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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79685532
log Bayes Factor = 10.6212
Chromosome 18   position 77,725,683  (GRCh37) Explore rs79685532 on Ensembl!
Variant rs79685532 is part of Cluster X0061

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
R07.4 Chest pain, unspecified
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
J44 Other chronic obstructive pulmonary disease
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.996 0.004 0.000
J47 Bronchiectasis
0.993 0.007 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.992 0.008 0.000
R07 Pain in throat and chest
0.991 0.009 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.988 0.012 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.988 0.012 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.987 0.013 0.000
F17.1 Harmful use
0.985 0.015 0.000
Chapter VI Diseases of the nervous system
0.982 0.018 0.000
E70-E90 Metabolic disorders
0.976 0.024 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.970 0.030 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.969 0.031 0.000
F30-F39 Mood [affective] disorders
0.966 0.034 0.000
R04 Haemorrhage from respiratory passages
0.960 0.040 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.954 0.046 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.951 0.049 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.948 0.052 0.000
T42.4 Benzodiazepines
0.948 0.052 0.000
E20-E35 Disorders of other endocrine glands
0.946 0.054 0.000
R29.6 Tendency to fall, not elsewhere classified
0.944 0.056 0.000
J09-J18 Influenza and pneumonia
0.944 0.056 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.943 0.057 0.000
V10-V19 Pedal cyclist injured in transport accident
0.941 0.059 0.000
E87.2 Acidosis
0.938 0.062 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.933 0.067 0.000
S90-S99 Injuries to the ankle and foot
0.933 0.067 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.931 0.069 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.930 0.070 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.925 0.075 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.925 0.075 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.922 0.078 0.000
F31 Bipolar affective disorder
0.917 0.083 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.907 0.093 0.000
R04.2 Haemoptysis
0.905 0.095 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.893 0.107 0.000
T39.1 4-Aminophenol derivatives
0.891 0.109 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.891 0.109 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.890 0.110 0.000
E50-E64 Other nutritional deficiencies
0.888 0.112 0.000
M50-M54 Other dorsopathies
0.885 0.115 0.000
M54 Dorsalgia
0.885 0.115 0.000
E16 Other disorders of pancreatic internal secretion
0.882 0.118 0.000
G35 Multiple sclerosis
0.880 0.120 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.880 0.120 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.880 0.120 0.000
Chapter XXII Codes for special purposes
0.876 0.124 0.000
Chapter VIII Diseases of the ear and mastoid process
0.872 0.127 0.000
S10-S19 Injuries to the neck
0.872 0.128 0.000
G20-G26 Extrapyramidal and movement disorders
0.866 0.134 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.864 0.136 0.000
R04.0 Epistaxis
0.859 0.141 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.856 0.144 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.855 0.145 0.000
M54.5 Low back pain
0.854 0.146 0.000
F32 Depressive episode
0.853 0.147 0.000
E88 Other metabolic disorders
0.852 0.148 0.000
Q60-Q64 Congenital malformations of the urinary system
0.852 0.148 0.000
R40 Somnolence, stupor and coma
0.851 0.149 0.000
M54.57 Low back pain (Lumbosacral region)
0.849 0.151 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.847 0.153 0.000
S92 Fracture of foot, except ankle
0.844 0.156 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.843 0.157 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.841 0.159 0.000
V18.0 Driver injured in nontraffic accident
0.837 0.162 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.837 0.163 0.000
R45 Symptoms and signs involving emotional state
0.836 0.164 0.000
J18 Pneumonia, organism unspecified
0.835 0.165 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.834 0.166 0.000
S91 Open wound of ankle and foot
0.830 0.170 0.000
M54.6 Pain in thoracic spine
0.827 0.173 0.000
J42 Unspecified chronic bronchitis
0.824 0.176 0.000
J43 Emphysema
0.824 0.176 0.000
W50-W64 Exposure to animate mechanical forces
0.822 0.178 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.820 0.180 0.000
E53 Deficiency of other B group vitamins
0.819 0.181 0.000
E16.2 Hypoglycaemia, unspecified
0.817 0.183 0.000
F11 Mental and behavioural disorders due to use of opioids
0.816 0.184 0.000
S50-S59 Injuries to the elbow and forearm
0.814 0.186 0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.814 0.186 0.000
J95-J99 Other diseases of the respiratory system
0.812 0.188 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.808 0.192 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.807 0.193 0.000
M54.9 Dorsalgia, unspecified
0.807 0.193 0.000
G20 Parkinson's disease
0.805 0.195 0.000
E22 Hyperfunction of pituitary gland
0.803 0.197 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.801 0.199 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.799 0.201 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.798 0.202 0.000
R07.0 Pain in throat
0.797 0.203 0.000
X20-X29 Contact with venomous animals and plants
0.797 0.203 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.795 0.205 0.000
H65-H75 Diseases of middle ear and mastoid
0.793 0.207 0.000
X60-X84 Intentional self-harm
0.792 0.208 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.790 0.210 0.000
F60-F69 Disorders of adult personality and behaviour
0.790 0.210 0.000
E27 Other disorders of adrenal gland
0.787 0.213 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.785 0.215 0.000
E28 Ovarian dysfunction
0.782 0.218 0.000
T66-T78 Other and unspecified effects of external causes
0.782 0.218 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.781 0.219 0.000
R46 Symptoms and signs involving appearance and behaviour
0.781 0.219 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.778 0.222 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.778 0.222 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.775 0.225 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.773 0.227 0.000
M54.4 Lumbago with sciatica
0.771 0.229 0.000
E53.8 Deficiency of other specified B group vitamins
0.769 0.231 0.000
J17 Pneumonia in diseases classified elsewhere
0.769 0.231 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.769 0.231 0.000
X41.9 Unspecified place
0.768 0.232 0.000
F31.9 Bipolar affective disorder, unspecified
0.768 0.232 0.000
J18.9 Pneumonia, unspecified
0.765 0.235 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.764 0.236 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.764 0.236 0.000
E85 Amyloidosis
0.763 0.236 0.000
F32.9 Depressive episode, unspecified
0.761 0.239 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.761 0.239 0.000
R07.1 Chest pain on breathing
0.761 0.239 0.000
G57 Mononeuropathies of lower limb
0.758 0.242 0.000
F99-F99 Unspecified mental disorder
0.758 0.242 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.758 0.242 0.000
G37 Other demyelinating diseases of central nervous system
0.757 0.243 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.756 0.244 0.000
Y00-Y09 Assault
0.755 0.245 0.000
H74 Other disorders of middle ear and mastoid
0.752 0.248 0.000
T58 Toxic effect of carbon monoxide
0.750 0.250 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.750 0.250 0.000
Q61 Cystic kidney disease
0.749 0.251 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.748 0.252 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.748 0.252 0.000
F00 Dementia in Alzheimer's disease
0.747 0.253 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.747 0.253 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.744 0.255 0.000
X10-X19 Contact with heat and hot substances
0.744 0.256 0.000
T40.2 Other opioids
0.743 0.257 0.000
R27 Other lack of coordination
0.741 0.259 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.740 0.260 0.000
F34 Persistent mood [affective] disorders
0.739 0.261 0.000
Q50-Q56 Congenital malformations of genital organs
0.739 0.261 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.738 0.262 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.736 0.264 0.000
E26 Hyperaldosteronism
0.735 0.265 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.734 0.265 0.000
G30-G32 Other degenerative diseases of the nervous system
0.733 0.267 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.732 0.267 0.000
X50-X57 Overexertion, travel and privation
0.731 0.269 0.000
R07.2 Precordial pain
0.731 0.269 0.000
V40-V49 Car occupant injured in transport accident
0.730 0.270 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.730 0.270 0.000
V20-V29 Motorcycle rider injured in transport accident
0.729 0.271 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.728 0.272 0.000
E78.0 Pure hypercholesterolaemia
0.727 0.273 0.000
Q43 Other congenital malformations of intestine
0.727 0.273 0.000
M45-M49 Spondylopathies
0.724 0.276 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.724 0.276 0.000
S70-S79 Injuries to the hip and thigh
0.724 0.276 0.000
G54 Nerve root and plexus disorders
0.722 0.277 0.000
R40.2 Coma, unspecified
0.722 0.278 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.722 0.278 0.000
T93 Sequelae of injuries of lower limb
0.721 0.279 0.000
S91.3 Open wound of other parts of foot
0.720 0.280 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.720 0.280 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.718 0.282 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
T36 Poisoning by systemic antibiotics
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S19 Other and unspecified injuries of neck
0.714 0.286 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.286 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.711 0.289 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.711 0.289 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.711 0.289 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.711 0.289 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
R40.1 Stupor
0.709 0.291 0.000
J14 Pneumonia due to Haemophilus influenzae
0.709 0.291 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.709 0.291 0.000
T91 Sequelae of injuries of neck and trunk
0.708 0.292 0.000
Q80-Q89 Other congenital malformations
0.708 0.292 0.000
F17.9 Unspecified mental and behavioural disorder
0.708 0.292 0.000
F17.8 Other mental and behavioural disorders
0.708 0.292 0.000
F17.7 Residual and late-onset psychotic disorder
0.708 0.292 0.000
F17.6 Amnesic syndrome
0.708 0.292 0.000
F17.5 Psychotic disorder
0.708 0.292 0.000
F17.4 Withdrawal state with delirium
0.708 0.292 0.000
F17.3 Withdrawal state
0.708 0.292 0.000
F17.0 Acute intoxication
0.708 0.292 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.706 0.294 0.000
G70-G73 Diseases of myoneural junction and muscle
0.706 0.294 0.000
T98 Sequelae of other and unspecified effects of external causes
0.706 0.294 0.000
F32.1 Moderate depressive episode
0.706 0.294 0.000
V80-V89 Other land transport accidents
0.706 0.294 0.000
S60-S69 Injuries to the wrist and hand
0.706 0.294 0.000
T42.1 Iminostilbenes
0.705 0.295 0.000
J98 Other respiratory disorders
0.705 0.295 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.705 0.295 0.000
R45.8 Other symptoms and signs involving emotional state
0.705 0.295 0.000
E24 Cushing's syndrome
0.705 0.295 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.705 0.295 0.000
Y40 Systemic antibiotics
0.704 0.296 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.704 0.296 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.702 0.298 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.701 0.299 0.000
E73 Lactose intolerance
0.701 0.299 0.000
E84 Cystic fibrosis
0.700 0.300 0.000
E79 Disorders of purine and pyrimidine metabolism
0.700 0.300 0.000
E77 Disorders of glycoprotein metabolism
0.700 0.300 0.000
E76 Disorders of glycosaminoglycan metabolism
0.700 0.300 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.700 0.300 0.000
E74 Other disorders of carbohydrate metabolism
0.700 0.300 0.000
E72 Other disorders of amino-acid metabolism
0.700 0.300 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.700 0.300 0.000
E70 Disorders of aromatic amino-acid metabolism
0.700 0.300 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.700 0.300 0.000
E16.1 Other hypoglycaemia
0.700 0.300 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.697 0.303 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.697 0.303 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.695 0.305 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.695 0.305 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.695 0.305 0.000
T42.3 Barbiturates
0.695 0.305 0.000
T42.2 Succinimides and oxazolidinediones
0.695 0.305 0.000
T42.0 Hydantoin derivatives
0.695 0.305 0.000
S92.5 Fracture of other toe
0.695 0.305 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.695 0.305 0.000
S92.0 Fracture of calcaneus
0.695 0.305 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.694 0.305 0.000
Q35-Q37 Cleft lip and cleft palate
0.694 0.305 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.694 0.305 0.000
M95.0 Acquired deformity of nose
0.694 0.306 0.000
S14 Injury of nerves and spinal cord at neck level
0.694 0.306 0.000
R87 Abnormal findings in specimens from female genital organs
0.693 0.307 0.000
J43.9 Emphysema, unspecified
0.693 0.307 0.000
F38 Other mood [affective] disorders
0.692 0.308 0.000
F30 Manic episode
0.692 0.308 0.000
F39 Unspecified mood [affective] disorder
0.692 0.308 0.000
M86-M90 Other osteopathies
0.692 0.308 0.000
M54.1 Radiculopathy
0.692 0.308 0.000
F11.2 Dependence syndrome
0.690 0.310 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.689 0.311 0.000
T79-T79 Certain early complications of trauma
0.688 0.312 0.000
E34 Other endocrine disorders
0.688 0.312 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.688 0.312 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.688 0.312 0.000
R04.1 Haemorrhage from throat
0.688 0.312 0.000
S00-S09 Injuries to the head
0.687 0.313 0.000
T51 Toxic effect of alcohol
0.683 0.317 0.000
R46.2 Strange and inexplicable behaviour
0.682 0.318 0.000
E87.4 Mixed disorder of acid-base balance
0.682 0.318 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.681 0.319 0.000
R29.4 Clicking hip
0.680 0.320 0.000
R29.3 Abnormal posture
0.680 0.320 0.000
R29.2 Abnormal reflex
0.680 0.320 0.000
R29.1 Meningismus
0.680 0.320 0.000
R29.0 Tetany
0.680 0.320 0.000
R47-R49 Symptoms and signs involving speech and voice
0.679 0.321 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.678 0.322 0.000
E32 Diseases of thymus
0.678 0.322 0.000
E31 Polyglandular dysfunction
0.678 0.322 0.000
E30 Disorders of puberty, not elsewhere classified
0.678 0.322 0.000
E25 Adrenogenital disorders
0.678 0.322 0.000
E20 Hypoparathyroidism
0.678 0.322 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.677 0.323 0.000
J12 Viral pneumonia, not elsewhere classified
0.677 0.323 0.000
J09 Influenza due to certain identified influenza virus
0.677 0.323 0.000
R43 Disturbances of smell and taste
0.676 0.324 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.676 0.324 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.676 0.324 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.675 0.325 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.675 0.325 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.675 0.325 0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle
0.675 0.325 0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle
0.675 0.325 0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus
0.675 0.325 0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van
0.675 0.325 0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle
0.675 0.325 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.675 0.325 0.000
V10 Pedal cyclist injured in collision with pedestrian or animal
0.675 0.325 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.673 0.327 0.000
F17.2 Dependence syndrome
0.673 0.327 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.672 0.328 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.672 0.328 0.000
R45.4 Irritability and anger
0.671 0.329 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.671 0.329 0.000
S91.1 Open wound of toe(s) without damage to nail
0.671 0.329 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.671 0.329 0.000
H60-H62 Diseases of external ear
0.670 0.330 0.000
S56 Injury of muscle and tendon at forearm level
0.669 0.331 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.669 0.331 0.000
G36 Other acute disseminated demyelination
0.669 0.331 0.000
S99 Other and unspecified injuries of ankle and foot
0.669 0.331 0.000
S98 Traumatic amputation of ankle and foot
0.669 0.331 0.000
S97 Crushing injury of ankle and foot
0.669 0.331 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.669 0.331 0.000
S95 Injury of blood vessels at ankle and foot level
0.669 0.331 0.000
S94 Injury of nerves at ankle and foot level
0.669 0.331 0.000
Q00-Q07 Congenital malformations of the nervous system
0.668 0.332 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.668 0.332 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.667 0.332 0.000
G52 Disorders of other cranial nerves
0.667 0.332 0.000
E15 Nondiabetic hypoglycaemic coma
0.667 0.333 0.000
T90 Sequelae of injuries of head
0.667 0.333 0.000
E55 Vitamin D deficiency
0.666 0.334 0.000
F03 Unspecified dementia
0.666 0.334 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.663 0.336 0.000
T75 Effects of other external causes
0.663 0.336 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.663 0.337 0.000
Q61.3 Polycystic kidney, unspecified
0.662 0.338 0.000
R45.2 Unhappiness
0.661 0.339 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.661 0.339 0.000
T39.4 Antirheumatics, not elsewhere classified
0.661 0.339 0.000
T39.2 Pyrazolone derivatives
0.661 0.339 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.661 0.339 0.000
E22.1 Hyperprolactinaemia
0.660 0.340 0.000
Q63 Other congenital malformations of kidney
0.658 0.341 0.000
M91-M94 Chondropathies
0.658 0.342 0.000
X23 Contact with hornets, wasps and bees
0.658 0.342 0.000
S11 Open wound of neck
0.657 0.342 0.000
F31.8 Other bipolar affective disorders
0.657 0.342 0.000
F31.7 Bipolar affective disorder, currently in remission
0.657 0.342 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.657 0.342 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.657 0.342 0.000
M40-M43 Deforming dorsopathies
0.657 0.343 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.657 0.343 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.657 0.343 0.000
E29 Testicular dysfunction
0.656 0.344 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.656 0.344 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.655 0.345 0.000
Y88 Sequelae of surgical and medical care as external cause
0.655 0.345 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.655 0.345 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.654 0.346 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.654 0.346 0.000
S92.3 Fracture of metatarsal bone
0.653 0.347 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.653 0.347 0.000
H69 Other disorders of Eustachian tube
0.652 0.348 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.652 0.348 0.000
G57.6 Lesion of plantar nerve
0.652 0.348 0.000
R02 Gangrene, not elsewhere classified
0.651 0.349 0.000
Q18 Other congenital malformations of face and neck
0.651 0.349 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.651 0.349 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.650 0.349 0.000
G00 Bacterial meningitis, not elsewhere classified
0.650 0.350 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.650 0.350 0.000
V18.4 Driver injured in traffic accident
0.650 0.350 0.000
V18.5 Passenger injured in traffic accident
0.650 0.350 0.000
V18.3 Person injured while boarding or alighting
0.650 0.350 0.000
V18.1 Passenger injured in nontraffic accident
0.650 0.350 0.000
E22.0 Acromegaly and pituitary gigantism
0.649 0.351 0.000
Y86 Sequelae of other accidents
0.647 0.353 0.000
E28.2 Polycystic ovarian syndrome
0.646 0.354 0.000
S51 Open wound of forearm
0.645 0.355 0.000
T18 Foreign body in alimentary tract
0.644 0.355 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.644 0.356 0.000
J11 Influenza, virus not identified
0.643 0.357 0.000
R40.0 Somnolence
0.643 0.357 0.000
U89 Agent resistant to other and unspecified antibiotics
0.642 0.358 0.000
E65-E68 Obesity and other hyperalimentation
0.641 0.359 0.000
T92 Sequelae of injuries of upper limb
0.641 0.359 0.000
X78 Intentional self-harm by sharp object
0.641 0.359 0.000
X48 Accidental poisoning by and exposure to pesticides
0.641 0.359 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.641 0.359 0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.641 0.359 0.000
X45 Accidental poisoning by and exposure to alcohol
0.641 0.359 0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.641 0.359 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.641 0.359 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.641 0.359 0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.641 0.359 0.000
M60-M63 Disorders of muscles
0.640 0.360 0.000
F60 Specific personality disorders
0.639 0.361 0.000
S92.2 Fracture of other tarsal bone(s)
0.639 0.361 0.000
M54.55 Low back pain (Thoracolumbar region)
0.639 0.361 0.000
T95 Sequelae of burns, corrosions and frostbite
0.638 0.362 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.638 0.362 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.638 0.362 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.638 0.362 0.000
M48 Other spondylopathies
0.638 0.362 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.637 0.363 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.637 0.363 0.000
E63 Other nutritional deficiencies
0.637 0.363 0.000
E56 Other vitamin deficiencies
0.637 0.363 0.000
E51 Thiamine deficiency
0.637 0.363 0.000
E50 Vitamin A deficiency
0.637 0.363 0.000
E60 Dietary zinc deficiency
0.637 0.363 0.000
E59 Dietary selenium deficiency
0.637 0.363 0.000
E58 Dietary calcium deficiency
0.637 0.363 0.000
E54 Ascorbic acid deficiency
0.637 0.363 0.000
E52 Niacin deficiency [pellagra]
0.637 0.363 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.636 0.364 0.000
T46.1 Calcium-channel blockers
0.635 0.364 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.635 0.365 0.000
J18.0 Bronchopneumonia, unspecified
0.634 0.366 0.000
M54.8 Other dorsalgia
0.634 0.366 0.000
M54.0 Panniculitis affecting regions of neck and back
0.634 0.366 0.000
Q43.8 Other specified congenital malformations of intestine
0.633 0.367 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.633 0.367 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.633 0.367 0.000
E16.4 Abnormal secretion of gastrin
0.633 0.367 0.000
E16.3 Increased secretion of glucagon
0.633 0.367 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.632 0.368 0.000
E85.9 Amyloidosis, unspecified
0.631 0.369 0.000
H74.4 Polyp of middle ear
0.631 0.369 0.000
S20-S29 Injuries to the thorax
0.629 0.371 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.628 0.372 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.628 0.372 0.000
H73 Other disorders of tympanic membrane
0.627 0.373 0.000
T40.6 Other and unspecified narcotics
0.627 0.373 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.627 0.373 0.000
Q17 Other congenital malformations of ear
0.626 0.374 0.000
S17 Crushing injury of neck
0.625 0.375 0.000
S15 Injury of blood vessels at neck level
0.625 0.375 0.000
S12 Fracture of neck
0.625 0.375 0.000
S18 Traumatic amputation at neck level
0.625 0.375 0.000
S16 Injury of muscle and tendon at neck level
0.625 0.375 0.000
R87.6 Abnormal cytological findings
0.625 0.375 0.000
R27.0 Ataxia, unspecified
0.624 0.376 0.000
Y40.8 Other systemic antibiotics
0.623 0.377 0.000
E40-E46 Malnutrition
0.623 0.377 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.623 0.377 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.623 0.377 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.622 0.378 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.622 0.378 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.622 0.378 0.000
G23 Other degenerative diseases of basal ganglia
0.621 0.379 0.000
G21 Secondary Parkinsonism
0.621 0.379 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.621 0.379 0.000
G22 Parkinsonism in diseases classified elsewhere
0.621 0.379 0.000
E86 Volume depletion
0.621 0.379 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.620 0.379 0.000
E23 Hypofunction and other disorders of pituitary gland
0.620 0.380 0.000
S62 Fracture at wrist and hand level
0.620 0.380 0.000
F80-F89 Disorders of psychological development
0.620 0.380 0.000
T65 Toxic effect of other and unspecified substances
0.620 0.380 0.000
T62 Toxic effect of other noxious substances eaten as food
0.620 0.380 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.620 0.380 0.000
T60 Toxic effect of pesticides
0.620 0.380 0.000
T57 Toxic effect of other inorganic substances
0.620 0.380 0.000
T56 Toxic effect of metals
0.620 0.380 0.000
T54 Toxic effect of corrosive substances
0.620 0.380 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.620 0.380 0.000
T52 Toxic effect of organic solvents
0.620 0.380 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.620 0.380 0.000
T55 Toxic effect of soaps and detergents
0.620 0.380 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.620 0.380 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.619 0.381 0.000
T63 Toxic effect of contact with venomous animals
0.619 0.381 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.617 0.383 0.000
E27.8 Other specified disorders of adrenal gland
0.617 0.383 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.617 0.383 0.000
Q76 Congenital malformations of spine and bony thorax
0.617 0.383 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.616 0.384 0.000
H80-H83 Diseases of inner ear
0.616 0.384 0.000
G30 Alzheimer's disease
0.616 0.384 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.616 0.384 0.000
E87.0 Hyperosmolality and hypernatraemia
0.615 0.385 0.000
M50 Cervical disk disorders
0.614 0.386 0.000
Y89 Sequelae of other external causes
0.614 0.386 0.000
G25 Other extrapyramidal and movement disorders
0.614 0.386 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.614 0.386 0.000
F02 Dementia in other diseases classified elsewhere
0.614 0.386 0.000
F09 Unspecified organic or symptomatic mental disorder
0.614 0.386 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.614 0.386 0.000
M00-M03 Infectious arthropathies
0.613 0.387 0.000
M54.54 Low back pain-Thoracic
0.612 0.387 0.000
M54.53 Low back pain-Cervicothoracic
0.612 0.387 0.000
M54.52 Low back pain-Cervical
0.612 0.387 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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