TreeWAS – Variant ID: rs838886

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H53.1 Subjective visual disturbances	0.099	0.901	0.000
H53 Visual disturbances	0.087	0.913	0.000
H53.4 Visual field defects	0.087	0.913	0.000
H53.2 Diplopia	0.085	0.915	0.000
H53.5 Colour vision deficiencies	0.067	0.933	0.000
H53.6 Night blindness	0.063	0.937	0.000
H53.3 Other disorders of binocular vision	0.059	0.941	0.000
H53-H54 Visual disturbances and blindness	0.039	0.960	0.000
H53.0 Amblyopia ex anopsia	0.038	0.962	0.000
H54 Blindness and low vision	0.030	0.970	0.000
H54.0 Blindness, both eyes	0.027	0.973	0.000
Z95.1 Presence of aortocoronary bypass graft	0.025	0.975	0.000
H54.7 Unspecified visual loss	0.024	0.976	0.000
H54.1 Blindness, one eye, low vision, other eye	0.022	0.978	0.000
H54.9 Unspecified visual impairment (binocular)	0.022	0.978	0.000
H54.3 Unqualified visual loss, both eyes	0.022	0.978	0.000
H53.9 Visual disturbance, unspecified	0.021	0.979	0.000
H54.5 Low vision, one eye	0.021	0.979	0.000
H54.6 Unqualified visual loss, one eye	0.021	0.979	0.000
H54.2 Low vision, both eyes	0.020	0.980	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.012	0.988	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.012	0.988	0.000
M75.0 Adhesive capsulitis of shoulder	0.000	0.988	0.012
H54.4 Blindness, one eye	0.011	0.988	0.000
T39.1 4-Aminophenol derivatives	0.011	0.989	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.011	0.989	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.011	0.989	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.010	0.990	0.000
T43.2 Other and unspecified antidepressants	0.010	0.990	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.009	0.991	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.009	0.991	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.009	0.991	0.000
T78.2 Anaphylactic shock, unspecified	0.009	0.991	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.009	0.991	0.000
T39.4 Antirheumatics, not elsewhere classified	0.009	0.991	0.000
T39.2 Pyrazolone derivatives	0.009	0.991	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.009	0.991	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.008	0.992	0.000
T43.9 Psychotropic drug, unspecified	0.008	0.992	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.008	0.992	0.000
H53.8 Other visual disturbances	0.008	0.992	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.008	0.992	0.000
Q28 Other congenital malformations of circulatory system	0.008	0.992	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.008	0.992	0.000
Q66 Congenital deformities of feet	0.008	0.992	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.008	0.992	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.008	0.992	0.000
T43.6 Psychostimulants with abuse potential	0.008	0.992	0.000
Q51 Congenital malformations of uterus and cervix	0.008	0.992	0.000
Q51.3 Bicornate uterus	0.008	0.992	0.000
T39.0 Salicylates	0.007	0.992	0.000
Q50-Q56 Congenital malformations of genital organs	0.007	0.992	0.000
Q74 Other congenital malformations of limb(s)	0.007	0.993	0.000
Q39 Congenital malformations of oesophagus	0.007	0.993	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.007	0.993	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.007	0.993	0.000
Q43 Other congenital malformations of intestine	0.007	0.993	0.000
O36.8 Maternal care for other specified foetal problems	0.007	0.993	0.000
Q38.7 Pharyngeal pouch	0.007	0.993	0.000
Q66.8 Other congenital deformities of feet	0.007	0.993	0.000
Q78 Other osteochondrodysplasias	0.007	0.993	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.007	0.993	0.000
Q78.0 Osteogenesis imperfecta	0.007	0.993	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.007	0.993	0.000
Q66.0 Talipes equinovarus	0.007	0.993	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.007	0.993	0.000
Q40 Other congenital malformations of upper alimentary tract	0.007	0.993	0.000
F03 Unspecified dementia	0.007	0.993	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.007	0.993	0.000
T36 Poisoning by systemic antibiotics	0.007	0.993	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.007	0.993	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.007	0.993	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.007	0.993	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.007	0.993	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.007	0.993	0.000
Q66.9 Congenital deformity of feet, unspecified	0.007	0.993	0.000
T38.1 Thyroid hormones and substitutes	0.006	0.993	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.006	0.993	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.007	0.993	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.006	0.993	0.000
Q39.4 Oesophageal web	0.006	0.994	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.006	0.994	0.000
Q43.3 Congenital malformations of intestinal fixation	0.006	0.994	0.000
Q35-Q37 Cleft lip and cleft palate	0.006	0.994	0.000
Q66.7 Pes cavus	0.006	0.994	0.000
Q44.5 Other congenital malformations of bile ducts	0.006	0.994	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.006	0.994	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.006	0.994	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.006	0.994	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.006	0.994	0.000
Q65 Congenital deformities of hip	0.006	0.994	0.000
T78 Adverse effects, not elsewhere classified	0.006	0.994	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.006	0.994	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.006	0.994	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.006	0.994	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.006	0.994	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.006	0.994	0.000
Q45 Other congenital malformations of digestive system	0.006	0.994	0.000
C71.1 Frontal lobe	0.000	0.994	0.006
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.006	0.994	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.006	0.994	0.000
Q39.6 Diverticulum of oesophagus	0.006	0.994	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.006	0.994	0.000
Q75 Other congenital malformations of skull and face bones	0.006	0.994	0.000
Q73 Reduction defects of unspecified limb	0.006	0.994	0.000
Q72 Reduction defects of lower limb	0.006	0.994	0.000
Q71 Reduction defects of upper limb	0.006	0.994	0.000
Q69 Polydactyly	0.006	0.994	0.000
T46.1 Calcium-channel blockers	0.006	0.994	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.006	0.994	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.006	0.994	0.000
Q00-Q07 Congenital malformations of the nervous system	0.006	0.994	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.006	0.994	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.006	0.994	0.000
Q28.1 Other malformations of precerebral vessels	0.006	0.994	0.000
Q66.6 Other congenital valgus deformities of feet	0.006	0.994	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.006	0.994	0.000
Q74.1 Congenital malformation of knee	0.006	0.994	0.000
T40.6 Other and unspecified narcotics	0.006	0.994	0.000
Q66.5 Congenital pes planus	0.006	0.994	0.000
Q66.4 Talipes calcaneovalgus	0.006	0.994	0.000
Q66.1 Talipes calcaneovarus	0.006	0.994	0.000
Q28.3 Other malformations of cerebral vessels	0.006	0.994	0.000
Q27 Other congenital malformations of peripheral vascular system	0.006	0.994	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.006	0.994	0.000
T38.9 Other and unspecified hormone antagonists	0.006	0.994	0.000
T38.7 Androgens and anabolic congeners	0.006	0.994	0.000
T38.5 Other oestrogens and progestogens	0.006	0.994	0.000
T38.4 Oral contraceptives	0.006	0.994	0.000
T38.2 Antithyroid drugs	0.006	0.994	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.006	0.994	0.000
Q51.4 Unicornate uterus	0.006	0.994	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.006	0.994	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.006	0.994	0.000
Q51.6 Embryonic cyst of cervix	0.006	0.994	0.000
Q51.5 Agenesis and aplasia of cervix	0.006	0.994	0.000
Q51.0 Agenesis and aplasia of uterus	0.006	0.994	0.000
Q54 Hypospadias	0.006	0.994	0.000
Q66.3 Other congenital varus deformities of feet	0.006	0.994	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.006	0.994	0.000
C71.9 Brain, unspecified	0.000	0.994	0.006
T36.8 Other systemic antibiotics	0.006	0.994	0.000
Q68 Other congenital musculoskeletal deformities	0.005	0.994	0.000
Q80-Q89 Other congenital malformations	0.006	0.994	0.000
Q70 Syndactyly	0.005	0.994	0.000
F01 Vascular dementia	0.006	0.994	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.005	0.994	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.005	0.994	0.000
Q74.3 Arthrogryposis multiplex congenita	0.005	0.994	0.000
T38.0 Glucocorticoids and synthetic analogues	0.005	0.994	0.000
T78.8 Other adverse effects, not elsewhere classified	0.006	0.994	0.000
Q39.8 Other congenital malformations of oesophagus	0.005	0.994	0.000
Q39.5 Congenital dilatation of oesophagus	0.005	0.994	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.005	0.994	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.005	0.994	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.005	0.994	0.000
Q39.0 Atresia of oesophagus without fistula	0.005	0.994	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.994	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.005	0.994	0.000
Q43.8 Other specified congenital malformations of intestine	0.005	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
T46.7 Peripheral vasodilators	0.005	0.995	0.000
Q52 Other congenital malformations of female genitalia	0.005	0.995	0.000
Q40.2 Other specified congenital malformations of stomach	0.005	0.995	0.000
T68 Hypothermia	0.005	0.995	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.005	0.995	0.000
Q38.3 Other congenital malformations of tongue	0.005	0.995	0.000
Q38.2 Macroglossia	0.005	0.995	0.000
Q40.1 Congenital hiatus hernia	0.005	0.995	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.005	0.995	0.000
Q55 Other congenital malformations of male genital organs	0.005	0.995	0.000
Q43.7 Persistent cloaca	0.005	0.995	0.000
Q43.6 Congenital fistula of rectum and anus	0.005	0.995	0.000
Q43.5 Ectopic anus	0.005	0.995	0.000
Q43.4 Duplication of intestine	0.005	0.995	0.000
Q43.2 Other congenital functional disorders of colon	0.005	0.995	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.005	0.995	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.005	0.995	0.000
Q78.8 Other specified osteochondrodysplasias	0.005	0.995	0.000
Q78.6 Multiple congenital exostoses	0.005	0.995	0.000
Q78.5 Metaphyseal dysplasia	0.005	0.995	0.000
Q78.4 Enchondromatosis	0.005	0.995	0.000
Q78.3 Progressive diaphyseal dysplasia	0.005	0.995	0.000
Q78.1 Polyostotic fibrous dysplasia	0.005	0.995	0.000
Q76 Congenital malformations of spine and bony thorax	0.005	0.995	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.005	0.995	0.000
Q51.2 Other doubling of uterus	0.005	0.995	0.000
Q44.4 Choledochal cyst	0.005	0.995	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.005	0.995	0.000
Q44.2 Atresia of bile ducts	0.005	0.995	0.000
Q44.1 Other congenital malformations of gallbladder	0.005	0.995	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.005	0.995	0.000
T40.1 Heroin	0.005	0.995	0.000
Q38.8 Other congenital malformations of pharynx	0.005	0.995	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.005	0.995	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.005	0.995	0.000
C22.9 Liver, unspecified	0.005	0.995	0.000
T40.5 Cocaine	0.005	0.995	0.000
Q43.0 Meckel's diverticulum	0.005	0.995	0.000
Q30 Congenital malformations of nose	0.005	0.995	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
Q38.1 Ankyloglossia	0.005	0.995	0.000
Q44.7 Other congenital malformations of liver	0.005	0.995	0.000
T45.0 Antiallergic and antiemetic drugs	0.005	0.995	0.000
T66-T78 Other and unspecified effects of external causes	0.005	0.995	0.000
C22.1 Intrahepatic bile duct carcinoma	0.005	0.995	0.000
F01.9 Vascular dementia, unspecified	0.005	0.995	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.005	0.995	0.000
C71 Malignant neoplasm of brain	0.000	0.995	0.005
Q27.3 Peripheral arteriovenous malformation	0.005	0.995	0.000
F09 Unspecified organic or symptomatic mental disorder	0.005	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.005	0.995	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.005	0.995	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
Q31 Congenital malformations of larynx	0.005	0.995	0.000
Q43.1 Hirschsprung's disease	0.005	0.995	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.005	0.995	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.005	0.995	0.000
F02 Dementia in other diseases classified elsewhere	0.005	0.995	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.005	0.995	0.000
Q35 Cleft palate	0.005	0.995	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.005	0.995	0.000
Q85 Phakomatoses, not elsewhere classified	0.005	0.995	0.000
C22.0 Liver cell carcinoma	0.005	0.995	0.000
T36.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
T36.7 Antifungal antibiotics, systemically used	0.005	0.995	0.000
T36.6 Rifamycins	0.005	0.995	0.000
T36.5 Aminoglycosides	0.005	0.995	0.000
T36.2 Chloramphenicol group	0.005	0.995	0.000
T41.5 Therapeutic gases	0.005	0.995	0.000
T41.4 Anaesthetic, unspecified	0.005	0.995	0.000
T41.3 Local anaesthetics	0.005	0.995	0.000
T41.2 Other and unspecified general anaesthetics	0.005	0.995	0.000
T41.1 Intravenous anaesthetics	0.005	0.995	0.000
T41.0 Inhaled anaesthetics	0.005	0.995	0.000
T47.2 Stimulant laxatives	0.005	0.995	0.000
Q06 Other congenital malformations of spinal cord	0.005	0.995	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.005	0.995	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.005	0.995	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.005	0.995	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.005	0.995	0.000
T44.0 Anticholinesterase agents	0.005	0.995	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.005	0.995	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
Q37 Cleft palate with cleft lip	0.005	0.995	0.000
T49.9 Topical agent, unspecified	0.005	0.995	0.000
T49.8 Other topical agents	0.005	0.995	0.000
T49.7 Dental drugs, topically applied	0.005	0.995	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.005	0.995	0.000
T49.5 Ophthalmological drugs and preparations	0.005	0.995	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.995	0.000
T49.3 Emollients, demulcents and protectants	0.005	0.995	0.000
T49.2 Local astringents and local detergents	0.005	0.995	0.000
T49.1 Antipruritics	0.005	0.995	0.000
Q96 Turner's syndrome	0.005	0.995	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.005	0.995	0.000
Q65.9 Congenital deformity of hip, unspecified	0.005	0.995	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.005	0.995	0.000
T36.3 Macrolides	0.005	0.995	0.000
T36.0 Penicillins	0.005	0.995	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.005	0.995	0.000
T78.9 Adverse effect, unspecified	0.005	0.995	0.000
Q14 Congenital malformations of posterior segment of eye	0.005	0.995	0.000
Q44.6 Cystic disease of liver	0.005	0.995	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.005	0.995	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.005	0.995	0.000
T37.5 Antiviral drugs	0.005	0.995	0.000
T37.4 Anthelminthics	0.005	0.995	0.000
T37.3 Other antiprotozoal drugs	0.005	0.995	0.000
T37.1 Antimycobacterial drugs	0.005	0.995	0.000
T37.0 Sulphonamides	0.005	0.995	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.005	0.995	0.000
T40.8 Lysergide [LSD]	0.005	0.995	0.000
T40.7 Cannabis (derivatives)	0.005	0.995	0.000
T40.0 Opium	0.005	0.995	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.995	0.000
Q34 Other congenital malformations of respiratory system	0.005	0.995	0.000
Q33 Congenital malformations of lung	0.005	0.995	0.000
Q32 Congenital malformations of trachea and bronchus	0.005	0.995	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.005	0.995	0.000
Q50.5 Embryonic cyst of broad ligament	0.005	0.995	0.000
T47.4 Other laxatives	0.005	0.995	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.005	0.995	0.000
T36.4 Tetracyclines	0.005	0.995	0.000
Q36 Cleft lip	0.005	0.995	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.005	0.995	0.000
Q78.2 Osteopetrosis	0.005	0.995	0.000
F00 Dementia in Alzheimer's disease	0.005	0.995	0.000
Q12 Congenital lens malformations	0.005	0.995	0.000
T47.0 Histamine H(2)-receptor antagonists	0.005	0.995	0.000
Q54.1 Hypospadias, penile	0.005	0.995	0.000
Q03 Congenital hydrocephalus	0.005	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.005	0.995	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.005	0.995	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.005	0.995	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.005	0.995	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.005	0.995	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.005	0.995	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.005	0.995	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.005	0.995	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.005	0.995	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.005	0.995	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.005	0.995	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
T47.7 Emetics	0.005	0.995	0.000
T47.5 Digestants	0.005	0.995	0.000
T47.3 Saline and osmotic laxatives	0.005	0.995	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.005	0.995	0.000
Q65.6 Unstable hip	0.005	0.995	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.005	0.995	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.005	0.995	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.005	0.995	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.005	0.995	0.000
T45.4 Iron and its compounds	0.005	0.995	0.000
Q26 Congenital malformations of great veins	0.005	0.995	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.005	0.995	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.005	0.995	0.000
T40.3 Methadone	0.005	0.995	0.000
Q53 Undescended testicle	0.005	0.995	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.005	0.995	0.000
T47.6 Antidiarrhoeal drugs	0.005	0.995	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.005	0.995	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.005	0.995	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.005	0.995	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.005	0.995	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.005	0.995	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.005	0.995	0.000
Q66.2 Metatarsus varus	0.004	0.995	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.005	0.995	0.000
Q13 Congenital malformations of anterior segment of eye	0.005	0.995	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.004	0.995	0.000
Q04 Other congenital malformations of brain	0.005	0.995	0.000
Q15 Other congenital malformations of eye	0.005	0.995	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.005	0.995	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.004	0.995	0.000
Q50.3 Other congenital malformations of ovary	0.004	0.995	0.000
Q50.2 Congenital torsion of ovary	0.004	0.995	0.000
Q50.1 Developmental ovarian cyst	0.004	0.995	0.000
Q50.0 Congenital absence of ovary	0.004	0.995	0.000
C71.8 Overlapping lesion of brain	0.000	0.995	0.005
Q45.2 Congenital pancreatic cyst	0.004	0.995	0.000
Q45.1 Annular pancreas	0.004	0.995	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.004	0.995	0.000
Q38.6 Other congenital malformations of mouth	0.004	0.995	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.005	0.995	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.995	0.000
T48.4 Expectorants	0.004	0.995	0.000
T48.3 Antitussives	0.004	0.995	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.004	0.995	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.995	0.000
T48.0 Oxytocic drugs	0.004	0.995	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.005	0.995	0.000
Q69.9 Polydactyly, unspecified	0.004	0.995	0.000
Q69.2 Accessory toe(s)	0.004	0.995	0.000
Q69.1 Accessory thumb(s)	0.004	0.995	0.000
Q69.0 Accessory finger(s)	0.004	0.995	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.004	0.995	0.000
Q71.8 Other reduction defects of upper limb(s)	0.004	0.995	0.000
Q71.6 Lobster-claw hand	0.004	0.995	0.000
Q71.5 Longitudinal reduction defect of ulna	0.004	0.995	0.000
Q71.4 Longitudinal reduction defect of radius	0.004	0.995	0.000
Q71.3 Congenital absence of hand and finger(s)	0.004	0.995	0.000
Q71.2 Congenital absence of both forearm and hand	0.004	0.995	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.004	0.995	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.004	0.995	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.004	0.995	0.000
Q72.8 Other reduction defects of lower limb(s)	0.004	0.995	0.000
Q72.7 Split foot	0.004	0.995	0.000
Q72.6 Longitudinal reduction defect of fibula	0.004	0.995	0.000
Q72.5 Longitudinal reduction defect of tibia	0.004	0.995	0.000
Q72.4 Longitudinal reduction defect of femur	0.004	0.995	0.000
Q72.3 Congenital absence of foot and toe(s)	0.004	0.995	0.000
Q72.2 Congenital absence of both lower leg and foot	0.004	0.995	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.004	0.995	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.004	0.995	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.004	0.995	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.004	0.995	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.004	0.995	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.004	0.995	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.004	0.995	0.000
Q75.5 Oculomandibular dysostosis	0.004	0.995	0.000
Q75.4 Mandibulofacial dysostosis	0.004	0.995	0.000
Q75.3 Macrocephaly	0.004	0.995	0.000
Q75.2 Hypertelorism	0.004	0.995	0.000
Q75.1 Craniofacial dysostosis	0.004	0.995	0.000
Q75.0 Craniosynostosis	0.004	0.995	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.995	0.000
F01.1 Multi-infarct dementia	0.004	0.995	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.004	0.995	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.004	0.995	0.000
T45.8 Other primarily systemic and haematological agents	0.004	0.995	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.004	0.995	0.000
T45.6 Fibrinolysis-affecting drugs	0.004	0.995	0.000
T45.3 Enzymes, not elsewhere classified	0.004	0.995	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.004	0.995	0.000
Q01 Encephalocele	0.004	0.995	0.000
Q00 Anencephaly and similar malformations	0.004	0.995	0.000
Q02 Microcephaly	0.004	0.995	0.000
T71 Asphyxiation	0.004	0.995	0.000
Q27.4 Congenital phlebectasia	0.004	0.995	0.000
Q27.2 Other congenital malformations of renal artery	0.004	0.995	0.000
Q27.1 Congenital renal artery stenosis	0.004	0.995	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.004	0.995	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.004	0.995	0.000
Q83 Congenital malformations of breast	0.004	0.996	0.000
S02.10 Fracture of base of skull (closed)	0.004	0.996	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.004	0.996	0.000
T45.2 Vitamins, not elsewhere classified	0.004	0.996	0.000
Q06.2 Diastematomyelia	0.004	0.996	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.004	0.996	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.004	0.996	0.000
Q77.6 Chondroectodermal dysplasia	0.004	0.996	0.000
Q77.5 Diastrophic dysplasia	0.004	0.996	0.000
Q77.3 Chondrodysplasia punctata	0.004	0.996	0.000
Q77.2 Short rib syndrome	0.004	0.996	0.000
Q77.1 Thanatophoric short stature	0.004	0.996	0.000
Q77.0 Achondrogenesis	0.004	0.996	0.000
Q25 Congenital malformations of great arteries	0.004	0.996	0.000
Q54.4 Congenital chordee	0.004	0.996	0.000
Q54.3 Hypospadias, perineal	0.004	0.996	0.000
Q54.2 Hypospadias, penoscrotal	0.004	0.996	0.000
T70 Effects of air pressure and water pressure	0.004	0.996	0.000
Q80 Congenital ichthyosis	0.004	0.996	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.004	0.996	0.000
Q56.4 Indeterminate sex, unspecified	0.004	0.996	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.004	0.996	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.004	0.996	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.004	0.996	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.004	0.996	0.000
Q90 Down's syndrome	0.004	0.996	0.000
Q30.9 Congenital malformation of nose, unspecified	0.004	0.996	0.000
Q54.0 Hypospadias, balanic	0.004	0.996	0.000
Q76.1 Klippel-Feil syndrome	0.004	0.996	0.000
K05.3 Chronic periodontitis	0.000	0.996	0.004
Q68.5 Congenital bowing of long bones of leg, unspecified	0.004	0.996	0.000
Q68.4 Congenital bowing of tibia and fibula	0.004	0.996	0.000
Q68.3 Congenital bowing of femur	0.004	0.996	0.000
Q68.2 Congenital deformity of knee	0.004	0.996	0.000
Q68.1 Congenital deformity of hand	0.004	0.996	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.004	0.996	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.004	0.996	0.000
Q84 Other congenital malformations of integument	0.004	0.996	0.000
Q81 Epidermolysis bullosa	0.004	0.996	0.000
Q52.5 Fusion of labia	0.004	0.996	0.000
Q55.0 Absence and aplasia of testis	0.004	0.996	0.000
Q70.9 Syndactyly, unspecified	0.004	0.996	0.000
Q70.4 Polysyndactyly	0.004	0.996	0.000
Q70.2 Fused toes	0.004	0.996	0.000
Q70.1 Webbed fingers	0.004	0.996	0.000
Q70.0 Fused fingers	0.004	0.996	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
Q18 Other congenital malformations of face and neck	0.004	0.996	0.000
F01.8 Other vascular dementia	0.004	0.996	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.004	0.996	0.000
F01.2 Subcortical vascular dementia	0.004	0.996	0.000
F01.0 Vascular dementia of acute onset	0.004	0.996	0.000
Q23 Congenital malformations of aortic and mitral valves	0.004	0.996	0.000
T75 Effects of other external causes	0.004	0.996	0.000
Q11.1 Other anophthalmos	0.004	0.996	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.004	0.996	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.004	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.004	0.996	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.004	0.996	0.000
Q52.7 Other congenital malformations of vulva	0.004	0.996	0.000
Q52.6 Congenital malformation of clitoris	0.004	0.996	0.000
Q52.3 Imperforate hymen	0.004	0.996	0.000
Q52.2 Congenital rectovaginal fistula	0.004	0.996	0.000
Q52.0 Congenital absence of vagina	0.004	0.996	0.000
Q54.8 Other hypospadias	0.004	0.996	0.000
Q96.9 Turner's syndrome, unspecified	0.004	0.996	0.000
F02.0 Dementia in Pick's disease	0.004	0.996	0.000
Q14.1 Congenital malformation of retina	0.004	0.996	0.000
Q77.4 Achondroplasia	0.004	0.996	0.000
Q85.9 Phakomatosis, unspecified	0.004	0.996	0.000
Q35.9 Cleft palate, unspecified	0.004	0.996	0.000
Q17 Other congenital malformations of ear	0.004	0.996	0.000
C71.3 Parietal lobe	0.000	0.996	0.004
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.004	0.996	0.000
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
Q52.1 Doubling of vagina	0.004	0.996	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.004	0.996	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.004	0.996	0.000
Q55.5 Congenital absence and aplasia of penis	0.004	0.996	0.000
Q55.3 Atresia of vas deferens	0.004	0.996	0.000
Q55.1 Hypoplasia of testis and scrotum	0.004	0.996	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.004	0.996	0.000
Q30.3 Congenital perforated nasal septum	0.004	0.996	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.004	0.996	0.000
Q76.8 Other congenital malformations of bony thorax	0.004	0.996	0.000
Q76.7 Congenital malformation of sternum	0.004	0.996	0.000
Q76.6 Other congenital malformations of ribs	0.004	0.996	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations