TreeWAS – Variant ID: rs79531373

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
S00-S09 Injuries to the head	0.998	0.002
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.995	0.005
S00 Superficial injury of head	0.983	0.017
M80-M85 Disorders of bone density and structure	0.982	0.018
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.982	0.018
Chapter XX External causes of morbidity and mortality	0.974	0.026
S40-S49 Injuries to the shoulder and upper arm	0.971	0.029
Chapter XII Diseases of the skin and subcutaneous tissue	0.969	0.031
S32 Fracture of lumbar spine and pelvis	0.963	0.037
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.961	0.039
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.960	0.040
Chapter XXI Factors influencing health status and contact with health services	0.955	0.045
R20 Disturbances of skin sensation	0.955	0.045
T93 Sequelae of injuries of lower limb	0.953	0.047
S00.8 Superficial injury of other parts of head	0.951	0.049
M80 Osteoporosis with pathological fracture	0.949	0.051
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.949	0.051
S42 Fracture of shoulder and upper arm	0.947	0.053
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.942	0.058
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.925	0.075
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.923	0.077
T15-T19 Effects of foreign body entering through natural orifice	0.923	0.077
M45-M49 Spondylopathies	0.922	0.078
M80.9 Unspecified osteoporosis with pathological fracture	0.921	0.079
T93.2 Sequelae of other fractures of lower limb	0.920	0.080
Chapter VII Diseases of the eye and adnexa	0.918	0.082
R20.8 Other and unspecified disturbances of skin sensation	0.916	0.084
L40-L45 Papulosquamous disorders	0.915	0.085
R20.2 Paraesthesia of skin	0.915	0.085
S02 Fracture of skull and facial bones	0.912	0.088
Z87 Personal history of other diseases and conditions	0.909	0.091
L00-L08 Infections of the skin and subcutaneous tissue	0.906	0.094
L03 Cellulitis	0.895	0.105
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.895	0.105
M84 Disorders of continuity of bone	0.890	0.110
L03.1 Cellulitis of other parts of limb	0.889	0.111
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.884	0.116
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.884	0.116
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.882	0.118
S32.1 Fracture of sacrum	0.881	0.119
L20-L30 Dermatitis and eczema	0.881	0.119
Z87.8 Personal history of other specified conditions	0.881	0.119
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.880	0.120
S06 Intracranial injury	0.879	0.121
M40-M43 Deforming dorsopathies	0.876	0.124
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.874	0.126
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.874	0.126
Chapter VIII Diseases of the ear and mastoid process	0.874	0.126
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.873	0.127
S42.2 Fracture of upper end of humerus	0.871	0.129
M48 Other spondylopathies	0.870	0.130
S01 Open wound of head	0.867	0.133
S10-S19 Injuries to the neck	0.864	0.135
Z93 Artificial opening status	0.861	0.139
M50-M54 Other dorsopathies	0.854	0.146
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.850	0.150
Q20-Q28 Congenital malformations of the circulatory system	0.850	0.150
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.848	0.152
S00.7 Multiple superficial injuries of head	0.845	0.155
Z40-Z54 Persons encountering health services for specific procedures and health care	0.840	0.160
T66-T78 Other and unspecified effects of external causes	0.838	0.161
Z63 Other problems related to primary support group, including family circumstances	0.836	0.164
R22.1 Localised swelling, mass and lump, neck	0.835	0.165
S30 Superficial injury of abdomen, lower back and pelvis	0.833	0.167
L40 Psoriasis	0.830	0.170
Chapter XV Pregnancy, childbirth and the puerperium	0.830	0.170
Chapter I Certain infectious and parasitic diseases	0.828	0.172
Y45.0 Opioids and related analgesics	0.826	0.174
S32.10 Fracture of sacrum (closed)	0.823	0.177
Q50-Q56 Congenital malformations of genital organs	0.823	0.177
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.823	0.177
H53-H54 Visual disturbances and blindness	0.821	0.179
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.821	0.179
Z87.0 Personal history of diseases of the respiratory system	0.820	0.180
T91 Sequelae of injuries of neck and trunk	0.820	0.180
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.820	0.180
S42.20 Fracture of upper end of humerus (closed)	0.817	0.183
S01.2 Open wound of nose	0.816	0.184
T17 Foreign body in respiratory tract	0.815	0.185
S00.5 Superficial injury of lip and oral cavity	0.815	0.185
O00-O08 Pregnancy with abortive outcome	0.814	0.186
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.813	0.187
S90-S99 Injuries to the ankle and foot	0.812	0.188
S02.1 Fracture of base of skull	0.810	0.190
R23 Other skin changes	0.808	0.192
O04 Medical abortion	0.807	0.193
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.807	0.193
Chapter XI Diseases of the digestive system	0.807	0.193
S32.5 Fracture of pubis	0.805	0.194
S00.3 Superficial injury of nose	0.805	0.195
S32.7 Multiple fractures of lumbar spine and pelvis	0.803	0.197
M84.1 Nonunion of fracture [pseudarthrosis]	0.801	0.199
O04.9 Complete or unspecified, without complication	0.800	0.200
L43 Lichen planus	0.797	0.203
M41 Scoliosis	0.797	0.203
M48.0 Spinal stenosis	0.795	0.205
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.794	0.206
Z70-Z76 Persons encountering health services in other circumstances	0.793	0.207
T90 Sequelae of injuries of head	0.792	0.208
K90-K93 Other diseases of the digestive system	0.790	0.210
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.790	0.210
S49 Other and unspecified injuries of shoulder and upper arm	0.790	0.210
T18 Foreign body in alimentary tract	0.789	0.210
S00.1 Contusion of eyelid and periocular area	0.788	0.212
H65-H75 Diseases of middle ear and mastoid	0.787	0.213
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.784	0.216
R82 Other abnormal findings in urine	0.782	0.218
Z89 Acquired absence of limb	0.781	0.219
S42.0 Fracture of clavicle	0.781	0.219
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.780	0.220
Y84.2 Radiological procedure and radiotherapy	0.779	0.221
Z80 Family history of malignant neoplasm	0.779	0.221
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.778	0.222
R80 Isolated proteinuria	0.777	0.223
M46 Other inflammatory spondylopathies	0.776	0.224
H10-H13 Disorders of conjunctiva	0.773	0.227
S42.3 Fracture of shaft of humerus	0.773	0.227
R20.0 Anaesthesia of skin	0.771	0.229
Y40 Systemic antibiotics	0.768	0.232
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.768	0.232
Z86 Personal history of certain other diseases	0.764	0.236
M51 Other intervertebral disk disorders	0.763	0.237
Z46 Fitting and adjustment of other devices	0.760	0.240
M15-M19 Arthrosis	0.760	0.240
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.759	0.241
S70-S79 Injuries to the hip and thigh	0.759	0.241
V40-V49 Car occupant injured in transport accident	0.759	0.241
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.758	0.242
T93.1 Sequelae of fracture of femur	0.755	0.245
S80-S89 Injuries to the knee and lower leg	0.753	0.247
R50-R69 General symptoms and signs	0.753	0.247
T20-T25 Burns and corrosions of external body surface, specified by site	0.749	0.251
M60-M63 Disorders of muscles	0.748	0.251
L27 Dermatitis due to substances taken internally	0.748	0.252
T51 Toxic effect of alcohol	0.748	0.252
S06.0 Concussion	0.747	0.253
M48.5 Collapsed vertebra, not elsewhere classified	0.745	0.254
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.745	0.255
S32.0 Fracture of lumbar vertebra	0.744	0.256
M86-M90 Other osteopathies	0.744	0.256
K70-K77 Diseases of liver	0.743	0.257
H46-H48 Disorders of optic nerve and visual pathways	0.740	0.260
S42.9 Fracture of shoulder girdle, part unspecified	0.740	0.260
R51 Headache	0.740	0.260
M48.02 Spinal stenosis (Cervical region)	0.740	0.260
S41 Open wound of shoulder and upper arm	0.738	0.262
Z48 Other surgical follow-up care	0.738	0.262
S02.10 Fracture of base of skull (closed)	0.737	0.262
S42.1 Fracture of scapula	0.737	0.263
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.735	0.265
S12 Fracture of neck	0.735	0.265
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.734	0.266
Z97 Presence of other devices	0.734	0.266
Z80.0 Family history of malignant neoplasm of digestive organs	0.733	0.267
Z85 Personal history of malignant neoplasm	0.733	0.267
L30 Other dermatitis	0.733	0.267
T59 Toxic effect of other gases, fumes and vapours	0.732	0.268
Z86.4 Personal history of psychoactive substance abuse	0.731	0.269
H65 Nonsuppurative otitis media	0.730	0.270
W20-W49 Exposure to inanimate mechanical forces	0.729	0.271
Z93.2 Ileostomy status	0.726	0.274
M80.0 Postmenopausal osteoporosis with pathological fracture	0.726	0.274
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.725	0.275
H90-H95 Other disorders of ear	0.724	0.276
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.724	0.276
M85 Other disorders of bone density and structure	0.722	0.278
M41.9 Scoliosis, unspecified	0.721	0.279
R22.7 Localised swelling, mass and lump, multiple sites	0.721	0.279
Z40 Prophylactic surgery	0.720	0.280
Z47 Other orthopaedic follow-up care	0.719	0.281
Q24 Other congenital malformations of heart	0.719	0.281
S01.9 Open wound of head, part unspecified	0.718	0.282
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Z93.4 Other artificial openings of gastro-intestinal tract status	0.716	0.284
S08 Traumatic amputation of part of head	0.716	0.284
S07 Crushing injury of head	0.716	0.284
S04 Injury of cranial nerves	0.716	0.284
S03 Dislocation, sprain and strain of joints and ligaments of head	0.716	0.284
R23.8 Other and unspecified skin changes	0.714	0.286
W00-W19 Falls	0.714	0.286
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.713	0.287
S37 Injury of urinary and pelvic organs	0.713	0.287
S36 Injury of intra-abdominal organs	0.713	0.287
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.713	0.287
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.713	0.287
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.713	0.287
S31 Open wound of abdomen, lower back and pelvis	0.713	0.287
L43.9 Lichen planus, unspecified	0.713	0.287
Q80-Q89 Other congenital malformations	0.713	0.287
Z93.3 Colostomy status	0.711	0.289
S06.6 Traumatic subarachnoid haemorrhage	0.711	0.289
Z91 Personal history of risk-factors, not elsewhere classified	0.711	0.289
Z98 Other postsurgical states	0.710	0.290
H54 Blindness and low vision	0.709	0.291
Z93.1 Gastrostomy status	0.709	0.291
S02.4 Fracture of malar and maxillary bones	0.708	0.292
R73 Elevated blood glucose level	0.708	0.292
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.707	0.293
L03.9 Cellulitis, unspecified	0.707	0.293
S00.4 Superficial injury of ear	0.705	0.295
M83 Adult osteomalacia	0.704	0.296
M82 Osteoporosis in diseases classified elsewhere	0.704	0.296
S42.4 Fracture of lower end of humerus	0.704	0.296
Y44 Agents primarily affecting blood constituents	0.704	0.296
T98 Sequelae of other and unspecified effects of external causes	0.704	0.296
T95 Sequelae of burns, corrosions and frostbite	0.704	0.296
T94 Sequelae of injuries involving multiple and unspecified body regions	0.704	0.296
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.704	0.296
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.704	0.296
M84.0 Malunion of fracture	0.704	0.296
L40.8 Other psoriasis	0.702	0.298
L40.0 Psoriasis vulgaris	0.702	0.298
Z63.7 Other stressful life events affecting family and household	0.702	0.298
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.701	0.299
X50-X57 Overexertion, travel and privation	0.701	0.299
K91.4 Colostomy and enterostomy malfunction	0.700	0.300
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.699	0.301
M81 Osteoporosis without pathological fracture	0.699	0.301
Y35-Y36 Legal intervention and operations of war	0.698	0.301
Y10-Y34 Event of undetermined intent	0.698	0.301
Y00-Y09 Assault	0.698	0.301
X85-X99 Assault	0.698	0.301
X58-X59 Accidental exposure to other and unspecified factors	0.698	0.301
X30-X39 Exposure to forces of nature	0.698	0.301
X20-X29 Contact with venomous animals and plants	0.698	0.301
X10-X19 Contact with heat and hot substances	0.698	0.301
X00-X09 Exposure to smoke, fire and flames	0.698	0.301
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.698	0.301
W75-W84 Other accidental threats to breathing	0.698	0.301
W65-W74 Accidental drowning and submersion	0.698	0.301
W50-W64 Exposure to animate mechanical forces	0.698	0.301
V98-V99 Other and unspecified transport accidents	0.698	0.301
V95-V97 Air and space transport accidents	0.698	0.301
V90-V94 Water transport accidents	0.698	0.301
V70-V79 Bus occupant injured in transport accident	0.698	0.301
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.698	0.301
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.698	0.301
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.698	0.301
V01-V09 Pedestrian injured in transport accident	0.698	0.301
Z43 Attention to artificial openings	0.698	0.302
Y52 Agents primarily affecting the cardiovascular system	0.698	0.302
S02.0 Fracture of vault of skull	0.698	0.302
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.697	0.303
M65-M68 Disorders of synovium and tendon	0.696	0.304
S48 Traumatic amputation of shoulder and upper arm	0.696	0.304
S46 Injury of muscle and tendon at shoulder and upper arm level	0.696	0.304
S45 Injury of blood vessels at shoulder and upper arm level	0.696	0.304
S44 Injury of nerves at shoulder and upper arm level	0.696	0.304
S47 Crushing injury of shoulder and upper arm	0.696	0.304
T31 Burns classified according to extent of body surface involved	0.696	0.304
S09 Other and unspecified injuries of head	0.696	0.304
S50-S59 Injuries to the elbow and forearm	0.695	0.305
Z63.4 Disappearance and death of family member	0.695	0.305
L10-L14 Bullous disorders	0.694	0.305
T18.1 Foreign body in oesophagus	0.694	0.306
M70-M79 Other soft tissue disorders	0.694	0.306
Z93.0 Tracheostomy status	0.693	0.306
S00.2 Other superficial injuries of eyelid and periocular area	0.693	0.307
S32.50 Fracture of pubis (closed)	0.693	0.307
S02.3 Fracture of orbital floor	0.692	0.308
X60-X84 Intentional self-harm	0.692	0.308
M50 Cervical disk disorders	0.692	0.308
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.691	0.309
M00-M03 Infectious arthropathies	0.691	0.309
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.690	0.310
S32.3 Fracture of ilium	0.690	0.310
S32.2 Fracture of coccyx	0.690	0.310
S40 Superficial injury of shoulder and upper arm	0.690	0.310
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.689	0.311
H65.3 Chronic mucoid otitis media	0.689	0.311
R95-R99 Ill-defined and unknown causes of mortality	0.689	0.311
Y45.8 Other analgesics and antipyretics	0.689	0.311
R77 Other abnormalities of plasma proteins	0.688	0.312
K50-K52 Noninfective enteritis and colitis	0.687	0.313
R87 Abnormal findings in specimens from female genital organs	0.686	0.314
Z63.8 Other specified problems related to primary support group	0.686	0.314
H20 Iridocyclitis	0.685	0.315
S02.8 Fractures of other skull and facial bones	0.685	0.315
T92 Sequelae of injuries of upper limb	0.685	0.315
R20.3 Hyperaesthesia	0.685	0.315
R20.1 Hypoaesthesia of skin	0.685	0.315
Q00-Q07 Congenital malformations of the nervous system	0.685	0.315
K91.3 Postoperative intestinal obstruction	0.684	0.316
S06.4 Epidural haemorrhage	0.684	0.316
Y60-Y69 Misadventures to patients during surgical and medical care	0.684	0.316
R82.8 Abnormal findings on cytological and histological examination of urine	0.684	0.316
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.683	0.317
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.683	0.317
T93.4 Sequelae of injury of nerve of lower limb	0.683	0.317
T93.0 Sequelae of open wound of lower limb	0.683	0.317
T17.2 Foreign body in pharynx	0.683	0.317
M91-M94 Chondropathies	0.682	0.318
R22.9 Localised swelling, mass and lump, unspecified	0.682	0.318
S05 Injury of eye and orbit	0.682	0.318
B95-B98 Bacterial, viral and other infectious agents	0.681	0.319
M80.8 Other osteoporosis with pathological fracture	0.681	0.319
M80.5 Idiopathic osteoporosis with pathological fracture	0.681	0.319
M80.4 Drug-induced osteoporosis with pathological fracture	0.681	0.319
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.681	0.319
M80.2 Osteoporosis of disuse with pathological fracture	0.681	0.319
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.681	0.319
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.680	0.320
Q35-Q37 Cleft lip and cleft palate	0.680	0.320
Q30-Q34 Congenital malformations of the respiratory system	0.680	0.320
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.680	0.320
T17.9 Foreign body in respiratory tract, part unspecified	0.679	0.320
L29 Pruritus	0.679	0.321
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.679	0.321
S42.8 Fracture of other parts of shoulder and upper arm	0.679	0.321
S42.7 Multiple fractures of clavicle, scapula and humerus	0.679	0.321
S02.6 Fracture of mandible	0.678	0.322
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.678	0.322
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.678	0.322
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.678	0.322
H55-H59 Other disorders of eye and adnexa	0.678	0.322
Z94 Transplanted organ and tissue status	0.677	0.323
S00.0 Superficial injury of scalp	0.677	0.323
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.677	0.323
H53 Visual disturbances	0.677	0.323
H43-H45 Disorders of vitreous body and globe	0.677	0.323
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.676	0.324
Z63.0 Problems in relationship with spouse or partner	0.676	0.324
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.675	0.324
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.675	0.325
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.675	0.325
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.675	0.325
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.675	0.325
T36-T50 Poisoning by drugs, medicaments and biological substances	0.674	0.326
Q25 Congenital malformations of great arteries	0.674	0.326
T68 Hypothermia	0.674	0.326
S32.4 Fracture of acetabulum	0.673	0.327
Z89.5 Acquired absence of leg at or below knee	0.672	0.328
T78 Adverse effects, not elsewhere classified	0.671	0.329
Z74 Problems related to care-provider dependency	0.671	0.329
X40-X49 Accidental poisoning by and exposure to noxious substances	0.671	0.329
S01.4 Open wound of cheek and temporomandibular area	0.671	0.329
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.671	0.329
B15-B19 Viral hepatitis	0.668	0.332
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.668	0.332
V80-V89 Other land transport accidents	0.668	0.332
Z64 Problems related to certain psychosocial circumstances	0.667	0.333
R81 Glycosuria	0.667	0.333
S10 Superficial injury of neck	0.667	0.333
R72 Abnormality of white blood cells, not elsewhere classified	0.666	0.334
Z81 Family history of mental and behavioural disorders	0.665	0.334
S20-S29 Injuries to the thorax	0.665	0.335
Q60-Q64 Congenital malformations of the urinary system	0.664	0.336
H21 Other disorders of iris and ciliary body	0.663	0.337
Y59 Other and unspecified vaccines and biological substances	0.662	0.338
Y58 Bacterial vaccines	0.662	0.338
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.662	0.338
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.662	0.338
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.662	0.338
Y53 Agents primarily affecting the gastro-intestinal system	0.662	0.338
Y50 Central nervous system stimulants, not elsewhere classified	0.662	0.338
Y49 Psychotropic drugs, not elsewhere classified	0.662	0.338
Y48 Anaesthetics and therapeutic gases	0.662	0.338
Y47 Sedatives, hypnotics and antianxiety drugs	0.662	0.338
Y46 Antiepileptics and anti-Parkinsonism drugs	0.662	0.338
T19 Foreign body in genito-urinary tract	0.662	0.338
T15 Foreign body on external eye	0.662	0.338
T16 Foreign body in ear	0.662	0.338
S42.00 Fracture of clavicle (closed)	0.661	0.339
M49 Spondylopathies in diseases classified elsewhere	0.661	0.339
T91.1 Sequelae of fracture of spine	0.661	0.339
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.660	0.340
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.660	0.340
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.660	0.340
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.660	0.340
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.660	0.340
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.660	0.340
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.660	0.340
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.660	0.340
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.660	0.340
Y45.1 Salicylates	0.660	0.340
S49.9 Unspecified injury of shoulder and upper arm	0.660	0.340
O04.4 Incomplete, without complication	0.660	0.340
Chapter IV Endocrine, nutritional and metabolic diseases	0.659	0.341
Q38-Q45 Other congenital malformations of the digestive system	0.659	0.341
S91 Open wound of ankle and foot	0.658	0.342
Chapter XXII Codes for special purposes	0.657	0.343
Z86.1 Personal history of infectious and parasitic diseases	0.657	0.343
L44 Other papulosquamous disorders	0.656	0.344
L41 Parapsoriasis	0.656	0.344
L45 Papulosquamous disorders in diseases classified elsewhere	0.656	0.344
L42 Pityriasis rosea	0.656	0.344
M46.9 Inflammatory spondylopathy, unspecified	0.656	0.344
B50-B64 Protozoal diseases	0.655	0.345
T79-T79 Certain early complications of trauma	0.655	0.345
Z49 Care involving dialysis	0.655	0.345
S02.9 Fracture of skull and facial bones, part unspecified	0.654	0.346
S02.7 Multiple fractures involving skull and facial bones	0.654	0.346
Z58 Problems related to physical environment	0.653	0.347
S06.00 Concussion (without open intracranial wound)	0.652	0.348
Z87.6 Personal history of certain conditions arising in the perinatal period	0.652	0.348
Q21 Congenital malformations of cardiac septa	0.652	0.348
T93.9 Sequelae of unspecified injury of lower limb	0.651	0.349
T91.3 Sequelae of injury of spinal cord	0.651	0.349
Z86.5 Personal history of other mental and behavioural disorders	0.650	0.350
L04 Acute lymphadenitis	0.650	0.350
L01 Impetigo	0.650	0.350
L00 Staphylococcal scalded skin syndrome	0.650	0.350
Y41 Other systemic anti-infectives and antiparasitics	0.649	0.351
Z84 Family history of other conditions	0.649	0.351
S42.30 Fracture of shaft of humerus (closed)	0.648	0.352
K75 Other inflammatory liver diseases	0.648	0.352
S06.2 Diffuse brain injury	0.647	0.353
H72 Perforation of tympanic membrane	0.647	0.353
H11 Other disorders of conjunctiva	0.647	0.353
Q51 Congenital malformations of uterus and cervix	0.647	0.353
O85-O92 Complications predominantly related to the puerperium	0.647	0.353
Z41 Procedures for purposes other than remedying health state	0.646	0.354
M05-M14 Inflammatory polyarthropathies	0.645	0.355
T51.0 Ethanol	0.645	0.355
Q23 Congenital malformations of aortic and mitral valves	0.645	0.355
Y51 Drugs primarily affecting the autonomic nervous system	0.644	0.355
L08 Other local infections of skin and subcutaneous tissue	0.644	0.356
S82 Fracture of lower leg, including ankle	0.644	0.356
Z48.8 Other specified surgical follow-up care	0.644	0.356
Y57 Other and unspecified drugs and medicaments	0.643	0.356
M51.9 Intervertebral disk disorder, unspecified	0.643	0.357
L27.0 Generalised skin eruption due to drugs and medicaments	0.643	0.357
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.643	0.357
R52 Pain, not elsewhere classified	0.642	0.358
K90 Intestinal malabsorption	0.641	0.359
Z98.1 Arthrodesis status	0.641	0.359
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.641	0.359
L03.8 Cellulitis of other sites	0.640	0.360
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.640	0.360
S01.8 Open wound of other parts of head	0.640	0.360
K91.0 Vomiting following gastro-intestinal surgery	0.640	0.360
M48.09 Spinal stenosis (Site unspecified)	0.640	0.360
L40.5 Arthropathic psoriasis	0.639	0.361
M19 Other arthrosis	0.638	0.362
M84.9 Disorder of continuity of bone, unspecified	0.638	0.362
M84.8 Other disorders of continuity of bone	0.638	0.362
M84.4 Pathological fracture, not elsewhere classified	0.638	0.362
M84.3 Stress fracture, not elsewhere classified	0.638	0.362
M84.2 Delayed union of fracture	0.638	0.362
L28 Lichen simplex chronicus and prurigo	0.638	0.362
Z46.7 Fitting and adjustment of orthopaedic device	0.636	0.364
V20-V29 Motorcycle rider injured in transport accident	0.636	0.364
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.636	0.364
A15-A19 Tuberculosis	0.636	0.364
Z46.8 Fitting and adjustment of other specified devices	0.635	0.365
Z42 Follow-up care involving plastic surgery	0.635	0.365
L50-L54 Urticaria and erythema	0.634	0.365
T65 Toxic effect of other and unspecified substances	0.634	0.366
T63 Toxic effect of contact with venomous animals	0.634	0.366
T62 Toxic effect of other noxious substances eaten as food	0.634	0.366
T61 Toxic effect of noxious substances eaten as seafood	0.634	0.366
T60 Toxic effect of pesticides	0.634	0.366
T57 Toxic effect of other inorganic substances	0.634	0.366
T56 Toxic effect of metals	0.634	0.366
T54 Toxic effect of corrosive substances	0.634	0.366
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.634	0.366
T52 Toxic effect of organic solvents	0.634	0.366
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.634	0.366
T58 Toxic effect of carbon monoxide	0.634	0.366
T55 Toxic effect of soaps and detergents	0.634	0.366
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.634	0.366
Z65 Problems related to other psychosocial circumstances	0.633	0.366
Z62 Other problems related to upbringing	0.633	0.366
Z61 Problems related to negative life events in childhood	0.633	0.366
Z59 Problems related to housing and economic circumstances	0.633	0.366
Z56 Problems related to employment and unemployment	0.633	0.366
Z55 Problems related to education and literacy	0.633	0.366
R23.1 Pallor	0.633	0.367
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.633	0.367
Y45.5 4-Aminophenol derivatives	0.633	0.367
Y45.4 Antirheumatics	0.633	0.367
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.633	0.367
S12.2 Fracture of other specified cervical vertebra	0.632	0.368
S32.11 Fracture of sacrum (open)	0.632	0.368
S19 Other and unspecified injuries of neck	0.632	0.368
L25 Unspecified contact dermatitis	0.632	0.368
L24 Irritant contact dermatitis	0.632	0.368
L23 Allergic contact dermatitis	0.632	0.368
L21 Seborrhoeic dermatitis	0.632	0.368
L20 Atopic dermatitis	0.632	0.368
L26 Exfoliative dermatitis	0.632	0.368
L22 Diaper [napkin] dermatitis	0.632	0.368
S06.3 Focal brain injury	0.632	0.368
Q27 Other congenital malformations of peripheral vascular system	0.631	0.369
R68 Other general symptoms and signs	0.631	0.369
Y84.0 Cardiac catheterisation	0.631	0.369
S06.9 Intracranial injury, unspecified	0.630	0.369
S06.8 Other intracranial injuries	0.630	0.369
S06.7 Intracranial injury with prolonged coma	0.630	0.369
S06.1 Traumatic cerebral oedema	0.630	0.369
M41.8 Other forms of scoliosis	0.630	0.370
Q54 Hypospadias	0.630	0.370
Y45.2 Propionic acid derivatives	0.630	0.370
M42 Spinal osteochondrosis	0.628	0.371

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations