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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9269878
log Bayes Factor = 212.626
Chromosome 6   position 32,550,876  (GRCh37) Explore rs9269878 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
Chapter VII Diseases of the eye and adnexa
0.000 0.001 0.999
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.001 0.000
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
G37 Other demyelinating diseases of central nervous system
0.998 0.002 0.000
J33.9 Nasal polyp, unspecified
0.000 0.002 0.998
E14.9 Without complications
0.000 0.002 0.998
J44 Other chronic obstructive pulmonary disease
0.000 0.002 0.998
E83.1 Disorders of iron metabolism
0.998 0.002 0.000
J33 Nasal polyp
0.000 0.002 0.998
G37.9 Demyelinating disease of central nervous system, unspecified
0.998 0.002 0.000
K70-K77 Diseases of liver
0.000 0.002 0.998
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.004 0.996
E14.3 With ophthalmic complications
0.000 0.004 0.996
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.004 0.996
K51.3 Ulcerative (chronic) rectosigmoiditis
0.995 0.005 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.007 0.993
K82 Other diseases of gallbladder
0.000 0.007 0.993
K50-K52 Noninfective enteritis and colitis
0.002 0.008 0.990
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.009 0.991
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.010 0.990
K82.8 Other specified diseases of gallbladder
0.000 0.011 0.989
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.012 0.988
E70-E90 Metabolic disorders
0.000 0.012 0.988
K74 Fibrosis and cirrhosis of liver
0.000 0.013 0.987
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.016 0.984
J30-J39 Other diseases of upper respiratory tract
0.000 0.016 0.984
J33.8 Other polyp of sinus
0.000 0.017 0.983
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.017 0.983
H43-H45 Disorders of vitreous body and globe
0.000 0.018 0.982
E10.5 With peripheral circulatory complications
0.000 0.020 0.980
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.021 0.979
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.022 0.978
Chapter IX Diseases of the circulatory system
0.000 0.023 0.977
I20-I25 Ischaemic heart diseases
0.000 0.025 0.975
H43 Disorders of vitreous body
0.000 0.026 0.974
E11.3 With ophthalmic complications
0.000 0.026 0.974
E05.9 Thyrotoxicosis, unspecified
0.000 0.027 0.973
K55-K64 Other diseases of intestines
0.000 0.027 0.973
I10-I15 Hypertensive diseases
0.000 0.028 0.972
H40-H42 Glaucoma
0.000 0.028 0.972
K74.3 Primary biliary cirrhosis
0.000 0.029 0.971
K50 Crohn's disease [regional enteritis]
0.000 0.034 0.966
E11.1 With ketoacidosis
0.000 0.034 0.966
K51.8 Other ulcerative colitis
0.964 0.036 0.000
E06 Thyroiditis
0.000 0.036 0.964
K75 Other inflammatory liver diseases
0.000 0.042 0.958
K60 Fissure and fistula of anal and rectal regions
0.000 0.042 0.958
L40-L45 Papulosquamous disorders
0.000 0.046 0.954
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.046 0.954
I22 Subsequent myocardial infarction
0.000 0.046 0.954
L43 Lichen planus
0.000 0.046 0.954
L43.9 Lichen planus, unspecified
0.000 0.047 0.953
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.047 0.953
H40 Glaucoma
0.000 0.048 0.952
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.049 0.951
J43 Emphysema
0.000 0.051 0.949
L40 Psoriasis
0.000 0.052 0.948
J46 Status asthmaticus
0.000 0.053 0.947
H43.3 Other vitreous opacities
0.000 0.054 0.946
H40.9 Glaucoma, unspecified
0.000 0.055 0.945
I10 Essential (primary) hypertension
0.000 0.057 0.943
E06.3 Autoimmune thyroiditis
0.000 0.060 0.940
E10.2 With renal complications
0.000 0.060 0.940
L40.5 Arthropathic psoriasis
0.000 0.062 0.938
I20 Angina pectoris
0.000 0.065 0.935
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.069 0.931
K75.4 Autoimmune hepatitis
0.000 0.071 0.929
M06.0 Seronegative rheumatoid arthritis
0.000 0.073 0.927
J86 Pyothorax
0.000 0.073 0.927
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.074 0.925
K60.2 Anal fissure, unspecified
0.000 0.076 0.924
K52 Other non-infective gastro-enteritis and colitis
0.000 0.077 0.923
K63 Other diseases of intestine
0.000 0.077 0.923
K86 Other diseases of pancreas
0.000 0.079 0.921
K72 Hepatic failure, not elsewhere classified
0.000 0.079 0.921
H34 Retinal vascular occlusions
0.000 0.081 0.919
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.084 0.916
K58 Irritable bowel syndrome
0.000 0.086 0.914
E11.5 With peripheral circulatory complications
0.000 0.086 0.914
J43.9 Emphysema, unspecified
0.000 0.091 0.909
E07 Other disorders of thyroid
0.000 0.093 0.907
K60.0 Acute anal fissure
0.000 0.096 0.904
M70-M79 Other soft tissue disorders
0.000 0.097 0.903
H43.8 Other disorders of vitreous body
0.000 0.097 0.903
K63.9 Disease of intestine, unspecified
0.000 0.097 0.903
K50.1 Crohn's disease of large intestine
0.000 0.098 0.902
I12 Hypertensive renal disease
0.000 0.101 0.899
E03.8 Other specified hypothyroidism
0.000 0.101 0.899
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.101 0.899
K82.1 Hydrops of gallbladder
0.000 0.108 0.892
K51.2 Ulcerative (chronic) proctitis
0.892 0.108 0.000
M65-M68 Disorders of synovium and tendon
0.000 0.114 0.886
M07 Psoriatic and enteropathic arthropathies
0.000 0.114 0.886
E11.2 With renal complications
0.000 0.115 0.885
E13 Other specified diabetes mellitus
0.000 0.118 0.882
J86.9 Pyothorax without fistula
0.000 0.118 0.882
E11.6 With other specified complications
0.000 0.121 0.879
I24 Other acute ischaemic heart diseases
0.000 0.125 0.875
K63.3 Ulcer of intestine
0.000 0.128 0.872
H25-H28 Disorders of lens
0.000 0.132 0.868
K81 Cholecystitis
0.000 0.134 0.866
I20.9 Angina pectoris, unspecified
0.000 0.134 0.866
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.134 0.866
K50.8 Other Crohn's disease
0.000 0.136 0.864
H40.1 Primary open-angle glaucoma
0.000 0.140 0.860
I20.1 Angina pectoris with documented spasm
0.000 0.140 0.860
M06.3 Rheumatoid nodule
0.000 0.146 0.853
M77 Other enthesopathies
0.000 0.147 0.853
E07.9 Disorder of thyroid, unspecified
0.000 0.147 0.853
E78.5 Hyperlipidaemia, unspecified
0.000 0.147 0.853
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.153 0.847
K74.5 Biliary cirrhosis, unspecified
0.000 0.154 0.846
K86.2 Cyst of pancreas
0.000 0.156 0.844
L40.9 Psoriasis, unspecified
0.000 0.156 0.844
K52.1 Toxic gastro-enteritis and colitis
0.000 0.156 0.844
M77.1 Lateral epicondylitis
0.000 0.157 0.843
J33.0 Polyp of nasal cavity
0.000 0.159 0.841
J95-J99 Other diseases of the respiratory system
0.000 0.162 0.838
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.162 0.838
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.163 0.837
K51.4 Pseudopolyposis of colon
0.836 0.164 0.000
K73 Chronic hepatitis, not elsewhere classified
0.000 0.164 0.836
K60.5 Anorectal fistula
0.000 0.165 0.835
K72.9 Hepatic failure, unspecified
0.000 0.165 0.835
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.166 0.834
M65 Synovitis and tenosynovitis
0.000 0.169 0.831
K81.1 Chronic cholecystitis
0.000 0.170 0.830
I15 Secondary hypertension
0.000 0.172 0.828
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.174 0.826
G37.8 Other specified demyelinating diseases of central nervous system
0.822 0.178 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.179 0.821
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.180 0.820
K55 Vascular disorders of intestine
0.000 0.182 0.818
J86.0 Pyothorax with fistula
0.000 0.183 0.817
I20.0 Unstable angina
0.000 0.184 0.816
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.186 0.814
K51.5 Mucosal proctocolitis
0.805 0.195 0.000
H27 Other disorders of lens
0.000 0.195 0.805
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.804 0.196 0.000
M07.3 Other psoriatic arthropathies
0.000 0.196 0.804
K75.9 Inflammatory liver disease, unspecified
0.000 0.197 0.803
I12.9 Hypertensive renal disease without renal failure
0.000 0.199 0.801
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.200 0.800
E13.9 Without complications
0.000 0.202 0.798
H34.8 Other retinal vascular occlusions
0.000 0.203 0.797
E16.1 Other hypoglycaemia
0.000 0.203 0.797
M14 Arthropathies in other diseases classified elsewhere
0.000 0.205 0.795
E88 Other metabolic disorders
0.000 0.206 0.793
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.210 0.790
E40-E46 Malnutrition
0.000 0.211 0.789
E78.1 Pure hyperglyceridaemia
0.000 0.212 0.788
H40.5 Glaucoma secondary to other eye disorders
0.000 0.214 0.786
K63.4 Enteroptosis
0.000 0.214 0.786
M75 Shoulder lesions
0.000 0.217 0.783
K50.0 Crohn's disease of small intestine
0.000 0.218 0.782
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.220 0.780
K74.6 Other and unspecified cirrhosis of liver
0.000 0.222 0.778
K86.1 Other chronic pancreatitis
0.000 0.224 0.776
J37 Chronic laryngitis and laryngotracheitis
0.000 0.224 0.776
J32 Chronic sinusitis
0.000 0.229 0.771
K82.9 Disease of gallbladder, unspecified
0.000 0.231 0.769
K90.9 Intestinal malabsorption, unspecified
0.000 0.233 0.767
E11.0 With coma
0.000 0.235 0.765
I12.0 Hypertensive renal disease with renal failure
0.000 0.235 0.765
E78.2 Mixed hyperlipidaemia
0.000 0.237 0.763
J98 Other respiratory disorders
0.000 0.237 0.763
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.239 0.761
Chapter VIII Diseases of the ear and mastoid process
0.000 0.240 0.760
H25 Senile cataract
0.000 0.244 0.756
L43.8 Other lichen planus
0.000 0.244 0.756
M75.0 Adhesive capsulitis of shoulder
0.000 0.244 0.756
K86.3 Pseudocyst of pancreas
0.000 0.244 0.756
H34.2 Other retinal artery occlusions
0.000 0.246 0.754
K72.0 Acute and subacute hepatic failure
0.000 0.246 0.754
H25.1 Senile nuclear cataract
0.000 0.248 0.752
H60-H62 Diseases of external ear
0.000 0.252 0.748
K62 Other diseases of anus and rectum
0.000 0.253 0.747
E83 Disorders of mineral metabolism
0.673 0.256 0.071
H43.9 Disorder of vitreous body, unspecified
0.000 0.259 0.741
K82.3 Fistula of gallbladder
0.000 0.259 0.741
M11 Other crystal arthropathies
0.000 0.260 0.740
J98.4 Other disorders of lung
0.000 0.262 0.738
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.265 0.735
H34.1 Central retinal artery occlusion
0.000 0.265 0.735
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.266 0.734
H61 Other disorders of external ear
0.000 0.267 0.733
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.268 0.731
K82.2 Perforation of gallbladder
0.000 0.269 0.731
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.270 0.730
E11.8 With unspecified complications
0.000 0.271 0.729
E74 Other disorders of carbohydrate metabolism
0.000 0.271 0.729
M72 Fibroblastic disorders
0.000 0.271 0.729
K55.2 Angiodysplasia of colon
0.000 0.273 0.727
I25 Chronic ischaemic heart disease
0.000 0.273 0.727
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.274 0.726
H30 Chorioretinal inflammation
0.000 0.277 0.722
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.278 0.722
H43.2 Crystalline deposits in vitreous body
0.000 0.278 0.722
I23 Certain current complications following acute myocardial infarction
0.000 0.281 0.718
M75.2 Bicipital tendinitis
0.000 0.282 0.718
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
J45.8 Mixed asthma
0.000 0.283 0.717
J45.1 Nonallergic asthma
0.000 0.283 0.717
K51.1 Ulcerative (chronic) ileocolitis
0.717 0.283 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.716 0.284 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
G37.5 Concentric sclerosis [Balo]
0.716 0.284 0.000
G37.4 Subacute necrotising myelitis
0.716 0.284 0.000
G37.2 Central pontine myelinolysis
0.716 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.716 0.284 0.000
G37.0 Diffuse sclerosis
0.716 0.284 0.000
J33.1 Polypoid sinus degeneration
0.000 0.285 0.715
K77 Liver disorders in diseases classified elsewhere
0.000 0.285 0.715
K71 Toxic liver disease
0.000 0.285 0.715
M06.34 Rheumatoid nodule (Hand)
0.000 0.286 0.714
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.286 0.714
H40.4 Glaucoma secondary to eye inflammation
0.000 0.287 0.713
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.288 0.712
I11 Hypertensive heart disease
0.000 0.289 0.711
L40.8 Other psoriasis
0.000 0.290 0.710
K62.4 Stenosis of anus and rectum
0.000 0.290 0.710
E78.6 Lipoprotein deficiency
0.000 0.290 0.710
E78.3 Hyperchylomicronaemia
0.000 0.290 0.710
K51.0 Ulcerative (chronic) enterocolitis
0.709 0.291 0.000
E77 Disorders of glycoprotein metabolism
0.000 0.292 0.708
E76 Disorders of glycosaminoglycan metabolism
0.000 0.292 0.708
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.292 0.708
E72 Other disorders of amino-acid metabolism
0.000 0.292 0.708
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.292 0.708
E70 Disorders of aromatic amino-acid metabolism
0.000 0.292 0.708
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.292 0.708
H43.1 Vitreous haemorrhage
0.000 0.293 0.707
K74.4 Secondary biliary cirrhosis
0.000 0.293 0.707
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.293 0.707
K74.1 Hepatic sclerosis
0.000 0.293 0.707
E05.5 Thyroid crisis or storm
0.000 0.295 0.704
E05.4 Thyrotoxicosis factitia
0.000 0.295 0.704
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.295 0.704
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.295 0.704
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.296 0.704
K55.8 Other vascular disorders of intestine
0.000 0.297 0.703
E11.4 With neurological complications
0.000 0.298 0.702
H27.0 Aphakia
0.000 0.298 0.702
J41 Simple and mucopurulent chronic bronchitis
0.000 0.299 0.701
I00-I02 Acute rheumatic fever
0.000 0.300 0.700
H43.0 Vitreous prolapse
0.000 0.301 0.698
I15.1 Hypertension secondary to other renal disorders
0.000 0.302 0.698
J43.2 Centrilobular emphysema
0.000 0.302 0.698
K62.1 Rectal polyp
0.000 0.302 0.698
M14.6 Neuropathic arthropathy
0.000 0.302 0.698
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.303 0.697
K73.9 Chronic hepatitis, unspecified
0.000 0.303 0.697
I13 Hypertensive heart and renal disease
0.000 0.303 0.697
H42 Glaucoma in diseases classified elsewhere
0.000 0.303 0.697
H61.0 Perichondritis of external ear
0.000 0.304 0.696
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.306 0.694
E06.5 Other chronic thyroiditis
0.000 0.309 0.691
E06.4 Drug-induced thyroiditis
0.000 0.309 0.691
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.309 0.691
E06.1 Subacute thyroiditis
0.000 0.309 0.691
E06.0 Acute thyroiditis
0.000 0.309 0.691
H27.8 Other specified disorders of lens
0.000 0.309 0.691
K86.8 Other specified diseases of pancreas
0.000 0.310 0.690
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.310 0.690
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.311 0.689
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.313 0.687
K75.2 Nonspecific reactive hepatitis
0.000 0.313 0.687
K75.1 Phlebitis of portal vein
0.000 0.313 0.687
L44 Other papulosquamous disorders
0.000 0.316 0.684
L41 Parapsoriasis
0.000 0.316 0.684
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.316 0.684
L43.3 Subacute (active) lichen planus
0.000 0.316 0.684
L43.2 Lichenoid drug reaction
0.000 0.316 0.684
L43.1 Bullous lichen planus
0.000 0.316 0.684
L43.0 Hypertrophic lichen planus
0.000 0.316 0.684
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.317 0.683
H40.6 Glaucoma secondary to drugs
0.000 0.317 0.683
H40.3 Glaucoma secondary to eye trauma
0.000 0.317 0.683
K75.8 Other specified inflammatory liver diseases
0.000 0.319 0.681
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.319 0.681
M12 Other specific arthropathies
0.000 0.319 0.680
J43.8 Other emphysema
0.000 0.320 0.680
J43.1 Panlobular emphysema
0.000 0.320 0.680
J43.0 MacLeod's syndrome
0.000 0.320 0.680
L40.4 Guttate psoriasis
0.000 0.320 0.680
L40.3 Pustulosis palmaris et plantaris
0.000 0.320 0.680
L40.2 Acrodermatitis continua
0.000 0.320 0.680
L40.1 Generalised pustular psoriasis
0.000 0.320 0.680
K50.9 Crohn's disease, unspecified
0.000 0.322 0.678
K63.2 Fistula of intestine
0.000 0.324 0.676
K81.9 Cholecystitis, unspecified
0.000 0.325 0.675
J42 Unspecified chronic bronchitis
0.000 0.325 0.675
I25.5 Ischaemic cardiomyopathy
0.000 0.326 0.674
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.328 0.672
E06.9 Thyroiditis, unspecified
0.000 0.332 0.668
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.333 0.667
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.335 0.665
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.335 0.665
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.335 0.665
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.335 0.665
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.335 0.665
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.335 0.665
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.335 0.665
K80 Cholelithiasis
0.000 0.336 0.664
E84 Cystic fibrosis
0.000 0.336 0.663
E05.8 Other thyrotoxicosis
0.000 0.339 0.661
M10 Gout
0.000 0.340 0.660
K72.1 Chronic hepatic failure
0.000 0.340 0.660
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.340 0.660
H34.0 Transient retinal artery occlusion
0.000 0.341 0.659
M66 Spontaneous rupture of synovium and tendon
0.000 0.341 0.659
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.341 0.659
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.342 0.657
K82.0 Obstruction of gallbladder
0.000 0.345 0.655
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.000 0.345 0.655
H34.9 Retinal vascular occlusion, unspecified
0.000 0.348 0.652
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.348 0.652
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.349 0.651
E07.1 Dyshormogenetic goitre
0.000 0.350 0.650
E07.0 Hypersecretion of calcitonin
0.000 0.350 0.650
E78.8 Other disorders of lipoprotein metabolism
0.000 0.351 0.649
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.352 0.648
L42 Pityriasis rosea
0.000 0.357 0.643
I15.9 Seconday hypertension, unspecified
0.000 0.358 0.642
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.358 0.642
E79 Disorders of purine and pyrimidine metabolism
0.000 0.358 0.641
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.361 0.639
E46 Unspecified protein-energy malnutrition
0.000 0.362 0.638
J32.9 Chronic sinusitis, unspecified
0.000 0.364 0.636
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.364 0.636
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.364 0.636
M07.6 Other enteropathic arthropathies
0.000 0.365 0.635
M07.5 Arthropathy in ulcerative colitis
0.000 0.365 0.635
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.365 0.635
M07.2 Psoriatic spondylitis
0.000 0.365 0.635
M07.1 Arthritis mutilans
0.000 0.365 0.635
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.365 0.635
K62.0 Anal polyp
0.000 0.367 0.633
E13.8 With unspecified complications
0.000 0.367 0.633
E13.7 With multiple complications
0.000 0.367 0.633
E13.6 With other specified complications
0.000 0.367 0.633
E13.5 With peripheral circulatory complications
0.000 0.367 0.633
E13.4 With neurological complications
0.000 0.367 0.633
E13.3 With ophthalmic complications
0.000 0.367 0.633
E13.2 With renal complications
0.000 0.367 0.633
E13.1 With ketoacidosis
0.000 0.367 0.633
E13.0 With coma
0.000 0.367 0.633
J32.4 Chronic pansinusitis
0.000 0.368 0.632
M65.1 Other infective (teno)synovitis
0.000 0.371 0.629
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.372 0.628
J37.0 Chronic laryngitis
0.000 0.373 0.627
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.374 0.626
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.375 0.625
I25.2 Old myocardial infarction
0.000 0.376 0.624
K90.8 Other intestinal malabsorption
0.000 0.377 0.623
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.377 0.622
H61.8 Other specified disorders of external ear
0.000 0.377 0.623
H60 Otitis externa
0.000 0.380 0.620
E03.1 Congenital hypothyroidism without goitre
0.000 0.382 0.618
K74.0 Hepatic fibrosis
0.000 0.382 0.618
J60-J70 Lung diseases due to external agents
0.000 0.383 0.617
J98.6 Disorders of diaphragm
0.000 0.384 0.616
M76 Enthesopathies of lower limb, excluding foot
0.000 0.384 0.616
H61.1 Non-infective disorders of pinna
0.000 0.386 0.614
M70.4 Prepatellar bursitis
0.000 0.387 0.612
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.388 0.612
M06.38 Rheumatoid nodule (Other)
0.000 0.388 0.612
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.388 0.612
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.388 0.612
M06.33 Rheumatoid nodule (Forearm)
0.000 0.388 0.612
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.388 0.612
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.388 0.612
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.388 0.612
M77.8 Other enthesopathies, not elsewhere classified
0.000 0.388 0.612
M77.3 Calcaneal spur
0.000 0.388 0.612
M77.2 Periarthritis of wrist
0.000 0.388 0.612
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.389 0.611
K81.8 Other cholecystitis
0.000 0.389 0.611
K55.1 Chronic vascular disorders of intestine
0.000 0.390 0.610
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.390 0.610
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.391 0.609
J85 Abscess of lung and mediastinum
0.000 0.391 0.608
H61.3 Acquired stenosis of external ear canal
0.000 0.392 0.608
L10-L14 Bullous disorders
0.000 0.392 0.607
H27.1 Dislocation of lens
0.000 0.395 0.605
M77.19 Lateral epicondylitis (Site unspecified)
0.000 0.395 0.605
M77.18 Lateral epicondylitis-Other
0.000 0.395 0.605
M77.17 Lateral epicondylitis-Ankle/Foot
0.000 0.395 0.605
M77.16 Lateral epicondylitis (Lower leg)
0.000 0.395 0.605
M77.15 Lateral epicondylitis (Pelvic region and thigh)
0.000 0.395 0.605
M77.14 Lateral epicondylitis-Hand
0.000 0.395 0.605
M77.13 Lateral epicondylitis-Forearm
0.000 0.395 0.605
M77.11 Lateral epicondylitis-Shldr region
0.000 0.395 0.605
M77.10 Lateral epicondylitis (Multiple sites)
0.000 0.395 0.605
K62.7 Radiation proctitis
0.000 0.395 0.605
M77.5 Other enthesopathy of foot
0.000 0.395 0.605
E83.3 Disorders of phosphorus metabolism
0.581 0.395 0.024
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.000 0.397 0.603
M45-M49 Spondylopathies
0.000 0.398 0.602
E88.2 Lipomatosis, not elsewhere classified
0.000 0.398 0.602
J96 Respiratory failure, not elsewhere classified
0.000 0.399 0.601
M77.0 Medial epicondylitis
0.000 0.399 0.601
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.400 0.600
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.400 0.599
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.400 0.599
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.400 0.599
E73 Lactose intolerance
0.000 0.402 0.598
M71 Other bursopathies
0.000 0.403 0.597
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.404 0.596
M65.2 Calcific tendinitis
0.000 0.404 0.596
M65.0 Abscess of tendon sheath
0.000 0.404 0.596
I15.8 Other secondary hypertension
0.000 0.406 0.594
I15.2 Hypertension secondary to endocrine disorders
0.000 0.406 0.594

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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