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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9270022
log Bayes Factor = 213.905
Chromosome 6   position 32,553,142  (GRCh37) Explore rs9270022 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10.4 With neurological complications
0.000 0.001 0.999
J44 Other chronic obstructive pulmonary disease
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
Chapter VII Diseases of the eye and adnexa
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.001 0.000
G37 Other demyelinating diseases of central nervous system
0.998 0.002 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
G37.9 Demyelinating disease of central nervous system, unspecified
0.997 0.003 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.003 0.997
E83.1 Disorders of iron metabolism
0.997 0.003 0.000
E14.3 With ophthalmic complications
0.000 0.004 0.996
K70-K77 Diseases of liver
0.000 0.004 0.996
J33.9 Nasal polyp, unspecified
0.000 0.006 0.994
E78.0 Pure hypercholesterolaemia
0.000 0.006 0.994
J33 Nasal polyp
0.000 0.006 0.994
K50-K52 Noninfective enteritis and colitis
0.001 0.006 0.993
K51.3 Ulcerative (chronic) rectosigmoiditis
0.994 0.006 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.009 0.991
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.011 0.989
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.013 0.987
E70-E90 Metabolic disorders
0.000 0.014 0.985
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.015 0.985
Chapter IX Diseases of the circulatory system
0.000 0.016 0.984
K74 Fibrosis and cirrhosis of liver
0.000 0.016 0.984
I20-I25 Ischaemic heart diseases
0.000 0.017 0.983
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.017 0.983
H40-H42 Glaucoma
0.000 0.018 0.982
J30-J39 Other diseases of upper respiratory tract
0.000 0.020 0.980
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.020 0.980
E10.5 With peripheral circulatory complications
0.000 0.021 0.979
J33.8 Other polyp of sinus
0.000 0.022 0.978
H43-H45 Disorders of vitreous body and globe
0.000 0.022 0.978
I10-I15 Hypertensive diseases
0.000 0.022 0.978
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.024 0.976
K50 Crohn's disease [regional enteritis]
0.000 0.024 0.976
E11.3 With ophthalmic complications
0.000 0.025 0.975
K82 Other diseases of gallbladder
0.000 0.025 0.975
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.028 0.972
L40-L45 Papulosquamous disorders
0.000 0.030 0.970
L43 Lichen planus
0.000 0.031 0.969
H40 Glaucoma
0.000 0.031 0.969
H43 Disorders of vitreous body
0.000 0.031 0.969
L43.9 Lichen planus, unspecified
0.000 0.031 0.969
K82.8 Other specified diseases of gallbladder
0.000 0.032 0.968
K74.3 Primary biliary cirrhosis
0.000 0.032 0.968
E11.1 With ketoacidosis
0.000 0.035 0.965
I22 Subsequent myocardial infarction
0.000 0.037 0.963
H40.9 Glaucoma, unspecified
0.000 0.037 0.963
L40 Psoriasis
0.000 0.037 0.963
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.039 0.961
E05.9 Thyrotoxicosis, unspecified
0.000 0.040 0.960
I10 Essential (primary) hypertension
0.000 0.043 0.957
L40.5 Arthropathic psoriasis
0.000 0.046 0.954
J43 Emphysema
0.000 0.046 0.954
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.047 0.953
I20 Angina pectoris
0.000 0.048 0.952
E06 Thyroiditis
0.000 0.050 0.950
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.052 0.948
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.054 0.946
J46 Status asthmaticus
0.000 0.057 0.943
K51.8 Other ulcerative colitis
0.943 0.057 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.061 0.939
J86 Pyothorax
0.000 0.062 0.938
E10.2 With renal complications
0.000 0.062 0.938
K75 Other inflammatory liver diseases
0.000 0.066 0.934
K72 Hepatic failure, not elsewhere classified
0.000 0.067 0.933
H34 Retinal vascular occlusions
0.000 0.070 0.930
H43.3 Other vitreous opacities
0.000 0.073 0.927
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.077 0.923
K52 Other non-infective gastro-enteritis and colitis
0.000 0.079 0.921
E06.3 Autoimmune thyroiditis
0.000 0.082 0.918
M06.0 Seronegative rheumatoid arthritis
0.000 0.084 0.916
J43.9 Emphysema, unspecified
0.000 0.085 0.915
E11.5 With peripheral circulatory complications
0.000 0.090 0.910
K55-K64 Other diseases of intestines
0.000 0.090 0.910
K50.1 Crohn's disease of large intestine
0.000 0.091 0.909
H43.8 Other disorders of vitreous body
0.000 0.092 0.908
K75.4 Autoimmune hepatitis
0.000 0.096 0.904
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.096 0.904
I20.1 Angina pectoris with documented spasm
0.000 0.098 0.902
M07 Psoriatic and enteropathic arthropathies
0.000 0.100 0.900
J86.9 Pyothorax without fistula
0.000 0.101 0.899
E03.8 Other specified hypothyroidism
0.000 0.103 0.897
H40.1 Primary open-angle glaucoma
0.000 0.106 0.894
K51.2 Ulcerative (chronic) proctitis
0.889 0.111 0.000
E13 Other specified diabetes mellitus
0.000 0.111 0.889
K86 Other diseases of pancreas
0.000 0.113 0.887
K60 Fissure and fistula of anal and rectal regions
0.000 0.113 0.887
K82.1 Hydrops of gallbladder
0.000 0.117 0.883
K50.8 Other Crohn's disease
0.000 0.121 0.879
E11.2 With renal complications
0.000 0.121 0.879
E11.6 With other specified complications
0.000 0.124 0.876
K58 Irritable bowel syndrome
0.000 0.131 0.869
I20.9 Angina pectoris, unspecified
0.000 0.132 0.868
M65-M68 Disorders of synovium and tendon
0.000 0.134 0.866
I24 Other acute ischaemic heart diseases
0.000 0.134 0.866
I12 Hypertensive renal disease
0.000 0.135 0.865
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.136 0.864
E07 Other disorders of thyroid
0.000 0.137 0.863
K74.5 Biliary cirrhosis, unspecified
0.000 0.140 0.860
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.143 0.857
M06.3 Rheumatoid nodule
0.000 0.149 0.851
I25 Chronic ischaemic heart disease
0.000 0.152 0.848
K51.4 Pseudopolyposis of colon
0.844 0.155 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.159 0.841
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.160 0.840
K52.1 Toxic gastro-enteritis and colitis
0.000 0.161 0.838
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.162 0.838
K72.9 Hepatic failure, unspecified
0.000 0.164 0.836
K60.0 Acute anal fissure
0.000 0.164 0.836
J33.0 Polyp of nasal cavity
0.000 0.167 0.833
K60.2 Anal fissure, unspecified
0.000 0.167 0.833
J86.0 Pyothorax with fistula
0.000 0.169 0.831
I20.0 Unstable angina
0.000 0.169 0.831
I15 Secondary hypertension
0.000 0.171 0.829
M07.3 Other psoriatic arthropathies
0.000 0.171 0.829
M70-M79 Other soft tissue disorders
0.000 0.173 0.827
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.176 0.824
G37.8 Other specified demyelinating diseases of central nervous system
0.823 0.177 0.000
L40.9 Psoriasis, unspecified
0.000 0.178 0.822
J95-J99 Other diseases of the respiratory system
0.000 0.180 0.820
K63 Other diseases of intestine
0.000 0.180 0.820
K81 Cholecystitis
0.000 0.180 0.820
H34.8 Other retinal vascular occlusions
0.000 0.181 0.819
Chapter VIII Diseases of the ear and mastoid process
0.000 0.182 0.818
H40.5 Glaucoma secondary to other eye disorders
0.000 0.185 0.815
K73 Chronic hepatitis, not elsewhere classified
0.000 0.185 0.815
H25-H28 Disorders of lens
0.000 0.185 0.815
K86.2 Cyst of pancreas
0.000 0.187 0.813
K72.0 Acute and subacute hepatic failure
0.000 0.189 0.811
E13.9 Without complications
0.000 0.191 0.809
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.808 0.191 0.000
H60-H62 Diseases of external ear
0.000 0.193 0.807
E78.5 Hyperlipidaemia, unspecified
0.000 0.193 0.807
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.193 0.807
I25.5 Ischaemic cardiomyopathy
0.000 0.194 0.806
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.195 0.805
M65 Synovitis and tenosynovitis
0.000 0.195 0.805
K63.9 Disease of intestine, unspecified
0.000 0.197 0.803
K50.0 Crohn's disease of small intestine
0.000 0.199 0.801
E40-E46 Malnutrition
0.000 0.203 0.797
E16.1 Other hypoglycaemia
0.000 0.205 0.795
M14 Arthropathies in other diseases classified elsewhere
0.000 0.209 0.791
H61 Other disorders of external ear
0.000 0.210 0.790
E88 Other metabolic disorders
0.000 0.213 0.787
K51.5 Mucosal proctocolitis
0.786 0.214 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.216 0.784
E78.1 Pure hyperglyceridaemia
0.000 0.216 0.784
K90.9 Intestinal malabsorption, unspecified
0.000 0.217 0.783
K60.5 Anorectal fistula
0.000 0.218 0.782
E78.2 Mixed hyperlipidaemia
0.000 0.221 0.779
E83 Disorders of mineral metabolism
0.703 0.221 0.075
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.224 0.776
H34.2 Other retinal artery occlusions
0.000 0.228 0.772
J37 Chronic laryngitis and laryngotracheitis
0.000 0.230 0.769
K82.9 Disease of gallbladder, unspecified
0.000 0.233 0.767
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.233 0.767
K81.1 Chronic cholecystitis
0.000 0.233 0.767
L43.8 Other lichen planus
0.000 0.234 0.766
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.235 0.765
I12.9 Hypertensive renal disease without renal failure
0.000 0.236 0.764
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.237 0.763
E11.0 With coma
0.000 0.238 0.762
M77 Other enthesopathies
0.000 0.239 0.761
K50.9 Crohn's disease, unspecified
0.000 0.240 0.760
H27 Other disorders of lens
0.000 0.242 0.758
J32 Chronic sinusitis
0.000 0.243 0.757
H61.0 Perichondritis of external ear
0.000 0.245 0.755
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.246 0.754
M77.1 Lateral epicondylitis
0.000 0.251 0.749
K75.9 Inflammatory liver disease, unspecified
0.000 0.253 0.747
H43.2 Crystalline deposits in vitreous body
0.000 0.257 0.743
M11 Other crystal arthropathies
0.000 0.257 0.743
H34.1 Central retinal artery occlusion
0.000 0.258 0.742
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.258 0.742
K55 Vascular disorders of intestine
0.000 0.264 0.736
H43.9 Disorder of vitreous body, unspecified
0.000 0.265 0.735
J98 Other respiratory disorders
0.000 0.267 0.733
K63.3 Ulcer of intestine
0.000 0.267 0.733
K74.6 Other and unspecified cirrhosis of liver
0.000 0.270 0.730
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.271 0.729
K86.1 Other chronic pancreatitis
0.000 0.272 0.728
I25.2 Old myocardial infarction
0.000 0.273 0.727
K82.3 Fistula of gallbladder
0.000 0.274 0.726
E11.8 With unspecified complications
0.000 0.274 0.726
E74 Other disorders of carbohydrate metabolism
0.000 0.275 0.725
H40.4 Glaucoma secondary to eye inflammation
0.000 0.275 0.724
J43.2 Centrilobular emphysema
0.000 0.276 0.724
I23 Certain current complications following acute myocardial infarction
0.000 0.277 0.723
H30 Chorioretinal inflammation
0.000 0.279 0.721
K86.3 Pseudocyst of pancreas
0.000 0.279 0.721
L40.8 Other psoriasis
0.000 0.281 0.719
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
J45.8 Mixed asthma
0.000 0.283 0.717
J45.1 Nonallergic asthma
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
K51.1 Ulcerative (chronic) ileocolitis
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.716 0.284 0.000
G37.5 Concentric sclerosis [Balo]
0.715 0.284 0.000
G37.4 Subacute necrotising myelitis
0.715 0.284 0.000
G37.2 Central pontine myelinolysis
0.715 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.715 0.284 0.000
G37.0 Diffuse sclerosis
0.715 0.284 0.000
K77 Liver disorders in diseases classified elsewhere
0.000 0.286 0.714
K71 Toxic liver disease
0.000 0.286 0.714
K82.2 Perforation of gallbladder
0.000 0.286 0.714
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.286 0.714
J33.1 Polypoid sinus degeneration
0.000 0.287 0.713
M75 Shoulder lesions
0.000 0.288 0.712
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.289 0.711
M06.34 Rheumatoid nodule (Hand)
0.000 0.291 0.709
E78.6 Lipoprotein deficiency
0.000 0.291 0.709
E78.3 Hyperchylomicronaemia
0.000 0.291 0.709
I11 Hypertensive heart disease
0.000 0.292 0.708
E77 Disorders of glycoprotein metabolism
0.000 0.293 0.706
E76 Disorders of glycosaminoglycan metabolism
0.000 0.293 0.706
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.293 0.706
E72 Other disorders of amino-acid metabolism
0.000 0.293 0.706
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.293 0.706
E70 Disorders of aromatic amino-acid metabolism
0.000 0.293 0.706
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.293 0.706
H43.1 Vitreous haemorrhage
0.000 0.295 0.705
I00-I02 Acute rheumatic fever
0.000 0.295 0.705
K74.4 Secondary biliary cirrhosis
0.000 0.295 0.705
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.295 0.705
K74.1 Hepatic sclerosis
0.000 0.295 0.705
H42 Glaucoma in diseases classified elsewhere
0.000 0.296 0.704
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.297 0.703
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.299 0.701
I13 Hypertensive heart and renal disease
0.000 0.299 0.701
J41 Simple and mucopurulent chronic bronchitis
0.000 0.300 0.700
J98.4 Other disorders of lung
0.000 0.300 0.700
K51.0 Ulcerative (chronic) enterocolitis
0.699 0.301 0.000
E05.5 Thyroid crisis or storm
0.000 0.303 0.697
E05.4 Thyrotoxicosis factitia
0.000 0.303 0.697
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.303 0.697
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.303 0.697
K63.4 Enteroptosis
0.000 0.304 0.696
I15.1 Hypertension secondary to other renal disorders
0.000 0.304 0.696
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.304 0.696
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.304 0.696
L44 Other papulosquamous disorders
0.000 0.305 0.695
L41 Parapsoriasis
0.000 0.305 0.695
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.305 0.695
E11.4 With neurological complications
0.000 0.305 0.695
H40.6 Glaucoma secondary to drugs
0.000 0.305 0.695
H40.3 Glaucoma secondary to eye trauma
0.000 0.305 0.695
L43.3 Subacute (active) lichen planus
0.000 0.305 0.695
L43.2 Lichenoid drug reaction
0.000 0.305 0.695
L43.1 Bullous lichen planus
0.000 0.305 0.695
L43.0 Hypertrophic lichen planus
0.000 0.305 0.695
H43.0 Vitreous prolapse
0.000 0.305 0.695
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.305 0.695
M75.0 Adhesive capsulitis of shoulder
0.000 0.306 0.694
H60 Otitis externa
0.000 0.306 0.694
M14.6 Neuropathic arthropathy
0.000 0.308 0.692
L40.4 Guttate psoriasis
0.000 0.310 0.690
L40.3 Pustulosis palmaris et plantaris
0.000 0.310 0.690
L40.2 Acrodermatitis continua
0.000 0.310 0.690
L40.1 Generalised pustular psoriasis
0.000 0.310 0.690
J43.8 Other emphysema
0.000 0.316 0.684
J43.1 Panlobular emphysema
0.000 0.316 0.684
J43.0 MacLeod's syndrome
0.000 0.316 0.684
E06.5 Other chronic thyroiditis
0.000 0.319 0.681
E06.4 Drug-induced thyroiditis
0.000 0.319 0.681
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.319 0.681
E06.1 Subacute thyroiditis
0.000 0.319 0.681
E06.0 Acute thyroiditis
0.000 0.319 0.681
H27.0 Aphakia
0.000 0.320 0.680
L42 Pityriasis rosea
0.000 0.320 0.680
M12 Other specific arthropathies
0.000 0.320 0.679
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.321 0.679
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.323 0.677
K73.9 Chronic hepatitis, unspecified
0.000 0.323 0.677
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.326 0.674
I12.0 Hypertensive renal disease with renal failure
0.000 0.329 0.671
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.331 0.669
K75.2 Nonspecific reactive hepatitis
0.000 0.331 0.669
K75.1 Phlebitis of portal vein
0.000 0.331 0.669
K72.1 Chronic hepatic failure
0.000 0.331 0.669
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.332 0.668
M72 Fibroblastic disorders
0.000 0.332 0.668
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.333 0.667
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.333 0.667
H34.0 Transient retinal artery occlusion
0.000 0.333 0.667
K81.9 Cholecystitis, unspecified
0.000 0.335 0.665
E84 Cystic fibrosis
0.000 0.338 0.661
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.341 0.659
H61.1 Non-infective disorders of pinna
0.000 0.341 0.659
H34.9 Retinal vascular occlusion, unspecified
0.000 0.342 0.658
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.343 0.657
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.343 0.657
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.343 0.657
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.343 0.657
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.343 0.657
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.343 0.657
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.343 0.657
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.343 0.657
E06.9 Thyroiditis, unspecified
0.000 0.344 0.656
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.345 0.655
K62 Other diseases of anus and rectum
0.000 0.347 0.653
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.347 0.652
H61.3 Acquired stenosis of external ear canal
0.000 0.348 0.652
E46 Unspecified protein-energy malnutrition
0.000 0.348 0.652
H25 Senile cataract
0.000 0.349 0.651
H61.8 Other specified disorders of external ear
0.000 0.350 0.650
M75.2 Bicipital tendinitis
0.000 0.350 0.650
K86.8 Other specified diseases of pancreas
0.000 0.352 0.648
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.352 0.648
M07.6 Other enteropathic arthropathies
0.000 0.354 0.646
M07.5 Arthropathy in ulcerative colitis
0.000 0.354 0.646
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.354 0.646
M07.2 Psoriatic spondylitis
0.000 0.354 0.646
M07.1 Arthritis mutilans
0.000 0.354 0.646
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.354 0.646
M66 Spontaneous rupture of synovium and tendon
0.000 0.356 0.644
H25.1 Senile nuclear cataract
0.000 0.358 0.642
E78.8 Other disorders of lipoprotein metabolism
0.000 0.358 0.642
K82.0 Obstruction of gallbladder
0.000 0.358 0.642
I15.9 Seconday hypertension, unspecified
0.000 0.359 0.641
J42 Unspecified chronic bronchitis
0.000 0.359 0.641
J32.9 Chronic sinusitis, unspecified
0.000 0.361 0.639
E79 Disorders of purine and pyrimidine metabolism
0.000 0.361 0.639
E13.8 With unspecified complications
0.000 0.363 0.637
E13.7 With multiple complications
0.000 0.363 0.637
E13.6 With other specified complications
0.000 0.363 0.637
E13.5 With peripheral circulatory complications
0.000 0.363 0.637
E13.4 With neurological complications
0.000 0.363 0.637
E13.3 With ophthalmic complications
0.000 0.363 0.637
E13.2 With renal complications
0.000 0.363 0.637
E13.1 With ketoacidosis
0.000 0.363 0.637
E13.0 With coma
0.000 0.363 0.637
K55.2 Angiodysplasia of colon
0.000 0.364 0.636
H27.8 Other specified disorders of lens
0.000 0.367 0.632
K55.8 Other vascular disorders of intestine
0.000 0.369 0.631
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.370 0.630
E83.3 Disorders of phosphorus metabolism
0.603 0.371 0.026
J32.4 Chronic pansinusitis
0.000 0.371 0.629
L10-L14 Bullous disorders
0.000 0.372 0.628
M10 Gout
0.000 0.373 0.627
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.373 0.627
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.374 0.626
J85 Abscess of lung and mediastinum
0.000 0.375 0.625
E05.8 Other thyrotoxicosis
0.000 0.377 0.622
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.377 0.622
K62.4 Stenosis of anus and rectum
0.000 0.378 0.622
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.379 0.621
E83.9 Disorder of mineral metabolism, unspecified
0.577 0.379 0.044
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.380 0.620
E07.1 Dyshormogenetic goitre
0.000 0.381 0.619
E07.0 Hypersecretion of calcitonin
0.000 0.381 0.619
J37.0 Chronic laryngitis
0.000 0.382 0.618
E03.1 Congenital hypothyroidism without goitre
0.000 0.383 0.617
L40.0 Psoriasis vulgaris
0.000 0.387 0.613
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.389 0.611
K75.8 Other specified inflammatory liver diseases
0.000 0.390 0.610
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.390 0.610
M06.38 Rheumatoid nodule (Other)
0.000 0.390 0.610
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.390 0.610
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.390 0.610
M06.33 Rheumatoid nodule (Forearm)
0.000 0.390 0.610
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.390 0.610
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.390 0.610
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.390 0.610
K74.0 Hepatic fibrosis
0.000 0.391 0.609
I25.6 Silent myocardial ischaemia
0.000 0.392 0.608
M65.1 Other infective (teno)synovitis
0.000 0.393 0.607
K62.1 Rectal polyp
0.000 0.394 0.606
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.395 0.605
K63.2 Fistula of intestine
0.000 0.395 0.605
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.397 0.603
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.397 0.603
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.397 0.603
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.397 0.603
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.397 0.603
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.397 0.603
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.397 0.603
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.397 0.603
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.000 0.400 0.600
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.401 0.598
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.402 0.597
M45-M49 Spondylopathies
0.000 0.403 0.597
E88.2 Lipomatosis, not elsewhere classified
0.000 0.405 0.595
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.405 0.595
I15.8 Other secondary hypertension
0.000 0.405 0.594
I15.2 Hypertension secondary to endocrine disorders
0.000 0.405 0.594
I15.0 Renovascular hypertension
0.000 0.405 0.594
M07.38 Other psoriatic arthropathies (Other)
0.000 0.405 0.594
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.405 0.594
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.405 0.594
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.405 0.594
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.405 0.594
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.405 0.594
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.405 0.594
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.406 0.593
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.407 0.593
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.407 0.593
G56.0 Carpal tunnel syndrome
0.000 0.407 0.593
J98.6 Disorders of diaphragm
0.000 0.409 0.591
K90.8 Other intestinal malabsorption
0.000 0.409 0.590
J96 Respiratory failure, not elsewhere classified
0.000 0.412 0.588
H60.9 Otitis externa, unspecified
0.000 0.412 0.588
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.416 0.584
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.416 0.584
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.416 0.584
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.416 0.584
I25.4 Coronary artery aneurysm
0.000 0.418 0.582
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.419 0.581
E73 Lactose intolerance
0.000 0.420 0.580
I25.3 Aneurysm of heart
0.000 0.420 0.580
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.421 0.578
M65.2 Calcific tendinitis
0.000 0.423 0.577
M65.0 Abscess of tendon sheath
0.000 0.423 0.577
K81.8 Other cholecystitis
0.000 0.424 0.576

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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