TreeWAS – Variant ID: rs9296009

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
J33 Nasal polyp	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
M35.3 Polymyalgia rheumatica	1.000	0.000	0.000
J40-J47 Chronic lower respiratory diseases	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
J45 Asthma	1.000	0.000	0.000
J30-J39 Other diseases of upper respiratory tract	1.000	0.000	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	1.000	0.000	0.000
J33.9 Nasal polyp, unspecified	1.000	0.000	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E03 Other hypothyroidism	0.999	0.001	0.000
J33.0 Polyp of nasal cavity	0.999	0.001	0.000
E00-E07 Disorders of thyroid gland	0.999	0.001	0.000
# Top node	0.999	0.001	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.999	0.001	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.997	0.003	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.996	0.004	0.000
M65-M68 Disorders of synovium and tendon	0.992	0.008	0.000
M06.3 Rheumatoid nodule	0.991	0.009	0.000
M31 Other necrotising vasculopathies	0.990	0.010	0.000
J32 Chronic sinusitis	0.989	0.011	0.000
E10.9 Without complications	0.989	0.011	0.000
E10.1 With ketoacidosis	0.987	0.013	0.000
E10.3 With ophthalmic complications	0.984	0.016	0.000
M65 Synovitis and tenosynovitis	0.984	0.016	0.000
M31.6 Other giant cell arteritis	0.982	0.018	0.000
J32.9 Chronic sinusitis, unspecified	0.982	0.018	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.982	0.018	0.000
J47 Bronchiectasis	0.976	0.024	0.000
J20-J22 Other acute lower respiratory infections	0.975	0.025	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.975	0.025	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.975	0.025	0.000
M06.0 Seronegative rheumatoid arthritis	0.971	0.029	0.000
E10.4 With neurological complications	0.967	0.033	0.000
M20 Acquired deformities of fingers and toes	0.962	0.038	0.000
J22 Unspecified acute lower respiratory infection	0.960	0.040	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.959	0.041	0.000
J33.8 Other polyp of sinus	0.959	0.041	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.953	0.047	0.000
M06.34 Rheumatoid nodule (Hand)	0.951	0.049	0.000
M20.1 Hallux valgus (acquired)	0.947	0.053	0.000
Chapter XX External causes of morbidity and mortality	0.946	0.054	0.000
E10.5 With peripheral circulatory complications	0.946	0.054	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.941	0.059	0.000
Q28 Other congenital malformations of circulatory system	0.939	0.061	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.937	0.063	0.000
G35 Multiple sclerosis	0.000	0.063	0.937
M30 Polyarteritis nodosa and related conditions	0.937	0.063	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.936	0.064	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.933	0.067	0.000
E06 Thyroiditis	0.930	0.070	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.927	0.073	0.000
E10.8 With unspecified complications	0.925	0.075	0.000
M06.4 Inflammatory polyarthropathy	0.917	0.083	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.916	0.084	0.000
M80-M85 Disorders of bone density and structure	0.912	0.088	0.000
M95.0 Acquired deformity of nose	0.905	0.095	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.904	0.096	0.000
Q80-Q89 Other congenital malformations	0.904	0.096	0.000
X60-X84 Intentional self-harm	0.902	0.098	0.000
J32.2 Chronic ethmoidal sinusitis	0.901	0.099	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.901	0.099	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.895	0.105	0.000
E06.3 Autoimmune thyroiditis	0.894	0.106	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.891	0.109	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.890	0.110	0.000
M45-M49 Spondylopathies	0.885	0.115	0.000
Chapter VIII Diseases of the ear and mastoid process	0.884	0.116	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.881	0.119	0.000
M85 Other disorders of bone density and structure	0.881	0.119	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.879	0.121	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.879	0.121	0.000
Q50-Q56 Congenital malformations of genital organs	0.876	0.124	0.000
Q24 Other congenital malformations of heart	0.873	0.127	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.872	0.128	0.000
M45 Ankylosing spondylitis	0.872	0.128	0.000
J42 Unspecified chronic bronchitis	0.865	0.135	0.000
J09-J18 Influenza and pneumonia	0.864	0.136	0.000
H60-H62 Diseases of external ear	0.860	0.140	0.000
M86-M90 Other osteopathies	0.858	0.142	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.854	0.146	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.853	0.147	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.850	0.150	0.000
H60 Otitis externa	0.848	0.152	0.000
M85.8 Other specified disorders of bone density and structure	0.848	0.152	0.000
J46 Status asthmaticus	0.847	0.153	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.844	0.156	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.841	0.159	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.839	0.161	0.000
E10.6 With other specified complications	0.839	0.161	0.000
E10.2 With renal complications	0.838	0.162	0.000
Y52 Agents primarily affecting the cardiovascular system	0.837	0.163	0.000
Q83 Congenital malformations of breast	0.836	0.164	0.000
J35 Chronic diseases of tonsils and adenoids	0.835	0.165	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.834	0.166	0.000
M00-M03 Infectious arthropathies	0.832	0.168	0.000
J85 Abscess of lung and mediastinum	0.830	0.170	0.000
Q25 Congenital malformations of great arteries	0.828	0.172	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.826	0.174	0.000
M35.7 Hypermobility syndrome	0.824	0.176	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.824	0.176	0.000
M35.1 Other overlap syndromes	0.824	0.176	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.824	0.176	0.000
M12 Other specific arthropathies	0.822	0.178	0.000
J84 Other interstitial pulmonary diseases	0.817	0.183	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.817	0.183	0.000
M86 Osteomyelitis	0.813	0.187	0.000
M14 Arthropathies in other diseases classified elsewhere	0.812	0.188	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.810	0.190	0.000
E10.0 With coma	0.808	0.192	0.000
M05.8 Other seropositive rheumatoid arthritis	0.808	0.192	0.000
Q35-Q37 Cleft lip and cleft palate	0.806	0.194	0.000
J32.4 Chronic pansinusitis	0.802	0.198	0.000
M35.2 Behcet's disease	0.802	0.198	0.000
M06.8 Other specified rheumatoid arthritis	0.797	0.203	0.000
M05.1 Rheumatoid lung disease	0.795	0.204	0.000
H60.8 Other otitis externa	0.795	0.205	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.794	0.206	0.000
Q53 Undescended testicle	0.792	0.208	0.000
Y00-Y09 Assault	0.787	0.213	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.787	0.213	0.000
M40-M43 Deforming dorsopathies	0.784	0.216	0.000
M91-M94 Chondropathies	0.782	0.218	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.781	0.219	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.779	0.221	0.000
H60.9 Otitis externa, unspecified	0.778	0.222	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.777	0.223	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.774	0.226	0.000
Q24.5 Malformation of coronary vessels	0.772	0.228	0.000
M08 Juvenile arthritis	0.770	0.230	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.769	0.231	0.000
J45.8 Mixed asthma	0.768	0.232	0.000
E10.7 With multiple complications	0.768	0.232	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.767	0.233	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.767	0.233	0.000
E40-E46 Malnutrition	0.766	0.234	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.763	0.237	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.758	0.241	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.756	0.244	0.000
M86.9 Osteomyelitis, unspecified	0.756	0.244	0.000
V95-V97 Air and space transport accidents	0.754	0.246	0.000
M65.8 Other synovitis and tenosynovitis	0.752	0.248	0.000
M21 Other acquired deformities of limbs	0.750	0.250	0.000
M11 Other crystal arthropathies	0.749	0.251	0.000
M31.9 Necrotising vasculopathy, unspecified	0.749	0.251	0.000
J32.3 Chronic sphenoidal sinusitis	0.749	0.251	0.000
M67 Other disorders of synovium and tendon	0.748	0.252	0.000
J85.1 Abscess of lung with pneumonia	0.748	0.252	0.000
M31.1 Thrombotic microangiopathy	0.747	0.253	0.000
K90 Intestinal malabsorption	0.000	0.254	0.746
Y40 Systemic antibiotics	0.746	0.254	0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.745	0.255	0.000
M66 Spontaneous rupture of synovium and tendon	0.745	0.255	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.745	0.255	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.744	0.256	0.000
J33.1 Polypoid sinus degeneration	0.743	0.257	0.000
Q83.1 Accessory breast	0.741	0.259	0.000
J45.1 Nonallergic asthma	0.741	0.259	0.000
H60.1 Cellulitis of external ear	0.740	0.260	0.000
E03.1 Congenital hypothyroidism without goitre	0.739	0.261	0.000
X78 Intentional self-harm by sharp object	0.738	0.262	0.000
M31.3 Wegener's granulomatosis	0.738	0.262	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.736	0.264	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.736	0.264	0.000
M99 Biomechanical lesions, not elsewhere classified	0.735	0.265	0.000
Y71 Cardiovascular devices associated with adverse incidents	0.732	0.267	0.000
Q53.1 Undescended testicle, unilateral	0.732	0.268	0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.730	0.269	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.729	0.271	0.000
M30.0 Polyarteritis nodosa	0.728	0.272	0.000
Y58 Bacterial vaccines	0.727	0.273	0.000
X84 Intentional self-harm by unspecified means	0.726	0.274	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.726	0.274	0.000
J41 Simple and mucopurulent chronic bronchitis	0.725	0.275	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.725	0.275	0.000
M20.5 Other deformities of toe(s) (acquired)	0.725	0.275	0.000
M95.3 Acquired deformity of neck	0.724	0.276	0.000
Q12 Congenital lens malformations	0.724	0.276	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.721	0.279	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.719	0.281	0.000
W75-W84 Other accidental threats to breathing	0.717	0.283	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.717	0.283	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.2 Rheumatoid vasculitis	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E03.5 Myxoedema coma	0.716	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.716	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.716	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.716	0.284	0.000
E00 Congenital iodine-deficiency syndrome	0.716	0.284	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284	0.000
E11 Non-insulin-dependent diabetes mellitus	0.716	0.284	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.715	0.285	0.000
M00 Pyogenic arthritis	0.715	0.285	0.000
E06.5 Other chronic thyroiditis	0.714	0.286	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.714	0.286	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.711	0.289	0.000
Q78 Other osteochondrodysplasias	0.711	0.289	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.710	0.289	0.000
M06.38 Rheumatoid nodule (Other)	0.710	0.289	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.710	0.289	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.710	0.289	0.000
M06.33 Rheumatoid nodule (Forearm)	0.710	0.289	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.710	0.289	0.000
Q17 Other congenital malformations of ear	0.710	0.290	0.000
M31.8 Other specified necrotising vasculopathies	0.709	0.290	0.000
M31.7 Microscopic polyangiitis	0.709	0.290	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.709	0.290	0.000
M31.2 Lethal midline granuloma	0.709	0.290	0.000
M31.0 Hypersensitivity angiitis	0.709	0.290	0.000
M41 Scoliosis	0.709	0.291	0.000
M65.1 Other infective (teno)synovitis	0.708	0.292	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.707	0.293	0.000
V20-V29 Motorcycle rider injured in transport accident	0.707	0.293	0.000
Y82 Other and unspecified medical devices associated with adverse incidents	0.706	0.294	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.706	0.294	0.000
M65.2 Calcific tendinitis	0.705	0.294	0.000
M65.0 Abscess of tendon sheath	0.705	0.294	0.000
J35.1 Hypertrophy of tonsils	0.705	0.295	0.000
E07 Other disorders of thyroid	0.705	0.295	0.000
Q24.0 Dextrocardia	0.704	0.296	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.704	0.296	0.000
M35.8 Other specified systemic involvement of connective tissue	0.703	0.297	0.000
M89 Other disorders of bone	0.703	0.297	0.000
Q24.8 Other specified congenital malformations of heart	0.702	0.298	0.000
J17 Pneumonia in diseases classified elsewhere	0.702	0.298	0.000
Q54 Hypospadias	0.701	0.299	0.000
M49 Spondylopathies in diseases classified elsewhere	0.700	0.299	0.000
J21 Acute bronchiolitis	0.700	0.300	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.700	0.300	0.000
Q26 Congenital malformations of great veins	0.699	0.301	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.699	0.301	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.697	0.303	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.696	0.303	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.696	0.303	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.696	0.303	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.696	0.303	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.696	0.303	0.000
X00-X09 Exposure to smoke, fire and flames	0.696	0.304	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.691	0.309	0.000
Y10-Y34 Event of undetermined intent	0.691	0.309	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.691	0.309	0.000
Q66 Congenital deformities of feet	0.690	0.310	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.689	0.310	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.687	0.312	0.000
M82 Osteoporosis in diseases classified elsewhere	0.687	0.313	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.687	0.313	0.000
Y04 Assault by bodily force	0.686	0.314	0.000
H65-H75 Diseases of middle ear and mastoid	0.682	0.318	0.000
Y35-Y36 Legal intervention and operations of war	0.678	0.321	0.000
X85-X99 Assault	0.678	0.321	0.000
X30-X39 Exposure to forces of nature	0.678	0.321	0.000
W65-W74 Accidental drowning and submersion	0.678	0.321	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.678	0.321	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.678	0.321	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.678	0.322	0.000
E11.5 With peripheral circulatory complications	0.675	0.325	0.000
M85.2 Hyperostosis of skull	0.675	0.325	0.000
J37 Chronic laryngitis and laryngotracheitis	0.675	0.325	0.000
V90-V94 Water transport accidents	0.674	0.325	0.000
M80 Osteoporosis with pathological fracture	0.674	0.326	0.000
Q25.1 Coarctation of aorta	0.674	0.326	0.000
X65 Intentional self-poisoning by and exposure to alcohol	0.674	0.326	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.674	0.326	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.674	0.326	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.674	0.326	0.000
Q28.3 Other malformations of cerebral vessels	0.674	0.326	0.000
Q28.1 Other malformations of precerebral vessels	0.674	0.326	0.000
Q83.3 Accessory nipple	0.673	0.327	0.000
Y57 Other and unspecified drugs and medicaments	0.672	0.328	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.671	0.328	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.671	0.328	0.000
M30.2 Juvenile polyarteritis	0.671	0.328	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.671	0.329	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.671	0.329	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.670	0.330	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.670	0.330	0.000
X68 Intentional self-poisoning by and exposure to pesticides	0.669	0.330	0.000
M85.0 Fibrous dysplasia (monostotic)	0.669	0.331	0.000
J10 Influenza due to identified influenza virus	0.667	0.333	0.000
E14 Unspecified diabetes mellitus	0.667	0.333	0.000
E06.4 Drug-induced thyroiditis	0.667	0.333	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.667	0.333	0.000
E06.1 Subacute thyroiditis	0.667	0.333	0.000
E06.0 Acute thyroiditis	0.667	0.333	0.000
Q27 Other congenital malformations of peripheral vascular system	0.665	0.335	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.665	0.335	0.000
J35.2 Hypertrophy of adenoids	0.665	0.335	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.665	0.335	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.665	0.335	0.000
M95.5 Acquired deformity of pelvis	0.665	0.335	0.000
M95.1 Cauliflower ear	0.665	0.335	0.000
J20 Acute bronchitis	0.664	0.336	0.000
X10-X19 Contact with heat and hot substances	0.663	0.336	0.000
Q65 Congenital deformities of hip	0.663	0.337	0.000
Q83.8 Other congenital malformations of breast	0.662	0.338	0.000
J85.2 Abscess of lung without pneumonia	0.662	0.338	0.000
Q18 Other congenital malformations of face and neck	0.662	0.338	0.000
M86.6 Other chronic osteomyelitis	0.661	0.339	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.661	0.339	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.661	0.339	0.000
M41.9 Scoliosis, unspecified	0.660	0.340	0.000
Y77 Ophthalmic devices associated with adverse incidents	0.660	0.340	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.659	0.340	0.000
Y49.5 Other antipsychotics and neuroleptics	0.659	0.341	0.000
Q00-Q07 Congenital malformations of the nervous system	0.659	0.341	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.659	0.341	0.000
J85.0 Gangrene and necrosis of lung	0.658	0.342	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.658	0.342	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.658	0.342	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.658	0.342	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.658	0.342	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.658	0.342	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.658	0.342	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.658	0.342	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.658	0.342	0.000
J12 Viral pneumonia, not elsewhere classified	0.657	0.343	0.000
Q14 Congenital malformations of posterior segment of eye	0.657	0.343	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.656	0.344	0.000
M14.6 Neuropathic arthropathy	0.656	0.344	0.000
Q25.3 Stenosis of aorta	0.656	0.344	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.655	0.345	0.000
E03.8 Other specified hypothyroidism	0.655	0.345	0.000
Q55 Other congenital malformations of male genital organs	0.654	0.346	0.000
M95.4 Acquired deformity of chest and rib	0.654	0.346	0.000
M85.6 Other cyst of bone	0.654	0.346	0.000
M83 Adult osteomalacia	0.654	0.346	0.000
M12.2 Villonodular synovitis (pigmented)	0.653	0.347	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.653	0.347	0.000
Y71.2 Prosthetic and other implants, materials and accessory devices	0.653	0.347	0.000
J18 Pneumonia, organism unspecified	0.652	0.348	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.651	0.349	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.651	0.349	0.000
M66.2 Spontaneous rupture of extensor tendons	0.650	0.349	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.650	0.350	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.649	0.351	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.648	0.352	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.648	0.352	0.000
Q84 Other congenital malformations of integument	0.648	0.352	0.000
Q81 Epidermolysis bullosa	0.648	0.352	0.000
Q80 Congenital ichthyosis	0.648	0.352	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.648	0.352	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.648	0.352	0.000
V70-V79 Bus occupant injured in transport accident	0.647	0.352	0.000
X83 Intentional self-harm by other specified means	0.646	0.354	0.000
X82 Intentional self-harm by crashing of motor vehicle	0.646	0.354	0.000
X81 Intentional self-harm by jumping or lying before moving object	0.646	0.354	0.000
X80 Intentional self-harm by jumping from a high place	0.646	0.354	0.000
X79 Intentional self-harm by blunt object	0.646	0.354	0.000
X77 Intentional self-harm by steam, hot vapours and hot objects	0.646	0.354	0.000
X76 Intentional self-harm by smoke, fire and flames	0.646	0.354	0.000
X75 Intentional self-harm by explosive material	0.646	0.354	0.000
X74 Intentional self-harm by other and unspecified firearm discharge	0.646	0.354	0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.646	0.354	0.000
X72 Intentional self-harm by handgun discharge	0.646	0.354	0.000
X71 Intentional self-harm by drowning and submersion	0.646	0.354	0.000
X70 Intentional self-harm by hanging, strangulation and suffocation	0.646	0.354	0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.646	0.354	0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.646	0.354	0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.646	0.354	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.646	0.354	0.000
W50-W64 Exposure to animate mechanical forces	0.645	0.355	0.000
M12.3 Palindromic rheumatism	0.645	0.355	0.000
J11 Influenza, virus not identified	0.644	0.356	0.000
J31.0 Chronic rhinitis	0.644	0.356	0.000
Y42.5 Other oestrogens and progestogens	0.644	0.356	0.000
Q85 Phakomatoses, not elsewhere classified	0.643	0.357	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.642	0.358	0.000
Q15 Other congenital malformations of eye	0.642	0.358	0.000
Q13 Congenital malformations of anterior segment of eye	0.642	0.358	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.642	0.358	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.642	0.358	0.000
Y48 Anaesthetics and therapeutic gases	0.641	0.359	0.000
W94 Exposure to high and low air pressure and changes in air pressure	0.639	0.361	0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.639	0.361	0.000
Q25.4 Other congenital malformations of aorta	0.638	0.362	0.000
Y95 Nosocomial condition	0.637	0.363	0.000
J15.2 Pneumonia due to staphylococcus	0.636	0.364	0.000
V98-V99 Other and unspecified transport accidents	0.635	0.365	0.000
X60.8 Other specified place	0.634	0.366	0.000
Q35 Cleft palate	0.633	0.367	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.368	0.632
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.632	0.368	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.632	0.368	0.000
M85.5 Aneurysmal bone cyst	0.631	0.368	0.000
M85.4 Solitary bone cyst	0.631	0.368	0.000
M85.3 Osteitis condensans	0.631	0.368	0.000
M85.1 Skeletal fluorosis	0.631	0.368	0.000
W20-W49 Exposure to inanimate mechanical forces	0.631	0.369	0.000
J18.9 Pneumonia, unspecified	0.629	0.371	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.628	0.372	0.000
Q52 Other congenital malformations of female genitalia	0.628	0.372	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.628	0.372	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.627	0.373	0.000
Q24.6 Congenital heart block	0.626	0.374	0.000
Q24.4 Congenital subaortic stenosis	0.626	0.374	0.000
Q24.3 Pulmonary infundibular stenosis	0.626	0.374	0.000
Q24.2 Cor triatriatum	0.626	0.374	0.000
Q24.1 Levocardia	0.626	0.374	0.000
Y57.9 Drug or medicament, unspecified	0.626	0.374	0.000
Q75 Other congenital malformations of skull and face bones	0.625	0.374	0.000
Q73 Reduction defects of unspecified limb	0.625	0.374	0.000
Q72 Reduction defects of lower limb	0.625	0.374	0.000
Q71 Reduction defects of upper limb	0.625	0.374	0.000
Q70 Syndactyly	0.625	0.374	0.000
Q69 Polydactyly	0.625	0.374	0.000
Q68 Other congenital musculoskeletal deformities	0.625	0.374	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.625	0.375	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.625	0.375	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.625	0.375	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.625	0.375	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.625	0.375	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.625	0.375	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.625	0.375	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.625	0.375	0.000
M94 Other disorders of cartilage	0.625	0.375	0.000
H60.4 Cholesteatoma of external ear	0.625	0.375	0.000
Q37 Cleft palate with cleft lip	0.624	0.376	0.000
Y40.8 Other systemic antibiotics	0.623	0.377	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.377	0.623
M67.1 Other contracture of tendon (sheath)	0.623	0.377	0.000
X78.0 Home	0.622	0.378	0.000
H60.3 Other infective otitis externa	0.620	0.380	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.620	0.380	0.000
M20.3 Other deformity of hallux (acquired)	0.620	0.380	0.000
J09 Influenza due to certain identified influenza virus	0.619	0.381	0.000
Y40.3 Macrolides	0.617	0.383	0.000
M86.8 Other osteomyelitis	0.616	0.384	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.616	0.384	0.000
M32 Systemic lupus erythematosus	0.614	0.385	0.000
J31.1 Chronic nasopharyngitis	0.614	0.386	0.000
M14.2 Diabetic arthropathy	0.612	0.388	0.000
Y09 Assault by unspecified means	0.612	0.388	0.000
M85.9 Disorder of bone density and structure, unspecified	0.611	0.388	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.610	0.390	0.000
M00.9 Pyogenic arthritis, unspecified	0.610	0.390	0.000
H60.0 Abscess of external ear	0.609	0.390	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.609	0.391	0.000
V01-V09 Pedestrian injured in transport accident	0.608	0.392	0.000
H60.2 Malignant otitis externa	0.608	0.392	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.608	0.392	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.608	0.392	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.608	0.392	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.608	0.392	0.000
Y43 Primarily systemic agents	0.608	0.392	0.000
M21.6 Other acquired deformities of ankle and foot	0.608	0.392	0.000
V40-V49 Car occupant injured in transport accident	0.608	0.392	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.608	0.392	0.000
Y82.2 Prosthetic and other implants, materials and accessory devices	0.607	0.393	0.000
J40 Bronchitis, not specified as acute or chronic	0.607	0.393	0.000
M89.8 Other specified disorders of bone	0.607	0.393	0.000
M89.0 Algoneurodystrophy	0.606	0.393	0.000
M67.8 Other specified disorders of synovium and tendon	0.606	0.394	0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.606	0.394	0.000
J32.1 Chronic frontal sinusitis	0.605	0.394	0.000
Y81 General- and plastic-surgery devices associated with adverse incidents	0.605	0.395	0.000
Y80 Physical medicine devices associated with adverse incidents	0.605	0.395	0.000
Y78 Radiological devices associated with adverse incidents	0.605	0.395	0.000
Y75 Neurological devices associated with adverse incidents	0.605	0.395	0.000
Y74 General hospital and personal-use devices associated with adverse incidents	0.605	0.395	0.000
Y72 Otorhinolaryngological devices associated with adverse incidents	0.605	0.395	0.000
Y70 Anaesthesiology devices associated with adverse incidents	0.605	0.395	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.605	0.395	0.000
M08.0 Juvenile rheumatoid arthritis	0.605	0.395	0.000
Q10.0 Congenital ptosis	0.603	0.397	0.000
Y58.0 BCG vaccine	0.603	0.397	0.000
V97 Other specified air transport accidents	0.602	0.398	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.601	0.398	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.601	0.399	0.000
Q12.0 Congenital cataract	0.601	0.399	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.601	0.399	0.000
Q67.6 Pectus excavatum	0.601	0.399	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.600	0.399	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations