TreeWAS – Variant ID: rs7853989

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	1.000	0.000	0.000
I80 Phlebitis and thrombophlebitis	0.999	0.001	0.000
I84 Haemorrhoids	0.000	0.005	0.995
I84.9 Unspecified haemorrhoids without complication	0.000	0.006	0.994
I84.5 External haemorrhoids without complication	0.000	0.013	0.987
I84.1 Internal haemorrhoids with other complications	0.000	0.029	0.971
I84.8 Unspecified haemorrhoids with other complications	0.000	0.031	0.969
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.959	0.041	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.934	0.066	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.900	0.100	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.883	0.115	0.002
I83 Varicose veins of lower extremities	0.855	0.145	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.849	0.151	0.000
I84.4 External haemorrhoids with other complications	0.000	0.155	0.845
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.816	0.184	0.000
I82 Other venous embolism and thrombosis	0.775	0.225	0.001
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.756	0.244	0.000
I84.3 External thrombosed haemorrhoids	0.000	0.246	0.754
I83.1 Varicose veins of lower extremities with inflammation	0.737	0.263	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.000	0.271	0.729
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.724	0.276	0.000
I84.0 Internal thrombosed haemorrhoids	0.000	0.279	0.721
I86 Varicose veins of other sites	0.709	0.290	0.001
I84.2 Internal haemorrhoids without complication	0.000	0.309	0.691
I82.8 Embolism and thrombosis of other specified veins	0.672	0.328	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.667	0.333	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.649	0.351	0.000
I81 Portal vein thrombosis	0.644	0.355	0.001
I85 Oesophageal varices	0.610	0.389	0.001
I86.4 Gastric varices	0.592	0.408	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.000	0.409	0.591
I88 Nonspecific lymphadenitis	0.577	0.421	0.002
I82.3 Embolism and thrombosis of renal vein	0.555	0.444	0.001
I82.1 Thrombophlebitis migrans	0.555	0.444	0.001
I82.0 Budd-Chiari syndrome	0.555	0.444	0.001
I86.8 Varicose veins of other specified sites	0.521	0.479	0.001
I87 Other disorders of veins	0.512	0.486	0.001
I86.3 Vulval varices	0.508	0.491	0.001
I86.2 Pelvic varices	0.508	0.491	0.001
I86.0 Sublingual varices	0.508	0.491	0.001
I82.2 Embolism and thrombosis of vena cava	0.486	0.513	0.001
I86.1 Scrotal varices	0.481	0.519	0.001
I85.9 Oesophageal varices without bleeding	0.449	0.551	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.428	0.570	0.002
I88.8 Other nonspecific lymphadenitis	0.414	0.585	0.001
I88.1 Chronic lymphadenitis, except mesenteric	0.414	0.585	0.001
I88.0 Nonspecific mesenteric lymphadenitis	0.414	0.585	0.001
I85.0 Oesophageal varices with bleeding	0.402	0.597	0.001
I87.9 Disorder of vein, unspecified	0.367	0.632	0.001
I87.0 Postphlebitic syndrome	0.367	0.632	0.001
I88.9 Nonspecific lymphadenitis, unspecified	0.358	0.640	0.002
I87.1 Compression of vein	0.355	0.644	0.001
I87.2 Venous insufficiency (chronic) (peripheral)	0.328	0.671	0.001
I87.8 Other specified disorders of veins	0.319	0.680	0.001
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.307	0.692	0.001
D12.8 Rectum	0.000	0.692	0.308
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.000	0.703	0.297
D12.5 Sigmoid colon	0.000	0.708	0.292
D12.6 Colon, unspecified	0.000	0.713	0.287
I84.6 Residual haemorrhoidal skin tags	0.000	0.715	0.285
I89.0 Lymphoedema, not elsewhere classified	0.274	0.725	0.001
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.264	0.735	0.001
D12.2 Ascending colon	0.000	0.746	0.254
D12.0 Caecum	0.000	0.753	0.247
I89.1 Lymphangitis	0.239	0.759	0.002
Z86.7 Personal history of diseases of the circulatory system	0.233	0.767	0.000
D12.7 Rectosigmoid junction	0.000	0.783	0.216
D12.1 Appendix	0.000	0.803	0.197
Chapter IX Diseases of the circulatory system	0.191	0.809	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.187	0.813	0.000
I26 Pulmonary embolism	0.185	0.815	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.184	0.816	0.000
D12.9 Anus and anal canal	0.000	0.824	0.176
I70-I79 Diseases of arteries, arterioles and capillaries	0.171	0.829	0.000
I74 Arterial embolism and thrombosis	0.166	0.834	0.000
I77 Other disorders of arteries and arterioles	0.151	0.849	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.851	0.149
D64.9 Anaemia, unspecified	0.000	0.857	0.143
I74.9 Embolism and thrombosis of unspecified artery	0.143	0.857	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.142	0.858	0.000
K57 Diverticular disease of intestine	0.000	0.858	0.142
I74.5 Embolism and thrombosis of iliac artery	0.139	0.861	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.000	0.862	0.138
I28 Other diseases of pulmonary vessels	0.138	0.862	0.000
I00-I02 Acute rheumatic fever	0.137	0.863	0.000
I78 Diseases of capillaries	0.136	0.864	0.000
I27 Other pulmonary heart diseases	0.135	0.865	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.135	0.865	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.134	0.866	0.000
I77.6 Arteritis, unspecified	0.125	0.875	0.000
I77.0 Arteriovenous fistula, acquired	0.125	0.875	0.000
D12.4 Descending colon	0.000	0.875	0.125
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.000	0.876	0.124
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.123	0.876	0.000
I72 Other aneurysm	0.123	0.877	0.000
I77.8 Other specified disorders of arteries and arterioles	0.122	0.878	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.000	0.878	0.122
I74.8 Embolism and thrombosis of other arteries	0.119	0.881	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.119	0.881	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.119	0.881	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.119	0.881	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.119	0.881	0.000
I20-I25 Ischaemic heart diseases	0.118	0.882	0.000
I78.1 Naevus, nonneoplastic	0.116	0.884	0.000
I24 Other acute ischaemic heart diseases	0.111	0.889	0.000
D12.3 Transverse colon	0.000	0.892	0.108
I77.5 Necrosis of artery	0.108	0.892	0.000
I77.4 Coeliac artery compression syndrome	0.108	0.892	0.000
I77.3 Arterial fibromuscular dysplasia	0.108	0.892	0.000
I77.2 Rupture of artery	0.108	0.892	0.000
I24.8 Other forms of acute ischaemic heart disease	0.103	0.897	0.000
I28.8 Other specified diseases of pulmonary vessels	0.103	0.897	0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.000	0.898	0.102
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.000	0.898	0.102
I27.2 Other secondary pulmonary hypertension	0.102	0.898	0.000
I27.0 Primary pulmonary hypertension	0.101	0.899	0.000
I70 Atherosclerosis	0.100	0.899	0.000
I72.0 Aneurysm of carotid artery	0.099	0.901	0.000
K57.0 Diverticular disease of small intestine with perforation and abscess	0.000	0.901	0.099
I72.4 Aneurysm of artery of lower extremity	0.099	0.901	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.099	0.901	0.000
I28.1 Aneurysm of pulmonary artery	0.099	0.901	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.099	0.901	0.000
I02 Rheumatic chorea	0.098	0.902	0.000
I01 Rheumatic fever with heart involvement	0.098	0.902	0.000
I00 Rheumatic fever without mention of heart involvement	0.098	0.902	0.000
I78.9 Disease of capillaries, unspecified	0.097	0.903	0.000
I78.8 Other diseases of capillaries	0.097	0.903	0.000
I27.1 Kyphoscoliotic heart disease	0.097	0.903	0.000
I27.9 Pulmonary heart disease, unspecified	0.097	0.903	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.095	0.905	0.000
I22 Subsequent myocardial infarction	0.093	0.907	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.907	0.093
I24.1 Dressler's syndrome	0.091	0.909	0.000
I27.8 Other specified pulmonary heart diseases	0.090	0.910	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.089	0.910	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.089	0.911	0.000
I79.1 Aortitis in diseases classified elsewhere	0.089	0.911	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.089	0.911	0.000
I72.9 Aneurysm of unspecified site	0.089	0.911	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.089	0.911	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.089	0.911	0.000
I72.2 Aneurysm of renal artery	0.089	0.911	0.000
I72.1 Aneurysm of artery of upper extremity	0.089	0.911	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.087	0.913	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.087	0.913	0.000
I60-I69 Cerebrovascular diseases	0.087	0.913	0.000
I23 Certain current complications following acute myocardial infarction	0.085	0.915	0.000
I21 Acute myocardial infarction	0.085	0.915	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.084	0.916	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.083	0.917	0.000
I10-I15 Hypertensive diseases	0.083	0.917	0.000
I65.2 Occlusion and stenosis of carotid artery	0.081	0.919	0.000
I21.9 Acute myocardial infarction, unspecified	0.079	0.921	0.000
I72.8 Aneurysm of other specified arteries	0.076	0.923	0.000
I63 Cerebral infarction	0.075	0.925	0.000
I77.1 Stricture of artery	0.074	0.926	0.000
I99 Other and unspecified disorders of circulatory system	0.074	0.926	0.000
I70.9 Generalised and unspecified atherosclerosis	0.072	0.928	0.000
I70.8 Atherosclerosis of other arteries	0.072	0.928	0.000
I70.1 Atherosclerosis of renal artery	0.072	0.928	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.072	0.928	0.000
I72.3 Aneurysm of iliac artery	0.071	0.928	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.070	0.929	0.000
I01.8 Other acute rheumatic heart disease	0.070	0.929	0.000
I01.2 Acute rheumatic myocarditis	0.070	0.929	0.000
I01.1 Acute rheumatic endocarditis	0.070	0.929	0.000
I01.0 Acute rheumatic pericarditis	0.070	0.929	0.000
I02.9 Rheumatic chorea without heart involvement	0.070	0.929	0.000
I02.0 Rheumatic chorea with heart involvement	0.070	0.929	0.000
I05-I09 Chronic rheumatic heart diseases	0.071	0.929	0.000
I15 Secondary hypertension	0.070	0.930	0.000
D64 Other anaemias	0.000	0.931	0.069
I22.0 Subsequent myocardial infarction of anterior wall	0.069	0.931	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.068	0.932	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.068	0.932	0.000
I73 Other peripheral vascular diseases	0.067	0.933	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.067	0.933	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.066	0.934	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.065	0.934	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.065	0.935	0.000
I70.0 Atherosclerosis of aorta	0.064	0.936	0.000
I22.8 Subsequent myocardial infarction of other sites	0.064	0.936	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.062	0.937	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.061	0.938	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.061	0.939	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.061	0.939	0.000
I23.8 Other current complications following acute myocardial infarction	0.061	0.939	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.061	0.939	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.061	0.939	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.061	0.939	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.061	0.939	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.061	0.939	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.061	0.939	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.061	0.939	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.061	0.939	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.061	0.939	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.061	0.939	0.000
I65.1 Occlusion and stenosis of basilar artery	0.061	0.939	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.061	0.939	0.000
I13 Hypertensive heart and renal disease	0.060	0.940	0.000
I15.1 Hypertension secondary to other renal disorders	0.060	0.940	0.000
I69 Sequelae of cerebrovascular disease	0.059	0.940	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.059	0.941	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.058	0.942	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.057	0.943	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.055	0.944	0.000
I69.3 Sequelae of cerebral infarction	0.055	0.945	0.000
I71 Aortic aneurysm and dissection	0.054	0.946	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.054	0.946	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.054	0.946	0.000
I15.9 Seconday hypertension, unspecified	0.053	0.946	0.000
I09 Other rheumatic heart diseases	0.053	0.947	0.000
I11 Hypertensive heart disease	0.053	0.947	0.000
I12 Hypertensive renal disease	0.052	0.947	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.052	0.948	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.052	0.948	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.052	0.948	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.052	0.948	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.052	0.948	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.052	0.948	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.052	0.948	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.052	0.948	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.052	0.948	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.052	0.948	0.000
I98.0 Cardiovascular syphilis	0.052	0.948	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.052	0.948	0.000
I06 Rheumatic aortic valve diseases	0.051	0.949	0.000
I15.8 Other secondary hypertension	0.050	0.949	0.000
I15.2 Hypertension secondary to endocrine disorders	0.050	0.949	0.000
I15.0 Renovascular hypertension	0.050	0.949	0.000
D64.8 Other specified anaemias	0.000	0.950	0.050
D64.4 Congenital dyserythropoietic anaemia	0.000	0.950	0.050
D64.3 Other sideroblastic anaemias	0.000	0.950	0.050
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.950	0.050
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.950	0.050
D64.0 Hereditary sideroblastic anaemia	0.000	0.950	0.050
I73.8 Other specified peripheral vascular diseases	0.048	0.952	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.048	0.952	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.048	0.952	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.048	0.952	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.048	0.952	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.048	0.952	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.048	0.952	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.048	0.952	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.047	0.953	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.046	0.954	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.045	0.955	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.045	0.955	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.045	0.955	0.000
I68.0 Cerebral amyloid angiopathy	0.045	0.955	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.044	0.956	0.000
I63.8 Other cerebral infarction	0.043	0.956	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.043	0.957	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.043	0.957	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.043	0.957	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.043	0.957	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.043	0.957	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.042	0.958	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.041	0.958	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.041	0.959	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.041	0.959	0.000
I97.0 Postcardiotomy syndrome	0.041	0.959	0.000
I62 Other nontraumatic intracranial haemorrhage	0.040	0.959	0.000
I09.9 Rheumatic heart disease, unspecified	0.040	0.960	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.040	0.960	0.000
I07 Rheumatic tricuspid valve diseases	0.039	0.960	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.039	0.960	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.039	0.961	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.039	0.961	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.039	0.961	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.039	0.961	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.039	0.961	0.000
I05 Rheumatic mitral valve diseases	0.038	0.961	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.038	0.961	0.000
I09.8 Other specified rheumatic heart diseases	0.038	0.962	0.000
I09.2 Chronic rheumatic pericarditis	0.038	0.962	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.038	0.962	0.000
I09.0 Rheumatic myocarditis	0.038	0.962	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.038	0.962	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.037	0.962	0.000
I61 Intracerebral haemorrhage	0.037	0.962	0.001
I12.9 Hypertensive renal disease without renal failure	0.037	0.963	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.036	0.963	0.000
I06.8 Other rheumatic aortic valve diseases	0.036	0.963	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.036	0.963	0.000
I06.1 Rheumatic aortic insufficiency	0.036	0.963	0.000
I06.0 Rheumatic aortic stenosis	0.036	0.963	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.036	0.964	0.000
I73.9 Peripheral vascular disease, unspecified	0.035	0.965	0.000
I60 Subarachnoid haemorrhage	0.034	0.966	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.034	0.966	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.033	0.966	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.033	0.967	0.000
I08 Multiple valve diseases	0.033	0.967	0.000
I71.0 Dissection of aorta [any part]	0.032	0.968	0.000
I20 Angina pectoris	0.032	0.968	0.000
I67 Other cerebrovascular diseases	0.032	0.968	0.000
I97.1 Other functional disturbances following cardiac surgery	0.031	0.969	0.000
I12.0 Hypertensive renal disease with renal failure	0.031	0.969	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.031	0.969	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.030	0.970	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.029	0.970	0.000
I62.1 Nontraumatic extradural haemorrhage	0.029	0.970	0.000
I07.9 Tricuspid valve disease, unspecified	0.028	0.971	0.000
I07.8 Other tricuspid valve diseases	0.028	0.971	0.000
I07.2 Tricuspid stenosis with insufficiency	0.028	0.971	0.000
I07.0 Tricuspid stenosis	0.028	0.971	0.000
I05.8 Other mitral valve diseases	0.028	0.972	0.000
I05.2 Mitral stenosis with insufficiency	0.028	0.972	0.000
I05.1 Rheumatic mitral insufficiency	0.028	0.972	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.027	0.972	0.000
I95 Hypotension	0.028	0.972	0.000
I61.8 Other intracerebral haemorrhage	0.027	0.973	0.001
I61.6 Intracerebral haemorrhage, multiple localised	0.027	0.973	0.001
I61.3 Intracerebral haemorrhage in brain stem	0.027	0.973	0.001
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.027	0.973	0.001
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.027	0.973	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.026	0.973	0.001
I67.9 Cerebrovascular disease, unspecified	0.027	0.973	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.025	0.974	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.025	0.975	0.000
I05.0 Mitral stenosis	0.024	0.975	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.024	0.975	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.024	0.975	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.024	0.975	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.024	0.975	0.000
I60.8 Other subarachnoid haemorrhage	0.024	0.976	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.024	0.976	0.000
I08.9 Multiple valve disease, unspecified	0.023	0.976	0.000
I20.0 Unstable angina	0.024	0.976	0.000
I08.8 Other multiple valve diseases	0.023	0.976	0.000
I95.2 Hypotension due to drugs	0.024	0.976	0.000
I20.1 Angina pectoris with documented spasm	0.023	0.977	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.023	0.977	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.023	0.977	0.000
I67.5 Moyamoya disease	0.023	0.977	0.000
I67.4 Hypertensive encephalopathy	0.023	0.977	0.000
I67.3 Progressive vascular leukoencephalopathy	0.023	0.977	0.000
I63.9 Cerebral infarction, unspecified	0.023	0.977	0.000
I73.0 Raynaud's syndrome	0.022	0.978	0.000
I05.9 Mitral valve disease, unspecified	0.021	0.979	0.001
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.021	0.979	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.020	0.979	0.000
I95.0 Idiopathic hypotension	0.020	0.980	0.000
I95.8 Other hypotension	0.018	0.981	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.018	0.982	0.000
I67.1 Cerebral aneurysm, nonruptured	0.018	0.982	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.018	0.982	0.001
I08.2 Disorders of both aortic and tricuspid valves	0.017	0.982	0.001
I07.1 Tricuspid insufficiency	0.017	0.982	0.001
Z87.1 Personal history of diseases of the digestive system	0.000	0.983	0.017
D60-D64 Aplastic and other anaemias	0.000	0.983	0.017
I21.4 Acute subendocardial myocardial infarction	0.016	0.983	0.000
I67.2 Cerebral atherosclerosis	0.016	0.984	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.015	0.984	0.001
I25.5 Ischaemic cardiomyopathy	0.016	0.984	0.000
I25 Chronic ischaemic heart disease	0.015	0.985	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.013	0.986	0.000
I67.8 Other specified cerebrovascular diseases	0.013	0.987	0.000
I20.8 Other forms of angina pectoris	0.013	0.987	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.988	0.012
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.988	0.012
I08.0 Disorders of both mitral and aortic valves	0.011	0.989	0.000
I25.6 Silent myocardial ischaemia	0.011	0.989	0.000
D62 Acute posthaemorrhagic anaemia	0.000	0.989	0.011
I25.4 Coronary artery aneurysm	0.011	0.989	0.000
K86.1 Other chronic pancreatitis	0.011	0.989	0.000
K86.3 Pseudocyst of pancreas	0.010	0.990	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.008	0.990	0.001
K86 Other diseases of pancreas	0.010	0.990	0.000
I25.3 Aneurysm of heart	0.009	0.991	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.009	0.991	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.000	0.991	0.009
D60.8 Other acquired pure red cell aplasias	0.000	0.991	0.009
D60.1 Transient acquired pure red cell aplasia	0.000	0.991	0.009
D60.0 Chronic acquired pure red cell aplasia	0.000	0.991	0.009
K86.8 Other specified diseases of pancreas	0.009	0.991	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.991	0.009
I08.1 Disorders of both mitral and tricuspid valves	0.008	0.991	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.991	0.008
D61 Other aplastic anaemias	0.000	0.991	0.008
Z92.1 Personal history of long-term (current) use of anticoagulants	0.008	0.992	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.007	0.992	0.001
D63.0 Anaemia in neoplastic disease	0.000	0.992	0.008
K86.9 Disease of pancreas, unspecified	0.008	0.992	0.000
H36.0 Diabetic retinopathy	0.007	0.993	0.000
K86.2 Cyst of pancreas	0.007	0.993	0.000
N85.8 Other specified noninflammatory disorders of uterus	0.007	0.993	0.000
D61.8 Other specified aplastic anaemias	0.000	0.994	0.006
D61.3 Idiopathic aplastic anaemia	0.000	0.994	0.006
D61.2 Aplastic anaemia due to other external agents	0.000	0.994	0.006
D61.0 Constitutional aplastic anaemia	0.000	0.994	0.006
Z42.1 Follow-up care involving plastic surgery of breast	0.000	0.994	0.006
N92 Excessive, frequent and irregular menstruation	0.000	0.994	0.006
I25.9 Chronic ischaemic heart disease, unspecified	0.006	0.994	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.006	0.994	0.000
I25.2 Old myocardial infarction	0.006	0.994	0.000
I95.1 Orthostatic hypotension	0.006	0.994	0.000
D61.1 Drug-induced aplastic anaemia	0.000	0.995	0.005
D47.2 Monoclonal gammopathy	0.005	0.995	0.000
N32.0 Bladder-neck obstruction	0.000	0.995	0.005
N02.9 Unspecified	0.005	0.995	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.995	0.005
D47.1 Chronic myeloproliferative disease	0.005	0.995	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.005	0.995	0.000
N92.2 Excessive menstruation at puberty	0.000	0.995	0.004
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.000	0.996	0.004
Z87 Personal history of other diseases and conditions	0.000	0.996	0.004
N81.2 Incomplete uterovaginal prolapse	0.004	0.996	0.000
O03.9 Complete or unspecified, without complication	0.000	0.996	0.004
O03.4 Incomplete, without complication	0.000	0.996	0.004
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.004	0.996	0.000
H36 Retinal disorders in diseases classified elsewhere	0.004	0.996	0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O14.9 Preeclampsia, unspecified	0.004	0.996	0.000
N81.1 Cystocele	0.004	0.996	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.996	0.004
O14.0 Moderate preeclampsia	0.004	0.996	0.000
N81.5 Vaginal enterocele	0.004	0.996	0.000
C50.5 Lower-outer quadrant of breast	0.000	0.996	0.004
C50.4 Upper-outer quadrant of breast	0.000	0.996	0.004
O14.1 Severe preeclampsia	0.003	0.996	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.003	0.996	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.003	0.996	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.003	0.996	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.003	0.996	0.000
Z87.8 Personal history of other specified conditions	0.000	0.996	0.004
O03 Spontaneous abortion	0.000	0.996	0.004
C50.9 Breast, unspecified	0.000	0.996	0.004
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.004	0.996	0.000
N81.0 Female urethrocele	0.003	0.996	0.000
D47.4 Osteomyelofibrosis	0.003	0.996	0.000
M75.0 Adhesive capsulitis of shoulder	0.000	0.996	0.004
N81 Female genital prolapse	0.004	0.996	0.000
R63.0 Anorexia	0.000	0.997	0.003
C50 Malignant neoplasm of breast	0.000	0.997	0.003
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.997	0.003
C50.2 Upper-inner quadrant of breast	0.000	0.997	0.003
D47.3 Essential (haemorrhagic) thrombocythaemia	0.003	0.997	0.000
D45 Polycythaemia vera	0.003	0.997	0.000
O16 Unspecified maternal hypertension	0.003	0.997	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
O14.2 HELLP syndrome	0.003	0.997	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.003	0.997	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.003	0.997	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.003	0.997	0.000
D48.1 Connective and other soft tissue	0.003	0.997	0.000
N92.4 Excessive bleeding in the premenopausal period	0.000	0.997	0.003
D48.7 Other specified sites	0.003	0.997	0.000
N81.3 Complete uterovaginal prolapse	0.003	0.997	0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.003	0.997	0.000
E11.3 With ophthalmic complications	0.003	0.997	0.000
Z87.6 Personal history of certain conditions arising in the perinatal period	0.000	0.997	0.003
C45.9 Mesothelioma, unspecified	0.003	0.997	0.000
N76.0 Acute vaginitis	0.003	0.997	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.003	0.997	0.000
N92.5 Other specified irregular menstruation	0.001	0.997	0.002
O03.8 Complete or unspecified, with other and unspecified complications	0.000	0.997	0.003
O03.7 Complete or unspecified, complicated by embolism	0.000	0.997	0.003
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.997	0.003
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.997	0.003
O03.3 Incomplete, with other and unspecified complications	0.000	0.997	0.003
O03.2 Incomplete, complicated by embolism	0.000	0.997	0.003
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.997	0.003
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.997	0.003
D46 Myelodysplastic syndromes	0.003	0.997	0.000
N76 Other inflammation of vagina and vulva	0.003	0.997	0.000
D48.6 Breast	0.003	0.997	0.000
N72 Inflammatory disease of cervix uteri	0.003	0.997	0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.003	0.997	0.000
C50.1 Central portion of breast	0.000	0.997	0.003
C50.6 Axillary tail of breast	0.000	0.997	0.003
O63.1 Prolonged second stage (of labour)	0.003	0.997	0.000
Y40.0 Penicillins	0.003	0.997	0.000
O15 Eclampsia	0.003	0.997	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.003	0.997	0.000
N02 Recurrent and persistent haematuria	0.003	0.997	0.000
C45.7 Mesothelioma of other sites	0.003	0.997	0.000
D43.2 Brain, unspecified	0.003	0.997	0.000
C45 Mesothelioma	0.003	0.997	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.003	0.997	0.000
N81.8 Other female genital prolapse	0.003	0.997	0.000
Z87.0 Personal history of diseases of the respiratory system	0.000	0.997	0.003
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.002	0.997	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.997	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.002	0.997	0.000
D48.4 Peritoneum	0.002	0.997	0.000
D48.3 Retroperitoneum	0.002	0.997	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.002	0.997	0.000
N81.9 Female genital prolapse, unspecified	0.002	0.997	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.002	0.997	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.997	0.000
I95.9 Hypotension, unspecified	0.002	0.997	0.000
L03.1 Cellulitis of other parts of limb	0.003	0.997	0.000
N76.2 Acute vulvitis	0.002	0.997	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.002	0.997	0.000
N76.3 Subacute and chronic vulvitis	0.002	0.998	0.000
W07.0 Home	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations