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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9267659
log Bayes Factor = 134.372
Chromosome 6   position 31,846,234  (GRCh37) Explore rs9267659 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.001 0.999
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.002 0.000
L40 Psoriasis
0.997 0.003 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.003 0.997
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.004 0.996
L40.5 Arthropathic psoriasis
0.996 0.004 0.000
E14 Unspecified diabetes mellitus
0.000 0.005 0.995
E11 Non-insulin-dependent diabetes mellitus
0.000 0.008 0.992
E05.9 Thyrotoxicosis, unspecified
0.000 0.009 0.991
E07 Other disorders of thyroid
0.000 0.011 0.989
E11.9 Without complications
0.000 0.016 0.984
E07.9 Disorder of thyroid, unspecified
0.000 0.017 0.983
G37 Other demyelinating diseases of central nervous system
0.982 0.018 0.000
E83.1 Disorders of iron metabolism
0.980 0.020 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.022 0.978
G20 Parkinson's disease
0.976 0.024 0.000
E14.3 With ophthalmic complications
0.000 0.025 0.975
G20-G26 Extrapyramidal and movement disorders
0.971 0.029 0.000
Chapter VI Diseases of the nervous system
0.968 0.032 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.963 0.037 0.000
E14.9 Without complications
0.000 0.047 0.953
E10.5 With peripheral circulatory complications
0.000 0.055 0.945
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.057 0.943
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.078 0.922
E06 Thyroiditis
0.000 0.079 0.921
E10.8 With unspecified complications
0.000 0.079 0.921
E10.2 With renal complications
0.000 0.085 0.915
E13 Other specified diabetes mellitus
0.000 0.094 0.906
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.096 0.904
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.098 0.902
E11.0 With coma
0.000 0.111 0.889
L40.0 Psoriasis vulgaris
0.876 0.124 0.000
E06.3 Autoimmune thyroiditis
0.000 0.136 0.864
G37.8 Other specified demyelinating diseases of central nervous system
0.858 0.142 0.000
E10.0 With coma
0.000 0.150 0.850
E11.5 With peripheral circulatory complications
0.000 0.152 0.848
E13.9 Without complications
0.000 0.161 0.839
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.163 0.837
E16.1 Other hypoglycaemia
0.000 0.179 0.821
E10.6 With other specified complications
0.000 0.180 0.820
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.183 0.817
E11.2 With renal complications
0.000 0.187 0.813
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.197 0.803
M06 Other rheumatoid arthritis
0.000 0.200 0.800
E78.0 Pure hypercholesterolaemia
0.000 0.202 0.798
E03.8 Other specified hypothyroidism
0.000 0.204 0.796
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.789 0.211 0.000
E70-E90 Metabolic disorders
0.008 0.212 0.780
G24 Dystonia
0.787 0.213 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.215 0.785
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.225 0.775
L40.3 Pustulosis palmaris et plantaris
0.755 0.245 0.000
L40.1 Generalised pustular psoriasis
0.754 0.246 0.000
G62 Other polyneuropathies
0.749 0.251 0.000
E83 Disorders of mineral metabolism
0.694 0.263 0.043
E14.6 With other specified complications
0.000 0.271 0.729
E14.4 With neurological complications
0.000 0.277 0.723
G62.9 Polyneuropathy, unspecified
0.718 0.282 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
G36 Other acute disseminated demyelination
0.715 0.285 0.000
L40.4 Guttate psoriasis
0.715 0.285 0.000
L40.2 Acrodermatitis continua
0.715 0.285 0.000
E05.5 Thyroid crisis or storm
0.000 0.286 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.286 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.286 0.714
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.286 0.714
E14.8 With unspecified complications
0.000 0.286 0.714
E14.7 With multiple complications
0.000 0.286 0.714
E14.2 Withrenal complications
0.000 0.286 0.714
E14.0 With coma
0.000 0.286 0.714
E11.6 With other specified complications
0.000 0.287 0.713
E11.7 With multiple complications
0.000 0.289 0.711
E07.1 Dyshormogenetic goitre
0.000 0.291 0.709
E07.0 Hypersecretion of calcitonin
0.000 0.291 0.709
E14.1 With ketoacidosis
0.000 0.294 0.706
G37.5 Concentric sclerosis [Balo]
0.704 0.296 0.000
G37.4 Subacute necrotising myelitis
0.704 0.296 0.000
G37.2 Central pontine myelinolysis
0.704 0.296 0.000
G37.1 Central demyelination of corpus callosum
0.704 0.296 0.000
G37.0 Diffuse sclerosis
0.704 0.296 0.000
G24.9 Dystonia, unspecified
0.696 0.304 0.000
G23 Other degenerative diseases of basal ganglia
0.696 0.304 0.000
G21 Secondary Parkinsonism
0.696 0.304 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.696 0.304 0.000
G22 Parkinsonism in diseases classified elsewhere
0.696 0.304 0.000
G30-G32 Other degenerative diseases of the nervous system
0.696 0.304 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.307 0.693
E40-E46 Malnutrition
0.000 0.311 0.689
G00-G09 Inflammatory diseases of the central nervous system
0.688 0.312 0.000
E11.1 With ketoacidosis
0.000 0.313 0.687
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.001 0.325 0.673
E78.1 Pure hyperglyceridaemia
0.000 0.328 0.672
G40-G47 Episodic and paroxysmal disorders
0.671 0.329 0.000
E14.5 With peripheral circulatory complications
0.000 0.334 0.666
E06.9 Thyroiditis, unspecified
0.000 0.334 0.665
E06.5 Other chronic thyroiditis
0.000 0.339 0.661
E06.4 Drug-induced thyroiditis
0.000 0.339 0.661
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.339 0.661
E06.1 Subacute thyroiditis
0.000 0.339 0.661
E06.0 Acute thyroiditis
0.000 0.339 0.661
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.343 0.657
E11.8 With unspecified complications
0.000 0.344 0.656
E05.8 Other thyrotoxicosis
0.000 0.347 0.653
E78.2 Mixed hyperlipidaemia
0.000 0.347 0.653
G40 Epilepsy
0.653 0.347 0.000
M05 Seropositive rheumatoid arthritis
0.001 0.349 0.651
E13.8 With unspecified complications
0.000 0.350 0.650
E13.7 With multiple complications
0.000 0.350 0.650
E13.6 With other specified complications
0.000 0.350 0.650
E13.5 With peripheral circulatory complications
0.000 0.350 0.650
E13.4 With neurological complications
0.000 0.350 0.650
E13.3 With ophthalmic complications
0.000 0.350 0.650
E13.2 With renal complications
0.000 0.350 0.650
E13.1 With ketoacidosis
0.000 0.350 0.650
E13.0 With coma
0.000 0.350 0.650
M05-M14 Inflammatory polyarthropathies
0.001 0.351 0.648
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.359 0.641
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.640 0.360 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.362 0.638
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.364 0.636
L40.8 Other psoriasis
0.634 0.366 0.000
E07.8 Other specified disorders of thyroid
0.000 0.374 0.626
M06.4 Inflammatory polyarthropathy
0.000 0.375 0.625
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.616 0.384 0.000
E83.3 Disorders of phosphorus metabolism
0.603 0.385 0.013
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.614 0.386 0.000
G62.8 Other specified polyneuropathies
0.601 0.399 0.000
M06.3 Rheumatoid nodule
0.000 0.404 0.596
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.589 0.411 0.000
K90 Intestinal malabsorption
0.000 0.413 0.587
G24.3 Spasmodic torticollis
0.577 0.423 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.548 0.425 0.027
M06.8 Other specified rheumatoid arthritis
0.000 0.426 0.573
M06.2 Rheumatoid bursitis
0.000 0.426 0.573
M06.1 Adult-onset Still's disease
0.000 0.426 0.573
E78.8 Other disorders of lipoprotein metabolism
0.000 0.430 0.570
G46 Vascular syndromes of brain in cerebrovascular diseases
0.569 0.431 0.000
G64 Other disorders of peripheral nervous system
0.565 0.434 0.000
E77 Disorders of glycoprotein metabolism
0.006 0.435 0.559
E76 Disorders of glycosaminoglycan metabolism
0.006 0.435 0.559
E72 Other disorders of amino-acid metabolism
0.006 0.435 0.559
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.006 0.435 0.559
E70 Disorders of aromatic amino-acid metabolism
0.006 0.435 0.559
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.006 0.435 0.559
G24.4 Idiopathic orofacial dystonia
0.564 0.436 0.000
G24.2 Idiopathic nonfamilial dystonia
0.564 0.436 0.000
G24.1 Idiopathic familial dystonia
0.564 0.436 0.000
G24.0 Drug-induced dystonia
0.564 0.436 0.000
E78.3 Hyperchylomicronaemia
0.000 0.437 0.563
E83.5 Disorders of calcium metabolism
0.559 0.439 0.002
E74 Other disorders of carbohydrate metabolism
0.006 0.439 0.555
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.560 0.439 0.000
E84 Cystic fibrosis
0.006 0.440 0.554
E89.3 Postprocedural hypopituitarism
0.001 0.445 0.555
G62.1 Alcoholic polyneuropathy
0.554 0.446 0.000
G25 Other extrapyramidal and movement disorders
0.553 0.447 0.000
E78.6 Lipoprotein deficiency
0.000 0.449 0.550
E89.0 Postprocedural hypothyroidism
0.000 0.452 0.548
G40.7 Petit mal, unspecified, without grand mal seizures
0.548 0.452 0.000
E79 Disorders of purine and pyrimidine metabolism
0.006 0.454 0.540
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.545 0.455 0.000
G60 Hereditary and idiopathic neuropathy
0.539 0.461 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.462 0.538
G62.2 Polyneuropathy due to other toxic agents
0.537 0.463 0.000
G24.8 Other dystonia
0.537 0.463 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.534 0.466 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.467 0.533
G41 Status epilepticus
0.531 0.469 0.000
E83.8 Other disorders of mineral metabolism
0.497 0.472 0.031
E83.2 Disorders of zinc metabolism
0.497 0.472 0.031
E83.0 Disorders of copper metabolism
0.497 0.472 0.031
G04 Encephalitis, myelitis and encephalomyelitis
0.526 0.474 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.006 0.479 0.515
G31.9 Degenerative disease of nervous system, unspecified
0.521 0.479 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.520 0.480 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.001 0.481 0.518
G00 Bacterial meningitis, not elsewhere classified
0.516 0.483 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
G36.9 Acute disseminated demyelination, unspecified
0.513 0.487 0.000
G36.8 Other specified acute disseminated demyelination
0.513 0.487 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.513 0.487 0.000
G36.0 Neuromyelitis optica [Devic]
0.513 0.487 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.488 0.512
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.490 0.510
E78.4 Other hyperlipidaemia
0.000 0.490 0.509
G80-G83 Cerebral palsy and other paralytic syndromes
0.507 0.493 0.000
G70-G73 Diseases of myoneural junction and muscle
0.501 0.498 0.000
G21.9 Secondary Parkinsonism, unspecified
0.499 0.501 0.000
G21.8 Other secondary Parkinsonism
0.499 0.501 0.000
G21.4 Vascular parkinsonism
0.499 0.501 0.000
G21.3 Postencephalitic Parkinsonism
0.499 0.501 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.499 0.501 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.499 0.501 0.000
G21.0 Malignant neuroleptic syndrome
0.499 0.501 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.499 0.501 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.499 0.501 0.000
G23.3 Multiple system atrophy, cerebellar type
0.499 0.501 0.000
G23.2 Striatonigral degeneration
0.499 0.501 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.499 0.501 0.000
G23.0 Hallervorden-Spatz disease
0.499 0.501 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.498 0.502 0.000
E89.2 Postprocedural hypoparathyroidism
0.001 0.503 0.496
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.506 0.494
E45 Retarded development following protein-energy malnutrition
0.000 0.506 0.494
E43 Unspecified severe protein-energy malnutrition
0.000 0.506 0.494
E42 Marasmic kwashiorkor
0.000 0.506 0.494
E41 Nutritional marasmus
0.000 0.506 0.494
E40 Kwashiorkor
0.000 0.506 0.494
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.493 0.507 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.508 0.491
G09 Sequelae of inflammatory diseases of central nervous system
0.490 0.509 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.511 0.489
E65-E68 Obesity and other hyperalimentation
0.000 0.512 0.488
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.001 0.516 0.483
E89.8 Other postprocedural endocrine and metabolic disorders
0.001 0.516 0.483
E89.5 Postprocedural testicular hypofunction
0.001 0.516 0.483
E89.1 Postprocedural hypoinsulinaemia
0.001 0.516 0.483
G24.5 Blepharospasm
0.482 0.518 0.000
G40.5 Special epileptic syndromes
0.480 0.520 0.000
G46.4 Cerebellar stroke syndrome
0.479 0.521 0.000
E11.3 With ophthalmic complications
0.000 0.524 0.476
I10 Essential (primary) hypertension
0.000 0.529 0.471
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.529 0.471
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.529 0.471
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.529 0.471
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.529 0.471
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.529 0.471
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.529 0.471
G40.4 Other generalised epilepsy and epileptic syndromes
0.468 0.532 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.467 0.533 0.000
M05.8 Other seropositive rheumatoid arthritis
0.001 0.533 0.467
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.001 0.533 0.467
M05.2 Rheumatoid vasculitis
0.001 0.533 0.467
M05.1 Rheumatoid lung disease
0.001 0.533 0.467
M05.0 Felty's syndrome
0.001 0.533 0.467
E46 Unspecified protein-energy malnutrition
0.000 0.534 0.466
M09 Juvenile arthritis in diseases classified elsewhere
0.001 0.535 0.464
M08 Juvenile arthritis
0.001 0.535 0.464
G03 Meningitis due to other and unspecified causes
0.465 0.535 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.464 0.535 0.000
G90-G99 Other disorders of the nervous system
0.464 0.536 0.000
G41.0 Grand mal status epilepticus
0.460 0.540 0.000
K90.8 Other intestinal malabsorption
0.000 0.545 0.455
E80 Disorders of porphyrin and bilirubin metabolism
0.005 0.551 0.444
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.552 0.448
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.552 0.448
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.552 0.448
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.552 0.448
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.552 0.448
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.552 0.448
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.552 0.448
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.552 0.448
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.443 0.556 0.000
G62.0 Drug-induced polyneuropathy
0.443 0.557 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.442 0.558 0.000
G40.8 Other epilepsy
0.441 0.559 0.000
G46.7 Other lacunar syndromes
0.440 0.560 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.440 0.560 0.000
G25.1 Drug-induced tremor
0.439 0.561 0.000
J33.9 Nasal polyp, unspecified
0.000 0.564 0.436
G01 Meningitis in bacterial diseases classified elsewhere
0.435 0.565 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.565 0.435
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.435 0.565 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.434 0.566 0.000
M11 Other crystal arthropathies
0.001 0.566 0.433
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.567 0.433
G11 Hereditary ataxia
0.432 0.568 0.000
G06.0 Intracranial abscess and granuloma
0.430 0.570 0.000
E89.4 Postprocedural ovarian failure
0.001 0.571 0.428
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.572 0.427
M06.38 Rheumatoid nodule (Other)
0.000 0.572 0.427
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.572 0.427
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.572 0.427
M06.33 Rheumatoid nodule (Forearm)
0.000 0.572 0.427
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.572 0.427
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.572 0.427
E74.3 Other disorders of intestinal carbohydrate absorption
0.003 0.572 0.424
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.575 0.425
G44 Other headache syndromes
0.425 0.575 0.000
G10 Huntington's disease
0.423 0.577 0.000
G60.8 Other hereditary and idiopathic neuropathies
0.423 0.577 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.422 0.577 0.000
E73 Lactose intolerance
0.008 0.578 0.415
K90.3 Pancreatic steatorrhoea
0.000 0.579 0.421
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.579 0.421
K90.1 Tropical sprue
0.000 0.579 0.421
I10-I15 Hypertensive diseases
0.000 0.581 0.419
G40.9 Epilepsy, unspecified
0.419 0.581 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.418 0.582 0.000
G96 Other disorders of central nervous system
0.415 0.585 0.000
G70 Myasthenia gravis and other myoneural disorders
0.414 0.585 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.588 0.412
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.589 0.411
M06.18 Adult-onset Still's disease (Other)
0.000 0.589 0.411
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.589 0.411
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.589 0.411
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.589 0.411
M06.14 Adult-onset Still's disease (Hand)
0.000 0.589 0.411
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.589 0.411
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.589 0.411
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.589 0.411
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.589 0.411
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.589 0.411
M06.28 Rheumatoid bursitis (Other)
0.000 0.589 0.411
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.589 0.411
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.589 0.411
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.589 0.411
M06.24 Rheumatoid bursitis (Hand)
0.000 0.589 0.411
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.589 0.411
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.589 0.411
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.589 0.411
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.589 0.411
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.589 0.411
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.589 0.411
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.589 0.411
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.589 0.411
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.589 0.411
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.589 0.411
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.589 0.411
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.589 0.411
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.589 0.411
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.589 0.411
J33 Nasal polyp
0.000 0.591 0.409
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.408 0.592 0.000
G46.6 Pure sensory lacunar syndrome
0.408 0.592 0.000
G46.5 Pure motor lacunar syndrome
0.408 0.592 0.000
G46.3 Brain stem stroke syndrome
0.408 0.592 0.000
G46.2 Posterior cerebral artery syndrome
0.408 0.592 0.000
G46.1 Anterior cerebral artery syndrome
0.408 0.592 0.000
G46.0 Middle cerebral artery syndrome
0.408 0.592 0.000
G06.2 Extradural and subdural abscess, unspecified
0.405 0.594 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.004 0.595 0.401
E70.8 Other disorders of aromatic amino-acid metabolism
0.004 0.595 0.401
E70.3 Albinism
0.004 0.595 0.401
E70.2 Disorders of tyrosine metabolism
0.004 0.595 0.401
E70.1 Other hyperphenylalaninaemias
0.004 0.595 0.401
E70.0 Classical phenylketonuria
0.004 0.595 0.401
E71.3 Disorders of fatty-acid metabolism
0.004 0.595 0.401
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.004 0.595 0.401
E71.1 Other disorders of branched-chain amino-acid metabolism
0.004 0.595 0.401
E71.0 Maple-syrup-urine disease
0.004 0.595 0.401
E72.9 Disorder of amino-acid metabolism, unspecified
0.004 0.595 0.401
E72.8 Other specified disorders of amino-acid metabolism
0.004 0.595 0.401
E72.5 Disorders of glycine metabolism
0.004 0.595 0.401
E72.4 Disorders of ornithine metabolism
0.004 0.595 0.401
E72.3 Disorders of lysine and hydroxylysine metabolism
0.004 0.595 0.401
E72.2 Disorders of urea cycle metabolism
0.004 0.595 0.401
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.004 0.595 0.401
E72.0 Disorders of amino-acid transport
0.004 0.595 0.401
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.004 0.595 0.401
E76.8 Other disorders of glucosaminoglycan metabolism
0.004 0.595 0.401
E76.3 Mucopolysaccharidosis, unspecified
0.004 0.595 0.401
E76.2 Other mucopolysaccharidoses
0.004 0.595 0.401
E76.1 Mucopolysaccharidosis, type II
0.004 0.595 0.401
E76.0 Mucopolysaccharidosis, type I
0.004 0.595 0.401
E77.9 Disorder of glycoprotein metabolism, unspecified
0.004 0.595 0.401
E77.8 Other disorders of glycoprotein metabolism
0.004 0.595 0.401
E77.1 Defects in glycoprotein degradation
0.004 0.595 0.401
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.004 0.595 0.401
G14 Postpolio syndrome
0.404 0.596 0.000
I12 Hypertensive renal disease
0.000 0.597 0.403
E74.9 Disorder of carbohydrate metabolism, unspecified
0.004 0.598 0.398
E74.8 Other specified disorders of carbohydrate metabolism
0.004 0.598 0.398
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.004 0.598 0.398
E74.2 Disorders of galactose metabolism
0.004 0.598 0.398
E74.1 Disorders of fructose metabolism
0.004 0.598 0.398
G31.1 Senile degeneration of brain, not elsewhere classified
0.402 0.598 0.000
G25.5 Other chorea
0.402 0.598 0.000
E84.8 Cystic fibrosis with other manifestations
0.004 0.599 0.397
E84.1 Cystic fibrosis with intestinal manifestations
0.004 0.599 0.397
E84.0 Cystic fibrosis with pulmonary manifestations
0.004 0.599 0.397
G31.2 Degeneration of nervous system due to alcohol
0.399 0.601 0.000
G00.9 Bacterial meningitis, unspecified
0.399 0.601 0.000
M12 Other specific arthropathies
0.001 0.603 0.396
G25.6 Drug-induced tics and other tics of organic origin
0.397 0.603 0.000
G25.4 Drug-induced chorea
0.397 0.603 0.000
E84.9 Cystic fibrosis, unspecified
0.004 0.604 0.391
E23 Hypofunction and other disorders of pituitary gland
0.000 0.606 0.394
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.004 0.608 0.387
E79.8 Other disorders of purine and pyrimidine metabolism
0.004 0.608 0.387
E79.1 Lesch-Nyhan syndrome
0.004 0.608 0.387
G96.0 Cerebrospinal fluid leak
0.392 0.608 0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.391 0.609 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.391 0.609 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.391 0.609 0.000
M14 Arthropathies in other diseases classified elsewhere
0.001 0.610 0.389
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.386 0.613 0.000
G60.3 Idiopathic progressive neuropathy
0.386 0.613 0.000
G60.2 Neuropathy in association with hereditary ataxia
0.386 0.613 0.000
G60.1 Refsum's disease
0.386 0.613 0.000
J33.8 Other polyp of sinus
0.000 0.614 0.386
E29 Testicular dysfunction
0.000 0.614 0.386
G25.2 Other specified forms of tremor
0.384 0.616 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.384 0.616 0.000
I12.9 Hypertensive renal disease without renal failure
0.000 0.617 0.383
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.383 0.617 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.617 0.382
G98 Other disorders of nervous system, not elsewhere classified
0.382 0.618 0.000
G41.8 Other status epilepticus
0.380 0.619 0.000
G41.2 Complex partial status epilepticus
0.380 0.619 0.000
G41.1 Petit mal status epilepticus
0.380 0.619 0.000
G61 Inflammatory polyneuropathy
0.378 0.621 0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.377 0.623 0.000
G04.1 Tropical spastic paraplegia
0.377 0.623 0.000
G04.0 Acute disseminated encephalitis
0.377 0.623 0.000
E85 Amyloidosis
0.007 0.623 0.370
J33.0 Polyp of nasal cavity
0.000 0.624 0.376
E75.6 Lipid storage disorder, unspecified
0.005 0.626 0.369
E75.4 Neuronal ceroid lipofuscinosis
0.005 0.626 0.369
E75.3 Sphingolipidosis, unspecified
0.005 0.626 0.369
E75.2 Other sphingolipidosis
0.005 0.626 0.369
E75.1 Other gangliosidosis
0.005 0.626 0.369
E75.0 GM2 gangliosidosis
0.005 0.626 0.369
I15 Secondary hypertension
0.000 0.626 0.374
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.004 0.627 0.368
G00.8 Other bacterial meningitis
0.370 0.629 0.000
G00.3 Staphylococcal meningitis
0.370 0.629 0.000
G00.2 Streptococcal meningitis
0.370 0.629 0.000
G00.0 Haemophilus meningitis
0.370 0.629 0.000
E74.0 Glycogen storage disease
0.004 0.634 0.361
G80 Infantile cerebral palsy
0.365 0.635 0.000
G00.1 Pneumococcal meningitis
0.364 0.636 0.000
G31.0 Circumscribed brain atrophy
0.364 0.636 0.000
G93 Other disorders of brain
0.361 0.639 0.000
E65 Localised adiposity
0.000 0.640 0.360
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.359 0.640 0.000
G25.3 Myoclonus
0.358 0.642 0.000
M07 Psoriatic and enteropathic arthropathies
0.076 0.642 0.282
E44.1 Mild protein-energy malnutrition
0.000 0.646 0.354
E44.0 Moderate protein-energy malnutrition
0.000 0.646 0.354
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.647 0.352
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.647 0.352
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.647 0.352
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.647 0.352
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.647 0.352
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.647 0.352
G70.0 Myasthenia gravis
0.352 0.648 0.000
E67 Other hyperalimentation
0.000 0.650 0.350
E68 Sequelae of hyperalimentation
0.000 0.650 0.350
E29.1 Testicular hypofunction
0.000 0.650 0.350
G30 Alzheimer's disease
0.350 0.650 0.000
E23.2 Diabetes insipidus
0.000 0.656 0.344
E88 Other metabolic disorders
0.007 0.657 0.336
G11.4 Hereditary spastic paraplegia
0.342 0.658 0.000
G83 Other paralytic syndromes
0.341 0.659 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.659 0.341
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.338 0.661 0.000
M05.09 Felty's syndrome (Site unspecified)
0.001 0.665 0.335
M05.08 Felty's syndrome (Other)
0.001 0.665 0.335
M05.07 Felty's syndrome (Ankle and foot)
0.001 0.665 0.335
M05.06 Felty's syndrome (Lower leg)
0.001 0.665 0.335

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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