TreeWAS – Variant ID: rs80084511

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter II Neoplasms	1.000	0.000	0.000
Chapter XX External causes of morbidity and mortality	0.999	0.001	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.999	0.001	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.998	0.002	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.998	0.002	0.000
M20-M25 Other joint disorders	0.997	0.003	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.996	0.004	0.000
C15-C26 Malignant neoplasms of digestive organs	0.992	0.008	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.986	0.014	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.981	0.019	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.979	0.021	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.977	0.023	0.000
M20 Acquired deformities of fingers and toes	0.975	0.025	0.000
M24 Other specific joint derangements	0.961	0.039	0.000
C18 Malignant neoplasm of colon	0.960	0.040	0.000
Y43 Primarily systemic agents	0.957	0.043	0.000
Chapter VIII Diseases of the ear and mastoid process	0.955	0.045	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.953	0.047	0.000
M86-M90 Other osteopathies	0.949	0.051	0.000
C77.1 Intrathoracic lymph nodes	0.936	0.064	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.933	0.067	0.000
S60-S69 Injuries to the wrist and hand	0.929	0.071	0.000
E10-E14 Diabetes mellitus	0.929	0.071	0.000
O21 Excessive vomiting in pregnancy	0.923	0.077	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.923	0.077	0.000
E11 Non-insulin-dependent diabetes mellitus	0.916	0.084	0.000
C77.2 Intra-abdominal lymph nodes	0.915	0.085	0.000
C80 Malignant neoplasm without specification of site	0.914	0.086	0.000
Y43.3 Other antineoplastic drugs	0.914	0.086	0.000
S40-S49 Injuries to the shoulder and upper arm	0.908	0.092	0.000
M89 Other disorders of bone	0.907	0.093	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.904	0.096	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.903	0.097	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.903	0.097	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.902	0.098	0.000
C25 Malignant neoplasm of pancreas	0.901	0.099	0.000
Y52 Agents primarily affecting the cardiovascular system	0.900	0.100	0.000
T79-T79 Certain early complications of trauma	0.897	0.103	0.000
M20.1 Hallux valgus (acquired)	0.893	0.107	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.891	0.109	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.888	0.112	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.888	0.112	0.000
H90-H95 Other disorders of ear	0.883	0.117	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.881	0.119	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.877	0.123	0.000
C77.0 Lymph nodes of head, face and neck	0.874	0.126	0.000
M20.2 Hallux rigidus	0.872	0.128	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.871	0.129	0.000
H80-H83 Diseases of inner ear	0.870	0.130	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.867	0.133	0.000
O23 Infections of genito-urinary tract in pregnancy	0.865	0.135	0.000
Chapter XXII Codes for special purposes	0.864	0.136	0.000
M25 Other joint disorders, not elsewhere classified	0.861	0.139	0.000
C18.9 Colon, unspecified	0.860	0.140	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.859	0.141	0.000
M80-M85 Disorders of bone density and structure	0.855	0.145	0.000
O16 Unspecified maternal hypertension	0.853	0.147	0.000
E00-E07 Disorders of thyroid gland	0.852	0.148	0.000
M24.0 Loose body in joint	0.845	0.155	0.000
E11.2 With renal complications	0.840	0.160	0.000
M24.1 Other articular cartilage disorders	0.839	0.161	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.836	0.164	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.834	0.166	0.000
S42 Fracture of shoulder and upper arm	0.833	0.167	0.000
S64 Injury of nerves at wrist and hand level	0.832	0.168	0.000
S80-S89 Injuries to the knee and lower leg	0.828	0.172	0.000
C15 Malignant neoplasm of oesophagus	0.824	0.176	0.000
C64-C68 Malignant neoplasms of urinary tract	0.824	0.176	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.823	0.177	0.000
O21.0 Mild hyperemesis gravidarum	0.823	0.177	0.000
M20.0 Deformity of finger(s)	0.822	0.178	0.000
M20.5 Other deformities of toe(s) (acquired)	0.822	0.178	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.822	0.178	0.000
C18.2 Ascending colon	0.820	0.180	0.000
C18.6 Descending colon	0.820	0.180	0.000
M34 Systemic sclerosis	0.819	0.181	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.819	0.181	0.000
O85-O92 Complications predominantly related to the puerperium	0.816	0.184	0.000
M89.9 Disorder of bone, unspecified	0.816	0.184	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.815	0.184	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.813	0.187	0.000
S90-S99 Injuries to the ankle and foot	0.812	0.188	0.000
M22 Disorders of patella	0.810	0.190	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.810	0.190	0.000
M89.0 Algoneurodystrophy	0.810	0.190	0.000
O80-O84 Delivery	0.807	0.193	0.000
Y40 Systemic antibiotics	0.801	0.199	0.000
C44 Other malignant neoplasms of skin	0.798	0.202	0.000
S62 Fracture at wrist and hand level	0.794	0.206	0.000
O60-O75 Complications of labour and delivery	0.793	0.207	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.792	0.208	0.000
C80.9 Malignant neoplasm, unspecified	0.792	0.208	0.000
C18.4 Transverse colon	0.791	0.209	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.790	0.210	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.787	0.213	0.000
S42.2 Fracture of upper end of humerus	0.787	0.213	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.786	0.214	0.000
E11.9 Without complications	0.785	0.215	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.785	0.215	0.000
E20-E35 Disorders of other endocrine glands	0.784	0.216	0.000
M60-M63 Disorders of muscles	0.784	0.216	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.783	0.216	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.783	0.217	0.000
O21.9 Vomiting of pregnancy, unspecified	0.780	0.220	0.000
E11.4 With neurological complications	0.779	0.221	0.000
M91-M94 Chondropathies	0.779	0.221	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.779	0.221	0.000
C23 Malignant neoplasm of gallbladder	0.778	0.222	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.778	0.222	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.777	0.223	0.000
C77.8 Lymph nodes of multiple regions	0.776	0.224	0.000
M25.3 Other instability of joint	0.776	0.224	0.000
H92 Otalgia and effusion of ear	0.775	0.225	0.000
C44.2 Skin of ear and external auricular canal	0.775	0.225	0.000
W20-W49 Exposure to inanimate mechanical forces	0.774	0.226	0.000
M24.7 Protrusio acetabuli	0.774	0.226	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.772	0.228	0.000
M32 Systemic lupus erythematosus	0.771	0.229	0.000
M21 Other acquired deformities of limbs	0.771	0.229	0.000
H80 Otosclerosis	0.771	0.229	0.000
C17 Malignant neoplasm of small intestine	0.768	0.232	0.000
T92 Sequelae of injuries of upper limb	0.767	0.233	0.000
E04 Other non-toxic goitre	0.764	0.236	0.000
Y43.0 Antiallergic and antiemetic drugs	0.763	0.237	0.000
X10-X19 Contact with heat and hot substances	0.763	0.237	0.000
M33 Dermatopolymyositis	0.761	0.239	0.000
M86 Osteomyelitis	0.761	0.239	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.760	0.240	0.000
M35 Other systemic involvement of connective tissue	0.760	0.240	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.760	0.240	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.759	0.241	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.759	0.241	0.000
E06 Thyroiditis	0.759	0.241	0.000
O14.9 Preeclampsia, unspecified	0.758	0.242	0.000
V40-V49 Car occupant injured in transport accident	0.756	0.244	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.755	0.245	0.000
O24 Diabetes mellitus in pregnancy	0.754	0.246	0.000
V80-V89 Other land transport accidents	0.754	0.246	0.000
T21 Burn and corrosion of trunk	0.754	0.246	0.000
S42.20 Fracture of upper end of humerus (closed)	0.754	0.246	0.000
C25.2 Tail of pancreas	0.753	0.247	0.000
O00-O08 Pregnancy with abortive outcome	0.753	0.247	0.000
W50-W64 Exposure to animate mechanical forces	0.752	0.248	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.751	0.249	0.000
C25.9 Pancreas, unspecified	0.750	0.250	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.749	0.251	0.000
C91 Lymphoid leukaemia	0.748	0.252	0.000
Y57 Other and unspecified drugs and medicaments	0.748	0.252	0.000
M24.2 Disorder of ligament	0.744	0.256	0.000
S68 Traumatic amputation of wrist and hand	0.744	0.256	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.743	0.257	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.742	0.258	0.000
Chapter V Mental and behavioural disorders	0.740	0.260	0.000
C77.5 Intrapelvic lymph nodes	0.740	0.260	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.739	0.261	0.000
E11.6 With other specified complications	0.738	0.262	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.737	0.263	0.000
C15.4 Middle third of oesophagus	0.736	0.264	0.000
S32 Fracture of lumbar spine and pelvis	0.735	0.265	0.000
M00-M03 Infectious arthropathies	0.734	0.266	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.733	0.267	0.000
C60-C63 Malignant neoplasms of male genital organs	0.732	0.268	0.000
E11.8 With unspecified complications	0.732	0.268	0.000
H90 Conductive and sensorineural hearing loss	0.731	0.269	0.000
C18.0 Caecum	0.730	0.270	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.729	0.271	0.000
C01 Malignant neoplasm of base of tongue	0.728	0.272	0.000
C77.4 Inguinal and lower limb lymph nodes	0.726	0.274	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.725	0.275	0.000
M30 Polyarteritis nodosa and related conditions	0.725	0.275	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.723	0.277	0.000
E13 Other specified diabetes mellitus	0.722	0.278	0.000
X20-X29 Contact with venomous animals and plants	0.722	0.278	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.721	0.279	0.000
Y77 Ophthalmic devices associated with adverse incidents	0.720	0.280	0.000
C92 Myeloid leukaemia	0.720	0.280	0.000
T66-T78 Other and unspecified effects of external causes	0.719	0.281	0.000
C07 Malignant neoplasm of parotid gland	0.718	0.282	0.000
H91 Other hearing loss	0.718	0.282	0.000
E11.5 With peripheral circulatory complications	0.718	0.282	0.000
Y48 Anaesthetics and therapeutic gases	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283	0.000
Y35-Y36 Legal intervention and operations of war	0.717	0.283	0.000
Y10-Y34 Event of undetermined intent	0.717	0.283	0.000
X85-X99 Assault	0.717	0.283	0.000
X50-X57 Overexertion, travel and privation	0.717	0.283	0.000
X30-X39 Exposure to forces of nature	0.717	0.283	0.000
X00-X09 Exposure to smoke, fire and flames	0.717	0.283	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.717	0.283	0.000
W75-W84 Other accidental threats to breathing	0.717	0.283	0.000
W65-W74 Accidental drowning and submersion	0.717	0.283	0.000
V98-V99 Other and unspecified transport accidents	0.717	0.283	0.000
V95-V97 Air and space transport accidents	0.717	0.283	0.000
V90-V94 Water transport accidents	0.717	0.283	0.000
V70-V79 Bus occupant injured in transport accident	0.717	0.283	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.717	0.283	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.717	0.283	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.717	0.283	0.000
V01-V09 Pedestrian injured in transport accident	0.717	0.283	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.716	0.283	0.000
Y59 Other and unspecified vaccines and biological substances	0.716	0.284	0.000
Y58 Bacterial vaccines	0.716	0.284	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.716	0.284	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.716	0.284	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.716	0.284	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.716	0.284	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.716	0.284	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.716	0.284	0.000
Y00-Y09 Assault	0.716	0.284	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.715	0.285	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.714	0.286	0.000
H83 Other diseases of inner ear	0.713	0.287	0.000
M24.07 Loose body in joint (Ankle and foot)	0.712	0.288	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.711	0.289	0.000
C21 Malignant neoplasm of anus and anal canal	0.711	0.289	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.711	0.289	0.000
Y43.1 Antineoplastic antimetabolites	0.711	0.289	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.711	0.289	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.709	0.291	0.000
Y61 Foreign object accidentally left in body during surgical and medical care	0.709	0.291	0.000
M25.31 Other instability of joint (Shoulder region)	0.709	0.291	0.000
S92 Fracture of foot, except ankle	0.708	0.292	0.000
C81 Hodgkin's disease	0.707	0.293	0.000
T33-T35 Frostbite	0.707	0.293	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.707	0.293	0.000
T00-T07 Injuries involving multiple body regions	0.707	0.293	0.000
S83.2 Tear of meniscus, current	0.707	0.293	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.706	0.294	0.000
M25.7 Osteophyte	0.705	0.295	0.000
V10-V19 Pedal cyclist injured in transport accident	0.705	0.295	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.705	0.295	0.000
M25.9 Joint disorder, unspecified	0.703	0.297	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.702	0.298	0.000
O15 Eclampsia	0.702	0.298	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.702	0.298	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.702	0.298	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.702	0.298	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.701	0.299	0.000
O29 Complications of anaesthesia during pregnancy	0.701	0.299	0.000
O28 Abnormal findings on antenatal screening of mother	0.701	0.299	0.000
O22 Venous complications in pregnancy	0.701	0.299	0.000
O25 Malnutrition in pregnancy	0.701	0.299	0.000
E11.1 With ketoacidosis	0.700	0.299	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.700	0.300	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.700	0.300	0.000
H80.9 Otosclerosis, unspecified	0.700	0.300	0.000
X60-X84 Intentional self-harm	0.698	0.302	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.698	0.302	0.000
Y44 Agents primarily affecting blood constituents	0.697	0.303	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.697	0.303	0.000
M24.02 Loose body in joint (Upper arm)	0.697	0.303	0.000
O80 Single spontaneous delivery	0.696	0.304	0.000
M80 Osteoporosis with pathological fracture	0.696	0.304	0.000
M90 Osteopathies in diseases classified elsewhere	0.696	0.304	0.000
M34.1 CR(E)ST syndrome	0.694	0.306	0.000
M82 Osteoporosis in diseases classified elsewhere	0.693	0.306	0.000
M20.3 Other deformity of hallux (acquired)	0.693	0.307	0.000
E06.3 Autoimmune thyroiditis	0.693	0.307	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.690	0.310	0.000
C18.3 Hepatic flexure	0.690	0.310	0.000
M24.9 Joint derangement, unspecified	0.689	0.311	0.000
M24.6 Ankylosis of joint	0.689	0.311	0.000
M24.5 Contracture of joint	0.689	0.311	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.689	0.311	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.689	0.311	0.000
C18.8 Overlapping lesion of colon	0.688	0.312	0.000
M65-M68 Disorders of synovium and tendon	0.688	0.312	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.687	0.313	0.000
M89.3 Hypertrophy of bone	0.686	0.313	0.000
Y43.9 Primarily systemic agent, unspecified	0.686	0.313	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.686	0.313	0.000
Y43.6 Enzymes, not elsewhere classified	0.686	0.313	0.000
Y43.5 Acidifying and alkalising agents	0.686	0.313	0.000
Y43.2 Antineoplastic natural products	0.686	0.313	0.000
S69 Other and unspecified injuries of wrist and hand	0.686	0.314	0.000
E04.1 Non-toxic single thyroid nodule	0.685	0.315	0.000
T91 Sequelae of injuries of neck and trunk	0.685	0.315	0.000
E14 Unspecified diabetes mellitus	0.684	0.316	0.001
S30 Superficial injury of abdomen, lower back and pelvis	0.684	0.316	0.000
T23 Burn and corrosion of wrist and hand	0.684	0.316	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.683	0.317	0.000
C25.0 Head of pancreas	0.682	0.318	0.000
S67 Crushing injury of wrist and hand	0.681	0.319	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.681	0.319	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.680	0.320	0.000
C25.1 Body of pancreas	0.680	0.320	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.679	0.320	0.000
S31 Open wound of abdomen, lower back and pelvis	0.679	0.321	0.000
Y43.4 Immunosuppressive agents	0.679	0.321	0.000
S62.3 Fracture of other metacarpal bone	0.678	0.322	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.677	0.323	0.000
V20-V29 Motorcycle rider injured in transport accident	0.676	0.324	0.000
C16 Malignant neoplasm of stomach	0.676	0.324	0.000
C49.9 Connective and soft tissue, unspecified	0.675	0.325	0.000
M84 Disorders of continuity of bone	0.675	0.325	0.000
O23.5 Infections of the genital tract in pregnancy	0.675	0.325	0.000
S60 Superficial injury of wrist and hand	0.674	0.325	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.673	0.327	0.000
S10-S19 Injuries to the neck	0.673	0.327	0.000
Y52.1 Calcium-channel blockers	0.673	0.327	0.000
H65-H75 Diseases of middle ear and mastoid	0.673	0.327	0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.672	0.328	0.000
S50-S59 Injuries to the elbow and forearm	0.672	0.328	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.672	0.328	0.000
S99 Other and unspecified injuries of ankle and foot	0.671	0.329	0.000
M25.8 Other specified joint disorders	0.671	0.329	0.000
C44.0 Skin of lip	0.670	0.330	0.000
T93 Sequelae of injuries of lower limb	0.669	0.331	0.000
M22.3 Other derangements of patella	0.669	0.331	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.669	0.331	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.669	0.331	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.669	0.331	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.669	0.331	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.669	0.331	0.000
M35.0 Sicca syndrome [Sjogren]	0.668	0.332	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.668	0.332	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.668	0.332	0.000
S70-S79 Injuries to the hip and thigh	0.667	0.333	0.000
S65 Injury of blood vessels at wrist and hand level	0.666	0.334	0.000
E12 Malnutrition-related diabetes mellitus	0.666	0.334	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.666	0.334	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.666	0.334	0.000
E11.0 With coma	0.664	0.336	0.000
O26.8 Other specified pregnancy-related conditions	0.664	0.336	0.000
O21.8 Other vomiting complicating pregnancy	0.662	0.338	0.000
O21.2 Late vomiting of pregnancy	0.662	0.338	0.000
M22.4 Chondromalacia patellae	0.662	0.338	0.000
M40-M43 Deforming dorsopathies	0.661	0.339	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.661	0.339	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.661	0.339	0.000
C45 Mesothelioma	0.661	0.339	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.660	0.340	0.000
C18.5 Splenic flexure	0.660	0.340	0.000
O26.9 Pregnancy-related condition, unspecified	0.659	0.341	0.000
O73 Retained placenta and membranes, without haemorrhage	0.659	0.341	0.000
C78.0 Secondary malignant neoplasm of lung	0.658	0.342	0.000
E11.7 With multiple complications	0.656	0.343	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.655	0.345	0.000
O14.0 Moderate preeclampsia	0.655	0.345	0.000
M89.98 Disorder of bone, unspecified (Other)	0.654	0.346	0.000
O90 Complications of the puerperium, not elsewhere classified	0.654	0.346	0.000
M89.03 Algoneurodystrophy (Forearm)	0.653	0.347	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.652	0.348	0.000
S48 Traumatic amputation of shoulder and upper arm	0.651	0.349	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.651	0.349	0.000
S44 Injury of nerves at shoulder and upper arm level	0.651	0.349	0.000
S47 Crushing injury of shoulder and upper arm	0.651	0.349	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.651	0.349	0.000
M25.77 Osteophyte (Ankle and foot)	0.651	0.349	0.000
E27 Other disorders of adrenal gland	0.651	0.349	0.000
M89.8 Other specified disorders of bone	0.650	0.349	0.000
M89.6 Osteopathy after poliomyelitis	0.650	0.349	0.000
M89.5 Osteolysis	0.650	0.349	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.650	0.349	0.000
M89.2 Other disorders of bone development and growth	0.650	0.349	0.000
M89.1 Epiphyseal arrest	0.650	0.349	0.000
M87 Osteonecrosis	0.650	0.350	0.000
M85 Other disorders of bone density and structure	0.649	0.351	0.000
Y45.0 Opioids and related analgesics	0.648	0.352	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.648	0.352	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.648	0.352	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.648	0.352	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.648	0.352	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.648	0.352	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.648	0.352	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.648	0.352	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.648	0.352	0.000
Y51.0 Anticholinesterase agents	0.648	0.352	0.000
O80.0 Spontaneous vertex delivery	0.648	0.352	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.648	0.352	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.648	0.352	0.000
S37 Injury of urinary and pelvic organs	0.648	0.352	0.000
S36 Injury of intra-abdominal organs	0.648	0.352	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.648	0.352	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.648	0.352	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.648	0.352	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.647	0.353	0.000
C95 Leukaemia of unspecified cell type	0.647	0.353	0.000
C94 Other leukaemias of specified cell type	0.647	0.353	0.000
C93 Monocytic leukaemia	0.647	0.353	0.000
C88 Malignant immunoproliferative diseases	0.647	0.353	0.000
C86 Other specified types of T/NK-cell lymphoma	0.647	0.353	0.000
H92.0 Otalgia	0.646	0.354	0.000
C25.8 Overlapping lesion of pancreas	0.646	0.354	0.000
C25.7 Other parts of pancreas	0.646	0.354	0.000
C25.4 Endocrine pancreas	0.646	0.354	0.000
C25.3 Pancreatic duct	0.646	0.354	0.000
F03 Unspecified dementia	0.646	0.354	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.645	0.355	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.645	0.355	0.000
Y52.7 Peripheral vasodilators	0.645	0.355	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.645	0.355	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.645	0.355	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.644	0.355	0.000
W00-W19 Falls	0.644	0.355	0.000
H92.1 Otorrhoea	0.643	0.357	0.000
S40 Superficial injury of shoulder and upper arm	0.643	0.357	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.643	0.357	0.000
E28 Ovarian dysfunction	0.643	0.357	0.000
E03 Other hypothyroidism	0.642	0.358	0.000
M88 Paget's disease of bone [osteitis deformans]	0.641	0.358	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.640	0.360	0.000
S41 Open wound of shoulder and upper arm	0.640	0.360	0.000
C78.2 Secondary malignant neoplasm of pleura	0.639	0.361	0.000
M45-M49 Spondylopathies	0.639	0.361	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.639	0.361	0.000
C46 Kaposi's sarcoma	0.639	0.361	0.000
S64.4 Injury of digital nerve of other finger	0.638	0.362	0.000
D00-D09 In situ neoplasms	0.638	0.362	0.000
C09 Malignant neoplasm of tonsil	0.637	0.363	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.637	0.363	0.000
T25 Burn and corrosion of ankle and foot	0.637	0.363	0.000
T20 Burn and corrosion of head and neck	0.637	0.363	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.637	0.363	0.000
C13 Malignant neoplasm of hypopharynx	0.637	0.363	0.000
C11 Malignant neoplasm of nasopharynx	0.637	0.363	0.000
C10 Malignant neoplasm of oropharynx	0.637	0.363	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.637	0.363	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.637	0.363	0.000
C05 Malignant neoplasm of palate	0.637	0.363	0.000
C04 Malignant neoplasm of floor of mouth	0.637	0.363	0.000
C03 Malignant neoplasm of gum	0.637	0.363	0.000
C00 Malignant neoplasm of lip	0.637	0.363	0.000
C12 Malignant neoplasm of pyriform sinus	0.637	0.363	0.000
O85 Puerperal sepsis	0.636	0.364	0.000
Y65 Other misadventures during surgical and medical care	0.636	0.364	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.636	0.364	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.636	0.364	0.000
Y40.9 Systemic antibiotic, unspecified	0.635	0.365	0.000
Y60.4 During endoscopic examination	0.634	0.366	0.000
S42.1 Fracture of scapula	0.634	0.366	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.633	0.366	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.633	0.367	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.633	0.367	0.000
E04.2 Non-toxic multinodular goitre	0.633	0.367	0.000
S62.2 Fracture of first metacarpal bone	0.633	0.367	0.000
O62 Abnormalities of forces of labour	0.632	0.368	0.000
U80 Agent resistant to penicillin and related antibiotics	0.632	0.368	0.000
W29 Contact with other powered hand tools and household machinery	0.631	0.369	0.000
C18.7 Sigmoid colon	0.631	0.369	0.000
H81 Disorders of vestibular function	0.631	0.369	0.000
M62 Other disorders of muscle	0.630	0.370	0.000
S42.3 Fracture of shaft of humerus	0.630	0.370	0.000
T95 Sequelae of burns, corrosions and frostbite	0.629	0.371	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.629	0.371	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.629	0.371	0.000
S80 Superficial injury of lower leg	0.629	0.371	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.627	0.373	0.000
C43 Malignant melanoma of skin	0.626	0.374	0.000
Y64 Contaminated medical or biological substances	0.624	0.376	0.000
Y63 Failure in dosage during surgical and medical care	0.624	0.376	0.000
Y62 Failure of sterile precautions during surgical and medical care	0.624	0.376	0.000
Y69 Unspecified misadventure during surgical and medical care	0.624	0.376	0.000
Y66 Nonadministration of surgical and medical care	0.624	0.376	0.000
C15.5 Lower third of oesophagus	0.624	0.376	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.623	0.376	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.623	0.377	0.000
T21.0 Burn of unspecified degree of trunk	0.622	0.378	0.000
Y40.3 Macrolides	0.622	0.378	0.000
Y82 Other and unspecified medical devices associated with adverse incidents	0.622	0.378	0.000
Y81 General- and plastic-surgery devices associated with adverse incidents	0.622	0.378	0.000
Y80 Physical medicine devices associated with adverse incidents	0.622	0.378	0.000
Y78 Radiological devices associated with adverse incidents	0.622	0.378	0.000
Y75 Neurological devices associated with adverse incidents	0.622	0.378	0.000
Y74 General hospital and personal-use devices associated with adverse incidents	0.622	0.378	0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.622	0.378	0.000
Y72 Otorhinolaryngological devices associated with adverse incidents	0.622	0.378	0.000
Y71 Cardiovascular devices associated with adverse incidents	0.622	0.378	0.000
Y70 Anaesthesiology devices associated with adverse incidents	0.622	0.378	0.000
C18.1 Appendix	0.622	0.378	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.621	0.379	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.620	0.380	0.000
O23.2 Infections of urethra in pregnancy	0.620	0.380	0.000
O23.1 Infections of bladder in pregnancy	0.620	0.380	0.000
O23.0 Infections of kidney in pregnancy	0.620	0.380	0.000
M89.04 Algoneurodystrophy (Hand)	0.619	0.381	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.618	0.382	0.000
M25.2 Flail joint	0.618	0.382	0.000
M25.1 Fistula of joint	0.618	0.382	0.000
O02 Other abnormal products of conception	0.618	0.382	0.000
O14.2 HELLP syndrome	0.616	0.384	0.000
O14.1 Severe preeclampsia	0.616	0.384	0.000
S64.1 Injury of median nerve at wrist and hand level	0.616	0.384	0.000
S62.7 Multiple fractures of fingers	0.616	0.384	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.615	0.385	0.000
Y45.1 Salicylates	0.615	0.385	0.000
Y77.3 Surgical instruments, materials and devices (including sutures)	0.615	0.385	0.000
H93 Other disorders of ear, not elsewhere classified	0.613	0.387	0.000
M83 Adult osteomalacia	0.613	0.387	0.000
M94 Other disorders of cartilage	0.613	0.387	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.613	0.387	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.613	0.387	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.612	0.388	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.612	0.388	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.611	0.388	0.000
S62.5 Fracture of thumb	0.611	0.389	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.611	0.389	0.000
E00 Congenital iodine-deficiency syndrome	0.611	0.389	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations