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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78798473
log Bayes Factor = 19.9784
Chromosome 4   position 1,669,252  (GRCh37) Explore rs78798473 on Ensembl!
Variant rs78798473 is part of Cluster X0024

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
D64.9 Anaemia, unspecified
1.000 0.000 0.000
D64 Other anaemias
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
I50 Heart failure
0.996 0.004 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.994 0.006 0.000
I35 Nonrheumatic aortic valve disorders
0.993 0.007 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.993 0.007 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.991 0.009 0.000
I35.0 Aortic (valve) stenosis
0.989 0.011 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.988 0.012 0.000
I50.1 Left ventricular failure
0.988 0.012 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.987 0.013 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.985 0.015 0.000
I05-I09 Chronic rheumatic heart diseases
0.981 0.019 0.000
M45-M49 Spondylopathies
0.980 0.020 0.000
Chapter V Mental and behavioural disorders
0.979 0.021 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.974 0.026 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.971 0.029 0.000
I10-I15 Hypertensive diseases
0.966 0.034 0.000
M47 Spondylosis
0.962 0.038 0.000
Chapter II Neoplasms
0.960 0.040 0.000
Chapter I Certain infectious and parasitic diseases
0.958 0.042 0.000
K83 Other diseases of biliary tract
0.957 0.043 0.000
K70-K77 Diseases of liver
0.952 0.048 0.000
O26.8 Other specified pregnancy-related conditions
0.948 0.052 0.000
K80 Cholelithiasis
0.946 0.054 0.000
I08 Multiple valve diseases
0.945 0.055 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.943 0.057 0.000
E86 Volume depletion
0.942 0.058 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.941 0.059 0.000
E78.5 Hyperlipidaemia, unspecified
0.940 0.060 0.000
K83.8 Other specified diseases of biliary tract
0.935 0.065 0.000
K14 Diseases of tongue
0.933 0.067 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.932 0.068 0.000
I50.0 Congestive heart failure
0.931 0.069 0.000
I10 Essential (primary) hypertension
0.928 0.072 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.926 0.074 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.917 0.083 0.000
M47.8 Other spondylosis
0.916 0.084 0.000
T66-T78 Other and unspecified effects of external causes
0.916 0.084 0.000
O42 Premature rupture of membranes
0.913 0.087 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.912 0.088 0.000
Chapter XXI Factors influencing health status and contact with health services
0.911 0.089 0.000
I44 Atrioventricular and left bundle-branch block
0.911 0.089 0.000
M48 Other spondylopathies
0.911 0.089 0.000
K02 Dental caries
0.910 0.090 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.909 0.091 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.906 0.094 0.000
C79 Secondary malignant neoplasm of other sites
0.905 0.095 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.905 0.095 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.904 0.096 0.000
C51-C58 Malignant neoplasms of female genital organs
0.902 0.098 0.000
I31 Other diseases of pericardium
0.897 0.103 0.000
I77 Other disorders of arteries and arterioles
0.896 0.104 0.000
K76 Other diseases of liver
0.895 0.105 0.000
K04 Diseases of pulp and periapical tissues
0.893 0.107 0.000
D50-D53 Nutritional anaemias
0.893 0.107 0.000
M47.82 Other spondylosis (Cervical region)
0.893 0.107 0.000
Z80 Family history of malignant neoplasm
0.891 0.109 0.000
O26.9 Pregnancy-related condition, unspecified
0.889 0.111 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.888 0.112 0.000
Chapter VII Diseases of the eye and adnexa
0.885 0.115 0.000
K85 Acute pancreatitis
0.884 0.116 0.000
M47.9 Spondylosis, unspecified
0.882 0.118 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.882 0.118 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.873 0.127 0.000
C50-C50 Malignant neoplasm of breast
0.870 0.130 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.870 0.130 0.000
M86-M90 Other osteopathies
0.869 0.131 0.000
K11 Diseases of salivary glands
0.868 0.132 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.863 0.137 0.000
E83 Disorders of mineral metabolism
0.862 0.138 0.000
O60-O75 Complications of labour and delivery
0.862 0.138 0.000
B95-B98 Bacterial, viral and other infectious agents
0.859 0.141 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.859 0.141 0.000
Z90.7 Acquired absence of genital organ(s)
0.858 0.142 0.000
M48.0 Spinal stenosis
0.854 0.146 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.854 0.146 0.000
I37 Pulmonary valve disorders
0.854 0.146 0.000
A30-A49 Other bacterial diseases
0.853 0.147 0.000
O42.9 Premature rupture of membranes, unspecified
0.853 0.147 0.000
K14.8 Other diseases of tongue
0.852 0.148 0.000
C56 Malignant neoplasm of ovary
0.851 0.149 0.000
S20-S29 Injuries to the thorax
0.850 0.150 0.000
F41 Other anxiety disorders
0.848 0.152 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.847 0.153 0.000
K90-K93 Other diseases of the digestive system
0.846 0.154 0.000
K04.5 Chronic apical periodontitis
0.843 0.157 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.840 0.160 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.840 0.160 0.000
T78 Adverse effects, not elsewhere classified
0.839 0.161 0.000
E78.1 Pure hyperglyceridaemia
0.838 0.162 0.000
E20-E35 Disorders of other endocrine glands
0.837 0.163 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.836 0.164 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.836 0.164 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.835 0.165 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.834 0.166 0.000
S50-S59 Injuries to the elbow and forearm
0.833 0.167 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.828 0.172 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.827 0.173 0.000
E50-E64 Other nutritional deficiencies
0.822 0.178 0.000
K02.9 Dental caries, unspecified
0.820 0.180 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.820 0.180 0.000
M40-M43 Deforming dorsopathies
0.820 0.180 0.000
I44.0 Atrioventricular block, first degree
0.820 0.180 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.817 0.183 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.817 0.183 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.816 0.184 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.814 0.186 0.000
B35-B49 Mycoses
0.813 0.187 0.000
M70-M79 Other soft tissue disorders
0.813 0.187 0.000
I05 Rheumatic mitral valve diseases
0.813 0.187 0.000
D61 Other aplastic anaemias
0.812 0.188 0.000
K80.8 Other cholelithiasis
0.811 0.189 0.000
F03 Unspecified dementia
0.810 0.190 0.000
Z88.2 Personal history of allergy to sulphonamides
0.808 0.192 0.000
I77.1 Stricture of artery
0.808 0.192 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.808 0.192 0.000
F00 Dementia in Alzheimer's disease
0.807 0.193 0.000
K74 Fibrosis and cirrhosis of liver
0.806 0.194 0.000
T79-T79 Certain early complications of trauma
0.806 0.194 0.000
I72 Other aneurysm
0.806 0.194 0.000
Z80.3 Family history of malignant neoplasm of breast
0.805 0.195 0.000
C50 Malignant neoplasm of breast
0.805 0.195 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.805 0.195 0.000
I07 Rheumatic tricuspid valve diseases
0.802 0.197 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.798 0.202 0.000
K76.8 Other specified diseases of liver
0.796 0.204 0.000
D50 Iron deficiency anaemia
0.795 0.205 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.794 0.206 0.000
I31.9 Disease of pericardium, unspecified
0.791 0.209 0.000
I44.1 Atrioventricular block, second degree
0.791 0.209 0.000
M48.02 Spinal stenosis (Cervical region)
0.790 0.210 0.000
Chapter XXII Codes for special purposes
0.788 0.212 0.000
I35.9 Aortic valve disorder, unspecified
0.787 0.212 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.786 0.214 0.000
I95 Hypotension
0.786 0.214 0.000
F43 Reaction to severe stress, and adjustment disorders
0.786 0.214 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.786 0.214 0.000
Z87 Personal history of other diseases and conditions
0.784 0.216 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.782 0.218 0.000
S32 Fracture of lumbar spine and pelvis
0.782 0.218 0.000
E74 Other disorders of carbohydrate metabolism
0.781 0.219 0.000
D62 Acute posthaemorrhagic anaemia
0.779 0.220 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.775 0.225 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.773 0.227 0.000
I33 Acute and subacute endocarditis
0.773 0.227 0.000
S40-S49 Injuries to the shoulder and upper arm
0.773 0.227 0.000
O40 Polyhydramnios
0.771 0.229 0.000
D00-D09 In situ neoplasms
0.770 0.230 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.770 0.230 0.000
K09 Cysts of oral region, not elsewhere classified
0.769 0.231 0.000
K81 Cholecystitis
0.768 0.232 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.768 0.232 0.000
I36 Nonrheumatic tricuspid valve disorders
0.767 0.232 0.000
I11 Hypertensive heart disease
0.766 0.234 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.765 0.235 0.000
S10-S19 Injuries to the neck
0.763 0.237 0.000
K11.5 Sialolithiasis
0.763 0.237 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.762 0.238 0.000
E65-E68 Obesity and other hyperalimentation
0.761 0.239 0.000
O85-O92 Complications predominantly related to the puerperium
0.761 0.239 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.761 0.239 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.760 0.240 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.760 0.240 0.000
I74 Arterial embolism and thrombosis
0.760 0.240 0.000
K35-K38 Diseases of appendix
0.758 0.242 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.756 0.244 0.000
E83.4 Disorders of magnesium metabolism
0.756 0.244 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.756 0.244 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.755 0.245 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.755 0.245 0.000
K85.1 Biliary acute pancreatitis
0.755 0.245 0.000
E78.8 Other disorders of lipoprotein metabolism
0.754 0.246 0.000
Z91.6 Personal history of other physical trauma
0.753 0.247 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.752 0.248 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.752 0.248 0.000
Chapter XX External causes of morbidity and mortality
0.752 0.248 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.751 0.249 0.000
S90-S99 Injuries to the ankle and foot
0.751 0.249 0.000
O23 Infections of genito-urinary tract in pregnancy
0.750 0.249 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.750 0.250 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.750 0.250 0.000
I37.1 Pulmonary valve insufficiency
0.750 0.250 0.000
O30 Multiple gestation
0.749 0.251 0.000
F41.2 Mixed anxiety and depressive disorder
0.749 0.251 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.749 0.251 0.000
M89 Other disorders of bone
0.748 0.252 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.748 0.252 0.000
K82 Other diseases of gallbladder
0.747 0.253 0.000
O43 Placental disorders
0.747 0.253 0.000
M47.1 Other spondylosis with myelopathy
0.746 0.254 0.000
K14.9 Disease of tongue, unspecified
0.745 0.254 0.000
O34.1 Maternal care for tumour of corpus uteri
0.745 0.255 0.000
Chapter VIII Diseases of the ear and mastoid process
0.744 0.256 0.000
K02.8 Other dental caries
0.743 0.257 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.742 0.258 0.000
K14.0 Glossitis
0.742 0.258 0.000
I95.9 Hypotension, unspecified
0.742 0.258 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.741 0.259 0.000
E00-E07 Disorders of thyroid gland
0.740 0.260 0.000
H10-H13 Disorders of conjunctiva
0.740 0.260 0.000
H02 Other disorders of eyelid
0.740 0.260 0.000
K10 Other diseases of jaws
0.740 0.260 0.000
O21 Excessive vomiting in pregnancy
0.740 0.260 0.000
D75 Other diseases of blood and blood-forming organs
0.739 0.261 0.000
I35.1 Aortic (valve) insufficiency
0.739 0.261 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.738 0.262 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.737 0.263 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.735 0.264 0.000
S00-S09 Injuries to the head
0.735 0.265 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.734 0.266 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.733 0.267 0.000
I12 Hypertensive renal disease
0.733 0.267 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.732 0.268 0.000
I30 Acute pericarditis
0.732 0.268 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.731 0.268 0.000
T68 Hypothermia
0.731 0.269 0.000
K85.9 Acute pancreatitis, unspecified
0.730 0.270 0.000
I44.2 Atrioventricular block, complete
0.730 0.270 0.000
K01 Embedded and impacted teeth
0.730 0.270 0.000
K12 Stomatitis and related lesions
0.729 0.271 0.000
M00-M03 Infectious arthropathies
0.728 0.272 0.000
K00 Disorders of tooth development and eruption
0.728 0.272 0.000
I42 Cardiomyopathy
0.728 0.272 0.000
S51 Open wound of forearm
0.727 0.273 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.727 0.273 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.726 0.274 0.000
O41 Other disorders of amniotic fluid and membranes
0.726 0.274 0.000
A00-A09 Intestinal infectious diseases
0.725 0.275 0.000
I77.8 Other specified disorders of arteries and arterioles
0.724 0.276 0.000
S27 Injury of other and unspecified intrathoracic organs
0.724 0.276 0.000
E83.3 Disorders of phosphorus metabolism
0.724 0.276 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.723 0.277 0.000
O36 Maternal care for other known or suspected foetal problems
0.723 0.277 0.000
C79.2 Secondary malignant neoplasm of skin
0.721 0.279 0.000
I31.3 Pericardial effusion (noninflammatory)
0.720 0.280 0.000
M91-M94 Chondropathies
0.719 0.281 0.000
H55-H59 Other disorders of eye and adnexa
0.718 0.282 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.718 0.282 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.717 0.282 0.000
Z87.8 Personal history of other specified conditions
0.717 0.283 0.000
C50.1 Central portion of breast
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
D55-D59 Haemolytic anaemias
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
D64.8 Other specified anaemias
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
E80.4 Gilbert's syndrome
0.716 0.284 0.000
E85 Amyloidosis
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E73 Lactose intolerance
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
C78.0 Secondary malignant neoplasm of lung
0.715 0.285 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.715 0.285 0.000
M20-M25 Other joint disorders
0.715 0.285 0.000
A49 Bacterial infection of unspecified site
0.714 0.286 0.000
F60-F69 Disorders of adult personality and behaviour
0.714 0.286 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.713 0.287 0.000
I35.8 Other aortic valve disorders
0.712 0.288 0.000
T33-T35 Frostbite
0.712 0.288 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.288 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.712 0.288 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.288 0.000
K03 Other diseases of hard tissues of teeth
0.710 0.289 0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge
0.710 0.290 0.000
F99-F99 Unspecified mental disorder
0.710 0.290 0.000
O71 Other obstetric trauma
0.710 0.290 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.709 0.291 0.000
D53 Other nutritional anaemias
0.709 0.291 0.000
O45 Premature separation of placenta [abruptio placentae]
0.709 0.291 0.000
O44 Placenta praevia
0.709 0.291 0.000
O33 Maternal care for known or suspected disproportion
0.709 0.291 0.000
O31 Complications specific to multiple gestation
0.709 0.291 0.000
I72.4 Aneurysm of artery of lower extremity
0.708 0.292 0.000
M60-M63 Disorders of muscles
0.708 0.292 0.000
K65-K67 Diseases of peritoneum
0.708 0.292 0.000
Z89 Acquired absence of limb
0.708 0.292 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.707 0.293 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.707 0.293 0.000
O29 Complications of anaesthesia during pregnancy
0.706 0.293 0.000
O28 Abnormal findings on antenatal screening of mother
0.706 0.293 0.000
O24 Diabetes mellitus in pregnancy
0.706 0.293 0.000
O22 Venous complications in pregnancy
0.706 0.293 0.000
O25 Malnutrition in pregnancy
0.706 0.293 0.000
E28 Ovarian dysfunction
0.705 0.295 0.000
H02.4 Ptosis of eyelid
0.704 0.296 0.000
I09 Other rheumatic heart diseases
0.703 0.297 0.000
I06 Rheumatic aortic valve diseases
0.703 0.297 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.703 0.297 0.000
F42 Obsessive-compulsive disorder
0.703 0.297 0.000
M49 Spondylopathies in diseases classified elsewhere
0.703 0.297 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.703 0.297 0.000
K75 Other inflammatory liver diseases
0.702 0.298 0.000
T78.2 Anaphylactic shock, unspecified
0.702 0.298 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.702 0.298 0.000
F70-F79 Mental retardation
0.702 0.298 0.000
Z91.5 Personal history of self-harm
0.702 0.298 0.000
H04 Disorders of lachrymal system
0.702 0.298 0.000
A80-A89 Viral infections of the central nervous system
0.700 0.299 0.000
I27 Other pulmonary heart diseases
0.699 0.301 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.698 0.302 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.698 0.302 0.000
O26.5 Maternal hypotension syndrome
0.698 0.302 0.000
O26.4 Herpes gestationis
0.698 0.302 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.698 0.302 0.000
O26.2 Pregnancy care of habitual aborter
0.698 0.302 0.000
O26.1 Low weight gain in pregnancy
0.698 0.302 0.000
O26.0 Excessive weight gain in pregnancy
0.698 0.302 0.000
Z90.1 Acquired absence of breast(s)
0.698 0.302 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.698 0.302 0.000
D80-D89 Certain disorders involving the immune mechanism
0.697 0.302 0.000
E83.1 Disorders of iron metabolism
0.697 0.303 0.000
E78.6 Lipoprotein deficiency
0.696 0.304 0.000
E78.4 Other hyperlipidaemia
0.696 0.304 0.000
E78.3 Hyperchylomicronaemia
0.696 0.304 0.000
E40-E46 Malnutrition
0.696 0.304 0.000
E78.2 Mixed hyperlipidaemia
0.695 0.304 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.695 0.305 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.695 0.305 0.000
I15 Secondary hypertension
0.693 0.307 0.000
I13 Hypertensive heart and renal disease
0.693 0.307 0.000
F80-F89 Disorders of psychological development
0.693 0.307 0.000
D03 Melanoma in situ
0.692 0.308 0.000
K83.1 Obstruction of bile duct
0.691 0.309 0.000
H60-H62 Diseases of external ear
0.691 0.309 0.000
D68 Other coagulation defects
0.690 0.310 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.690 0.310 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.690 0.310 0.000
F30-F39 Mood [affective] disorders
0.690 0.310 0.000
A41 Other septicaemia
0.689 0.311 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.688 0.312 0.000
H53-H54 Visual disturbances and blindness
0.688 0.312 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.688 0.312 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.688 0.312 0.000
I51 Complications and ill-defined descriptions of heart disease
0.688 0.312 0.000
C51 Malignant neoplasm of vulva
0.688 0.312 0.000
Z90.8 Acquired absence of other organs
0.688 0.312 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.687 0.312 0.000
E03 Other hypothyroidism
0.687 0.312 0.000
B99-B99 Other infectious diseases
0.687 0.313 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.687 0.313 0.000
B65-B83 Helminthiases
0.687 0.313 0.000
B50-B64 Protozoal diseases
0.687 0.313 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.687 0.313 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.687 0.313 0.000
A75-A79 Rickettsioses
0.687 0.313 0.000
A70-A74 Other diseases caused by chlamydiae
0.687 0.313 0.000
A65-A69 Other spirochaetal diseases
0.687 0.313 0.000
A20-A28 Certain zoonotic bacterial diseases
0.687 0.313 0.000
A15-A19 Tuberculosis
0.687 0.313 0.000
K83.9 Disease of biliary tract, unspecified
0.686 0.314 0.000
K83.5 Biliary cyst
0.686 0.314 0.000
K83.4 Spasm of sphincter of Oddi
0.686 0.314 0.000
K83.3 Fistula of bile duct
0.686 0.314 0.000
K83.2 Perforation of bile duct
0.686 0.314 0.000
O47 False labour
0.686 0.314 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.685 0.315 0.000
C54 Malignant neoplasm of corpus uteri
0.684 0.316 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.684 0.316 0.000
O00-O08 Pregnancy with abortive outcome
0.683 0.317 0.000
M45 Ankylosing spondylitis
0.683 0.317 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.682 0.317 0.000
Z84 Family history of other conditions
0.682 0.317 0.000
K77 Liver disorders in diseases classified elsewhere
0.682 0.318 0.000
K73 Chronic hepatitis, not elsewhere classified
0.682 0.318 0.000
K71 Toxic liver disease
0.682 0.318 0.000
B44 Aspergillosis
0.682 0.318 0.000
I05.9 Mitral valve disease, unspecified
0.682 0.318 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.682 0.318 0.000
S70-S79 Injuries to the hip and thigh
0.682 0.318 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.681 0.319 0.000
M79.6 Pain in limb
0.681 0.319 0.000
M86 Osteomyelitis
0.679 0.321 0.000
K80.3 Calculus of bile duct with cholangitis
0.679 0.321 0.000
I08.9 Multiple valve disease, unspecified
0.678 0.322 0.000
I08.8 Other multiple valve diseases
0.678 0.322 0.000
D61.9 Aplastic anaemia, unspecified
0.677 0.323 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.676 0.324 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.675 0.325 0.000
M46 Other inflammatory spondylopathies
0.675 0.325 0.000
I07.1 Tricuspid insufficiency
0.675 0.325 0.000
D72 Other disorders of white blood cells
0.674 0.326 0.000
I38 Endocarditis, valve unspecified
0.674 0.326 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.671 0.329 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.671 0.329 0.000
M65-M68 Disorders of synovium and tendon
0.671 0.329 0.000
K72 Hepatic failure, not elsewhere classified
0.671 0.329 0.000
O32.1 Maternal care for breech presentation
0.671 0.329 0.000
O66 Other obstructed labour
0.670 0.330 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.670 0.330 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.669 0.330 0.000
Z88.6 Personal history of allergy to analgesic agent
0.670 0.330 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.669 0.330 0.000
K14.6 Glossodynia
0.669 0.331 0.000
K14.5 Plicated tongue
0.669 0.331 0.000
K14.4 Atrophy of tongue papillae
0.669 0.331 0.000
K14.3 Hypertrophy of tongue papillae
0.669 0.331 0.000
K14.2 Median rhomboid glossitis
0.669 0.331 0.000
K14.1 Geographic tongue
0.669 0.331 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.668 0.332 0.000
F02 Dementia in other diseases classified elsewhere
0.668 0.332 0.000
F09 Unspecified organic or symptomatic mental disorder
0.668 0.332 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.668 0.332 0.000
E87.2 Acidosis
0.668 0.332 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.667 0.333 0.000
F45 Somatoform disorders
0.665 0.335 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.665 0.335 0.000
F48 Other neurotic disorders
0.664 0.336 0.000
F44 Dissociative [conversion] disorders
0.664 0.336 0.000
M41 Scoliosis
0.664 0.336 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.664 0.336 0.000
D50.8 Other iron deficiency anaemias
0.663 0.337 0.000
A40 Streptococcal septicaemia
0.663 0.337 0.000
S80-S89 Injuries to the knee and lower leg
0.662 0.338 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.662 0.338 0.000
T78.3 Angioneurotic oedema
0.662 0.338 0.000
E88 Other metabolic disorders
0.662 0.338 0.000
K04.6 Periapical abscess with sinus
0.662 0.338 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.660 0.340 0.000
E87.0 Hyperosmolality and hypernatraemia
0.660 0.340 0.000
E22 Hyperfunction of pituitary gland
0.658 0.342 0.000
F01 Vascular dementia
0.658 0.342 0.000
K04.7 Periapical abscess without sinus
0.658 0.342 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.658 0.342 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.657 0.342 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.657 0.342 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.657 0.342 0.000
O34.6 Maternal care for abnormality of vagina
0.657 0.342 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.657 0.342 0.000
O34.4 Maternal care for other abnormalities of cervix
0.657 0.342 0.000
O34.3 Maternal care for cervical incompetence
0.657 0.342 0.000
O34.0 Maternal care for congenital malformation of uterus
0.657 0.342 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.657 0.343 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.657 0.343 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.657 0.343 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.657 0.343 0.000
M47.84 Other spondylosis (Thoracic region)
0.657 0.343 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.657 0.343 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.657 0.343 0.000
T75 Effects of other external causes
0.657 0.343 0.000
T74 Maltreatment syndromes
0.657 0.343 0.000
T73 Effects of other deprivation
0.657 0.343 0.000
T70 Effects of air pressure and water pressure
0.657 0.343 0.000
T69 Other effects of reduced temperature
0.657 0.343 0.000
T67 Effects of heat and light
0.657 0.343 0.000
T71 Asphyxiation
0.657 0.343 0.000
T66 Unspecified effects of radiation
0.657 0.343 0.000
I77.6 Arteritis, unspecified
0.657 0.343 0.000
K90 Intestinal malabsorption
0.656 0.344 0.000
D50.9 Iron deficiency anaemia, unspecified
0.656 0.344 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.655 0.345 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.655 0.345 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.655 0.345 0.000
Z81 Family history of mental and behavioural disorders
0.654 0.346 0.000
O20 Haemorrhage in early pregnancy
0.654 0.346 0.000
C50.5 Lower-outer quadrant of breast
0.654 0.346 0.000
Chapter VI Diseases of the nervous system
0.653 0.347 0.000
I44.6 Other and unspecified fascicular block
0.653 0.347 0.000
I44.5 Left posterior fascicular block
0.653 0.347 0.000
I44.4 Left anterior fascicular block
0.653 0.347 0.000
I44.3 Other and unspecified atrioventricular block
0.653 0.347 0.000
M48.9 Spondylopathy, unspecified
0.653 0.347 0.000
M48.8 Other specified spondylopathies
0.653 0.347 0.000
M48.4 Fatigue fracture of vertebra
0.653 0.347 0.000
M48.3 Traumatic spondylopathy
0.653 0.347 0.000
M48.2 Kissing spine
0.653 0.347 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.653 0.347 0.000
K02.5 Caries with pulp exposure
0.652 0.348 0.000
K02.4 Odontoclasia
0.652 0.348 0.000
K02.3 Arrested dental caries
0.652 0.348 0.000
K02.2 Caries of cementum
0.652 0.348 0.000
K02.1 Caries of dentin
0.652 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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