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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9310385
log Bayes Factor = 12.836
Chromosome 3   position 11,611,146  (GRCh37) Explore rs9310385 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
K22 Other diseases of oesophagus
0.998 0.002 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.997 0.003 0.000
M54 Dorsalgia
0.997 0.003 0.000
I84 Haemorrhoids
0.995 0.005 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.990 0.010 0.000
R50-R69 General symptoms and signs
0.990 0.010 0.000
K22.7 Barrett's oesophagus
0.988 0.012 0.000
Chapter VIII Diseases of the ear and mastoid process
0.987 0.013 0.000
Chapter IX Diseases of the circulatory system
0.986 0.014 0.000
I84.9 Unspecified haemorrhoids without complication
0.984 0.016 0.000
M20-M25 Other joint disorders
0.982 0.018 0.000
M51 Other intervertebral disk disorders
0.977 0.023 0.000
M45-M49 Spondylopathies
0.974 0.026 0.000
Chapter VI Diseases of the nervous system
0.974 0.026 0.000
H65-H75 Diseases of middle ear and mastoid
0.970 0.030 0.000
I84.2 Internal haemorrhoids without complication
0.966 0.034 0.000
K31 Other diseases of stomach and duodenum
0.966 0.034 0.000
M54.4 Lumbago with sciatica
0.958 0.042 0.000
M20 Acquired deformities of fingers and toes
0.956 0.044 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.949 0.051 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.948 0.052 0.000
M48 Other spondylopathies
0.945 0.055 0.000
M51.2 Other specified intervertebral disk displacement
0.943 0.057 0.000
R53 Malaise and fatigue
0.942 0.058 0.000
M54.1 Radiculopathy
0.939 0.061 0.000
R63 Symptoms and signs concerning food and fluid intake
0.939 0.061 0.000
K11 Diseases of salivary glands
0.939 0.061 0.000
K14 Diseases of tongue
0.937 0.063 0.000
Chapter VII Diseases of the eye and adnexa
0.937 0.063 0.000
K22.1 Ulcer of oesophagus
0.934 0.066 0.000
I84.8 Unspecified haemorrhoids with other complications
0.932 0.068 0.000
M40-M43 Deforming dorsopathies
0.927 0.073 0.000
K08 Other disorders of teeth and supporting structures
0.926 0.074 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.920 0.080 0.000
M48.0 Spinal stenosis
0.919 0.081 0.000
H30-H36 Disorders of choroid and retina
0.917 0.083 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.917 0.083 0.000
K70-K77 Diseases of liver
0.915 0.085 0.000
R94 Abnormal results of function studies
0.914 0.086 0.000
R21 Rash and other nonspecific skin eruption
0.911 0.089 0.000
K31.7 Polyp of stomach and duodenum
0.907 0.093 0.000
M48.06 Spinal stenosis (Lumbar region)
0.902 0.098 0.000
K22.4 Dyskinesia of oesophagus
0.901 0.099 0.000
K90-K93 Other diseases of the digestive system
0.900 0.100 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.898 0.102 0.000
R63.0 Anorexia
0.896 0.104 0.000
H74 Other disorders of middle ear and mastoid
0.896 0.104 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.895 0.105 0.000
M20.1 Hallux valgus (acquired)
0.891 0.109 0.000
M15-M19 Arthrosis
0.891 0.109 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.889 0.111 0.000
K14.8 Other diseases of tongue
0.885 0.115 0.000
K22.2 Oesophageal obstruction
0.882 0.118 0.000
R94.5 Abnormal results of liver function studies
0.876 0.124 0.000
M54.2 Cervicalgia
0.874 0.126 0.000
I81 Portal vein thrombosis
0.873 0.127 0.000
K90 Intestinal malabsorption
0.871 0.129 0.000
I84.5 External haemorrhoids without complication
0.867 0.133 0.000
H60-H62 Diseases of external ear
0.866 0.134 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.863 0.137 0.000
G90-G99 Other disorders of the nervous system
0.863 0.137 0.000
Chapter XX External causes of morbidity and mortality
0.862 0.138 0.000
H33 Retinal detachments and breaks
0.862 0.138 0.000
I84.4 External haemorrhoids with other complications
0.860 0.140 0.000
R02 Gangrene, not elsewhere classified
0.860 0.140 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.859 0.141 0.000
M20.2 Hallux rigidus
0.859 0.141 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.858 0.142 0.000
M05-M14 Inflammatory polyarthropathies
0.851 0.149 0.000
K90.0 Coeliac disease
0.848 0.152 0.000
K12 Stomatitis and related lesions
0.848 0.152 0.000
K09 Cysts of oral region, not elsewhere classified
0.847 0.153 0.000
H73 Other disorders of tympanic membrane
0.846 0.154 0.000
R60 Oedema, not elsewhere classified
0.842 0.158 0.000
R52 Pain, not elsewhere classified
0.841 0.159 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.838 0.162 0.000
H36 Retinal disorders in diseases classified elsewhere
0.836 0.164 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.831 0.169 0.000
R59 Enlarged lymph nodes
0.831 0.169 0.000
M54.3 Sciatica
0.829 0.171 0.000
I84.6 Residual haemorrhoidal skin tags
0.829 0.171 0.000
M35 Other systemic involvement of connective tissue
0.828 0.171 0.000
K11.2 Sialoadenitis
0.823 0.177 0.000
K22.5 Diverticulum of oesophagus, acquired
0.823 0.177 0.000
M41 Scoliosis
0.818 0.182 0.000
M54.16 Radiculopathy (Lumbar region)
0.816 0.184 0.000
M91-M94 Chondropathies
0.813 0.187 0.000
M20.0 Deformity of finger(s)
0.812 0.188 0.000
M54.12 Radiculopathy (Cervical region)
0.810 0.190 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.810 0.190 0.000
G30-G32 Other degenerative diseases of the nervous system
0.809 0.191 0.000
M25 Other joint disorders, not elsewhere classified
0.806 0.194 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.805 0.195 0.000
R05 Cough
0.804 0.196 0.000
R54 Senility
0.804 0.196 0.000
K26 Duodenal ulcer
0.801 0.199 0.000
M43 Other deforming dorsopathies
0.801 0.199 0.000
I86 Varicose veins of other sites
0.793 0.207 0.000
H66 Suppurative and unspecified otitis media
0.793 0.207 0.000
R50 Fever of unknown origin
0.793 0.207 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.792 0.208 0.000
M70-M79 Other soft tissue disorders
0.790 0.209 0.000
Q80-Q89 Other congenital malformations
0.790 0.209 0.000
M47 Spondylosis
0.789 0.211 0.000
K11.5 Sialolithiasis
0.786 0.214 0.000
K01 Embedded and impacted teeth
0.786 0.214 0.000
Y43 Primarily systemic agents
0.786 0.214 0.000
K75 Other inflammatory liver diseases
0.784 0.216 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.781 0.219 0.000
M80-M85 Disorders of bone density and structure
0.780 0.220 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.780 0.220 0.000
H33.3 Retinal breaks without detachment
0.779 0.221 0.000
H36.0 Diabetic retinopathy
0.778 0.222 0.000
G81 Hemiplegia
0.775 0.225 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.770 0.230 0.000
Y43.3 Other antineoplastic drugs
0.769 0.231 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.768 0.232 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.765 0.235 0.000
I82 Other venous embolism and thrombosis
0.764 0.236 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.764 0.236 0.000
H35 Other retinal disorders
0.763 0.237 0.000
M31 Other necrotising vasculopathies
0.762 0.238 0.000
H61 Other disorders of external ear
0.761 0.239 0.000
K74 Fibrosis and cirrhosis of liver
0.761 0.239 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.759 0.241 0.000
M54.19 Radiculopathy (Site unspecified)
0.759 0.241 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.758 0.242 0.000
M21 Other acquired deformities of limbs
0.758 0.242 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.757 0.242 0.000
H73.8 Other specified disorders of tympanic membrane
0.757 0.243 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.756 0.244 0.000
K12.3 Oral mucositis (ulcerative)
0.755 0.245 0.000
R52.2 Other chronic pain
0.753 0.247 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.753 0.247 0.000
M34 Systemic sclerosis
0.751 0.249 0.000
H69 Other disorders of Eustachian tube
0.750 0.250 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.749 0.251 0.000
M60-M63 Disorders of muscles
0.748 0.251 0.000
K08.3 Retained dental root
0.746 0.254 0.000
H71 Cholesteatoma of middle ear
0.746 0.254 0.000
M54.22 Cervicalgia (Cervical region)
0.746 0.254 0.000
G58 Other mononeuropathies
0.744 0.256 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.744 0.256 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.743 0.257 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.742 0.258 0.000
G82 Paraplegia and tetraplegia
0.742 0.258 0.000
R59.9 Enlarged lymph nodes, unspecified
0.742 0.258 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.741 0.258 0.000
K04 Diseases of pulp and periapical tissues
0.741 0.259 0.000
M41.9 Scoliosis, unspecified
0.740 0.260 0.000
H74.0 Tympanosclerosis
0.738 0.262 0.000
R63.4 Abnormal weight loss
0.738 0.262 0.000
K11.1 Hypertrophy of salivary gland
0.737 0.263 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.737 0.263 0.000
K14.0 Glossitis
0.735 0.265 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.735 0.265 0.000
I84.3 External thrombosed haemorrhoids
0.733 0.267 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.732 0.268 0.000
M54.9 Dorsalgia, unspecified
0.731 0.269 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.730 0.270 0.000
I84.1 Internal haemorrhoids with other complications
0.729 0.271 0.000
H90-H95 Other disorders of ear
0.728 0.272 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.727 0.273 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.727 0.273 0.000
D50-D53 Nutritional anaemias
0.727 0.273 0.000
M00-M03 Infectious arthropathies
0.726 0.274 0.000
I84.0 Internal thrombosed haemorrhoids
0.725 0.275 0.000
G51 Facial nerve disorders
0.724 0.276 0.000
M19 Other arthrosis
0.722 0.278 0.000
M35.3 Polymyalgia rheumatica
0.722 0.278 0.000
K11.8 Other diseases of salivary glands
0.722 0.278 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.721 0.279 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.721 0.279 0.000
G70-G73 Diseases of myoneural junction and muscle
0.720 0.279 0.000
M17 Gonarthrosis [arthrosis of knee]
0.720 0.280 0.000
M53 Other dorsopathies, not elsewhere classified
0.720 0.280 0.000
K09.8 Other cysts of oral region, not elsewhere classified
0.719 0.281 0.000
M47.8 Other spondylosis
0.719 0.281 0.000
M45 Ankylosing spondylitis
0.719 0.281 0.000
K70 Alcoholic liver disease
0.719 0.281 0.000
H72 Perforation of tympanic membrane
0.718 0.282 0.000
K07 Dentofacial anomalies [including malocclusion]
0.718 0.282 0.000
M20.3 Other deformity of hallux (acquired)
0.718 0.282 0.000
I85 Oesophageal varices
0.718 0.282 0.000
H53-H54 Visual disturbances and blindness
0.718 0.282 0.000
M13 Other arthritis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K28 Gastrojejunal ulcer
0.716 0.284 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
R94.3 Abnormal results of cardiovascular function studies
0.716 0.284 0.000
K22.3 Perforation of oesophagus
0.715 0.284 0.000
K03 Other diseases of hard tissues of teeth
0.715 0.285 0.000
K00 Disorders of tooth development and eruption
0.715 0.285 0.000
M54.8 Other dorsalgia
0.714 0.285 0.000
M54.6 Pain in thoracic spine
0.714 0.285 0.000
M54.0 Panniculitis affecting regions of neck and back
0.714 0.285 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.713 0.287 0.000
M51.8 Other specified intervertebral disk disorders
0.713 0.287 0.000
R68 Other general symptoms and signs
0.711 0.288 0.000
M43.1 Spondylolisthesis
0.710 0.290 0.000
I88 Nonspecific lymphadenitis
0.710 0.290 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.710 0.290 0.000
R62 Lack of expected normal physiological development
0.710 0.290 0.000
R57 Shock, not elsewhere classified
0.710 0.290 0.000
R64 Cachexia
0.710 0.290 0.000
R58 Haemorrhage, not elsewhere classified
0.710 0.290 0.000
D80-D89 Certain disorders involving the immune mechanism
0.709 0.291 0.000
M86-M90 Other osteopathies
0.708 0.291 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.708 0.292 0.000
I00-I02 Acute rheumatic fever
0.707 0.293 0.000
K22.0 Achalasia of cardia
0.706 0.294 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.706 0.294 0.000
H55-H59 Other disorders of eye and adnexa
0.706 0.294 0.000
Chapter X Diseases of the respiratory system
0.705 0.295 0.000
H65 Nonsuppurative otitis media
0.704 0.295 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.704 0.296 0.000
M33 Dermatopolymyositis
0.704 0.296 0.000
M32 Systemic lupus erythematosus
0.704 0.296 0.000
M30 Polyarteritis nodosa and related conditions
0.704 0.296 0.000
K73 Chronic hepatitis, not elsewhere classified
0.703 0.297 0.000
M54.29 Cervicalgia-Site unspe
0.703 0.297 0.000
H33.2 Serous retinal detachment
0.703 0.297 0.000
M54.36 Sciatica (Lumbar region)
0.702 0.298 0.000
H43-H45 Disorders of vitreous body and globe
0.701 0.299 0.000
M51.3 Other specified intervertebral disk degeneration
0.700 0.299 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.700 0.299 0.000
M51.9 Intervertebral disk disorder, unspecified
0.700 0.299 0.000
M51.4 Schmorl's nodes
0.700 0.299 0.000
R51 Headache
0.700 0.300 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.699 0.301 0.000
R94.4 Abnormal results of kidney function studies
0.699 0.301 0.000
M49 Spondylopathies in diseases classified elsewhere
0.699 0.301 0.000
G83 Other paralytic syndromes
0.698 0.302 0.000
J30-J39 Other diseases of upper respiratory tract
0.698 0.302 0.000
M17.0 Primary gonarthrosis, bilateral
0.697 0.303 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.696 0.304 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.695 0.305 0.000
H70 Mastoiditis and related conditions
0.695 0.305 0.000
H68 Eustachian salpingitis and obstruction
0.695 0.305 0.000
H67 Otitis media in diseases classified elsewhere
0.695 0.305 0.000
K65-K67 Diseases of peritoneum
0.695 0.305 0.000
K10 Other diseases of jaws
0.695 0.305 0.000
Chapter XXII Codes for special purposes
0.694 0.306 0.000
M46 Other inflammatory spondylopathies
0.694 0.306 0.000
K05 Gingivitis and periodontal diseases
0.694 0.306 0.000
M79.0 Rheumatism, unspecified
0.693 0.307 0.000
M06 Other rheumatoid arthritis
0.692 0.307 0.000
K31.6 Fistula of stomach and duodenum
0.692 0.308 0.000
K31.5 Obstruction of duodenum
0.692 0.308 0.000
K31.4 Gastric diverticulum
0.692 0.308 0.000
K31.3 Pylorospasm, not elsewhere classified
0.692 0.308 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.692 0.308 0.000
K31.0 Acute dilatation of stomach
0.692 0.308 0.000
M18 Arthrosis of first carpometacarpal joint
0.692 0.308 0.000
G81.9 Hemiplegia, unspecified
0.689 0.311 0.000
Q60-Q64 Congenital malformations of the urinary system
0.689 0.311 0.000
I87 Other disorders of veins
0.688 0.312 0.000
M05 Seropositive rheumatoid arthritis
0.687 0.313 0.000
M24 Other specific joint derangements
0.687 0.313 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.687 0.313 0.000
R60.0 Localised oedema
0.687 0.313 0.000
G50 Disorders of trigeminal nerve
0.687 0.313 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.686 0.313 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.686 0.313 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.686 0.313 0.000
M54.44 Lumbago with sciatica-Thoracic
0.686 0.313 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.686 0.313 0.000
M54.42 Lumbago with sciatica-Cervical
0.686 0.313 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.686 0.313 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.686 0.313 0.000
R03.1 Nonspecific low blood-pressure reading
0.686 0.314 0.000
R63.1 Polydipsia
0.686 0.314 0.000
Q50-Q56 Congenital malformations of genital organs
0.685 0.315 0.000
R17 Unspecified jaundice
0.683 0.317 0.000
R23 Other skin changes
0.683 0.317 0.000
H33.0 Retinal detachment with retinal break
0.682 0.318 0.000
G91 Hydrocephalus
0.681 0.319 0.000
D60-D64 Aplastic and other anaemias
0.681 0.319 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.679 0.320 0.000
M54.5 Low back pain
0.679 0.321 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.679 0.321 0.000
R60.9 Oedema, unspecified
0.678 0.322 0.000
K22.9 Disease of oesophagus, unspecified
0.678 0.322 0.000
M48.9 Spondylopathy, unspecified
0.678 0.322 0.000
M48.8 Other specified spondylopathies
0.678 0.322 0.000
M48.4 Fatigue fracture of vertebra
0.678 0.322 0.000
M48.3 Traumatic spondylopathy
0.678 0.322 0.000
M48.2 Kissing spine
0.678 0.322 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.678 0.322 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.677 0.323 0.000
M50 Cervical disk disorders
0.676 0.323 0.000
R20 Disturbances of skin sensation
0.674 0.326 0.000
M16 Coxarthrosis [arthrosis of hip]
0.674 0.326 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.674 0.326 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.674 0.326 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.674 0.326 0.000
M54.14 Radiculopathy (Thoracic region)
0.674 0.326 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.674 0.326 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.674 0.326 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.674 0.326 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.674 0.326 0.000
R63.5 Abnormal weight gain
0.674 0.326 0.000
R63.3 Feeding difficulties and mismanagement
0.674 0.326 0.000
R63.2 Polyphagia
0.674 0.326 0.000
K11.9 Disease of salivary gland, unspecified
0.673 0.327 0.000
K11.7 Disturbances of salivary secretion
0.673 0.327 0.000
K11.6 Mucocele of salivary gland
0.673 0.327 0.000
K11.4 Fistula of salivary gland
0.673 0.327 0.000
K11.3 Abscess of salivary gland
0.673 0.327 0.000
K11.0 Atrophy of salivary gland
0.673 0.327 0.000
K20 Oesophagitis
0.673 0.327 0.000
R50.8 Other specified fever
0.673 0.327 0.000
M47.82 Other spondylosis (Cervical region)
0.673 0.327 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.672 0.328 0.000
K14.6 Glossodynia
0.672 0.328 0.000
K14.5 Plicated tongue
0.672 0.328 0.000
K14.4 Atrophy of tongue papillae
0.672 0.328 0.000
K14.3 Hypertrophy of tongue papillae
0.672 0.328 0.000
K14.2 Median rhomboid glossitis
0.672 0.328 0.000
K14.1 Geographic tongue
0.672 0.328 0.000
W50-W64 Exposure to animate mechanical forces
0.668 0.332 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.668 0.332 0.000
Y86 Sequelae of other accidents
0.668 0.332 0.000
H10-H13 Disorders of conjunctiva
0.667 0.333 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.667 0.333 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.666 0.334 0.000
M42 Spinal osteochondrosis
0.665 0.335 0.000
M40 Kyphosis and lordosis
0.665 0.335 0.000
K26.4 Chronic or unspecified with haemorrhage
0.665 0.335 0.000
H60 Otitis externa
0.664 0.336 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.664 0.336 0.000
R56 Convulsions, not elsewhere classified
0.664 0.336 0.000
I74 Arterial embolism and thrombosis
0.662 0.338 0.000
M48.02 Spinal stenosis (Cervical region)
0.661 0.339 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.659 0.340 0.000
Q35-Q37 Cleft lip and cleft palate
0.659 0.340 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.659 0.340 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.659 0.340 0.000
Q00-Q07 Congenital malformations of the nervous system
0.659 0.340 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.659 0.341 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.659 0.341 0.000
M48.04 Spinal stenosis (Thoracic region)
0.659 0.341 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.659 0.341 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.659 0.341 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.659 0.341 0.000
G58.9 Mononeuropathy, unspecified
0.659 0.341 0.000
M92 Other juvenile osteochondrosis
0.658 0.342 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.658 0.342 0.000
H31 Other disorders of choroid
0.658 0.342 0.000
H30 Chorioretinal inflammation
0.658 0.342 0.000
D55-D59 Haemolytic anaemias
0.658 0.342 0.000
Chapter I Certain infectious and parasitic diseases
0.658 0.342 0.000
K77 Liver disorders in diseases classified elsewhere
0.656 0.344 0.000
K71 Toxic liver disease
0.656 0.344 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.655 0.345 0.000
R94.7 Abnormal results of other endocrine function studies
0.655 0.345 0.000
R94.6 Abnormal results of thyroid function studies
0.655 0.345 0.000
R94.2 Abnormal results of pulmonary function studies
0.655 0.345 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.655 0.345 0.000
R94.0 Abnormal results of function studies of central nervous system
0.655 0.345 0.000
H66.9 Otitis media, unspecified
0.655 0.345 0.000
M25.7 Osteophyte
0.655 0.345 0.000
K25 Gastric ulcer
0.654 0.346 0.000
X60-X84 Intentional self-harm
0.653 0.347 0.000
K14.9 Disease of tongue, unspecified
0.652 0.348 0.000
I86.1 Scrotal varices
0.652 0.348 0.000
J32 Chronic sinusitis
0.652 0.348 0.000
M19.0 Primary arthrosis of other joints
0.651 0.349 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.651 0.349 0.000
K90.9 Intestinal malabsorption, unspecified
0.650 0.350 0.000
K72 Hepatic failure, not elsewhere classified
0.647 0.353 0.000
K09.0 Developmental odontogenic cysts
0.646 0.354 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.646 0.354 0.000
Q85 Phakomatoses, not elsewhere classified
0.645 0.355 0.000
D75 Other diseases of blood and blood-forming organs
0.644 0.356 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.643 0.357 0.000
M65-M68 Disorders of synovium and tendon
0.642 0.358 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.642 0.358 0.000
H74.4 Polyp of middle ear
0.642 0.358 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.642 0.358 0.000
H74.1 Adhesive middle ear disease
0.642 0.358 0.000
G80 Infantile cerebral palsy
0.642 0.358 0.000
K31.8 Other specified diseases of stomach and duodenum
0.641 0.359 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.641 0.359 0.000
K75.8 Other specified inflammatory liver diseases
0.641 0.359 0.000
K75.4 Autoimmune hepatitis
0.640 0.360 0.000
M15 Polyarthrosis
0.639 0.361 0.000
K27 Peptic ulcer, site unspecified
0.638 0.362 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.636 0.364 0.000
R52.9 Pain, unspecified
0.635 0.365 0.000
M79.6 Pain in limb
0.635 0.365 0.000
M54.37 Sciatica (Lumbosacral region)
0.635 0.365 0.000
K01.1 Impacted teeth
0.635 0.365 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.634 0.366 0.000
R13 Dysphagia
0.634 0.366 0.000
W20-W49 Exposure to inanimate mechanical forces
0.633 0.367 0.000
H61.8 Other specified disorders of external ear
0.633 0.367 0.000
G93 Other disorders of brain
0.633 0.367 0.000
G82.2 Paraplegia, unspecified
0.632 0.367 0.000
G96 Other disorders of central nervous system
0.632 0.368 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.631 0.369 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.630 0.370 0.000
I70 Atherosclerosis
0.630 0.370 0.000
D70 Agranulocytosis
0.630 0.370 0.000
K92 Other diseases of digestive system
0.629 0.371 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.628 0.372 0.000
R01 Cardiac murmurs and other cardiac sounds
0.627 0.373 0.000
I82.2 Embolism and thrombosis of vena cava
0.627 0.373 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.626 0.373 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.626 0.373 0.000
M54.27 Cervicalgia-Lumbosacral
0.626 0.373 0.000
M54.26 Cervicalgia-Lumbar
0.626 0.373 0.000
M54.25 Cervicalgia-Thoracolumbar
0.626 0.373 0.000
M54.24 Cervicalgia-Thoracic
0.626 0.373 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.626 0.373 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.626 0.373 0.000
M54.20 Cervicalgia-Mult site
0.626 0.373 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.626 0.374 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.626 0.374 0.000
K74.0 Hepatic fibrosis
0.625 0.375 0.000
Y52 Agents primarily affecting the cardiovascular system
0.625 0.375 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.625 0.375 0.000
K90.8 Other intestinal malabsorption
0.625 0.375 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.625 0.375 0.000
K90.3 Pancreatic steatorrhoea
0.625 0.375 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.625 0.375 0.000
K90.1 Tropical sprue
0.625 0.375 0.000
H35.6 Retinal haemorrhage
0.624 0.376 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.622 0.377 0.000
H35.3 Degeneration of macula and posterior pole
0.621 0.379 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.621 0.379 0.000
H40-H42 Glaucoma
0.619 0.381 0.000
G54 Nerve root and plexus disorders
0.619 0.381 0.000
G52 Disorders of other cranial nerves
0.619 0.381 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.619 0.381 0.000
G90 Disorders of autonomic nervous system
0.619 0.381 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.619 0.381 0.000
G92 Toxic encephalopathy
0.619 0.381 0.000
Y35-Y36 Legal intervention and operations of war
0.618 0.382 0.000
Y10-Y34 Event of undetermined intent
0.618 0.382 0.000
Y00-Y09 Assault
0.618 0.382 0.000
X85-X99 Assault
0.618 0.382 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.618 0.382 0.000
X50-X57 Overexertion, travel and privation
0.618 0.382 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.618 0.382 0.000
X30-X39 Exposure to forces of nature
0.618 0.382 0.000
X20-X29 Contact with venomous animals and plants
0.618 0.382 0.000
X10-X19 Contact with heat and hot substances
0.618 0.382 0.000
X00-X09 Exposure to smoke, fire and flames
0.618 0.382 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.618 0.382 0.000
W75-W84 Other accidental threats to breathing
0.618 0.382 0.000
W65-W74 Accidental drowning and submersion
0.618 0.382 0.000
V98-V99 Other and unspecified transport accidents
0.618 0.382 0.000
V95-V97 Air and space transport accidents
0.618 0.382 0.000
V90-V94 Water transport accidents
0.618 0.382 0.000
V80-V89 Other land transport accidents
0.618 0.382 0.000
V70-V79 Bus occupant injured in transport accident
0.618 0.382 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.618 0.382 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.618 0.382 0.000
V40-V49 Car occupant injured in transport accident
0.618 0.382 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.618 0.382 0.000
V01-V09 Pedestrian injured in transport accident
0.618 0.382 0.000
H33.4 Traction detachment of retina
0.618 0.382 0.000
H33.1 Retinoschisis and retinal cysts
0.618 0.382 0.000
H33.5 Other retinal detachments
0.618 0.382 0.000
M20.5 Other deformities of toe(s) (acquired)
0.618 0.382 0.000
I60-I69 Cerebrovascular diseases
0.617 0.383 0.000
M22 Disorders of patella
0.617 0.383 0.000
Q82 Other congenital malformations of skin
0.616 0.384 0.000
R12 Heartburn
0.615 0.385 0.000
R25 Abnormal involuntary movements
0.614 0.386 0.000
K22.8 Other specified diseases of oesophagus
0.613 0.387 0.000
R26 Abnormalities of gait and mobility
0.613 0.387 0.000
Y40 Systemic antibiotics
0.611 0.389 0.000
M14 Arthropathies in other diseases classified elsewhere
0.610 0.389 0.000
M12 Other specific arthropathies
0.610 0.389 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.610 0.389 0.000
M08 Juvenile arthritis
0.610 0.389 0.000
M13.9 Arthritis, unspecified
0.608 0.392 0.000
V10-V19 Pedal cyclist injured in transport accident
0.608 0.392 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.608 0.392 0.000
K12.2 Cellulitis and abscess of mouth
0.608 0.392 0.000
K12.0 Recurrent oral aphthae
0.608 0.392 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.607 0.392 0.000
K09.9 Cyst of oral region, unspecified
0.607 0.393 0.000
K09.2 Other cysts of jaw
0.607 0.393 0.000
K09.1 Developmental (nonodontogenic) cysts of oral region
0.607 0.393 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.607 0.393 0.000
K76 Other diseases of liver
0.607 0.393 0.000
H73.9 Disorder of tympanic membrane, unspecified
0.606 0.393 0.000
H73.1 Chronic myringitis
0.606 0.393 0.000
H73.0 Acute myringitis
0.606 0.393 0.000
M31.6 Other giant cell arteritis
0.606 0.393 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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