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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80282661
log Bayes Factor = 0.017531
Chromosome 17   position 13,252,073  (GRCh37) Explore rs80282661 on Ensembl!
Variant rs80282661 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
H30-H36 Disorders of choroid and retina
0.061 0.939 0.000
Chapter VII Diseases of the eye and adnexa
0.061 0.939 0.000
H35 Other retinal disorders
0.059 0.941 0.000
H25-H28 Disorders of lens
0.056 0.944 0.000
H40-H42 Glaucoma
0.055 0.945 0.000
H35.8 Other specified retinal disorders
0.053 0.947 0.000
H33 Retinal detachments and breaks
0.052 0.948 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.051 0.949 0.000
H43-H45 Disorders of vitreous body and globe
0.051 0.949 0.000
H40 Glaucoma
0.051 0.949 0.000
H25 Senile cataract
0.050 0.950 0.000
H35.0 Background retinopathy and retinal vascular changes
0.049 0.951 0.000
H36 Retinal disorders in diseases classified elsewhere
0.048 0.951 0.000
H53-H54 Visual disturbances and blindness
0.048 0.952 0.000
H55-H59 Other disorders of eye and adnexa
0.047 0.953 0.000
H33.3 Retinal breaks without detachment
0.047 0.953 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.047 0.953 0.000
H26 Other cataract
0.046 0.954 0.000
H40.0 Glaucoma suspect
0.046 0.954 0.000
H10-H13 Disorders of conjunctiva
0.046 0.954 0.000
H34 Retinal vascular occlusions
0.045 0.955 0.000
H35.4 Peripheral retinal degeneration
0.045 0.955 0.000
H25.0 Senile incipient cataract
0.044 0.956 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.044 0.956 0.000
H31 Other disorders of choroid
0.044 0.956 0.000
H30 Chorioretinal inflammation
0.044 0.956 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.044 0.956 0.000
H40.2 Primary angle-closure glaucoma
0.044 0.956 0.000
H43 Disorders of vitreous body
0.044 0.956 0.000
H35.3 Degeneration of macula and posterior pole
0.043 0.957 0.000
H35.9 Retinal disorder, unspecified
0.042 0.958 0.000
H35.7 Separation of retinal layers
0.042 0.958 0.000
H35.6 Retinal haemorrhage
0.042 0.958 0.000
H35.5 Hereditary retinal dystrophy
0.042 0.958 0.000
H35.2 Other proliferative retinopathy
0.042 0.958 0.000
H35.1 Retinopathy of prematurity
0.042 0.958 0.000
H04 Disorders of lachrymal system
0.042 0.958 0.000
H40.1 Primary open-angle glaucoma
0.042 0.958 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.041 0.959 0.000
H25.8 Other senile cataract
0.041 0.959 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.040 0.959 0.000
H27 Other disorders of lens
0.040 0.959 0.000
H02 Other disorders of eyelid
0.040 0.960 0.000
H25.1 Senile nuclear cataract
0.040 0.960 0.000
H42 Glaucoma in diseases classified elsewhere
0.040 0.960 0.000
H54 Blindness and low vision
0.040 0.960 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.040 0.960 0.000
H36.0 Diabetic retinopathy
0.039 0.961 0.000
H26.4 After-cataract
0.038 0.962 0.000
H33.5 Other retinal detachments
0.038 0.962 0.000
H33.4 Traction detachment of retina
0.038 0.962 0.000
H33.1 Retinoschisis and retinal cysts
0.038 0.962 0.000
H43.1 Vitreous haemorrhage
0.037 0.963 0.000
H44 Disorders of globe
0.037 0.963 0.000
H05 Disorders of orbit
0.037 0.963 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.037 0.963 0.000
H33.0 Retinal detachment with retinal break
0.037 0.963 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.037 0.963 0.000
H40.8 Other glaucoma
0.037 0.963 0.000
H40.6 Glaucoma secondary to drugs
0.037 0.963 0.000
H40.5 Glaucoma secondary to other eye disorders
0.037 0.963 0.000
H40.4 Glaucoma secondary to eye inflammation
0.037 0.963 0.000
H40.3 Glaucoma secondary to eye trauma
0.037 0.963 0.000
H20 Iridocyclitis
0.036 0.963 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.036 0.964 0.000
H25.2 Senile cataract, morgagnian type
0.036 0.964 0.000
H33.2 Serous retinal detachment
0.036 0.964 0.000
H04.1 Other disorders of lachrymal gland
0.036 0.964 0.000
H55 Nystagmus and other irregular eye movements
0.035 0.965 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.035 0.965 0.000
H43.3 Other vitreous opacities
0.035 0.965 0.000
H01 Other inflammation of eyelid
0.035 0.965 0.000
H11 Other disorders of conjunctiva
0.035 0.965 0.000
H26.8 Other specified cataract
0.035 0.965 0.000
H06.2 Dysthyroid exophthalmos
0.034 0.966 0.000
H26.9 Cataract, unspecified
0.034 0.966 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.034 0.966 0.000
H57 Other disorders of eye and adnexa
0.034 0.966 0.000
H53 Visual disturbances
0.034 0.966 0.000
H34.8 Other retinal vascular occlusions
0.034 0.966 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.034 0.966 0.000
H21 Other disorders of iris and ciliary body
0.034 0.966 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.034 0.966 0.000
H18 Other disorders of cornea
0.034 0.966 0.000
H17 Corneal scars and opacities
0.034 0.966 0.000
H16 Keratitis
0.034 0.966 0.000
H15 Disorders of sclera
0.034 0.966 0.000
H54.7 Unspecified visual loss
0.034 0.966 0.000
H26.3 Drug-induced cataract
0.033 0.966 0.000
H26.2 Complicated cataract
0.033 0.966 0.000
H26.1 Traumatic cataract
0.033 0.966 0.000
H26.0 Infantile, juvenile and presenile cataract
0.033 0.966 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.033 0.967 0.000
H10 Conjunctivitis
0.033 0.967 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.033 0.967 0.000
H02.0 Entropion and trichiasis of eyelid
0.033 0.967 0.000
H34.9 Retinal vascular occlusion, unspecified
0.033 0.967 0.000
H34.2 Other retinal artery occlusions
0.033 0.967 0.000
H34.1 Central retinal artery occlusion
0.033 0.967 0.000
H34.0 Transient retinal artery occlusion
0.033 0.967 0.000
H00 Hordeolum and chalazion
0.033 0.967 0.000
H02.1 Ectropion of eyelid
0.032 0.967 0.000
H30.9 Chorioretinal inflammation, unspecified
0.032 0.968 0.000
H30.8 Other chorioretinal inflammations
0.032 0.968 0.000
H30.2 Posterior cyclitis
0.032 0.968 0.000
H30.1 Disseminated chorioretinal inflammation
0.032 0.968 0.000
H30.0 Focal chorioretinal inflammation
0.032 0.968 0.000
H31.9 Disorder of choroid, unspecified
0.032 0.968 0.000
H31.8 Other specified disorders of choroid
0.032 0.968 0.000
H31.4 Choroidal detachment
0.032 0.968 0.000
H31.3 Choroidal haemorrhage and rupture
0.032 0.968 0.000
H31.2 Hereditary choroidal dystrophy
0.032 0.968 0.000
H31.1 Choroidal degeneration
0.032 0.968 0.000
H31.0 Chorioretinal scars
0.032 0.968 0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.032 0.968 0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.032 0.968 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.032 0.968 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.032 0.968 0.000
H46 Optic neuritis
0.032 0.968 0.000
H02.9 Disorder of eyelid, unspecified
0.032 0.968 0.000
H43.9 Disorder of vitreous body, unspecified
0.032 0.968 0.000
H43.2 Crystalline deposits in vitreous body
0.032 0.968 0.000
H43.0 Vitreous prolapse
0.032 0.968 0.000
H02.5 Other disorders affecting eyelid function
0.031 0.969 0.000
H25.9 Senile cataract, unspecified
0.031 0.969 0.000
H02.4 Ptosis of eyelid
0.031 0.969 0.000
H43.8 Other disorders of vitreous body
0.030 0.969 0.000
H04.9 Disorder of lachrymal system, unspecified
0.030 0.969 0.000
H04.8 Other disorders of lachrymal system
0.030 0.969 0.000
H04.6 Other changes in lachrymal passages
0.030 0.969 0.000
H04.4 Chronic inflammation of lachrymal passages
0.030 0.969 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.030 0.969 0.000
H04.0 Dacryoadenitis
0.030 0.969 0.000
H06.3 Other disorders of orbit in diseases classified elsewhere
0.030 0.970 0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.030 0.970 0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.030 0.970 0.000
H27.9 Disorder of lens, unspecified
0.029 0.971 0.000
H27.8 Other specified disorders of lens
0.029 0.971 0.000
H27.1 Dislocation of lens
0.029 0.971 0.000
H27.0 Aphakia
0.029 0.971 0.000
H28.8 Other disorders of lens in diseases classified elsewhere
0.029 0.971 0.000
H28.2 Cataract in other diseases classified elsewhere
0.029 0.971 0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases
0.029 0.971 0.000
H28.0 Diabetic cataract
0.029 0.971 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.029 0.971 0.000
H02.6 Xanthelasma of eyelid
0.029 0.971 0.000
H02.2 Lagophthalmos
0.029 0.971 0.000
H20.9 Iridocyclitis, unspecified
0.029 0.971 0.000
H54.4 Blindness, one eye
0.029 0.971 0.000
H42.8 Glaucoma in other diseases classified elsewhere
0.029 0.971 0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases
0.029 0.971 0.000
H54.9 Unspecified visual impairment (binocular)
0.029 0.971 0.000
H54.6 Unqualified visual loss, one eye
0.029 0.971 0.000
H54.5 Low vision, one eye
0.029 0.971 0.000
H54.3 Unqualified visual loss, both eyes
0.029 0.971 0.000
H54.2 Low vision, both eyes
0.029 0.971 0.000
H54.1 Blindness, one eye, low vision, other eye
0.029 0.971 0.000
H54.0 Blindness, both eyes
0.029 0.971 0.000
H51 Other disorders of binocular movement
0.029 0.971 0.000
H49 Paralytic strabismus
0.029 0.971 0.000
H59.8 Other postprocedural disorders of eye and adnexa
0.028 0.971 0.000
H53.1 Subjective visual disturbances
0.028 0.972 0.000
H53.0 Amblyopia ex anopsia
0.028 0.972 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.027 0.973 0.000
H04.2 Epiphora
0.027 0.973 0.000
H44.2 Degenerative myopia
0.027 0.973 0.000
H50 Other strabismus
0.027 0.973 0.000
H44.9 Disorder of globe, unspecified
0.027 0.973 0.000
H44.8 Other disorders of globe
0.027 0.973 0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic
0.027 0.973 0.000
H44.6 Retained (old) intraocular foreign body, magnetic
0.027 0.973 0.000
H44.5 Degenerated conditions of globe
0.027 0.973 0.000
H44.4 Hypotony of eye
0.027 0.973 0.000
H44.3 Other degenerative disorders of globe
0.027 0.973 0.000
H44.1 Other endophthalmitis
0.027 0.973 0.000
H44.0 Purulent endophthalmitis
0.027 0.973 0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere
0.027 0.973 0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere
0.027 0.973 0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere
0.027 0.973 0.000
H05.9 Disorder of orbit, unspecified
0.027 0.973 0.000
H05.8 Other disorders of orbit
0.027 0.973 0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.027 0.973 0.000
H05.4 Enophthalmos
0.027 0.973 0.000
H05.3 Deformity of orbit
0.027 0.973 0.000
H05.2 Exophthalmic conditions
0.027 0.973 0.000
H05.1 Chronic inflammatory disorders of orbit
0.027 0.973 0.000
H05.0 Acute inflammation of orbit
0.027 0.973 0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere
0.026 0.973 0.000
H45.1 Endophthalmitis in diseases classified elsewhere
0.026 0.973 0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere
0.026 0.973 0.000
H52 Disorders of refraction and accommodation
0.026 0.973 0.000
H20.8 Other iridocyclitis
0.026 0.974 0.000
H20.2 Lens-induced iridocyclitis
0.026 0.974 0.000
H20.1 Chronic iridocyclitis
0.026 0.974 0.000
H20.0 Acute and subacute iridocyclitis
0.026 0.974 0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified
0.026 0.974 0.000
H59.0 Vitreous syndrome following cataract surgery
0.026 0.974 0.000
H01.9 Inflammation of eyelid, unspecified
0.025 0.975 0.000
H01.8 Other specified inflammation of eyelid
0.025 0.975 0.000
H01.1 Non-infectious dermatoses of eyelid
0.025 0.975 0.000
H11.9 Disorder of conjunctiva, unspecified
0.025 0.975 0.000
H11.8 Other specified disorders of conjunctiva
0.025 0.975 0.000
H11.3 Conjunctival haemorrhage
0.025 0.975 0.000
H11.2 Conjunctival scars
0.025 0.975 0.000
H11.1 Conjunctival degenerations and deposits
0.025 0.975 0.000
H11.0 Pterygium
0.025 0.975 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.025 0.975 0.000
H57.8 Other specified disorders of eye and adnexa
0.025 0.975 0.000
H57.1 Ocular pain
0.025 0.975 0.000
H57.0 Anomalies of pupillary function
0.025 0.975 0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere
0.025 0.975 0.000
H58.8 Visual disturbances in diseases classified elsewhere
0.025 0.975 0.000
H58.1 Visual disturbances in diseases classified elsewhere
0.025 0.975 0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere
0.025 0.975 0.000
H53.9 Visual disturbance, unspecified
0.025 0.975 0.000
H53.6 Night blindness
0.025 0.975 0.000
H53.5 Colour vision deficiencies
0.025 0.975 0.000
H53.3 Other disorders of binocular vision
0.025 0.975 0.000
H15.9 Disorder of sclera, unspecified
0.024 0.975 0.000
H15.8 Other disorders of sclera
0.024 0.975 0.000
H15.1 Episcleritis
0.024 0.975 0.000
H15.0 Scleritis
0.024 0.975 0.000
H16.9 Keratitis, unspecified
0.024 0.975 0.000
H16.8 Other keratitis
0.024 0.975 0.000
H16.4 Corneal neovascularisation
0.024 0.975 0.000
H16.3 Interstitial and deep keratitis
0.024 0.975 0.000
H16.2 Keratoconjunctivitis
0.024 0.975 0.000
H16.1 Other superficial keratitis without conjunctivitis
0.024 0.975 0.000
H16.0 Corneal ulcer
0.024 0.975 0.000
H17.9 Corneal scar and opacity, unspecified
0.024 0.975 0.000
H17.8 Other corneal scars and opacities
0.024 0.975 0.000
H17.1 Other central corneal opacity
0.024 0.975 0.000
H17.0 Adherent leukoma
0.024 0.975 0.000
H18.9 Disorder of cornea, unspecified
0.024 0.975 0.000
H18.8 Other specified disorders of cornea
0.024 0.975 0.000
H18.7 Other corneal deformities
0.024 0.975 0.000
H18.6 Keratoconus
0.024 0.975 0.000
H18.5 Hereditary corneal dystrophies
0.024 0.975 0.000
H18.4 Corneal degeneration
0.024 0.975 0.000
H18.3 Changes in corneal membranes
0.024 0.975 0.000
H18.2 Other corneal oedema
0.024 0.975 0.000
H18.1 Bullous keratopathy
0.024 0.975 0.000
H18.0 Corneal pigmentations and deposits
0.024 0.975 0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere
0.024 0.975 0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.024 0.975 0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
0.024 0.975 0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis
0.024 0.975 0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere
0.024 0.975 0.000
H21.9 Disorder of iris and ciliary body, unspecified
0.024 0.975 0.000
H21.8 Other specified disorders of iris and ciliary body
0.024 0.975 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.024 0.975 0.000
H21.4 Pupillary membranes
0.024 0.975 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.024 0.975 0.000
H21.2 Degeneration of iris and ciliary body
0.024 0.975 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.024 0.975 0.000
H21.0 Hyphaema
0.024 0.975 0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere
0.024 0.975 0.000
H22.1 Iridocyclitis in other diseases classified elsewhere
0.024 0.975 0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere
0.024 0.975 0.000
H10.9 Conjunctivitis, unspecified
0.024 0.976 0.000
H10.8 Other conjunctivitis
0.024 0.976 0.000
H10.5 Blepharoconjunctivitis
0.024 0.976 0.000
H10.4 Chronic conjunctivitis
0.024 0.976 0.000
H10.3 Acute conjunctivitis, unspecified
0.024 0.976 0.000
H10.2 Other acute conjunctivitis
0.024 0.976 0.000
H10.1 Acute atopic conjunctivitis
0.024 0.976 0.000
H10.0 Mucopurulent conjunctivitis
0.024 0.976 0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere
0.024 0.976 0.000
H13.3 Ocular pemphigoid
0.024 0.976 0.000
H13.2 Conjunctivitis in other diseases classified elsewhere
0.024 0.976 0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere
0.024 0.976 0.000
H13.0 Filarial infection of conjunctiva
0.024 0.976 0.000
H53.4 Visual field defects
0.024 0.976 0.000
H02.3 Blepharochalasis
0.024 0.976 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.023 0.976 0.000
H01.0 Blepharitis
0.023 0.977 0.000
H47.7 Disorder of visual pathways, unspecified
0.023 0.977 0.000
H47.6 Disorders of visual cortex
0.023 0.977 0.000
H47.5 Disorders of other visual pathways
0.023 0.977 0.000
H47.4 Disorders of optic chiasm
0.023 0.977 0.000
H47.3 Other disorders of optic disk
0.023 0.977 0.000
H47.2 Optic atrophy
0.023 0.977 0.000
H47.1 Papilloedema, unspecified
0.023 0.977 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.023 0.977 0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere
0.023 0.977 0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere
0.023 0.977 0.000
H48.0 Optic atrophy in diseases classified elsewhere
0.023 0.977 0.000
H40.9 Glaucoma, unspecified
0.022 0.978 0.000
H49.9 Paralytic strabismus, unspecified
0.021 0.979 0.000
H49.8 Other paralytic strabismus
0.021 0.979 0.000
H49.4 Progressive external ophthalmoplegia
0.021 0.979 0.000
H49.3 Total (external) ophthalmoplegia
0.021 0.979 0.000
H49.2 Sixth [abducent] nerve palsy
0.021 0.979 0.000
H49.1 Fourth [trochlear] nerve palsy
0.021 0.979 0.000
H49.0 Third [oculomotor] nerve palsy
0.021 0.979 0.000
H51.9 Disorder of binocular movement, unspecified
0.021 0.979 0.000
H51.8 Other specified disorders of binocular movement
0.021 0.979 0.000
H51.2 Internuclear ophthalmoplegia
0.021 0.979 0.000
H51.1 Convergence insufficiency and excess
0.021 0.979 0.000
H51.0 Palsy of conjugate gaze
0.021 0.979 0.000
H52.0 Hypermetropia
0.020 0.980 0.000
H53.8 Other visual disturbances
0.020 0.980 0.000
H02.8 Other specified disorders of eyelid
0.020 0.980 0.000
H53.2 Diplopia
0.020 0.980 0.000
H50.8 Other specified strabismus
0.019 0.980 0.000
H50.6 Mechanical strabismus
0.019 0.980 0.000
H50.5 Heterophoria
0.019 0.980 0.000
H50.4 Other and unspecified heterotropia
0.019 0.980 0.000
H50.3 Intermittent heterotropia
0.019 0.980 0.000
H50.2 Vertical strabismus
0.019 0.980 0.000
H50.0 Convergent concomitant strabismus
0.019 0.980 0.000
H52.7 Disorder of refraction, unspecified
0.019 0.981 0.000
H52.6 Other disorders of refraction
0.019 0.981 0.000
H52.5 Disorders of accommodation
0.019 0.981 0.000
H52.4 Presbyopia
0.019 0.981 0.000
H52.3 Anisometropia and aniseikonia
0.019 0.981 0.000
H52.2 Astigmatism
0.019 0.981 0.000
H00.1 Chalazion
0.019 0.981 0.000
H50.9 Strabismus, unspecified
0.019 0.981 0.000
H50.1 Divergent concomitant strabismus
0.018 0.982 0.000
H52.1 Myopia
0.016 0.984 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.010 0.990 0.000
M05-M14 Inflammatory polyarthropathies
0.010 0.990 0.000
M45-M49 Spondylopathies
0.009 0.991 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.009 0.991 0.000
E10-E14 Diabetes mellitus
0.009 0.991 0.000
M13 Other arthritis
0.009 0.991 0.000
M20-M25 Other joint disorders
0.009 0.991 0.000
M70-M79 Other soft tissue disorders
0.008 0.992 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.008 0.992 0.000
M25 Other joint disorders, not elsewhere classified
0.008 0.992 0.000
E10 Insulin-dependent diabetes mellitus
0.008 0.992 0.000
M86-M90 Other osteopathies
0.008 0.992 0.000
M48 Other spondylopathies
0.008 0.992 0.000
I30-I52 Other forms of heart disease
0.008 0.992 0.000
M10 Gout
0.008 0.992 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.008 0.992 0.000
M13.9 Arthritis, unspecified
0.008 0.992 0.000
M07 Psoriatic and enteropathic arthropathies
0.008 0.992 0.000
E00-E07 Disorders of thyroid gland
0.008 0.992 0.000
# Top node
0.008 0.992 0.000
E10.9 Without complications
0.008 0.992 0.000
M25.5 Pain in joint
0.008 0.992 0.000
I35 Nonrheumatic aortic valve disorders
0.008 0.992 0.000
M11 Other crystal arthropathies
0.008 0.992 0.000
E14 Unspecified diabetes mellitus
0.008 0.992 0.000
I50 Heart failure
0.008 0.992 0.000
M40-M43 Deforming dorsopathies
0.007 0.992 0.000
M48.0 Spinal stenosis
0.007 0.992 0.000
M80-M85 Disorders of bone density and structure
0.007 0.993 0.000
M91-M94 Chondropathies
0.007 0.993 0.000
M60-M63 Disorders of muscles
0.007 0.993 0.000
M00-M03 Infectious arthropathies
0.007 0.993 0.000
M06 Other rheumatoid arthritis
0.007 0.993 0.000
Chapter IX Diseases of the circulatory system
0.007 0.993 0.000
M47 Spondylosis
0.007 0.993 0.000
M25.57 Pain in joint (Ankle and foot)
0.007 0.993 0.000
M14 Arthropathies in other diseases classified elsewhere
0.007 0.993 0.000
M12 Other specific arthropathies
0.007 0.993 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.007 0.993 0.000
M08 Juvenile arthritis
0.007 0.993 0.000
M05 Seropositive rheumatoid arthritis
0.007 0.993 0.000
E20-E35 Disorders of other endocrine glands
0.007 0.993 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.007 0.993 0.000
M24 Other specific joint derangements
0.007 0.993 0.000
M46 Other inflammatory spondylopathies
0.007 0.993 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.007 0.993 0.000
I71 Aortic aneurysm and dissection
0.007 0.993 0.000
E65-E68 Obesity and other hyperalimentation
0.007 0.993 0.000
M65-M68 Disorders of synovium and tendon
0.007 0.993 0.000
M22 Disorders of patella
0.007 0.993 0.000
I77 Other disorders of arteries and arterioles
0.007 0.993 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.007 0.993 0.000
I44 Atrioventricular and left bundle-branch block
0.007 0.993 0.000
E50-E64 Other nutritional deficiencies
0.007 0.993 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.007 0.993 0.000
M25.7 Osteophyte
0.007 0.993 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.007 0.993 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.007 0.993 0.000
M25.58 Pain in joint (Other)
0.007 0.993 0.000
M21 Other acquired deformities of limbs
0.007 0.993 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.007 0.993 0.000
M49 Spondylopathies in diseases classified elsewhere
0.007 0.993 0.000
M45 Ankylosing spondylitis
0.007 0.993 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.007 0.993 0.000
M10.9 Gout, unspecified
0.007 0.993 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.007 0.993 0.000
M13.98 Arthritis, unspecified (Other)
0.007 0.993 0.000
E04 Other non-toxic goitre
0.007 0.993 0.000
I74 Arterial embolism and thrombosis
0.007 0.993 0.000
M77 Other enthesopathies
0.007 0.993 0.000
I50.1 Left ventricular failure
0.007 0.993 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.007 0.993 0.000
M25.56 Pain in joint (Lower leg)
0.007 0.993 0.000
I73 Other peripheral vascular diseases
0.007 0.993 0.000
E40-E46 Malnutrition
0.006 0.993 0.000
M87 Osteonecrosis
0.006 0.993 0.000
M07.3 Other psoriatic arthropathies
0.006 0.993 0.000
I45 Other conduction disorders
0.006 0.993 0.000
I35.9 Aortic valve disorder, unspecified
0.006 0.993 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.006 0.993 0.000
I51 Complications and ill-defined descriptions of heart disease
0.007 0.993 0.000
E10.3 With ophthalmic complications
0.006 0.993 0.000
E13 Other specified diabetes mellitus
0.006 0.993 0.000
E12 Malnutrition-related diabetes mellitus
0.006 0.993 0.000
E14.9 Without complications
0.006 0.993 0.000
M88 Paget's disease of bone [osteitis deformans]
0.006 0.993 0.000
M13.8 Other specified arthritis
0.006 0.994 0.000
M13.1 Monoarthritis, not elsewhere classified
0.006 0.994 0.000
M13.0 Polyarthritis, unspecified
0.006 0.994 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.006 0.994 0.000
M34 Systemic sclerosis
0.006 0.994 0.000
M33 Dermatopolymyositis
0.006 0.994 0.000
M32 Systemic lupus erythematosus
0.006 0.994 0.000
M31 Other necrotising vasculopathies
0.006 0.994 0.000
M30 Polyarteritis nodosa and related conditions
0.006 0.994 0.000
I50.0 Congestive heart failure
0.006 0.994 0.000
E70-E90 Metabolic disorders
0.006 0.994 0.000
M48.06 Spinal stenosis (Lumbar region)
0.006 0.994 0.000
I77.1 Stricture of artery
0.006 0.994 0.000
M76 Enthesopathies of lower limb, excluding foot
0.006 0.994 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.006 0.994 0.000
M71 Other bursopathies
0.006 0.994 0.000
E14.3 With ophthalmic complications
0.006 0.994 0.000
I42 Cardiomyopathy
0.006 0.994 0.000
I70 Atherosclerosis
0.006 0.994 0.000
I51.8 Other ill-defined heart diseases
0.006 0.994 0.000
M99 Biomechanical lesions, not elsewhere classified
0.006 0.994 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.006 0.994 0.000
M48.02 Spinal stenosis (Cervical region)
0.006 0.994 0.000
E11 Non-insulin-dependent diabetes mellitus
0.006 0.994 0.000
T79-T79 Certain early complications of trauma
0.006 0.994 0.000
M11.2 Other chondrocalcinosis
0.006 0.994 0.000
I35.0 Aortic (valve) stenosis
0.006 0.994 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.006 0.994 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.006 0.994 0.000
I44.0 Atrioventricular block, first degree
0.006 0.994 0.000
I73.9 Peripheral vascular disease, unspecified
0.006 0.994 0.000
M25.9 Joint disorder, unspecified
0.006 0.994 0.000
M25.8 Other specified joint disorders
0.006 0.994 0.000
M25.3 Other instability of joint
0.006 0.994 0.000
M25.2 Flail joint
0.006 0.994 0.000
M25.1 Fistula of joint
0.006 0.994 0.000
M25.0 Haemarthrosis
0.006 0.994 0.000
E10.8 With unspecified complications
0.006 0.994 0.000
E10.7 With multiple complications
0.006 0.994 0.000
E10.6 With other specified complications
0.006 0.994 0.000
E10.5 With peripheral circulatory complications
0.006 0.994 0.000
E10.4 With neurological complications
0.006 0.994 0.000
E10.2 With renal complications
0.006 0.994 0.000
E10.1 With ketoacidosis
0.006 0.994 0.000
E10.0 With coma
0.006 0.994 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.006 0.994 0.000
M75 Shoulder lesions
0.006 0.994 0.000
S40-S49 Injuries to the shoulder and upper arm
0.006 0.994 0.000
I31 Other diseases of pericardium
0.006 0.994 0.000
M90 Osteopathies in diseases classified elsewhere
0.006 0.994 0.000
M89 Other disorders of bone
0.006 0.994 0.000
M86 Osteomyelitis
0.006 0.994 0.000
M48.9 Spondylopathy, unspecified
0.006 0.994 0.000
M48.8 Other specified spondylopathies
0.006 0.994 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.006 0.994 0.000
M48.4 Fatigue fracture of vertebra
0.006 0.994 0.000
M48.3 Traumatic spondylopathy
0.006 0.994 0.000
M48.2 Kissing spine
0.006 0.994 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.006 0.994 0.000
M24.1 Other articular cartilage disorders
0.006 0.994 0.000
I46 Cardiac arrest
0.006 0.994 0.000
I52 Other heart disorders in diseases classified elsewhere
0.006 0.994 0.000
I48 Atrial fibrillation and flutter
0.006 0.994 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.006 0.994 0.000
I41 Myocarditis in diseases classified elsewhere
0.006 0.994 0.000
I40 Acute myocarditis
0.006 0.994 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.006 0.994 0.000
I37 Pulmonary valve disorders
0.006 0.994 0.000
I36 Nonrheumatic tricuspid valve disorders
0.006 0.994 0.000
I33 Acute and subacute endocarditis
0.006 0.994 0.000
I32 Pericarditis in diseases classified elsewhere
0.006 0.994 0.000
I30 Acute pericarditis
0.006 0.994 0.000
M72 Fibroblastic disorders
0.006 0.994 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.006 0.994 0.000
M22.8 Other disorders of patella
0.006 0.994 0.000
I78 Diseases of capillaries
0.006 0.994 0.000
M23 Internal derangement of knee
0.006 0.994 0.000
M47.1 Other spondylosis with myelopathy
0.006 0.994 0.000
M70.6 Trochanteric bursitis
0.006 0.994 0.000
M10.4 Other secondary gout
0.006 0.994 0.000
M10.3 Gout due to impairment of renal function
0.006 0.994 0.000
M10.2 Drug-induced gout
0.006 0.994 0.000
M10.1 Lead-induced gout
0.006 0.994 0.000
M10.0 Idiopathic gout
0.006 0.994 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.006 0.994 0.000
I72 Other aneurysm
0.006 0.994 0.000
M10.96 Gout, unspecified (Lower leg)
0.006 0.994 0.000
M80 Osteoporosis with pathological fracture
0.006 0.994 0.000
M13.93 Arthritis, unspecified (Forearm)
0.006 0.994 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.006 0.994 0.000
M43 Other deforming dorsopathies
0.006 0.994 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.006 0.994 0.000
M25.53 Pain in joint (Forearm)
0.006 0.994 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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