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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78690056
log Bayes Factor = 12.2007
Chromosome 4   position 126,086,818  (GRCh37) Explore rs78690056 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.998 0.002 0.000
S00-S09 Injuries to the head
0.996 0.004 0.000
I60-I69 Cerebrovascular diseases
0.996 0.004 0.000
R26 Abnormalities of gait and mobility
0.990 0.010 0.000
S01 Open wound of head
0.989 0.011 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.986 0.014 0.000
Chapter XX External causes of morbidity and mortality
0.985 0.015 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.984 0.016 0.000
I44 Atrioventricular and left bundle-branch block
0.982 0.018 0.000
S01.8 Open wound of other parts of head
0.980 0.020 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.975 0.025 0.000
E65-E68 Obesity and other hyperalimentation
0.962 0.038 0.000
Chapter I Certain infectious and parasitic diseases
0.958 0.042 0.000
R42 Dizziness and giddiness
0.948 0.052 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.946 0.054 0.000
E66 Obesity
0.945 0.055 0.000
E50-E64 Other nutritional deficiencies
0.939 0.061 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.937 0.063 0.000
B25-B34 Other viral diseases
0.937 0.063 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.931 0.069 0.000
R47-R49 Symptoms and signs involving speech and voice
0.930 0.070 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.925 0.075 0.000
E66.9 Obesity, unspecified
0.924 0.076 0.000
I33 Acute and subacute endocarditis
0.922 0.078 0.000
B34 Viral infection of unspecified site
0.922 0.078 0.000
I20-I25 Ischaemic heart diseases
0.921 0.079 0.000
I47 Paroxysmal tachycardia
0.918 0.082 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.916 0.084 0.000
I65.2 Occlusion and stenosis of carotid artery
0.911 0.089 0.000
B34.9 Viral infection, unspecified
0.911 0.089 0.000
I67 Other cerebrovascular diseases
0.907 0.093 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.905 0.095 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.902 0.098 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.902 0.098 0.000
I44.7 Left bundle-branch block, unspecified
0.899 0.101 0.000
E55 Vitamin D deficiency
0.887 0.113 0.000
Chapter XI Diseases of the digestive system
0.883 0.117 0.000
Y95 Nosocomial condition
0.883 0.117 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.882 0.118 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.881 0.119 0.000
I51 Complications and ill-defined descriptions of heart disease
0.881 0.119 0.000
R47 Speech disturbances, not elsewhere classified
0.877 0.123 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.877 0.123 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.876 0.124 0.000
S01.0 Open wound of scalp
0.876 0.124 0.000
R30-R39 Symptoms and signs involving the urinary system
0.875 0.125 0.000
Chapter VII Diseases of the eye and adnexa
0.872 0.128 0.000
I33.0 Acute and subacute infective endocarditis
0.867 0.133 0.000
E20-E35 Disorders of other endocrine glands
0.866 0.134 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.863 0.137 0.000
S00 Superficial injury of head
0.855 0.145 0.000
Chapter VIII Diseases of the ear and mastoid process
0.852 0.148 0.000
E55.9 Vitamin D deficiency, unspecified
0.850 0.150 0.000
I21 Acute myocardial infarction
0.848 0.152 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.848 0.152 0.000
I45 Other conduction disorders
0.844 0.156 0.000
I38 Endocarditis, valve unspecified
0.842 0.158 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.842 0.158 0.000
R35 Polyuria
0.837 0.163 0.000
Chapter XXI Factors influencing health status and contact with health services
0.831 0.169 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.831 0.169 0.000
R27 Other lack of coordination
0.829 0.170 0.000
S01.2 Open wound of nose
0.829 0.171 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.825 0.175 0.000
S06 Intracranial injury
0.824 0.176 0.000
R20 Disturbances of skin sensation
0.822 0.178 0.000
I44.2 Atrioventricular block, complete
0.821 0.179 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.821 0.179 0.000
Chapter V Mental and behavioural disorders
0.819 0.181 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.818 0.182 0.000
Chapter XXII Codes for special purposes
0.817 0.183 0.000
R45 Symptoms and signs involving emotional state
0.815 0.185 0.000
I44.6 Other and unspecified fascicular block
0.813 0.187 0.000
R26.0 Ataxic gait
0.812 0.188 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.812 0.188 0.000
I46 Cardiac arrest
0.811 0.189 0.000
O60-O75 Complications of labour and delivery
0.810 0.190 0.000
I47.1 Supraventricular tachycardia
0.810 0.190 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.810 0.190 0.000
S50-S59 Injuries to the elbow and forearm
0.808 0.191 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.805 0.195 0.000
I67.9 Cerebrovascular disease, unspecified
0.805 0.195 0.000
I44.1 Atrioventricular block, second degree
0.804 0.196 0.000
R47.0 Dysphasia and aphasia
0.803 0.197 0.000
I69 Sequelae of cerebrovascular disease
0.802 0.198 0.000
T79-T79 Certain early complications of trauma
0.801 0.199 0.000
K70-K77 Diseases of liver
0.801 0.199 0.000
R39 Other symptoms and signs involving the urinary system
0.798 0.202 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.797 0.203 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.795 0.205 0.000
K65-K67 Diseases of peritoneum
0.792 0.208 0.000
E66.8 Other obesity
0.792 0.208 0.000
Y40 Systemic antibiotics
0.791 0.209 0.000
I47.2 Ventricular tachycardia
0.790 0.210 0.000
H53-H54 Visual disturbances and blindness
0.790 0.210 0.000
I71 Aortic aneurysm and dissection
0.789 0.210 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.789 0.211 0.000
T92 Sequelae of injuries of upper limb
0.788 0.212 0.000
K13 Other diseases of lip and oral mucosa
0.784 0.216 0.000
R26.3 Immobility
0.782 0.218 0.000
T66-T78 Other and unspecified effects of external causes
0.782 0.218 0.000
I21.9 Acute myocardial infarction, unspecified
0.780 0.220 0.000
I51.0 Cardiac septal defect, acquired
0.780 0.220 0.000
I67.8 Other specified cerebrovascular diseases
0.779 0.221 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.778 0.221 0.000
T91 Sequelae of injuries of neck and trunk
0.778 0.222 0.000
R39.1 Other difficulties with micturition
0.777 0.223 0.000
S10-S19 Injuries to the neck
0.776 0.224 0.000
R43 Disturbances of smell and taste
0.775 0.225 0.000
I61 Intracerebral haemorrhage
0.773 0.227 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.773 0.227 0.000
I36 Nonrheumatic tricuspid valve disorders
0.773 0.227 0.000
R21 Rash and other nonspecific skin eruption
0.773 0.227 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.773 0.227 0.000
S01.4 Open wound of cheek and temporomandibular area
0.771 0.229 0.000
S00.0 Superficial injury of scalp
0.769 0.231 0.000
I44.0 Atrioventricular block, first degree
0.768 0.231 0.000
E40-E46 Malnutrition
0.766 0.234 0.000
X60-X84 Intentional self-harm
0.765 0.235 0.000
R47.8 Other and unspecified speech disturbances
0.765 0.235 0.000
S90-S99 Injuries to the ankle and foot
0.765 0.235 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.763 0.237 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.763 0.237 0.000
I22 Subsequent myocardial infarction
0.760 0.240 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.759 0.241 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.756 0.244 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.755 0.245 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.754 0.246 0.000
W00-W19 Falls
0.754 0.246 0.000
K90-K93 Other diseases of the digestive system
0.753 0.246 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.751 0.249 0.000
I44.3 Other and unspecified atrioventricular block
0.750 0.250 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.750 0.250 0.000
O85-O92 Complications predominantly related to the puerperium
0.749 0.251 0.000
R23 Other skin changes
0.749 0.251 0.000
S01.7 Multiple open wounds of head
0.748 0.252 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.748 0.252 0.000
H90-H95 Other disorders of ear
0.745 0.255 0.000
I24 Other acute ischaemic heart diseases
0.744 0.256 0.000
S20-S29 Injuries to the thorax
0.742 0.258 0.000
E61 Deficiency of other nutrient elements
0.742 0.258 0.000
W20-W49 Exposure to inanimate mechanical forces
0.742 0.258 0.000
I60 Subarachnoid haemorrhage
0.740 0.260 0.000
B95-B98 Bacterial, viral and other infectious agents
0.740 0.260 0.000
I27 Other pulmonary heart diseases
0.739 0.261 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.739 0.261 0.000
Y85 Sequelae of transport accidents
0.737 0.263 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.733 0.267 0.000
I62 Other nontraumatic intracranial haemorrhage
0.731 0.268 0.000
R29.6 Tendency to fall, not elsewhere classified
0.731 0.269 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.730 0.270 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.727 0.273 0.000
K76 Other diseases of liver
0.726 0.274 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.725 0.275 0.000
I45.9 Conduction disorder, unspecified
0.725 0.275 0.000
S09 Other and unspecified injuries of head
0.723 0.277 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.723 0.277 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.722 0.278 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.721 0.279 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.719 0.281 0.000
H54 Blindness and low vision
0.718 0.282 0.000
I72 Other aneurysm
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
S08 Traumatic amputation of part of head
0.714 0.286 0.000
S07 Crushing injury of head
0.714 0.286 0.000
S05 Injury of eye and orbit
0.714 0.286 0.000
S04 Injury of cranial nerves
0.714 0.286 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.714 0.286 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.714 0.286 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.714 0.286 0.000
S01.3 Open wound of ear
0.711 0.289 0.000
I63 Cerebral infarction
0.710 0.290 0.000
R26.1 Paralytic gait
0.710 0.290 0.000
L20-L30 Dermatitis and eczema
0.709 0.291 0.000
H04 Disorders of lachrymal system
0.708 0.292 0.000
I30 Acute pericarditis
0.708 0.292 0.000
R27.0 Ataxia, unspecified
0.708 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.706 0.294 0.000
Y35-Y36 Legal intervention and operations of war
0.706 0.294 0.000
Y10-Y34 Event of undetermined intent
0.706 0.294 0.000
Y00-Y09 Assault
0.706 0.294 0.000
X85-X99 Assault
0.706 0.294 0.000
X50-X57 Overexertion, travel and privation
0.706 0.294 0.000
X30-X39 Exposure to forces of nature
0.706 0.294 0.000
X20-X29 Contact with venomous animals and plants
0.706 0.294 0.000
X10-X19 Contact with heat and hot substances
0.706 0.294 0.000
X00-X09 Exposure to smoke, fire and flames
0.706 0.294 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.706 0.294 0.000
W75-W84 Other accidental threats to breathing
0.706 0.294 0.000
W65-W74 Accidental drowning and submersion
0.706 0.294 0.000
W50-W64 Exposure to animate mechanical forces
0.706 0.294 0.000
V98-V99 Other and unspecified transport accidents
0.706 0.294 0.000
V95-V97 Air and space transport accidents
0.706 0.294 0.000
V90-V94 Water transport accidents
0.706 0.294 0.000
V70-V79 Bus occupant injured in transport accident
0.706 0.294 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.706 0.294 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.706 0.294 0.000
V40-V49 Car occupant injured in transport accident
0.706 0.294 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.706 0.294 0.000
V01-V09 Pedestrian injured in transport accident
0.706 0.294 0.000
I21.4 Acute subendocardial myocardial infarction
0.706 0.294 0.000
R46 Symptoms and signs involving appearance and behaviour
0.705 0.294 0.000
K14 Diseases of tongue
0.705 0.295 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.705 0.295 0.000
I44.5 Left posterior fascicular block
0.704 0.296 0.000
I44.4 Left anterior fascicular block
0.704 0.296 0.000
K66 Other disorders of peritoneum
0.704 0.296 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.703 0.296 0.000
V10-V19 Pedal cyclist injured in transport accident
0.703 0.297 0.000
T51 Toxic effect of alcohol
0.700 0.299 0.000
E53 Deficiency of other B group vitamins
0.700 0.300 0.000
S00.1 Contusion of eyelid and periocular area
0.699 0.301 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.699 0.301 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.698 0.302 0.000
K09 Cysts of oral region, not elsewhere classified
0.695 0.305 0.000
R81 Glycosuria
0.695 0.305 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.695 0.305 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.692 0.308 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.691 0.309 0.000
E67 Other hyperalimentation
0.690 0.310 0.000
E68 Sequelae of hyperalimentation
0.690 0.310 0.000
E65 Localised adiposity
0.690 0.310 0.000
T87 Complications peculiar to reattachment and amputation
0.688 0.312 0.000
A80-A89 Viral infections of the central nervous system
0.688 0.312 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.687 0.313 0.000
V20-V29 Motorcycle rider injured in transport accident
0.687 0.313 0.000
B99-B99 Other infectious diseases
0.687 0.313 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.687 0.313 0.000
B65-B83 Helminthiases
0.687 0.313 0.000
B50-B64 Protozoal diseases
0.687 0.313 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.687 0.313 0.000
A75-A79 Rickettsioses
0.687 0.313 0.000
A70-A74 Other diseases caused by chlamydiae
0.687 0.313 0.000
A65-A69 Other spirochaetal diseases
0.687 0.313 0.000
A20-A28 Certain zoonotic bacterial diseases
0.687 0.313 0.000
A15-A19 Tuberculosis
0.687 0.313 0.000
O00-O08 Pregnancy with abortive outcome
0.687 0.313 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.687 0.313 0.000
I51.9 Heart disease, unspecified
0.687 0.313 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.686 0.314 0.000
R79 Other abnormal findings of blood chemistry
0.686 0.314 0.000
H01 Other inflammation of eyelid
0.685 0.315 0.000
H10-H13 Disorders of conjunctiva
0.684 0.316 0.000
B25 Cytomegaloviral disease
0.684 0.316 0.000
T86 Failure and rejection of transplanted organs and tissues
0.683 0.317 0.000
B02 Zoster [herpes zoster]
0.683 0.317 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.683 0.317 0.000
R49 Voice disturbances
0.682 0.318 0.000
S52 Fracture of forearm
0.682 0.318 0.000
I51.7 Cardiomegaly
0.682 0.318 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.682 0.318 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.681 0.318 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.681 0.319 0.000
V80-V89 Other land transport accidents
0.681 0.319 0.000
I67.1 Cerebral aneurysm, nonruptured
0.681 0.319 0.000
K12 Stomatitis and related lesions
0.680 0.320 0.000
I73 Other peripheral vascular diseases
0.679 0.321 0.000
F30-F39 Mood [affective] disorders
0.679 0.321 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.678 0.321 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.678 0.321 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.678 0.321 0.000
I65.1 Occlusion and stenosis of basilar artery
0.678 0.321 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.678 0.321 0.000
B15-B19 Viral hepatitis
0.678 0.322 0.000
Y40.0 Penicillins
0.678 0.322 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.678 0.322 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.678 0.322 0.000
E66.1 Drug-induced obesity
0.678 0.322 0.000
E66.0 Obesity due to excess calories
0.678 0.322 0.000
A00-A09 Intestinal infectious diseases
0.677 0.323 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.677 0.323 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.677 0.323 0.000
I45.1 Other and unspecified right bundle-branch block
0.676 0.324 0.000
S06.5 Traumatic subdural haemorrhage
0.675 0.325 0.000
K11 Diseases of salivary glands
0.674 0.326 0.000
R82 Other abnormal findings in urine
0.674 0.326 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.673 0.327 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.673 0.327 0.000
E63 Other nutritional deficiencies
0.673 0.327 0.000
E56 Other vitamin deficiencies
0.673 0.327 0.000
E51 Thiamine deficiency
0.673 0.327 0.000
E50 Vitamin A deficiency
0.673 0.327 0.000
E60 Dietary zinc deficiency
0.673 0.327 0.000
E59 Dietary selenium deficiency
0.673 0.327 0.000
E58 Dietary calcium deficiency
0.673 0.327 0.000
E54 Ascorbic acid deficiency
0.673 0.327 0.000
E52 Niacin deficiency [pellagra]
0.673 0.327 0.000
O66 Other obstructed labour
0.672 0.328 0.000
R29.4 Clicking hip
0.672 0.328 0.000
R29.3 Abnormal posture
0.672 0.328 0.000
R29.2 Abnormal reflex
0.672 0.328 0.000
R29.1 Meningismus
0.672 0.328 0.000
R29.0 Tetany
0.672 0.328 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.672 0.328 0.000
B33 Other viral diseases, not elsewhere classified
0.672 0.328 0.000
B30 Viral conjunctivitis
0.672 0.328 0.000
B27 Infectious mononucleosis
0.672 0.328 0.000
B26 Mumps
0.672 0.328 0.000
I45.5 Other specified heart block
0.672 0.328 0.000
Z60 Problems related to social environment
0.671 0.329 0.000
O63 Long labour
0.671 0.329 0.000
O71 Other obstetric trauma
0.670 0.330 0.000
R73 Elevated blood glucose level
0.668 0.332 0.000
E22 Hyperfunction of pituitary gland
0.668 0.332 0.000
R40 Somnolence, stupor and coma
0.668 0.332 0.000
R45.8 Other symptoms and signs involving emotional state
0.667 0.332 0.000
I42 Cardiomyopathy
0.667 0.333 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.667 0.333 0.000
K75 Other inflammatory liver diseases
0.666 0.334 0.000
K92 Other diseases of digestive system
0.666 0.334 0.000
S00.9 Superficial injury of head, part unspecified
0.666 0.334 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.664 0.335 0.000
Q80-Q89 Other congenital malformations
0.664 0.336 0.000
T92.1 Sequelae of fracture of arm
0.664 0.336 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.663 0.336 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.663 0.336 0.000
Y98 Lifestyle-related condition
0.663 0.336 0.000
Y97 Environmental-pollution-related condition
0.663 0.336 0.000
Y96 Work-related condition
0.663 0.336 0.000
Y44 Agents primarily affecting blood constituents
0.663 0.337 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.663 0.337 0.000
I33.9 Acute endocarditis, unspecified
0.661 0.339 0.000
B34.8 Other viral infections of unspecified site
0.661 0.339 0.000
B34.4 Papovirus infection, unspecified
0.661 0.339 0.000
B34.3 Parvovirus infection, unspecified
0.661 0.339 0.000
B34.2 Coronavirus infection, unspecified
0.661 0.339 0.000
B34.1 Enterovirus infection, unspecified
0.661 0.339 0.000
B34.0 Adenovirus infection, unspecified
0.661 0.339 0.000
I23 Certain current complications following acute myocardial infarction
0.660 0.340 0.000
H80-H83 Diseases of inner ear
0.659 0.340 0.000
I49 Other cardiac arrhythmias
0.659 0.341 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.659 0.341 0.000
Y52 Agents primarily affecting the cardiovascular system
0.659 0.341 0.000
I47.0 Reentry ventricular arrhythmia
0.658 0.342 0.000
Z63 Other problems related to primary support group, including family circumstances
0.658 0.342 0.000
S70-S79 Injuries to the hip and thigh
0.658 0.342 0.000
T82.1 Mechanical complication of cardiac electronic device
0.657 0.343 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.656 0.343 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.656 0.344 0.000
E29 Testicular dysfunction
0.655 0.345 0.000
R25 Abnormal involuntary movements
0.654 0.345 0.000
E27 Other disorders of adrenal gland
0.653 0.347 0.000
K76.9 Liver disease, unspecified
0.653 0.347 0.000
I31 Other diseases of pericardium
0.652 0.348 0.000
T93 Sequelae of injuries of lower limb
0.651 0.348 0.000
Q50-Q56 Congenital malformations of genital organs
0.651 0.349 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.651 0.349 0.000
R44.0 Auditory hallucinations
0.651 0.349 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.650 0.349 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.650 0.349 0.000
I67.5 Moyamoya disease
0.650 0.349 0.000
I67.4 Hypertensive encephalopathy
0.650 0.349 0.000
I67.3 Progressive vascular leukoencephalopathy
0.650 0.349 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.650 0.349 0.000
E21.3 Hyperparathyroidism, unspecified
0.650 0.350 0.000
H55-H59 Other disorders of eye and adnexa
0.649 0.350 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.649 0.351 0.000
T98 Sequelae of other and unspecified effects of external causes
0.649 0.351 0.000
T95 Sequelae of burns, corrosions and frostbite
0.649 0.351 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.649 0.351 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.649 0.351 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.649 0.351 0.000
K08 Other disorders of teeth and supporting structures
0.649 0.351 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.648 0.352 0.000
I46.9 Cardiac arrest, unspecified
0.648 0.352 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.647 0.353 0.000
Y88 Sequelae of surgical and medical care as external cause
0.647 0.353 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.647 0.353 0.000
Y59 Other and unspecified vaccines and biological substances
0.647 0.353 0.000
Y58 Bacterial vaccines
0.647 0.353 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.647 0.353 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.647 0.353 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.647 0.353 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.647 0.353 0.000
Y48 Anaesthetics and therapeutic gases
0.647 0.353 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.647 0.353 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.647 0.353 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.646 0.354 0.000
I05-I09 Chronic rheumatic heart diseases
0.645 0.355 0.000
Z50 Care involving use of rehabilitation procedures
0.645 0.355 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.645 0.355 0.000
R44.1 Visual hallucinations
0.643 0.357 0.000
Y40.8 Other systemic antibiotics
0.641 0.358 0.000
O72 Postpartum haemorrhage
0.641 0.359 0.000
B35-B49 Mycoses
0.641 0.359 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.640 0.360 0.000
I78 Diseases of capillaries
0.639 0.361 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.638 0.362 0.000
O62 Abnormalities of forces of labour
0.638 0.362 0.000
I70 Atherosclerosis
0.637 0.362 0.000
I71.0 Dissection of aorta [any part]
0.637 0.363 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.636 0.363 0.000
O16 Unspecified maternal hypertension
0.636 0.363 0.000
I27.0 Primary pulmonary hypertension
0.636 0.364 0.000
E55.0 Rickets, active
0.636 0.364 0.000
S06.2 Diffuse brain injury
0.636 0.364 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.635 0.365 0.000
I77 Other disorders of arteries and arterioles
0.635 0.365 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.635 0.365 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.634 0.366 0.000
O26.8 Other specified pregnancy-related conditions
0.634 0.366 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.634 0.366 0.000
H18 Other disorders of cornea
0.633 0.367 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.632 0.367 0.000
H60-H62 Diseases of external ear
0.632 0.368 0.000
E00-E07 Disorders of thyroid gland
0.632 0.368 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.632 0.368 0.000
Q35-Q37 Cleft lip and cleft palate
0.632 0.368 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.632 0.368 0.000
Q00-Q07 Congenital malformations of the nervous system
0.632 0.368 0.000
S02 Fracture of skull and facial bones
0.632 0.368 0.000
I51.6 Cardiovascular disease, unspecified
0.631 0.369 0.000
I51.5 Myocardial degeneration
0.631 0.369 0.000
I51.4 Myocarditis, unspecified
0.631 0.369 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.631 0.369 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.631 0.369 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.631 0.369 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.631 0.369 0.000
T51.0 Ethanol
0.630 0.370 0.000
K66.0 Peritoneal adhesions
0.629 0.371 0.000
I99 Other and unspecified disorders of circulatory system
0.629 0.371 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.629 0.371 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.628 0.372 0.000
K92.1 Melaena
0.628 0.372 0.000
S06.3 Focal brain injury
0.627 0.373 0.000
R36 Urethral discharge
0.627 0.373 0.000
R34 Anuria and oliguria
0.627 0.373 0.000
K65 Peritonitis
0.627 0.373 0.000
Z49 Care involving dialysis
0.626 0.374 0.000
R43.8 Other and unspecified disturbances of smell and taste
0.626 0.374 0.000
R32 Unspecified urinary incontinence
0.626 0.374 0.000
R45.1 Restlessness and agitation
0.626 0.374 0.000
T78 Adverse effects, not elsewhere classified
0.625 0.375 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.625 0.375 0.000
F99-F99 Unspecified mental disorder
0.624 0.376 0.000
I27.2 Other secondary pulmonary hypertension
0.624 0.376 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.624 0.376 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.623 0.377 0.000
Q21 Congenital malformations of cardiac septa
0.623 0.377 0.000
O28 Abnormal findings on antenatal screening of mother
0.623 0.377 0.000
Z34 Supervision of normal pregnancy
0.622 0.378 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.622 0.378 0.000
E21.0 Primary hyperparathyroidism
0.622 0.378 0.000
I46.0 Cardiac arrest with successful resuscitation
0.622 0.378 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.622 0.378 0.000
Y57 Other and unspecified drugs and medicaments
0.621 0.379 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.621 0.379 0.000
E34 Other endocrine disorders
0.621 0.379 0.000
E32 Diseases of thymus
0.621 0.379 0.000
E31 Polyglandular dysfunction
0.621 0.379 0.000
E30 Disorders of puberty, not elsewhere classified
0.621 0.379 0.000
E28 Ovarian dysfunction
0.621 0.379 0.000
E26 Hyperaldosteronism
0.621 0.379 0.000
E25 Adrenogenital disorders
0.621 0.379 0.000
E24 Cushing's syndrome
0.621 0.379 0.000
E20 Hypoparathyroidism
0.621 0.379 0.000
X58 Exposure to other specified factors
0.621 0.379 0.000
T40.4 Other synthetic narcotics
0.619 0.380 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.619 0.381 0.000
O90 Complications of the puerperium, not elsewhere classified
0.619 0.381 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.619 0.381 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.619 0.381 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.619 0.381 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.619 0.381 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.619 0.381 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.619 0.381 0.000
T36 Poisoning by systemic antibiotics
0.619 0.381 0.000
S50 Superficial injury of forearm
0.618 0.382 0.000
Z32 Pregnancy examination and test
0.617 0.383 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.615 0.385 0.000
K50-K52 Noninfective enteritis and colitis
0.615 0.385 0.000
I20 Angina pectoris
0.614 0.386 0.000
O23 Infections of genito-urinary tract in pregnancy
0.614 0.386 0.000
K07 Dentofacial anomalies [including malocclusion]
0.614 0.386 0.000
S00.5 Superficial injury of lip and oral cavity
0.613 0.387 0.000
S00.4 Superficial injury of ear
0.613 0.387 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.613 0.387 0.000
S91 Open wound of ankle and foot
0.611 0.388 0.000
I74 Arterial embolism and thrombosis
0.611 0.389 0.000
S00.7 Multiple superficial injuries of head
0.611 0.389 0.000
L40-L45 Papulosquamous disorders
0.611 0.389 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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