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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7974772
log Bayes Factor = 6.73048
Chromosome 12   position 112,332,283  (GRCh37) Explore rs7974772 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.001 0.999
I21 Acute myocardial infarction
0.000 0.002 0.998
E03.9 Hypothyroidism, unspecified
0.000 0.002 0.998
I25 Chronic ischaemic heart disease
0.000 0.002 0.998
I20-I25 Ischaemic heart diseases
0.000 0.002 0.998
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.011 0.989
I25.1 Atherosclerotic heart disease
0.000 0.014 0.986
I25.5 Ischaemic cardiomyopathy
0.000 0.064 0.936
I22 Subsequent myocardial infarction
0.000 0.065 0.935
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.100 0.900
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.152 0.848
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.154 0.846
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.156 0.844
I21.9 Acute myocardial infarction, unspecified
0.000 0.170 0.830
I24 Other acute ischaemic heart diseases
0.000 0.170 0.830
Z95.0 Presence of cardiac pacemaker
0.000 0.196 0.804
I25.2 Old myocardial infarction
0.000 0.210 0.790
Z95.4 Presence of other heart-valve replacement
0.000 0.212 0.788
I25.4 Coronary artery aneurysm
0.000 0.230 0.770
I24.8 Other forms of acute ischaemic heart disease
0.000 0.231 0.769
Z95.1 Presence of aortocoronary bypass graft
0.000 0.237 0.763
Z95.3 Presence of xenogenic heart valve
0.000 0.248 0.752
Z95.2 Presence of prosthetic heart valve
0.000 0.273 0.727
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.282 0.718
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.284 0.716
I25.6 Silent myocardial ischaemia
0.000 0.284 0.715
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.297 0.703
I23 Certain current complications following acute myocardial infarction
0.000 0.314 0.685
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.339 0.661
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.348 0.652
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.353 0.647
I24.1 Dressler's syndrome
0.000 0.378 0.622
I25.3 Aneurysm of heart
0.000 0.379 0.620
E03 Other hypothyroidism
0.000 0.384 0.616
I22.8 Subsequent myocardial infarction of other sites
0.000 0.392 0.608
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.399 0.601
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.456 0.544
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.468 0.532
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.499 0.501
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.508 0.491
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.508 0.491
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.508 0.491
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.508 0.491
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.508 0.491
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.508 0.491
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.508 0.491
I23.8 Other current complications following acute myocardial infarction
0.000 0.538 0.462
I21.4 Acute subendocardial myocardial infarction
0.000 0.542 0.458
E03.5 Myxoedema coma
0.000 0.558 0.442
E03.4 Atrophy of thyroid (acquired)
0.000 0.558 0.442
E03.3 Postinfectious hypothyroidism
0.000 0.558 0.442
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.558 0.442
E03.8 Other specified hypothyroidism
0.000 0.572 0.428
E03.1 Congenital hypothyroidism without goitre
0.000 0.589 0.410
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.703 0.297
E00-E07 Disorders of thyroid gland
0.000 0.710 0.290
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.720 0.280
E05.9 Thyrotoxicosis, unspecified
0.000 0.723 0.277
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.770 0.230
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.792 0.208
E00 Congenital iodine-deficiency syndrome
0.000 0.792 0.208
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.794 0.206
E05.5 Thyroid crisis or storm
0.000 0.799 0.201
E05.4 Thyrotoxicosis factitia
0.000 0.799 0.201
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.799 0.201
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.799 0.201
E05.8 Other thyrotoxicosis
0.000 0.813 0.187
E06 Thyroiditis
0.000 0.815 0.184
I24.9 Acute ischaemic heart disease, unspecified
0.001 0.837 0.162
E07 Other disorders of thyroid
0.000 0.839 0.161
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.851 0.149
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.851 0.149
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.851 0.149
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.851 0.149
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.851 0.149
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.851 0.149
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.851 0.149
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.851 0.149
I20 Angina pectoris
0.000 0.865 0.135
E06.4 Drug-induced thyroiditis
0.000 0.867 0.132
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.867 0.132
E06.1 Subacute thyroiditis
0.000 0.867 0.132
E06.0 Acute thyroiditis
0.000 0.867 0.132
E06.9 Thyroiditis, unspecified
0.000 0.869 0.131
E06.3 Autoimmune thyroiditis
0.000 0.872 0.128
E06.5 Other chronic thyroiditis
0.000 0.883 0.117
E07.1 Dyshormogenetic goitre
0.000 0.884 0.116
E07.0 Hypersecretion of calcitonin
0.000 0.884 0.116
I20.8 Other forms of angina pectoris
0.000 0.884 0.116
E07.8 Other specified disorders of thyroid
0.000 0.891 0.109
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.893 0.106
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.906 0.094
E07.9 Disorder of thyroid, unspecified
0.000 0.919 0.081
I10 Essential (primary) hypertension
0.000 0.919 0.081
Chapter IX Diseases of the circulatory system
0.000 0.920 0.080
I10-I15 Hypertensive diseases
0.000 0.924 0.076
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.928 0.072
I99 Other and unspecified disorders of circulatory system
0.000 0.933 0.067
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.938 0.062
J34.2 Deviated nasal septum
0.059 0.941 0.000
I00-I02 Acute rheumatic fever
0.000 0.942 0.058
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.943 0.057
I13 Hypertensive heart and renal disease
0.000 0.945 0.055
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.946 0.054
I15 Secondary hypertension
0.000 0.949 0.051
I49.9 Cardiac arrhythmia, unspecified
0.000 0.950 0.050
I49.3 Ventricular premature depolarisation
0.000 0.950 0.050
I30-I52 Other forms of heart disease
0.000 0.950 0.050
I49 Other cardiac arrhythmias
0.000 0.950 0.050
I97.1 Other functional disturbances following cardiac surgery
0.000 0.951 0.049
I47.2 Ventricular tachycardia
0.000 0.951 0.049
I47 Paroxysmal tachycardia
0.000 0.952 0.048
I35 Nonrheumatic aortic valve disorders
0.000 0.953 0.047
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.953 0.047
I50 Heart failure
0.000 0.953 0.047
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.955 0.044
I97.0 Postcardiotomy syndrome
0.000 0.955 0.044
I35.0 Aortic (valve) stenosis
0.000 0.956 0.044
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.957 0.043
I42 Cardiomyopathy
0.000 0.958 0.042
I02 Rheumatic chorea
0.000 0.958 0.041
I01 Rheumatic fever with heart involvement
0.000 0.958 0.041
I00 Rheumatic fever without mention of heart involvement
0.000 0.958 0.041
I50.1 Left ventricular failure
0.000 0.959 0.041
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.959 0.041
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.959 0.041
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.959 0.041
I98.0 Cardiovascular syphilis
0.000 0.959 0.041
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.959 0.041
E04 Other non-toxic goitre
0.000 0.959 0.041
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.960 0.039
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.960 0.039
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.960 0.039
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.960 0.039
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.960 0.040
I85 Oesophageal varices
0.000 0.961 0.039
I85.0 Oesophageal varices with bleeding
0.000 0.962 0.038
I49.0 Ventricular fibrillation and flutter
0.000 0.962 0.038
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.962 0.038
I36 Nonrheumatic tricuspid valve disorders
0.000 0.962 0.038
I80 Phlebitis and thrombophlebitis
0.000 0.962 0.038
I50.9 Heart failure, unspecified
0.000 0.963 0.037
I11 Hypertensive heart disease
0.000 0.963 0.037
I15.8 Other secondary hypertension
0.000 0.963 0.037
I15.2 Hypertension secondary to endocrine disorders
0.000 0.963 0.037
I15.0 Renovascular hypertension
0.000 0.963 0.037
I50.0 Congestive heart failure
0.000 0.963 0.037
I49.4 Other and unspecified premature depolarisation
0.000 0.963 0.037
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.963 0.037
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.963 0.037
I33 Acute and subacute endocarditis
0.000 0.964 0.036
I52 Other heart disorders in diseases classified elsewhere
0.000 0.964 0.036
I48 Atrial fibrillation and flutter
0.000 0.964 0.036
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.964 0.036
I41 Myocarditis in diseases classified elsewhere
0.000 0.964 0.036
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.964 0.036
I32 Pericarditis in diseases classified elsewhere
0.000 0.964 0.036
I49.2 Junctional premature depolarisation
0.000 0.964 0.036
I42.0 Dilated cardiomyopathy
0.000 0.964 0.036
I86 Varicose veins of other sites
0.000 0.964 0.036
I86.4 Gastric varices
0.000 0.964 0.036
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.965 0.035
I15.9 Seconday hypertension, unspecified
0.000 0.965 0.035
I37 Pulmonary valve disorders
0.000 0.965 0.035
I35.9 Aortic valve disorder, unspecified
0.000 0.965 0.035
I15.1 Hypertension secondary to other renal disorders
0.000 0.965 0.034
I42.9 Cardiomyopathy, unspecified
0.000 0.966 0.034
I40 Acute myocarditis
0.000 0.967 0.033
I47.0 Reentry ventricular arrhythmia
0.000 0.967 0.033
I42.5 Other restrictive cardiomyopathy
0.000 0.970 0.030
I42.4 Endocardial fibroelastosis
0.000 0.970 0.030
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.970 0.030
I05-I09 Chronic rheumatic heart diseases
0.000 0.970 0.030
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.970 0.030
I01.8 Other acute rheumatic heart disease
0.000 0.970 0.030
I01.2 Acute rheumatic myocarditis
0.000 0.970 0.030
I01.1 Acute rheumatic endocarditis
0.000 0.970 0.030
I01.0 Acute rheumatic pericarditis
0.000 0.970 0.030
I02.9 Rheumatic chorea without heart involvement
0.000 0.970 0.030
I02.0 Rheumatic chorea with heart involvement
0.000 0.970 0.030
R25 Abnormal involuntary movements
0.030 0.970 0.000
R25.1 Tremor, unspecified
0.030 0.970 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.970 0.030
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.970 0.030
R25.2 Cramp and spasm
0.029 0.971 0.000
E04.8 Other specified non-toxic goitre
0.000 0.971 0.029
I42.2 Other hypertrophic cardiomyopathy
0.000 0.971 0.029
I85.9 Oesophageal varices without bleeding
0.000 0.971 0.029
I12 Hypertensive renal disease
0.000 0.971 0.029
I42.6 Alcoholic cardiomyopathy
0.000 0.972 0.028
I49.5 Sick sinus syndrome
0.000 0.972 0.028
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.972 0.028
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.972 0.028
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.972 0.028
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.972 0.028
I30 Acute pericarditis
0.000 0.972 0.027
E04.0 Non-toxic diffuse goitre
0.000 0.973 0.027
I86.2 Pelvic varices
0.000 0.973 0.026
I82 Other venous embolism and thrombosis
0.000 0.973 0.026
I33.0 Acute and subacute infective endocarditis
0.000 0.974 0.026
I33.9 Acute endocarditis, unspecified
0.000 0.974 0.026
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.026 0.974 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.974 0.026
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.974 0.026
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.974 0.026
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.974 0.026
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.974 0.026
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.974 0.026
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.974 0.026
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.974 0.026
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.974 0.026
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.974 0.026
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.974 0.026
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.974 0.026
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.974 0.026
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.974 0.026
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.974 0.026
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.974 0.026
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.974 0.026
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.974 0.026
I48.4 Atypical atrial flutter
0.000 0.974 0.026
I48.3 Typical atrial flutter
0.000 0.974 0.026
I48.2 Chronic atrial fibrillation
0.000 0.974 0.026
I48.1 Persistent atrial fibrillation
0.000 0.974 0.026
I48.0 Paroxysmal atrial fibrillation
0.000 0.974 0.026
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.974 0.026
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.974 0.026
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.974 0.026
I86.3 Vulval varices
0.000 0.974 0.026
I86.0 Sublingual varices
0.000 0.974 0.026
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.974 0.026
I37.9 Pulmonary valve disorder, unspecified
0.000 0.975 0.025
I37.8 Other pulmonary valve disorders
0.000 0.975 0.025
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.975 0.025
I37.0 Pulmonary valve stenosis
0.000 0.975 0.025
I88 Nonspecific lymphadenitis
0.000 0.975 0.025
I35.1 Aortic (valve) insufficiency
0.000 0.975 0.025
I20.1 Angina pectoris with documented spasm
0.002 0.976 0.022
I37.1 Pulmonary valve insufficiency
0.000 0.976 0.024
R26 Abnormalities of gait and mobility
0.024 0.976 0.000
I35.8 Other aortic valve disorders
0.000 0.976 0.024
I40.9 Acute myocarditis, unspecified
0.000 0.976 0.024
I40.8 Other acute myocarditis
0.000 0.976 0.024
I40.1 Isolated myocarditis
0.000 0.976 0.024
I83 Varicose veins of lower extremities
0.000 0.976 0.024
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.976 0.023
R25.8 Other and unspecified abnormal involuntary movements
0.023 0.976 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.977 0.023
R26.3 Immobility
0.023 0.977 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.977 0.022
I07 Rheumatic tricuspid valve diseases
0.000 0.977 0.023
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.022 0.978 0.000
I42.8 Other cardiomyopathies
0.000 0.978 0.022
R27 Other lack of coordination
0.022 0.978 0.000
I06 Rheumatic aortic valve diseases
0.000 0.978 0.022
R25.0 Abnormal head movements
0.022 0.978 0.000
I38 Endocarditis, valve unspecified
0.000 0.979 0.021
I87 Other disorders of veins
0.000 0.979 0.021
I40.0 Infective myocarditis
0.000 0.979 0.020
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.979 0.021
I26 Pulmonary embolism
0.000 0.980 0.020
I49.1 Atrial premature depolarisation
0.000 0.980 0.020
R26.8 Other and unspecified abnormalities of gait and mobility
0.020 0.980 0.000
I30.1 Infective pericarditis
0.000 0.980 0.020
E04.9 Non-toxic goitre, unspecified
0.000 0.980 0.020
I30.8 Other forms of acute pericarditis
0.000 0.980 0.020
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.980 0.020
I28 Other diseases of pulmonary vessels
0.000 0.980 0.020
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.020 0.980 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.981 0.019
I86.1 Scrotal varices
0.000 0.981 0.019
I82.3 Embolism and thrombosis of renal vein
0.000 0.981 0.019
I82.1 Thrombophlebitis migrans
0.000 0.981 0.019
I82.0 Budd-Chiari syndrome
0.000 0.981 0.019
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.981 0.019
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.981 0.019
I09 Other rheumatic heart diseases
0.000 0.981 0.018
R25.3 Fasciculation
0.018 0.981 0.000
R27.8 Other and unspecified lack of coordination
0.019 0.981 0.000
I88.8 Other nonspecific lymphadenitis
0.000 0.982 0.018
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.982 0.018
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.982 0.018
I12.9 Hypertensive renal disease without renal failure
0.000 0.982 0.018
R29.0 Tetany
0.018 0.982 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.982 0.018
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.982 0.018
I45 Other conduction disorders
0.000 0.982 0.018
I81 Portal vein thrombosis
0.000 0.982 0.018
I86.8 Varicose veins of other specified sites
0.000 0.982 0.017
R26.1 Paralytic gait
0.017 0.982 0.000
I07.1 Tricuspid insufficiency
0.000 0.982 0.017
R29.2 Abnormal reflex
0.017 0.982 0.000
I82.2 Embolism and thrombosis of vena cava
0.000 0.983 0.017
T93.2 Sequelae of other fractures of lower limb
0.017 0.983 0.000
I87.8 Other specified disorders of veins
0.000 0.983 0.017
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.983 0.017
R27.0 Ataxia, unspecified
0.017 0.983 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.983 0.017
I07.9 Tricuspid valve disease, unspecified
0.000 0.983 0.016
I07.8 Other tricuspid valve diseases
0.000 0.983 0.016
I07.2 Tricuspid stenosis with insufficiency
0.000 0.983 0.016
I07.0 Tricuspid stenosis
0.000 0.983 0.016
I44 Atrioventricular and left bundle-branch block
0.000 0.984 0.016
R29.4 Clicking hip
0.016 0.984 0.000
R29.3 Abnormal posture
0.016 0.984 0.000
R29.1 Meningismus
0.016 0.984 0.000
I82.8 Embolism and thrombosis of other specified veins
0.000 0.984 0.016
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.984 0.016
R26.0 Ataxic gait
0.016 0.984 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.984 0.016
I06.8 Other rheumatic aortic valve diseases
0.000 0.984 0.016
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.984 0.016
I06.1 Rheumatic aortic insufficiency
0.000 0.984 0.016
I06.0 Rheumatic aortic stenosis
0.000 0.984 0.016
I73 Other peripheral vascular diseases
0.000 0.984 0.016
I08 Multiple valve diseases
0.000 0.984 0.016
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.016 0.984 0.000
I31 Other diseases of pericardium
0.000 0.984 0.016
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.984 0.015
S66 Injury of muscle and tendon at wrist and hand level
0.016 0.984 0.000
I87.9 Disorder of vein, unspecified
0.000 0.985 0.015
I87.0 Postphlebitic syndrome
0.000 0.985 0.015
J34 Other disorders of nose and nasal sinuses
0.015 0.985 0.000
I78 Diseases of capillaries
0.000 0.985 0.015
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.015 0.985 0.000
I46 Cardiac arrest
0.000 0.985 0.015
S22.40 Multiple fractures of ribs (closed)
0.015 0.985 0.000
I45.4 Nonspecific intraventricular block
0.000 0.985 0.015
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.985 0.014
I28.1 Aneurysm of pulmonary artery
0.000 0.985 0.014
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.985 0.014
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.985 0.014
S22.4 Multiple fractures of ribs
0.014 0.986 0.000
J34.3 Hypertrophy of nasal turbinates
0.014 0.986 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.014 0.986 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.014 0.986 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.014 0.986 0.000
I45.6 Preexcitation syndrome
0.000 0.986 0.014
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.986 0.014
I45.9 Conduction disorder, unspecified
0.000 0.986 0.014
T43.2 Other and unspecified antidepressants
0.014 0.986 0.000
I73.0 Raynaud's syndrome
0.000 0.986 0.014
I09.8 Other specified rheumatic heart diseases
0.000 0.986 0.013
I09.2 Chronic rheumatic pericarditis
0.000 0.986 0.013
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.986 0.013
I09.0 Rheumatic myocarditis
0.000 0.986 0.013
I45.2 Bifascicular block
0.000 0.986 0.014
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.986 0.013
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.013 0.987 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.013 0.987 0.000
I44.7 Left bundle-branch block, unspecified
0.000 0.987 0.013
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.987 0.013
I45.0 Right fascicular block
0.000 0.987 0.013
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.987 0.013
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.987 0.013
S22.0 Fracture of thoracic vertebra
0.013 0.987 0.000
I05 Rheumatic mitral valve diseases
0.000 0.987 0.013
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.013 0.987 0.000
S27.0 Traumatic pneumothorax
0.013 0.987 0.000
I28.8 Other specified diseases of pulmonary vessels
0.000 0.987 0.012
S20-S29 Injuries to the thorax
0.013 0.987 0.000
S27 Injury of other and unspecified intrathoracic organs
0.013 0.987 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.987 0.012
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.012 0.988 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.012 0.988 0.000
I73.8 Other specified peripheral vascular diseases
0.000 0.988 0.012
I08.0 Disorders of both mitral and aortic valves
0.000 0.988 0.012
S32.00 Fracture of lumbar vertebra (closed)
0.012 0.988 0.000
I20.9 Angina pectoris, unspecified
0.000 0.988 0.012
I89.1 Lymphangitis
0.000 0.988 0.012
I45.5 Other specified heart block
0.000 0.988 0.012
I44.5 Left posterior fascicular block
0.000 0.988 0.012
I44.4 Left anterior fascicular block
0.000 0.988 0.012
S32 Fracture of lumbar spine and pelvis
0.012 0.988 0.000
S32.0 Fracture of lumbar vertebra
0.012 0.988 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.000 0.988 0.012
I73.9 Peripheral vascular disease, unspecified
0.000 0.988 0.012
I44.3 Other and unspecified atrioventricular block
0.000 0.988 0.012
I44.6 Other and unspecified fascicular block
0.000 0.988 0.012
I78.8 Other diseases of capillaries
0.000 0.988 0.012
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.988 0.012
I08.9 Multiple valve disease, unspecified
0.000 0.988 0.012
S61.9 Open wound of wrist and hand, part unspecified
0.012 0.988 0.000
R29.6 Tendency to fall, not elsewhere classified
0.012 0.988 0.000
I31.8 Other specified diseases of pericardium
0.000 0.989 0.011
I31.2 Haemopericardium, not elsewhere classified
0.000 0.989 0.011
I31.1 Chronic constrictive pericarditis
0.000 0.989 0.011
I31.0 Chronic adhesive pericarditis
0.000 0.989 0.011
I45.8 Other specified conduction disorders
0.000 0.989 0.011
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.011 0.989 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.011 0.989 0.000
S60-S69 Injuries to the wrist and hand
0.011 0.989 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.989 0.011
I78.9 Disease of capillaries, unspecified
0.000 0.989 0.011
S22.1 Multiple fractures of thoracic spine
0.011 0.989 0.000
I30.9 Acute pericarditis, unspecified
0.000 0.989 0.011
I46.1 Sudden cardiac death, so described
0.000 0.989 0.011
T43.4 Butyrophenone and thioxanthene neuroleptics
0.011 0.989 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.989 0.011
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.989 0.011
I95 Hypotension
0.000 0.989 0.011
T43.0 Tricyclic and tetracyclic antidepressants
0.011 0.989 0.000
S22.5 Flail chest
0.011 0.989 0.000
I74 Arterial embolism and thrombosis
0.000 0.989 0.011
S32.4 Fracture of acetabulum
0.011 0.989 0.000
S22.41 Multiple fractures of ribs (open)
0.010 0.989 0.000
S72.30 Fracture of shaft of femur (closed)
0.000 0.990 0.010
T43.3 Phenothiazine antipsychotics and neuroleptics
0.010 0.990 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.010 0.990 0.000
S27.2 Traumatic heamopneumothorax
0.010 0.990 0.000
S65 Injury of blood vessels at wrist and hand level
0.010 0.990 0.000
S22.9 Fracture of bony thorax, part unspecified
0.010 0.990 0.000
S22.8 Fracture of other parts of bony thorax
0.010 0.990 0.000
I09.9 Rheumatic heart disease, unspecified
0.000 0.990 0.010
S22.3 Fracture of rib
0.010 0.990 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.010 0.990 0.000
T92 Sequelae of injuries of upper limb
0.010 0.990 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.990 0.010
S64 Injury of nerves at wrist and hand level
0.010 0.990 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.010 0.990 0.000
S32.40 Fracture of acetabulum (closed)
0.010 0.990 0.000
S61 Open wound of wrist and hand
0.010 0.990 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.010 0.990 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.010 0.990 0.000
I05.2 Mitral stenosis with insufficiency
0.000 0.990 0.009
I49.8 Other specified cardiac arrhythmias
0.001 0.990 0.009
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.010 0.990 0.000
S72.3 Fracture of shaft of femur
0.000 0.990 0.009
S22.01 Fracture of thoracic vertebra (open)
0.009 0.990 0.000
I05.8 Other mitral valve diseases
0.000 0.990 0.009
S69 Other and unspecified injuries of wrist and hand
0.010 0.990 0.000
I08.8 Other multiple valve diseases
0.000 0.990 0.009
J34.1 Cyst and mucocele of nose and nasal sinus
0.009 0.990 0.000
S27.3 Other injuries of lung
0.009 0.990 0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)
0.009 0.990 0.000
S36 Injury of intra-abdominal organs
0.009 0.991 0.000
I44.2 Atrioventricular block, complete
0.000 0.991 0.009
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.009 0.991 0.000
S26 Injury of heart
0.009 0.991 0.000
S25 Injury of blood vessels of thorax
0.009 0.991 0.000
S24 Injury of nerves and spinal cord at thorax level
0.009 0.991 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.009 0.991 0.000
S27.9 Injury of unspecified intrathoracic organ
0.009 0.991 0.000
S27.8 Injury of other specified intrathoracic organs
0.009 0.991 0.000
S27.7 Multiple injuries of intrathoracic organs
0.009 0.991 0.000
S27.6 Injury of pleura
0.009 0.991 0.000
S27.5 Injury of thoracic trachea
0.009 0.991 0.000
S27.4 Injury of bronchus
0.009 0.991 0.000
I78.1 Naevus, nonneoplastic
0.000 0.991 0.009
I72 Other aneurysm
0.000 0.991 0.009
I79.1 Aortitis in diseases classified elsewhere
0.000 0.991 0.009
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.991 0.009
T92.1 Sequelae of fracture of arm
0.009 0.991 0.000
S72 Fracture of femur
0.001 0.991 0.009
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.991 0.009
S65.5 Injury of blood vessel(s) of other finger
0.009 0.991 0.000
T92.0 Sequelae of open wound of upper limb
0.009 0.991 0.000
S21 Open wound of thorax
0.009 0.991 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.991 0.009
T43.9 Psychotropic drug, unspecified
0.009 0.991 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.009 0.991 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.009 0.991 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.009 0.991 0.000
T93 Sequelae of injuries of lower limb
0.009 0.991 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.009 0.991 0.000
I70 Atherosclerosis
0.000 0.991 0.009
S32.3 Fracture of ilium
0.009 0.991 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.009 0.991 0.000
S32.1 Fracture of sacrum
0.009 0.991 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.009 0.991 0.000
T31 Burns classified according to extent of body surface involved
0.009 0.991 0.000
S22.2 Fracture of sternum
0.009 0.991 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.991 0.009
S22.10 Multiple fractures of thoracic spine (closed)
0.009 0.991 0.000
I87.1 Compression of vein
0.000 0.991 0.009
S64.0 Injury of ulnar nerve at wrist and hand level
0.009 0.991 0.000
S32.2 Fracture of coccyx
0.009 0.991 0.000
S32.01 Fracture of lumbar vertebra (open)
0.009 0.991 0.000
S72.0 Fracture of neck of femur
0.000 0.991 0.009
S72.00 Fracture of neck of femur (closed)
0.000 0.991 0.009
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.009 0.991 0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)
0.009 0.991 0.000
I05.0 Mitral stenosis
0.000 0.991 0.009
T92.8 Sequelae of other specified injuries of upper limb
0.009 0.991 0.000
S72.1 Pertrochanteric fracture
0.000 0.991 0.008
T40.2 Other opioids
0.009 0.991 0.000
S65.0 Injury of ulnar artery at wrist and hand level
0.009 0.991 0.000
S10-S19 Injuries to the neck
0.009 0.991 0.000
S32.5 Fracture of pubis
0.009 0.991 0.000
S29 Other and unspecified injuries of thorax
0.009 0.991 0.000
T31.0 Burns involving less than 10% of body surface
0.009 0.991 0.000
I77 Other disorders of arteries and arterioles
0.000 0.991 0.009
S72.10 Pertrochanteric fracture (closed)
0.000 0.991 0.009
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.991 0.009
I05.1 Rheumatic mitral insufficiency
0.000 0.991 0.008
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.991 0.008
T36-T50 Poisoning by drugs, medicaments and biological substances
0.008 0.992 0.000
S10 Superficial injury of neck
0.008 0.992 0.000
T98 Sequelae of other and unspecified effects of external causes
0.008 0.992 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.008 0.992 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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