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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80098689
log Bayes Factor = 14.847
Chromosome 2   position 167,262,238  (GRCh37) Explore rs80098689 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
L00-L08 Infections of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
L03 Cellulitis
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
L03.3 Cellulitis of trunk
0.994 0.006 0.000
M20-M25 Other joint disorders
0.993 0.007 0.000
K82 Other diseases of gallbladder
0.987 0.013 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.986 0.014 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.985 0.015 0.000
K70-K77 Diseases of liver
0.982 0.018 0.000
F30-F39 Mood [affective] disorders
0.975 0.025 0.000
Chapter XX External causes of morbidity and mortality
0.975 0.025 0.000
K82.8 Other specified diseases of gallbladder
0.974 0.026 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.973 0.027 0.000
A30-A49 Other bacterial diseases
0.969 0.031 0.000
A00-A09 Intestinal infectious diseases
0.968 0.032 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.967 0.033 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.964 0.036 0.000
L08 Other local infections of skin and subcutaneous tissue
0.955 0.045 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.954 0.046 0.000
M80-M85 Disorders of bone density and structure
0.953 0.047 0.000
M23 Internal derangement of knee
0.951 0.049 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.947 0.053 0.000
F10.2 Dependence syndrome
0.946 0.054 0.000
K74 Fibrosis and cirrhosis of liver
0.939 0.061 0.000
L03.1 Cellulitis of other parts of limb
0.932 0.068 0.000
Chapter X Diseases of the respiratory system
0.931 0.069 0.000
Chapter IX Diseases of the circulatory system
0.929 0.071 0.000
J09-J18 Influenza and pneumonia
0.926 0.074 0.000
D60-D64 Aplastic and other anaemias
0.926 0.074 0.000
J18 Pneumonia, organism unspecified
0.923 0.077 0.000
D70 Agranulocytosis
0.922 0.078 0.000
Chapter VII Diseases of the eye and adnexa
0.920 0.080 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.919 0.081 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.912 0.088 0.000
J18.1 Lobar pneumonia, unspecified
0.911 0.089 0.000
M34 Systemic sclerosis
0.911 0.089 0.000
F31 Bipolar affective disorder
0.910 0.090 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.909 0.091 0.000
K83 Other diseases of biliary tract
0.906 0.094 0.000
I80 Phlebitis and thrombophlebitis
0.906 0.094 0.000
Chapter XIV Diseases of the genitourinary system
0.903 0.097 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.903 0.097 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.903 0.097 0.000
Chapter XXII Codes for special purposes
0.902 0.098 0.000
A49 Bacterial infection of unspecified site
0.900 0.100 0.000
M25 Other joint disorders, not elsewhere classified
0.899 0.101 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.898 0.102 0.000
A08 Viral and other specified intestinal infections
0.891 0.109 0.000
N60-N64 Disorders of breast
0.889 0.111 0.000
H53-H54 Visual disturbances and blindness
0.886 0.114 0.000
A04 Other bacterial intestinal infections
0.882 0.118 0.000
J18.9 Pneumonia, unspecified
0.882 0.118 0.000
K86 Other diseases of pancreas
0.881 0.119 0.000
M50-M54 Other dorsopathies
0.879 0.121 0.000
Y52 Agents primarily affecting the cardiovascular system
0.875 0.125 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.873 0.127 0.000
H53 Visual disturbances
0.870 0.130 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.866 0.134 0.000
D64 Other anaemias
0.864 0.136 0.000
K74.6 Other and unspecified cirrhosis of liver
0.863 0.137 0.000
Y95 Nosocomial condition
0.861 0.139 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.861 0.139 0.000
M23.3 Other meniscus derangements
0.861 0.139 0.000
A41 Other septicaemia
0.860 0.140 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.857 0.143 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.857 0.143 0.000
N63 Unspecified lump in breast
0.857 0.143 0.000
M81 Osteoporosis without pathological fracture
0.855 0.145 0.000
M21 Other acquired deformities of limbs
0.852 0.148 0.000
N40-N51 Diseases of male genital organs
0.850 0.150 0.000
F60-F69 Disorders of adult personality and behaviour
0.849 0.151 0.000
K22 Other diseases of oesophagus
0.845 0.155 0.000
F33 Recurrent depressive disorder
0.845 0.155 0.000
M54 Dorsalgia
0.844 0.156 0.000
K22.2 Oesophageal obstruction
0.843 0.157 0.000
L89 Decubitus ulcer
0.842 0.158 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.838 0.162 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.834 0.166 0.000
F32 Depressive episode
0.828 0.172 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.827 0.173 0.000
H53.2 Diplopia
0.826 0.174 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.825 0.175 0.000
A08.4 Viral intestinal infection, unspecified
0.823 0.177 0.000
Chapter VI Diseases of the nervous system
0.822 0.178 0.000
D69 Purpura and other haemorrhagic conditions
0.821 0.179 0.000
D64.9 Anaemia, unspecified
0.821 0.179 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.820 0.180 0.000
K74.3 Primary biliary cirrhosis
0.820 0.180 0.000
B35-B49 Mycoses
0.819 0.181 0.000
A49.8 Other bacterial infections of unspecified site
0.808 0.192 0.000
L03.9 Cellulitis, unspecified
0.807 0.193 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.807 0.193 0.000
K80 Cholelithiasis
0.806 0.194 0.000
K82.4 Cholesterolosis of gallbladder
0.805 0.195 0.000
M34.9 Systemic sclerosis, unspecified
0.803 0.196 0.000
M25.5 Pain in joint
0.802 0.198 0.000
H53.0 Amblyopia ex anopsia
0.802 0.198 0.000
K75 Other inflammatory liver diseases
0.800 0.200 0.000
L91 Hypertrophic disorders of skin
0.799 0.201 0.000
N50 Other disorders of male genital organs
0.796 0.204 0.000
M80 Osteoporosis with pathological fracture
0.796 0.204 0.000
N48 Other disorders of penis
0.796 0.204 0.000
M31 Other necrotising vasculopathies
0.794 0.206 0.000
M91-M94 Chondropathies
0.793 0.206 0.000
K83.1 Obstruction of bile duct
0.793 0.207 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.787 0.213 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.786 0.214 0.000
K82.9 Disease of gallbladder, unspecified
0.786 0.214 0.000
A46 Erysipelas
0.782 0.218 0.000
F17.2 Dependence syndrome
0.781 0.219 0.000
Y40 Systemic antibiotics
0.781 0.219 0.000
M54.5 Low back pain
0.781 0.219 0.000
K65-K67 Diseases of peritoneum
0.781 0.219 0.000
T91 Sequelae of injuries of neck and trunk
0.781 0.219 0.000
S20-S29 Injuries to the thorax
0.780 0.219 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.779 0.221 0.000
M81.9 Osteoporosis, unspecified
0.779 0.221 0.000
K29 Gastritis and duodenitis
0.779 0.221 0.000
F10.3 Withdrawal state
0.779 0.221 0.000
A02 Other Salmonella infections
0.778 0.222 0.000
D69.6 Thrombocytopenia, unspecified
0.777 0.223 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.776 0.224 0.000
K76 Other diseases of liver
0.776 0.224 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.775 0.225 0.000
L84 Corns and callosities
0.775 0.225 0.000
L50-L54 Urticaria and erythema
0.775 0.225 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.774 0.226 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.771 0.228 0.000
K73 Chronic hepatitis, not elsewhere classified
0.771 0.229 0.000
A04.8 Other specified bacterial intestinal infections
0.771 0.229 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.771 0.229 0.000
M34.1 CR(E)ST syndrome
0.770 0.229 0.000
M86-M90 Other osteopathies
0.769 0.231 0.000
X60-X84 Intentional self-harm
0.769 0.231 0.000
N64 Other disorders of breast
0.768 0.232 0.000
M23.5 Chronic instability of knee
0.767 0.233 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.766 0.234 0.000
V80-V89 Other land transport accidents
0.766 0.234 0.000
K70 Alcoholic liver disease
0.765 0.235 0.000
A41.9 Septicaemia, unspecified
0.765 0.235 0.000
D72 Other disorders of white blood cells
0.764 0.236 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.764 0.236 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.764 0.236 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.764 0.236 0.000
K29.5 Chronic gastritis, unspecified
0.763 0.237 0.000
H10-H13 Disorders of conjunctiva
0.763 0.237 0.000
M70-M79 Other soft tissue disorders
0.761 0.239 0.000
T92 Sequelae of injuries of upper limb
0.760 0.240 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.760 0.240 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.760 0.240 0.000
F99-F99 Unspecified mental disorder
0.757 0.242 0.000
I89.0 Lymphoedema, not elsewhere classified
0.755 0.245 0.000
D55-D59 Haemolytic anaemias
0.755 0.245 0.000
D61 Other aplastic anaemias
0.754 0.246 0.000
M85 Other disorders of bone density and structure
0.754 0.246 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.753 0.247 0.000
M65-M68 Disorders of synovium and tendon
0.753 0.247 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.752 0.248 0.000
M35 Other systemic involvement of connective tissue
0.751 0.249 0.000
J81 Pulmonary oedema
0.751 0.249 0.000
K83.8 Other specified diseases of biliary tract
0.750 0.250 0.000
J00-J06 Acute upper respiratory infections
0.749 0.251 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.747 0.253 0.000
K72 Hepatic failure, not elsewhere classified
0.747 0.253 0.000
T90 Sequelae of injuries of head
0.746 0.254 0.000
D73 Diseases of spleen
0.745 0.255 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.745 0.255 0.000
F32.9 Depressive episode, unspecified
0.744 0.256 0.000
Y57 Other and unspecified drugs and medicaments
0.744 0.256 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.744 0.256 0.000
J14 Pneumonia due to Haemophilus influenzae
0.744 0.256 0.000
F31.9 Bipolar affective disorder, unspecified
0.742 0.258 0.000
F60 Specific personality disorders
0.742 0.258 0.000
M84 Disorders of continuity of bone
0.741 0.259 0.000
L83 Acanthosis nigricans
0.741 0.259 0.000
I05-I09 Chronic rheumatic heart diseases
0.740 0.260 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.740 0.260 0.000
Chapter VIII Diseases of the ear and mastoid process
0.740 0.260 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.740 0.260 0.000
N50.1 Vascular disorders of male genital organs
0.739 0.261 0.000
M54.59 Low back pain (Site unspecified)
0.739 0.261 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.739 0.261 0.000
K85 Acute pancreatitis
0.737 0.263 0.000
W50-W64 Exposure to animate mechanical forces
0.737 0.263 0.000
L03.2 Cellulitis of face
0.737 0.263 0.000
G90-G99 Other disorders of the nervous system
0.736 0.264 0.000
I60-I69 Cerebrovascular diseases
0.734 0.265 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.733 0.267 0.000
M25.8 Other specified joint disorders
0.732 0.267 0.000
I86 Varicose veins of other sites
0.732 0.268 0.000
S80-S89 Injuries to the knee and lower leg
0.731 0.269 0.000
M24 Other specific joint derangements
0.731 0.269 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.730 0.270 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.730 0.270 0.000
Y45.0 Opioids and related analgesics
0.729 0.271 0.000
S90-S99 Injuries to the ankle and foot
0.725 0.275 0.000
I81 Portal vein thrombosis
0.725 0.275 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.725 0.275 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.725 0.275 0.000
L03.8 Cellulitis of other sites
0.723 0.277 0.000
Y52.1 Calcium-channel blockers
0.722 0.278 0.000
B15-B19 Viral hepatitis
0.721 0.279 0.000
U80 Agent resistant to penicillin and related antibiotics
0.719 0.281 0.000
N00-N08 Glomerular diseases
0.719 0.281 0.000
A49.9 Bacterial infection, unspecified
0.719 0.281 0.000
K86.8 Other specified diseases of pancreas
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
L10-L14 Bullous disorders
0.717 0.283 0.000
N42 Other disorders of prostate
0.717 0.283 0.000
L04 Acute lymphadenitis
0.717 0.283 0.000
L01 Impetigo
0.717 0.283 0.000
L00 Staphylococcal scalded skin syndrome
0.717 0.283 0.000
K26 Duodenal ulcer
0.717 0.283 0.000
H53.9 Visual disturbance, unspecified
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
M25.4 Effusion of joint
0.715 0.284 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.715 0.285 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.714 0.286 0.000
B99-B99 Other infectious diseases
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B65-B83 Helminthiases
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
V10-V19 Pedal cyclist injured in transport accident
0.713 0.287 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.712 0.288 0.000
M33 Dermatopolymyositis
0.712 0.288 0.000
M32 Systemic lupus erythematosus
0.712 0.288 0.000
M30 Polyarteritis nodosa and related conditions
0.712 0.288 0.000
L05 Pilonidal cyst
0.710 0.290 0.000
N62 Hypertrophy of breast
0.709 0.291 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.708 0.292 0.000
K82.3 Fistula of gallbladder
0.708 0.292 0.000
K82.2 Perforation of gallbladder
0.708 0.292 0.000
K82.1 Hydrops of gallbladder
0.708 0.292 0.000
K82.0 Obstruction of gallbladder
0.708 0.292 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.707 0.293 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.707 0.293 0.000
L94 Other localised connective tissue disorders
0.707 0.293 0.000
L93 Lupus erythematosus
0.707 0.293 0.000
L87 Transepidermal elimination disorders
0.707 0.293 0.000
L88 Pyoderma gangrenosum
0.707 0.293 0.000
L86 Keratoderma in diseases classified elsewhere
0.707 0.293 0.000
L80 Vitiligo
0.707 0.293 0.000
N48.2 Other inflammatory disorders of penis
0.707 0.293 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.706 0.294 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.706 0.294 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.706 0.294 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.706 0.294 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.706 0.294 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.706 0.294 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.706 0.294 0.000
F11 Mental and behavioural disorders due to use of opioids
0.706 0.294 0.000
A49.0 Staphylococcal infection, unspecified
0.706 0.294 0.000
M21.2 Flexion deformity
0.706 0.294 0.000
D50-D53 Nutritional anaemias
0.706 0.294 0.000
K86.9 Disease of pancreas, unspecified
0.706 0.294 0.000
L81 Other disorders of pigmentation
0.704 0.295 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.704 0.296 0.000
K77 Liver disorders in diseases classified elsewhere
0.704 0.296 0.000
K71 Toxic liver disease
0.704 0.296 0.000
D80-D89 Certain disorders involving the immune mechanism
0.704 0.296 0.000
M54.3 Sciatica
0.704 0.296 0.000
L03.0 Cellulitis of finger and toe
0.704 0.296 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.703 0.297 0.000
F38 Other mood [affective] disorders
0.699 0.301 0.000
F34 Persistent mood [affective] disorders
0.699 0.301 0.000
F30 Manic episode
0.699 0.301 0.000
F39 Unspecified mood [affective] disorder
0.699 0.301 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.699 0.301 0.000
Y35-Y36 Legal intervention and operations of war
0.699 0.301 0.000
Y10-Y34 Event of undetermined intent
0.699 0.301 0.000
Y00-Y09 Assault
0.699 0.301 0.000
X85-X99 Assault
0.699 0.301 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.699 0.301 0.000
X50-X57 Overexertion, travel and privation
0.699 0.301 0.000
X30-X39 Exposure to forces of nature
0.699 0.301 0.000
X20-X29 Contact with venomous animals and plants
0.699 0.301 0.000
X10-X19 Contact with heat and hot substances
0.699 0.301 0.000
X00-X09 Exposure to smoke, fire and flames
0.699 0.301 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.699 0.301 0.000
W75-W84 Other accidental threats to breathing
0.699 0.301 0.000
W65-W74 Accidental drowning and submersion
0.699 0.301 0.000
V98-V99 Other and unspecified transport accidents
0.699 0.301 0.000
V95-V97 Air and space transport accidents
0.699 0.301 0.000
V90-V94 Water transport accidents
0.699 0.301 0.000
V70-V79 Bus occupant injured in transport accident
0.699 0.301 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.699 0.301 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.699 0.301 0.000
V40-V49 Car occupant injured in transport accident
0.699 0.301 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.699 0.301 0.000
V01-V09 Pedestrian injured in transport accident
0.699 0.301 0.000
K76.6 Portal hypertension
0.697 0.303 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.697 0.303 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.697 0.303 0.000
K74.0 Hepatic fibrosis
0.696 0.303 0.000
A04.5 Campylobacter enteritis
0.695 0.305 0.000
A48 Other bacterial diseases, not elsewhere classified
0.695 0.305 0.000
A44 Bartonellosis
0.695 0.305 0.000
A43 Nocardiosis
0.695 0.305 0.000
A42 Actinomycosis
0.695 0.305 0.000
A40 Streptococcal septicaemia
0.695 0.305 0.000
A39 Meningococcal infection
0.695 0.305 0.000
A37 Whooping cough
0.695 0.305 0.000
A36 Diphtheria
0.695 0.305 0.000
A32 Listeriosis
0.695 0.305 0.000
A31 Infection due to other mycobacteria
0.695 0.305 0.000
A30 Leprosy [Hansen's disease]
0.695 0.305 0.000
A38 Scarlet fever
0.695 0.305 0.000
A35 Other tetanus
0.695 0.305 0.000
A34 Obstetrical tetanus
0.695 0.305 0.000
A33 Tetanus neonatorum
0.695 0.305 0.000
W20-W49 Exposure to inanimate mechanical forces
0.695 0.305 0.000
A07 Other protozoal intestinal diseases
0.694 0.306 0.000
A06 Amoebiasis
0.694 0.306 0.000
A05 Other bacterial foodborne intoxications
0.694 0.306 0.000
A03 Shigellosis
0.694 0.306 0.000
A01 Typhoid and paratyphoid fevers
0.694 0.306 0.000
A00 Cholera
0.694 0.306 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.693 0.306 0.000
D74 Methaemoglobinaemia
0.693 0.307 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.693 0.307 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.693 0.307 0.000
L60-L75 Disorders of skin appendages
0.693 0.307 0.000
D68 Other coagulation defects
0.692 0.307 0.000
H60-H62 Diseases of external ear
0.692 0.308 0.000
M22 Disorders of patella
0.692 0.308 0.000
F10.9 Unspecified mental and behavioural disorder
0.691 0.309 0.000
F10.8 Other mental and behavioural disorders
0.691 0.309 0.000
F10.7 Residual and late-onset psychotic disorder
0.691 0.309 0.000
F10.6 Amnesic syndrome
0.691 0.309 0.000
F10.5 Psychotic disorder
0.691 0.309 0.000
F10.4 Withdrawal state with delirium
0.691 0.309 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.690 0.310 0.000
T66-T78 Other and unspecified effects of external causes
0.689 0.311 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.689 0.311 0.000
B25-B34 Other viral diseases
0.689 0.311 0.000
L82 Seborrhoeic keratosis
0.687 0.313 0.000
Q60-Q64 Congenital malformations of the urinary system
0.686 0.314 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.686 0.314 0.000
L89.2 Stage III decubitus ulcer
0.686 0.314 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.685 0.314 0.000
L08.1 Erythrasma
0.685 0.315 0.000
L08.0 Pyoderma
0.685 0.315 0.000
K86.1 Other chronic pancreatitis
0.684 0.316 0.000
T79-T79 Certain early complications of trauma
0.684 0.316 0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.684 0.316 0.000
N61 Inflammatory disorders of breast
0.684 0.316 0.000
I85 Oesophageal varices
0.684 0.316 0.000
T33-T35 Frostbite
0.684 0.316 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.684 0.316 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.684 0.316 0.000
T00-T07 Injuries involving multiple body regions
0.684 0.316 0.000
S10-S19 Injuries to the neck
0.684 0.316 0.000
M83 Adult osteomalacia
0.683 0.317 0.000
M82 Osteoporosis in diseases classified elsewhere
0.683 0.317 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.683 0.317 0.000
M45-M49 Spondylopathies
0.683 0.317 0.000
I83 Varicose veins of lower extremities
0.683 0.317 0.000
I87 Other disorders of veins
0.682 0.318 0.000
M23.9 Internal derangement of knee, unspecified
0.682 0.318 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.682 0.318 0.000
M23.1 Discoid meniscus (congenital)
0.682 0.318 0.000
M23.0 Cystic meniscus
0.682 0.318 0.000
M54.9 Dorsalgia, unspecified
0.681 0.319 0.000
L89.1 Stage II decubitus ulcer
0.680 0.320 0.000
G62 Other polyneuropathies
0.679 0.321 0.000
Y59 Other and unspecified vaccines and biological substances
0.679 0.321 0.000
Y58 Bacterial vaccines
0.679 0.321 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.679 0.321 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.679 0.321 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.679 0.321 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.679 0.321 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.679 0.321 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.679 0.321 0.000
Y48 Anaesthetics and therapeutic gases
0.679 0.321 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.679 0.321 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.679 0.321 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.679 0.321 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.678 0.322 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.678 0.322 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.677 0.323 0.000
D75 Other diseases of blood and blood-forming organs
0.676 0.324 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.675 0.324 0.000
H55-H59 Other disorders of eye and adnexa
0.675 0.325 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.675 0.325 0.000
G70-G73 Diseases of myoneural junction and muscle
0.674 0.326 0.000
K74.5 Biliary cirrhosis, unspecified
0.673 0.327 0.000
K74.4 Secondary biliary cirrhosis
0.673 0.327 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.673 0.327 0.000
K74.1 Hepatic sclerosis
0.673 0.327 0.000
N10-N16 Renal tubulo-interstitial diseases
0.673 0.327 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.672 0.328 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.669 0.331 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.667 0.333 0.000
I00-I02 Acute rheumatic fever
0.666 0.334 0.000
M25.56 Pain in joint (Lower leg)
0.665 0.335 0.000
K83.0 Cholangitis
0.665 0.335 0.000
J95-J99 Other diseases of the respiratory system
0.665 0.335 0.000
F10.0 Acute intoxication
0.665 0.335 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.665 0.335 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.664 0.336 0.000
J17 Pneumonia in diseases classified elsewhere
0.664 0.336 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.664 0.336 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.664 0.336 0.000
J12 Viral pneumonia, not elsewhere classified
0.664 0.336 0.000
J11 Influenza, virus not identified
0.664 0.336 0.000
J10 Influenza due to identified influenza virus
0.664 0.336 0.000
J09 Influenza due to certain identified influenza virus
0.664 0.336 0.000
M21.0 Valgus deformity, not elsewhere classified
0.664 0.336 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.664 0.336 0.000
K22.9 Disease of oesophagus, unspecified
0.663 0.337 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.662 0.338 0.000
J18.8 Other pneumonia, organism unspecified
0.661 0.338 0.000
J18.2 Hypostatic pneumonia, unspecified
0.661 0.338 0.000
V20-V29 Motorcycle rider injured in transport accident
0.661 0.339 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.660 0.340 0.000
B49 Unspecified mycosis
0.660 0.340 0.000
M05-M14 Inflammatory polyarthropathies
0.659 0.341 0.000
G61 Inflammatory polyneuropathy
0.659 0.341 0.000
F33.9 Recurrent depressive disorder, unspecified
0.659 0.341 0.000
F10.1 Harmful use
0.659 0.341 0.000
H61 Other disorders of external ear
0.659 0.341 0.000
I88 Nonspecific lymphadenitis
0.659 0.341 0.000
A41.8 Other specified septicaemia
0.658 0.342 0.000
I60 Subarachnoid haemorrhage
0.657 0.343 0.000
K65 Peritonitis
0.656 0.344 0.000
K81 Cholecystitis
0.655 0.345 0.000
N48.1 Balanoposthitis
0.655 0.345 0.000
M79.6 Pain in limb
0.654 0.346 0.000
M34.8 Other forms of systemic sclerosis
0.653 0.347 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.653 0.347 0.000
M34.0 Progressive systemic sclerosis
0.653 0.347 0.000
G95 Other diseases of spinal cord
0.653 0.347 0.000
F31.8 Other bipolar affective disorders
0.652 0.348 0.000
F31.7 Bipolar affective disorder, currently in remission
0.652 0.348 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.652 0.348 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.652 0.348 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.652 0.348 0.000
Y45.1 Salicylates
0.652 0.348 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.652 0.348 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.651 0.348 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.651 0.348 0.000
Y98 Lifestyle-related condition
0.651 0.348 0.000
Y97 Environmental-pollution-related condition
0.651 0.348 0.000
Y96 Work-related condition
0.651 0.348 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.651 0.349 0.000
M31.6 Other giant cell arteritis
0.651 0.349 0.000
H18 Other disorders of cornea
0.651 0.349 0.000
K83.9 Disease of biliary tract, unspecified
0.649 0.350 0.000
K83.5 Biliary cyst
0.649 0.350 0.000
K83.4 Spasm of sphincter of Oddi
0.649 0.350 0.000
K83.3 Fistula of bile duct
0.649 0.350 0.000
K83.2 Perforation of bile duct
0.649 0.350 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.649 0.351 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.649 0.351 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.649 0.351 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.647 0.353 0.000
D67 Hereditary factor IX deficiency
0.647 0.353 0.000
D66 Hereditary factor VIII deficiency
0.647 0.353 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.647 0.353 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.647 0.353 0.000
Q80-Q89 Other congenital malformations
0.647 0.353 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.647 0.353 0.000
Q35-Q37 Cleft lip and cleft palate
0.647 0.353 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.647 0.353 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.647 0.353 0.000
Q00-Q07 Congenital malformations of the nervous system
0.647 0.353 0.000
K75.9 Inflammatory liver disease, unspecified
0.647 0.353 0.000
K29.4 Chronic atrophic gastritis
0.646 0.354 0.000
M21.3 Wrist or foot drop (acquired)
0.646 0.354 0.000
A49.3 Mycoplasma infection, unspecified
0.645 0.355 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.645 0.355 0.000
A49.1 Streptococcal infection, unspecified
0.645 0.355 0.000
M25.9 Joint disorder, unspecified
0.645 0.355 0.000
M25.3 Other instability of joint
0.645 0.355 0.000
M25.2 Flail joint
0.645 0.355 0.000
M25.1 Fistula of joint
0.645 0.355 0.000
M25.0 Haemarthrosis
0.645 0.355 0.000
N50.8 Other specified disorders of male genital organs
0.644 0.356 0.000
I99 Other and unspecified disorders of circulatory system
0.644 0.356 0.000
T98 Sequelae of other and unspecified effects of external causes
0.644 0.356 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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