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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78606339
log Bayes Factor = 1.33923
Chromosome 5   position 165,428,979  (GRCh37) Explore rs78606339 on Ensembl!
Variant rs78606339 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
0.954 0.046 0.000
# Top node
0.949 0.051 0.000
I30-I52 Other forms of heart disease
0.949 0.051 0.000
Chapter VI Diseases of the nervous system
0.935 0.065 0.000
I45 Other conduction disorders
0.935 0.065 0.000
I60-I69 Cerebrovascular diseases
0.930 0.070 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.929 0.071 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.914 0.086 0.000
I45.1 Other and unspecified right bundle-branch block
0.904 0.096 0.000
Chapter VII Diseases of the eye and adnexa
0.903 0.097 0.000
M05-M14 Inflammatory polyarthropathies
0.893 0.107 0.000
I50 Heart failure
0.888 0.112 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.886 0.114 0.000
Chapter V Mental and behavioural disorders
0.882 0.118 0.000
I67 Other cerebrovascular diseases
0.870 0.130 0.000
M06 Other rheumatoid arthritis
0.869 0.131 0.000
F30-F39 Mood [affective] disorders
0.851 0.149 0.000
M06.9 Rheumatoid arthritis, unspecified
0.850 0.150 0.000
I63 Cerebral infarction
0.848 0.152 0.000
G90-G99 Other disorders of the nervous system
0.847 0.153 0.000
I20-I25 Ischaemic heart diseases
0.843 0.157 0.000
H30-H36 Disorders of choroid and retina
0.841 0.159 0.000
I47 Paroxysmal tachycardia
0.840 0.160 0.000
F32 Depressive episode
0.831 0.169 0.000
M45-M49 Spondylopathies
0.820 0.180 0.000
M20-M25 Other joint disorders
0.815 0.185 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.813 0.187 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.811 0.189 0.000
I45.5 Other specified heart block
0.810 0.190 0.000
I49 Other cardiac arrhythmias
0.807 0.193 0.000
I69 Sequelae of cerebrovascular disease
0.804 0.196 0.000
I05-I09 Chronic rheumatic heart diseases
0.802 0.198 0.000
Chapter XXII Codes for special purposes
0.800 0.200 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.799 0.201 0.000
F32.9 Depressive episode, unspecified
0.798 0.202 0.000
I50.0 Congestive heart failure
0.798 0.202 0.000
I51 Complications and ill-defined descriptions of heart disease
0.792 0.208 0.000
Chapter VIII Diseases of the ear and mastoid process
0.790 0.210 0.000
G20-G26 Extrapyramidal and movement disorders
0.788 0.212 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.784 0.216 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.783 0.217 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.781 0.219 0.000
I10-I15 Hypertensive diseases
0.772 0.228 0.000
M23 Internal derangement of knee
0.771 0.229 0.000
I63.9 Cerebral infarction, unspecified
0.769 0.231 0.000
H53-H54 Visual disturbances and blindness
0.768 0.232 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.765 0.235 0.000
I46 Cardiac arrest
0.765 0.235 0.000
H40-H42 Glaucoma
0.762 0.237 0.000
I21 Acute myocardial infarction
0.759 0.241 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.756 0.244 0.000
G30-G32 Other degenerative diseases of the nervous system
0.746 0.254 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.745 0.255 0.000
M50-M54 Other dorsopathies
0.744 0.256 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.742 0.258 0.000
I67.2 Cerebral atherosclerosis
0.739 0.261 0.000
I67.8 Other specified cerebrovascular diseases
0.738 0.262 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.738 0.262 0.000
H35 Other retinal disorders
0.737 0.263 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.736 0.264 0.000
I33 Acute and subacute endocarditis
0.736 0.264 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.730 0.270 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.729 0.271 0.000
T66-T78 Other and unspecified effects of external causes
0.729 0.271 0.000
I50.9 Heart failure, unspecified
0.727 0.273 0.000
I47.2 Ventricular tachycardia
0.727 0.273 0.000
I45.9 Conduction disorder, unspecified
0.725 0.275 0.000
I12 Hypertensive renal disease
0.724 0.276 0.000
H33 Retinal detachments and breaks
0.723 0.277 0.000
S70-S79 Injuries to the hip and thigh
0.722 0.278 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.722 0.278 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.719 0.281 0.000
M47 Spondylosis
0.717 0.283 0.000
G81 Hemiplegia
0.716 0.284 0.000
H10-H13 Disorders of conjunctiva
0.716 0.284 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.711 0.289 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.707 0.293 0.000
M91-M94 Chondropathies
0.705 0.295 0.000
M07 Psoriatic and enteropathic arthropathies
0.704 0.296 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.704 0.296 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.703 0.297 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.702 0.298 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.701 0.299 0.000
I45.6 Preexcitation syndrome
0.700 0.300 0.000
M86-M90 Other osteopathies
0.699 0.300 0.000
I50.1 Left ventricular failure
0.699 0.301 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.698 0.302 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.697 0.303 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.696 0.304 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.696 0.304 0.000
I67.9 Cerebrovascular disease, unspecified
0.690 0.310 0.000
M40-M43 Deforming dorsopathies
0.689 0.311 0.000
G95 Other diseases of spinal cord
0.689 0.311 0.000
I51.7 Cardiomegaly
0.688 0.312 0.000
I12.0 Hypertensive renal disease with renal failure
0.686 0.314 0.000
I63.8 Other cerebral infarction
0.684 0.316 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.684 0.316 0.000
I00-I02 Acute rheumatic fever
0.684 0.316 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.683 0.317 0.000
I20 Angina pectoris
0.683 0.317 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.680 0.319 0.000
I52 Other heart disorders in diseases classified elsewhere
0.680 0.320 0.000
I48 Atrial fibrillation and flutter
0.680 0.320 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.680 0.320 0.000
I41 Myocarditis in diseases classified elsewhere
0.680 0.320 0.000
I40 Acute myocarditis
0.680 0.320 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.680 0.320 0.000
I37 Pulmonary valve disorders
0.680 0.320 0.000
I36 Nonrheumatic tricuspid valve disorders
0.680 0.320 0.000
I32 Pericarditis in diseases classified elsewhere
0.680 0.320 0.000
I30 Acute pericarditis
0.680 0.320 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.678 0.322 0.000
I21.9 Acute myocardial infarction, unspecified
0.677 0.323 0.000
H55-H59 Other disorders of eye and adnexa
0.677 0.323 0.000
S90-S99 Injuries to the ankle and foot
0.676 0.324 0.000
I47.1 Supraventricular tachycardia
0.676 0.324 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.675 0.325 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.674 0.326 0.000
G70-G73 Diseases of myoneural junction and muscle
0.670 0.330 0.000
I45.8 Other specified conduction disorders
0.670 0.330 0.000
I45.4 Nonspecific intraventricular block
0.670 0.330 0.000
I45.3 Trifascicular block
0.670 0.330 0.000
I45.2 Bifascicular block
0.670 0.330 0.000
I45.0 Right fascicular block
0.670 0.330 0.000
M10 Gout
0.669 0.331 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.667 0.333 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.666 0.333 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.666 0.333 0.000
M60-M63 Disorders of muscles
0.666 0.334 0.000
M00-M03 Infectious arthropathies
0.666 0.334 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.666 0.334 0.000
H35.3 Degeneration of macula and posterior pole
0.666 0.334 0.000
H90-H95 Other disorders of ear
0.663 0.337 0.000
I67.1 Cerebral aneurysm, nonruptured
0.663 0.337 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.662 0.338 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.662 0.338 0.000
H40 Glaucoma
0.662 0.338 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.661 0.339 0.000
I49.5 Sick sinus syndrome
0.660 0.340 0.000
I49.9 Cardiac arrhythmia, unspecified
0.658 0.342 0.000
I69.3 Sequelae of cerebral infarction
0.656 0.344 0.000
T79-T79 Certain early complications of trauma
0.655 0.345 0.000
T33-T35 Frostbite
0.655 0.345 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.655 0.345 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.655 0.345 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.655 0.345 0.000
T00-T07 Injuries involving multiple body regions
0.655 0.345 0.000
S10-S19 Injuries to the neck
0.655 0.345 0.000
H33.2 Serous retinal detachment
0.655 0.345 0.000
L20-L30 Dermatitis and eczema
0.654 0.346 0.000
M51 Other intervertebral disk disorders
0.654 0.346 0.000
M06.0 Seronegative rheumatoid arthritis
0.653 0.347 0.000
H60-H62 Diseases of external ear
0.653 0.347 0.000
I62 Other nontraumatic intracranial haemorrhage
0.653 0.347 0.000
G93 Other disorders of brain
0.653 0.347 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.649 0.351 0.000
I05 Rheumatic mitral valve diseases
0.648 0.351 0.000
G81.9 Hemiplegia, unspecified
0.648 0.352 0.000
I65.2 Occlusion and stenosis of carotid artery
0.648 0.352 0.000
M65-M68 Disorders of synovium and tendon
0.648 0.352 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.647 0.353 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.647 0.353 0.000
F33 Recurrent depressive disorder
0.646 0.354 0.000
I22 Subsequent myocardial infarction
0.646 0.354 0.000
M48 Other spondylopathies
0.645 0.354 0.000
I08 Multiple valve diseases
0.645 0.355 0.000
H34 Retinal vascular occlusions
0.643 0.357 0.000
M14 Arthropathies in other diseases classified elsewhere
0.640 0.360 0.000
M12 Other specific arthropathies
0.640 0.360 0.000
M11 Other crystal arthropathies
0.640 0.360 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.640 0.360 0.000
M08 Juvenile arthritis
0.640 0.360 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.640 0.360 0.000
S80-S89 Injuries to the knee and lower leg
0.638 0.362 0.000
G61 Inflammatory polyneuropathy
0.638 0.362 0.000
I49.8 Other specified cardiac arrhythmias
0.637 0.363 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.637 0.363 0.000
F32.1 Moderate depressive episode
0.637 0.363 0.000
M34 Systemic sclerosis
0.637 0.363 0.000
T39.1 4-Aminophenol derivatives
0.637 0.363 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.635 0.364 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.635 0.364 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.635 0.364 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.635 0.364 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.635 0.364 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.635 0.364 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.635 0.364 0.000
T36 Poisoning by systemic antibiotics
0.635 0.364 0.000
F99-F99 Unspecified mental disorder
0.632 0.367 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.632 0.367 0.000
F80-F89 Disorders of psychological development
0.632 0.367 0.000
F70-F79 Mental retardation
0.632 0.367 0.000
F60-F69 Disorders of adult personality and behaviour
0.632 0.367 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.632 0.367 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.632 0.368 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.631 0.369 0.000
H54 Blindness and low vision
0.630 0.369 0.000
G20 Parkinson's disease
0.630 0.370 0.000
M05 Seropositive rheumatoid arthritis
0.629 0.371 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.627 0.373 0.000
S00-S09 Injuries to the head
0.626 0.373 0.000
G96 Other disorders of central nervous system
0.626 0.374 0.000
G40-G47 Episodic and paroxysmal disorders
0.626 0.374 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.626 0.374 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.626 0.374 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.623 0.376 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.623 0.376 0.000
I67.5 Moyamoya disease
0.623 0.376 0.000
I67.4 Hypertensive encephalopathy
0.623 0.376 0.000
I67.3 Progressive vascular leukoencephalopathy
0.623 0.376 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.623 0.376 0.000
M06.8 Other specified rheumatoid arthritis
0.623 0.377 0.000
M06.4 Inflammatory polyarthropathy
0.623 0.377 0.000
M06.3 Rheumatoid nodule
0.623 0.377 0.000
M06.2 Rheumatoid bursitis
0.623 0.377 0.000
M06.1 Adult-onset Still's disease
0.623 0.377 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.623 0.377 0.000
G25 Other extrapyramidal and movement disorders
0.622 0.378 0.000
M31 Other necrotising vasculopathies
0.620 0.380 0.000
I51.9 Heart disease, unspecified
0.617 0.383 0.000
H53 Visual disturbances
0.616 0.384 0.000
M35 Other systemic involvement of connective tissue
0.616 0.384 0.000
M47.9 Spondylosis, unspecified
0.613 0.386 0.000
Q50-Q56 Congenital malformations of genital organs
0.612 0.388 0.000
I46.9 Cardiac arrest, unspecified
0.611 0.388 0.000
M24 Other specific joint derangements
0.611 0.389 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.611 0.389 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.611 0.389 0.000
L40-L45 Papulosquamous disorders
0.610 0.390 0.000
F38 Other mood [affective] disorders
0.610 0.390 0.000
F34 Persistent mood [affective] disorders
0.610 0.390 0.000
F30 Manic episode
0.610 0.390 0.000
F39 Unspecified mood [affective] disorder
0.610 0.390 0.000
M22 Disorders of patella
0.610 0.390 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.610 0.390 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.610 0.390 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.610 0.390 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.610 0.390 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.610 0.390 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.610 0.390 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.610 0.390 0.000
L84 Corns and callosities
0.610 0.390 0.000
Chapter I Certain infectious and parasitic diseases
0.609 0.391 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.608 0.392 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.608 0.392 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.608 0.392 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.608 0.392 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.608 0.392 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.608 0.392 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.607 0.393 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.607 0.393 0.000
G91 Hydrocephalus
0.607 0.393 0.000
G90 Disorders of autonomic nervous system
0.607 0.393 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.607 0.393 0.000
G92 Toxic encephalopathy
0.607 0.393 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.607 0.393 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.606 0.394 0.000
L91 Hypertrophic disorders of skin
0.606 0.394 0.000
I23 Certain current complications following acute myocardial infarction
0.605 0.395 0.000
T68 Hypothermia
0.603 0.397 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.603 0.397 0.000
H31 Other disorders of choroid
0.603 0.397 0.000
H30 Chorioretinal inflammation
0.603 0.397 0.000
H43-H45 Disorders of vitreous body and globe
0.602 0.397 0.000
I34 Nonrheumatic mitral valve disorders
0.602 0.398 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.602 0.398 0.000
I47.0 Reentry ventricular arrhythmia
0.602 0.398 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.602 0.398 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.600 0.400 0.000
I35 Nonrheumatic aortic valve disorders
0.600 0.400 0.000
I24 Other acute ischaemic heart diseases
0.600 0.400 0.000
T39.0 Salicylates
0.598 0.402 0.000
I38 Endocarditis, valve unspecified
0.598 0.402 0.000
G82 Paraplegia and tetraplegia
0.597 0.403 0.000
T31 Burns classified according to extent of body surface involved
0.597 0.403 0.000
F32.8 Other depressive episodes
0.596 0.404 0.000
F32.0 Mild depressive episode
0.596 0.404 0.000
S20-S29 Injuries to the thorax
0.596 0.404 0.000
G35 Multiple sclerosis
0.594 0.406 0.000
I60 Subarachnoid haemorrhage
0.592 0.408 0.000
S50-S59 Injuries to the elbow and forearm
0.591 0.409 0.000
M51.2 Other specified intervertebral disk displacement
0.591 0.409 0.000
I20.0 Unstable angina
0.591 0.409 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.590 0.410 0.000
G24 Dystonia
0.590 0.410 0.000
H36 Retinal disorders in diseases classified elsewhere
0.590 0.410 0.000
M46 Other inflammatory spondylopathies
0.589 0.411 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.588 0.412 0.000
M49 Spondylopathies in diseases classified elsewhere
0.588 0.412 0.000
M80-M85 Disorders of bone density and structure
0.588 0.412 0.000
H35.0 Background retinopathy and retinal vascular changes
0.586 0.414 0.000
L50-L54 Urticaria and erythema
0.585 0.415 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.584 0.416 0.000
M33 Dermatopolymyositis
0.584 0.416 0.000
M32 Systemic lupus erythematosus
0.584 0.416 0.000
M30 Polyarteritis nodosa and related conditions
0.584 0.416 0.000
M21 Other acquired deformities of limbs
0.584 0.416 0.000
I33.0 Acute and subacute infective endocarditis
0.583 0.417 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.582 0.418 0.000
M45 Ankylosing spondylitis
0.582 0.418 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.581 0.418 0.000
G83 Other paralytic syndromes
0.582 0.418 0.000
G80 Infantile cerebral palsy
0.582 0.418 0.000
I46.0 Cardiac arrest with successful resuscitation
0.581 0.419 0.000
I49.4 Other and unspecified premature depolarisation
0.579 0.421 0.000
I49.2 Junctional premature depolarisation
0.579 0.421 0.000
I49.1 Atrial premature depolarisation
0.579 0.421 0.000
I49.0 Ventricular fibrillation and flutter
0.579 0.421 0.000
M23.4 Loose body in knee
0.578 0.422 0.000
G62 Other polyneuropathies
0.578 0.422 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.577 0.423 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.576 0.423 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.576 0.423 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.576 0.423 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.576 0.423 0.000
I09 Other rheumatic heart diseases
0.575 0.425 0.000
I06 Rheumatic aortic valve diseases
0.575 0.425 0.000
F20 Schizophrenia
0.575 0.425 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.574 0.426 0.000
I61 Intracerebral haemorrhage
0.574 0.426 0.000
M47.8 Other spondylosis
0.574 0.426 0.000
S71 Open wound of hip and thigh
0.573 0.427 0.000
U80 Agent resistant to penicillin and related antibiotics
0.573 0.427 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.573 0.427 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.573 0.427 0.000
T39.4 Antirheumatics, not elsewhere classified
0.573 0.427 0.000
T39.2 Pyrazolone derivatives
0.573 0.427 0.000
H90 Conductive and sensorineural hearing loss
0.572 0.428 0.000
T43.2 Other and unspecified antidepressants
0.571 0.429 0.000
M07.3 Other psoriatic arthropathies
0.568 0.432 0.000
I07 Rheumatic tricuspid valve diseases
0.568 0.432 0.000
I51.6 Cardiovascular disease, unspecified
0.568 0.432 0.000
I51.5 Myocardial degeneration
0.568 0.432 0.000
I51.4 Myocarditis, unspecified
0.568 0.432 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.568 0.432 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.568 0.432 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.568 0.432 0.000
I51.0 Cardiac septal defect, acquired
0.568 0.432 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.566 0.434 0.000
G23 Other degenerative diseases of basal ganglia
0.565 0.435 0.000
G21 Secondary Parkinsonism
0.565 0.435 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.565 0.435 0.000
G22 Parkinsonism in diseases classified elsewhere
0.565 0.435 0.000
L10-L14 Bullous disorders
0.562 0.438 0.000
H33.0 Retinal detachment with retinal break
0.562 0.438 0.000
G60 Hereditary and idiopathic neuropathy
0.561 0.439 0.000
G64 Other disorders of peripheral nervous system
0.561 0.439 0.000
T45.0 Antiallergic and antiemetic drugs
0.560 0.440 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.560 0.440 0.000
Q80-Q89 Other congenital malformations
0.560 0.440 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.560 0.440 0.000
Q60-Q64 Congenital malformations of the urinary system
0.560 0.440 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.560 0.440 0.000
Q35-Q37 Cleft lip and cleft palate
0.560 0.440 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.560 0.440 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.560 0.440 0.000
Q00-Q07 Congenital malformations of the nervous system
0.560 0.440 0.000
H10 Conjunctivitis
0.560 0.440 0.000
I20.8 Other forms of angina pectoris
0.560 0.440 0.000
I99 Other and unspecified disorders of circulatory system
0.559 0.441 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.558 0.441 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.555 0.445 0.000
H25-H28 Disorders of lens
0.554 0.446 0.000
G95.9 Disease of spinal cord, unspecified
0.554 0.446 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.553 0.447 0.000
I15 Secondary hypertension
0.553 0.447 0.000
I13 Hypertensive heart and renal disease
0.553 0.447 0.000
I11 Hypertensive heart disease
0.553 0.447 0.000
M23.9 Internal derangement of knee, unspecified
0.553 0.447 0.000
M23.5 Chronic instability of knee
0.553 0.447 0.000
M23.1 Discoid meniscus (congenital)
0.553 0.447 0.000
M23.0 Cystic meniscus
0.553 0.447 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.552 0.448 0.000
L27 Dermatitis due to substances taken internally
0.552 0.448 0.000
L82 Seborrhoeic keratosis
0.550 0.450 0.000
H40.9 Glaucoma, unspecified
0.549 0.451 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.549 0.451 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.549 0.451 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.549 0.451 0.000
I65.1 Occlusion and stenosis of basilar artery
0.549 0.451 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.549 0.451 0.000
I46.1 Sudden cardiac death, so described
0.549 0.451 0.000
H42 Glaucoma in diseases classified elsewhere
0.547 0.453 0.000
H61 Other disorders of external ear
0.546 0.453 0.000
T90 Sequelae of injuries of head
0.546 0.454 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.544 0.456 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.544 0.456 0.000
M93 Other osteochondropathies
0.544 0.456 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.543 0.457 0.000
T50.8 Diagnostic agents
0.542 0.458 0.000
T50.7 Analeptics and opioid receptor antagonists
0.542 0.458 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.542 0.458 0.000
T50.5 Appetite depressants
0.542 0.458 0.000
T50.4 Drugs affecting uric acid metabolism
0.542 0.458 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.542 0.458 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.542 0.458 0.000
T50.1 Loop [high-ceiling] diuretics
0.542 0.458 0.000
T50.0 Mineralocorticoids and their antagonists
0.542 0.458 0.000
G95.8 Other specified diseases of spinal cord
0.542 0.458 0.000
H11 Other disorders of conjunctiva
0.541 0.459 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.541 0.459 0.000
I12.9 Hypertensive renal disease without renal failure
0.541 0.459 0.000
U51 Admission status on psychiatric patients
0.540 0.460 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.539 0.460 0.000
I05.9 Mitral valve disease, unspecified
0.539 0.461 0.000
M87 Osteonecrosis
0.538 0.462 0.000
L89 Decubitus ulcer
0.538 0.462 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.537 0.462 0.000
M23.8 Other internal derangements of knee
0.537 0.463 0.000
S40-S49 Injuries to the shoulder and upper arm
0.536 0.463 0.000
L90 Atrophic disorders of skin
0.536 0.464 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.535 0.465 0.000
T93 Sequelae of injuries of lower limb
0.534 0.466 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.534 0.466 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.534 0.466 0.000
G61.0 Guillain-Barre syndrome
0.534 0.466 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.534 0.466 0.000
M53 Other dorsopathies, not elsewhere classified
0.533 0.466 0.000
S70 Superficial injury of hip and thigh
0.532 0.468 0.000
H40.5 Glaucoma secondary to other eye disorders
0.532 0.468 0.000
T87 Complications peculiar to reattachment and amputation
0.529 0.471 0.000
T86 Failure and rejection of transplanted organs and tissues
0.529 0.471 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.529 0.471 0.000
H35.9 Retinal disorder, unspecified
0.529 0.471 0.000
H35.7 Separation of retinal layers
0.529 0.471 0.000
H35.6 Retinal haemorrhage
0.529 0.471 0.000
H35.5 Hereditary retinal dystrophy
0.529 0.471 0.000
H35.4 Peripheral retinal degeneration
0.529 0.471 0.000
H35.2 Other proliferative retinopathy
0.529 0.471 0.000
H35.1 Retinopathy of prematurity
0.529 0.471 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.528 0.471 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.528 0.472 0.000
G37 Other demyelinating diseases of central nervous system
0.528 0.472 0.000
G36 Other acute disseminated demyelination
0.528 0.472 0.000
I33.9 Acute endocarditis, unspecified
0.527 0.472 0.000
F31 Bipolar affective disorder
0.526 0.473 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.525 0.475 0.000
H65-H75 Diseases of middle ear and mastoid
0.524 0.476 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.523 0.477 0.000
H46 Optic neuritis
0.523 0.477 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.523 0.477 0.000
B35-B49 Mycoses
0.523 0.477 0.000
T32 Corrosions classified according to extent of body surface involved
0.523 0.477 0.000
T30 Burn and corrosion, body region unspecified
0.523 0.477 0.000
T29 Burns and corrosions of multiple body regions
0.523 0.477 0.000
T75 Effects of other external causes
0.523 0.477 0.000
T74 Maltreatment syndromes
0.523 0.477 0.000
T73 Effects of other deprivation
0.523 0.477 0.000
T70 Effects of air pressure and water pressure
0.523 0.477 0.000
T69 Other effects of reduced temperature
0.523 0.477 0.000
T67 Effects of heat and light
0.523 0.477 0.000
T71 Asphyxiation
0.523 0.477 0.000
T66 Unspecified effects of radiation
0.523 0.477 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.522 0.478 0.000
H40.0 Glaucoma suspect
0.522 0.478 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.521 0.479 0.000
M48.0 Spinal stenosis
0.521 0.479 0.000
S72 Fracture of femur
0.520 0.479 0.000
L91.8 Other hypertrophic disorders of skin
0.520 0.480 0.000
S60-S69 Injuries to the wrist and hand
0.519 0.480 0.000
H53.1 Subjective visual disturbances
0.519 0.481 0.000
M70-M79 Other soft tissue disorders
0.519 0.481 0.000
H33.5 Other retinal detachments
0.519 0.481 0.000
H33.4 Traction detachment of retina
0.519 0.481 0.000
H33.1 Retinoschisis and retinal cysts
0.519 0.481 0.000
G40 Epilepsy
0.519 0.481 0.000
S79 Other and unspecified injuries of hip and thigh
0.518 0.482 0.000
S78 Traumatic amputation of hip and thigh
0.518 0.482 0.000
S77 Crushing injury of hip and thigh
0.518 0.482 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.518 0.482 0.000
S75 Injury of blood vessels at hip and thigh level
0.518 0.482 0.000
S74 Injury of nerves at hip and thigh level
0.518 0.482 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.518 0.482 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.517 0.483 0.000
H47.3 Other disorders of optic disk
0.517 0.483 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.516 0.484 0.000
G93.8 Other specified disorders of brain
0.516 0.484 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.515 0.485 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.515 0.485 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.515 0.485 0.000
H55 Nystagmus and other irregular eye movements
0.515 0.485 0.000
I08.0 Disorders of both mitral and aortic valves
0.515 0.485 0.000
M47.2 Other spondylosis with radiculopathy
0.514 0.486 0.000
M47.1 Other spondylosis with myelopathy
0.514 0.486 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.514 0.486 0.000
G81.1 Spastic hemiplegia
0.513 0.486 0.000
G81.0 Flaccid hemiplegia
0.513 0.486 0.000
H80-H83 Diseases of inner ear
0.513 0.487 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.513 0.487 0.000
H54.9 Unspecified visual impairment (binocular)
0.513 0.487 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.512 0.487 0.000
T78 Adverse effects, not elsewhere classified
0.511 0.489 0.000
M43 Other deforming dorsopathies
0.511 0.489 0.000
T92 Sequelae of injuries of upper limb
0.510 0.490 0.000
T40.2 Other opioids
0.510 0.490 0.000
T98 Sequelae of other and unspecified effects of external causes
0.510 0.490 0.000
T95 Sequelae of burns, corrosions and frostbite
0.510 0.490 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.510 0.490 0.000
T91 Sequelae of injuries of neck and trunk
0.510 0.490 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.510 0.490 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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