TreeWAS – Variant ID: rs7849581

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I20-I25 Ischaemic heart diseases	0.000	0.795	0.205
I25 Chronic ischaemic heart disease	0.000	0.795	0.205
I20 Angina pectoris	0.000	0.799	0.201
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.800	0.200
I20.0 Unstable angina	0.000	0.812	0.188
I20.9 Angina pectoris, unspecified	0.000	0.817	0.183
I25.1 Atherosclerotic heart disease	0.000	0.818	0.182
I21 Acute myocardial infarction	0.000	0.821	0.179
I25.2 Old myocardial infarction	0.000	0.835	0.165
I21.9 Acute myocardial infarction, unspecified	0.000	0.841	0.159
I20.8 Other forms of angina pectoris	0.000	0.844	0.156
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.850	0.150
Chapter IX Diseases of the circulatory system	0.000	0.851	0.149
I24 Other acute ischaemic heart diseases	0.000	0.853	0.147
I23 Certain current complications following acute myocardial infarction	0.000	0.853	0.147
I22 Subsequent myocardial infarction	0.000	0.853	0.147
I25.6 Silent myocardial ischaemia	0.000	0.853	0.147
I25.4 Coronary artery aneurysm	0.000	0.853	0.147
I25.3 Aneurysm of heart	0.000	0.853	0.147
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.853	0.147
I20.1 Angina pectoris with documented spasm	0.000	0.855	0.145
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.859	0.141
I21.4 Acute subendocardial myocardial infarction	0.000	0.861	0.139
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.871	0.129
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.871	0.129
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.871	0.129
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.872	0.128
I10-I15 Hypertensive diseases	0.000	0.876	0.124
I25.5 Ischaemic cardiomyopathy	0.000	0.876	0.124
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.876	0.124
I77 Other disorders of arteries and arterioles	0.000	0.877	0.123
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.878	0.122
I73 Other peripheral vascular diseases	0.000	0.879	0.121
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.881	0.119
I10 Essential (primary) hypertension	0.000	0.886	0.114
I71 Aortic aneurysm and dissection	0.000	0.887	0.113
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.889	0.111
I77.1 Stricture of artery	0.000	0.889	0.111
I74 Arterial embolism and thrombosis	0.000	0.890	0.110
I00-I02 Acute rheumatic fever	0.000	0.893	0.107
I24.1 Dressler's syndrome	0.000	0.894	0.106
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.894	0.106
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.894	0.105
I22.8 Subsequent myocardial infarction of other sites	0.000	0.894	0.105
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.894	0.105
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.894	0.105
I23.8 Other current complications following acute myocardial infarction	0.000	0.894	0.105
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.894	0.105
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.894	0.105
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.894	0.105
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.894	0.105
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.894	0.105
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.894	0.105
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.894	0.105
I05-I09 Chronic rheumatic heart diseases	0.000	0.895	0.105
I73.9 Peripheral vascular disease, unspecified	0.000	0.896	0.104
I95 Hypotension	0.000	0.897	0.103
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.899	0.101
I72 Other aneurysm	0.000	0.899	0.101
I70 Atherosclerosis	0.000	0.899	0.101
I26 Pulmonary embolism	0.000	0.899	0.101
I24.8 Other forms of acute ischaemic heart disease	0.000	0.900	0.100
I95.1 Orthostatic hypotension	0.000	0.903	0.097
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.906	0.094
I73.0 Raynaud's syndrome	0.000	0.908	0.092
I15 Secondary hypertension	0.000	0.911	0.089
I13 Hypertensive heart and renal disease	0.000	0.911	0.089
I11 Hypertensive heart disease	0.000	0.911	0.089
I78 Diseases of capillaries	0.000	0.911	0.089
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.911	0.089
I77.8 Other specified disorders of arteries and arterioles	0.000	0.911	0.089
I77.6 Arteritis, unspecified	0.000	0.911	0.089
I77.5 Necrosis of artery	0.000	0.911	0.089
I77.4 Coeliac artery compression syndrome	0.000	0.911	0.089
I77.3 Arterial fibromuscular dysplasia	0.000	0.911	0.089
I77.2 Rupture of artery	0.000	0.911	0.089
I77.0 Arteriovenous fistula, acquired	0.000	0.911	0.089
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.912	0.088
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.912	0.088
I99 Other and unspecified disorders of circulatory system	0.000	0.912	0.088
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.912	0.088
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.913	0.087
I73.8 Other specified peripheral vascular diseases	0.000	0.913	0.087
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.913	0.087
I28 Other diseases of pulmonary vessels	0.000	0.914	0.086
I30-I52 Other forms of heart disease	0.000	0.916	0.084
I27 Other pulmonary heart diseases	0.000	0.918	0.082
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.918	0.081
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.918	0.081
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.918	0.081
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.918	0.081
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.918	0.081
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.918	0.081
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.918	0.081
I71.0 Dissection of aorta [any part]	0.000	0.918	0.081
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.921	0.079
I74.8 Embolism and thrombosis of other arteries	0.000	0.921	0.079
I74.5 Embolism and thrombosis of iliac artery	0.000	0.921	0.079
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.921	0.079
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.921	0.079
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.921	0.079
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.921	0.079
I51 Complications and ill-defined descriptions of heart disease	0.000	0.921	0.079
I08 Multiple valve diseases	0.000	0.923	0.077
I02 Rheumatic chorea	0.000	0.923	0.077
I01 Rheumatic fever with heart involvement	0.000	0.923	0.077
I00 Rheumatic fever without mention of heart involvement	0.000	0.923	0.077
I09 Other rheumatic heart diseases	0.000	0.924	0.076
I06 Rheumatic aortic valve diseases	0.000	0.924	0.076
I05 Rheumatic mitral valve diseases	0.000	0.924	0.076
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.926	0.074
I95.8 Other hypotension	0.000	0.926	0.074
I95.0 Idiopathic hypotension	0.000	0.926	0.074
I60-I69 Cerebrovascular diseases	0.000	0.927	0.073
Y83.8 Other surgical procedures	0.000	0.927	0.073
I70.9 Generalised and unspecified atherosclerosis	0.000	0.927	0.073
I70.8 Atherosclerosis of other arteries	0.000	0.927	0.073
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.927	0.073
I70.1 Atherosclerosis of renal artery	0.000	0.927	0.073
I70.0 Atherosclerosis of aorta	0.000	0.927	0.073
I72.9 Aneurysm of unspecified site	0.000	0.927	0.073
I72.8 Aneurysm of other specified arteries	0.000	0.927	0.073
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.927	0.073
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.927	0.073
I72.4 Aneurysm of artery of lower extremity	0.000	0.927	0.073
I72.3 Aneurysm of iliac artery	0.000	0.927	0.073
I72.2 Aneurysm of renal artery	0.000	0.927	0.073
I72.1 Aneurysm of artery of upper extremity	0.000	0.927	0.073
I72.0 Aneurysm of carotid artery	0.000	0.927	0.073
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.927	0.073
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.927	0.073
I79.1 Aortitis in diseases classified elsewhere	0.000	0.927	0.073
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.927	0.073
I07 Rheumatic tricuspid valve diseases	0.000	0.927	0.072
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.928	0.072
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.929	0.071
Y83.1 Surgical operation with implant of artificial internal device	0.000	0.930	0.070
I51.8 Other ill-defined heart diseases	0.000	0.930	0.070
I47 Paroxysmal tachycardia	0.000	0.931	0.069
I12 Hypertensive renal disease	0.000	0.931	0.069
I51.7 Cardiomegaly	0.000	0.932	0.068
I95.9 Hypotension, unspecified	0.000	0.933	0.067
I50 Heart failure	0.000	0.936	0.064
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.936	0.064
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.936	0.064
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.936	0.064
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.936	0.064
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.936	0.064
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.936	0.064
I15.9 Seconday hypertension, unspecified	0.000	0.936	0.064
I15.8 Other secondary hypertension	0.000	0.936	0.064
I15.2 Hypertension secondary to endocrine disorders	0.000	0.936	0.064
I15.1 Hypertension secondary to other renal disorders	0.000	0.936	0.064
I15.0 Renovascular hypertension	0.000	0.936	0.064
I78.9 Disease of capillaries, unspecified	0.000	0.936	0.064
I78.8 Other diseases of capillaries	0.000	0.936	0.064
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.936	0.064
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.937	0.063
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.937	0.063
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.937	0.063
I97.1 Other functional disturbances following cardiac surgery	0.000	0.937	0.063
I97.0 Postcardiotomy syndrome	0.000	0.937	0.063
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.937	0.063
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.937	0.063
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.937	0.063
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.937	0.063
I98.0 Cardiovascular syphilis	0.000	0.937	0.063
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.938	0.062
I28.8 Other specified diseases of pulmonary vessels	0.000	0.938	0.062
I28.1 Aneurysm of pulmonary artery	0.000	0.938	0.062
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.938	0.062
I46 Cardiac arrest	0.000	0.939	0.061
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.940	0.060
I52 Other heart disorders in diseases classified elsewhere	0.000	0.940	0.060
I48 Atrial fibrillation and flutter	0.000	0.940	0.060
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.940	0.060
I41 Myocarditis in diseases classified elsewhere	0.000	0.940	0.060
I40 Acute myocarditis	0.000	0.940	0.060
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.940	0.060
I37 Pulmonary valve disorders	0.000	0.940	0.060
I36 Nonrheumatic tricuspid valve disorders	0.000	0.940	0.060
I32 Pericarditis in diseases classified elsewhere	0.000	0.940	0.060
I30 Acute pericarditis	0.000	0.940	0.060
I08.0 Disorders of both mitral and aortic valves	0.000	0.940	0.060
I51.9 Heart disease, unspecified	0.000	0.940	0.060
I31 Other diseases of pericardium	0.000	0.941	0.059
I27.9 Pulmonary heart disease, unspecified	0.000	0.941	0.059
I27.8 Other specified pulmonary heart diseases	0.000	0.941	0.059
I27.1 Kyphoscoliotic heart disease	0.000	0.941	0.059
I27.0 Primary pulmonary hypertension	0.000	0.941	0.059
I35 Nonrheumatic aortic valve disorders	0.000	0.941	0.059
I38 Endocarditis, valve unspecified	0.000	0.941	0.058
I95.2 Hypotension due to drugs	0.000	0.942	0.058
I45 Other conduction disorders	0.000	0.943	0.057
I47.1 Supraventricular tachycardia	0.000	0.943	0.057
I51.6 Cardiovascular disease, unspecified	0.000	0.943	0.057
I51.5 Myocardial degeneration	0.000	0.943	0.057
I51.4 Myocarditis, unspecified	0.000	0.943	0.057
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.943	0.057
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.943	0.057
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.943	0.057
I51.0 Cardiac septal defect, acquired	0.000	0.943	0.057
I85 Oesophageal varices	0.000	0.944	0.056
Y83.2 Surgical operation with anastomosis, bypass or graft	0.000	0.944	0.056
Y83.6 Removal of other organ (partial) (total)	0.000	0.944	0.056
I08.9 Multiple valve disease, unspecified	0.000	0.944	0.056
I08.8 Other multiple valve diseases	0.000	0.944	0.056
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.944	0.056
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.944	0.056
I27.2 Other secondary pulmonary hypertension	0.000	0.945	0.055
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.945	0.055
I01.8 Other acute rheumatic heart disease	0.000	0.945	0.055
I01.2 Acute rheumatic myocarditis	0.000	0.945	0.055
I01.1 Acute rheumatic endocarditis	0.000	0.945	0.055
I01.0 Acute rheumatic pericarditis	0.000	0.945	0.055
I02.9 Rheumatic chorea without heart involvement	0.000	0.945	0.055
I02.0 Rheumatic chorea with heart involvement	0.000	0.945	0.055
I05.9 Mitral valve disease, unspecified	0.000	0.945	0.054
I05.8 Other mitral valve diseases	0.000	0.945	0.054
I05.2 Mitral stenosis with insufficiency	0.000	0.945	0.054
I05.1 Rheumatic mitral insufficiency	0.000	0.945	0.054
I05.0 Mitral stenosis	0.000	0.945	0.054
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.945	0.054
I06.8 Other rheumatic aortic valve diseases	0.000	0.945	0.054
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.945	0.054
I06.1 Rheumatic aortic insufficiency	0.000	0.945	0.054
I06.0 Rheumatic aortic stenosis	0.000	0.945	0.054
I09.9 Rheumatic heart disease, unspecified	0.000	0.945	0.054
I09.8 Other specified rheumatic heart diseases	0.000	0.945	0.054
I09.2 Chronic rheumatic pericarditis	0.000	0.945	0.054
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.945	0.054
I09.0 Rheumatic myocarditis	0.000	0.945	0.054
I33 Acute and subacute endocarditis	0.000	0.946	0.054
I84 Haemorrhoids	0.000	0.946	0.054
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.946	0.053
I88 Nonspecific lymphadenitis	0.000	0.946	0.053
I87 Other disorders of veins	0.000	0.946	0.053
I86 Varicose veins of other sites	0.000	0.946	0.053
I82 Other venous embolism and thrombosis	0.000	0.946	0.053
I81 Portal vein thrombosis	0.000	0.946	0.053
I47.2 Ventricular tachycardia	0.000	0.946	0.053
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.947	0.053
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.947	0.053
I62 Other nontraumatic intracranial haemorrhage	0.000	0.947	0.053
I60 Subarachnoid haemorrhage	0.000	0.947	0.053
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.948	0.052
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.948	0.052
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.948	0.052
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.948	0.052
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.948	0.052
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.948	0.052
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.948	0.052
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.948	0.052
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.948	0.052
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.948	0.052
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.948	0.052
I07.9 Tricuspid valve disease, unspecified	0.000	0.948	0.052
I07.8 Other tricuspid valve diseases	0.000	0.948	0.052
I07.2 Tricuspid stenosis with insufficiency	0.000	0.948	0.052
I07.0 Tricuspid stenosis	0.000	0.948	0.052
I69 Sequelae of cerebrovascular disease	0.000	0.948	0.052
I78.1 Naevus, nonneoplastic	0.000	0.948	0.051
I65.2 Occlusion and stenosis of carotid artery	0.000	0.949	0.051
Y83.9 Surgical procedure, unspecified	0.000	0.949	0.051
Y83.5 Amputation of limb(s)	0.000	0.949	0.051
Y83.0 Surgical operation with transplant of whole organ	0.000	0.949	0.051
Y83.3 Surgical operation with formation of external stoma	0.000	0.949	0.051
I50.0 Congestive heart failure	0.000	0.949	0.051
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.950	0.050
I47.0 Reentry ventricular arrhythmia	0.000	0.950	0.050
I07.1 Tricuspid insufficiency	0.000	0.951	0.049
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.951	0.049
I61 Intracerebral haemorrhage	0.000	0.952	0.048
I50.1 Left ventricular failure	0.000	0.952	0.048
I35.1 Aortic (valve) insufficiency	0.000	0.953	0.047
I84.8 Unspecified haemorrhoids with other complications	0.000	0.953	0.047
I12.9 Hypertensive renal disease without renal failure	0.000	0.955	0.045
I63 Cerebral infarction	0.000	0.955	0.045
I50.9 Heart failure, unspecified	0.000	0.955	0.045
I31.9 Disease of pericardium, unspecified	0.000	0.955	0.044
I46.0 Cardiac arrest with successful resuscitation	0.000	0.956	0.044
I84.5 External haemorrhoids without complication	0.000	0.956	0.044
I46.9 Cardiac arrest, unspecified	0.000	0.956	0.044
I46.1 Sudden cardiac death, so described	0.000	0.956	0.044
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.956	0.043
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.956	0.043
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.956	0.043
I65.1 Occlusion and stenosis of basilar artery	0.000	0.956	0.043
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.956	0.043
I30.9 Acute pericarditis, unspecified	0.000	0.957	0.043
I30.8 Other forms of acute pericarditis	0.000	0.957	0.043
I30.1 Infective pericarditis	0.000	0.957	0.043
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.957	0.043
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.957	0.043
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.957	0.043
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.957	0.043
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.957	0.043
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.957	0.043
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.957	0.043
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.957	0.043
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.957	0.043
I37.9 Pulmonary valve disorder, unspecified	0.000	0.957	0.043
I37.8 Other pulmonary valve disorders	0.000	0.957	0.043
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.957	0.043
I37.1 Pulmonary valve insufficiency	0.000	0.957	0.043
I37.0 Pulmonary valve stenosis	0.000	0.957	0.043
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.957	0.043
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.957	0.043
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.957	0.043
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.957	0.043
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.957	0.043
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.957	0.043
I40.9 Acute myocarditis, unspecified	0.000	0.957	0.043
I40.8 Other acute myocarditis	0.000	0.957	0.043
I40.1 Isolated myocarditis	0.000	0.957	0.043
I40.0 Infective myocarditis	0.000	0.957	0.043
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.957	0.043
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.957	0.043
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.957	0.043
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.957	0.043
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.957	0.043
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.957	0.043
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.957	0.043
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.957	0.043
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.957	0.043
I48.4 Atypical atrial flutter	0.000	0.957	0.043
I48.3 Typical atrial flutter	0.000	0.957	0.043
I48.2 Chronic atrial fibrillation	0.000	0.957	0.043
I48.1 Persistent atrial fibrillation	0.000	0.957	0.043
I48.0 Paroxysmal atrial fibrillation	0.000	0.957	0.043
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.957	0.043
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.957	0.043
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.957	0.043
I85.9 Oesophageal varices without bleeding	0.000	0.957	0.043
I84.1 Internal haemorrhoids with other complications	0.000	0.957	0.043
I31.8 Other specified diseases of pericardium	0.000	0.957	0.043
I31.2 Haemopericardium, not elsewhere classified	0.000	0.957	0.043
I31.1 Chronic constrictive pericarditis	0.000	0.957	0.043
I31.0 Chronic adhesive pericarditis	0.000	0.957	0.043
I42 Cardiomyopathy	0.000	0.957	0.042
I44 Atrioventricular and left bundle-branch block	0.000	0.957	0.042
I35.9 Aortic valve disorder, unspecified	0.000	0.957	0.042
I35.8 Other aortic valve disorders	0.000	0.957	0.042
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.958	0.042
I45.9 Conduction disorder, unspecified	0.000	0.959	0.041
I45.8 Other specified conduction disorders	0.000	0.959	0.041
I45.6 Preexcitation syndrome	0.000	0.959	0.041
I45.5 Other specified heart block	0.000	0.959	0.041
I45.4 Nonspecific intraventricular block	0.000	0.959	0.041
I45.3 Trifascicular block	0.000	0.959	0.041
I45.2 Bifascicular block	0.000	0.959	0.041
I45.0 Right fascicular block	0.000	0.959	0.041
I49 Other cardiac arrhythmias	0.001	0.959	0.040
I85.0 Oesophageal varices with bleeding	0.000	0.959	0.040
I83 Varicose veins of lower extremities	0.000	0.960	0.040
I31.3 Pericardial effusion (noninflammatory)	0.000	0.960	0.040
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.961	0.039
I34 Nonrheumatic mitral valve disorders	0.000	0.961	0.039
I33.9 Acute endocarditis, unspecified	0.000	0.961	0.039
I84.7 Unspecified thrombosed haemorrhoids	0.000	0.961	0.039
I84.4 External haemorrhoids with other complications	0.000	0.961	0.039
I84.3 External thrombosed haemorrhoids	0.000	0.961	0.039
I84.0 Internal thrombosed haemorrhoids	0.000	0.961	0.039
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.961	0.038
I82.8 Embolism and thrombosis of other specified veins	0.000	0.961	0.038
I82.3 Embolism and thrombosis of renal vein	0.000	0.961	0.038
I82.2 Embolism and thrombosis of vena cava	0.000	0.961	0.038
I82.1 Thrombophlebitis migrans	0.000	0.961	0.038
I82.0 Budd-Chiari syndrome	0.000	0.961	0.038
I86.8 Varicose veins of other specified sites	0.000	0.961	0.038
I86.4 Gastric varices	0.000	0.961	0.038
I86.3 Vulval varices	0.000	0.961	0.038
I86.2 Pelvic varices	0.000	0.961	0.038
I86.1 Scrotal varices	0.000	0.961	0.038
I86.0 Sublingual varices	0.000	0.961	0.038
I87.9 Disorder of vein, unspecified	0.000	0.961	0.038
I87.8 Other specified disorders of veins	0.000	0.961	0.038
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.961	0.038
I87.1 Compression of vein	0.000	0.961	0.038
I87.0 Postphlebitic syndrome	0.000	0.961	0.038
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.961	0.038
I88.8 Other nonspecific lymphadenitis	0.000	0.961	0.038
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.961	0.038
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.961	0.038
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.961	0.038
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.961	0.038
I89.1 Lymphangitis	0.000	0.961	0.038
I89.0 Lymphoedema, not elsewhere classified	0.000	0.961	0.038
Y83.4 Other reconstructive surgery	0.000	0.961	0.038
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.962	0.038
I60.8 Other subarachnoid haemorrhage	0.000	0.962	0.038
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.962	0.038
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.962	0.038
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.962	0.038
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.962	0.038
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.962	0.038
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.962	0.038
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.962	0.038
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.962	0.038
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.962	0.038
I62.1 Nontraumatic extradural haemorrhage	0.000	0.962	0.038
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.962	0.038
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.962	0.038
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.962	0.038
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.962	0.038
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.962	0.038
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.962	0.038
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.962	0.038
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.962	0.038
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.962	0.038
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.962	0.038
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.962	0.038
I68.0 Cerebral amyloid angiopathy	0.000	0.962	0.038
I35.0 Aortic (valve) stenosis	0.000	0.962	0.038
I45.1 Other and unspecified right bundle-branch block	0.000	0.962	0.037
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.963	0.037
I69.3 Sequelae of cerebral infarction	0.000	0.963	0.037
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.963	0.037
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.963	0.037
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.963	0.037
I12.0 Hypertensive renal disease with renal failure	0.000	0.963	0.037
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.964	0.036
G56.0 Carpal tunnel syndrome	0.000	0.964	0.036
I80 Phlebitis and thrombophlebitis	0.000	0.964	0.036
I61.8 Other intracerebral haemorrhage	0.000	0.965	0.034
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.965	0.034
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.965	0.034
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.965	0.034
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.965	0.034
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.965	0.034
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.965	0.034
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.965	0.034
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.966	0.034
I33.0 Acute and subacute infective endocarditis	0.000	0.967	0.033
I67 Other cerebrovascular diseases	0.000	0.967	0.033
I63.8 Other cerebral infarction	0.000	0.967	0.032
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.967	0.032
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.967	0.032
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.967	0.032
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.967	0.032
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.967	0.032
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.967	0.032
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.968	0.032
G56 Mononeuropathies of upper limb	0.000	0.969	0.031
I42.8 Other cardiomyopathies	0.000	0.969	0.031
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.969	0.031
I42.6 Alcoholic cardiomyopathy	0.000	0.969	0.031
I42.5 Other restrictive cardiomyopathy	0.000	0.969	0.031
I42.4 Endocardial fibroelastosis	0.000	0.969	0.031
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.969	0.031
I42.2 Other hypertrophic cardiomyopathy	0.000	0.969	0.031
I44.6 Other and unspecified fascicular block	0.000	0.969	0.031
I44.5 Left posterior fascicular block	0.000	0.969	0.031
I44.4 Left anterior fascicular block	0.000	0.969	0.031
I44.3 Other and unspecified atrioventricular block	0.000	0.969	0.031
I44.1 Atrioventricular block, second degree	0.000	0.969	0.031
I84.9 Unspecified haemorrhoids without complication	0.000	0.969	0.031
I49.3 Ventricular premature depolarisation	0.000	0.969	0.030
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.970	0.029
I49.4 Other and unspecified premature depolarisation	0.001	0.971	0.029
I49.2 Junctional premature depolarisation	0.001	0.971	0.029
I49.1 Atrial premature depolarisation	0.001	0.971	0.029
I49.0 Ventricular fibrillation and flutter	0.001	0.971	0.029
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.971	0.029
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.971	0.029
I42.0 Dilated cardiomyopathy	0.000	0.971	0.029
I44.2 Atrioventricular block, complete	0.000	0.971	0.029
I84.2 Internal haemorrhoids without complication	0.000	0.971	0.029
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.971	0.028
I84.6 Residual haemorrhoidal skin tags	0.000	0.972	0.028
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.972	0.028
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.972	0.028
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.972	0.028
I44.7 Left bundle-branch block, unspecified	0.000	0.972	0.028
Y84.8 Other medical procedures	0.000	0.972	0.028
G50-G59 Nerve, nerve root and plexus disorders	0.000	0.972	0.028
I49.9 Cardiac arrhythmia, unspecified	0.000	0.972	0.027
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.000	0.973	0.027
I49.8 Other specified cardiac arrhythmias	0.001	0.973	0.026
I42.9 Cardiomyopathy, unspecified	0.001	0.974	0.026
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.000	0.974	0.026
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.974	0.026
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.974	0.026
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.974	0.026
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.974	0.026
I34.1 Mitral (valve) prolapse	0.001	0.975	0.025
I63.9 Cerebral infarction, unspecified	0.000	0.975	0.025
I42.1 Obstructive hypertrophic cardiomyopathy	0.001	0.975	0.024
Y84.9 Medical procedure, unspecified	0.000	0.975	0.024
Y84.7 Blood-sampling	0.000	0.975	0.024
Y84.5 Insertion of gastric or duodenal sound	0.000	0.975	0.024
Y84.4 Aspiration of fluid	0.000	0.975	0.024
Y84.3 Shock therapy	0.000	0.975	0.024
Y84.2 Radiological procedure and radiotherapy	0.000	0.975	0.024
Y84.1 Kidney dialysis	0.000	0.975	0.024
Y84.0 Cardiac catheterisation	0.000	0.975	0.024
Y84.6 Urinary catheterisation	0.000	0.975	0.024
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.976	0.024
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.976	0.024
I67.5 Moyamoya disease	0.000	0.976	0.024

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations