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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9271489
log Bayes Factor = 91.561
Chromosome 6   position 32,589,051  (GRCh37) Explore rs9271489 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
H30-H36 Disorders of choroid and retina
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.999 0.001 0.000
E10.1 With ketoacidosis
0.999 0.001 0.000
E03.9 Hypothyroidism, unspecified
0.999 0.001 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.002 0.998
M15-M19 Arthrosis
0.998 0.002 0.000
M18 Arthrosis of first carpometacarpal joint
0.998 0.002 0.000
E27 Other disorders of adrenal gland
0.998 0.002 0.000
Q60-Q64 Congenital malformations of the urinary system
0.998 0.002 0.000
M06.3 Rheumatoid nodule
0.000 0.003 0.997
E27.1 Primary adrenocortical insufficiency
0.996 0.004 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.995 0.005 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.995 0.005 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.995 0.005 0.000
L40.9 Psoriasis, unspecified
0.000 0.006 0.994
D80-D89 Certain disorders involving the immune mechanism
0.994 0.006 0.000
Q61 Cystic kidney disease
0.993 0.007 0.000
D69 Purpura and other haemorrhagic conditions
0.993 0.007 0.000
M20-M25 Other joint disorders
0.991 0.009 0.000
E16 Other disorders of pancreatic internal secretion
0.991 0.009 0.000
E14 Unspecified diabetes mellitus
0.990 0.010 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.011 0.989
E16.2 Hypoglycaemia, unspecified
0.986 0.014 0.000
M24 Other specific joint derangements
0.985 0.015 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.016 0.984
M24.1 Other articular cartilage disorders
0.981 0.019 0.000
N00-N08 Glomerular diseases
0.981 0.019 0.000
H33 Retinal detachments and breaks
0.980 0.020 0.000
Q61.3 Polycystic kidney, unspecified
0.980 0.020 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.021 0.979
Q38-Q45 Other congenital malformations of the digestive system
0.979 0.021 0.000
D86 Sarcoidosis
0.978 0.022 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.977 0.023 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.024 0.976
E28 Ovarian dysfunction
0.975 0.025 0.000
N04 Nephrotic syndrome
0.975 0.025 0.000
H34 Retinal vascular occlusions
0.975 0.025 0.000
D69.6 Thrombocytopenia, unspecified
0.973 0.027 0.000
H35 Other retinal disorders
0.973 0.027 0.000
N05 Unspecified nephritic syndrome
0.972 0.028 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.029 0.971
M60-M63 Disorders of muscles
0.969 0.031 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.033 0.967
M35 Other systemic involvement of connective tissue
0.967 0.033 0.000
Chapter XIV Diseases of the genitourinary system
0.964 0.036 0.000
H34.8 Other retinal vascular occlusions
0.959 0.041 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.955 0.045 0.000
N04.9 Unspecified
0.955 0.045 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.954 0.046 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.952 0.047 0.000
M35.0 Sicca syndrome [Sjogren]
0.949 0.051 0.000
N17-N19 Renal failure
0.948 0.052 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.947 0.053 0.000
H35.4 Peripheral retinal degeneration
0.947 0.053 0.000
R31 Unspecified haematuria
0.000 0.053 0.947
H33.4 Traction detachment of retina
0.944 0.056 0.000
H06.2 Dysthyroid exophthalmos
0.944 0.056 0.000
E28.2 Polycystic ovarian syndrome
0.943 0.057 0.000
E14.9 Without complications
0.943 0.057 0.000
N18 Chronic renal failure
0.940 0.060 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.061 0.939
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.936 0.064 0.000
Q61.2 Polycystic kidney, adult type
0.936 0.064 0.000
M15 Polyarthrosis
0.935 0.065 0.000
D69.4 Other primary thrombocytopenia
0.933 0.067 0.000
E10.2 With renal complications
0.932 0.068 0.000
Q43 Other congenital malformations of intestine
0.925 0.075 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.925 0.075 0.000
D86.9 Sarcoidosis, unspecified
0.923 0.077 0.000
M62 Other disorders of muscle
0.923 0.077 0.000
N05.2 Diffuse membranous glomerulonephritis
0.922 0.078 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.922 0.078 0.000
H50 Other strabismus
0.921 0.079 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.921 0.079 0.000
M21 Other acquired deformities of limbs
0.921 0.079 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.920 0.080 0.000
N05.9 Unspecified
0.915 0.085 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.085 0.915
H33.1 Retinoschisis and retinal cysts
0.915 0.085 0.000
H35.8 Other specified retinal disorders
0.914 0.086 0.000
E24 Cushing's syndrome
0.914 0.086 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.914 0.086 0.000
H36 Retinal disorders in diseases classified elsewhere
0.909 0.091 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.092 0.908
M21.0 Valgus deformity, not elsewhere classified
0.908 0.092 0.000
E03.8 Other specified hypothyroidism
0.906 0.094 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.906 0.094 0.000
N18.3 Chronic kidney disease, stage 3
0.905 0.095 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.902 0.098 0.000
E27.9 Disorder of adrenal gland, unspecified
0.902 0.098 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.899 0.101 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.894 0.106 0.000
E14.3 With ophthalmic complications
0.891 0.109 0.000
M32 Systemic lupus erythematosus
0.889 0.111 0.000
Q60.0 Renal agenesis, unilateral
0.884 0.116 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.122 0.878
H50.5 Heterophoria
0.876 0.124 0.000
Q00-Q07 Congenital malformations of the nervous system
0.875 0.125 0.000
E10.4 With neurological complications
0.875 0.125 0.000
M62.8 Other specified disorders of muscle
0.874 0.126 0.000
D86.3 Sarcoidosis of skin
0.865 0.135 0.000
N04.2 Diffuse membranous glomerulonephritis
0.861 0.139 0.000
N25-N29 Other disorders of kidney and ureter
0.859 0.141 0.000
M15.1 Heberden's nodes (with arthropathy)
0.858 0.142 0.000
D86.0 Sarcoidosis of lung
0.857 0.143 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.144 0.856
Q44.6 Cystic disease of liver
0.855 0.145 0.000
E10.0 With coma
0.855 0.145 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.149 0.851
H35.0 Background retinopathy and retinal vascular changes
0.851 0.149 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.847 0.153 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.845 0.155 0.000
N04.1 Focal and segmental glomerular lesions
0.845 0.155 0.000
M35.7 Hypermobility syndrome
0.844 0.156 0.000
H36.0 Diabetic retinopathy
0.844 0.156 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.156 0.843
M60 Myositis
0.840 0.160 0.000
Q60.2 Renal agenesis, unspecified
0.839 0.161 0.000
D60-D64 Aplastic and other anaemias
0.834 0.166 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.167 0.833
M86-M90 Other osteopathies
0.832 0.168 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.832 0.168 0.000
N18.2 Chronic kidney disease, stage 2
0.831 0.169 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.830 0.170 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.829 0.171 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.829 0.171 0.000
E28.3 Primary ovarian failure
0.828 0.172 0.000
N17 Acute renal failure
0.828 0.172 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.827 0.173 0.000
N18.5 Chronic kidney disease, stage 5
0.825 0.175 0.000
N18.9 Chronic renal failure, unspecified
0.824 0.176 0.000
E14.8 With unspecified complications
0.823 0.177 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.818 0.182 0.000
E14.1 With ketoacidosis
0.817 0.183 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.817 0.183 0.000
M21.8 Other specified acquired deformities of limbs
0.815 0.185 0.000
M35.1 Other overlap syndromes
0.814 0.186 0.000
H33.0 Retinal detachment with retinal break
0.811 0.189 0.000
D80 Immunodeficiency with predominantly antibody defects
0.807 0.193 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.806 0.194 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.805 0.195 0.000
M14 Arthropathies in other diseases classified elsewhere
0.000 0.195 0.805
E24.2 Drug-induced Cushing's syndrome
0.804 0.196 0.000
H05 Disorders of orbit
0.801 0.199 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.800 0.200 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.797 0.203 0.000
H35.2 Other proliferative retinopathy
0.795 0.205 0.000
H50.2 Vertical strabismus
0.791 0.209 0.000
N05.1 Focal and segmental glomerular lesions
0.790 0.210 0.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.212 0.788
D69.9 Haemorrhagic condition, unspecified
0.786 0.214 0.000
N17.9 Acute renal failure, unspecified
0.782 0.218 0.000
M34 Systemic sclerosis
0.780 0.220 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.220 0.780
Q61.9 Cystic kidney disease, unspecified
0.776 0.224 0.000
E23 Hypofunction and other disorders of pituitary gland
0.775 0.225 0.000
D68 Other coagulation defects
0.774 0.226 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.227 0.773
M24.5 Contracture of joint
0.771 0.229 0.000
H50.6 Mechanical strabismus
0.771 0.229 0.000
E31 Polyglandular dysfunction
0.770 0.229 0.000
E10.7 With multiple complications
0.766 0.234 0.000
M80-M85 Disorders of bone density and structure
0.764 0.236 0.000
D55-D59 Haemolytic anaemias
0.762 0.238 0.000
M17 Gonarthrosis [arthrosis of knee]
0.761 0.239 0.000
M35.2 Behcet's disease
0.761 0.239 0.000
D69.8 Other specified haemorrhagic conditions
0.758 0.242 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.757 0.243 0.000
H35.6 Retinal haemorrhage
0.756 0.244 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.246 0.754
Q30-Q34 Congenital malformations of the respiratory system
0.753 0.246 0.000
E14.2 Withrenal complications
0.752 0.248 0.000
Q44.4 Choledochal cyst
0.752 0.248 0.000
Q43.0 Meckel's diverticulum
0.751 0.249 0.000
Q63 Other congenital malformations of kidney
0.749 0.250 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.251 0.749
D83 Common variable immunodeficiency
0.749 0.251 0.000
Q43.3 Congenital malformations of intestinal fixation
0.748 0.252 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.747 0.253 0.000
M24.7 Protrusio acetabuli
0.747 0.253 0.000
L40 Psoriasis
0.001 0.253 0.746
M24.9 Joint derangement, unspecified
0.744 0.256 0.000
M17.1 Other primary gonarthrosis
0.744 0.256 0.000
H05.2 Exophthalmic conditions
0.743 0.257 0.000
M62.6 Muscle strain
0.742 0.258 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.741 0.259 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.738 0.262 0.000
M60.9 Myositis, unspecified
0.737 0.263 0.000
D64 Other anaemias
0.736 0.264 0.000
E24.0 Pituitary-dependent Cushing's disease
0.730 0.270 0.000
Q05 Spina bifida
0.730 0.270 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.729 0.271 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.728 0.272 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.728 0.272 0.000
Q35-Q37 Cleft lip and cleft palate
0.726 0.273 0.000
H34.2 Other retinal artery occlusions
0.724 0.276 0.000
H33.3 Retinal breaks without detachment
0.719 0.281 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.718 0.282 0.000
D86.8 Sarcoidosis of other and combined sites
0.718 0.282 0.000
N00 Acute nephritic syndrome
0.717 0.283 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E25 Adrenogenital disorders
0.717 0.283 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.716
M05.2 Rheumatoid vasculitis
0.000 0.283 0.716
M05.1 Rheumatoid lung disease
0.000 0.283 0.716
M05.0 Felty's syndrome
0.000 0.283 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.716 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.716
M08 Juvenile arthritis
0.000 0.283 0.716
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.715 0.284 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.715 0.284 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.715 0.284 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.715 0.284 0.000
E27.5 Adrenomedullary hyperfunction
0.715 0.284 0.000
E27.0 Other adrenocortical overactivity
0.715 0.284 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.285 0.715
M06.38 Rheumatoid nodule (Other)
0.000 0.285 0.715
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.285 0.715
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.285 0.715
M06.33 Rheumatoid nodule (Forearm)
0.000 0.285 0.715
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.285 0.715
E15 Nondiabetic hypoglycaemic coma
0.713 0.287 0.000
D81 Combined immunodeficiencies
0.713 0.287 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.712 0.287 0.000
Q61.8 Other cystic kidney diseases
0.712 0.288 0.000
Q61.4 Renal dysplasia
0.712 0.288 0.000
Q61.1 Polycystic kidney, infantile type
0.712 0.288 0.000
M80 Osteoporosis with pathological fracture
0.711 0.289 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.711 0.289 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.710 0.290 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.710 0.290 0.000
E16.4 Abnormal secretion of gastrin
0.710 0.290 0.000
E16.3 Increased secretion of glucagon
0.710 0.290 0.000
E14.7 With multiple complications
0.709 0.290 0.000
E14.0 With coma
0.709 0.290 0.000
M91-M94 Chondropathies
0.709 0.291 0.000
E10.8 With unspecified complications
0.709 0.291 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.291 0.709
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.291 0.709
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.291 0.709
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.291 0.709
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.291 0.709
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.291 0.709
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.291 0.709
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.707 0.293 0.000
H50.8 Other specified strabismus
0.706 0.294 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.704 0.296 0.000
Q40 Other congenital malformations of upper alimentary tract
0.704 0.296 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.704 0.296 0.000
M24.18 Other articular cartilage disorders (Other)
0.704 0.296 0.000
M24.14 Other articular cartilage disorders (Hand)
0.704 0.296 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.704 0.296 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.704 0.296 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.704 0.296 0.000
N06 Isolated proteinuria with specified morphological lesion
0.704 0.296 0.000
N01 Rapidly progressive nephritic syndrome
0.704 0.296 0.000
H49 Paralytic strabismus
0.704 0.296 0.000
H50.9 Strabismus, unspecified
0.703 0.297 0.000
E23.6 Other disorders of pituitary gland
0.703 0.297 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.702 0.298 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.702 0.298 0.000
D69.2 Other nonthrombocytopenic purpura
0.701 0.299 0.000
E16.1 Other hypoglycaemia
0.699 0.301 0.000
E28.9 Ovarian dysfunction, unspecified
0.699 0.301 0.000
E28.8 Other ovarian dysfunction
0.699 0.301 0.000
E28.1 Androgen excess
0.699 0.301 0.000
E28.0 Oestrogen excess
0.699 0.301 0.000
N04.8 Other
0.699 0.301 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.699 0.301 0.000
N04.6 Dense deposit disease
0.699 0.301 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.699 0.301 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.699 0.301 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.699 0.301 0.000
H34.0 Transient retinal artery occlusion
0.699 0.301 0.000
H35.1 Retinopathy of prematurity
0.697 0.303 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.303 0.697
N05.6 Dense deposit disease
0.697 0.303 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.697 0.303 0.000
N05.0 Minor glomerular abnormality
0.697 0.303 0.000
E40-E46 Malnutrition
0.696 0.304 0.000
D69.1 Qualitative platelet defects
0.696 0.304 0.000
Q07 Other congenital malformations of nervous system
0.696 0.304 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.695 0.305 0.000
M61 Calcification and ossification of muscle
0.695 0.305 0.000
L40.5 Arthropathic psoriasis
0.000 0.306 0.694
D61 Other aplastic anaemias
0.694 0.306 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.694 0.306 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.694 0.306 0.000
M35.5 Multifocal fibrosclerosis
0.694 0.306 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.694 0.306 0.000
E14.4 With neurological complications
0.691 0.309 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.691 0.309 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.690 0.310 0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)
0.688 0.312 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.687 0.313 0.000
D68.8 Other specified coagulation defects
0.687 0.313 0.000
H34.1 Central retinal artery occlusion
0.687 0.313 0.000
E26 Hyperaldosteronism
0.686 0.314 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.685 0.315 0.000
Q60.6 Potter's syndrome
0.685 0.315 0.000
Q60.5 Renal hypoplasia, unspecified
0.685 0.315 0.000
Q60.4 Renal hypoplasia, bilateral
0.685 0.315 0.000
Q60.3 Renal hypoplasia, unilateral
0.685 0.315 0.000
Q60.1 Renal agenesis, bilateral
0.685 0.315 0.000
E24.9 Cushing's syndrome, unspecified
0.685 0.315 0.000
M15.4 Erosive (osteo)arthrosis
0.684 0.316 0.000
E14.5 With peripheral circulatory complications
0.684 0.316 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.684 0.316 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.684 0.316 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.684 0.316 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.684 0.316 0.000
M62.89 Other specified disorders of muscle (Site unspecified)
0.683 0.317 0.000
M15.8 Other polyarthrosis
0.681 0.319 0.000
E24.8 Other Cushing's syndrome
0.681 0.319 0.000
H50.0 Convergent concomitant strabismus
0.680 0.320 0.000
H06.3 Other disorders of orbit in diseases classified elsewhere
0.679 0.321 0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.679 0.321 0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.679 0.321 0.000
H00.1 Chalazion
0.000 0.323 0.677
Q61.0 Congenital single renal cyst
0.677 0.323 0.000
D69.0 Allergic purpura
0.676 0.324 0.000
M21.4 Flat foot [pes planus] (acquired)
0.674 0.325 0.000
M21.9 Acquired deformity of limb, unspecified
0.674 0.326 0.000
D67 Hereditary factor IX deficiency
0.674 0.326 0.000
D84 Other immunodeficiencies
0.673 0.327 0.000
E20 Hypoparathyroidism
0.672 0.328 0.000
Q44.5 Other congenital malformations of bile ducts
0.672 0.328 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.671 0.329 0.000
M15.0 Primary generalised (osteo)arthrosis
0.670 0.330 0.000
Q43.8 Other specified congenital malformations of intestine
0.670 0.330 0.000
M88 Paget's disease of bone [osteitis deformans]
0.670 0.330 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.670 0.330 0.000
H30 Chorioretinal inflammation
0.670 0.330 0.000
M90 Osteopathies in diseases classified elsewhere
0.670 0.330 0.000
E06 Thyroiditis
0.669 0.330 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.666 0.334 0.000
H34.9 Retinal vascular occlusion, unspecified
0.666 0.334 0.000
M11 Other crystal arthropathies
0.000 0.334 0.665
D86.1 Sarcoidosis of lymph nodes
0.665 0.335 0.000
Q43.7 Persistent cloaca
0.663 0.336 0.000
Q43.6 Congenital fistula of rectum and anus
0.663 0.336 0.000
Q43.5 Ectopic anus
0.663 0.336 0.000
Q43.4 Duplication of intestine
0.663 0.336 0.000
Q43.2 Other congenital functional disorders of colon
0.663 0.336 0.000
D50-D53 Nutritional anaemias
0.662 0.338 0.000
M62.9 Disorder of muscle, unspecified
0.662 0.338 0.000
M62.4 Contracture of muscle
0.662 0.338 0.000
M62.3 Immobility syndrome (paraplegic)
0.662 0.338 0.000
M62.2 Ischaemic infarction of muscle
0.662 0.338 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.661 0.339 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.661 0.339 0.000
H50.3 Intermittent heterotropia
0.661 0.339 0.000
Q44.7 Other congenital malformations of liver
0.660 0.340 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.660 0.340 0.000
Q44.2 Atresia of bile ducts
0.660 0.340 0.000
Q44.1 Other congenital malformations of gallbladder
0.660 0.340 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.660 0.340 0.000
E07 Other disorders of thyroid
0.660 0.340 0.000
M15.9 Polyarthrosis, unspecified
0.660 0.340 0.000
M60.99 Myositis, unspecified (Site unspecified)
0.659 0.341 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.659 0.341 0.000
D64.9 Anaemia, unspecified
0.658 0.342 0.000
N28.0 Ischaemia and infarction of kidney
0.656 0.344 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.655 0.345 0.000
E24.3 Ectopic ACTH syndrome
0.655 0.345 0.000
E24.1 Nelson's syndrome
0.655 0.345 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.655 0.345 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.654 0.346 0.000
Q03 Congenital hydrocephalus
0.653 0.346 0.000
D89.1 Cryoglobulinaemia
0.653 0.347 0.000
H43-H45 Disorders of vitreous body and globe
0.652 0.348 0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)
0.652 0.348 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.651 0.348 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.651 0.349 0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)
0.651 0.349 0.000
M21.08 Valgus deformity, not elsewhere classified (Other)
0.651 0.349 0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)
0.651 0.349 0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)
0.651 0.349 0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)
0.651 0.349 0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)
0.651 0.349 0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)
0.651 0.349 0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)
0.651 0.349 0.000
M60.2 Foreign body granuloma of soft tissue, not elsewhere classified
0.650 0.349 0.000
H50.1 Divergent concomitant strabismus
0.650 0.350 0.000
D89.3 Immune reconstitution syndrome
0.649 0.350 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.648 0.352 0.000
D82 Immunodeficiency associated with other major defects
0.647 0.353 0.000
Q63.2 Ectopic kidney
0.645 0.355 0.000
D68.0 Von Willebrand's disease
0.645 0.355 0.000
I12 Hypertensive renal disease
0.644 0.356 0.000
N04.0 Minor glomerular abnormality
0.644 0.356 0.000
N03 Chronic nephritic syndrome
0.643 0.357 0.000
I12.9 Hypertensive renal disease without renal failure
0.643 0.357 0.000
M14.6 Neuropathic arthropathy
0.000 0.358 0.642
Q39 Congenital malformations of oesophagus
0.642 0.358 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.642 0.358 0.000
M82 Osteoporosis in diseases classified elsewhere
0.641 0.359 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.640 0.360 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.640 0.360 0.000
Chapter IX Diseases of the circulatory system
0.640 0.360 0.000
Q04 Other congenital malformations of brain
0.640 0.360 0.000
M60.8 Other myositis
0.639 0.361 0.000
M24.56 Contracture of joint (Lower leg)
0.639 0.361 0.000
E14.6 With other specified complications
0.638 0.361 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.638 0.362 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.638 0.362 0.000
M07.3 Other psoriatic arthropathies
0.000 0.363 0.637
I70-I79 Diseases of arteries, arterioles and capillaries
0.637 0.363 0.000
I10-I15 Hypertensive diseases
0.637 0.363 0.000
Q43.1 Hirschsprung's disease
0.636 0.364 0.000
N18.1 Chronic kidney disease, stage 1
0.635 0.364 0.000
D68.6 Other Thrombophilia
0.633 0.367 0.000
N05.8 Other
0.632 0.367 0.000
M32.8 Other forms of systemic lupus erythematosus
0.632 0.368 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.369 0.631
E02 Subclinical iodine-deficiency hypothyroidism
0.631 0.369 0.000
M86 Osteomyelitis
0.629 0.371 0.000
M24.6 Ankylosis of joint
0.628 0.372 0.000
M34.0 Progressive systemic sclerosis
0.628 0.372 0.000
Q06 Other congenital malformations of spinal cord
0.627 0.373 0.000
Q01 Encephalocele
0.627 0.373 0.000
Q00 Anencephaly and similar malformations
0.627 0.373 0.000
Q02 Microcephaly
0.627 0.373 0.000
Q45 Other congenital malformations of digestive system
0.627 0.373 0.000
M62.87 Other specified disorders of muscle (Ankle and foot)
0.627 0.373 0.000
M65-M68 Disorders of synovium and tendon
0.626 0.374 0.000
M22 Disorders of patella
0.626 0.374 0.000
E27.2 Addisonian crisis
0.624 0.376 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.624 0.376 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.623 0.376 0.000
N18.0 End-stage renal disease
0.623 0.377 0.000
D58 Other hereditary haemolytic anaemias
0.621 0.379 0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)
0.619 0.381 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.619 0.381 0.000
H35.5 Hereditary retinal dystrophy
0.619 0.381 0.000
M15.3 Secondary multiple arthrosis
0.619 0.381 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.617 0.383 0.000
Q61.5 Medullary cystic kidney
0.615 0.385 0.000
D68.5 Primary Thrombophilia
0.613 0.387 0.000
M62.0 Diastasis of muscle
0.613 0.387 0.000
M12 Other specific arthropathies
0.000 0.388 0.612
H00 Hordeolum and chalazion
0.207 0.389 0.404
N18.4 Chronic kidney disease, stage 4
0.611 0.389 0.000
N25 Disorders resulting from impaired renal tubular function
0.611 0.389 0.000
H50.4 Other and unspecified heterotropia
0.609 0.391 0.000
M93 Other osteochondropathies
0.608 0.392 0.000
M62.65 Muscle strain (Pelvic region and thigh)
0.607 0.392 0.000
D61.9 Aplastic anaemia, unspecified
0.607 0.393 0.000
E31.0 Autoimmune polyglandular failure
0.606 0.394 0.000
M83 Adult osteomalacia
0.606 0.394 0.000
H51 Other disorders of binocular movement
0.605 0.395 0.000
N27 Small kidney of unknown cause
0.605 0.395 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.604 0.396 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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