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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78835444
log Bayes Factor = 6.92131
Chromosome 4   position 111,317,679  (GRCh37) Explore rs78835444 on Ensembl!
Variant rs78835444 is part of Cluster X0263

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
M54 Dorsalgia
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
0.999 0.001 0.000
M45-M49 Spondylopathies
0.998 0.002 0.000
M47 Spondylosis
0.993 0.007 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.993 0.007 0.000
M54.3 Sciatica
0.991 0.009 0.000
M54.5 Low back pain
0.983 0.017 0.000
H65-H75 Diseases of middle ear and mastoid
0.981 0.019 0.000
M54.39 Sciatica (Site unspecified)
0.979 0.021 0.000
M54.9 Dorsalgia, unspecified
0.972 0.028 0.000
H60-H62 Diseases of external ear
0.970 0.030 0.000
M54.59 Low back pain (Site unspecified)
0.968 0.032 0.000
H72 Perforation of tympanic membrane
0.968 0.032 0.000
M47.8 Other spondylosis
0.963 0.037 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.963 0.037 0.000
S80-S89 Injuries to the knee and lower leg
0.957 0.043 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.956 0.044 0.000
H60 Otitis externa
0.956 0.044 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.956 0.044 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.955 0.045 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.955 0.045 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.949 0.051 0.000
Chapter VII Diseases of the eye and adnexa
0.930 0.070 0.000
C18 Malignant neoplasm of colon
0.929 0.071 0.000
C15-C26 Malignant neoplasms of digestive organs
0.928 0.072 0.000
Chapter II Neoplasms
0.928 0.072 0.000
H90-H95 Other disorders of ear
0.923 0.077 0.000
H30-H36 Disorders of choroid and retina
0.922 0.078 0.000
M47.9 Spondylosis, unspecified
0.916 0.084 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.916 0.084 0.000
S82 Fracture of lower leg, including ankle
0.915 0.085 0.000
M47.86 Other spondylosis (Lumbar region)
0.913 0.087 0.000
C18.9 Colon, unspecified
0.909 0.091 0.000
H33 Retinal detachments and breaks
0.907 0.093 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.907 0.093 0.000
T66-T78 Other and unspecified effects of external causes
0.907 0.093 0.000
C18.0 Caecum
0.905 0.095 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.902 0.098 0.000
H90 Conductive and sensorineural hearing loss
0.898 0.102 0.000
H60.9 Otitis externa, unspecified
0.896 0.104 0.000
E20-E35 Disorders of other endocrine glands
0.893 0.107 0.000
S50-S59 Injuries to the elbow and forearm
0.890 0.110 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.888 0.112 0.000
M47.2 Other spondylosis with radiculopathy
0.887 0.113 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.884 0.116 0.000
S10-S19 Injuries to the neck
0.881 0.119 0.000
M86-M90 Other osteopathies
0.879 0.121 0.000
M51 Other intervertebral disk disorders
0.876 0.124 0.000
M54.36 Sciatica (Lumbar region)
0.872 0.128 0.000
H35 Other retinal disorders
0.866 0.134 0.000
M46 Other inflammatory spondylopathies
0.865 0.135 0.000
D00-D09 In situ neoplasms
0.861 0.139 0.000
S82.2 Fracture of shaft of tibia
0.861 0.139 0.000
C20 Malignant neoplasm of rectum
0.860 0.140 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.859 0.141 0.000
T78 Adverse effects, not elsewhere classified
0.859 0.141 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.859 0.141 0.000
H60.3 Other infective otitis externa
0.859 0.141 0.000
H33.0 Retinal detachment with retinal break
0.857 0.143 0.000
C18.6 Descending colon
0.857 0.143 0.000
H90.2 Conductive hearing loss, unspecified
0.855 0.145 0.000
H33.3 Retinal breaks without detachment
0.854 0.146 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.849 0.151 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.848 0.152 0.000
S90-S99 Injuries to the ankle and foot
0.846 0.154 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.844 0.156 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.843 0.157 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.841 0.159 0.000
H66 Suppurative and unspecified otitis media
0.839 0.161 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.838 0.162 0.000
M70-M79 Other soft tissue disorders
0.836 0.164 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.835 0.165 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.834 0.166 0.000
Chapter XX External causes of morbidity and mortality
0.831 0.169 0.000
H18 Other disorders of cornea
0.828 0.172 0.000
T85.2 Mechanical complication of intraocular lens
0.828 0.172 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.827 0.173 0.000
T88.4 Failed or difficult intubation
0.826 0.174 0.000
T79-T79 Certain early complications of trauma
0.823 0.177 0.000
S52 Fracture of forearm
0.820 0.180 0.000
M51.8 Other specified intervertebral disk disorders
0.819 0.181 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.817 0.183 0.000
S82.6 Fracture of lateral malleolus
0.815 0.185 0.000
S70-S79 Injuries to the hip and thigh
0.813 0.187 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.813 0.187 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.813 0.187 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.812 0.188 0.000
H35.8 Other specified retinal disorders
0.809 0.191 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.806 0.194 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.805 0.195 0.000
S32 Fracture of lumbar spine and pelvis
0.803 0.197 0.000
M45 Ankylosing spondylitis
0.802 0.197 0.000
E10-E14 Diabetes mellitus
0.798 0.202 0.000
M47.84 Other spondylosis (Thoracic region)
0.796 0.204 0.000
H72.0 Central perforation of tympanic membrane
0.793 0.207 0.000
T87 Complications peculiar to reattachment and amputation
0.792 0.208 0.000
Q00-Q07 Congenital malformations of the nervous system
0.792 0.208 0.000
S81 Open wound of lower leg
0.790 0.210 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.789 0.211 0.000
M40-M43 Deforming dorsopathies
0.789 0.211 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.788 0.212 0.000
M54.50 Low back pain (Multiple sites in spine)
0.787 0.213 0.000
H16 Keratitis
0.786 0.214 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.785 0.215 0.000
T20 Burn and corrosion of head and neck
0.783 0.217 0.000
C51-C58 Malignant neoplasms of female genital organs
0.782 0.218 0.000
M86 Osteomyelitis
0.782 0.218 0.000
M54.57 Low back pain (Lumbosacral region)
0.782 0.218 0.000
M49 Spondylopathies in diseases classified elsewhere
0.782 0.218 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.781 0.219 0.000
S31 Open wound of abdomen, lower back and pelvis
0.779 0.221 0.000
S12 Fracture of neck
0.777 0.223 0.000
S82.21 Fracture of shaft of tibia (open)
0.773 0.227 0.000
T78.2 Anaphylactic shock, unspecified
0.771 0.229 0.000
H60.5 Acute otitis externa, non-infective
0.769 0.231 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.769 0.231 0.000
M80-M85 Disorders of bone density and structure
0.769 0.231 0.000
E21.3 Hyperparathyroidism, unspecified
0.769 0.231 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.769 0.231 0.000
M60-M63 Disorders of muscles
0.767 0.233 0.000
H60.1 Cellulitis of external ear
0.767 0.233 0.000
H66.9 Otitis media, unspecified
0.763 0.237 0.000
M91-M94 Chondropathies
0.759 0.241 0.000
M48 Other spondylopathies
0.758 0.242 0.000
S82.20 Fracture of shaft of tibia (closed)
0.755 0.245 0.000
H74 Other disorders of middle ear and mastoid
0.755 0.245 0.000
C23 Malignant neoplasm of gallbladder
0.754 0.246 0.000
C17 Malignant neoplasm of small intestine
0.754 0.246 0.000
S82.0 Fracture of patella
0.751 0.249 0.000
Q80-Q89 Other congenital malformations
0.750 0.250 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.750 0.250 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.747 0.253 0.000
E28 Ovarian dysfunction
0.747 0.253 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.747 0.253 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.746 0.254 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.745 0.255 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.744 0.255 0.000
E34 Other endocrine disorders
0.744 0.256 0.000
S82.60 Fracture of lateral malleolus (closed)
0.744 0.256 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.743 0.257 0.000
S52.0 Fracture of upper end of ulna
0.741 0.259 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.739 0.261 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.737 0.263 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.736 0.264 0.000
H18.9 Disorder of cornea, unspecified
0.735 0.265 0.000
M54.55 Low back pain (Thoracolumbar region)
0.735 0.265 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.730 0.270 0.000
D09 Carcinoma in situ of other and unspecified sites
0.730 0.270 0.000
E29 Testicular dysfunction
0.729 0.271 0.000
S80 Superficial injury of lower leg
0.729 0.271 0.000
S90 Superficial injury of ankle and foot
0.729 0.271 0.000
W20-W49 Exposure to inanimate mechanical forces
0.729 0.271 0.000
S52.1 Fracture of upper end of radius
0.728 0.272 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.728 0.272 0.000
H35.4 Peripheral retinal degeneration
0.727 0.273 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.727 0.273 0.000
S20-S29 Injuries to the thorax
0.726 0.273 0.000
W00-W19 Falls
0.726 0.274 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.726 0.274 0.000
Q50-Q56 Congenital malformations of genital organs
0.725 0.275 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.724 0.276 0.000
C18.7 Sigmoid colon
0.723 0.277 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.722 0.278 0.000
M54.1 Radiculopathy
0.722 0.278 0.000
T21 Burn and corrosion of trunk
0.721 0.279 0.000
D06 Carcinoma in situ of cervix uteri
0.720 0.280 0.000
T14 Injury of unspecified body region
0.720 0.280 0.000
M53 Other dorsopathies, not elsewhere classified
0.720 0.280 0.000
S14 Injury of nerves and spinal cord at neck level
0.720 0.280 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M54.8 Other dorsalgia
0.717 0.283 0.000
M54.0 Panniculitis affecting regions of neck and back
0.717 0.283 0.000
M79.0 Rheumatism, unspecified
0.712 0.288 0.000
S82.7 Multiple fractures of lower leg
0.712 0.288 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.712 0.288 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.711 0.289 0.000
M54.35 Sciatica (Thoracolumbar region)
0.711 0.289 0.000
M54.34 Sciatica-Thoracic
0.711 0.289 0.000
M54.33 Sciatica-Cervicothoracic
0.711 0.289 0.000
M54.32 Sciatica-Cervical
0.711 0.289 0.000
M54.31 Sciatica-Occipit-atl-axl
0.711 0.289 0.000
M54.30 Sciatica (Multiple sites in spine)
0.711 0.289 0.000
M00-M03 Infectious arthropathies
0.708 0.291 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.708 0.292 0.000
C18.4 Transverse colon
0.708 0.292 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.707 0.293 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.705 0.295 0.000
M54.54 Low back pain-Thoracic
0.705 0.295 0.000
M54.53 Low back pain-Cervicothoracic
0.705 0.295 0.000
M54.52 Low back pain-Cervical
0.705 0.295 0.000
M54.51 Low back pain-Occipit-atl-axl
0.705 0.295 0.000
T23 Burn and corrosion of wrist and hand
0.704 0.296 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.704 0.296 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.703 0.296 0.000
H70 Mastoiditis and related conditions
0.703 0.296 0.000
H68 Eustachian salpingitis and obstruction
0.703 0.296 0.000
H67 Otitis media in diseases classified elsewhere
0.703 0.296 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.702 0.298 0.000
M86.9 Osteomyelitis, unspecified
0.701 0.299 0.000
E14 Unspecified diabetes mellitus
0.698 0.302 0.000
H33.5 Other retinal detachments
0.698 0.302 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.698 0.302 0.000
M84 Disorders of continuity of bone
0.698 0.302 0.000
H18.6 Keratoconus
0.698 0.302 0.000
D05 Carcinoma in situ of breast
0.697 0.302 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.697 0.303 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.697 0.303 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.697 0.303 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.697 0.303 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.697 0.303 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.697 0.303 0.000
M89 Other disorders of bone
0.697 0.303 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.696 0.303 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.695 0.304 0.000
S86 Injury of muscle and tendon at lower leg level
0.694 0.305 0.000
H72.2 Other marginal perforations of tympanic membrane
0.694 0.306 0.000
H72.1 Attic perforation of tympanic membrane
0.694 0.306 0.000
E23 Hypofunction and other disorders of pituitary gland
0.691 0.309 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.691 0.309 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.691 0.309 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.691 0.309 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.691 0.309 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.691 0.309 0.000
Q35-Q37 Cleft lip and cleft palate
0.691 0.309 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.691 0.309 0.000
T90 Sequelae of injuries of head
0.689 0.311 0.000
M54.37 Sciatica (Lumbosacral region)
0.688 0.312 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.687 0.313 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.686 0.314 0.000
S88 Traumatic amputation of lower leg
0.686 0.314 0.000
S87 Crushing injury of lower leg
0.686 0.314 0.000
S85 Injury of blood vessels at lower leg level
0.686 0.314 0.000
S84 Injury of nerves at lower leg level
0.686 0.314 0.000
H31 Other disorders of choroid
0.686 0.314 0.000
H60.8 Other otitis externa
0.685 0.315 0.000
H60.4 Cholesteatoma of external ear
0.685 0.315 0.000
H60.2 Malignant otitis externa
0.685 0.315 0.000
H60.0 Abscess of external ear
0.685 0.315 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.685 0.315 0.000
M51.9 Intervertebral disk disorder, unspecified
0.685 0.315 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.685 0.315 0.000
E21.0 Primary hyperparathyroidism
0.685 0.315 0.000
Q24 Other congenital malformations of heart
0.684 0.316 0.000
H35.6 Retinal haemorrhage
0.684 0.316 0.000
E24 Cushing's syndrome
0.684 0.316 0.000
H71 Cholesteatoma of middle ear
0.684 0.316 0.000
C60-C63 Malignant neoplasms of male genital organs
0.682 0.318 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.682 0.318 0.000
M54.6 Pain in thoracic spine
0.682 0.318 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.681 0.319 0.000
S37 Injury of urinary and pelvic organs
0.681 0.319 0.000
S36 Injury of intra-abdominal organs
0.681 0.319 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.681 0.319 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.681 0.319 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.681 0.319 0.000
H35.9 Retinal disorder, unspecified
0.679 0.321 0.000
H73 Other disorders of tympanic membrane
0.678 0.321 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.678 0.322 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.678 0.322 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.678 0.322 0.000
H33.4 Traction detachment of retina
0.675 0.325 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.675 0.325 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.674 0.326 0.000
C01 Malignant neoplasm of base of tongue
0.674 0.326 0.000
Chapter XIV Diseases of the genitourinary system
0.672 0.328 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.671 0.329 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.670 0.330 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.670 0.330 0.000
T78.3 Angioneurotic oedema
0.670 0.330 0.000
M79.5 Residual foreign body in soft tissue
0.670 0.330 0.000
M65-M68 Disorders of synovium and tendon
0.670 0.330 0.000
H33.1 Retinoschisis and retinal cysts
0.669 0.331 0.000
H35.7 Separation of retinal layers
0.669 0.331 0.000
H21 Other disorders of iris and ciliary body
0.669 0.331 0.000
H16.0 Corneal ulcer
0.668 0.332 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.668 0.332 0.000
N13 Obstructive and reflux uropathy
0.667 0.333 0.000
T31 Burns classified according to extent of body surface involved
0.667 0.333 0.000
C18.8 Overlapping lesion of colon
0.666 0.334 0.000
N10-N16 Renal tubulo-interstitial diseases
0.666 0.334 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.665 0.335 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.664 0.336 0.000
T20.2 Burn of second degree of head and neck
0.664 0.336 0.000
M47.89 Other spondylosis (Site unspecified)
0.663 0.337 0.000
S52.10 Fracture of upper end of radius (closed)
0.663 0.337 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.663 0.337 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.662 0.338 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.662 0.338 0.000
S59 Other and unspecified injuries of forearm
0.661 0.339 0.000
S51 Open wound of forearm
0.661 0.339 0.000
C16 Malignant neoplasm of stomach
0.661 0.339 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.661 0.339 0.000
H30 Chorioretinal inflammation
0.661 0.339 0.000
X60-X84 Intentional self-harm
0.660 0.340 0.000
E00-E07 Disorders of thyroid gland
0.660 0.340 0.000
S12.2 Fracture of other specified cervical vertebra
0.660 0.340 0.000
S30.0 Contusion of lower back and pelvis
0.657 0.343 0.000
Q60-Q64 Congenital malformations of the urinary system
0.657 0.343 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.657 0.343 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.657 0.343 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.657 0.343 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.657 0.343 0.000
S31.0 Open wound of lower back and pelvis
0.656 0.343 0.000
S52.00 Fracture of upper end of ulna (closed)
0.657 0.343 0.000
S70 Superficial injury of hip and thigh
0.656 0.344 0.000
S82.9 Fracture of lower leg, part unspecified
0.656 0.344 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.654 0.346 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.653 0.347 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.653 0.347 0.000
H25-H28 Disorders of lens
0.651 0.349 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.651 0.349 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.651 0.349 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.651 0.349 0.000
T25 Burn and corrosion of ankle and foot
0.650 0.350 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.650 0.350 0.000
T75 Effects of other external causes
0.650 0.350 0.000
T74 Maltreatment syndromes
0.650 0.350 0.000
T73 Effects of other deprivation
0.650 0.350 0.000
T70 Effects of air pressure and water pressure
0.650 0.350 0.000
T69 Other effects of reduced temperature
0.650 0.350 0.000
T67 Effects of heat and light
0.650 0.350 0.000
T71 Asphyxiation
0.650 0.350 0.000
T66 Unspecified effects of radiation
0.650 0.350 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.649 0.351 0.000
H53-H54 Visual disturbances and blindness
0.649 0.351 0.000
Q07 Other congenital malformations of nervous system
0.648 0.352 0.000
E65-E68 Obesity and other hyperalimentation
0.648 0.352 0.000
C18.1 Appendix
0.646 0.354 0.000
S79 Other and unspecified injuries of hip and thigh
0.645 0.355 0.000
M79.6 Pain in limb
0.645 0.355 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.644 0.356 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.644 0.356 0.000
T87.4 Infection of amputation stump
0.644 0.356 0.000
M90 Osteopathies in diseases classified elsewhere
0.643 0.357 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.643 0.357 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.643 0.357 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.643 0.357 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.642 0.358 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.642 0.358 0.000
S82.5 Fracture of medial malleolus
0.641 0.359 0.000
M54.2 Cervicalgia
0.641 0.359 0.000
S91 Open wound of ankle and foot
0.641 0.359 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.640 0.360 0.000
E32 Diseases of thymus
0.640 0.360 0.000
E31 Polyglandular dysfunction
0.640 0.360 0.000
E30 Disorders of puberty, not elsewhere classified
0.640 0.360 0.000
E25 Adrenogenital disorders
0.640 0.360 0.000
E20 Hypoparathyroidism
0.640 0.360 0.000
M47.1 Other spondylosis with myelopathy
0.639 0.361 0.000
S10 Superficial injury of neck
0.639 0.361 0.000
T14.0 Superficial injury of unspecified body region
0.639 0.361 0.000
S58 Traumatic amputation of forearm
0.638 0.362 0.000
S57 Crushing injury of forearm
0.638 0.362 0.000
S56 Injury of muscle and tendon at forearm level
0.638 0.362 0.000
S55 Injury of blood vessels at forearm level
0.638 0.362 0.000
S54 Injury of nerves at forearm level
0.638 0.362 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.638 0.362 0.000
H18.1 Bullous keratopathy
0.638 0.362 0.000
D03 Melanoma in situ
0.638 0.362 0.000
T88.9 Complication of surgical and medical care, unspecified
0.636 0.363 0.000
T88.5 Other complications of anaesthesia
0.636 0.363 0.000
T88.3 Malignant hyperthermia due to anaesthesis
0.636 0.363 0.000
T88.2 Shock due to anaesthesia
0.636 0.363 0.000
T88.1 Other complications following immunisation, not elsewhere classified
0.636 0.363 0.000
T88.0 Infection following immunisation
0.636 0.363 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.636 0.364 0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.636 0.364 0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.636 0.364 0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.636 0.364 0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.636 0.364 0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.636 0.364 0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.636 0.364 0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)
0.636 0.364 0.000
D09.0 Bladder
0.636 0.364 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.635 0.365 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.634 0.366 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.634 0.366 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.634 0.366 0.000
H15 Disorders of sclera
0.634 0.366 0.000
E13 Other specified diabetes mellitus
0.634 0.366 0.000
H90.0 Conductive hearing loss, bilateral
0.633 0.367 0.000
M71 Other bursopathies
0.633 0.367 0.000
S82.00 Fracture of patella (closed)
0.633 0.367 0.000
H69 Other disorders of Eustachian tube
0.633 0.367 0.000
H72.8 Other perforations of tympanic membrane
0.633 0.367 0.000
S81.0 Open wound of knee
0.632 0.368 0.000
S17 Crushing injury of neck
0.631 0.368 0.000
S15 Injury of blood vessels at neck level
0.631 0.368 0.000
S11 Open wound of neck
0.631 0.368 0.000
S18 Traumatic amputation at neck level
0.631 0.368 0.000
S16 Injury of muscle and tendon at neck level
0.631 0.368 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.631 0.369 0.000
S32.5 Fracture of pubis
0.629 0.371 0.000
S81.9 Open wound of lower leg, part unspecified
0.629 0.371 0.000
H35.2 Other proliferative retinopathy
0.629 0.371 0.000
T82.1 Mechanical complication of cardiac electronic device
0.628 0.371 0.000
M51.3 Other specified intervertebral disk degeneration
0.628 0.372 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.628 0.372 0.000
M51.4 Schmorl's nodes
0.628 0.372 0.000
Q43 Other congenital malformations of intestine
0.628 0.372 0.000
S32.4 Fracture of acetabulum
0.628 0.372 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.628 0.372 0.000
V40-V49 Car occupant injured in transport accident
0.628 0.372 0.000
E11 Non-insulin-dependent diabetes mellitus
0.627 0.373 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.627 0.373 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.627 0.373 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.626 0.374 0.000
E28.2 Polycystic ovarian syndrome
0.625 0.375 0.000
Y00-Y09 Assault
0.625 0.375 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.623 0.377 0.000
C62 Malignant neoplasm of testis
0.622 0.378 0.000
C18.5 Splenic flexure
0.622 0.378 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.622 0.378 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.621 0.379 0.000
S52.3 Fracture of shaft of radius
0.621 0.379 0.000
H35.1 Retinopathy of prematurity
0.621 0.379 0.000
H16.2 Keratoconjunctivitis
0.620 0.380 0.000
E26 Hyperaldosteronism
0.620 0.380 0.000
M46.8 Other specified inflammatory spondylopathies
0.620 0.380 0.000
M46.5 Other infective spondylopathies
0.620 0.380 0.000
M46.4 Discitis, unspecified
0.620 0.380 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.620 0.380 0.000
M46.2 Osteomyelitis of vertebra
0.620 0.380 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.620 0.380 0.000
M46.0 Spinal enthesopathy
0.620 0.380 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.620 0.380 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.620 0.380 0.000
T90.9 Sequelae of unspecified injury of head
0.620 0.380 0.000
D06.9 Cervix, unspecified
0.619 0.381 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.618 0.382 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.618 0.382 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.618 0.382 0.000
T20.0 Burn of unspecified degree of head and neck
0.617 0.382 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.617 0.383 0.000
C73 Malignant neoplasm of thyroid gland
0.617 0.383 0.000
M43 Other deforming dorsopathies
0.616 0.384 0.000
T78.9 Adverse effect, unspecified
0.616 0.384 0.000
T78.8 Other adverse effects, not elsewhere classified
0.616 0.384 0.000
S12.7 Multiple fractures of cervical spine
0.613 0.387 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.613 0.387 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.612 0.388 0.000
M51.2 Other specified intervertebral disk displacement
0.612 0.388 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.612 0.388 0.000
E29.1 Testicular hypofunction
0.612 0.388 0.000
H92 Otalgia and effusion of ear
0.612 0.388 0.000
W50-W64 Exposure to animate mechanical forces
0.611 0.388 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.611 0.389 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.610 0.390 0.000
S82.8 Fractures of other parts of lower leg
0.610 0.390 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.609 0.391 0.000
S82.4 Fracture of fibula alone
0.609 0.391 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.608 0.392 0.000
H18.8 Other specified disorders of cornea
0.608 0.392 0.000
H18.4 Corneal degeneration
0.608 0.392 0.000
E34.0 Carcinoid syndrome
0.608 0.392 0.000
M87 Osteonecrosis
0.608 0.392 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.607 0.393 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.607 0.393 0.000
C21 Malignant neoplasm of anus and anal canal
0.607 0.393 0.000
S98 Traumatic amputation of ankle and foot
0.607 0.393 0.000
S97 Crushing injury of ankle and foot
0.607 0.393 0.000
S95 Injury of blood vessels at ankle and foot level
0.607 0.393 0.000
S94 Injury of nerves at ankle and foot level
0.607 0.393 0.000
S32.3 Fracture of ilium
0.606 0.394 0.000
S40-S49 Injuries to the shoulder and upper arm
0.606 0.394 0.000
H16.9 Keratitis, unspecified
0.606 0.394 0.000
H35.0 Background retinopathy and retinal vascular changes
0.606 0.394 0.000
W05 Fall involving wheelchair
0.606 0.394 0.000
S89 Other and unspecified injuries of lower leg
0.605 0.395 0.000
S60-S69 Injuries to the wrist and hand
0.605 0.395 0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis
0.604 0.395 0.000
S30.2 Contusion of external genital organs
0.604 0.395 0.000
S14.1 Other and unspecified injuries of cervical spinal cord
0.604 0.396 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.604 0.396 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.604 0.396 0.000
S52.4 Fracture of shafts of both ulna and radius
0.604 0.396 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.603 0.397 0.000
E21.4 Other specified disorders of parathyroid gland
0.603 0.397 0.000
E21.2 Other hyperparathyroidism
0.603 0.397 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.603 0.397 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.603 0.397 0.000
S52.01 Fracture of upper end of ulna (open)
0.602 0.398 0.000
H66.4 Suppurative otitis media, unspecified
0.601 0.399 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.601 0.399 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.601 0.399 0.000
H66.0 Acute suppurative otitis media
0.601 0.399 0.000
Q05 Spina bifida
0.601 0.399 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.601 0.399 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.601 0.399 0.000
E14.9 Without complications
0.601 0.399 0.000
Q24.9 Congenital malformation of the heart, unspecified
0.600 0.400 0.000
S52.2 Fracture of shaft of ulna
0.600 0.400 0.000
M62 Other disorders of muscle
0.600 0.400 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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