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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80167425
log Bayes Factor = 13.1983
Chromosome 16   position 55,715,542  (GRCh37) Explore rs80167425 on Ensembl!
Variant rs80167425 is part of Cluster X0261

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.996 0.004 0.000
I50 Heart failure
0.995 0.005 0.000
I47 Paroxysmal tachycardia
0.990 0.010 0.000
J40-J47 Chronic lower respiratory diseases
0.986 0.014 0.000
I25.1 Atherosclerotic heart disease
0.983 0.017 0.000
I20 Angina pectoris
0.983 0.017 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.982 0.018 0.000
I47.1 Supraventricular tachycardia
0.981 0.019 0.000
M05-M14 Inflammatory polyarthropathies
0.978 0.022 0.000
I25.2 Old myocardial infarction
0.976 0.024 0.000
M06 Other rheumatoid arthritis
0.975 0.025 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.974 0.026 0.000
M06.9 Rheumatoid arthritis, unspecified
0.970 0.030 0.000
I50.1 Left ventricular failure
0.965 0.035 0.000
I34 Nonrheumatic mitral valve disorders
0.965 0.035 0.000
S70-S79 Injuries to the hip and thigh
0.958 0.042 0.000
I22 Subsequent myocardial infarction
0.952 0.048 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.950 0.050 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.946 0.054 0.000
J47 Bronchiectasis
0.946 0.054 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.946 0.054 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.941 0.059 0.000
R30-R39 Symptoms and signs involving the urinary system
0.940 0.060 0.000
I42 Cardiomyopathy
0.939 0.061 0.000
J43 Emphysema
0.935 0.065 0.000
R35 Polyuria
0.935 0.065 0.000
Chapter XXII Codes for special purposes
0.934 0.066 0.000
S50-S59 Injuries to the elbow and forearm
0.932 0.068 0.000
I20.8 Other forms of angina pectoris
0.927 0.073 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.926 0.074 0.000
I50.0 Congestive heart failure
0.921 0.079 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.920 0.080 0.000
J20-J22 Other acute lower respiratory infections
0.916 0.084 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.912 0.088 0.000
J44 Other chronic obstructive pulmonary disease
0.906 0.094 0.000
M80-M85 Disorders of bone density and structure
0.902 0.098 0.000
J95-J99 Other diseases of the respiratory system
0.901 0.099 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.898 0.102 0.000
I44 Atrioventricular and left bundle-branch block
0.896 0.104 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.894 0.106 0.000
I38 Endocarditis, valve unspecified
0.889 0.111 0.000
J43.9 Emphysema, unspecified
0.883 0.117 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.883 0.117 0.000
I34.0 Mitral (valve) insufficiency
0.881 0.119 0.000
M45-M49 Spondylopathies
0.881 0.119 0.000
I24 Other acute ischaemic heart diseases
0.879 0.121 0.000
I05-I09 Chronic rheumatic heart diseases
0.878 0.122 0.000
I20.0 Unstable angina
0.875 0.125 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.875 0.125 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.874 0.125 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.873 0.127 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.868 0.132 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.866 0.134 0.000
S70 Superficial injury of hip and thigh
0.865 0.135 0.000
I50.9 Heart failure, unspecified
0.865 0.135 0.000
R32 Unspecified urinary incontinence
0.859 0.141 0.000
J22 Unspecified acute lower respiratory infection
0.859 0.141 0.000
E70-E90 Metabolic disorders
0.856 0.144 0.000
I42.9 Cardiomyopathy, unspecified
0.855 0.145 0.000
I49 Other cardiac arrhythmias
0.853 0.147 0.000
I35 Nonrheumatic aortic valve disorders
0.852 0.148 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.845 0.155 0.000
I25.3 Aneurysm of heart
0.844 0.156 0.000
I20.9 Angina pectoris, unspecified
0.843 0.157 0.000
S52 Fracture of forearm
0.834 0.166 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.833 0.167 0.000
I34.1 Mitral (valve) prolapse
0.827 0.173 0.000
I44.0 Atrioventricular block, first degree
0.821 0.179 0.000
I27 Other pulmonary heart diseases
0.821 0.179 0.000
S51 Open wound of forearm
0.821 0.179 0.000
J98 Other respiratory disorders
0.818 0.182 0.000
U80 Agent resistant to penicillin and related antibiotics
0.818 0.182 0.000
R07 Pain in throat and chest
0.814 0.186 0.000
E20-E35 Disorders of other endocrine glands
0.814 0.186 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.814 0.186 0.000
Q23 Congenital malformations of aortic and mitral valves
0.812 0.188 0.000
R30 Pain associated with micturition
0.812 0.188 0.000
I49.8 Other specified cardiac arrhythmias
0.811 0.189 0.000
R47-R49 Symptoms and signs involving speech and voice
0.810 0.190 0.000
M45 Ankylosing spondylitis
0.809 0.191 0.000
Q21 Congenital malformations of cardiac septa
0.808 0.192 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.806 0.194 0.000
J09-J18 Influenza and pneumonia
0.806 0.194 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.803 0.197 0.000
S79 Other and unspecified injuries of hip and thigh
0.802 0.198 0.000
Chapter XX External causes of morbidity and mortality
0.801 0.199 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.800 0.200 0.000
M06.0 Seronegative rheumatoid arthritis
0.799 0.201 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.799 0.201 0.000
R04 Haemorrhage from respiratory passages
0.799 0.201 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.796 0.203 0.000
I45 Other conduction disorders
0.796 0.203 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.796 0.204 0.000
R07.4 Chest pain, unspecified
0.795 0.205 0.000
J90-J94 Other diseases of pleura
0.794 0.206 0.000
J60-J70 Lung diseases due to external agents
0.793 0.206 0.000
M85 Other disorders of bone density and structure
0.792 0.207 0.000
J98.1 Pulmonary collapse
0.789 0.211 0.000
I24.8 Other forms of acute ischaemic heart disease
0.789 0.211 0.000
S90-S99 Injuries to the ankle and foot
0.786 0.214 0.000
I44.1 Atrioventricular block, second degree
0.783 0.217 0.000
S72 Fracture of femur
0.783 0.217 0.000
S32 Fracture of lumbar spine and pelvis
0.783 0.217 0.000
I33 Acute and subacute endocarditis
0.782 0.218 0.000
Chapter VII Diseases of the eye and adnexa
0.782 0.218 0.000
J40 Bronchitis, not specified as acute or chronic
0.781 0.219 0.000
I42.8 Other cardiomyopathies
0.780 0.220 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.780 0.220 0.000
Q50-Q56 Congenital malformations of genital organs
0.777 0.223 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.777 0.223 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.774 0.226 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.772 0.228 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.769 0.231 0.000
R06 Abnormalities of breathing
0.767 0.233 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.765 0.234 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.763 0.237 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.763 0.237 0.000
M07 Psoriatic and enteropathic arthropathies
0.761 0.239 0.000
M86-M90 Other osteopathies
0.761 0.239 0.000
I27.2 Other secondary pulmonary hypertension
0.760 0.240 0.000
M65-M68 Disorders of synovium and tendon
0.760 0.240 0.000
U80.1 Methicillin resistant agent
0.759 0.241 0.000
E00-E07 Disorders of thyroid gland
0.759 0.241 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.758 0.242 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.758 0.242 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.758 0.242 0.000
I31 Other diseases of pericardium
0.757 0.243 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.757 0.243 0.000
M05 Seropositive rheumatoid arthritis
0.756 0.244 0.000
Q80-Q89 Other congenital malformations
0.755 0.245 0.000
I07 Rheumatic tricuspid valve diseases
0.755 0.245 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.755 0.245 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.754 0.246 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.753 0.247 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.752 0.248 0.000
M06.4 Inflammatory polyarthropathy
0.750 0.250 0.000
R04.2 Haemoptysis
0.749 0.251 0.000
E87.6 Hypokalaemia
0.749 0.251 0.000
E87.2 Acidosis
0.746 0.254 0.000
J43.2 Centrilobular emphysema
0.746 0.254 0.000
R47 Speech disturbances, not elsewhere classified
0.744 0.256 0.000
S71 Open wound of hip and thigh
0.741 0.259 0.000
E50-E64 Other nutritional deficiencies
0.740 0.260 0.000
R30.0 Dysuria
0.735 0.265 0.000
E40-E46 Malnutrition
0.735 0.265 0.000
S80-S89 Injuries to the knee and lower leg
0.735 0.265 0.000
Q27 Other congenital malformations of peripheral vascular system
0.732 0.268 0.000
Q23.1 Congenital insufficiency of aortic valve
0.731 0.269 0.000
R06.0 Dyspnoea
0.731 0.269 0.000
I26 Pulmonary embolism
0.730 0.270 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.729 0.271 0.000
I22.8 Subsequent myocardial infarction of other sites
0.729 0.271 0.000
I42.6 Alcoholic cardiomyopathy
0.728 0.272 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.727 0.273 0.000
I51 Complications and ill-defined descriptions of heart disease
0.725 0.275 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.724 0.276 0.000
Q21.1 Atrial septal defect
0.723 0.277 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.723 0.277 0.000
I25.5 Ischaemic cardiomyopathy
0.723 0.277 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.722 0.277 0.000
I36 Nonrheumatic tricuspid valve disorders
0.722 0.278 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.720 0.280 0.000
I49.3 Ventricular premature depolarisation
0.720 0.280 0.000
M84 Disorders of continuity of bone
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.717 0.283 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.285 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.714 0.286 0.000
S52.1 Fracture of upper end of radius
0.710 0.289 0.000
I21 Acute myocardial infarction
0.710 0.290 0.000
E83 Disorders of mineral metabolism
0.710 0.290 0.000
I47.0 Reentry ventricular arrhythmia
0.710 0.290 0.000
M13 Other arthritis
0.710 0.290 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.709 0.291 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.708 0.292 0.000
S51.0 Open wound of elbow
0.707 0.292 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.707 0.293 0.000
J41 Simple and mucopurulent chronic bronchitis
0.707 0.293 0.000
S40-S49 Injuries to the shoulder and upper arm
0.705 0.295 0.000
R01 Cardiac murmurs and other cardiac sounds
0.704 0.296 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.703 0.297 0.000
S52.5 Fracture of lower end of radius
0.703 0.297 0.000
M14 Arthropathies in other diseases classified elsewhere
0.701 0.299 0.000
M12 Other specific arthropathies
0.701 0.299 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.701 0.299 0.000
M08 Juvenile arthritis
0.701 0.299 0.000
M91-M94 Chondropathies
0.701 0.299 0.000
R34 Anuria and oliguria
0.699 0.301 0.000
M06.8 Other specified rheumatoid arthritis
0.699 0.301 0.000
M06.3 Rheumatoid nodule
0.699 0.301 0.000
M06.2 Rheumatoid bursitis
0.699 0.301 0.000
M06.1 Adult-onset Still's disease
0.699 0.301 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.698 0.302 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.698 0.302 0.000
Q35-Q37 Cleft lip and cleft palate
0.698 0.302 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.698 0.302 0.000
Q60-Q64 Congenital malformations of the urinary system
0.698 0.302 0.000
I05 Rheumatic mitral valve diseases
0.698 0.302 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.697 0.302 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.696 0.304 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.696 0.304 0.000
Q00-Q07 Congenital malformations of the nervous system
0.694 0.306 0.000
E22 Hyperfunction of pituitary gland
0.693 0.307 0.000
T86 Failure and rejection of transplanted organs and tissues
0.693 0.307 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.692 0.308 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.692 0.308 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.692 0.308 0.000
T91 Sequelae of injuries of neck and trunk
0.691 0.309 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.691 0.309 0.000
S79.9 Unspecified injury of hip and thigh
0.690 0.309 0.000
M00-M03 Infectious arthropathies
0.688 0.311 0.000
T92 Sequelae of injuries of upper limb
0.688 0.312 0.000
U51 Admission status on psychiatric patients
0.688 0.312 0.000
Chapter VI Diseases of the nervous system
0.687 0.313 0.000
Q28 Other congenital malformations of circulatory system
0.687 0.313 0.000
S78 Traumatic amputation of hip and thigh
0.687 0.313 0.000
S77 Crushing injury of hip and thigh
0.687 0.313 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.687 0.313 0.000
S75 Injury of blood vessels at hip and thigh level
0.687 0.313 0.000
S74 Injury of nerves at hip and thigh level
0.687 0.313 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.687 0.313 0.000
I42.0 Dilated cardiomyopathy
0.687 0.313 0.000
R02 Gangrene, not elsewhere classified
0.686 0.313 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.686 0.314 0.000
M80 Osteoporosis with pathological fracture
0.685 0.315 0.000
M81 Osteoporosis without pathological fracture
0.685 0.315 0.000
J90 Pleural effusion, not elsewhere classified
0.685 0.315 0.000
S10-S19 Injuries to the neck
0.684 0.316 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.684 0.316 0.000
M85.8 Other specified disorders of bone density and structure
0.683 0.317 0.000
T87 Complications peculiar to reattachment and amputation
0.681 0.319 0.000
I20.1 Angina pectoris with documented spasm
0.680 0.320 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.678 0.322 0.000
T66-T78 Other and unspecified effects of external causes
0.677 0.323 0.000
R36 Urethral discharge
0.674 0.326 0.000
E87.0 Hyperosmolality and hypernatraemia
0.674 0.326 0.000
I35.8 Other aortic valve disorders
0.673 0.327 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.673 0.327 0.000
I42.5 Other restrictive cardiomyopathy
0.673 0.327 0.000
I42.4 Endocardial fibroelastosis
0.673 0.327 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.673 0.327 0.000
S70.0 Contusion of hip
0.673 0.327 0.000
S70.1 Contusion of thigh
0.672 0.328 0.000
M49 Spondylopathies in diseases classified elsewhere
0.671 0.329 0.000
T18 Foreign body in alimentary tract
0.671 0.329 0.000
J43.8 Other emphysema
0.670 0.330 0.000
J43.1 Panlobular emphysema
0.670 0.330 0.000
J43.0 MacLeod's syndrome
0.670 0.330 0.000
S59 Other and unspecified injuries of forearm
0.668 0.332 0.000
S58 Traumatic amputation of forearm
0.668 0.332 0.000
S57 Crushing injury of forearm
0.668 0.332 0.000
S56 Injury of muscle and tendon at forearm level
0.668 0.332 0.000
S55 Injury of blood vessels at forearm level
0.668 0.332 0.000
S54 Injury of nerves at forearm level
0.668 0.332 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.668 0.332 0.000
E87.5 Hyperkalaemia
0.668 0.332 0.000
I07.1 Tricuspid insufficiency
0.667 0.333 0.000
S00-S09 Injuries to the head
0.666 0.334 0.000
T79-T79 Certain early complications of trauma
0.666 0.334 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.665 0.335 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.664 0.336 0.000
Q26 Congenital malformations of great veins
0.664 0.336 0.000
Q25 Congenital malformations of great arteries
0.664 0.336 0.000
Q24 Other congenital malformations of heart
0.664 0.336 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.664 0.336 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.664 0.336 0.000
R47.8 Other and unspecified speech disturbances
0.663 0.337 0.000
I47.2 Ventricular tachycardia
0.662 0.338 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.660 0.340 0.000
E10-E14 Diabetes mellitus
0.660 0.340 0.000
M47 Spondylosis
0.659 0.341 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.659 0.341 0.000
S51.9 Open wound of forearm, part unspecified
0.658 0.341 0.000
J21 Acute bronchiolitis
0.657 0.343 0.000
J20 Acute bronchitis
0.657 0.343 0.000
J18 Pneumonia, organism unspecified
0.657 0.343 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.656 0.344 0.000
S32.5 Fracture of pubis
0.655 0.345 0.000
I30 Acute pericarditis
0.655 0.345 0.000
S52.7 Multiple fractures of forearm
0.654 0.346 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.654 0.346 0.000
I28 Other diseases of pulmonary vessels
0.653 0.346 0.000
H43-H45 Disorders of vitreous body and globe
0.650 0.350 0.000
T93 Sequelae of injuries of lower limb
0.649 0.351 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.649 0.351 0.000
I42.2 Other hypertrophic cardiomyopathy
0.649 0.351 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.648 0.352 0.000
I46 Cardiac arrest
0.647 0.352 0.000
M83 Adult osteomalacia
0.647 0.353 0.000
M82 Osteoporosis in diseases classified elsewhere
0.647 0.353 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.647 0.353 0.000
E04 Other non-toxic goitre
0.647 0.353 0.000
J96 Respiratory failure, not elsewhere classified
0.646 0.354 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.646 0.354 0.000
S32.3 Fracture of ilium
0.646 0.354 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.646 0.354 0.000
M11 Other crystal arthropathies
0.646 0.354 0.000
S72.4 Fracture of lower end of femur
0.644 0.356 0.000
Q51 Congenital malformations of uterus and cervix
0.644 0.356 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.644 0.356 0.000
J93 Pneumothorax
0.644 0.356 0.000
E23 Hypofunction and other disorders of pituitary gland
0.643 0.357 0.000
U80.0 Penicillin resistant agent
0.643 0.357 0.000
I44.5 Left posterior fascicular block
0.642 0.357 0.000
I44.4 Left anterior fascicular block
0.642 0.357 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.642 0.358 0.000
V40-V49 Car occupant injured in transport accident
0.642 0.358 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.639 0.361 0.000
S50 Superficial injury of forearm
0.638 0.362 0.000
I44.6 Other and unspecified fascicular block
0.637 0.363 0.000
H04 Disorders of lachrymal system
0.637 0.363 0.000
J94 Other pleural conditions
0.637 0.363 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.633 0.367 0.000
I08 Multiple valve diseases
0.632 0.368 0.000
Y52 Agents primarily affecting the cardiovascular system
0.632 0.368 0.000
M85.6 Other cyst of bone
0.632 0.368 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.631 0.369 0.000
M46 Other inflammatory spondylopathies
0.631 0.369 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.631 0.369 0.000
R26 Abnormalities of gait and mobility
0.630 0.370 0.000
I24.1 Dressler's syndrome
0.630 0.370 0.000
I21.9 Acute myocardial infarction, unspecified
0.629 0.371 0.000
I09 Other rheumatic heart diseases
0.629 0.371 0.000
I06 Rheumatic aortic valve diseases
0.629 0.371 0.000
S32.4 Fracture of acetabulum
0.629 0.371 0.000
R07.1 Chest pain on breathing
0.628 0.372 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.628 0.372 0.000
S37 Injury of urinary and pelvic organs
0.628 0.372 0.000
S36 Injury of intra-abdominal organs
0.628 0.372 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.628 0.372 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.628 0.372 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.628 0.372 0.000
S31 Open wound of abdomen, lower back and pelvis
0.628 0.372 0.000
R06.8 Other and unspecified abnormalities of breathing
0.628 0.372 0.000
T90 Sequelae of injuries of head
0.627 0.373 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.627 0.373 0.000
U50 Level of care administered to neonates
0.627 0.373 0.000
U07 Emergency use of U07
0.627 0.373 0.000
U06 Emergency use of U06
0.627 0.373 0.000
U04 Severe acute respiratory syndrome [SARS]
0.627 0.373 0.000
U52 First in a series of a regular day/night admissions
0.627 0.373 0.000
I33.0 Acute and subacute infective endocarditis
0.626 0.374 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.626 0.374 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.625 0.375 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.625 0.375 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.624 0.375 0.000
E53 Deficiency of other B group vitamins
0.624 0.376 0.000
J98.9 Respiratory disorder, unspecified
0.623 0.377 0.000
S52.10 Fracture of upper end of radius (closed)
0.622 0.378 0.000
T98 Sequelae of other and unspecified effects of external causes
0.621 0.379 0.000
T95 Sequelae of burns, corrosions and frostbite
0.621 0.379 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.621 0.379 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.621 0.379 0.000
I44.3 Other and unspecified atrioventricular block
0.621 0.379 0.000
S70.8 Other superficial injuries of hip and thigh
0.620 0.380 0.000
S70.7 Multiple superficial injuries of hip and thigh
0.620 0.380 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.620 0.380 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.618 0.382 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.616 0.384 0.000
H10-H13 Disorders of conjunctiva
0.616 0.384 0.000
E87.3 Alkalosis
0.616 0.384 0.000
S52.8 Fracture of other parts of forearm
0.615 0.385 0.000
E85 Amyloidosis
0.614 0.386 0.000
E84 Cystic fibrosis
0.614 0.386 0.000
E79 Disorders of purine and pyrimidine metabolism
0.614 0.386 0.000
E77 Disorders of glycoprotein metabolism
0.614 0.386 0.000
E76 Disorders of glycosaminoglycan metabolism
0.614 0.386 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.614 0.386 0.000
E74 Other disorders of carbohydrate metabolism
0.614 0.386 0.000
E73 Lactose intolerance
0.614 0.386 0.000
E72 Other disorders of amino-acid metabolism
0.614 0.386 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.614 0.386 0.000
E70 Disorders of aromatic amino-acid metabolism
0.614 0.386 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.614 0.386 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.614 0.386 0.000
W50-W64 Exposure to animate mechanical forces
0.613 0.387 0.000
I35.0 Aortic (valve) stenosis
0.613 0.387 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.612 0.388 0.000
R47.0 Dysphasia and aphasia
0.612 0.388 0.000
I49.2 Junctional premature depolarisation
0.611 0.389 0.000
I49.1 Atrial premature depolarisation
0.611 0.389 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.610 0.390 0.000
S72.3 Fracture of shaft of femur
0.610 0.390 0.000
S40 Superficial injury of shoulder and upper arm
0.610 0.390 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.609 0.391 0.000
M10 Gout
0.609 0.391 0.000
I45.6 Preexcitation syndrome
0.609 0.391 0.000
S52.50 Fracture of lower end of radius (closed)
0.609 0.391 0.000
S72.2 Subtrochanteric fracture
0.606 0.394 0.000
M67 Other disorders of synovium and tendon
0.606 0.394 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.606 0.394 0.000
E87.4 Mixed disorder of acid-base balance
0.606 0.394 0.000
M07.3 Other psoriatic arthropathies
0.605 0.395 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.605 0.395 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.604 0.396 0.000
J18.1 Lobar pneumonia, unspecified
0.603 0.397 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.603 0.397 0.000
I35.9 Aortic valve disorder, unspecified
0.601 0.399 0.000
M87 Osteonecrosis
0.600 0.400 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.600 0.400 0.000
J69 Pneumonitis due to solids and liquids
0.599 0.400 0.000
Q85 Phakomatoses, not elsewhere classified
0.599 0.401 0.000
S52.9 Fracture of forearm, part unspecified
0.598 0.402 0.000
S52.4 Fracture of shafts of both ulna and radius
0.598 0.402 0.000
S52.3 Fracture of shaft of radius
0.598 0.402 0.000
S52.2 Fracture of shaft of ulna
0.598 0.402 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.597 0.403 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.597 0.403 0.000
E04.9 Non-toxic goitre, unspecified
0.597 0.403 0.000
I35.1 Aortic (valve) insufficiency
0.596 0.404 0.000
V20-V29 Motorcycle rider injured in transport accident
0.595 0.405 0.000
T23 Burn and corrosion of wrist and hand
0.595 0.405 0.000
S90 Superficial injury of ankle and foot
0.595 0.405 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.595 0.405 0.000
I45.9 Conduction disorder, unspecified
0.594 0.406 0.000
M13.0 Polyarthritis, unspecified
0.594 0.406 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.593 0.407 0.000
Q27.3 Peripheral arteriovenous malformation
0.593 0.407 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.592 0.408 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.592 0.408 0.000
S92 Fracture of foot, except ankle
0.592 0.408 0.000
I51.9 Heart disease, unspecified
0.591 0.409 0.000
H55-H59 Other disorders of eye and adnexa
0.591 0.409 0.000
G30-G32 Other degenerative diseases of the nervous system
0.591 0.409 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.590 0.410 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.589 0.411 0.000
I27.9 Pulmonary heart disease, unspecified
0.589 0.411 0.000
I27.8 Other specified pulmonary heart diseases
0.589 0.411 0.000
I27.1 Kyphoscoliotic heart disease
0.589 0.411 0.000
S51.8 Open wound of other parts of forearm
0.589 0.411 0.000
S51.7 Multiple open wounds of forearm
0.589 0.411 0.000
S81 Open wound of lower leg
0.588 0.412 0.000
I45.2 Bifascicular block
0.588 0.412 0.000
Q43 Other congenital malformations of intestine
0.587 0.413 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.587 0.413 0.000
J98.8 Other specified respiratory disorders
0.587 0.413 0.000
J98.6 Disorders of diaphragm
0.587 0.413 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.587 0.413 0.000
J98.3 Compensatory emphysema
0.587 0.413 0.000
J98.2 Interstitial emphysema
0.587 0.413 0.000
S71.1 Open wound of thigh
0.585 0.415 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.585 0.415 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.584 0.416 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.584 0.416 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.584 0.416 0.000
E10 Insulin-dependent diabetes mellitus
0.584 0.416 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.583 0.417 0.000
E34 Other endocrine disorders
0.583 0.417 0.000
E32 Diseases of thymus
0.583 0.417 0.000
E31 Polyglandular dysfunction
0.583 0.417 0.000
E30 Disorders of puberty, not elsewhere classified
0.583 0.417 0.000
E26 Hyperaldosteronism
0.583 0.417 0.000
E25 Adrenogenital disorders
0.583 0.417 0.000
E24 Cushing's syndrome
0.583 0.417 0.000
E20 Hypoparathyroidism
0.583 0.417 0.000
E46 Unspecified protein-energy malnutrition
0.583 0.417 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.582 0.418 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.582 0.418 0.000
Q23.4 Hypoplastic left heart syndrome
0.582 0.418 0.000
Q23.3 Congenital mitral insufficiency
0.582 0.418 0.000
Q23.2 Congenital mitral stenosis
0.582 0.418 0.000
Q23.0 Congenital stenosis of aortic valve
0.582 0.418 0.000
R30.1 Vesical tenesmus
0.582 0.418 0.000
I45.1 Other and unspecified right bundle-branch block
0.581 0.419 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.580 0.419 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.580 0.420 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.580 0.420 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.580 0.420 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.580 0.420 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.580 0.420 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.580 0.420 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.580 0.420 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.580 0.420 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.580 0.420 0.000
E87.7 Fluid overload
0.580 0.420 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.579 0.421 0.000
Q21.8 Other congenital malformations of cardiac septa
0.579 0.421 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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