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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9267649
log Bayes Factor = 133.096
Chromosome 6   position 31,824,828  (GRCh37) Explore rs9267649 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
G35-G37 Demyelinating diseases of the central nervous system
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.001 0.999
E14 Unspecified diabetes mellitus
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
G20 Parkinson's disease
0.998 0.002 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.002 0.998
G20-G26 Extrapyramidal and movement disorders
0.997 0.003 0.000
M06 Other rheumatoid arthritis
0.000 0.003 0.997
E16 Other disorders of pancreatic internal secretion
0.000 0.003 0.997
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.003 0.997
E83.1 Disorders of iron metabolism
0.997 0.003 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.005 0.995
I10-I15 Hypertensive diseases
0.000 0.006 0.994
G37 Other demyelinating diseases of central nervous system
0.992 0.008 0.000
I10 Essential (primary) hypertension
0.000 0.009 0.991
M05-M14 Inflammatory polyarthropathies
0.000 0.009 0.991
E14.3 With ophthalmic complications
0.000 0.012 0.988
E07 Other disorders of thyroid
0.000 0.012 0.988
I20-I25 Ischaemic heart diseases
0.000 0.012 0.988
J45 Asthma
0.000 0.013 0.987
Chapter IX Diseases of the circulatory system
0.000 0.014 0.986
E05.9 Thyrotoxicosis, unspecified
0.000 0.015 0.985
# Top node
0.001 0.016 0.984
J33.9 Nasal polyp, unspecified
0.000 0.016 0.984
J33 Nasal polyp
0.000 0.016 0.984
J40-J47 Chronic lower respiratory diseases
0.000 0.016 0.984
H36.0 Diabetic retinopathy
0.000 0.016 0.984
I22 Subsequent myocardial infarction
0.000 0.017 0.983
Chapter X Diseases of the respiratory system
0.000 0.017 0.983
G37.9 Demyelinating disease of central nervous system, unspecified
0.982 0.018 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.019 0.981
E07.9 Disorder of thyroid, unspecified
0.000 0.019 0.981
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.019 0.981
H36 Retinal disorders in diseases classified elsewhere
0.000 0.021 0.979
L40 Psoriasis
0.976 0.024 0.000
E14.9 Without complications
0.000 0.024 0.976
M05 Seropositive rheumatoid arthritis
0.000 0.024 0.976
I12 Hypertensive renal disease
0.000 0.024 0.976
H30-H36 Disorders of choroid and retina
0.000 0.025 0.975
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.028 0.972
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.030 0.970
J30-J39 Other diseases of upper respiratory tract
0.000 0.032 0.968
Chapter VII Diseases of the eye and adnexa
0.000 0.032 0.968
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.034 0.966
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.035 0.965
M45 Ankylosing spondylitis
0.000 0.035 0.965
M45-M49 Spondylopathies
0.000 0.037 0.963
I20 Angina pectoris
0.000 0.040 0.960
I12.9 Hypertensive renal disease without renal failure
0.000 0.044 0.956
I15 Secondary hypertension
0.000 0.052 0.948
H43-H45 Disorders of vitreous body and globe
0.000 0.053 0.947
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.053 0.947
J33.0 Polyp of nasal cavity
0.000 0.053 0.947
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.056 0.944
H43 Disorders of vitreous body
0.000 0.058 0.942
E10.5 With peripheral circulatory complications
0.000 0.059 0.941
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.061 0.939
L40.5 Arthropathic psoriasis
0.937 0.063 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.067 0.933
E11 Non-insulin-dependent diabetes mellitus
0.000 0.068 0.932
H43.8 Other disorders of vitreous body
0.000 0.068 0.932
E10.2 With renal complications
0.000 0.075 0.925
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.082 0.918
I20.9 Angina pectoris, unspecified
0.000 0.083 0.917
L40.0 Psoriasis vulgaris
0.915 0.085 0.000
I20.1 Angina pectoris with documented spasm
0.000 0.087 0.913
J44 Other chronic obstructive pulmonary disease
0.000 0.089 0.911
E83 Disorders of mineral metabolism
0.897 0.091 0.012
E10.8 With unspecified complications
0.000 0.096 0.904
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.100 0.900
J86 Pyothorax
0.000 0.103 0.897
J33.8 Other polyp of sinus
0.000 0.108 0.892
E11.9 Without complications
0.000 0.109 0.891
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.111 0.889
I15.1 Hypertension secondary to other renal disorders
0.000 0.113 0.887
I25 Chronic ischaemic heart disease
0.000 0.124 0.876
E70-E90 Metabolic disorders
0.005 0.129 0.867
E78.0 Pure hypercholesterolaemia
0.000 0.132 0.868
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.133 0.866
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.136 0.864
G37.8 Other specified demyelinating diseases of central nervous system
0.860 0.140 0.000
E13 Other specified diabetes mellitus
0.000 0.143 0.857
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.145 0.855
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.149 0.851
H35 Other retinal disorders
0.000 0.150 0.850
E06 Thyroiditis
0.000 0.155 0.845
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.159 0.841
H34 Retinal vascular occlusions
0.000 0.165 0.835
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.166 0.834
G40-G47 Episodic and paroxysmal disorders
0.834 0.166 0.000
M06.3 Rheumatoid nodule
0.000 0.166 0.834
E11.0 With coma
0.000 0.168 0.832
E83.3 Disorders of phosphorus metabolism
0.827 0.170 0.003
M65-M68 Disorders of synovium and tendon
0.000 0.172 0.828
J86.9 Pyothorax without fistula
0.000 0.176 0.824
G40 Epilepsy
0.824 0.176 0.000
G24 Dystonia
0.823 0.177 0.000
E10.6 With other specified complications
0.000 0.178 0.822
M06.4 Inflammatory polyarthropathy
0.000 0.179 0.821
I25.5 Ischaemic cardiomyopathy
0.000 0.183 0.817
J37 Chronic laryngitis and laryngotracheitis
0.000 0.186 0.814
H35.8 Other specified retinal disorders
0.000 0.189 0.811
J85 Abscess of lung and mediastinum
0.000 0.192 0.808
G30-G32 Other degenerative diseases of the nervous system
0.806 0.194 0.000
I15.9 Seconday hypertension, unspecified
0.000 0.200 0.800
I24 Other acute ischaemic heart diseases
0.000 0.200 0.800
E16.1 Other hypoglycaemia
0.000 0.202 0.798
J46 Status asthmaticus
0.000 0.204 0.796
E83.5 Disorders of calcium metabolism
0.795 0.205 0.001
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.207 0.793
I12.0 Hypertensive renal disease with renal failure
0.000 0.209 0.791
J42 Unspecified chronic bronchitis
0.000 0.214 0.786
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.785 0.215 0.000
H43.9 Disorder of vitreous body, unspecified
0.000 0.215 0.785
J86.0 Pyothorax with fistula
0.000 0.226 0.773
M65 Synovitis and tenosynovitis
0.000 0.227 0.773
M06.0 Seronegative rheumatoid arthritis
0.000 0.229 0.771
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.771 0.229 0.000
E03.8 Other specified hypothyroidism
0.000 0.230 0.770
E78.2 Mixed hyperlipidaemia
0.000 0.235 0.765
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.001 0.237 0.762
H43.2 Crystalline deposits in vitreous body
0.000 0.238 0.762
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.238 0.762
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.240 0.760
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.245 0.755
E13.9 Without complications
0.000 0.246 0.754
H31 Other disorders of choroid
0.000 0.246 0.754
I23 Certain current complications following acute myocardial infarction
0.000 0.247 0.753
G24.9 Dystonia, unspecified
0.749 0.251 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.251 0.749
H43.3 Other vitreous opacities
0.000 0.253 0.747
E11.5 With peripheral circulatory complications
0.000 0.254 0.746
J31.0 Chronic rhinitis
0.000 0.255 0.745
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.256 0.744
E14.6 With other specified complications
0.000 0.258 0.742
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.260 0.740
L40.3 Pustulosis palmaris et plantaris
0.736 0.264 0.000
E14.1 With ketoacidosis
0.000 0.268 0.732
E83.9 Disorder of mineral metabolism, unspecified
0.722 0.271 0.007
H35.4 Peripheral retinal degeneration
0.000 0.273 0.727
E06.3 Autoimmune thyroiditis
0.000 0.277 0.723
G80-G83 Cerebral palsy and other paralytic syndromes
0.720 0.280 0.000
K90 Intestinal malabsorption
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
G36 Other acute disseminated demyelination
0.717 0.283 0.000
E14.8 With unspecified complications
0.000 0.284 0.716
E14.7 With multiple complications
0.000 0.284 0.716
E14.5 With peripheral circulatory complications
0.000 0.284 0.716
E14.2 Withrenal complications
0.000 0.284 0.716
E14.0 With coma
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
G23 Other degenerative diseases of basal ganglia
0.715 0.285 0.000
G21 Secondary Parkinsonism
0.715 0.285 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.715 0.285 0.000
G22 Parkinsonism in diseases classified elsewhere
0.715 0.285 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.285 0.715
M06.2 Rheumatoid bursitis
0.000 0.285 0.715
M06.1 Adult-onset Still's disease
0.000 0.285 0.715
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.285 0.715
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.285 0.715
E16.4 Abnormal secretion of gastrin
0.000 0.285 0.715
E16.3 Increased secretion of glucagon
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
L40.1 Generalised pustular psoriasis
0.714 0.285 0.000
I13 Hypertensive heart and renal disease
0.000 0.287 0.713
I25.1 Atherosclerotic heart disease
0.000 0.288 0.712
G37.5 Concentric sclerosis [Balo]
0.711 0.289 0.000
G37.4 Subacute necrotising myelitis
0.711 0.289 0.000
G37.2 Central pontine myelinolysis
0.711 0.289 0.000
G37.1 Central demyelination of corpus callosum
0.711 0.289 0.000
G37.0 Diffuse sclerosis
0.711 0.289 0.000
E14.4 With neurological complications
0.000 0.289 0.711
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.290 0.710
M08 Juvenile arthritis
0.000 0.290 0.710
E07.1 Dyshormogenetic goitre
0.000 0.292 0.708
E07.0 Hypersecretion of calcitonin
0.000 0.292 0.708
J45.8 Mixed asthma
0.000 0.292 0.708
J45.1 Nonallergic asthma
0.000 0.292 0.708
I20.0 Unstable angina
0.000 0.292 0.708
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.294 0.706
Chapter XVI Certain conditions originating in the perinatal period
0.001 0.294 0.705
J33.1 Polypoid sinus degeneration
0.000 0.295 0.705
J41 Simple and mucopurulent chronic bronchitis
0.000 0.295 0.705
J37.0 Chronic laryngitis
0.000 0.297 0.703
E11.1 With ketoacidosis
0.000 0.298 0.702
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.298 0.702
H30 Chorioretinal inflammation
0.000 0.299 0.701
E78.1 Pure hyperglyceridaemia
0.000 0.299 0.701
L40.4 Guttate psoriasis
0.700 0.300 0.000
L40.2 Acrodermatitis continua
0.700 0.300 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.300 0.700
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.300 0.700
M05.2 Rheumatoid vasculitis
0.000 0.300 0.700
M05.1 Rheumatoid lung disease
0.000 0.300 0.700
M05.0 Felty's syndrome
0.000 0.300 0.700
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.301 0.699
M11 Other crystal arthropathies
0.000 0.301 0.699
G41 Status epilepticus
0.697 0.303 0.000
M49 Spondylopathies in diseases classified elsewhere
0.000 0.304 0.695
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.308 0.692
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.308 0.692
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.308 0.692
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.308 0.692
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.308 0.692
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.308 0.692
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.308 0.692
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.308 0.692
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.308 0.692
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.308 0.692
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.308 0.692
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.308 0.692
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.308 0.692
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.308 0.692
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.308 0.692
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.308 0.692
M14 Arthropathies in other diseases classified elsewhere
0.000 0.309 0.691
G46 Vascular syndromes of brain in cerebrovascular diseases
0.691 0.309 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.690 0.309 0.000
I25.2 Old myocardial infarction
0.000 0.310 0.690
I00-I02 Acute rheumatic fever
0.000 0.318 0.682
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.319 0.681
E40-E46 Malnutrition
0.000 0.320 0.680
I15.8 Other secondary hypertension
0.000 0.320 0.679
I15.2 Hypertension secondary to endocrine disorders
0.000 0.320 0.679
I15.0 Renovascular hypertension
0.000 0.320 0.679
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.321 0.679
J31.2 Chronic pharyngitis
0.000 0.324 0.676
H43.0 Vitreous prolapse
0.000 0.325 0.675
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.325 0.675
J85.2 Abscess of lung without pneumonia
0.000 0.325 0.675
H35.2 Other proliferative retinopathy
0.000 0.325 0.675
I11 Hypertensive heart disease
0.000 0.327 0.673
G40.5 Special epileptic syndromes
0.671 0.329 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.330 0.670
H34.2 Other retinal artery occlusions
0.000 0.331 0.669
E11.7 With multiple complications
0.000 0.332 0.668
E05.8 Other thyrotoxicosis
0.000 0.335 0.665
H40-H42 Glaucoma
0.000 0.335 0.665
G00-G09 Inflammatory diseases of the central nervous system
0.664 0.336 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.340 0.660
E11.6 With other specified complications
0.000 0.344 0.656
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.655 0.345 0.000
I22.8 Subsequent myocardial infarction of other sites
0.000 0.345 0.654
H34.1 Central retinal artery occlusion
0.000 0.346 0.654
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.346 0.654
E83.8 Other disorders of mineral metabolism
0.643 0.348 0.009
E83.2 Disorders of zinc metabolism
0.643 0.348 0.009
E83.0 Disorders of copper metabolism
0.643 0.348 0.009
M12 Other specific arthropathies
0.000 0.351 0.649
H34.8 Other retinal vascular occlusions
0.000 0.354 0.646
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.355 0.645
I25.4 Coronary artery aneurysm
0.000 0.356 0.644
E74 Other disorders of carbohydrate metabolism
0.003 0.356 0.640
K90.9 Intestinal malabsorption, unspecified
0.000 0.357 0.643
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.360 0.640
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.638 0.362 0.000
E79 Disorders of purine and pyrimidine metabolism
0.003 0.362 0.635
J85.1 Abscess of lung with pneumonia
0.000 0.363 0.637
H35.6 Retinal haemorrhage
0.000 0.366 0.634
H35.7 Separation of retinal layers
0.000 0.367 0.633
H31.0 Chorioretinal scars
0.000 0.369 0.631
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.629 0.371 0.000
L40.8 Other psoriasis
0.629 0.371 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.629 0.371 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.628 0.372 0.000
I25.6 Silent myocardial ischaemia
0.000 0.372 0.628
E06.9 Thyroiditis, unspecified
0.000 0.372 0.628
E07.8 Other specified disorders of thyroid
0.000 0.374 0.626
E77 Disorders of glycoprotein metabolism
0.003 0.375 0.621
E76 Disorders of glycosaminoglycan metabolism
0.003 0.375 0.621
E72 Other disorders of amino-acid metabolism
0.003 0.375 0.621
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.003 0.375 0.621
E70 Disorders of aromatic amino-acid metabolism
0.003 0.375 0.621
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.003 0.375 0.621
M80-M85 Disorders of bone density and structure
0.000 0.378 0.622
E78.3 Hyperchylomicronaemia
0.000 0.379 0.621
E11.2 With renal complications
0.000 0.380 0.619
E89.3 Postprocedural hypopituitarism
0.000 0.382 0.617
G25 Other extrapyramidal and movement disorders
0.617 0.383 0.000
E13.8 With unspecified complications
0.000 0.386 0.614
E13.7 With multiple complications
0.000 0.386 0.614
E13.6 With other specified complications
0.000 0.386 0.614
E13.5 With peripheral circulatory complications
0.000 0.386 0.614
E13.4 With neurological complications
0.000 0.386 0.614
E13.3 With ophthalmic complications
0.000 0.386 0.614
E13.2 With renal complications
0.000 0.386 0.614
E13.1 With ketoacidosis
0.000 0.386 0.614
E13.0 With coma
0.000 0.386 0.614
J31.1 Chronic nasopharyngitis
0.000 0.387 0.613
E11.8 With unspecified complications
0.000 0.387 0.613
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.388 0.612
G24.8 Other dystonia
0.611 0.389 0.000
H35.1 Retinopathy of prematurity
0.000 0.390 0.609
H35.5 Hereditary retinal dystrophy
0.000 0.391 0.609
G30 Alzheimer's disease
0.608 0.391 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.002 0.393 0.605
M15-M19 Arthrosis
0.000 0.394 0.606
E06.5 Other chronic thyroiditis
0.000 0.394 0.606
E06.4 Drug-induced thyroiditis
0.000 0.394 0.606
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.394 0.606
E06.1 Subacute thyroiditis
0.000 0.394 0.606
E06.0 Acute thyroiditis
0.000 0.394 0.606
H34.9 Retinal vascular occlusion, unspecified
0.000 0.398 0.602
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.601 0.398 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.399 0.601
E78.6 Lipoprotein deficiency
0.000 0.399 0.600
G41.0 Grand mal status epilepticus
0.599 0.400 0.000
H34.0 Transient retinal artery occlusion
0.000 0.401 0.599
E89.0 Postprocedural hypothyroidism
0.000 0.402 0.598
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.402 0.598
M06.38 Rheumatoid nodule (Other)
0.000 0.402 0.598
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.402 0.598
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.402 0.598
M06.33 Rheumatoid nodule (Forearm)
0.000 0.402 0.598
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.402 0.598
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.402 0.598
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.001 0.403 0.597
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.004 0.405 0.591
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.406 0.593
G40.8 Other epilepsy
0.592 0.408 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.408 0.592
M00-M03 Infectious arthropathies
0.000 0.409 0.591
G40.4 Other generalised epilepsy and epileptic syndromes
0.591 0.409 0.000
G24.4 Idiopathic orofacial dystonia
0.590 0.410 0.000
G24.2 Idiopathic nonfamilial dystonia
0.590 0.410 0.000
G24.1 Idiopathic familial dystonia
0.590 0.410 0.000
G24.0 Drug-induced dystonia
0.590 0.410 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.411 0.588
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.411 0.588
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.411 0.588
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.411 0.588
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.411 0.588
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.411 0.588
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.411 0.588
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.411 0.588
M18 Arthrosis of first carpometacarpal joint
0.000 0.412 0.588
H25-H28 Disorders of lens
0.000 0.413 0.587
E84 Cystic fibrosis
0.004 0.414 0.582
I23.8 Other current complications following acute myocardial infarction
0.000 0.415 0.585
E78.4 Other hyperlipidaemia
0.000 0.416 0.584
J37.1 Chronic laryngotracheitis
0.000 0.416 0.583
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.419 0.581
J85.3 Abscess of mediastinum
0.000 0.420 0.579
J85.0 Gangrene and necrosis of lung
0.000 0.420 0.579
G81 Hemiplegia
0.575 0.425 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.425 0.575
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.426 0.574
H31.1 Choroidal degeneration
0.000 0.428 0.572
M82 Osteoporosis in diseases classified elsewhere
0.000 0.430 0.570
M65.1 Other infective (teno)synovitis
0.000 0.431 0.569
G24.3 Spasmodic torticollis
0.568 0.432 0.000
M60-M63 Disorders of muscles
0.000 0.432 0.568
H43.1 Vitreous haemorrhage
0.000 0.434 0.566
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.437 0.563
G70-G73 Diseases of myoneural junction and muscle
0.561 0.439 0.000
G46.4 Cerebellar stroke syndrome
0.557 0.443 0.000
J60-J70 Lung diseases due to external agents
0.000 0.443 0.557
G31.9 Degenerative disease of nervous system, unspecified
0.555 0.445 0.000
M65.2 Calcific tendinitis
0.000 0.445 0.554
M65.0 Abscess of tendon sheath
0.000 0.445 0.554
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.447 0.553
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.447 0.553
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.447 0.553
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.447 0.553
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.447 0.553
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.447 0.553
G11 Hereditary ataxia
0.552 0.448 0.000
J95-J99 Other diseases of the respiratory system
0.000 0.448 0.552
H35.9 Retinal disorder, unspecified
0.000 0.451 0.549
G40.9 Epilepsy, unspecified
0.549 0.451 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.001 0.453 0.547
E89.8 Other postprocedural endocrine and metabolic disorders
0.001 0.453 0.547
E89.5 Postprocedural testicular hypofunction
0.001 0.453 0.547
E89.1 Postprocedural hypoinsulinaemia
0.001 0.453 0.547
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.454 0.546
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.454 0.546
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.454 0.546
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.454 0.546
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.454 0.546
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.454 0.546
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.454 0.546
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.454 0.546
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.454 0.546
I24.1 Dressler's syndrome
0.000 0.455 0.545
M15 Polyarthrosis
0.000 0.458 0.542
G46.7 Other lacunar syndromes
0.541 0.459 0.000
I25.3 Aneurysm of heart
0.000 0.459 0.541
H31.9 Disorder of choroid, unspecified
0.000 0.459 0.541
H31.4 Choroidal detachment
0.000 0.459 0.541
H31.3 Choroidal haemorrhage and rupture
0.000 0.459 0.541
H31.2 Hereditary choroidal dystrophy
0.000 0.459 0.541
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.460 0.540
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.460 0.540
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.460 0.540
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.460 0.540
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.460 0.540
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.460 0.540
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.460 0.540
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.000 0.463 0.537
M65.8 Other synovitis and tenosynovitis
0.000 0.465 0.535
M86-M90 Other osteopathies
0.000 0.466 0.534
H27 Other disorders of lens
0.000 0.467 0.533
M82.1 Osteoporosis in endocrine disorders
0.000 0.467 0.533
G00 Bacterial meningitis, not elsewhere classified
0.530 0.470 0.000
K90.8 Other intestinal malabsorption
0.000 0.473 0.527
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.475 0.525
H55-H59 Other disorders of eye and adnexa
0.000 0.477 0.523
M10 Gout
0.000 0.478 0.522
M11.2 Other chondrocalcinosis
0.000 0.478 0.521
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.481 0.519
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.518 0.482 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.002 0.483 0.515
K90.3 Pancreatic steatorrhoea
0.000 0.485 0.515
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.485 0.515
K90.1 Tropical sprue
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
G36.9 Acute disseminated demyelination, unspecified
0.514 0.486 0.000
G36.8 Other specified acute disseminated demyelination
0.514 0.486 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.514 0.486 0.000
G36.0 Neuromyelitis optica [Devic]
0.514 0.486 0.000
G21.9 Secondary Parkinsonism, unspecified
0.513 0.487 0.000
G21.8 Other secondary Parkinsonism
0.513 0.487 0.000
G21.4 Vascular parkinsonism
0.513 0.487 0.000
G21.3 Postencephalitic Parkinsonism
0.513 0.487 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.513 0.487 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.513 0.487 0.000
G21.0 Malignant neuroleptic syndrome
0.513 0.487 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.513 0.487 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.513 0.487 0.000
G23.3 Multiple system atrophy, cerebellar type
0.513 0.487 0.000
G23.2 Striatonigral degeneration
0.513 0.487 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.513 0.487 0.000
G23.0 Hallervorden-Spatz disease
0.513 0.487 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.487 0.513
M06.18 Adult-onset Still's disease (Other)
0.000 0.487 0.513
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.487 0.513
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.487 0.513
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.487 0.513
M06.14 Adult-onset Still's disease (Hand)
0.000 0.487 0.513
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.487 0.513
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.487 0.513
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.487 0.513
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.487 0.513
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.487 0.513
M06.28 Rheumatoid bursitis (Other)
0.000 0.487 0.513
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.487 0.513
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.487 0.513
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.487 0.513
M06.24 Rheumatoid bursitis (Hand)
0.000 0.487 0.513
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.487 0.513
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.487 0.513
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.487 0.513
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.487 0.513
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.487 0.513

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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