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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs8102150
log Bayes Factor = 1.24544
Chromosome 19   position 50,230,327  (GRCh37) Explore rs8102150 on Ensembl!
Variant rs8102150 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.936 0.064 0.000
Chapter IX Diseases of the circulatory system
0.933 0.067 0.000
I60-I69 Cerebrovascular diseases
0.928 0.072 0.000
I63 Cerebral infarction
0.919 0.081 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.918 0.082 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.911 0.089 0.000
M05-M14 Inflammatory polyarthropathies
0.902 0.098 0.000
M06 Other rheumatoid arthritis
0.899 0.101 0.000
M06.9 Rheumatoid arthritis, unspecified
0.896 0.104 0.000
I63.9 Cerebral infarction, unspecified
0.890 0.110 0.000
I67 Other cerebrovascular diseases
0.889 0.111 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.889 0.111 0.000
Chapter V Mental and behavioural disorders
0.877 0.123 0.000
I20-I25 Ischaemic heart diseases
0.873 0.127 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.871 0.129 0.000
I20 Angina pectoris
0.865 0.135 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.853 0.147 0.000
I20.9 Angina pectoris, unspecified
0.851 0.149 0.000
Chapter VI Diseases of the nervous system
0.851 0.149 0.000
Chapter VII Diseases of the eye and adnexa
0.851 0.149 0.000
Chapter I Certain infectious and parasitic diseases
0.846 0.154 0.000
D70 Agranulocytosis
0.845 0.155 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.844 0.156 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.838 0.162 0.000
F41 Other anxiety disorders
0.830 0.170 0.000
H50 Other strabismus
0.828 0.172 0.000
I67.9 Cerebrovascular disease, unspecified
0.827 0.173 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.825 0.175 0.000
M20-M25 Other joint disorders
0.824 0.176 0.000
F41.9 Anxiety disorder, unspecified
0.821 0.179 0.000
I20.8 Other forms of angina pectoris
0.819 0.181 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.811 0.188 0.000
G90-G99 Other disorders of the nervous system
0.797 0.203 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.795 0.205 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.794 0.206 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.793 0.207 0.000
I10-I15 Hypertensive diseases
0.790 0.209 0.000
R50-R69 General symptoms and signs
0.787 0.213 0.000
M20 Acquired deformities of fingers and toes
0.784 0.216 0.000
H50.1 Divergent concomitant strabismus
0.775 0.225 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.773 0.227 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.772 0.228 0.000
D75 Other diseases of blood and blood-forming organs
0.771 0.229 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.752 0.248 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.746 0.254 0.000
R59 Enlarged lymph nodes
0.745 0.255 0.000
G93 Other disorders of brain
0.744 0.256 0.000
I05-I09 Chronic rheumatic heart diseases
0.743 0.257 0.000
R53 Malaise and fatigue
0.742 0.258 0.000
I67.1 Cerebral aneurysm, nonruptured
0.741 0.259 0.000
H53-H54 Visual disturbances and blindness
0.741 0.259 0.000
M20.4 Other hammer toe(s) (acquired)
0.740 0.260 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.738 0.262 0.000
H50.0 Convergent concomitant strabismus
0.737 0.263 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.735 0.265 0.000
H50.9 Strabismus, unspecified
0.735 0.265 0.000
D69 Purpura and other haemorrhagic conditions
0.734 0.266 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.729 0.271 0.000
M86-M90 Other osteopathies
0.725 0.274 0.000
M07 Psoriatic and enteropathic arthropathies
0.718 0.282 0.000
I67.2 Cerebral atherosclerosis
0.716 0.284 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.716 0.284 0.000
Chapter VIII Diseases of the ear and mastoid process
0.712 0.288 0.000
M06.4 Inflammatory polyarthropathy
0.710 0.290 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.709 0.291 0.000
D80-D89 Certain disorders involving the immune mechanism
0.708 0.292 0.000
I12 Hypertensive renal disease
0.706 0.294 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.704 0.296 0.000
Chapter XXII Codes for special purposes
0.700 0.300 0.000
M80-M85 Disorders of bone density and structure
0.697 0.303 0.000
I60 Subarachnoid haemorrhage
0.696 0.304 0.000
I69 Sequelae of cerebrovascular disease
0.695 0.305 0.000
B15-B19 Viral hepatitis
0.690 0.310 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.688 0.312 0.000
B95-B98 Bacterial, viral and other infectious agents
0.687 0.313 0.000
M70-M79 Other soft tissue disorders
0.685 0.315 0.000
H53 Visual disturbances
0.681 0.319 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.680 0.320 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.680 0.320 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.679 0.321 0.000
M24 Other specific joint derangements
0.678 0.322 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.677 0.322 0.000
R51 Headache
0.674 0.326 0.000
M91-M94 Chondropathies
0.673 0.327 0.000
R59.0 Localised enlarged lymph nodes
0.672 0.328 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.672 0.328 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.671 0.328 0.000
I77 Other disorders of arteries and arterioles
0.670 0.330 0.000
M20.2 Hallux rigidus
0.670 0.330 0.000
I00-I02 Acute rheumatic fever
0.669 0.331 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.666 0.334 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.666 0.334 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.665 0.335 0.000
R25 Abnormal involuntary movements
0.664 0.336 0.000
R59.9 Enlarged lymph nodes, unspecified
0.664 0.336 0.000
R47-R49 Symptoms and signs involving speech and voice
0.664 0.336 0.000
I12.0 Hypertensive renal disease with renal failure
0.660 0.340 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.660 0.340 0.000
I63.8 Other cerebral infarction
0.659 0.341 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.659 0.341 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.659 0.341 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.659 0.341 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.659 0.341 0.000
D55-D59 Haemolytic anaemias
0.658 0.342 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.656 0.344 0.000
D72 Other disorders of white blood cells
0.654 0.345 0.000
M60-M63 Disorders of muscles
0.653 0.347 0.000
M00-M03 Infectious arthropathies
0.653 0.347 0.000
D50-D53 Nutritional anaemias
0.653 0.347 0.000
M05 Seropositive rheumatoid arthritis
0.651 0.349 0.000
M20.3 Other deformity of hallux (acquired)
0.650 0.350 0.000
G96 Other disorders of central nervous system
0.650 0.350 0.000
S20-S29 Injuries to the thorax
0.649 0.351 0.000
H43-H45 Disorders of vitreous body and globe
0.649 0.351 0.000
I22 Subsequent myocardial infarction
0.648 0.352 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.648 0.352 0.000
A30-A49 Other bacterial diseases
0.647 0.353 0.000
M14 Arthropathies in other diseases classified elsewhere
0.647 0.353 0.000
M12 Other specific arthropathies
0.647 0.353 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.647 0.353 0.000
M08 Juvenile arthritis
0.647 0.353 0.000
M06.8 Other specified rheumatoid arthritis
0.644 0.355 0.000
M06.3 Rheumatoid nodule
0.644 0.355 0.000
M06.2 Rheumatoid bursitis
0.644 0.355 0.000
M06.1 Adult-onset Still's disease
0.644 0.355 0.000
M06.0 Seronegative rheumatoid arthritis
0.644 0.355 0.000
Q80-Q89 Other congenital malformations
0.644 0.355 0.000
G40-G47 Episodic and paroxysmal disorders
0.644 0.356 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.643 0.357 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.642 0.358 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.642 0.358 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.642 0.358 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.642 0.358 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.642 0.358 0.000
Chapter XX External causes of morbidity and mortality
0.642 0.358 0.000
G93.3 Postviral fatigue syndrome
0.641 0.359 0.000
F30-F39 Mood [affective] disorders
0.640 0.360 0.000
R21 Rash and other nonspecific skin eruption
0.640 0.360 0.000
R79 Other abnormal findings of blood chemistry
0.640 0.360 0.000
H10-H13 Disorders of conjunctiva
0.639 0.360 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.638 0.362 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.638 0.362 0.000
I67.5 Moyamoya disease
0.638 0.362 0.000
I67.4 Hypertensive encephalopathy
0.638 0.362 0.000
I67.3 Progressive vascular leukoencephalopathy
0.638 0.362 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.638 0.362 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.637 0.363 0.000
D74 Methaemoglobinaemia
0.637 0.363 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.637 0.363 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.637 0.363 0.000
D69.6 Thrombocytopenia, unspecified
0.636 0.364 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.635 0.365 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.633 0.367 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.633 0.367 0.000
H49 Paralytic strabismus
0.632 0.368 0.000
G70-G73 Diseases of myoneural junction and muscle
0.632 0.368 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.631 0.369 0.000
I25 Chronic ischaemic heart disease
0.631 0.369 0.000
M11 Other crystal arthropathies
0.631 0.369 0.000
I61 Intracerebral haemorrhage
0.630 0.369 0.000
F99-F99 Unspecified mental disorder
0.629 0.371 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.629 0.371 0.000
F80-F89 Disorders of psychological development
0.629 0.371 0.000
F70-F79 Mental retardation
0.629 0.371 0.000
F60-F69 Disorders of adult personality and behaviour
0.629 0.371 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.629 0.371 0.000
Q60-Q64 Congenital malformations of the urinary system
0.628 0.372 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.628 0.372 0.000
D75.1 Secondary polycythaemia
0.627 0.373 0.000
I23 Certain current complications following acute myocardial infarction
0.626 0.374 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.624 0.376 0.000
R61 Hyperhidrosis
0.624 0.376 0.000
H55-H59 Other disorders of eye and adnexa
0.623 0.377 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.623 0.377 0.000
G93.5 Compression of brain
0.623 0.377 0.000
F41.1 Generalised anxiety disorder
0.622 0.378 0.000
E78.0 Pure hypercholesterolaemia
0.622 0.378 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.620 0.380 0.000
I20.1 Angina pectoris with documented spasm
0.618 0.381 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.618 0.382 0.000
I74 Arterial embolism and thrombosis
0.615 0.385 0.000
M40-M43 Deforming dorsopathies
0.614 0.386 0.000
I08 Multiple valve diseases
0.614 0.386 0.000
M21 Other acquired deformities of limbs
0.614 0.386 0.000
H52 Disorders of refraction and accommodation
0.614 0.386 0.000
D73 Diseases of spleen
0.613 0.387 0.000
I62 Other nontraumatic intracranial haemorrhage
0.612 0.387 0.000
I67.8 Other specified cerebrovascular diseases
0.612 0.388 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.611 0.389 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.610 0.390 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.609 0.390 0.000
M22 Disorders of patella
0.609 0.391 0.000
M34 Systemic sclerosis
0.609 0.391 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.608 0.392 0.000
R29.6 Tendency to fall, not elsewhere classified
0.607 0.393 0.000
G30-G32 Other degenerative diseases of the nervous system
0.607 0.393 0.000
B99-B99 Other infectious diseases
0.606 0.394 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.606 0.394 0.000
B65-B83 Helminthiases
0.606 0.394 0.000
B50-B64 Protozoal diseases
0.606 0.394 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.606 0.394 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.606 0.394 0.000
A80-A89 Viral infections of the central nervous system
0.606 0.394 0.000
A75-A79 Rickettsioses
0.606 0.394 0.000
A70-A74 Other diseases caused by chlamydiae
0.606 0.394 0.000
A65-A69 Other spirochaetal diseases
0.606 0.394 0.000
A20-A28 Certain zoonotic bacterial diseases
0.606 0.394 0.000
A15-A19 Tuberculosis
0.606 0.394 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.606 0.394 0.000
G93.6 Cerebral oedema
0.606 0.394 0.000
D75.2 Essential thrombocytosis
0.605 0.395 0.000
F48 Other neurotic disorders
0.605 0.395 0.000
F44 Dissociative [conversion] disorders
0.605 0.395 0.000
F42 Obsessive-compulsive disorder
0.605 0.395 0.000
B25-B34 Other viral diseases
0.605 0.395 0.000
M89 Other disorders of bone
0.604 0.396 0.000
E70-E90 Metabolic disorders
0.604 0.396 0.000
H65-H75 Diseases of middle ear and mastoid
0.602 0.398 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.601 0.399 0.000
I71 Aortic aneurysm and dissection
0.601 0.399 0.000
H51 Other disorders of binocular movement
0.601 0.399 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.601 0.399 0.000
I78 Diseases of capillaries
0.598 0.402 0.000
D80 Immunodeficiency with predominantly antibody defects
0.596 0.404 0.000
F41.8 Other specified anxiety disorders
0.595 0.405 0.000
F41.3 Other mixed anxiety disorders
0.595 0.405 0.000
M65-M68 Disorders of synovium and tendon
0.594 0.406 0.000
H50.8 Other specified strabismus
0.593 0.407 0.000
H50.6 Mechanical strabismus
0.593 0.407 0.000
H50.5 Heterophoria
0.593 0.407 0.000
H50.4 Other and unspecified heterotropia
0.593 0.407 0.000
H50.3 Intermittent heterotropia
0.593 0.407 0.000
H50.2 Vertical strabismus
0.593 0.407 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.592 0.408 0.000
Q50-Q56 Congenital malformations of genital organs
0.592 0.408 0.000
Q35-Q37 Cleft lip and cleft palate
0.592 0.408 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.592 0.408 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.592 0.408 0.000
Q00-Q07 Congenital malformations of the nervous system
0.592 0.408 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.591 0.409 0.000
M33 Dermatopolymyositis
0.591 0.409 0.000
M32 Systemic lupus erythematosus
0.591 0.409 0.000
M30 Polyarteritis nodosa and related conditions
0.591 0.409 0.000
B02 Zoster [herpes zoster]
0.590 0.410 0.000
M07.3 Other psoriatic arthropathies
0.587 0.413 0.000
D68 Other coagulation defects
0.585 0.415 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.583 0.417 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.583 0.417 0.000
D67 Hereditary factor IX deficiency
0.582 0.418 0.000
D66 Hereditary factor VIII deficiency
0.582 0.418 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.582 0.418 0.000
F43 Reaction to severe stress, and adjustment disorders
0.582 0.418 0.000
F01 Vascular dementia
0.582 0.418 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.582 0.418 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.581 0.419 0.000
M10 Gout
0.581 0.419 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.581 0.419 0.000
R68 Other general symptoms and signs
0.580 0.419 0.000
G20-G26 Extrapyramidal and movement disorders
0.579 0.421 0.000
H53.0 Amblyopia ex anopsia
0.578 0.422 0.000
S80-S89 Injuries to the knee and lower leg
0.578 0.422 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.577 0.423 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.575 0.425 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.574 0.426 0.000
F41.2 Mixed anxiety and depressive disorder
0.574 0.426 0.000
B35-B49 Mycoses
0.574 0.426 0.000
H53.9 Visual disturbance, unspecified
0.574 0.426 0.000
G95 Other diseases of spinal cord
0.571 0.429 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.571 0.429 0.000
G90 Disorders of autonomic nervous system
0.571 0.429 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.571 0.429 0.000
G92 Toxic encephalopathy
0.571 0.429 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.570 0.430 0.000
I72 Other aneurysm
0.570 0.430 0.000
S60-S69 Injuries to the wrist and hand
0.568 0.432 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.567 0.433 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.567 0.433 0.000
I05 Rheumatic mitral valve diseases
0.567 0.433 0.000
I15 Secondary hypertension
0.567 0.433 0.000
I13 Hypertensive heart and renal disease
0.567 0.433 0.000
I11 Hypertensive heart disease
0.567 0.433 0.000
F40 Phobic anxiety disorders
0.567 0.433 0.000
R27 Other lack of coordination
0.567 0.433 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.566 0.434 0.000
B07 Viral warts
0.565 0.435 0.000
R79.0 Abnormal level of blood mineral
0.565 0.435 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.565 0.435 0.000
R62 Lack of expected normal physiological development
0.565 0.435 0.000
R57 Shock, not elsewhere classified
0.565 0.435 0.000
R64 Cachexia
0.565 0.435 0.000
R58 Haemorrhage, not elsewhere classified
0.565 0.435 0.000
R50 Fever of unknown origin
0.564 0.436 0.000
D60-D64 Aplastic and other anaemias
0.563 0.437 0.000
R45 Symptoms and signs involving emotional state
0.561 0.439 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.560 0.440 0.000
M31 Other necrotising vasculopathies
0.560 0.440 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.559 0.441 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.559 0.441 0.000
I70 Atherosclerosis
0.558 0.442 0.000
E20-E35 Disorders of other endocrine glands
0.557 0.443 0.000
S90-S99 Injuries to the ankle and foot
0.557 0.443 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.554 0.446 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.554 0.446 0.000
G44 Other headache syndromes
0.553 0.447 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.552 0.447 0.000
D75.0 Familial erythrocytosis
0.552 0.447 0.000
G93.0 Cerebral cysts
0.552 0.447 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.551 0.449 0.000
F33 Recurrent depressive disorder
0.551 0.449 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.551 0.449 0.000
M20.1 Hallux valgus (acquired)
0.550 0.450 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.549 0.451 0.000
T79-T79 Certain early complications of trauma
0.549 0.451 0.000
H60-H62 Diseases of external ear
0.549 0.451 0.000
B15 Acute hepatitis A
0.548 0.452 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.546 0.454 0.000
I25.1 Atherosclerotic heart disease
0.546 0.454 0.000
G96.0 Cerebrospinal fluid leak
0.545 0.455 0.000
M80 Osteoporosis with pathological fracture
0.542 0.458 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.541 0.459 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.541 0.459 0.000
T31 Burns classified according to extent of body surface involved
0.541 0.459 0.000
R40 Somnolence, stupor and coma
0.540 0.460 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.539 0.460 0.000
I99 Other and unspecified disorders of circulatory system
0.539 0.461 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.539 0.461 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.539 0.461 0.000
R26 Abnormalities of gait and mobility
0.537 0.463 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.536 0.464 0.000
B18 Chronic viral hepatitis
0.536 0.464 0.000
M20.0 Deformity of finger(s)
0.535 0.465 0.000
R23 Other skin changes
0.535 0.465 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.535 0.465 0.000
M77 Other enthesopathies
0.534 0.466 0.000
R74 Abnormal serum enzyme levels
0.534 0.466 0.000
H53.2 Diplopia
0.534 0.466 0.000
G93.8 Other specified disorders of brain
0.533 0.467 0.000
G93.7 Reye's syndrome
0.533 0.467 0.000
G93.4 Encephalopathy, unspecified
0.533 0.467 0.000
G93.2 Benign intracranial hypertension
0.533 0.467 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.533 0.467 0.000
M24.5 Contracture of joint
0.533 0.467 0.000
I09 Other rheumatic heart diseases
0.533 0.467 0.000
I06 Rheumatic aortic valve diseases
0.533 0.467 0.000
M84 Disorders of continuity of bone
0.533 0.467 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.532 0.468 0.000
H53.4 Visual field defects
0.531 0.469 0.000
F45 Somatoform disorders
0.531 0.469 0.000
S22.4 Multiple fractures of ribs
0.531 0.469 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.530 0.470 0.000
T33-T35 Frostbite
0.529 0.471 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.529 0.471 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.529 0.471 0.000
T00-T07 Injuries involving multiple body regions
0.529 0.471 0.000
S10-S19 Injuries to the neck
0.529 0.471 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.529 0.471 0.000
G37 Other demyelinating diseases of central nervous system
0.528 0.472 0.000
F00 Dementia in Alzheimer's disease
0.528 0.472 0.000
R82 Other abnormal findings in urine
0.528 0.472 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.528 0.472 0.000
T66-T78 Other and unspecified effects of external causes
0.527 0.473 0.000
D69.9 Haemorrhagic condition, unspecified
0.527 0.473 0.000
D69.8 Other specified haemorrhagic conditions
0.527 0.473 0.000
D69.5 Secondary thrombocytopenia
0.527 0.473 0.000
D69.4 Other primary thrombocytopenia
0.527 0.473 0.000
D69.2 Other nonthrombocytopenic purpura
0.527 0.473 0.000
D69.1 Qualitative platelet defects
0.527 0.473 0.000
D69.0 Allergic purpura
0.527 0.473 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.525 0.475 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.522 0.477 0.000
R77 Other abnormalities of plasma proteins
0.522 0.477 0.000
R76 Other abnormal immunological findings in serum
0.522 0.477 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.522 0.477 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.522 0.477 0.000
R71 Abnormality of red blood cells
0.522 0.477 0.000
M25 Other joint disorders, not elsewhere classified
0.521 0.479 0.000
M90 Osteopathies in diseases classified elsewhere
0.520 0.480 0.000
M88 Paget's disease of bone [osteitis deformans]
0.520 0.480 0.000
R25.1 Tremor, unspecified
0.520 0.480 0.000
T93 Sequelae of injuries of lower limb
0.520 0.480 0.000
G91 Hydrocephalus
0.519 0.480 0.000
I77.6 Arteritis, unspecified
0.519 0.480 0.000
I10 Essential (primary) hypertension
0.519 0.481 0.000
F20 Schizophrenia
0.517 0.483 0.000
G93.9 Disorder of brain, unspecified
0.517 0.483 0.000
S32 Fracture of lumbar spine and pelvis
0.517 0.483 0.000
R69 Unknown and unspecified causes of morbidity
0.517 0.483 0.000
M89.9 Disorder of bone, unspecified
0.516 0.483 0.000
M86 Osteomyelitis
0.516 0.484 0.000
I73 Other peripheral vascular diseases
0.516 0.484 0.000
R20 Disturbances of skin sensation
0.516 0.484 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.515 0.485 0.000
R47 Speech disturbances, not elsewhere classified
0.515 0.485 0.000
M07.6 Other enteropathic arthropathies
0.515 0.485 0.000
M07.5 Arthropathy in ulcerative colitis
0.515 0.485 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.515 0.485 0.000
M07.2 Psoriatic spondylitis
0.515 0.485 0.000
M07.1 Arthritis mutilans
0.515 0.485 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.515 0.485 0.000
Q82 Other congenital malformations of skin
0.515 0.485 0.000
I08.0 Disorders of both mitral and aortic valves
0.515 0.485 0.000
M13 Other arthritis
0.514 0.486 0.000
M35 Other systemic involvement of connective tissue
0.514 0.486 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.513 0.487 0.000
B06 Rubella [German measles]
0.513 0.487 0.000
B05 Measles
0.513 0.487 0.000
B01 Varicella [chickenpox]
0.513 0.487 0.000
B00 Herpesviral [herpes simplex] infections
0.513 0.487 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.513 0.487 0.000
B04 Monkeypox
0.513 0.487 0.000
B03 Smallpox
0.513 0.487 0.000
R59.1 Generalised enlarged lymph nodes
0.513 0.487 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.512 0.488 0.000
F29 Unspecified nonorganic psychosis
0.512 0.488 0.000
M85 Other disorders of bone density and structure
0.512 0.488 0.000
H40-H42 Glaucoma
0.512 0.488 0.000
R54 Senility
0.510 0.489 0.000
T92 Sequelae of injuries of upper limb
0.510 0.489 0.000
H43 Disorders of vitreous body
0.510 0.490 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.509 0.491 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.509 0.491 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.509 0.491 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.509 0.491 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.509 0.491 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.509 0.491 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.509 0.491 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.509 0.491 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.509 0.491 0.000
Q43 Other congenital malformations of intestine
0.509 0.491 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.508 0.492 0.000
H74 Other disorders of middle ear and mastoid
0.508 0.492 0.000
I25.2 Old myocardial infarction
0.508 0.492 0.000
D84 Other immunodeficiencies
0.507 0.492 0.000
D83 Common variable immunodeficiency
0.507 0.492 0.000
D82 Immunodeficiency associated with other major defects
0.507 0.492 0.000
D81 Combined immunodeficiencies
0.507 0.492 0.000
H52.0 Hypermetropia
0.507 0.493 0.000
Q23 Congenital malformations of aortic and mitral valves
0.507 0.493 0.000
R61.9 Hyperhidrosis, unspecified
0.507 0.493 0.000
M87 Osteonecrosis
0.506 0.494 0.000
T23 Burn and corrosion of wrist and hand
0.505 0.495 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.505 0.495 0.000
F02 Dementia in other diseases classified elsewhere
0.505 0.495 0.000
F09 Unspecified organic or symptomatic mental disorder
0.505 0.495 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.505 0.495 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.504 0.496 0.000
H53.8 Other visual disturbances
0.504 0.496 0.000
W20-W49 Exposure to inanimate mechanical forces
0.503 0.496 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.503 0.497 0.000
R56 Convulsions, not elsewhere classified
0.503 0.497 0.000
T20 Burn and corrosion of head and neck
0.503 0.497 0.000
S50-S59 Injuries to the elbow and forearm
0.503 0.497 0.000
M94 Other disorders of cartilage
0.503 0.497 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.503 0.497 0.000
F03 Unspecified dementia
0.502 0.498 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.502 0.498 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.500 0.500 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.500 0.500 0.000
B02.9 Zoster without complication
0.500 0.500 0.000
M83 Adult osteomalacia
0.500 0.500 0.000
M82 Osteoporosis in diseases classified elsewhere
0.500 0.500 0.000
I60.8 Other subarachnoid haemorrhage
0.499 0.501 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.499 0.501 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.499 0.501 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.499 0.501 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.499 0.501 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.499 0.501 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.499 0.501 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.499 0.501 0.000
R30-R39 Symptoms and signs involving the urinary system
0.499 0.501 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.498 0.502 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.498 0.502 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.498 0.502 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.498 0.502 0.000
S70-S79 Injuries to the hip and thigh
0.497 0.502 0.000
S22.40 Multiple fractures of ribs (closed)
0.497 0.503 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.496 0.504 0.000
H65 Nonsuppurative otitis media
0.495 0.505 0.000
B19 Unspecified viral hepatitis
0.494 0.505 0.000
B17 Other acute viral hepatitis
0.494 0.505 0.000
B16 Acute hepatitis B
0.494 0.505 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.494 0.506 0.000
F01.9 Vascular dementia, unspecified
0.494 0.506 0.000
R46 Symptoms and signs involving appearance and behaviour
0.494 0.506 0.000
R43 Disturbances of smell and taste
0.494 0.506 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.493 0.507 0.000
R49 Voice disturbances
0.493 0.507 0.000
V80-V89 Other land transport accidents
0.493 0.507 0.000
M45-M49 Spondylopathies
0.493 0.507 0.000
R73 Elevated blood glucose level
0.492 0.507 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.492 0.508 0.000
I77.1 Stricture of artery
0.492 0.508 0.000
M76 Enthesopathies of lower limb, excluding foot
0.491 0.509 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.491 0.509 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.491 0.509 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.490 0.509 0.001
S27 Injury of other and unspecified intrathoracic organs
0.490 0.510 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.490 0.510 0.000
A46 Erysipelas
0.490 0.510 0.000
A41 Other septicaemia
0.489 0.510 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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