TreeWAS – Variant ID: rs80150070

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
J40-J47 Chronic lower respiratory diseases	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
# Top node	1.000	0.000
Chapter V Mental and behavioural disorders	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
J45 Asthma	1.000	0.000
J45.9 Asthma, unspecified	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
M80-M85 Disorders of bone density and structure	0.999	0.001
R50-R69 General symptoms and signs	0.999	0.001
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.999	0.001
M81 Osteoporosis without pathological fracture	0.999	0.001
M81.9 Osteoporosis, unspecified	0.999	0.001
M81.99 Osteoporosis, unspecified (Site unspecified)	0.998	0.002
T36-T50 Poisoning by drugs, medicaments and biological substances	0.997	0.003
M70-M79 Other soft tissue disorders	0.996	0.004
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.995	0.005
Chapter IV Endocrine, nutritional and metabolic diseases	0.994	0.006
Chapter VIII Diseases of the ear and mastoid process	0.993	0.007
J44 Other chronic obstructive pulmonary disease	0.992	0.008
M75 Shoulder lesions	0.990	0.010
F10 Mental and behavioural disorders due to use of alcohol	0.989	0.011
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.988	0.012
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.986	0.014
F17 Mental and behavioural disorders due to use of tobacco	0.982	0.018
R63 Symptoms and signs concerning food and fluid intake	0.982	0.018
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.980	0.020
F30-F39 Mood [affective] disorders	0.980	0.020
E70-E90 Metabolic disorders	0.978	0.022
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.971	0.029
F17.1 Harmful use	0.970	0.030
E86 Volume depletion	0.967	0.033
T84.1 Mechanical complication of internal fixation device of bones of limb	0.966	0.034
Chapter I Certain infectious and parasitic diseases	0.964	0.036
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.964	0.036
T43.0 Tricyclic and tetracyclic antidepressants	0.963	0.037
Chapter XI Diseases of the digestive system	0.960	0.040
R63.4 Abnormal weight loss	0.960	0.040
R51 Headache	0.959	0.041
Chapter VI Diseases of the nervous system	0.958	0.042
R11 Nausea and vomiting	0.953	0.047
F10.2 Dependence syndrome	0.951	0.049
S20-S29 Injuries to the thorax	0.948	0.052
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.946	0.054
K70-K77 Diseases of liver	0.944	0.056
S60-S69 Injuries to the wrist and hand	0.943	0.057
R60 Oedema, not elsewhere classified	0.939	0.061
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.936	0.064
H80-H83 Diseases of inner ear	0.936	0.064
H60-H62 Diseases of external ear	0.932	0.068
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.930	0.070
F32 Depressive episode	0.926	0.074
M75.5 Bursitis of shoulder	0.926	0.074
Chapter IX Diseases of the circulatory system	0.924	0.076
K11 Diseases of salivary glands	0.924	0.076
F60-F69 Disorders of adult personality and behaviour	0.921	0.079
J80-J84 Other respiratory diseases principally affecting the interstitium	0.921	0.079
I60-I69 Cerebrovascular diseases	0.916	0.084
R55 Syncope and collapse	0.914	0.086
M75.3 Calcific tendinitis of shoulder	0.912	0.088
B95-B98 Bacterial, viral and other infectious agents	0.911	0.089
J30-J39 Other diseases of upper respiratory tract	0.911	0.089
S22 Fracture of rib(s), sternum and thoracic spine	0.906	0.094
K70 Alcoholic liver disease	0.905	0.095
G80-G83 Cerebral palsy and other paralytic syndromes	0.905	0.095
H90-H95 Other disorders of ear	0.903	0.097
T51 Toxic effect of alcohol	0.901	0.099
K11.2 Sialoadenitis	0.896	0.104
F10.0 Acute intoxication	0.895	0.105
R10 Abdominal and pelvic pain	0.892	0.108
M81.98 Osteoporosis, unspecified (Other)	0.892	0.108
T43.2 Other and unspecified antidepressants	0.891	0.109
I10-I15 Hypertensive diseases	0.890	0.110
J90-J94 Other diseases of pleura	0.885	0.115
J45.0 Predominantly allergic asthma	0.884	0.116
I12 Hypertensive renal disease	0.884	0.116
E80 Disorders of porphyrin and bilirubin metabolism	0.882	0.118
I67 Other cerebrovascular diseases	0.880	0.120
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.879	0.121
R14 Flatulence and related conditions	0.876	0.124
T20-T25 Burns and corrosions of external body surface, specified by site	0.874	0.126
R42 Dizziness and giddiness	0.870	0.130
S64 Injury of nerves at wrist and hand level	0.870	0.130
I12.0 Hypertensive renal disease with renal failure	0.869	0.131
G81 Hemiplegia	0.868	0.132
F32.9 Depressive episode, unspecified	0.868	0.132
F60 Specific personality disorders	0.864	0.136
R41 Other symptoms and signs involving cognitive functions and awareness	0.864	0.136
F32.1 Moderate depressive episode	0.862	0.138
R10.4 Other and unspecified abdominal pain	0.861	0.139
H83 Other diseases of inner ear	0.861	0.139
M70 Soft tissue disorders related to use, overuse and pressure	0.861	0.139
B35-B49 Mycoses	0.856	0.144
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.856	0.144
M75.4 Impingement syndrome of shoulder	0.853	0.147
H61 Other disorders of external ear	0.852	0.148
K11.5 Sialolithiasis	0.851	0.149
R59 Enlarged lymph nodes	0.849	0.151
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.848	0.152
T51.0 Ethanol	0.847	0.153
E40-E46 Malnutrition	0.846	0.154
M81.90 Osteoporosis, unspecified (Multiple sites)	0.845	0.155
Chapter XXI Factors influencing health status and contact with health services	0.845	0.155
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.844	0.156
S22.4 Multiple fractures of ribs	0.844	0.156
J09-J18 Influenza and pneumonia	0.844	0.156
G81.9 Hemiplegia, unspecified	0.843	0.157
F40-F48 Neurotic, stress-related and somatoform disorders	0.842	0.157
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.841	0.159
R60.0 Localised oedema	0.838	0.162
F31 Bipolar affective disorder	0.836	0.164
E50-E64 Other nutritional deficiencies	0.833	0.167
K76 Other diseases of liver	0.831	0.169
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.831	0.169
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.830	0.170
M75.9 Shoulder lesion, unspecified	0.829	0.171
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.828	0.172
G40-G47 Episodic and paroxysmal disorders	0.828	0.172
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.828	0.172
Z60 Problems related to social environment	0.828	0.172
M77 Other enthesopathies	0.827	0.173
R60.9 Oedema, unspecified	0.826	0.174
K04 Diseases of pulp and periapical tissues	0.825	0.175
J81 Pulmonary oedema	0.824	0.176
J33 Nasal polyp	0.823	0.177
R46 Symptoms and signs involving appearance and behaviour	0.822	0.178
Chapter XII Diseases of the skin and subcutaneous tissue	0.821	0.179
J30 Vasomotor and allergic rhinitis	0.820	0.180
Z60.2 Living alone	0.818	0.182
G20-G26 Extrapyramidal and movement disorders	0.818	0.182
F10.1 Harmful use	0.817	0.183
J95-J99 Other diseases of the respiratory system	0.815	0.185
T86 Failure and rejection of transplanted organs and tissues	0.815	0.185
E80.4 Gilbert's syndrome	0.814	0.186
T84.0 Mechanical complication of internal joint prosthesis	0.813	0.187
I60 Subarachnoid haemorrhage	0.812	0.188
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.810	0.190
F34 Persistent mood [affective] disorders	0.810	0.190
I67.8 Other specified cerebrovascular diseases	0.810	0.190
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.810	0.190
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.809	0.191
H83.0 Labyrinthitis	0.808	0.192
M60-M63 Disorders of muscles	0.807	0.193
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.806	0.194
K76.0 Fatty (change of) liver, not elsewhere classified	0.806	0.194
K70.9 Alcoholic liver disease, unspecified	0.806	0.194
J46 Status asthmaticus	0.805	0.195
J42 Unspecified chronic bronchitis	0.804	0.196
I12.9 Hypertensive renal disease without renal failure	0.803	0.197
S22.0 Fracture of thoracic vertebra	0.801	0.199
R50 Fever of unknown origin	0.800	0.200
S22.40 Multiple fractures of ribs (closed)	0.800	0.200
R59.0 Localised enlarged lymph nodes	0.800	0.200
R63.5 Abnormal weight gain	0.798	0.202
T66-T78 Other and unspecified effects of external causes	0.798	0.202
H90 Conductive and sensorineural hearing loss	0.797	0.203
M20-M25 Other joint disorders	0.796	0.204
I67.9 Cerebrovascular disease, unspecified	0.794	0.206
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.794	0.206
S66 Injury of muscle and tendon at wrist and hand level	0.793	0.207
S64.4 Injury of digital nerve of other finger	0.792	0.208
J84 Other interstitial pulmonary diseases	0.790	0.210
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.790	0.210
J33.9 Nasal polyp, unspecified	0.789	0.211
M05-M14 Inflammatory polyarthropathies	0.789	0.211
S60 Superficial injury of wrist and hand	0.788	0.212
H60 Otitis externa	0.788	0.212
R58 Haemorrhage, not elsewhere classified	0.787	0.213
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.786	0.214
T82.4 Mechanical complication of vascular dialysis catheter	0.784	0.216
H61.0 Perichondritis of external ear	0.784	0.216
H80 Otosclerosis	0.783	0.217
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.783	0.217
F60.9 Personality disorder, unspecified	0.782	0.218
K06 Other disorders of gingiva and edentulous alveolar ridge	0.782	0.218
K70.3 Alcoholic cirrhosis of liver	0.782	0.218
S80-S89 Injuries to the knee and lower leg	0.780	0.220
G47 Sleep disorders	0.779	0.221
K90-K93 Other diseases of the digestive system	0.778	0.222
F10.3 Withdrawal state	0.777	0.223
R63.0 Anorexia	0.775	0.225
R53 Malaise and fatigue	0.772	0.228
Z63 Other problems related to primary support group, including family circumstances	0.771	0.229
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.771	0.229
G35-G37 Demyelinating diseases of the central nervous system	0.768	0.232
M81.4 Drug-induced osteoporosis	0.766	0.234
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.766	0.234
T80 Complications following infusion, transfusion and therapeutic injection	0.764	0.236
B20-B24 Human immunodeficiency virus [HIV] disease	0.764	0.236
M50-M54 Other dorsopathies	0.762	0.238
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.760	0.240
K72 Hepatic failure, not elsewhere classified	0.759	0.241
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.759	0.241
Chapter VII Diseases of the eye and adnexa	0.758	0.242
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.758	0.242
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.757	0.243
J90 Pleural effusion, not elsewhere classified	0.756	0.244
G70-G73 Diseases of myoneural junction and muscle	0.756	0.244
T87 Complications peculiar to reattachment and amputation	0.755	0.244
I61 Intracerebral haemorrhage	0.754	0.246
R44 Other symptoms and signs involving general sensations and perceptions	0.752	0.248
R10.0 Acute abdomen	0.752	0.248
M75.2 Bicipital tendinitis	0.752	0.248
M86-M90 Other osteopathies	0.751	0.249
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.749	0.251
T46 Poisoning by agents primarily affecting the cardiovascular system	0.749	0.251
F41 Other anxiety disorders	0.748	0.252
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.747	0.253
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.747	0.253
T51.9 Alcohol, unspecified	0.747	0.253
B35 Dermatophytosis	0.746	0.254
M75.0 Adhesive capsulitis of shoulder	0.746	0.254
F60.3 Emotionally unstable personality disorder	0.743	0.257
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.743	0.257
T59 Toxic effect of other gases, fumes and vapours	0.742	0.258
R57 Shock, not elsewhere classified	0.741	0.259
F33 Recurrent depressive disorder	0.740	0.259
A30-A49 Other bacterial diseases	0.740	0.260
G90-G99 Other disorders of the nervous system	0.740	0.260
E46 Unspecified protein-energy malnutrition	0.739	0.261
J15 Bacterial pneumonia, not elsewhere classified	0.739	0.261
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.737	0.263
S65 Injury of blood vessels at wrist and hand level	0.736	0.263
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.736	0.264
S90-S99 Injuries to the ankle and foot	0.736	0.264
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.735	0.265
F80-F89 Disorders of psychological development	0.734	0.266
J13 Pneumonia due to Streptococcus pneumoniae	0.732	0.268
I62 Other nontraumatic intracranial haemorrhage	0.732	0.268
F31.9 Bipolar affective disorder, unspecified	0.732	0.268
M82 Osteoporosis in diseases classified elsewhere	0.732	0.268
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.731	0.269
M70.6 Trochanteric bursitis	0.731	0.269
R63.1 Polydipsia	0.731	0.269
T15-T19 Effects of foreign body entering through natural orifice	0.729	0.271
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.729	0.271
S20 Superficial injury of thorax	0.729	0.271
I63 Cerebral infarction	0.728	0.272
H30-H36 Disorders of choroid and retina	0.728	0.272
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.727	0.273
E00-E07 Disorders of thyroid gland	0.726	0.274
S22.00 Fracture of thoracic vertebra (closed)	0.725	0.275
T82.0 Mechanical complication of heart valve prosthesis	0.725	0.275
H93 Other disorders of ear, not elsewhere classified	0.725	0.275
S50-S59 Injuries to the elbow and forearm	0.725	0.275
F17.2 Dependence syndrome	0.725	0.275
J40 Bronchitis, not specified as acute or chronic	0.722	0.278
T23 Burn and corrosion of wrist and hand	0.721	0.279
K70.1 Alcoholic hepatitis	0.721	0.279
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.719	0.281
M85 Other disorders of bone density and structure	0.719	0.281
J41 Simple and mucopurulent chronic bronchitis	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.717	0.283
F70-F79 Mental retardation	0.717	0.283
J45.8 Mixed asthma	0.717	0.283
J45.1 Nonallergic asthma	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
M83 Adult osteomalacia	0.716	0.283
R62 Lack of expected normal physiological development	0.716	0.284
R64 Cachexia	0.716	0.284
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.716	0.284
F18 Mental and behavioural disorders due to use of volatile solvents	0.716	0.284
F16 Mental and behavioural disorders due to use of hallucinogens	0.716	0.284
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.716	0.284
F14 Mental and behavioural disorders due to use of cocaine	0.716	0.284
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.716	0.284
F11 Mental and behavioural disorders due to use of opioids	0.716	0.284
M81.8 Other osteoporosis	0.716	0.284
M81.6 Localised osteoporosis [Lequesne]	0.716	0.284
M81.5 Idiopathic osteoporosis	0.716	0.284
M81.3 Postsurgical malabsorption osteoporosis	0.716	0.284
M81.2 Osteoporosis of disuse	0.716	0.284
M81.1 Postoophorectomy osteoporosis	0.716	0.284
M81.0 Postmenopausal osteoporosis	0.716	0.284
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.716	0.284
M81.96 Osteoporosis, unspecified (Lower leg)	0.716	0.284
M81.94 Osteoporosis, unspecified (Hand)	0.716	0.284
M81.93 Osteoporosis, unspecified (Forearm)	0.716	0.284
M81.92 Osteoporosis, unspecified (Upper arm)	0.716	0.284
M81.91 Osteoporosis, unspecified (Shoulder region)	0.716	0.284
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.715	0.285
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.715	0.285
T41 Poisoning by anaesthetics and therapeutic gases	0.715	0.285
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.715	0.285
T36 Poisoning by systemic antibiotics	0.715	0.285
L20-L30 Dermatitis and eczema	0.715	0.285
E87 Other disorders of fluid, electrolyte and acid-base balance	0.715	0.285
M76 Enthesopathies of lower limb, excluding foot	0.714	0.286
M73 Soft tissue disorders in diseases classified elsewhere	0.714	0.286
B65-B83 Helminthiases	0.714	0.286
E16 Other disorders of pancreatic internal secretion	0.713	0.287
M25 Other joint disorders, not elsewhere classified	0.713	0.287
E65-E68 Obesity and other hyperalimentation	0.712	0.288
T79-T79 Certain early complications of trauma	0.712	0.288
S10-S19 Injuries to the neck	0.712	0.288
Z70-Z76 Persons encountering health services in other circumstances	0.712	0.288
K74 Fibrosis and cirrhosis of liver	0.711	0.289
S40-S49 Injuries to the shoulder and upper arm	0.710	0.290
M75.8 Other shoulder lesions	0.710	0.290
S62 Fracture at wrist and hand level	0.710	0.290
F10.9 Unspecified mental and behavioural disorder	0.709	0.291
F10.8 Other mental and behavioural disorders	0.709	0.291
F10.7 Residual and late-onset psychotic disorder	0.709	0.291
F10.6 Amnesic syndrome	0.709	0.291
F10.5 Psychotic disorder	0.709	0.291
T82.1 Mechanical complication of cardiac electronic device	0.709	0.291
K05 Gingivitis and periodontal diseases	0.709	0.291
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.708	0.292
M91-M94 Chondropathies	0.708	0.292
H91 Other hearing loss	0.707	0.293
E61 Deficiency of other nutrient elements	0.707	0.293
L00-L08 Infections of the skin and subcutaneous tissue	0.707	0.293
T43.9 Psychotropic drug, unspecified	0.707	0.293
T43.8 Other psychotropic drugs, not elsewhere classified	0.707	0.293
T43.6 Psychostimulants with abuse potential	0.707	0.293
T43.4 Butyrophenone and thioxanthene neuroleptics	0.707	0.293
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.707	0.293
I05-I09 Chronic rheumatic heart diseases	0.707	0.293
Chapter XXII Codes for special purposes	0.706	0.293
S64.3 Injury of digital nerve of thumb	0.705	0.295
F17.9 Unspecified mental and behavioural disorder	0.704	0.296
F17.8 Other mental and behavioural disorders	0.704	0.296
F17.7 Residual and late-onset psychotic disorder	0.704	0.296
F17.6 Amnesic syndrome	0.704	0.296
F17.5 Psychotic disorder	0.704	0.296
F17.4 Withdrawal state with delirium	0.704	0.296
F17.3 Withdrawal state	0.704	0.296
F17.0 Acute intoxication	0.704	0.296
R63.6 Insufficient intake of food and water due to self neglect	0.704	0.296
R63.3 Feeding difficulties and mismanagement	0.704	0.296
R63.2 Polyphagia	0.704	0.296
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.704	0.296
M00-M03 Infectious arthropathies	0.704	0.296
J92 Pleural plaque	0.704	0.296
G20 Parkinson's disease	0.703	0.297
S27 Injury of other and unspecified intrathoracic organs	0.703	0.297
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.702	0.297
F38 Other mood [affective] disorders	0.702	0.298
F30 Manic episode	0.702	0.298
F39 Unspecified mood [affective] disorder	0.702	0.298
J91 Pleural effusion in conditions classified elsewhere	0.702	0.298
E88 Other metabolic disorders	0.701	0.299
E85 Amyloidosis	0.701	0.299
E84 Cystic fibrosis	0.701	0.299
E79 Disorders of purine and pyrimidine metabolism	0.701	0.299
E77 Disorders of glycoprotein metabolism	0.701	0.299
E76 Disorders of glycosaminoglycan metabolism	0.701	0.299
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.701	0.299
E74 Other disorders of carbohydrate metabolism	0.701	0.299
E73 Lactose intolerance	0.701	0.299
E72 Other disorders of amino-acid metabolism	0.701	0.299
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.701	0.299
E70 Disorders of aromatic amino-acid metabolism	0.701	0.299
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.701	0.299
R10.1 Pain localised to upper abdomen	0.701	0.299
R40 Somnolence, stupor and coma	0.700	0.300
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.700	0.300
R41.0 Disorientation, unspecified	0.700	0.300
M80 Osteoporosis with pathological fracture	0.699	0.301
T43.5 Other and unspecified antipsychotics and neuroleptics	0.698	0.302
K70.4 Alcoholic hepatic failure	0.698	0.302
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.697	0.303
G47.3 Sleep apnoea	0.697	0.303
R43 Disturbances of smell and taste	0.696	0.304
F12 Mental and behavioural disorders due to use of cannabinoids	0.696	0.304
R41.2 Retrograde amnesia	0.696	0.304
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.696	0.304
M71 Other bursopathies	0.696	0.304
J30.3 Other allergic rhinitis	0.696	0.304
J39 Other diseases of upper respiratory tract	0.695	0.305
T43.3 Phenothiazine antipsychotics and neuroleptics	0.695	0.305
S61 Open wound of wrist and hand	0.695	0.305
E20-E35 Disorders of other endocrine glands	0.694	0.306
J38.7 Other diseases of larynx	0.693	0.307
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.692	0.308
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.692	0.308
B99-B99 Other infectious diseases	0.691	0.309
B85-B89 Pediculosis, acariasis and other infestations	0.691	0.309
B50-B64 Protozoal diseases	0.691	0.309
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.691	0.309
A75-A79 Rickettsioses	0.691	0.309
A70-A74 Other diseases caused by chlamydiae	0.691	0.309
A65-A69 Other spirochaetal diseases	0.691	0.309
A20-A28 Certain zoonotic bacterial diseases	0.691	0.309
A15-A19 Tuberculosis	0.691	0.309
A80-A89 Viral infections of the central nervous system	0.691	0.309
J47 Bronchiectasis	0.691	0.309
S60.8 Other superficial injuries of wrist and hand	0.691	0.309
K04.8 Radicular cyst	0.689	0.311
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.689	0.311
K65-K67 Diseases of peritoneum	0.689	0.311
R54 Senility	0.688	0.312
F34.1 Dysthymia	0.688	0.312
R50.0 Fever with chills	0.688	0.312
K12 Stomatitis and related lesions	0.687	0.313
J14 Pneumonia due to Haemophilus influenzae	0.687	0.313
T86.8 Failure and rejection of other transplanted organs and tissues	0.686	0.314
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.686	0.314
H81 Disorders of vestibular function	0.685	0.315
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.684	0.316
M79 Other soft tissue disorders, not elsewhere classified	0.684	0.316
F99-F99 Unspecified mental disorder	0.684	0.316
J94 Other pleural conditions	0.684	0.316
S22.1 Multiple fractures of thoracic spine	0.683	0.317
R46.8 Other symptoms and signs involving appearance and behaviour	0.682	0.318
R41.3 Other amnesia	0.680	0.320
K04.5 Chronic apical periodontitis	0.680	0.320
M70.4 Prepatellar bursitis	0.680	0.320
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.680	0.320
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.679	0.320
S26 Injury of heart	0.679	0.320
S25 Injury of blood vessels of thorax	0.679	0.320
S24 Injury of nerves and spinal cord at thorax level	0.679	0.320
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.679	0.320
S21 Open wound of thorax	0.679	0.320
A00-A09 Intestinal infectious diseases	0.679	0.321
T65 Toxic effect of other and unspecified substances	0.678	0.322
T62 Toxic effect of other noxious substances eaten as food	0.678	0.322
T61 Toxic effect of noxious substances eaten as seafood	0.678	0.322
T60 Toxic effect of pesticides	0.678	0.322
T57 Toxic effect of other inorganic substances	0.678	0.322
T56 Toxic effect of metals	0.678	0.322
T54 Toxic effect of corrosive substances	0.678	0.322
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.678	0.322
T52 Toxic effect of organic solvents	0.678	0.322
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.678	0.322
T58 Toxic effect of carbon monoxide	0.678	0.322
T55 Toxic effect of soaps and detergents	0.678	0.322
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.678	0.322
M06 Other rheumatoid arthritis	0.678	0.322
S81 Open wound of lower leg	0.677	0.323
K77 Liver disorders in diseases classified elsewhere	0.677	0.323
K73 Chronic hepatitis, not elsewhere classified	0.677	0.323
K71 Toxic liver disease	0.677	0.323
K07 Dentofacial anomalies [including malocclusion]	0.676	0.324
Z58 Problems related to physical environment	0.676	0.324
T45.0 Antiallergic and antiemetic drugs	0.675	0.325
G83 Other paralytic syndromes	0.675	0.325
R65.1 Systemic Inflammatory Response Syndrome of infectious origin with organ failure	0.675	0.325
Z63.4 Disappearance and death of family member	0.674	0.326
H80.9 Otosclerosis, unspecified	0.674	0.326
R60.1 Generalised oedema	0.673	0.326
B44 Aspergillosis	0.673	0.327
T82.3 Mechanical complication of other vascular grafts	0.673	0.327
F43 Reaction to severe stress, and adjustment disorders	0.673	0.327
M31 Other necrotising vasculopathies	0.673	0.327
K14 Diseases of tongue	0.673	0.327
J35 Chronic diseases of tonsils and adenoids	0.672	0.327
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.672	0.328
K03 Other diseases of hard tissues of teeth	0.671	0.329
H82 Vertiginous syndromes in diseases classified elsewhere	0.671	0.329
J44.8 Other specified chronic obstructive pulmonary disease	0.671	0.329
G45 Transient cerebral ischaemic attacks and related syndromes	0.670	0.330
G44 Other headache syndromes	0.670	0.330
M24 Other specific joint derangements	0.670	0.330
H33 Retinal detachments and breaks	0.669	0.331
M62 Other disorders of muscle	0.668	0.332
H62 Disorders of external ear in diseases classified elsewhere	0.668	0.332
R13 Dysphagia	0.668	0.332
M77.1 Lateral epicondylitis	0.668	0.332
B35.3 Tinea pedis	0.668	0.332
T94 Sequelae of injuries involving multiple and unspecified body regions	0.667	0.333
T84.3 Mechanical complication of other bone devices, implants and grafts	0.667	0.333
M40-M43 Deforming dorsopathies	0.667	0.333
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.666	0.333
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.666	0.333
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.666	0.334
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.666	0.334
G47.9 Sleep disorder, unspecified	0.666	0.334
T20 Burn and corrosion of head and neck	0.666	0.334
E55 Vitamin D deficiency	0.665	0.334
J98 Other respiratory disorders	0.665	0.335
F32.8 Other depressive episodes	0.664	0.336
H60.1 Cellulitis of external ear	0.664	0.336
M77.0 Medial epicondylitis	0.663	0.337
T93 Sequelae of injuries of lower limb	0.663	0.337
I00-I02 Acute rheumatic fever	0.663	0.337
K11.8 Other diseases of salivary glands	0.662	0.337
K11.7 Disturbances of salivary secretion	0.662	0.337
K11.4 Fistula of salivary gland	0.662	0.337
K11.3 Abscess of salivary gland	0.662	0.337
K11.0 Atrophy of salivary gland	0.662	0.337
J30.4 Allergic rhinitis, unspecified	0.662	0.338
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.661	0.338
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.661	0.339
F68 Other disorders of adult personality and behaviour	0.660	0.340
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.660	0.340
F65 Disorders of sexual preference	0.660	0.340
F64 Gender identity disorders	0.660	0.340
F63 Habit and impulse disorders	0.660	0.340
F62 Enduring personality changes, not attributable to brain damage and disease	0.660	0.340
F69 Unspecified disorder of adult personality and behaviour	0.660	0.340
F61 Mixed and other personality disorders	0.660	0.340
J82 Pulmonary eosinophilia, not elsewhere classified	0.660	0.340
E83 Disorders of mineral metabolism	0.659	0.341

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations