TreeWAS – Variant ID: rs78730305

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter VI Diseases of the nervous system	1.000	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.999	0.001
Chapter XV Pregnancy, childbirth and the puerperium	0.999	0.001
Chapter XX External causes of morbidity and mortality	0.998	0.002
G62 Other polyneuropathies	0.995	0.005
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.991	0.009
G62.9 Polyneuropathy, unspecified	0.990	0.010
Chapter IV Endocrine, nutritional and metabolic diseases	0.988	0.012
E10-E14 Diabetes mellitus	0.984	0.016
Chapter I Certain infectious and parasitic diseases	0.984	0.016
G20-G26 Extrapyramidal and movement disorders	0.980	0.020
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.979	0.021
D70-D77 Other diseases of blood and blood-forming organs	0.977	0.023
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.976	0.024
Chapter VIII Diseases of the ear and mastoid process	0.975	0.025
O60-O75 Complications of labour and delivery	0.974	0.026
D70 Agranulocytosis	0.972	0.028
G20 Parkinson's disease	0.963	0.037
H60-H62 Diseases of external ear	0.958	0.042
O75 Other complications of labour and delivery, not elsewhere classified	0.947	0.053
Chapter X Diseases of the respiratory system	0.946	0.054
H61 Other disorders of external ear	0.944	0.056
E10 Insulin-dependent diabetes mellitus	0.941	0.059
J95-J99 Other diseases of the respiratory system	0.939	0.061
G80-G83 Cerebral palsy and other paralytic syndromes	0.937	0.063
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.936	0.064
O94-O99 Other obstetric conditions, not elsewhere classified	0.934	0.066
S70-S79 Injuries to the hip and thigh	0.931	0.069
J98 Other respiratory disorders	0.931	0.069
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.923	0.077
A30-A49 Other bacterial diseases	0.922	0.078
E14 Unspecified diabetes mellitus	0.919	0.081
G63 Polyneuropathy in diseases classified elsewhere	0.918	0.082
S60-S69 Injuries to the wrist and hand	0.912	0.088
J98.1 Pulmonary collapse	0.909	0.091
J98.0 Diseases of bronchus, not elsewhere classified	0.897	0.103
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.888	0.112
H61.0 Perichondritis of external ear	0.884	0.116
E11 Non-insulin-dependent diabetes mellitus	0.884	0.116
W00-W19 Falls	0.881	0.119
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.881	0.119
E00-E07 Disorders of thyroid gland	0.878	0.122
G81 Hemiplegia	0.878	0.122
O62 Abnormalities of forces of labour	0.878	0.122
O20-O29 Other maternal disorders predominantly related to pregnancy	0.877	0.123
G70-G73 Diseases of myoneural junction and muscle	0.874	0.126
Chapter XII Diseases of the skin and subcutaneous tissue	0.869	0.131
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.867	0.133
A00-A09 Intestinal infectious diseases	0.867	0.133
G61 Inflammatory polyneuropathy	0.865	0.135
G40-G47 Episodic and paroxysmal disorders	0.863	0.137
G63.2 Diabetic polyneuropathy	0.861	0.139
Y52 Agents primarily affecting the cardiovascular system	0.860	0.140
J80-J84 Other respiratory diseases principally affecting the interstitium	0.858	0.142
H61.8 Other specified disorders of external ear	0.855	0.145
L00-L08 Infections of the skin and subcutaneous tissue	0.852	0.148
T66-T78 Other and unspecified effects of external causes	0.846	0.154
B25-B34 Other viral diseases	0.844	0.156
Y43 Primarily systemic agents	0.843	0.157
S70 Superficial injury of hip and thigh	0.842	0.158
D75 Other diseases of blood and blood-forming organs	0.840	0.160
T20-T25 Burns and corrosions of external body surface, specified by site	0.839	0.161
W20-W49 Exposure to inanimate mechanical forces	0.838	0.162
O61 Failed induction of labour	0.838	0.162
A49 Bacterial infection of unspecified site	0.837	0.163
E10.3 With ophthalmic complications	0.835	0.165
Y86 Sequelae of other accidents	0.834	0.166
L03 Cellulitis	0.833	0.167
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.830	0.170
G00-G09 Inflammatory diseases of the central nervous system	0.830	0.170
S10-S19 Injuries to the neck	0.829	0.170
Q20-Q28 Congenital malformations of the circulatory system	0.829	0.171
O75.0 Maternal distress during labour and delivery	0.828	0.172
E10.1 With ketoacidosis	0.826	0.174
O69 Labour and delivery complicated by umbilical cord complications	0.825	0.175
W13 Fall from, out of or through building or structure	0.823	0.177
E14.3 With ophthalmic complications	0.822	0.178
A50-A64 Infections with a predominantly sexual mode of transmission	0.820	0.180
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.815	0.185
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.814	0.186
G62.8 Other specified polyneuropathies	0.811	0.189
E11.4 With neurological complications	0.811	0.189
E10.4 With neurological complications	0.809	0.191
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.809	0.191
G30-G32 Other degenerative diseases of the nervous system	0.808	0.192
G81.9 Hemiplegia, unspecified	0.805	0.195
O75.8 Other specified complications of labour and delivery	0.802	0.197
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.801	0.199
J40-J47 Chronic lower respiratory diseases	0.800	0.200
L03.0 Cellulitis of finger and toe	0.800	0.200
T79-T79 Certain early complications of trauma	0.797	0.203
E11.0 With coma	0.797	0.203
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.796	0.204
Y60-Y69 Misadventures to patients during surgical and medical care	0.795	0.205
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.793	0.207
O72 Postpartum haemorrhage	0.793	0.207
L03.2 Cellulitis of face	0.790	0.210
A40 Streptococcal septicaemia	0.787	0.213
H61.9 Disorder of external ear, unspecified	0.787	0.213
Q60-Q64 Congenital malformations of the urinary system	0.786	0.214
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.786	0.214
G72 Other myopathies	0.785	0.215
Y88 Sequelae of surgical and medical care as external cause	0.785	0.215
G25 Other extrapyramidal and movement disorders	0.784	0.216
S72 Fracture of femur	0.783	0.217
O85-O92 Complications predominantly related to the puerperium	0.783	0.217
S61 Open wound of wrist and hand	0.783	0.217
Y40 Systemic antibiotics	0.782	0.218
S62 Fracture at wrist and hand level	0.782	0.218
W13.9 Unspecified place	0.781	0.219
X40-X49 Accidental poisoning by and exposure to noxious substances	0.780	0.220
O75.7 Vaginal delivery following previous Caesarean section	0.780	0.220
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.775	0.225
E04 Other non-toxic goitre	0.774	0.226
S70.1 Contusion of thigh	0.774	0.226
B35-B49 Mycoses	0.771	0.229
S68 Traumatic amputation of wrist and hand	0.771	0.229
E13 Other specified diabetes mellitus	0.770	0.230
X58-X59 Accidental exposure to other and unspecified factors	0.769	0.231
O62.2 Other uterine inertia	0.766	0.234
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.765	0.235
T15-T19 Effects of foreign body entering through natural orifice	0.764	0.236
O20 Haemorrhage in early pregnancy	0.764	0.236
D72 Other disorders of white blood cells	0.764	0.236
J80 Adult respiratory distress syndrome	0.763	0.237
S90-S99 Injuries to the ankle and foot	0.762	0.238
G82 Paraplegia and tetraplegia	0.761	0.239
Y52.4 Angiotensin-converting-enzyme inhibitors	0.760	0.240
X10-X19 Contact with heat and hot substances	0.758	0.242
T78 Adverse effects, not elsewhere classified	0.758	0.242
J95 Postprocedural respiratory disorders, not elsewhere classified	0.757	0.243
G44 Other headache syndromes	0.757	0.243
O41 Other disorders of amniotic fluid and membranes	0.755	0.245
J44 Other chronic obstructive pulmonary disease	0.754	0.246
O75.2 Pyrexia during labour, not elsewhere classified	0.754	0.246
X60-X84 Intentional self-harm	0.752	0.248
T00-T07 Injuries involving multiple body regions	0.751	0.249
K51 Ulcerative colitis	0.749	0.251
A65-A69 Other spirochaetal diseases	0.749	0.251
X50-X57 Overexertion, travel and privation	0.749	0.251
J44.9 Chronic obstructive pulmonary disease, unspecified	0.748	0.252
B50-B64 Protozoal diseases	0.747	0.253
E11.1 With ketoacidosis	0.746	0.254
W50-W64 Exposure to animate mechanical forces	0.746	0.254
O71 Other obstetric trauma	0.745	0.255
O21 Excessive vomiting in pregnancy	0.745	0.255
S71 Open wound of hip and thigh	0.745	0.255
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.745	0.255
D80-D89 Certain disorders involving the immune mechanism	0.745	0.255
E14.9 Without complications	0.745	0.255
E05 Thyrotoxicosis [hyperthyroidism]	0.744	0.256
X20-X29 Contact with venomous animals and plants	0.743	0.257
Y43.3 Other antineoplastic drugs	0.742	0.258
A49.0 Staphylococcal infection, unspecified	0.742	0.258
O61.0 Failed medical induction of labour	0.740	0.260
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.740	0.260
S80-S89 Injuries to the knee and lower leg	0.739	0.261
L02 Cutaneous abscess, furuncle and carbuncle	0.737	0.263
K51.9 Ulcerative colitis, unspecified	0.736	0.264
S20-S29 Injuries to the thorax	0.735	0.265
G61.0 Guillain-Barre syndrome	0.735	0.265
G81.1 Spastic hemiplegia	0.734	0.266
Y48 Anaesthetics and therapeutic gases	0.734	0.266
O66 Other obstructed labour	0.733	0.267
E14.4 With neurological complications	0.732	0.268
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.731	0.269
H60 Otitis externa	0.730	0.270
A49.1 Streptococcal infection, unspecified	0.725	0.275
O16 Unspecified maternal hypertension	0.724	0.276
V80-V89 Other land transport accidents	0.724	0.276
V40-V49 Car occupant injured in transport accident	0.724	0.276
W06 Fall involving bed	0.724	0.276
B34 Viral infection of unspecified site	0.724	0.276
L50-L54 Urticaria and erythema	0.723	0.277
H61.1 Non-infective disorders of pinna	0.723	0.277
D73 Diseases of spleen	0.723	0.277
O30 Multiple gestation	0.723	0.277
G41 Status epilepticus	0.721	0.279
B90-B94 Sequelae of infectious and parasitic diseases	0.721	0.279
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.720	0.280
E10.0 With coma	0.719	0.281
A46 Erysipelas	0.718	0.282
K50-K52 Noninfective enteritis and colitis	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
O62.3 Precipitate labour	0.717	0.283
G64 Other disorders of peripheral nervous system	0.716	0.284
Y35-Y36 Legal intervention and operations of war	0.716	0.284
Y10-Y34 Event of undetermined intent	0.716	0.284
Y00-Y09 Assault	0.716	0.284
X85-X99 Assault	0.716	0.284
X30-X39 Exposure to forces of nature	0.716	0.284
X00-X09 Exposure to smoke, fire and flames	0.716	0.284
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.716	0.284
W75-W84 Other accidental threats to breathing	0.716	0.284
W65-W74 Accidental drowning and submersion	0.716	0.284
V98-V99 Other and unspecified transport accidents	0.716	0.284
V95-V97 Air and space transport accidents	0.716	0.284
V90-V94 Water transport accidents	0.716	0.284
V70-V79 Bus occupant injured in transport accident	0.716	0.284
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.716	0.284
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.716	0.284
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.716	0.284
V01-V09 Pedestrian injured in transport accident	0.716	0.284
G62.2 Polyneuropathy due to other toxic agents	0.713	0.287
G62.1 Alcoholic polyneuropathy	0.713	0.287
H80-H83 Diseases of inner ear	0.713	0.287
H61.3 Acquired stenosis of external ear canal	0.712	0.288
Y57 Other and unspecified drugs and medicaments	0.711	0.289
T33-T35 Frostbite	0.710	0.290
T26-T28 Burns and corrosions confined to eye and internal organs	0.710	0.290
H65-H75 Diseases of middle ear and mastoid	0.708	0.292
Q61 Cystic kidney disease	0.708	0.292
S61.8 Open wound of other parts of wrist and hand	0.708	0.292
J84 Other interstitial pulmonary diseases	0.707	0.293
J98.6 Disorders of diaphragm	0.707	0.293
E12 Malnutrition-related diabetes mellitus	0.706	0.294
B85-B89 Pediculosis, acariasis and other infestations	0.706	0.294
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.706	0.294
A75-A79 Rickettsioses	0.706	0.294
A70-A74 Other diseases caused by chlamydiae	0.706	0.294
A20-A28 Certain zoonotic bacterial diseases	0.706	0.294
A15-A19 Tuberculosis	0.706	0.294
W18 Other fall on same level	0.706	0.294
W22 Striking against or struck by other objects	0.705	0.295
D75.2 Essential thrombocytosis	0.705	0.295
Q21 Congenital malformations of cardiac septa	0.704	0.296
G83 Other paralytic syndromes	0.704	0.296
Y89 Sequelae of other external causes	0.703	0.297
O45 Premature separation of placenta [abruptio placentae]	0.703	0.297
Y85 Sequelae of transport accidents	0.703	0.297
G23 Other degenerative diseases of basal ganglia	0.703	0.297
G21 Secondary Parkinsonism	0.703	0.297
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.703	0.297
G22 Parkinsonism in diseases classified elsewhere	0.703	0.297
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.702	0.298
B20-B24 Human immunodeficiency virus [HIV] disease	0.701	0.299
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.700	0.299
D74 Methaemoglobinaemia	0.700	0.299
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.700	0.299
D71 Functional disorders of polymorphonuclear neutrophils	0.700	0.299
Chapter XXII Codes for special purposes	0.700	0.300
O64 Obstructed labour due to malposition and malpresentation of foetus	0.700	0.300
Y59 Other and unspecified vaccines and biological substances	0.700	0.300
Y58 Bacterial vaccines	0.700	0.300
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.700	0.300
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.700	0.300
Y53 Agents primarily affecting the gastro-intestinal system	0.700	0.300
Y50 Central nervous system stimulants, not elsewhere classified	0.700	0.300
Y49 Psychotropic drugs, not elsewhere classified	0.700	0.300
Y47 Sedatives, hypnotics and antianxiety drugs	0.700	0.300
Y46 Antiepileptics and anti-Parkinsonism drugs	0.700	0.300
V20-V29 Motorcycle rider injured in transport accident	0.700	0.300
Chapter XI Diseases of the digestive system	0.698	0.302
B99-B99 Other infectious diseases	0.698	0.302
O74 Complications of anaesthesia during labour and delivery	0.698	0.302
O65 Obstructed labour due to maternal pelvic abnormality	0.698	0.302
O60 Preterm delivery	0.698	0.302
G44.2 Tension-type headache	0.697	0.303
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.696	0.304
O40 Polyhydramnios	0.696	0.304
O69.8 Labour and delivery complicated by other cord complications	0.694	0.306
E10.5 With peripheral circulatory complications	0.693	0.307
B95-B98 Bacterial, viral and other infectious agents	0.692	0.308
S50-S59 Injuries to the elbow and forearm	0.692	0.308
T98 Sequelae of other and unspecified effects of external causes	0.690	0.310
G62.0 Drug-induced polyneuropathy	0.690	0.310
E16 Other disorders of pancreatic internal secretion	0.689	0.311
V10-V19 Pedal cyclist injured in transport accident	0.688	0.312
E06 Thyroiditis	0.688	0.312
J60-J70 Lung diseases due to external agents	0.687	0.313
H62 Disorders of external ear in diseases classified elsewhere	0.687	0.313
D75.8 Other specified diseases of blood and blood-forming organs	0.687	0.313
S61.0 Open wound of finger(s) without damage to nail	0.687	0.313
J98.9 Respiratory disorder, unspecified	0.686	0.314
A08 Viral and other specified intestinal infections	0.686	0.314
G06 Intracranial and intraspinal abscess and granuloma	0.686	0.314
S40-S49 Injuries to the shoulder and upper arm	0.686	0.314
G72.9 Myopathy, unspecified	0.685	0.315
A02 Other Salmonella infections	0.685	0.315
G61.8 Other inflammatory polyneuropathies	0.684	0.316
S72.1 Pertrochanteric fracture	0.684	0.316
Y51 Drugs primarily affecting the autonomic nervous system	0.684	0.316
A04 Other bacterial intestinal infections	0.682	0.318
Y40.0 Penicillins	0.680	0.320
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.680	0.320
A40.3 Septicaemia due to Streptococcus pneumoniae	0.679	0.321
O75.9 Complication of labour and delivery, unspecified	0.679	0.321
O75.5 Delayed delivery after artificial rupture of membranes	0.679	0.321
O75.4 Other complications of obstetric surgery and procedures	0.679	0.321
O75.3 Other infection during labour	0.679	0.321
O75.1 Shock during or following labour and delivery	0.679	0.321
T31 Burns classified according to extent of body surface involved	0.678	0.322
E11.2 With renal complications	0.677	0.323
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.676	0.324
K51.5 Mucosal proctocolitis	0.676	0.324
K51.2 Ulcerative (chronic) proctitis	0.676	0.324
D75.9 Disease of blood and blood-forming organs, unspecified	0.675	0.325
O24 Diabetes mellitus in pregnancy	0.675	0.325
E10.8 With unspecified complications	0.674	0.325
E10.7 With multiple complications	0.674	0.325
E10.6 With other specified complications	0.674	0.325
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.674	0.326
L03.3 Cellulitis of trunk	0.674	0.326
S80 Superficial injury of lower leg	0.673	0.327
J96 Respiratory failure, not elsewhere classified	0.673	0.327
L05 Pilonidal cyst	0.672	0.328
Q28 Other congenital malformations of circulatory system	0.671	0.329
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.671	0.329
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.671	0.329
J99 Respiratory disorders in diseases classified elsewhere	0.671	0.329
W17 Other fall from one level to another	0.670	0.330
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.670	0.330
O97 Death from sequelae of direct obstetric causes	0.670	0.330
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.670	0.330
O95 Obstetric death of unspecified cause	0.670	0.330
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.670	0.330
O34 Maternal care for known or suspected abnormality of pelvic organs	0.670	0.330
G24 Dystonia	0.668	0.332
S78 Traumatic amputation of hip and thigh	0.668	0.332
S77 Crushing injury of hip and thigh	0.668	0.332
S76 Injury of muscle and tendon at hip and thigh level	0.668	0.332
S75 Injury of blood vessels at hip and thigh level	0.668	0.332
S74 Injury of nerves at hip and thigh level	0.668	0.332
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.668	0.332
E40-E46 Malnutrition	0.667	0.332
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.667	0.332
J98.5 Diseases of mediastinum, not elsewhere classified	0.667	0.333
J98.3 Compensatory emphysema	0.667	0.333
J98.2 Interstitial emphysema	0.667	0.333
B15-B19 Viral hepatitis	0.666	0.334
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.666	0.334
O41.0 Oligohydramnios	0.665	0.334
A07 Other protozoal intestinal diseases	0.665	0.335
B37 Candidiasis	0.665	0.335
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.664	0.335
S66 Injury of muscle and tendon at wrist and hand level	0.664	0.336
D55-D59 Haemolytic anaemias	0.664	0.336
Q50-Q56 Congenital malformations of genital organs	0.663	0.336
J46 Status asthmaticus	0.663	0.337
Y42.5 Other oestrogens and progestogens	0.663	0.337
Y52.1 Calcium-channel blockers	0.663	0.337
O44 Placenta praevia	0.662	0.338
J95.8 Other postprocedural respiratory disorders	0.662	0.338
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.661	0.338
Q35-Q37 Cleft lip and cleft palate	0.661	0.338
Q30-Q34 Congenital malformations of the respiratory system	0.661	0.338
A44 Bartonellosis	0.661	0.339
A43 Nocardiosis	0.661	0.339
A42 Actinomycosis	0.661	0.339
A39 Meningococcal infection	0.661	0.339
A37 Whooping cough	0.661	0.339
A36 Diphtheria	0.661	0.339
A32 Listeriosis	0.661	0.339
A31 Infection due to other mycobacteria	0.661	0.339
A30 Leprosy [Hansen's disease]	0.661	0.339
A38 Scarlet fever	0.661	0.339
A35 Other tetanus	0.661	0.339
A34 Obstetrical tetanus	0.661	0.339
A33 Tetanus neonatorum	0.661	0.339
S12 Fracture of neck	0.661	0.339
A48 Other bacterial diseases, not elsewhere classified	0.660	0.339
H90-H95 Other disorders of ear	0.660	0.340
E14.8 With unspecified complications	0.659	0.341
E14.7 With multiple complications	0.659	0.341
E14.6 With other specified complications	0.659	0.341
E14.5 With peripheral circulatory complications	0.659	0.341
E14.2 Withrenal complications	0.659	0.341
E14.1 With ketoacidosis	0.659	0.341
E14.0 With coma	0.659	0.341
G71 Primary disorders of muscles	0.659	0.341
G63.8 Polyneuropathy in other diseases classified elsewhere	0.658	0.341
G63.6 Polyneuropathy in other musculoskeletal disorders	0.658	0.341
G63.5 Polyneuropathy in systemic connective tissue disorders	0.658	0.341
G63.4 Polyneuropathy in nutritional deficiency	0.658	0.341
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.658	0.341
G63.1 Polyneuropathy in neoplastic disease	0.658	0.341
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.658	0.341
T79 Certain early complications of trauma, not elsewhere classified	0.658	0.342
G43 Migraine	0.658	0.342
S65 Injury of blood vessels at wrist and hand level	0.658	0.342
O72.1 Other immediate postpartum haemorrhage	0.657	0.343
Q38-Q45 Other congenital malformations of the digestive system	0.657	0.343
J82 Pulmonary eosinophilia, not elsewhere classified	0.657	0.343
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.656	0.344
O69.0 Labour and delivery complicated by prolapse of cord	0.655	0.345
T20 Burn and corrosion of head and neck	0.654	0.346
G60 Hereditary and idiopathic neuropathy	0.654	0.346
B27 Infectious mononucleosis	0.654	0.346
L10-L14 Bullous disorders	0.653	0.347
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.653	0.347
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.653	0.347
K51.8 Other ulcerative colitis	0.653	0.347
O35 Maternal care for known or suspected foetal abnormality and damage	0.652	0.348
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.650	0.350
G25.3 Myoclonus	0.649	0.351
W29 Contact with other powered hand tools and household machinery	0.649	0.351
S19 Other and unspecified injuries of neck	0.649	0.351
O69.9 Labour and delivery complicated by cord complication, unspecified	0.649	0.351
G47 Sleep disorders	0.648	0.352
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.648	0.352
A80-A89 Viral infections of the central nervous system	0.647	0.353
E05.9 Thyrotoxicosis, unspecified	0.647	0.353
Y44 Agents primarily affecting blood constituents	0.647	0.353
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.645	0.355
T94 Sequelae of injuries involving multiple and unspecified body regions	0.645	0.355
E11.3 With ophthalmic complications	0.644	0.356
E04.1 Non-toxic single thyroid nodule	0.644	0.356
G72.0 Drug-induced myopathy	0.644	0.356
K51.4 Pseudopolyposis of colon	0.643	0.357
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.643	0.357
L03.9 Cellulitis, unspecified	0.641	0.359
Q27 Other congenital malformations of peripheral vascular system	0.641	0.359
T23 Burn and corrosion of wrist and hand	0.641	0.359
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.641	0.359
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.641	0.359
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.640	0.360
G03 Meningitis due to other and unspecified causes	0.639	0.361
B34.9 Viral infection, unspecified	0.639	0.361
S92 Fracture of foot, except ankle	0.639	0.361
B65-B83 Helminthiases	0.639	0.361
T78.2 Anaphylactic shock, unspecified	0.639	0.361
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.639	0.361
O20.0 Threatened abortion	0.638	0.362
S72.3 Fracture of shaft of femur	0.638	0.362
T78.3 Angioneurotic oedema	0.637	0.363
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.637	0.363
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.637	0.363
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.637	0.363
S62.5 Fracture of thumb	0.636	0.364
O90 Complications of the puerperium, not elsewhere classified	0.635	0.365
S14 Injury of nerves and spinal cord at neck level	0.634	0.365
E11.6 With other specified complications	0.634	0.366
E11.7 With multiple complications	0.634	0.366
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.634	0.366
G25.0 Essential tremor	0.632	0.368
W16 Diving or jumping into water causing injury other than drowning or submersion	0.632	0.368
W15 Fall from cliff	0.632	0.368
W14 Fall from tree	0.632	0.368
W12 Fall on and from scaffolding	0.632	0.368
W11 Fall on and from ladder	0.632	0.368
W09 Fall involving playground equipment	0.632	0.368
W05 Fall involving wheelchair	0.632	0.368
W04 Fall while being carried or supported by other persons	0.632	0.368
W03 Other fall on same level due to collision with, or pushing by, another person	0.632	0.368
W01 Fall on same level from slipping, tripping and stumbling	0.632	0.368
W00 Fall on same level involving ice and snow	0.632	0.368
Y43.4 Immunosuppressive agents	0.631	0.368
O15 Eclampsia	0.631	0.369
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.631	0.369
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.631	0.369
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.630	0.370
E00 Congenital iodine-deficiency syndrome	0.630	0.370
E02 Subclinical iodine-deficiency hypothyroidism	0.630	0.370
G81.0 Flaccid hemiplegia	0.630	0.370
O62.9 Abnormality of forces of labour, unspecified	0.629	0.371
O62.8 Other abnormalities of forces of labour	0.629	0.371
O62.1 Secondary uterine inertia	0.629	0.371
O62.0 Primary inadequate contractions	0.629	0.371
K50 Crohn's disease [regional enteritis]	0.629	0.371
J47 Bronchiectasis	0.629	0.371
O29 Complications of anaesthesia during pregnancy	0.629	0.371
O28 Abnormal findings on antenatal screening of mother	0.629	0.371
O22 Venous complications in pregnancy	0.629	0.371
O25 Malnutrition in pregnancy	0.629	0.371
S80.9 Superficial injury of lower leg, unspecified	0.628	0.372
T92 Sequelae of injuries of upper limb	0.628	0.372
L60-L75 Disorders of skin appendages	0.627	0.373
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.626	0.373
W10 Fall on and from stairs and steps	0.625	0.374
E11.8 With unspecified complications	0.625	0.375
W08 Fall involving other furniture	0.625	0.375
Y54.4 Loop [high-ceiling] diuretics	0.624	0.376
Y45.0 Opioids and related analgesics	0.622	0.378
O33 Maternal care for known or suspected disproportion	0.622	0.378
O31 Complications specific to multiple gestation	0.622	0.378
A06 Amoebiasis	0.621	0.378
A05 Other bacterial foodborne intoxications	0.621	0.378
A03 Shigellosis	0.621	0.378
A01 Typhoid and paratyphoid fevers	0.621	0.378
A00 Cholera	0.621	0.378
K65-K67 Diseases of peritoneum	0.621	0.379
S70.0 Contusion of hip	0.621	0.379
G61.9 Inflammatory polyneuropathy, unspecified	0.620	0.380
G61.1 Serum neuropathy	0.620	0.380
W25 Contact with sharp glass	0.620	0.380
H61.2 Impacted cerumen	0.620	0.380
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.619	0.381
O30.0 Twin pregnancy	0.619	0.381
G41.9 Status epilepticus, unspecified	0.619	0.381
O21.9 Vomiting of pregnancy, unspecified	0.619	0.381
G46 Vascular syndromes of brain in cerebrovascular diseases	0.619	0.381
S64 Injury of nerves at wrist and hand level	0.618	0.382
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.618	0.382
A63.0 Anogenital (venereal) warts	0.618	0.382
Q61.3 Polycystic kidney, unspecified	0.617	0.383
S79 Other and unspecified injuries of hip and thigh	0.617	0.383
E04.2 Non-toxic multinodular goitre	0.617	0.383
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.617	0.383
Y52.8 Antivaricose drugs, including sclerosing agents	0.617	0.383

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations