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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs8192591
log Bayes Factor = 69.5055
Chromosome 6   position 32,185,796  (GRCh37) Explore rs8192591 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
J33 Nasal polyp
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.000 1.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
F30-F39 Mood [affective] disorders
1.000 0.000 0.000
J47 Bronchiectasis
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.003 0.997
Chapter II Neoplasms
0.997 0.003 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.997 0.003 0.000
L40-L45 Papulosquamous disorders
0.996 0.004 0.000
E03 Other hypothyroidism
0.000 0.004 0.996
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.996 0.004 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.995 0.005 0.000
E00-E07 Disorders of thyroid gland
0.000 0.006 0.994
F32 Depressive episode
0.992 0.008 0.000
C15-C26 Malignant neoplasms of digestive organs
0.990 0.010 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.010 0.990
T39.1 4-Aminophenol derivatives
0.989 0.011 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.988 0.012 0.000
G40-G47 Episodic and paroxysmal disorders
0.987 0.013 0.000
J33.0 Polyp of nasal cavity
0.000 0.016 0.984
F41 Other anxiety disorders
0.982 0.018 0.000
G56 Mononeuropathies of upper limb
0.981 0.019 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.019 0.981
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.977 0.023 0.000
F32.9 Depressive episode, unspecified
0.975 0.025 0.000
G56.0 Carpal tunnel syndrome
0.975 0.025 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.974 0.026 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.967 0.033 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.965 0.035 0.000
G40 Epilepsy
0.965 0.035 0.000
C18 Malignant neoplasm of colon
0.959 0.041 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.959 0.041 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.958 0.042 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.957 0.043 0.000
F31 Bipolar affective disorder
0.956 0.044 0.000
C18.7 Sigmoid colon
0.956 0.044 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.955 0.045 0.000
F60-F69 Disorders of adult personality and behaviour
0.953 0.047 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.952 0.048 0.000
J33.8 Other polyp of sinus
0.000 0.049 0.951
L40.0 Psoriasis vulgaris
0.949 0.051 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.057 0.943
T43.2 Other and unspecified antidepressants
0.941 0.059 0.000
F41.2 Mixed anxiety and depressive disorder
0.931 0.069 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.927 0.073 0.000
T51 Toxic effect of alcohol
0.923 0.077 0.000
J44 Other chronic obstructive pulmonary disease
0.000 0.078 0.922
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.914 0.086 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.911 0.089 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.911 0.089 0.000
F17.1 Harmful use
0.908 0.092 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.906 0.094 0.000
F33 Recurrent depressive disorder
0.905 0.095 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.096 0.904
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.903 0.097 0.000
F60 Specific personality disorders
0.901 0.099 0.000
G51 Facial nerve disorders
0.901 0.099 0.000
T51.0 Ethanol
0.892 0.108 0.000
E07 Other disorders of thyroid
0.000 0.109 0.891
F17.2 Dependence syndrome
0.889 0.111 0.000
C21 Malignant neoplasm of anus and anal canal
0.888 0.112 0.000
G90-G99 Other disorders of the nervous system
0.888 0.112 0.000
G70-G73 Diseases of myoneural junction and muscle
0.887 0.113 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.887 0.113 0.000
F45 Somatoform disorders
0.886 0.114 0.000
J32 Chronic sinusitis
0.000 0.120 0.880
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.879 0.121 0.000
C20 Malignant neoplasm of rectum
0.875 0.125 0.000
F30 Manic episode
0.872 0.128 0.000
F31.9 Bipolar affective disorder, unspecified
0.871 0.129 0.000
G45.3 Amaurosis fugax
0.868 0.132 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.133 0.867
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.866 0.134 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.865 0.135 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.137 0.863
Chapter XXII Codes for special purposes
0.862 0.138 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.856 0.144 0.000
F44 Dissociative [conversion] disorders
0.855 0.145 0.000
G20-G26 Extrapyramidal and movement disorders
0.855 0.145 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.848 0.152 0.000
F32.1 Moderate depressive episode
0.844 0.156 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.157 0.843
T42.4 Benzodiazepines
0.842 0.158 0.000
S32 Fracture of lumbar spine and pelvis
0.842 0.158 0.000
Chapter I Certain infectious and parasitic diseases
0.840 0.160 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.164 0.836
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.835 0.165 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.833 0.167 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.833 0.167 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.832 0.168 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.831 0.169 0.000
J42 Unspecified chronic bronchitis
0.000 0.177 0.823
Chapter IV Endocrine, nutritional and metabolic diseases
0.141 0.177 0.681
F60.9 Personality disorder, unspecified
0.821 0.179 0.000
J60-J70 Lung diseases due to external agents
0.000 0.179 0.821
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.819 0.180 0.000
D00-D09 In situ neoplasms
0.817 0.183 0.000
C18.9 Colon, unspecified
0.816 0.184 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.813 0.187 0.000
F41.1 Generalised anxiety disorder
0.812 0.188 0.000
J32.0 Chronic maxillary sinusitis
0.000 0.188 0.812
C64-C68 Malignant neoplasms of urinary tract
0.811 0.189 0.000
Q80-Q89 Other congenital malformations
0.809 0.190 0.000
J84 Other interstitial pulmonary diseases
0.000 0.191 0.809
F42 Obsessive-compulsive disorder
0.809 0.191 0.000
F45.8 Other somatoform disorders
0.808 0.192 0.000
L50-L54 Urticaria and erythema
0.807 0.193 0.000
G70 Myasthenia gravis and other myoneural disorders
0.802 0.198 0.000
J30 Vasomotor and allergic rhinitis
0.000 0.198 0.802
F31.8 Other bipolar affective disorders
0.801 0.199 0.000
C21.1 Anal canal
0.800 0.200 0.000
M07.3 Other psoriatic arthropathies
0.798 0.200 0.002
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.799 0.201 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.799 0.201 0.000
S40-S49 Injuries to the shoulder and upper arm
0.797 0.203 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.797 0.203 0.000
S10-S19 Injuries to the neck
0.796 0.204 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.793 0.206 0.000
T39.0 Salicylates
0.793 0.207 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.793 0.207 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.787 0.213 0.000
C51-C58 Malignant neoplasms of female genital organs
0.786 0.214 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.786 0.214 0.000
F60.3 Emotionally unstable personality disorder
0.784 0.216 0.000
G40.5 Special epileptic syndromes
0.784 0.216 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.783 0.217 0.000
M07 Psoriatic and enteropathic arthropathies
0.766 0.218 0.016
J45.0 Predominantly allergic asthma
0.000 0.219 0.781
M05-M14 Inflammatory polyarthropathies
0.743 0.221 0.036
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.776 0.224 0.000
F69 Unspecified disorder of adult personality and behaviour
0.774 0.226 0.000
G51.0 Bell's palsy
0.774 0.226 0.000
E10-E14 Diabetes mellitus
0.099 0.226 0.674
E06 Thyroiditis
0.000 0.227 0.772
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.771 0.229 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.771 0.229 0.000
Q50-Q56 Congenital malformations of genital organs
0.771 0.229 0.000
F41.9 Anxiety disorder, unspecified
0.770 0.230 0.000
G56.1 Other lesions of median nerve
0.769 0.231 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.769 0.231 0.000
C82.0 Small cleaved cell, follicular
0.765 0.235 0.000
G93 Other disorders of brain
0.765 0.235 0.000
J31.0 Chronic rhinitis
0.000 0.235 0.765
J34 Other disorders of nose and nasal sinuses
0.000 0.237 0.763
C25 Malignant neoplasm of pancreas
0.763 0.237 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.762 0.238 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.762 0.238 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.761 0.239 0.000
B35-B49 Mycoses
0.760 0.240 0.000
J81 Pulmonary oedema
0.000 0.240 0.760
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.758 0.242 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.758 0.242 0.000
G56.2 Lesion of ulnar nerve
0.757 0.243 0.000
C17 Malignant neoplasm of small intestine
0.756 0.244 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.754 0.246 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.751 0.249 0.000
J36 Peritonsillar abscess
0.000 0.250 0.750
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.743 0.251 0.006
T79-T79 Certain early complications of trauma
0.748 0.252 0.000
S32.4 Fracture of acetabulum
0.748 0.252 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.745 0.255 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.745 0.255 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.744 0.256 0.000
G96 Other disorders of central nervous system
0.742 0.257 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.259 0.741
G70.0 Myasthenia gravis
0.740 0.260 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.738 0.262 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.738 0.262 0.000
G40.8 Other epilepsy
0.738 0.262 0.000
Q60-Q64 Congenital malformations of the urinary system
0.738 0.262 0.000
G51.3 Clonic hemifacial spasm
0.737 0.263 0.000
F32.0 Mild depressive episode
0.736 0.264 0.000
F33.9 Recurrent depressive disorder, unspecified
0.736 0.264 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.734 0.266 0.000
S90-S99 Injuries to the ankle and foot
0.733 0.267 0.000
T51.9 Alcohol, unspecified
0.732 0.268 0.000
F40 Phobic anxiety disorders
0.731 0.269 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.727 0.273 0.000
F30.0 Hypomania
0.724 0.276 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.723 0.277 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.721 0.279 0.000
F30.9 Manic episode, unspecified
0.720 0.280 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.281 0.719
S70-S79 Injuries to the hip and thigh
0.717 0.283 0.000
L40.8 Other psoriasis
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
L40.1 Generalised pustular psoriasis
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
J45.8 Mixed asthma
0.000 0.283 0.717
J45.1 Nonallergic asthma
0.000 0.283 0.717
J37 Chronic laryngitis and laryngotracheitis
0.000 0.283 0.717
F38 Other mood [affective] disorders
0.717 0.283 0.000
F34 Persistent mood [affective] disorders
0.717 0.283 0.000
F39 Unspecified mood [affective] disorder
0.717 0.283 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.715 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.285 0.000
F48 Other neurotic disorders
0.714 0.285 0.000
L44 Other papulosquamous disorders
0.714 0.286 0.000
L41 Parapsoriasis
0.714 0.286 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.714 0.286 0.000
L42 Pityriasis rosea
0.714 0.286 0.000
E03.8 Other specified hypothyroidism
0.000 0.286 0.714
E03.5 Myxoedema coma
0.000 0.286 0.714
E03.4 Atrophy of thyroid (acquired)
0.000 0.286 0.714
E03.3 Postinfectious hypothyroidism
0.000 0.286 0.714
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.286 0.714
E03.1 Congenital hypothyroidism without goitre
0.000 0.286 0.714
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.286 0.714
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.714 0.286 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.714 0.286 0.000
T39.4 Antirheumatics, not elsewhere classified
0.714 0.286 0.000
T39.2 Pyrazolone derivatives
0.714 0.286 0.000
L10-L14 Bullous disorders
0.713 0.287 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.713 0.287 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.287 0.712
E00 Congenital iodine-deficiency syndrome
0.000 0.287 0.712
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.287 0.712
T50.9 Other and unspecified drugs, medicaments and biological substances
0.712 0.288 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.712 0.288 0.000
F32.8 Other depressive episodes
0.711 0.289 0.000
C23 Malignant neoplasm of gallbladder
0.710 0.290 0.000
E05.8 Other thyrotoxicosis
0.000 0.290 0.710
E05.5 Thyroid crisis or storm
0.000 0.290 0.710
E05.4 Thyrotoxicosis factitia
0.000 0.290 0.710
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.290 0.710
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.290 0.710
T47.1 Other antacids and anti-gastric-secretion drugs
0.710 0.290 0.000
G24 Dystonia
0.709 0.291 0.000
G54 Nerve root and plexus disorders
0.708 0.292 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.708 0.292 0.000
G52 Disorders of other cranial nerves
0.708 0.292 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.707 0.293 0.000
G51.9 Disorder of facial nerve, unspecified
0.707 0.293 0.000
G90 Disorders of autonomic nervous system
0.706 0.294 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.705 0.294 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.705 0.295 0.000
B37 Candidiasis
0.705 0.295 0.000
F41.8 Other specified anxiety disorders
0.704 0.295 0.000
F41.3 Other mixed anxiety disorders
0.704 0.295 0.000
G61 Inflammatory polyneuropathy
0.704 0.296 0.000
Chapter VIII Diseases of the ear and mastoid process
0.704 0.296 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.703 0.296 0.000
G56.4 Causalgia
0.703 0.296 0.000
G56.3 Lesion of radial nerve
0.703 0.296 0.000
G45.4 Transient global amnesia
0.703 0.297 0.000
E10 Insulin-dependent diabetes mellitus
0.013 0.297 0.690
G58 Other mononeuropathies
0.703 0.297 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.703 0.297 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.298 0.702
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.701 0.299 0.000
Q21 Congenital malformations of cardiac septa
0.701 0.299 0.000
F44.5 Dissociative convulsions
0.700 0.300 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.700 0.300 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.700 0.300 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.700 0.300 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.700 0.300 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.700 0.300 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.700 0.300 0.000
F11 Mental and behavioural disorders due to use of opioids
0.700 0.300 0.000
J00-J06 Acute upper respiratory infections
0.000 0.300 0.700
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.700 0.300 0.000
G20 Parkinson's disease
0.700 0.300 0.000
F80-F89 Disorders of psychological development
0.699 0.300 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.699 0.301 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.698 0.302 0.000
C95 Leukaemia of unspecified cell type
0.698 0.302 0.000
C94 Other leukaemias of specified cell type
0.698 0.302 0.000
C93 Monocytic leukaemia
0.698 0.302 0.000
C88 Malignant immunoproliferative diseases
0.698 0.302 0.000
C86 Other specified types of T/NK-cell lymphoma
0.698 0.302 0.000
J34.2 Deviated nasal septum
0.000 0.302 0.698
G91 Hydrocephalus
0.697 0.303 0.000
F44.9 Dissociative [conversion] disorder, unspecified
0.697 0.303 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.696 0.303 0.000
J46 Status asthmaticus
0.000 0.304 0.696
D05 Carcinoma in situ of breast
0.695 0.305 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.693 0.307 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.693 0.307 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.693 0.307 0.000
G45.0 Vertebro-basilar artery syndrome
0.693 0.307 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.693 0.307 0.000
G50 Disorders of trigeminal nerve
0.693 0.307 0.000
T43.9 Psychotropic drug, unspecified
0.692 0.308 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.692 0.308 0.000
T43.6 Psychostimulants with abuse potential
0.692 0.308 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.692 0.308 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.692 0.308 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.692 0.308 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.692 0.308 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.691 0.309 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.690 0.310 0.000
Q00-Q07 Congenital malformations of the nervous system
0.689 0.311 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.689 0.311 0.000
C18.8 Overlapping lesion of colon
0.688 0.312 0.000
C18.1 Appendix
0.688 0.312 0.000
E10.9 Without complications
0.000 0.312 0.687
F17.9 Unspecified mental and behavioural disorder
0.687 0.313 0.000
F17.8 Other mental and behavioural disorders
0.687 0.313 0.000
F17.7 Residual and late-onset psychotic disorder
0.687 0.313 0.000
F17.6 Amnesic syndrome
0.687 0.313 0.000
F17.5 Psychotic disorder
0.687 0.313 0.000
F17.4 Withdrawal state with delirium
0.687 0.313 0.000
F17.3 Withdrawal state
0.687 0.313 0.000
F17.0 Acute intoxication
0.687 0.313 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.687 0.313 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.687 0.313 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.687 0.313 0.000
T42.3 Barbiturates
0.687 0.313 0.000
T42.2 Succinimides and oxazolidinediones
0.687 0.313 0.000
T42.1 Iminostilbenes
0.687 0.313 0.000
T42.0 Hydantoin derivatives
0.687 0.313 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.686 0.314 0.000
Q35-Q37 Cleft lip and cleft palate
0.686 0.314 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.686 0.314 0.000
F31.7 Bipolar affective disorder, currently in remission
0.686 0.314 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.686 0.314 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.686 0.314 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.686 0.314 0.000
T65 Toxic effect of other and unspecified substances
0.685 0.315 0.000
T63 Toxic effect of contact with venomous animals
0.685 0.315 0.000
T62 Toxic effect of other noxious substances eaten as food
0.685 0.315 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.685 0.315 0.000
T60 Toxic effect of pesticides
0.685 0.315 0.000
T59 Toxic effect of other gases, fumes and vapours
0.685 0.315 0.000
T57 Toxic effect of other inorganic substances
0.685 0.315 0.000
T56 Toxic effect of metals
0.685 0.315 0.000
T54 Toxic effect of corrosive substances
0.685 0.315 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.685 0.315 0.000
T52 Toxic effect of organic solvents
0.685 0.315 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.685 0.315 0.000
T58 Toxic effect of carbon monoxide
0.685 0.315 0.000
T55 Toxic effect of soaps and detergents
0.685 0.315 0.000
L52 Erythema nodosum
0.685 0.315 0.000
F68 Other disorders of adult personality and behaviour
0.683 0.317 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.683 0.317 0.000
F65 Disorders of sexual preference
0.683 0.317 0.000
F64 Gender identity disorders
0.683 0.317 0.000
F63 Habit and impulse disorders
0.683 0.317 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.683 0.317 0.000
F61 Mixed and other personality disorders
0.683 0.317 0.000
C82.6 Cutaneous follicle centre lymphoma
0.683 0.317 0.000
C82.5 Diffuse follicle centre lymphoma
0.683 0.317 0.000
C82.4 Follicular lymphoma grade IIIb
0.683 0.317 0.000
C82.3 Follicular lymphoma grade IIIa
0.683 0.317 0.000
C82.2 Large cell, follicular
0.683 0.317 0.000
S32.1 Fracture of sacrum
0.681 0.319 0.000
S32.40 Fracture of acetabulum (closed)
0.680 0.320 0.000
S32.0 Fracture of lumbar vertebra
0.679 0.320 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.677 0.323 0.000
C21.0 Anus, unspecified
0.677 0.323 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.676 0.324 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.675 0.325 0.000
F42.9 Obsessive-compulsive disorder, unspecified
0.675 0.325 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.674 0.326 0.000
S20-S29 Injuries to the thorax
0.673 0.327 0.000
G56.8 Other mononeuropathies of upper limb
0.672 0.327 0.000
C09 Malignant neoplasm of tonsil
0.672 0.328 0.000
J30.1 Allergic rhinitis due to pollen
0.000 0.329 0.671
C22.9 Liver, unspecified
0.669 0.331 0.000
U80 Agent resistant to penicillin and related antibiotics
0.668 0.332 0.000
F10.2 Dependence syndrome
0.667 0.333 0.000
C22.1 Intrahepatic bile duct carcinoma
0.667 0.333 0.000
C91 Lymphoid leukaemia
0.666 0.334 0.000
A30-A49 Other bacterial diseases
0.665 0.335 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.336 0.664
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.664 0.336 0.000
F99-F99 Unspecified mental disorder
0.664 0.336 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.336 0.664
B50-B64 Protozoal diseases
0.664 0.336 0.000
G44 Other headache syndromes
0.663 0.337 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.663 0.337 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.661 0.338 0.001
T51.8 Other alcohols
0.662 0.338 0.000
T51.3 Fusel oil
0.662 0.338 0.000
T51.2 2-Propanol
0.662 0.338 0.000
T51.1 Methanol
0.662 0.338 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.662 0.338 0.000
C12 Malignant neoplasm of pyriform sinus
0.661 0.339 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.660 0.339 0.000
G41 Status epilepticus
0.659 0.341 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.658 0.341 0.000
J40 Bronchitis, not specified as acute or chronic
0.000 0.346 0.654
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.653 0.346 0.000
S37 Injury of urinary and pelvic organs
0.653 0.346 0.000
S36 Injury of intra-abdominal organs
0.653 0.346 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.653 0.346 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.653 0.346 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.653 0.346 0.000
S31 Open wound of abdomen, lower back and pelvis
0.653 0.346 0.000
T38.9 Other and unspecified hormone antagonists
0.653 0.347 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.653 0.347 0.000
T38.7 Androgens and anabolic congeners
0.653 0.347 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.653 0.347 0.000
T38.5 Other oestrogens and progestogens
0.653 0.347 0.000
T38.4 Oral contraceptives
0.653 0.347 0.000
T38.2 Antithyroid drugs
0.653 0.347 0.000
T38.1 Thyroid hormones and substitutes
0.653 0.347 0.000
T38.0 Glucocorticoids and synthetic analogues
0.653 0.347 0.000
G71 Primary disorders of muscles
0.652 0.348 0.000
J39 Other diseases of upper respiratory tract
0.000 0.349 0.651
B37.0 Candidal stomatitis
0.650 0.350 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.650 0.350 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.650 0.350 0.000
C85.0 Lymphosarcoma
0.650 0.350 0.000
F33.8 Other recurrent depressive disorders
0.649 0.351 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.649 0.351 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.649 0.351 0.000
C56 Malignant neoplasm of ovary
0.648 0.352 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.352 0.648
F60.8 Other specific personality disorders
0.646 0.354 0.000
F60.7 Dependent personality disorder
0.646 0.354 0.000
F60.6 Anxious [avoidant] personality disorder
0.646 0.354 0.000
F60.5 Anankastic personality disorder
0.646 0.354 0.000
F60.4 Histrionic personality disorder
0.646 0.354 0.000
F60.2 Dissocial personality disorder
0.646 0.354 0.000
F60.1 Schizoid personality disorder
0.646 0.354 0.000
F60.0 Paranoid personality disorder
0.646 0.354 0.000
G51.8 Other disorders of facial nerve
0.646 0.354 0.000
G51.4 Facial myokymia
0.646 0.354 0.000
G51.2 Melkersson's syndrome
0.646 0.354 0.000
G51.1 Geniculate ganglionitis
0.646 0.354 0.000
Q83 Congenital malformations of breast
0.644 0.355 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.644 0.356 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.643 0.357 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.643 0.357 0.000
C25.0 Head of pancreas
0.643 0.357 0.000
K90 Intestinal malabsorption
0.030 0.358 0.612
E10.3 With ophthalmic complications
0.004 0.358 0.638
B20-B24 Human immunodeficiency virus [HIV] disease
0.641 0.359 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.640 0.360 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.640 0.360 0.000
J95-J99 Other diseases of the respiratory system
0.000 0.360 0.640
J03 Acute tonsillitis
0.000 0.360 0.640
E07.1 Dyshormogenetic goitre
0.000 0.361 0.639
E07.0 Hypersecretion of calcitonin
0.000 0.361 0.639
G30-G32 Other degenerative diseases of the nervous system
0.639 0.361 0.000
S19 Other and unspecified injuries of neck
0.639 0.361 0.000
J32.9 Chronic sinusitis, unspecified
0.000 0.362 0.638
S40 Superficial injury of shoulder and upper arm
0.638 0.362 0.000
S41 Open wound of shoulder and upper arm
0.637 0.363 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.637 0.363 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.637 0.363 0.000
C21.2 Cloacogenic zone
0.637 0.363 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.636 0.363 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.636 0.363 0.000
G92 Toxic encephalopathy
0.636 0.363 0.000
G72 Other myopathies
0.636 0.363 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.636 0.364 0.000
F45.9 Somatoform disorder, unspecified
0.635 0.364 0.000
F45.4 Persistent somatoform pain disorder
0.635 0.364 0.000
F45.3 Somatoform autonomic dysfunction
0.635 0.364 0.000
F45.2 Hypochondriacal disorder
0.635 0.364 0.000
F45.1 Undifferentiated somatoform disorder
0.635 0.364 0.000
F45.0 Somatisation disorder
0.635 0.364 0.000
B65-B83 Helminthiases
0.635 0.365 0.000
Q82 Other congenital malformations of skin
0.634 0.366 0.000
A80-A89 Viral infections of the central nervous system
0.633 0.367 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.632 0.368 0.000
C34 Malignant neoplasm of bronchus and lung
0.632 0.368 0.000
J69 Pneumonitis due to solids and liquids
0.000 0.368 0.632
S60-S69 Injuries to the wrist and hand
0.631 0.369 0.000
J32.4 Chronic pansinusitis
0.000 0.369 0.631
J32.3 Chronic sphenoidal sinusitis
0.000 0.369 0.631
J32.1 Chronic frontal sinusitis
0.000 0.369 0.631
T23 Burn and corrosion of wrist and hand
0.631 0.369 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.630 0.370 0.000
C18.5 Splenic flexure
0.630 0.370 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.372 0.628
C53 Malignant neoplasm of cervix uteri
0.627 0.373 0.000
G82 Paraplegia and tetraplegia
0.627 0.373 0.000
S79 Other and unspecified injuries of hip and thigh
0.625 0.375 0.000
J32.2 Chronic ethmoidal sinusitis
0.000 0.375 0.625
F30.8 Other manic episodes
0.625 0.375 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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