TreeWAS – Variant ID: rs78717951

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter II Neoplasms	0.999	0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001
M20-M25 Other joint disorders	0.999	0.001
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.999	0.001
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.998	0.002
Chapter XIV Diseases of the genitourinary system	0.997	0.003
R50-R69 General symptoms and signs	0.997	0.003
Chapter V Mental and behavioural disorders	0.996	0.004
N30-N39 Other diseases of urinary system	0.995	0.005
Chapter XX External causes of morbidity and mortality	0.993	0.007
N25-N29 Other disorders of kidney and ureter	0.992	0.008
R53 Malaise and fatigue	0.991	0.009
N28 Other disorders of kidney and ureter, not elsewhere classified	0.988	0.012
Chapter IV Endocrine, nutritional and metabolic diseases	0.985	0.015
Chapter I Certain infectious and parasitic diseases	0.984	0.016
Chapter XI Diseases of the digestive system	0.982	0.018
N28.1 Cyst of kidney, acquired	0.981	0.019
F00-F09 Organic, including symptomatic, mental disorders	0.980	0.020
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.978	0.022
C79 Secondary malignant neoplasm of other sites	0.978	0.022
C15-C26 Malignant neoplasms of digestive organs	0.974	0.026
K81 Cholecystitis	0.973	0.027
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.972	0.028
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.969	0.031
M25 Other joint disorders, not elsewhere classified	0.967	0.033
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.966	0.034
M23 Internal derangement of knee	0.964	0.036
E20-E35 Disorders of other endocrine glands	0.963	0.037
C16 Malignant neoplasm of stomach	0.963	0.037
B95-B98 Bacterial, viral and other infectious agents	0.962	0.038
F30-F39 Mood [affective] disorders	0.962	0.038
N32 Other disorders of bladder	0.960	0.040
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.958	0.042
M24 Other specific joint derangements	0.953	0.047
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.952	0.048
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.950	0.050
N30 Cystitis	0.949	0.051
M21 Other acquired deformities of limbs	0.949	0.051
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.948	0.052
N31.8 Other neuromuscular dysfunction of bladder	0.948	0.052
K81.9 Cholecystitis, unspecified	0.946	0.054
K86 Other diseases of pancreas	0.942	0.058
R51 Headache	0.932	0.068
E27 Other disorders of adrenal gland	0.932	0.068
M05-M14 Inflammatory polyarthropathies	0.928	0.072
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.928	0.072
C77.2 Intra-abdominal lymph nodes	0.923	0.077
M25.5 Pain in joint	0.922	0.078
F31 Bipolar affective disorder	0.919	0.081
R63 Symptoms and signs concerning food and fluid intake	0.918	0.082
K13 Other diseases of lip and oral mucosa	0.916	0.084
N32.3 Diverticulum of bladder	0.914	0.086
C16.9 Stomach, unspecified	0.911	0.089
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.908	0.092
E10-E14 Diabetes mellitus	0.902	0.098
K50-K52 Noninfective enteritis and colitis	0.902	0.098
F00 Dementia in Alzheimer's disease	0.900	0.100
E70-E90 Metabolic disorders	0.897	0.103
K11 Diseases of salivary glands	0.897	0.103
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.897	0.103
C80 Malignant neoplasm without specification of site	0.895	0.105
M25.57 Pain in joint (Ankle and foot)	0.894	0.106
W00-W19 Falls	0.894	0.106
K81.1 Chronic cholecystitis	0.891	0.109
M23.3 Other meniscus derangements	0.889	0.111
C77.5 Intrapelvic lymph nodes	0.888	0.112
E86 Volume depletion	0.884	0.116
K50 Crohn's disease [regional enteritis]	0.883	0.117
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.881	0.119
M86-M90 Other osteopathies	0.880	0.120
M06 Other rheumatoid arthritis	0.878	0.122
R21 Rash and other nonspecific skin eruption	0.877	0.123
M21.3 Wrist or foot drop (acquired)	0.875	0.125
N20-N23 Urolithiasis	0.875	0.125
Chapter XXI Factors influencing health status and contact with health services	0.875	0.125
N28.8 Other specified disorders of kidney and ureter	0.875	0.125
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.873	0.127
F05 Delirium, not induced by alcohol and other psychoactive substances	0.873	0.127
R20 Disturbances of skin sensation	0.871	0.129
R68 Other general symptoms and signs	0.871	0.129
F03 Unspecified dementia	0.870	0.130
C79.2 Secondary malignant neoplasm of skin	0.867	0.133
K86.8 Other specified diseases of pancreas	0.866	0.134
E27.1 Primary adrenocortical insufficiency	0.866	0.134
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.865	0.135
Z40-Z54 Persons encountering health services for specific procedures and health care	0.864	0.136
Z51 Other medical care	0.864	0.136
Z51.1 Chemotherapy session for neoplasm	0.863	0.137
R63.0 Anorexia	0.860	0.140
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.857	0.143
K12 Stomatitis and related lesions	0.855	0.145
C16.3 Pyloric antrum	0.853	0.147
S50-S59 Injuries to the elbow and forearm	0.852	0.148
A00-A09 Intestinal infectious diseases	0.851	0.149
N32.0 Bladder-neck obstruction	0.849	0.151
N32.9 Bladder disorder, unspecified	0.848	0.152
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.847	0.153
D37-D48 Neoplasms of uncertain or unknown behaviour	0.846	0.154
M06.9 Rheumatoid arthritis, unspecified	0.845	0.155
F00.9 Dementia in Alzheimer's disease, unspecified	0.843	0.157
M23.8 Other internal derangements of knee	0.843	0.157
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.840	0.160
C50-C50 Malignant neoplasm of breast	0.840	0.160
S52 Fracture of forearm	0.838	0.162
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.837	0.163
K50.1 Crohn's disease of large intestine	0.836	0.164
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.834	0.166
R50 Fever of unknown origin	0.830	0.170
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.830	0.170
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.829	0.171
M24.4 Recurrent dislocation and subluxation of joint	0.828	0.172
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.828	0.172
R57 Shock, not elsewhere classified	0.828	0.172
M60-M63 Disorders of muscles	0.827	0.172
F31.9 Bipolar affective disorder, unspecified	0.824	0.176
K13.7 Other and unspecified lesions of oral mucosa	0.824	0.176
N30.8 Other cystitis	0.823	0.177
F32 Depressive episode	0.823	0.177
Z50 Care involving use of rehabilitation procedures	0.823	0.177
K86.1 Other chronic pancreatitis	0.823	0.177
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.822	0.178
M23.30 Other meniscus derangements (Multiple sites)	0.822	0.178
M65-M68 Disorders of synovium and tendon	0.819	0.181
E34 Other endocrine disorders	0.816	0.184
N20 Calculus of kidney and ureter	0.816	0.184
M24.8 Other specific joint derangements, not elsewhere classified	0.814	0.186
C64-C68 Malignant neoplasms of urinary tract	0.813	0.187
K81.8 Other cholecystitis	0.813	0.187
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.812	0.188
K13.0 Diseases of lips	0.812	0.188
R29.6 Tendency to fall, not elsewhere classified	0.811	0.189
E27.2 Addisonian crisis	0.808	0.192
K86.0 Alcohol-induced chronic pancreatitis	0.807	0.193
S52.6 Fracture of lower end of both ulna and radius	0.807	0.193
M05 Seropositive rheumatoid arthritis	0.805	0.195
R61 Hyperhidrosis	0.805	0.195
R56 Convulsions, not elsewhere classified	0.802	0.198
R20.2 Paraesthesia of skin	0.802	0.198
W20-W49 Exposure to inanimate mechanical forces	0.802	0.198
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.802	0.198
K05 Gingivitis and periodontal diseases	0.802	0.198
K70-K77 Diseases of liver	0.802	0.198
M25.7 Osteophyte	0.801	0.199
R47-R49 Symptoms and signs involving speech and voice	0.800	0.200
N30.3 Trigonitis	0.800	0.200
M25.56 Pain in joint (Lower leg)	0.799	0.201
K11.2 Sialoadenitis	0.798	0.202
B25-B34 Other viral diseases	0.797	0.203
A30-A49 Other bacterial diseases	0.794	0.206
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.794	0.206
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.793	0.207
E10 Insulin-dependent diabetes mellitus	0.792	0.208
C16.5 Lesser curvature of stomach, unspecified	0.791	0.209
K12.1 Other forms of stomatitis	0.790	0.210
Chapter XXII Codes for special purposes	0.790	0.210
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.788	0.212
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.788	0.212
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.787	0.212
M35 Other systemic involvement of connective tissue	0.786	0.214
S52.60 Fracture of lower end of both ulna and radius (closed)	0.784	0.216
Y53 Agents primarily affecting the gastro-intestinal system	0.784	0.216
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.782	0.218
C16.2 Body of stomach	0.782	0.218
N30.9 Cystitis, unspecified	0.782	0.218
M89 Other disorders of bone	0.781	0.219
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.781	0.219
R68.8 Other specified general symptoms and signs	0.781	0.219
V20-V29 Motorcycle rider injured in transport accident	0.780	0.220
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.780	0.220
Y46 Antiepileptics and anti-Parkinsonism drugs	0.779	0.221
M21.6 Other acquired deformities of ankle and foot	0.779	0.221
C80.0 Malignant neoplasm, primary site unknown, so stated	0.778	0.222
M22 Disorders of patella	0.777	0.223
K85 Acute pancreatitis	0.776	0.224
R50.0 Fever with chills	0.776	0.224
C77.0 Lymph nodes of head, face and neck	0.776	0.224
T66-T78 Other and unspecified effects of external causes	0.773	0.227
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.773	0.227
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.773	0.227
Z51.8 Other specified medical care	0.773	0.227
M25.6 Stiffness of joint, not elsewhere classified	0.771	0.229
M25.3 Other instability of joint	0.770	0.230
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.770	0.230
Z43 Attention to artificial openings	0.770	0.230
K50.9 Crohn's disease, unspecified	0.769	0.231
N70-N77 Inflammatory diseases of female pelvic organs	0.769	0.231
M24.1 Other articular cartilage disorders	0.768	0.232
V40-V49 Car occupant injured in transport accident	0.768	0.232
A08 Viral and other specified intestinal infections	0.767	0.233
Y00-Y09 Assault	0.765	0.235
N30.0 Acute cystitis	0.764	0.236
K11.8 Other diseases of salivary glands	0.763	0.237
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.763	0.237
E88 Other metabolic disorders	0.761	0.239
M34 Systemic sclerosis	0.761	0.239
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.757	0.243
F05.9 Delirium, unspecified	0.756	0.244
C26 Malignant neoplasm of other and ill-defined digestive organs	0.756	0.244
Y57 Other and unspecified drugs and medicaments	0.754	0.246
C77.4 Inguinal and lower limb lymph nodes	0.753	0.247
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.753	0.247
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.752	0.248
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.750	0.250
M23.5 Chronic instability of knee	0.749	0.251
M25.59 Pain in joint (Site unspecified)	0.749	0.251
C17 Malignant neoplasm of small intestine	0.749	0.251
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.747	0.253
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.747	0.253
E23 Hypofunction and other disorders of pituitary gland	0.746	0.254
C78.7 Secondary malignant neoplasm of liver	0.744	0.256
Y95 Nosocomial condition	0.742	0.258
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.742	0.258
E14 Unspecified diabetes mellitus	0.741	0.259
F30 Manic episode	0.741	0.259
M24.2 Disorder of ligament	0.740	0.259
Y40 Systemic antibiotics	0.740	0.260
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.738	0.262
F29 Unspecified nonorganic psychosis	0.736	0.264
M13 Other arthritis	0.735	0.265
B20-B24 Human immunodeficiency virus [HIV] disease	0.735	0.265
Chapter XV Pregnancy, childbirth and the puerperium	0.734	0.266
M23.4 Loose body in knee	0.734	0.266
C67 Malignant neoplasm of bladder	0.734	0.266
C80.9 Malignant neoplasm, unspecified	0.733	0.267
N28.9 Disorder of kidney and ureter, unspecified	0.733	0.267
E13 Other specified diabetes mellitus	0.732	0.268
K50.0 Crohn's disease of small intestine	0.731	0.269
N34 Urethritis and urethral syndrome	0.730	0.270
S52.1 Fracture of upper end of radius	0.728	0.271
C79.7 Secondary malignant neoplasm of adrenal gland	0.728	0.272
F32.2 Severe depressive episode without psychotic symptoms	0.726	0.274
X40-X49 Accidental poisoning by and exposure to noxious substances	0.725	0.275
X60-X84 Intentional self-harm	0.725	0.275
C50 Malignant neoplasm of breast	0.725	0.275
C23 Malignant neoplasm of gallbladder	0.724	0.276
W08 Fall involving other furniture	0.724	0.276
E20 Hypoparathyroidism	0.723	0.277
K81.0 Acute cholecystitis	0.722	0.278
C15 Malignant neoplasm of oesophagus	0.722	0.278
M23.6 Other spontaneous disruption of ligament(s) of knee	0.722	0.278
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.722	0.278
W50-W64 Exposure to animate mechanical forces	0.722	0.278
M25.77 Osteophyte (Ankle and foot)	0.721	0.279
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.720	0.280
Z50.4 Psychotherapy, not elsewhere classified	0.720	0.280
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.719	0.281
C18 Malignant neoplasm of colon	0.719	0.281
A08.4 Viral intestinal infection, unspecified	0.718	0.282
W07 Fall involving chair	0.718	0.282
R52 Pain, not elsewhere classified	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
F60-F69 Disorders of adult personality and behaviour	0.717	0.283
M05.9 Seropositive rheumatoid arthritis, unspecified	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284
K82 Other diseases of gallbladder	0.716	0.284
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.716	0.284
M33 Dermatopolymyositis	0.716	0.284
M32 Systemic lupus erythematosus	0.716	0.284
M30 Polyarteritis nodosa and related conditions	0.716	0.284
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.716	0.284
C76 Malignant neoplasm of other and ill-defined sites	0.716	0.284
R95-R99 Ill-defined and unknown causes of mortality	0.716	0.284
E16 Other disorders of pancreatic internal secretion	0.715	0.285
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.715	0.285
R63.8 Other symptoms and signs concerning food and fluid intake	0.715	0.285
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.715	0.285
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.714	0.285
R62 Lack of expected normal physiological development	0.714	0.285
R64 Cachexia	0.714	0.285
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.714	0.286
Y51 Drugs primarily affecting the autonomic nervous system	0.714	0.286
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.714	0.286
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.714	0.286
F70-F79 Mental retardation	0.714	0.286
N37 Urethral disorders in diseases classified elsewhere	0.713	0.287
N33 Bladder disorders in diseases classified elsewhere	0.713	0.287
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.713	0.287
Y35-Y36 Legal intervention and operations of war	0.712	0.288
Y10-Y34 Event of undetermined intent	0.712	0.288
X85-X99 Assault	0.712	0.288
X58-X59 Accidental exposure to other and unspecified factors	0.712	0.288
X30-X39 Exposure to forces of nature	0.712	0.288
X20-X29 Contact with venomous animals and plants	0.712	0.288
X10-X19 Contact with heat and hot substances	0.712	0.288
X00-X09 Exposure to smoke, fire and flames	0.712	0.288
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.712	0.288
W75-W84 Other accidental threats to breathing	0.712	0.288
W65-W74 Accidental drowning and submersion	0.712	0.288
V98-V99 Other and unspecified transport accidents	0.712	0.288
V95-V97 Air and space transport accidents	0.712	0.288
V90-V94 Water transport accidents	0.712	0.288
V70-V79 Bus occupant injured in transport accident	0.712	0.288
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.712	0.288
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.712	0.288
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.712	0.288
V01-V09 Pedestrian injured in transport accident	0.712	0.288
Z51.4 Preparatory care for treatment, not elsewhere classified	0.712	0.288
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.712	0.288
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.712	0.288
E34.9 Endocrine disorder, unspecified	0.711	0.289
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.711	0.289
N27 Small kidney of unknown cause	0.711	0.289
N25 Disorders resulting from impaired renal tubular function	0.711	0.289
M67 Other disorders of synovium and tendon	0.711	0.289
M00-M03 Infectious arthropathies	0.711	0.289
F05.8 Other delirium	0.710	0.289
Z42 Follow-up care involving plastic surgery	0.710	0.290
M21.1 Varus deformity, not elsewhere classified	0.709	0.291
F01 Vascular dementia	0.709	0.291
N28.0 Ischaemia and infarction of kidney	0.708	0.291
C25 Malignant neoplasm of pancreas	0.708	0.291
N70 Salpingitis and oophoritis	0.708	0.292
E27.9 Disorder of adrenal gland, unspecified	0.708	0.292
B99-B99 Other infectious diseases	0.707	0.292
A04 Other bacterial intestinal infections	0.707	0.293
K13.6 Irritative hyperplasia of oral mucosa	0.707	0.293
B85-B89 Pediculosis, acariasis and other infestations	0.705	0.294
B50-B64 Protozoal diseases	0.705	0.294
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.705	0.294
A75-A79 Rickettsioses	0.705	0.294
A70-A74 Other diseases caused by chlamydiae	0.705	0.294
A65-A69 Other spirochaetal diseases	0.705	0.294
A20-A28 Certain zoonotic bacterial diseases	0.705	0.294
A15-A19 Tuberculosis	0.705	0.294
B65-B83 Helminthiases	0.705	0.295
M24.0 Loose body in joint	0.705	0.295
N20.1 Calculus of ureter	0.705	0.295
M62 Other disorders of muscle	0.705	0.295
X50-X57 Overexertion, travel and privation	0.704	0.296
Y45.2 Propionic acid derivatives	0.704	0.296
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.703	0.297
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.702	0.298
F02 Dementia in other diseases classified elsewhere	0.702	0.298
F09 Unspecified organic or symptomatic mental disorder	0.702	0.298
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.702	0.298
W13 Fall from, out of or through building or structure	0.702	0.298
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.701	0.298
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.701	0.299
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.701	0.299
C79.9 Secondary malignant neoplasm, unspecified site	0.701	0.299
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.700	0.300
N26 Unspecified contracted kidney	0.700	0.300
M25.8 Other specified joint disorders	0.700	0.300
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.700	0.300
Z51.0 Radiotherapy session	0.700	0.300
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.699	0.301
C21 Malignant neoplasm of anus and anal canal	0.699	0.301
R58 Haemorrhage, not elsewhere classified	0.698	0.301
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.697	0.303
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.697	0.303
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.697	0.303
C51-C58 Malignant neoplasms of female genital organs	0.697	0.303
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.696	0.304
M90 Osteopathies in diseases classified elsewhere	0.696	0.304
C16.0 Cardia	0.696	0.304
K07 Dentofacial anomalies [including malocclusion]	0.695	0.304
Y60-Y69 Misadventures to patients during surgical and medical care	0.694	0.306
C19 Malignant neoplasm of rectosigmoid junction	0.693	0.306
R57.2 Septic shock	0.693	0.307
M25.2 Flail joint	0.693	0.307
M25.1 Fistula of joint	0.693	0.307
Y59 Other and unspecified vaccines and biological substances	0.693	0.307
Y58 Bacterial vaccines	0.693	0.307
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.693	0.307
Y50 Central nervous system stimulants, not elsewhere classified	0.693	0.307
Y49 Psychotropic drugs, not elsewhere classified	0.693	0.307
Y48 Anaesthetics and therapeutic gases	0.693	0.307
Y47 Sedatives, hypnotics and antianxiety drugs	0.693	0.307
F99-F99 Unspecified mental disorder	0.693	0.307
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.691	0.309
E27.4 Other and unspecified adrenocortical insufficiency	0.691	0.309
V80-V89 Other land transport accidents	0.691	0.309
M23.9 Internal derangement of knee, unspecified	0.691	0.309
M23.1 Discoid meniscus (congenital)	0.691	0.309
M23.0 Cystic meniscus	0.691	0.309
E35 Disorders of endocrine glands in diseases classified elsewhere	0.690	0.310
E32 Diseases of thymus	0.690	0.310
E31 Polyglandular dysfunction	0.690	0.310
E30 Disorders of puberty, not elsewhere classified	0.690	0.310
E26 Hyperaldosteronism	0.690	0.310
E25 Adrenogenital disorders	0.690	0.310
E24 Cushing's syndrome	0.690	0.310
C16.8 Overlapping lesion of stomach	0.690	0.310
C16.6 Greater curvature of stomach, unspecified	0.690	0.310
C16.4 Pylorus	0.690	0.310
C16.1 Fundus of stomach	0.690	0.310
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.690	0.310
F38 Other mood [affective] disorders	0.689	0.310
F34 Persistent mood [affective] disorders	0.689	0.310
F39 Unspecified mood [affective] disorder	0.689	0.310
S52.0 Fracture of upper end of ulna	0.688	0.312
N32.4 Rupture of bladder, nontraumatic	0.688	0.312
N32.2 Vesical fistula, not elsewhere classified	0.688	0.312
Y45.8 Other analgesics and antipyretics	0.688	0.312
K03 Other diseases of hard tissues of teeth	0.687	0.313
K00 Disorders of tooth development and eruption	0.687	0.313
A80-A89 Viral infections of the central nervous system	0.687	0.313
E10.1 With ketoacidosis	0.687	0.313
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.685	0.315
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.685	0.315
N20.2 Calculus of kidney with calculus of ureter	0.685	0.315
E27.8 Other specified disorders of adrenal gland	0.684	0.316
S50 Superficial injury of forearm	0.684	0.316
R47 Speech disturbances, not elsewhere classified	0.684	0.316
F80-F89 Disorders of psychological development	0.684	0.316
F40-F48 Neurotic, stress-related and somatoform disorders	0.684	0.316
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.684	0.316
M24.5 Contracture of joint	0.684	0.316
M24.9 Joint derangement, unspecified	0.684	0.316
M24.7 Protrusio acetabuli	0.684	0.316
M24.6 Ankylosis of joint	0.684	0.316
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.684	0.316
Z50.0 Cardiac rehabilitation	0.683	0.317
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.683	0.317
M21.0 Valgus deformity, not elsewhere classified	0.683	0.317
S10-S19 Injuries to the neck	0.682	0.318
K86.3 Pseudocyst of pancreas	0.682	0.318
Y45.0 Opioids and related analgesics	0.681	0.319
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.681	0.319
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.681	0.319
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.681	0.319
N20.0 Calculus of kidney	0.681	0.319
N30.4 Irradiation cystitis	0.680	0.319
M21.9 Acquired deformity of limb, unspecified	0.680	0.320
M21.8 Other specified acquired deformities of limbs	0.680	0.320
M21.7 Unequal limb length (acquired)	0.680	0.320
M21.4 Flat foot [pes planus] (acquired)	0.680	0.320
M21.2 Flexion deformity	0.680	0.320
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.680	0.320
D41.4 Bladder	0.680	0.320
M35.3 Polymyalgia rheumatica	0.679	0.321
R27 Other lack of coordination	0.679	0.321
Z51.9 Medical care, unspecified	0.678	0.322
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.677	0.323
M25.51 Pain in joint (Shoulder region)	0.677	0.323
M25.0 Haemarthrosis	0.676	0.324
S90-S99 Injuries to the ankle and foot	0.676	0.324
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.676	0.324
Z50.1 Other physical therapy	0.675	0.325
M89.8 Other specified disorders of bone	0.675	0.325
K08 Other disorders of teeth and supporting structures	0.675	0.325
Z63 Other problems related to primary support group, including family circumstances	0.675	0.325
K11.5 Sialolithiasis	0.675	0.325
W06 Fall involving bed	0.675	0.325
Y52 Agents primarily affecting the cardiovascular system	0.674	0.326
S70-S79 Injuries to the hip and thigh	0.674	0.326
N99-N99 Other disorders of the genitourinary system	0.673	0.326
V10-V19 Pedal cyclist injured in transport accident	0.673	0.326
M06.3 Rheumatoid nodule	0.673	0.327
N30.2 Other chronic cystitis	0.672	0.328
R23 Other skin changes	0.672	0.328
R46 Symptoms and signs involving appearance and behaviour	0.672	0.328
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.671	0.329
Q50-Q56 Congenital malformations of genital organs	0.671	0.329
B90-B94 Sequelae of infectious and parasitic diseases	0.670	0.329
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.669	0.330
T00-T07 Injuries involving multiple body regions	0.669	0.331
C18.0 Caecum	0.669	0.331
E29 Testicular dysfunction	0.668	0.332
E27.5 Adrenomedullary hyperfunction	0.668	0.332
E27.3 Drug-induced adrenocortical insufficiency	0.668	0.332
E27.0 Other adrenocortical overactivity	0.668	0.332
N21 Calculus of lower urinary tract	0.668	0.332
K10 Other diseases of jaws	0.668	0.332
R61.9 Hyperhidrosis, unspecified	0.667	0.333
W18 Other fall on same level	0.667	0.333
Y45.1 Salicylates	0.666	0.334
M14 Arthropathies in other diseases classified elsewhere	0.666	0.334
M12 Other specific arthropathies	0.666	0.334
M09 Juvenile arthritis in diseases classified elsewhere	0.666	0.334
M08 Juvenile arthritis	0.666	0.334
R29.4 Clicking hip	0.665	0.335
R29.3 Abnormal posture	0.665	0.335
R29.2 Abnormal reflex	0.665	0.335
R29.1 Meningismus	0.665	0.335
R29.0 Tetany	0.665	0.335
N36 Other disorders of urethra	0.665	0.335
E10.5 With peripheral circulatory complications	0.665	0.335
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.664	0.335
Z43.5 Attention to cyctostomy	0.664	0.336
M91-M94 Chondropathies	0.664	0.336
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.664	0.336
R20.8 Other and unspecified disturbances of skin sensation	0.664	0.336
N30.1 Interstitial cystitis (chronic)	0.664	0.336
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.663	0.337
K73 Chronic hepatitis, not elsewhere classified	0.663	0.337
R56.8 Other and unspecified convulsions	0.663	0.337
E22 Hyperfunction of pituitary gland	0.663	0.337
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.662	0.338
M25.58 Pain in joint (Other)	0.661	0.339
M25.52 Pain in joint (Upper arm)	0.661	0.339
Y44 Agents primarily affecting blood constituents	0.661	0.339
E85 Amyloidosis	0.661	0.339
K09 Cysts of oral region, not elsewhere classified	0.661	0.339
C77.3 Axillary and upper limb lymph nodes	0.661	0.339
B15-B19 Viral hepatitis	0.660	0.339
K76 Other diseases of liver	0.660	0.340
B34 Viral infection of unspecified site	0.659	0.341
F31.8 Other bipolar affective disorders	0.659	0.341

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations