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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9272219
log Bayes Factor = 165.087
Chromosome 6   position 32,602,269  (GRCh37) Explore rs9272219 on Ensembl!
Variant rs9272219 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
D50-D53 Nutritional anaemias
1.000 0.000 0.000
N00-N08 Glomerular diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
1.000 0.000 0.000
E27 Other disorders of adrenal gland
1.000 0.000 0.000
E27.1 Primary adrenocortical insufficiency
1.000 0.000 0.000
D50 Iron deficiency anaemia
1.000 0.000 0.000
D69 Purpura and other haemorrhagic conditions
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
0.001 0.000 0.999
N05 Unspecified nephritic syndrome
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.000 0.001 0.999
M35.0 Sicca syndrome [Sjogren]
0.999 0.001 0.000
N04 Nephrotic syndrome
0.999 0.001 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.999 0.001 0.000
D50.9 Iron deficiency anaemia, unspecified
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.998 0.002 0.000
H06.2 Dysthyroid exophthalmos
0.998 0.002 0.000
D69.6 Thrombocytopenia, unspecified
0.998 0.002 0.000
E16 Other disorders of pancreatic internal secretion
0.998 0.002 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.003 0.997
E16.2 Hypoglycaemia, unspecified
0.996 0.004 0.000
M35 Other systemic involvement of connective tissue
0.996 0.004 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.004 0.996
E14.3 With ophthalmic complications
0.996 0.004 0.000
M06.3 Rheumatoid nodule
0.000 0.005 0.995
M20-M25 Other joint disorders
0.994 0.006 0.000
I77 Other disorders of arteries and arterioles
0.994 0.006 0.000
N04.9 Unspecified
0.994 0.006 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.994 0.006 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.992 0.008 0.000
I74 Arterial embolism and thrombosis
0.990 0.010 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.990 0.010 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.989 0.011 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.989 0.011 0.000
D80-D89 Certain disorders involving the immune mechanism
0.988 0.012 0.000
G56.0 Carpal tunnel syndrome
0.988 0.012 0.000
C81 Hodgkin's disease
0.988 0.012 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.987 0.013 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.986 0.014 0.000
G56 Mononeuropathies of upper limb
0.986 0.014 0.000
I10-I15 Hypertensive diseases
0.986 0.014 0.000
D51 Vitamin B12 deficiency anaemia
0.986 0.014 0.000
I12 Hypertensive renal disease
0.985 0.015 0.000
Chapter XIV Diseases of the genitourinary system
0.984 0.016 0.000
Chapter II Neoplasms
0.984 0.016 0.000
Chapter VI Diseases of the nervous system
0.983 0.017 0.000
D00-D09 In situ neoplasms
0.983 0.017 0.000
N17-N19 Renal failure
0.981 0.019 0.000
E11 Non-insulin-dependent diabetes mellitus
0.980 0.020 0.000
I12.0 Hypertensive renal disease with renal failure
0.980 0.020 0.000
N05.2 Diffuse membranous glomerulonephritis
0.979 0.021 0.000
N18 Chronic renal failure
0.979 0.021 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.978 0.022 0.000
H50 Other strabismus
0.977 0.023 0.000
D04 Carcinoma in situ of skin
0.975 0.025 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.972 0.026 0.003
C83.3 Large cell (diffuse)
0.974 0.026 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.028 0.972
E11.3 With ophthalmic complications
0.972 0.028 0.000
E21.3 Hyperparathyroidism, unspecified
0.970 0.030 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.030 0.970
I77.9 Disorder of arteries and arterioles, unspecified
0.970 0.030 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.970 0.030 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.970 0.030 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.966 0.034 0.000
N40 Hyperplasia of prostate
0.000 0.035 0.965
E10.2 With renal complications
0.964 0.036 0.000
E10.4 With neurological complications
0.963 0.037 0.000
M24 Other specific joint derangements
0.963 0.037 0.000
D86 Sarcoidosis
0.962 0.038 0.000
H34 Retinal vascular occlusions
0.961 0.039 0.000
C81.9 Hodgkin's disease, unspecified
0.959 0.041 0.000
L82 Seborrhoeic keratosis
0.959 0.041 0.000
I60-I69 Cerebrovascular diseases
0.958 0.042 0.000
M15-M19 Arthrosis
0.957 0.043 0.000
N05.9 Unspecified
0.957 0.043 0.000
G51 Facial nerve disorders
0.956 0.044 0.000
E07 Other disorders of thyroid
0.956 0.044 0.000
D06 Carcinoma in situ of cervix uteri
0.955 0.045 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.954 0.046 0.000
M18 Arthrosis of first carpometacarpal joint
0.952 0.048 0.000
N18.4 Chronic kidney disease, stage 4
0.948 0.052 0.000
M24.1 Other articular cartilage disorders
0.948 0.052 0.000
H43-H45 Disorders of vitreous body and globe
0.947 0.053 0.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.053 0.947
M20.1 Hallux valgus (acquired)
0.000 0.053 0.947
K75.4 Autoimmune hepatitis
0.946 0.054 0.000
D68 Other coagulation defects
0.945 0.055 0.000
K75 Other inflammatory liver diseases
0.944 0.056 0.000
H34.8 Other retinal vascular occlusions
0.943 0.057 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.943 0.057 0.000
I20-I25 Ischaemic heart diseases
0.943 0.057 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.940 0.060 0.000
K70-K77 Diseases of liver
0.940 0.060 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.940 0.060 0.000
C81.1 Nodular sclerosis
0.938 0.062 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.938 0.062 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.062 0.938
N05.1 Focal and segmental glomerular lesions
0.938 0.062 0.000
I63 Cerebral infarction
0.938 0.062 0.000
D50.8 Other iron deficiency anaemias
0.937 0.063 0.000
I24 Other acute ischaemic heart diseases
0.937 0.063 0.000
Chapter XI Diseases of the digestive system
0.937 0.063 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.936 0.064 0.000
D06.9 Cervix, unspecified
0.935 0.065 0.000
G54 Nerve root and plexus disorders
0.935 0.065 0.000
H43 Disorders of vitreous body
0.933 0.067 0.000
I24.8 Other forms of acute ischaemic heart disease
0.933 0.067 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.933 0.067 0.000
E14.9 Without complications
0.932 0.068 0.000
E28 Ovarian dysfunction
0.932 0.068 0.000
H35 Other retinal disorders
0.931 0.069 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.072 0.928
H02 Other disorders of eyelid
0.927 0.073 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.926 0.074 0.000
D61 Other aplastic anaemias
0.926 0.074 0.000
N18.3 Chronic kidney disease, stage 3
0.923 0.077 0.000
D03 Melanoma in situ
0.921 0.079 0.000
G51.0 Bell's palsy
0.921 0.079 0.000
C91 Lymphoid leukaemia
0.920 0.080 0.000
E07.9 Disorder of thyroid, unspecified
0.919 0.081 0.000
E70-E90 Metabolic disorders
0.918 0.081 0.000
D04.5 Skin of trunk
0.916 0.084 0.000
E06 Thyroiditis
0.913 0.087 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.913 0.087 0.000
D69.4 Other primary thrombocytopenia
0.912 0.088 0.000
M35.7 Hypermobility syndrome
0.911 0.089 0.000
L10-L14 Bullous disorders
0.909 0.090 0.001
Q60-Q64 Congenital malformations of the urinary system
0.910 0.090 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.910 0.090 0.000
M07.3 Other psoriatic arthropathies
0.000 0.090 0.910
H43.8 Other disorders of vitreous body
0.909 0.091 0.000
M34 Systemic sclerosis
0.908 0.092 0.000
E89.0 Postprocedural hypothyroidism
0.908 0.092 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.908 0.092 0.000
D86.0 Sarcoidosis of lung
0.907 0.093 0.000
L92.0 Granuloma annulare
0.907 0.093 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.093 0.907
H33 Retinal detachments and breaks
0.907 0.093 0.000
I22 Subsequent myocardial infarction
0.906 0.094 0.000
E11.2 With renal complications
0.902 0.098 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.901 0.099 0.000
H50.0 Convergent concomitant strabismus
0.901 0.099 0.000
I12.9 Hypertensive renal disease without renal failure
0.900 0.100 0.000
Chapter XX External causes of morbidity and mortality
0.900 0.100 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.899 0.101 0.000
K90-K93 Other diseases of the digestive system
0.898 0.102 0.000
K90 Intestinal malabsorption
0.898 0.102 0.000
N04.1 Focal and segmental glomerular lesions
0.896 0.104 0.000
K90.9 Intestinal malabsorption, unspecified
0.896 0.104 0.000
K75.8 Other specified inflammatory liver diseases
0.895 0.105 0.000
M15 Polyarthrosis
0.893 0.107 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.108 0.892
H02.5 Other disorders affecting eyelid function
0.890 0.110 0.000
E10.0 With coma
0.886 0.114 0.000
I74.5 Embolism and thrombosis of iliac artery
0.885 0.115 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.884 0.116 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.883 0.117 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.883 0.117 0.000
N17 Acute renal failure
0.882 0.118 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.119 0.881
L94 Other localised connective tissue disorders
0.880 0.120 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.879 0.121 0.000
N04.2 Diffuse membranous glomerulonephritis
0.878 0.122 0.000
C83.7 Burkitt's tumour
0.877 0.123 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.876 0.124 0.000
D61.9 Aplastic anaemia, unspecified
0.872 0.128 0.000
L40.9 Psoriasis, unspecified
0.000 0.129 0.871
W20-W49 Exposure to inanimate mechanical forces
0.869 0.131 0.000
K73 Chronic hepatitis, not elsewhere classified
0.867 0.133 0.000
D68.8 Other specified coagulation defects
0.866 0.134 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.136 0.864
H50.5 Heterophoria
0.862 0.138 0.000
E14.8 With unspecified complications
0.862 0.138 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.860 0.140 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.141 0.859
I77.6 Arteritis, unspecified
0.859 0.141 0.000
L83 Acanthosis nigricans
0.855 0.145 0.000
M32 Systemic lupus erythematosus
0.855 0.145 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.854 0.146 0.000
E24 Cushing's syndrome
0.852 0.148 0.000
G70-G73 Diseases of myoneural junction and muscle
0.852 0.148 0.000
L13 Other bullous disorders
0.851 0.148 0.001
E27.2 Addisonian crisis
0.851 0.149 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.851 0.149 0.000
E03.8 Other specified hypothyroidism
0.849 0.151 0.000
E06.3 Autoimmune thyroiditis
0.848 0.152 0.000
H35.2 Other proliferative retinopathy
0.848 0.152 0.000
M60-M63 Disorders of muscles
0.846 0.154 0.000
E20 Hypoparathyroidism
0.846 0.154 0.000
D64.8 Other specified anaemias
0.843 0.157 0.000
H02.6 Xanthelasma of eyelid
0.842 0.158 0.000
C91.1 Chronic lymphocytic leukaemia
0.842 0.158 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.841 0.159 0.000
H35.4 Peripheral retinal degeneration
0.841 0.159 0.000
G54.6 Phantom limb syndrome with pain
0.838 0.162 0.000
G50 Disorders of trigeminal nerve
0.836 0.164 0.000
E21.0 Primary hyperparathyroidism
0.835 0.165 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.835 0.165 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.833 0.167 0.000
E50-E64 Other nutritional deficiencies
0.832 0.168 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.169 0.831
I74.8 Embolism and thrombosis of other arteries
0.830 0.170 0.000
G58 Other mononeuropathies
0.829 0.171 0.000
H49 Paralytic strabismus
0.828 0.172 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.828 0.172 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.827 0.173 0.000
E10.5 With peripheral circulatory complications
0.826 0.174 0.000
D68.2 Hereditary deficiency of other clotting factors
0.826 0.174 0.000
E28.2 Polycystic ovarian syndrome
0.825 0.175 0.000
H35.0 Background retinopathy and retinal vascular changes
0.825 0.175 0.000
D50.1 Sideropenic dysphagia
0.824 0.176 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.824 0.176 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.177 0.823
H25-H28 Disorders of lens
0.823 0.177 0.000
N18.5 Chronic kidney disease, stage 5
0.822 0.178 0.000
H33.0 Retinal detachment with retinal break
0.822 0.178 0.000
H33.1 Retinoschisis and retinal cysts
0.822 0.178 0.000
K72 Hepatic failure, not elsewhere classified
0.819 0.181 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.819 0.181 0.000
Q61 Cystic kidney disease
0.819 0.181 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.819 0.181 0.000
D69.9 Haemorrhagic condition, unspecified
0.818 0.182 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.818 0.182 0.000
I77.1 Stricture of artery
0.817 0.183 0.000
D04.7 Skin of lower limb, including hip
0.816 0.184 0.000
C88 Malignant immunoproliferative diseases
0.816 0.184 0.000
H02.0 Entropion and trichiasis of eyelid
0.815 0.185 0.000
E31 Polyglandular dysfunction
0.814 0.186 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.813 0.187 0.000
E28.3 Primary ovarian failure
0.811 0.189 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.811 0.189 0.000
E11.7 With multiple complications
0.810 0.190 0.000
H50.9 Strabismus, unspecified
0.810 0.190 0.000
L13.0 Dermatitis herpetiformis
0.809 0.191 0.000
H05 Disorders of orbit
0.809 0.191 0.000
H33.4 Traction detachment of retina
0.809 0.191 0.000
C83.0 Small cell (diffuse)
0.808 0.192 0.000
N05.8 Other
0.808 0.192 0.000
K50-K52 Noninfective enteritis and colitis
0.807 0.193 0.000
D68.6 Other Thrombophilia
0.806 0.193 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.806 0.194 0.000
E14.4 With neurological complications
0.804 0.196 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.804 0.196 0.000
D80 Immunodeficiency with predominantly antibody defects
0.804 0.196 0.000
D04.4 Skin of scalp and neck
0.803 0.197 0.000
H35.8 Other specified retinal disorders
0.803 0.197 0.000
D52 Folate deficiency anaemia
0.802 0.198 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.802 0.198 0.000
D04.6 Skin of upper limb, including shoulder
0.802 0.198 0.000
I77.2 Rupture of artery
0.801 0.199 0.000
E14.5 With peripheral circulatory complications
0.801 0.199 0.000
K52 Other non-infective gastro-enteritis and colitis
0.800 0.199 0.000
D86.3 Sarcoidosis of skin
0.799 0.201 0.000
G59.0 Diabetic mononeuropathy
0.799 0.201 0.000
C04 Malignant neoplasm of floor of mouth
0.799 0.201 0.000
Chapter I Certain infectious and parasitic diseases
0.799 0.201 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.201 0.799
N17.9 Acute renal failure, unspecified
0.798 0.202 0.000
N18.1 Chronic kidney disease, stage 1
0.798 0.202 0.000
E10.7 With multiple complications
0.797 0.203 0.000
N18.0 End-stage renal disease
0.796 0.204 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.206 0.794
V40-V49 Car occupant injured in transport accident
0.793 0.207 0.000
H50.2 Vertical strabismus
0.792 0.208 0.000
I71 Aortic aneurysm and dissection
0.792 0.208 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.791 0.209 0.000
L93 Lupus erythematosus
0.791 0.209 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.790 0.210 0.000
D69.8 Other specified haemorrhagic conditions
0.788 0.212 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.786 0.213 0.001
G72 Other myopathies
0.787 0.213 0.000
E14.1 With ketoacidosis
0.786 0.214 0.000
M33 Dermatopolymyositis
0.786 0.214 0.000
N03 Chronic nephritic syndrome
0.786 0.214 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.786 0.214 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.785 0.215 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.785 0.215 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.783 0.217 0.000
E14.2 Withrenal complications
0.781 0.219 0.000
L40 Psoriasis
0.028 0.220 0.753
D04.9 Skin, unspecified
0.780 0.220 0.000
H50.6 Mechanical strabismus
0.778 0.222 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.778 0.222 0.000
H26 Other cataract
0.777 0.223 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.777 0.223 0.000
C91.9 Lymphoid leukaemia, unspecified
0.776 0.224 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.224 0.776
L94.0 Localised scleroderma [morphea]
0.776 0.224 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.776 0.224 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.774 0.226 0.000
Q43 Other congenital malformations of intestine
0.773 0.227 0.000
D86.9 Sarcoidosis, unspecified
0.772 0.228 0.000
C85.1 B-cell lymphoma, unspecified
0.772 0.228 0.000
H43.1 Vitreous haemorrhage
0.771 0.229 0.000
D68.0 Von Willebrand's disease
0.771 0.229 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.232 0.768
A63.0 Anogenital (venereal) warts
0.767 0.233 0.000
M22 Disorders of patella
0.765 0.235 0.000
G51.3 Clonic hemifacial spasm
0.765 0.235 0.000
M24.9 Joint derangement, unspecified
0.765 0.235 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.764 0.236 0.000
D55-D59 Haemolytic anaemias
0.764 0.236 0.000
H26.9 Cataract, unspecified
0.764 0.236 0.000
E11.1 With ketoacidosis
0.762 0.238 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.760 0.239 0.000
E11.0 With coma
0.760 0.240 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.760 0.240 0.000
C07 Malignant neoplasm of parotid gland
0.760 0.240 0.000
E53 Deficiency of other B group vitamins
0.760 0.240 0.000
C95 Leukaemia of unspecified cell type
0.759 0.241 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.759 0.241 0.000
D04.2 Skin of ear and external auricular canal
0.759 0.241 0.000
W22 Striking against or struck by other objects
0.759 0.241 0.000
C83.1 Small cleaved cell (diffuse)
0.757 0.243 0.000
N04.0 Minor glomerular abnormality
0.756 0.243 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.756 0.244 0.000
E16.1 Other hypoglycaemia
0.755 0.245 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.754 0.245 0.000
M34.1 CR(E)ST syndrome
0.754 0.246 0.000
I11 Hypertensive heart disease
0.753 0.247 0.000
E73 Lactose intolerance
0.752 0.248 0.000
I73 Other peripheral vascular diseases
0.752 0.248 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.752 0.248 0.000
G51.9 Disorder of facial nerve, unspecified
0.752 0.248 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.250 0.750
L94.9 Localised connective tissue disorder, unspecified
0.749 0.251 0.000
H43.9 Disorder of vitreous body, unspecified
0.749 0.251 0.000
Q80-Q89 Other congenital malformations
0.749 0.251 0.000
I77.8 Other specified disorders of arteries and arterioles
0.749 0.251 0.000
C81.0 Lymphocytic predominance
0.748 0.252 0.000
E21.2 Other hyperparathyroidism
0.748 0.252 0.000
I63.8 Other cerebral infarction
0.748 0.252 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.253 0.746
K72.0 Acute and subacute hepatic failure
0.746 0.254 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.745 0.255 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.745 0.255 0.000
D69.2 Other nonthrombocytopenic purpura
0.744 0.256 0.000
V10-V19 Pedal cyclist injured in transport accident
0.744 0.256 0.000
D04.3 Skin of other and unspecified parts of face
0.744 0.256 0.000
D86.8 Sarcoidosis of other and combined sites
0.744 0.256 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.257 0.743
N02 Recurrent and persistent haematuria
0.743 0.257 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.743 0.257 0.000
H02.1 Ectropion of eyelid
0.742 0.258 0.000
G56.4 Causalgia
0.741 0.259 0.000
W20 Struck by thrown, projected or falling object
0.739 0.261 0.000
B07 Viral warts
0.738 0.262 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.737 0.263 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.736 0.264 0.000
E20.9 Hypoparathyroidism, unspecified
0.735 0.265 0.000
V20-V29 Motorcycle rider injured in transport accident
0.735 0.265 0.000
G56.8 Other mononeuropathies of upper limb
0.734 0.266 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.734 0.266 0.000
H50.4 Other and unspecified heterotropia
0.734 0.266 0.000
Q63 Other congenital malformations of kidney
0.734 0.266 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.734 0.266 0.000
W50-W64 Exposure to animate mechanical forces
0.734 0.266 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.733 0.267 0.000
E27.9 Disorder of adrenal gland, unspecified
0.732 0.268 0.000
H30 Chorioretinal inflammation
0.732 0.268 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.731 0.269 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.731 0.269 0.000
H50.8 Other specified strabismus
0.731 0.269 0.000
I77.0 Arteriovenous fistula, acquired
0.730 0.270 0.000
D03.4 Melanoma in situ of scalp and neck
0.730 0.270 0.000
I24.1 Dressler's syndrome
0.729 0.271 0.000
Q61.3 Polycystic kidney, unspecified
0.729 0.271 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.728 0.272 0.000
E89.4 Postprocedural ovarian failure
0.728 0.272 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.272 0.728
G50.0 Trigeminal neuralgia
0.727 0.273 0.000
L95.8 Other vasculitis limited to skin
0.727 0.273 0.000
H05.2 Exophthalmic conditions
0.726 0.274 0.000
H43.2 Crystalline deposits in vitreous body
0.726 0.274 0.000
M34.0 Progressive systemic sclerosis
0.726 0.274 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.726 0.274 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.725 0.275 0.000
H02.2 Lagophthalmos
0.725 0.275 0.000
Y52 Agents primarily affecting the cardiovascular system
0.725 0.275 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.725 0.275 0.000
L40.5 Arthropathic psoriasis
0.001 0.276 0.723
M34.9 Systemic sclerosis, unspecified
0.724 0.276 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.724 0.276 0.000
D09 Carcinoma in situ of other and unspecified sites
0.724 0.276 0.000
L12 Pemphigoid
0.723 0.276 0.001
E07.8 Other specified disorders of thyroid
0.724 0.276 0.000
H00.1 Chalazion
0.000 0.276 0.723
N18.2 Chronic kidney disease, stage 2
0.723 0.277 0.000
M60 Myositis
0.723 0.277 0.000
E05.8 Other thyrotoxicosis
0.722 0.278 0.000
K90.8 Other intestinal malabsorption
0.721 0.279 0.000
E53.8 Deficiency of other specified B group vitamins
0.720 0.280 0.000
G58.9 Mononeuropathy, unspecified
0.720 0.280 0.000
D68.5 Primary Thrombophilia
0.719 0.281 0.000
K71 Toxic liver disease
0.719 0.281 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.717 0.282 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E25 Adrenogenital disorders
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.717 0.283 0.000
N06 Isolated proteinuria with specified morphological lesion
0.717 0.283 0.000
N01 Rapidly progressive nephritic syndrome
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
D67 Hereditary factor IX deficiency
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
E27.5 Adrenomedullary hyperfunction
0.717 0.283 0.000
E27.0 Other adrenocortical overactivity
0.717 0.283 0.000
D69.1 Qualitative platelet defects
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
N00 Acute nephritic syndrome
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.001 0.283 0.716
M08 Juvenile arthritis
0.001 0.283 0.716
N05.6 Dense deposit disease
0.717 0.283 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.717 0.283 0.000
N05.0 Minor glomerular abnormality
0.717 0.283 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.716
M05.1 Rheumatoid lung disease
0.000 0.283 0.716
M05.0 Felty's syndrome
0.000 0.283 0.716
Q39 Congenital malformations of oesophagus
0.716 0.284 0.000
N04.8 Other
0.716 0.284 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.716 0.284 0.000
N04.6 Dense deposit disease
0.716 0.284 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.716 0.284 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.716 0.284 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.716 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.716 0.284 0.000
H06.3 Other disorders of orbit in diseases classified elsewhere
0.716 0.284 0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.716 0.284 0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.716 0.284 0.000
C04.9 Floor of mouth, unspecified
0.716 0.284 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.715 0.285 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.715 0.285 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.715 0.285 0.000
E16.4 Abnormal secretion of gastrin
0.715 0.285 0.000
E16.3 Increased secretion of glucagon
0.715 0.285 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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