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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs8007689
log Bayes Factor = 21.599
Chromosome 14   position 101,417,662  (GRCh37) Explore rs8007689 on Ensembl!
Variant rs8007689 is part of Cluster X0152

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
M45-M49 Spondylopathies
0.998 0.002 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.997 0.003 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.996 0.004 0.000
Chapter V Mental and behavioural disorders
0.996 0.004 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.994 0.006 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
S00-S09 Injuries to the head
0.990 0.010 0.000
M50-M54 Other dorsopathies
0.988 0.012 0.000
Chapter X Diseases of the respiratory system
0.988 0.012 0.000
Chapter IX Diseases of the circulatory system
0.988 0.012 0.000
M47 Spondylosis
0.981 0.019 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.981 0.019 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.981 0.019 0.000
M54 Dorsalgia
0.981 0.019 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.980 0.020 0.000
R94 Abnormal results of function studies
0.980 0.020 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.978 0.022 0.000
J40-J47 Chronic lower respiratory diseases
0.977 0.023 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.974 0.026 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.974 0.026 0.000
Z85 Personal history of malignant neoplasm
0.970 0.030 0.000
J44 Other chronic obstructive pulmonary disease
0.965 0.035 0.000
R94.5 Abnormal results of liver function studies
0.963 0.037 0.000
I60-I69 Cerebrovascular diseases
0.960 0.040 0.000
I30-I52 Other forms of heart disease
0.958 0.042 0.000
Chapter VIII Diseases of the ear and mastoid process
0.958 0.042 0.000
M54.5 Low back pain
0.956 0.044 0.000
D60-D64 Aplastic and other anaemias
0.956 0.044 0.000
M48 Other spondylopathies
0.951 0.049 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.950 0.050 0.000
M47.8 Other spondylosis
0.949 0.051 0.000
S00 Superficial injury of head
0.948 0.052 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.947 0.053 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.945 0.055 0.000
R00 Abnormalities of heart beat
0.943 0.057 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.942 0.058 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.933 0.067 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.929 0.071 0.000
A30-A49 Other bacterial diseases
0.927 0.073 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.925 0.075 0.000
J43 Emphysema
0.925 0.075 0.000
R25 Abnormal involuntary movements
0.923 0.077 0.000
I69 Sequelae of cerebrovascular disease
0.922 0.078 0.000
D64 Other anaemias
0.922 0.078 0.000
G90-G99 Other disorders of the nervous system
0.919 0.081 0.000
M48.0 Spinal stenosis
0.917 0.083 0.000
G40-G47 Episodic and paroxysmal disorders
0.916 0.084 0.000
B35-B49 Mycoses
0.914 0.086 0.000
H90-H95 Other disorders of ear
0.911 0.089 0.000
F10.2 Dependence syndrome
0.908 0.092 0.000
R00.0 Tachycardia, unspecified
0.907 0.093 0.000
I50 Heart failure
0.905 0.095 0.000
T81 Complications of procedures, not elsewhere classified
0.901 0.099 0.000
F10.1 Harmful use
0.900 0.100 0.000
D64.9 Anaemia, unspecified
0.898 0.102 0.000
Z93 Artificial opening status
0.896 0.104 0.000
Z98 Other postsurgical states
0.894 0.106 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.893 0.107 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.892 0.108 0.000
D69 Purpura and other haemorrhagic conditions
0.892 0.108 0.000
M47.86 Other spondylosis (Lumbar region)
0.891 0.109 0.000
Chapter XXII Codes for special purposes
0.891 0.109 0.000
M70-M79 Other soft tissue disorders
0.890 0.110 0.000
M54.57 Low back pain (Lumbosacral region)
0.889 0.111 0.000
J43.9 Emphysema, unspecified
0.888 0.112 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.883 0.117 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.882 0.118 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.880 0.120 0.000
S02 Fracture of skull and facial bones
0.877 0.123 0.000
R04 Haemorrhage from respiratory passages
0.875 0.125 0.000
I51 Complications and ill-defined descriptions of heart disease
0.875 0.125 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.873 0.127 0.000
M45 Ankylosing spondylitis
0.867 0.133 0.000
J30-J39 Other diseases of upper respiratory tract
0.863 0.137 0.000
I50.0 Congestive heart failure
0.862 0.138 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.861 0.139 0.000
M80-M85 Disorders of bone density and structure
0.861 0.139 0.000
Z34 Supervision of normal pregnancy
0.860 0.140 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.859 0.141 0.000
B37 Candidiasis
0.858 0.142 0.000
G30-G32 Other degenerative diseases of the nervous system
0.855 0.145 0.000
D69.6 Thrombocytopenia, unspecified
0.854 0.146 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.854 0.146 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.853 0.147 0.000
Chapter XIV Diseases of the genitourinary system
0.852 0.148 0.000
M54.9 Dorsalgia, unspecified
0.851 0.149 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.848 0.152 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.848 0.152 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.847 0.153 0.000
G40 Epilepsy
0.847 0.153 0.000
O60-O75 Complications of labour and delivery
0.847 0.153 0.000
A41 Other septicaemia
0.846 0.154 0.000
M48.06 Spinal stenosis (Lumbar region)
0.845 0.155 0.000
R25.1 Tremor, unspecified
0.843 0.157 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.840 0.160 0.000
M54.56 Low back pain (Lumbar region)
0.839 0.161 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.839 0.161 0.000
F10.3 Withdrawal state
0.838 0.162 0.000
S60-S69 Injuries to the wrist and hand
0.838 0.162 0.000
R26 Abnormalities of gait and mobility
0.836 0.164 0.000
I51.7 Cardiomegaly
0.835 0.165 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.834 0.166 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.834 0.166 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.831 0.169 0.000
B95-B98 Bacterial, viral and other infectious agents
0.829 0.171 0.000
H91 Other hearing loss
0.828 0.172 0.000
N17-N19 Renal failure
0.828 0.172 0.000
S40-S49 Injuries to the shoulder and upper arm
0.826 0.174 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.826 0.174 0.000
I50.9 Heart failure, unspecified
0.826 0.174 0.000
S01 Open wound of head
0.826 0.174 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.825 0.175 0.000
S06 Intracranial injury
0.820 0.180 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.818 0.182 0.000
M47.9 Spondylosis, unspecified
0.818 0.182 0.000
S00.9 Superficial injury of head, part unspecified
0.817 0.183 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.816 0.184 0.000
I67 Other cerebrovascular diseases
0.816 0.184 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.816 0.184 0.000
I47 Paroxysmal tachycardia
0.814 0.185 0.000
N10-N16 Renal tubulo-interstitial diseases
0.813 0.187 0.000
G81 Hemiplegia
0.812 0.188 0.000
Z93.3 Colostomy status
0.812 0.188 0.000
F30-F39 Mood [affective] disorders
0.809 0.191 0.000
M47.2 Other spondylosis with radiculopathy
0.808 0.192 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.808 0.192 0.000
Z92 Personal history of medical treatment
0.808 0.192 0.000
Z33 Pregnant state, incidental
0.807 0.193 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.805 0.195 0.000
G93 Other disorders of brain
0.804 0.196 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.803 0.197 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.803 0.197 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.802 0.198 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.802 0.198 0.000
Z90.2 Acquired absence of lung [part of]
0.798 0.202 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.797 0.203 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.796 0.204 0.000
N13 Obstructive and reflux uropathy
0.796 0.204 0.000
Z98.0 Intestinal bypass and anastomosis status
0.795 0.205 0.000
S70-S79 Injuries to the hip and thigh
0.795 0.205 0.000
S00.1 Contusion of eyelid and periocular area
0.794 0.206 0.000
F60-F69 Disorders of adult personality and behaviour
0.792 0.208 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.792 0.208 0.000
S00.8 Superficial injury of other parts of head
0.791 0.209 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.791 0.209 0.000
N17 Acute renal failure
0.791 0.209 0.000
A80-A89 Viral infections of the central nervous system
0.788 0.212 0.000
Chapter II Neoplasms
0.787 0.213 0.000
R94.3 Abnormal results of cardiovascular function studies
0.786 0.214 0.000
S80-S89 Injuries to the knee and lower leg
0.786 0.214 0.000
F10.0 Acute intoxication
0.786 0.214 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.786 0.214 0.000
G70-G73 Diseases of myoneural junction and muscle
0.785 0.215 0.000
D62 Acute posthaemorrhagic anaemia
0.785 0.215 0.000
F80-F89 Disorders of psychological development
0.785 0.215 0.000
M54.1 Radiculopathy
0.784 0.216 0.000
R40 Somnolence, stupor and coma
0.784 0.216 0.000
M54.2 Cervicalgia
0.784 0.216 0.000
Z94 Transplanted organ and tissue status
0.783 0.217 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.783 0.217 0.000
R00.1 Bradycardia, unspecified
0.783 0.217 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.782 0.218 0.000
Z90.1 Acquired absence of breast(s)
0.782 0.218 0.000
J09-J18 Influenza and pneumonia
0.781 0.219 0.000
R50-R69 General symptoms and signs
0.780 0.220 0.000
R45 Symptoms and signs involving emotional state
0.779 0.221 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.779 0.221 0.000
Z89 Acquired absence of limb
0.779 0.221 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.778 0.221 0.000
Chapter XX External causes of morbidity and mortality
0.778 0.222 0.000
M75 Shoulder lesions
0.777 0.223 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.777 0.223 0.000
H65-H75 Diseases of middle ear and mastoid
0.777 0.223 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.776 0.224 0.000
S90-S99 Injuries to the ankle and foot
0.775 0.225 0.000
B37.9 Candidiasis, unspecified
0.775 0.225 0.000
Z22 Carrier of infectious disease
0.774 0.226 0.000
F10.4 Withdrawal state with delirium
0.774 0.226 0.000
S50-S59 Injuries to the elbow and forearm
0.774 0.226 0.000
O80-O84 Delivery
0.774 0.226 0.000
Z30 Contraceptive management
0.774 0.226 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.773 0.227 0.000
A49 Bacterial infection of unspecified site
0.772 0.228 0.000
M54.4 Lumbago with sciatica
0.770 0.230 0.000
H91.9 Hearing loss, unspecified
0.769 0.231 0.000
M50 Cervical disk disorders
0.768 0.232 0.000
S00.0 Superficial injury of scalp
0.767 0.233 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.766 0.234 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.766 0.234 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.764 0.235 0.000
N17.9 Acute renal failure, unspecified
0.764 0.236 0.000
I60 Subarachnoid haemorrhage
0.764 0.236 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.764 0.236 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.763 0.237 0.000
R29.6 Tendency to fall, not elsewhere classified
0.762 0.238 0.000
D50-D53 Nutritional anaemias
0.761 0.239 0.000
M86-M90 Other osteopathies
0.761 0.239 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.760 0.240 0.000
F99-F99 Unspecified mental disorder
0.760 0.240 0.000
I49 Other cardiac arrhythmias
0.760 0.240 0.000
N25-N29 Other disorders of kidney and ureter
0.757 0.243 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.755 0.244 0.000
G81.9 Hemiplegia, unspecified
0.755 0.245 0.000
A41.9 Septicaemia, unspecified
0.755 0.245 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.755 0.245 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.754 0.246 0.000
I31 Other diseases of pericardium
0.753 0.247 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.753 0.247 0.000
H92 Otalgia and effusion of ear
0.753 0.247 0.000
I62 Other nontraumatic intracranial haemorrhage
0.751 0.249 0.000
R04.2 Haemoptysis
0.751 0.249 0.000
O63 Long labour
0.750 0.250 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.750 0.250 0.000
D68 Other coagulation defects
0.747 0.253 0.000
G95 Other diseases of spinal cord
0.747 0.253 0.000
J95-J99 Other diseases of the respiratory system
0.746 0.254 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.745 0.255 0.000
G40.9 Epilepsy, unspecified
0.744 0.256 0.000
R02 Gangrene, not elsewhere classified
0.744 0.256 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.743 0.257 0.000
Z90.5 Acquired absence of kidney
0.743 0.257 0.000
J42 Unspecified chronic bronchitis
0.741 0.259 0.000
I33 Acute and subacute endocarditis
0.741 0.259 0.000
R46 Symptoms and signs involving appearance and behaviour
0.739 0.261 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.739 0.261 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.738 0.262 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.737 0.263 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.737 0.263 0.000
J30 Vasomotor and allergic rhinitis
0.737 0.263 0.000
Z90.3 Acquired absence of part of stomach
0.736 0.264 0.000
L89 Decubitus ulcer
0.735 0.265 0.000
Z39 Postpartum care and examination
0.734 0.266 0.000
R04.0 Epistaxis
0.733 0.267 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.733 0.267 0.000
T86 Failure and rejection of transplanted organs and tissues
0.733 0.267 0.000
M05-M14 Inflammatory polyarthropathies
0.732 0.268 0.000
Z60 Problems related to social environment
0.730 0.270 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.730 0.270 0.000
H90 Conductive and sensorineural hearing loss
0.730 0.270 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.730 0.270 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.729 0.271 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.728 0.272 0.000
M80 Osteoporosis with pathological fracture
0.727 0.273 0.000
Z96 Presence of other functional implants
0.727 0.273 0.000
Z34.8 Supervision of other normal pregnancy
0.727 0.273 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.727 0.273 0.000
G43 Migraine
0.723 0.276 0.000
Z95.0 Presence of cardiac pacemaker
0.723 0.277 0.000
R05 Cough
0.723 0.277 0.000
R52 Pain, not elsewhere classified
0.723 0.277 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.722 0.278 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.721 0.279 0.000
I85 Oesophageal varices
0.721 0.279 0.000
G96 Other disorders of central nervous system
0.721 0.279 0.000
Z98.8 Other specified postsurgical states
0.720 0.280 0.000
M77 Other enthesopathies
0.720 0.280 0.000
Z31 Procreative management
0.720 0.280 0.000
Z93.6 Other artificial openings of urinary tract status
0.719 0.280 0.000
H80-H83 Diseases of inner ear
0.719 0.280 0.000
I46 Cardiac arrest
0.719 0.281 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.718 0.282 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.718 0.282 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M48.02 Spinal stenosis (Cervical region)
0.717 0.283 0.000
G51 Facial nerve disorders
0.716 0.284 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.716 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.284 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.716 0.284 0.000
M49 Spondylopathies in diseases classified elsewhere
0.716 0.284 0.000
B37.8 Candidiasis of other sites
0.716 0.284 0.000
Z84 Family history of other conditions
0.715 0.285 0.000
Z81 Family history of mental and behavioural disorders
0.715 0.285 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.715 0.285 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.714 0.286 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.286 0.000
F70-F79 Mental retardation
0.714 0.286 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.714 0.286 0.000
S20-S29 Injuries to the thorax
0.714 0.286 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.713 0.287 0.000
R25.2 Cramp and spasm
0.713 0.287 0.000
D55-D59 Haemolytic anaemias
0.712 0.287 0.000
B99-B99 Other infectious diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.712 0.288 0.000
B15-B19 Viral hepatitis
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
G35 Multiple sclerosis
0.711 0.288 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.710 0.290 0.000
S08 Traumatic amputation of part of head
0.710 0.290 0.000
S07 Crushing injury of head
0.710 0.290 0.000
S05 Injury of eye and orbit
0.710 0.290 0.000
S04 Injury of cranial nerves
0.710 0.290 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.710 0.290 0.000
S02.1 Fracture of base of skull
0.710 0.290 0.000
M53 Other dorsopathies, not elsewhere classified
0.709 0.291 0.000
M84 Disorders of continuity of bone
0.709 0.291 0.000
S02.4 Fracture of malar and maxillary bones
0.708 0.292 0.000
I00-I02 Acute rheumatic fever
0.708 0.292 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.706 0.293 0.000
I49.9 Cardiac arrhythmia, unspecified
0.706 0.294 0.000
M46 Other inflammatory spondylopathies
0.706 0.294 0.000
B91 Sequelae of poliomyelitis
0.705 0.295 0.000
M47.82 Other spondylosis (Cervical region)
0.704 0.296 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.704 0.296 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.704 0.296 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.704 0.296 0.000
M47.1 Other spondylosis with myelopathy
0.704 0.296 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.704 0.296 0.000
R27 Other lack of coordination
0.703 0.296 0.000
J39 Other diseases of upper respiratory tract
0.703 0.296 0.000
T87 Complications peculiar to reattachment and amputation
0.703 0.297 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.703 0.297 0.000
M54.8 Other dorsalgia
0.703 0.297 0.000
M54.6 Pain in thoracic spine
0.703 0.297 0.000
M54.0 Panniculitis affecting regions of neck and back
0.703 0.297 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.703 0.297 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.703 0.297 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.703 0.297 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.703 0.297 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.703 0.297 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.703 0.297 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.703 0.297 0.000
F11 Mental and behavioural disorders due to use of opioids
0.703 0.297 0.000
I69.3 Sequelae of cerebral infarction
0.703 0.297 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.703 0.297 0.000
R23 Other skin changes
0.703 0.297 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.702 0.297 0.000
R94.7 Abnormal results of other endocrine function studies
0.702 0.297 0.000
R94.6 Abnormal results of thyroid function studies
0.702 0.297 0.000
R94.4 Abnormal results of kidney function studies
0.702 0.297 0.000
R94.2 Abnormal results of pulmonary function studies
0.702 0.297 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.702 0.297 0.000
R94.0 Abnormal results of function studies of central nervous system
0.702 0.297 0.000
M65-M68 Disorders of synovium and tendon
0.701 0.299 0.000
J41 Simple and mucopurulent chronic bronchitis
0.700 0.299 0.000
Z90.0 Acquired absence of part of head and neck
0.700 0.299 0.000
S02.0 Fracture of vault of skull
0.700 0.300 0.000
F10.9 Unspecified mental and behavioural disorder
0.699 0.301 0.000
F10.8 Other mental and behavioural disorders
0.699 0.301 0.000
F10.7 Residual and late-onset psychotic disorder
0.699 0.301 0.000
F10.6 Amnesic syndrome
0.699 0.301 0.000
F10.5 Psychotic disorder
0.699 0.301 0.000
Z35 Supervision of high-risk pregnancy
0.698 0.302 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.698 0.302 0.000
Z22.3 Carrier of other specified bacterial diseases
0.698 0.302 0.000
G93.3 Postviral fatigue syndrome
0.697 0.302 0.000
S40 Superficial injury of shoulder and upper arm
0.697 0.303 0.000
I67.9 Cerebrovascular disease, unspecified
0.697 0.303 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.696 0.304 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.696 0.304 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.695 0.305 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.695 0.305 0.000
U80 Agent resistant to penicillin and related antibiotics
0.695 0.305 0.000
F20 Schizophrenia
0.695 0.305 0.000
R06 Abnormalities of breathing
0.693 0.307 0.000
D80-D89 Certain disorders involving the immune mechanism
0.692 0.308 0.000
M75.1 Rotator cuff syndrome
0.692 0.308 0.000
I80 Phlebitis and thrombophlebitis
0.692 0.308 0.000
J33 Nasal polyp
0.690 0.310 0.000
C79 Secondary malignant neoplasm of other sites
0.688 0.312 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.688 0.312 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.688 0.312 0.000
J36 Peritonsillar abscess
0.687 0.313 0.000
M40-M43 Deforming dorsopathies
0.687 0.313 0.000
I52 Other heart disorders in diseases classified elsewhere
0.687 0.313 0.000
I48 Atrial fibrillation and flutter
0.687 0.313 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.687 0.313 0.000
I41 Myocarditis in diseases classified elsewhere
0.687 0.313 0.000
I40 Acute myocarditis
0.687 0.313 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.687 0.313 0.000
I37 Pulmonary valve disorders
0.687 0.313 0.000
I36 Nonrheumatic tricuspid valve disorders
0.687 0.313 0.000
I32 Pericarditis in diseases classified elsewhere
0.687 0.313 0.000
I30 Acute pericarditis
0.687 0.313 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.687 0.313 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.687 0.313 0.000
M54.55 Low back pain (Thoracolumbar region)
0.686 0.314 0.000
M54.54 Low back pain-Thoracic
0.686 0.314 0.000
M54.53 Low back pain-Cervicothoracic
0.686 0.314 0.000
M54.52 Low back pain-Cervical
0.686 0.314 0.000
M54.51 Low back pain-Occipit-atl-axl
0.686 0.314 0.000
M54.50 Low back pain (Multiple sites in spine)
0.686 0.314 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.685 0.314 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.685 0.315 0.000
R60 Oedema, not elsewhere classified
0.684 0.316 0.000
I05-I09 Chronic rheumatic heart diseases
0.683 0.317 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.683 0.317 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.683 0.317 0.000
Z29 Need for other prophylactic measures
0.682 0.318 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.682 0.318 0.000
M48.9 Spondylopathy, unspecified
0.682 0.318 0.000
M48.8 Other specified spondylopathies
0.682 0.318 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.682 0.318 0.000
M48.4 Fatigue fracture of vertebra
0.682 0.318 0.000
M48.3 Traumatic spondylopathy
0.682 0.318 0.000
M48.2 Kissing spine
0.682 0.318 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.682 0.318 0.000
Z38 Liveborn infants according to place of birth
0.681 0.319 0.000
Z32 Pregnancy examination and test
0.681 0.319 0.000
M47.89 Other spondylosis (Site unspecified)
0.681 0.319 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.681 0.319 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.681 0.319 0.000
M47.84 Other spondylosis (Thoracic region)
0.681 0.319 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.681 0.319 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.681 0.319 0.000
I47.2 Ventricular tachycardia
0.680 0.320 0.000
Z85.6 Personal history of leukaemia
0.680 0.320 0.000
S00.7 Multiple superficial injuries of head
0.680 0.320 0.000
S00.5 Superficial injury of lip and oral cavity
0.680 0.320 0.000
S00.4 Superficial injury of ear
0.680 0.320 0.000
S00.3 Superficial injury of nose
0.680 0.320 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.680 0.320 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.680 0.320 0.000
D75 Other diseases of blood and blood-forming organs
0.680 0.320 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.678 0.322 0.000
Z97 Presence of other devices
0.678 0.322 0.000
I82 Other venous embolism and thrombosis
0.678 0.322 0.000
M54.59 Low back pain (Site unspecified)
0.676 0.324 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.676 0.324 0.000
L89.1 Stage II decubitus ulcer
0.676 0.324 0.000
D67 Hereditary factor IX deficiency
0.675 0.324 0.000
D66 Hereditary factor VIII deficiency
0.675 0.324 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.675 0.324 0.000
L82 Seborrhoeic keratosis
0.675 0.325 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.675 0.325 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.674 0.326 0.000
Z34.0 Supervision of normal first pregnancy
0.674 0.326 0.000
S09 Other and unspecified injuries of head
0.674 0.326 0.000
H66 Suppurative and unspecified otitis media
0.673 0.327 0.000
R01 Cardiac murmurs and other cardiac sounds
0.672 0.328 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.672 0.328 0.000
N19 Unspecified renal failure
0.672 0.328 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.671 0.329 0.000
S01.0 Open wound of scalp
0.669 0.331 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.669 0.331 0.000
A00-A09 Intestinal infectious diseases
0.668 0.332 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.667 0.333 0.000
H93 Other disorders of ear, not elsewhere classified
0.667 0.333 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.667 0.333 0.000
F23 Acute and transient psychotic disorders
0.666 0.334 0.000
T88.5 Other complications of anaesthesia
0.666 0.334 0.000
O85-O92 Complications predominantly related to the puerperium
0.666 0.334 0.000
J45 Asthma
0.665 0.335 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.665 0.335 0.000
R26.3 Immobility
0.665 0.335 0.000
A48 Other bacterial diseases, not elsewhere classified
0.664 0.336 0.000
A44 Bartonellosis
0.664 0.336 0.000
A43 Nocardiosis
0.664 0.336 0.000
A42 Actinomycosis
0.664 0.336 0.000
A40 Streptococcal septicaemia
0.664 0.336 0.000
A39 Meningococcal infection
0.664 0.336 0.000
A37 Whooping cough
0.664 0.336 0.000
A36 Diphtheria
0.664 0.336 0.000
A32 Listeriosis
0.664 0.336 0.000
A31 Infection due to other mycobacteria
0.664 0.336 0.000
A30 Leprosy [Hansen's disease]
0.664 0.336 0.000
A46 Erysipelas
0.664 0.336 0.000
A38 Scarlet fever
0.664 0.336 0.000
A35 Other tetanus
0.664 0.336 0.000
A34 Obstetrical tetanus
0.664 0.336 0.000
A33 Tetanus neonatorum
0.664 0.336 0.000
Z87 Personal history of other diseases and conditions
0.664 0.336 0.000
R43 Disturbances of smell and taste
0.663 0.336 0.000
J43.8 Other emphysema
0.663 0.337 0.000
J43.2 Centrilobular emphysema
0.663 0.337 0.000
J43.1 Panlobular emphysema
0.663 0.337 0.000
J43.0 MacLeod's syndrome
0.663 0.337 0.000
H60-H62 Diseases of external ear
0.663 0.337 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.662 0.338 0.000
I51.8 Other ill-defined heart diseases
0.662 0.338 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.662 0.338 0.000
A49.8 Other bacterial infections of unspecified site
0.662 0.338 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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