 0.083 0.000
I35 Nonrheumatic aortic valve disorders
0.917 0.083 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.915 0.085 0.000
N19 Unspecified renal failure
0.915 0.085 0.000
I50 Heart failure
0.912 0.088 0.000
N13 Obstructive and reflux uropathy
0.911 0.089 0.000
K82.4 Cholesterolosis of gallbladder
0.906 0.094 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.903 0.097 0.000
Chapter I Certain infectious and parasitic diseases
0.902 0.098 0.000
I34 Nonrheumatic mitral valve disorders
0.900 0.100 0.000
I60-I69 Cerebrovascular diseases
0.900 0.100 0.000
R01 Cardiac murmurs and other cardiac sounds
0.893 0.107 0.000
N87 Dysplasia of cervix uteri
0.892 0.108 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.892 0.108 0.000
I44.2 Atrioventricular block, complete
0.889 0.111 0.000
I25.1 Atherosclerotic heart disease
0.889 0.111 0.000
N93.0 Postcoital and contact bleeding
0.887 0.113 0.000
H30-H36 Disorders of choroid and retina
0.884 0.116 0.000
R40 Somnolence, stupor and coma
0.881 0.119 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.881 0.119 0.000
N84.1 Polyp of cervix uteri
0.879 0.121 0.000
R51 Headache
0.878 0.122 0.000
L72.1 Trichilemmal cyst
0.877 0.123 0.000
N13.3 Other and unspecified hydronephrosis
0.876 0.124 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.875 0.125 0.000
Z88.5 Personal history of allergy to narcotic agent
0.875 0.125 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.873 0.127 0.000
R00.0 Tachycardia, unspecified
0.873 0.127 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.872 0.128 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.871 0.129 0.000
R53 Malaise and fatigue
0.871 0.129 0.000
B25-B34 Other viral diseases
0.870 0.130 0.000
I21 Acute myocardial infarction
0.867 0.133 0.000
L91 Hypertrophic disorders of skin
0.865 0.135 0.000
R07 Pain in throat and chest
0.863 0.137 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.859 0.141 0.000
K83.8 Other specified diseases of biliary tract
0.859 0.141 0.000
N60 Benign mammary dysplasia
0.855 0.145 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.853 0.147 0.000
H33 Retinal detachments and breaks
0.852 0.148 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.851 0.149 0.000
R47-R49 Symptoms and signs involving speech and voice
0.850 0.150 0.000
K83.1 Obstruction of bile duct
0.850 0.150 0.000
B34 Viral infection of unspecified site
0.848 0.152 0.000
N25-N29 Other disorders of kidney and ureter
0.847 0.153 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.847 0.153 0.000
K50-K52 Noninfective enteritis and colitis
0.846 0.154 0.000
G20 Parkinson's disease
0.846 0.154 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.842 0.158 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.841 0.159 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.841 0.159 0.000
Z75 Problems related to medical facilities and other health care
0.841 0.159 0.000
K86 Other diseases of pancreas
0.840 0.160 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.840 0.160 0.000
Z31 Procreative management
0.840 0.160 0.000
I20.0 Unstable angina
0.840 0.160 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.839 0.161 0.000
E11.4 With neurological complications
0.838 0.162 0.000
E11.3 With ophthalmic complications
0.838 0.162 0.000
L60 Nail disorders
0.837 0.163 0.000
I34.1 Mitral (valve) prolapse
0.835 0.164 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.834 0.166 0.000
I35.1 Aortic (valve) insufficiency
0.833 0.167 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.833 0.167 0.000
Z72 Problems related to lifestyle
0.832 0.168 0.000
B34.9 Viral infection, unspecified
0.832 0.168 0.000
I10 Essential (primary) hypertension
0.831 0.169 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.831 0.169 0.000
Z34 Supervision of normal pregnancy
0.830 0.169 0.000
R60 Oedema, not elsewhere classified
0.829 0.171 0.000
G93 Other disorders of brain
0.829 0.171 0.000
I21.9 Acute myocardial infarction, unspecified
0.829 0.171 0.000
I20.8 Other forms of angina pectoris
0.826 0.174 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.825 0.175 0.000
Z90.1 Acquired absence of breast(s)
0.823 0.177 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.822 0.178 0.000
K83.0 Cholangitis
0.822 0.178 0.000
R41.0 Disorientation, unspecified
0.821 0.179 0.000
H53-H54 Visual disturbances and blindness
0.819 0.181 0.000
H33.0 Retinal detachment with retinal break
0.819 0.181 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.817 0.183 0.000
I65.2 Occlusion and stenosis of carotid artery
0.817 0.183 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.816 0.184 0.000
Z97 Presence of other devices
0.816 0.184 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.815 0.185 0.000
Chapter V Mental and behavioural disorders
0.814 0.186 0.000
I50.1 Left ventricular failure
0.813 0.187 0.000
S70-S79 Injuries to the hip and thigh
0.812 0.188 0.000
Z94 Transplanted organ and tissue status
0.809 0.191 0.000
K74 Fibrosis and cirrhosis of liver
0.808 0.192 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.808 0.192 0.000
N18 Chronic renal failure
0.808 0.192 0.000
L89 Decubitus ulcer
0.806 0.194 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.804 0.196 0.000
N88 Other noninflammatory disorders of cervix uteri
0.804 0.196 0.000
I51.9 Heart disease, unspecified
0.803 0.197 0.000
Z73 Problems related to life-management difficulty
0.802 0.198 0.000
K82.2 Perforation of gallbladder
0.802 0.198 0.000
M65-M68 Disorders of synovium and tendon
0.801 0.199 0.000
R00.1 Bradycardia, unspecified
0.801 0.199 0.000
N84.0 Polyp of corpus uteri
0.800 0.200 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.799 0.201 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.798 0.202 0.000
Z33 Pregnant state, incidental
0.798 0.202 0.000
I44.0 Atrioventricular block, first degree
0.798 0.202 0.000
Z92 Personal history of medical treatment
0.797 0.203 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.797 0.203 0.000
I12 Hypertensive renal disease
0.796 0.204 0.000
R01.1 Cardiac murmur, unspecified
0.795 0.205 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.793 0.207 0.000
K75 Other inflammatory liver diseases
0.793 0.207 0.000
B35-B49 Mycoses
0.790 0.210 0.000
Z36 Antenatal screening
0.790 0.210 0.000
I51.7 Cardiomegaly
0.790 0.210 0.000
E78.4 Other hyperlipidaemia
0.788 0.212 0.000
R52 Pain, not elsewhere classified
0.788 0.212 0.000
I25.5 Ischaemic cardiomyopathy
0.786 0.214 0.000
G25 Other extrapyramidal and movement disorders
0.786 0.214 0.000
N92.3 Ovulation bleeding
0.786 0.214 0.000
S50-S59 Injuries to the elbow and forearm
0.785 0.215 0.000
N87.0 Mild cervical dysplasia
0.783 0.217 0.000
K35-K38 Diseases of appendix
0.783 0.217 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.780 0.220 0.000
I22 Subsequent myocardial infarction
0.780 0.220 0.000
Z88.0 Personal history of allergy to penicillin
0.779 0.221 0.000
N80 Endometriosis
0.779 0.221 0.000
I45 Other conduction disorders
0.778 0.222 0.000
Z95.2 Presence of prosthetic heart valve
0.777 0.223 0.000
Z95.4 Presence of other heart-valve replacement
0.777 0.223 0.000
Z89 Acquired absence of limb
0.777 0.223 0.000
K82.8 Other specified diseases of gallbladder
0.777 0.223 0.000
E11.1 With ketoacidosis
0.776 0.224 0.000
N61 Inflammatory disorders of breast
0.774 0.226 0.000
R40.0 Somnolence
0.774 0.226 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.773 0.227 0.000
N63 Unspecified lump in breast
0.773 0.227 0.000
E78.2 Mixed hyperlipidaemia
0.772 0.228 0.000
N84.3 Polyp of vulva
0.768 0.232 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.768 0.232 0.000
H35 Other retinal disorders
0.768 0.232 0.000
R45 Symptoms and signs involving emotional state
0.767 0.233 0.000
L65 Other nonscarring hair loss
0.766 0.234 0.000
G95 Other diseases of spinal cord
0.765 0.234 0.000
E23 Hypofunction and other disorders of pituitary gland
0.765 0.235 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.765 0.235 0.000
Z88.6 Personal history of allergy to analgesic agent
0.765 0.235 0.000
E27 Other disorders of adrenal gland
0.765 0.235 0.000
Z39 Postpartum care and examination
0.765 0.235 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.764 0.236 0.000
H43-H45 Disorders of vitreous body and globe
0.763 0.237 0.000
K85 Acute pancreatitis
0.762 0.238 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.761 0.239 0.000
E87.7 Fluid overload
0.759 0.241 0.000
Z72.0 Tobacco use
0.758 0.242 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.757 0.243 0.000
G91 Hydrocephalus
0.757 0.243 0.000
I38 Endocarditis, valve unspecified
0.755 0.245 0.000
G57 Mononeuropathies of lower limb
0.755 0.245 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.754 0.246 0.000
K82.9 Disease of gallbladder, unspecified
0.753 0.247 0.000
L81 Other disorders of pigmentation
0.753 0.247 0.000
K86.8 Other specified diseases of pancreas
0.753 0.247 0.000
G90 Disorders of autonomic nervous system
0.753 0.247 0.000
R07.4 Chest pain, unspecified
0.753 0.247 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.752 0.248 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.752 0.248 0.000
Z43 Attention to artificial openings
0.750 0.250 0.000
Z76 Persons encountering health services in other circumstances
0.750 0.250 0.000
G70-G73 Diseases of myoneural junction and muscle
0.750 0.250 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.750 0.250 0.000
Z32 Pregnancy examination and test
0.749 0.251 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.749 0.251 0.000
I05-I09 Chronic rheumatic heart diseases
0.748 0.252 0.000
I50.9 Heart failure, unspecified
0.746 0.254 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.746 0.254 0.000
R55 Syncope and collapse
0.745 0.255 0.000
K80.4 Calculus of bile duct with cholecystitis
0.745 0.255 0.000
Z31.2 In vitro fertilisation
0.745 0.255 0.000
M86-M90 Other osteopathies
0.745 0.255 0.000
K76 Other diseases of liver
0.744 0.255 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.744 0.256 0.000
A80-A89 Viral infections of the central nervous system
0.743 0.257 0.000
I25.3 Aneurysm of heart
0.743 0.257 0.000
K82.1 Hydrops of gallbladder
0.743 0.257 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.743 0.257 0.000
E22 Hyperfunction of pituitary gland
0.741 0.259 0.000
R07.2 Precordial pain
0.741 0.259 0.000
I30 Acute pericarditis
0.740 0.260 0.000
I31 Other diseases of pericardium
0.739 0.261 0.000
L91.8 Other hypertrophic disorders of skin
0.739 0.261 0.000
S90-S99 Injuries to the ankle and foot
0.739 0.261 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.738 0.262 0.000
R80 Isolated proteinuria
0.738 0.262 0.000
N80.9 Endometriosis, unspecified
0.737 0.263 0.000
I60 Subarachnoid haemorrhage
0.737 0.263 0.000
I24 Other acute ischaemic heart diseases
0.737 0.263 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.736 0.263 0.000
L84 Corns and callosities
0.736 0.264 0.000
N88.2 Stricture and stenosis of cervix uteri
0.736 0.264 0.000
K51 Ulcerative colitis
0.736 0.264 0.000
Z85 Personal history of malignant neoplasm
0.736 0.264 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.735 0.265 0.000
I26 Pulmonary embolism
0.733 0.267 0.000
N97 Female infertility
0.733 0.267 0.000
N94.1 Dyspareunia
0.733 0.267 0.000
Z12 Special screening examination for neoplasms
0.732 0.268 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.732 0.268 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.731 0.269 0.000
I35.9 Aortic valve disorder, unspecified
0.731 0.269 0.000
M15-M19 Arthrosis
0.730 0.270 0.000
I12.0 Hypertensive renal disease with renal failure
0.727 0.273 0.000
E88 Other metabolic disorders
0.727 0.273 0.000
Z04 Examination and observation for other reasons
0.726 0.274 0.000
H10-H13 Disorders of conjunctiva
0.725 0.275 0.000
N17 Acute renal failure
0.724 0.275 0.000
Chapter XXII Codes for special purposes
0.724 0.275 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.724 0.276 0.000
D52 Folate deficiency anaemia
0.724 0.276 0.000
Z92.3 Personal history of irradiation
0.723 0.277 0.000
Z99.3 Dependence on wheelchair
0.723 0.277 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.722 0.278 0.000
R79 Other abnormal findings of blood chemistry
0.722 0.278 0.000
N60.0 Solitary cyst of breast
0.721 0.279 0.000
I20.1 Angina pectoris with documented spasm
0.720 0.280 0.000
K72 Hepatic failure, not elsewhere classified
0.719 0.281 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.719 0.281 0.000
R60.1 Generalised oedema
0.719 0.281 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.718 0.282 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E85 Amyloidosis
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E73 Lactose intolerance
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.717 0.283 0.000
N91 Absent, scanty and rare menstruation
0.717 0.283 0.000
N82 Fistulae involving female genital tract
0.717 0.283 0.000
N96 Habitual aborter
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
E78.8 Other disorders of lipoprotein metabolism
0.717 0.283 0.000
E78.6 Lipoprotein deficiency
0.717 0.283 0.000
E78.3 Hyperchylomicronaemia
0.717 0.283 0.000
E78.1 Pure hyperglyceridaemia
0.717 0.283 0.000
N84.2 Polyp of vagina
0.716 0.284 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.716 0.284 0.000
N64 Other disorders of breast
0.716 0.284 0.000
M70-M79 Other soft tissue disorders
0.715 0.285 0.000
E13 Other specified diabetes mellitus
0.715 0.285 0.000
E12 Malnutrition-related diabetes mellitus
0.715 0.285 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.715 0.285 0.000
R46 Symptoms and signs involving appearance and behaviour
0.715 0.285 0.000
R43 Disturbances of smell and taste
0.715 0.285 0.000
E11.8 With unspecified complications
0.714 0.285 0.000
E11.7 With multiple complications
0.714 0.285 0.000
E11.6 With other specified complications
0.714 0.285 0.000
E11.0 With coma
0.714 0.285 0.000
L90 Atrophic disorders of skin
0.714 0.285 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.714 0.286 0.000
Q60-Q64 Congenital malformations of the urinary system
0.714 0.286 0.000
I23 Certain current complications following acute myocardial infarction
0.714 0.286 0.000
Z88.2 Personal history of allergy to sulphonamides
0.714 0.286 0.000
L10-L14 Bullous disorders
0.713 0.287 0.000
I47 Paroxysmal tachycardia
0.713 0.287 0.000
Z90.2 Acquired absence of lung [part of]
0.712 0.288 0.000
K80.3 Calculus of bile duct with cholangitis
0.712 0.288 0.000
N18.9 Chronic renal failure, unspecified
0.710 0.290 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.708 0.292 0.000
I33 Acute and subacute endocarditis
0.708 0.292 0.000
K50 Crohn's disease [regional enteritis]
0.708 0.292 0.000
E50-E64 Other nutritional deficiencies
0.707 0.293 0.000
E67 Other hyperalimentation
0.707 0.293 0.000
E68 Sequelae of hyperalimentation
0.707 0.293 0.000
E65 Localised adiposity
0.707 0.293 0.000
L91.0 Keloid scar
0.706 0.294 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.706 0.294 0.000
Z35 Supervision of high-risk pregnancy
0.705 0.295 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.705 0.295 0.000
R57 Shock, not elsewhere classified
0.704 0.296 0.000
S60-S69 Injuries to the wrist and hand
0.704 0.296 0.000
Z50 Care involving use of rehabilitation procedures
0.704 0.296 0.000
L50-L54 Urticaria and erythema
0.703 0.297 0.000
N95 Menopausal and other perimenopausal disorders
0.703 0.297 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.703 0.297 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.702 0.297 0.000
L94 Other localised connective tissue disorders
0.702 0.297 0.000
L93 Lupus erythematosus
0.702 0.297 0.000
L87 Transepidermal elimination disorders
0.702 0.297 0.000
L88 Pyoderma gangrenosum
0.702 0.297 0.000
L86 Keratoderma in diseases classified elsewhere
0.702 0.297 0.000
L83 Acanthosis nigricans
0.702 0.297 0.000
L80 Vitiligo
0.702 0.297 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.703 0.297 0.000
R49 Voice disturbances
0.702 0.298 0.000
R59 Enlarged lymph nodes
0.702 0.298 0.000
R07.1 Chest pain on breathing
0.701 0.299 0.000
Z84 Family history of other conditions
0.701 0.299 0.000
Z81 Family history of mental and behavioural disorders
0.701 0.299 0.000
Z02 Examination and encounter for administrative purposes
0.701 0.299 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.700 0.300 0.000
E66.1 Drug-induced obesity
0.700 0.300 0.000
E66.0 Obesity due to excess calories
0.700 0.300 0.000
H53 Visual disturbances
0.700 0.300 0.000
N92.5 Other specified irregular menstruation
0.700 0.300 0.000
M19 Other arthrosis
0.699 0.301 0.000
N94.5 Secondary dysmenorrhoea
0.699 0.301 0.000
N94.4 Primary dysmenorrhoea
0.699 0.301 0.000
N94.3 Premenstrual tension syndrome
0.699 0.301 0.000
N94.2 Vaginismus
0.699 0.301 0.000
N94.0 Mittelschmerz
0.699 0.301 0.000
N99-N99 Other disorders of the genitourinary system
0.699 0.301 0.000
I20.9 Angina pectoris, unspecified
0.699 0.301 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.698 0.302 0.000
I51.6 Cardiovascular disease, unspecified
0.698 0.302 0.000
I51.5 Myocardial degeneration
0.698 0.302 0.000
I51.4 Myocarditis, unspecified
0.698 0.302 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.698 0.302 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.698 0.302 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.698 0.302 0.000
I51.0 Cardiac septal defect, acquired
0.698 0.302 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.697 0.303 0.000
K82.3 Fistula of gallbladder
0.697 0.303 0.000
K82.0 Obstruction of gallbladder
0.697 0.303 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.696 0.303 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.696 0.304 0.000
R01.0 Benign and innocent cardiac murmurs
0.695 0.305 0.000
N60.1 Diffuse cystic mastopathy
0.695 0.305 0.000
N13.8 Other obstructive and reflux uropathy
0.694 0.306 0.000
M91-M94 Chondropathies
0.694 0.306 0.000
M40-M43 Deforming dorsopathies
0.694 0.306 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.693 0.307 0.000
K83.9 Disease of biliary tract, unspecified
0.692 0.308 0.000
K83.5 Biliary cyst
0.692 0.308 0.000
K83.4 Spasm of sphincter of Oddi
0.692 0.308 0.000
K83.3 Fistula of bile duct
0.692 0.308 0.000
K83.2 Perforation of bile duct
0.692 0.308 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.692 0.308 0.000
R41.3 Other amnesia
0.691 0.308 0.000
N92.4 Excessive bleeding in the premenopausal period
0.691 0.309 0.000
N92.2 Excessive menstruation at puberty
0.691 0.309 0.000
B37 Candidiasis
0.691 0.309 0.000
L75 Apocrine sweat disorders
0.691 0.309 0.000
L74 Eccrine sweat disorders
0.691 0.309 0.000
L73 Other follicular disorders
0.691 0.309 0.000
L70 Acne
0.691 0.309 0.000
L68 Hypertrichosis
0.691 0.309 0.000
L67 Hair colour and hair shaft abnormalities
0.691 0.309 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.691 0.309 0.000
L64 Androgenic alopecia
0.691 0.309 0.000
L63 Alopecia areata
0.691 0.309 0.000
L62 Nail disorders in diseases classified elsewhere
0.691 0.309 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.691 0.309 0.000
G96 Other disorders of central nervous system
0.690 0.310 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.690 0.310 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.690 0.310 0.000
G92 Toxic encephalopathy
0.690 0.310 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.690 0.310 0.000
S79 Other and unspecified injuries of hip and thigh
0.690 0.310 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.690 0.310 0.000
M67 Other disorders of synovium and tendon
0.690 0.310 0.000
L20-L30 Dermatitis and eczema
0.689 0.311 0.000
I46 Cardiac arrest
0.689 0.311 0.000
I63 Cerebral infarction
0.689 0.311 0.000
Z45 Adjustment and management of implanted device
0.689 0.311 0.000
R40.2 Coma, unspecified
0.688 0.312 0.000
N84.9 Polyp of female genital tract, unspecified
0.687 0.313 0.000
N84.8 Polyp of other parts of female genital tract
0.687 0.313 0.000
R60.0 Localised oedema
0.687 0.313 0.000
G40-G47 Episodic and paroxysmal disorders
0.687 0.313 0.000
K80.8 Other cholelithiasis
0.686 0.313 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.686 0.313 0.000
S52 Fracture of forearm
0.686 0.314 0.000
E80.4 Gilbert's syndrome
0.686 0.314 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.686 0.314 0.000
R52.1 Chronic intractable pain
0.686 0.314 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.685 0.315 0.000
I42 Cardiomyopathy
0.685 0.315 0.000
Z94.1 Heart transplant status
0.685 0.315 0.000
D55-D59 Haemolytic anaemias
0.684 0.315 0.000
R06 Abnormalities of breathing
0.684 0.316 0.000
Z38 Liveborn infants according to place of birth
0.683 0.317 0.000
N60.3 Fibrosclerosis of breast
0.682 0.318 0.000
G58 Other mononeuropathies
0.681 0.319 0.000
G30-G32 Other degenerative diseases of the nervous system
0.680 0.320 0.000
L60.0 Ingrowing nail
0.680 0.320 0.000
I69 Sequelae of cerebrovascular disease
0.680 0.320 0.000
H55-H59 Other disorders of eye and adnexa
0.680 0.320 0.000
D80-D89 Certain disorders involving the immune mechanism
0.679 0.321 0.000
Z46 Fitting and adjustment of other devices
0.678 0.322 0.000
Z90.3 Acquired absence of part of stomach
0.678 0.322 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.678 0.322 0.000
Z97.8 Presence of other specified devices
0.677 0.323 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.677 0.323 0.000
Z80 Family history of malignant neoplasm
0.677 0.323 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.677 0.323 0.000
I44.6 Other and unspecified fascicular block
0.676 0.324 0.000
I44.5 Left posterior fascicular block
0.676 0.324 0.000
I44.4 Left anterior fascicular block
0.676 0.324 0.000
I44.3 Other and unspecified atrioventricular block
0.676 0.324 0.000
R47 Speech disturbances, not elsewhere classified
0.676 0.324 0.000
Z95.0 Presence of cardiac pacemaker
0.676 0.324 0.000
I25.6 Silent myocardial ischaemia
0.675 0.324 0.000
I25.4 Coronary artery aneurysm
0.675 0.324 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.675 0.324 0.000
H54 Blindness and low vision
0.675 0.325 0.000
R68 Other general symptoms and signs
0.675 0.325 0.000
E11.5 With peripheral circulatory complications
0.674 0.325 0.000
N26 Unspecified contracted kidney
0.674 0.326 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.673 0.327 0.000
N15 Other renal tubulo-interstitial diseases
0.673 0.327 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.673 0.327 0.000
N11 Chronic tubulo-interstitial nephritis
0.673 0.327 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.673 0.327 0.000
R62 Lack of expected normal physiological development
0.673 0.327 0.000
R64 Cachexia
0.673 0.327 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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