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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9355814
log Bayes Factor = 5.58429
Chromosome 6   position 161,031,253  (GRCh37) Explore rs9355814 on Ensembl!
Variant rs9355814 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.001 0.999
I25.2 Old myocardial infarction
0.000 0.006 0.994
I20-I25 Ischaemic heart diseases
0.000 0.029 0.971
I20 Angina pectoris
0.000 0.030 0.970
I20.9 Angina pectoris, unspecified
0.000 0.032 0.968
I20.1 Angina pectoris with documented spasm
0.000 0.177 0.823
I22 Subsequent myocardial infarction
0.000 0.222 0.778
I20.0 Unstable angina
0.000 0.226 0.774
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.274 0.726
I23 Certain current complications following acute myocardial infarction
0.000 0.277 0.723
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I20.8 Other forms of angina pectoris
0.000 0.288 0.712
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.298 0.702
I25.3 Aneurysm of heart
0.000 0.322 0.678
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.363 0.637
I25.4 Coronary artery aneurysm
0.000 0.393 0.607
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.413 0.586
I23.8 Other current complications following acute myocardial infarction
0.000 0.455 0.545
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.482 0.518
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.482 0.518
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.482 0.518
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.482 0.518
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.482 0.518
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.482 0.518
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.482 0.518
I25.5 Ischaemic cardiomyopathy
0.000 0.489 0.510
I22.8 Subsequent myocardial infarction of other sites
0.000 0.582 0.418
I21 Acute myocardial infarction
0.000 0.644 0.356
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.698 0.302
I21.9 Acute myocardial infarction, unspecified
0.000 0.710 0.290
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.745 0.255
A49.8 Other bacterial infections of unspecified site
0.240 0.760 0.000
A49.0 Staphylococcal infection, unspecified
0.233 0.767 0.000
A49 Bacterial infection of unspecified site
0.229 0.771 0.000
I24 Other acute ischaemic heart diseases
0.000 0.774 0.226
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.786 0.214
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.790 0.210
I21.4 Acute subendocardial myocardial infarction
0.000 0.808 0.192
A49.1 Streptococcal infection, unspecified
0.188 0.812 0.000
A49.3 Mycoplasma infection, unspecified
0.164 0.836 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.843 0.157
I24.8 Other forms of acute ischaemic heart disease
0.000 0.855 0.145
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.863 0.137
A49.2 Haemophilus influenzae infection, unspecified
0.136 0.864 0.000
I24.1 Dressler's syndrome
0.000 0.891 0.109
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.911 0.089
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.913 0.087
A49.9 Bacterial infection, unspecified
0.086 0.914 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.916 0.084
Chapter IX Diseases of the circulatory system
0.000 0.922 0.078
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.923 0.077
I71 Aortic aneurysm and dissection
0.000 0.925 0.075
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.925 0.075
I10-I15 Hypertensive diseases
0.000 0.926 0.074
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.928 0.072
I77 Other disorders of arteries and arterioles
0.000 0.929 0.071
I11 Hypertensive heart disease
0.000 0.929 0.071
I10 Essential (primary) hypertension
0.000 0.929 0.071
I77.1 Stricture of artery
0.000 0.930 0.070
Z95.1 Presence of aortocoronary bypass graft
0.000 0.933 0.067
I70 Atherosclerosis
0.000 0.933 0.067
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.933 0.067
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.935 0.065
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.935 0.065
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.937 0.063
E78.2 Mixed hyperlipidaemia
0.000 0.938 0.062
A30-A49 Other bacterial diseases
0.061 0.939 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.940 0.060
Z82.2 Family history of deafness and hearing loss
0.000 0.941 0.059
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.941 0.059
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.943 0.057
E78.5 Hyperlipidaemia, unspecified
0.000 0.943 0.057
I71.0 Dissection of aorta [any part]
0.000 0.945 0.055
I70.1 Atherosclerosis of renal artery
0.000 0.945 0.055
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.945 0.055
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.946 0.054
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.946 0.054
I70.0 Atherosclerosis of aorta
0.000 0.947 0.053
I77.2 Rupture of artery
0.000 0.947 0.053
I15 Secondary hypertension
0.000 0.947 0.053
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.948 0.052
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.948 0.052
I78 Diseases of capillaries
0.000 0.948 0.052
I77.5 Necrosis of artery
0.000 0.949 0.051
I77.4 Coeliac artery compression syndrome
0.000 0.949 0.051
I77.3 Arterial fibromuscular dysplasia
0.000 0.949 0.051
I70.8 Atherosclerosis of other arteries
0.000 0.949 0.051
I00-I02 Acute rheumatic fever
0.000 0.950 0.050
I70.9 Generalised and unspecified atherosclerosis
0.000 0.950 0.050
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.950 0.050
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.951 0.049
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.951 0.049
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.951 0.049
Z82.1 Family history of blindness and visual loss
0.000 0.952 0.048
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.952 0.048
A40 Streptococcal septicaemia
0.048 0.952 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.952 0.047
A39 Meningococcal infection
0.047 0.953 0.000
I77.0 Arteriovenous fistula, acquired
0.000 0.953 0.047
I13 Hypertensive heart and renal disease
0.000 0.953 0.047
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.954 0.046
E78.1 Pure hyperglyceridaemia
0.000 0.954 0.046
A46 Erysipelas
0.046 0.954 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.955 0.045
E78.3 Hyperchylomicronaemia
0.000 0.955 0.045
A48 Other bacterial diseases, not elsewhere classified
0.045 0.955 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.955 0.045
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.955 0.045
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.956 0.044
A44 Bartonellosis
0.044 0.956 0.000
A43 Nocardiosis
0.044 0.956 0.000
A42 Actinomycosis
0.044 0.956 0.000
A37 Whooping cough
0.044 0.956 0.000
A36 Diphtheria
0.044 0.956 0.000
A32 Listeriosis
0.044 0.956 0.000
A30 Leprosy [Hansen's disease]
0.044 0.956 0.000
A38 Scarlet fever
0.044 0.956 0.000
A35 Other tetanus
0.044 0.956 0.000
A34 Obstetrical tetanus
0.044 0.956 0.000
A33 Tetanus neonatorum
0.044 0.956 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.956 0.044
I77.8 Other specified disorders of arteries and arterioles
0.000 0.956 0.044
I15.9 Seconday hypertension, unspecified
0.000 0.957 0.042
A40.9 Streptococcal septicaemia, unspecified
0.042 0.957 0.000
E78.4 Other hyperlipidaemia
0.000 0.959 0.040
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.960 0.040
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.960 0.040
E78.8 Other disorders of lipoprotein metabolism
0.000 0.960 0.040
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.960 0.039
A39.4 Meningococcaemia, unspecified
0.040 0.960 0.000
A40.8 Other streptococcal septicaemia
0.039 0.961 0.000
I05-I09 Chronic rheumatic heart diseases
0.000 0.961 0.039
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.962 0.038
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.001 0.962 0.038
I15.1 Hypertension secondary to other renal disorders
0.000 0.962 0.038
I15.2 Hypertension secondary to endocrine disorders
0.000 0.962 0.038
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.962 0.037
I73 Other peripheral vascular diseases
0.000 0.963 0.037
I78.9 Disease of capillaries, unspecified
0.000 0.963 0.037
E78.6 Lipoprotein deficiency
0.000 0.963 0.037
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.963 0.037
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.963 0.037
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.964 0.036
I02 Rheumatic chorea
0.000 0.964 0.036
I01 Rheumatic fever with heart involvement
0.000 0.964 0.036
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.964 0.036
I15.0 Renovascular hypertension
0.000 0.964 0.036
A48.1 Legionnaires' disease
0.036 0.964 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.965 0.035
A40.2 Septicaemia due to streptococcus, group D
0.034 0.966 0.000
A39.9 Meningococcal infection, unspecified
0.034 0.966 0.000
A39.8 Other meningococcal infections
0.034 0.966 0.000
A39.5 Meningococcal heart disease
0.034 0.966 0.000
A39.3 Chronic meningococcaemia
0.034 0.966 0.000
A39.2 Acute meningococcaemia
0.034 0.966 0.000
A39.1 Waterhouse-Friderichsen syndrome
0.034 0.966 0.000
A31 Infection due to other mycobacteria
0.034 0.966 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.966 0.034
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.966 0.034
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.966 0.034
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.000 0.967 0.033
Z95.0 Presence of cardiac pacemaker
0.000 0.967 0.033
A40.0 Septicaemia due to streptococcus, group A
0.033 0.967 0.000
A48.4 Brazilian purpuric fever
0.032 0.967 0.000
A48.3 Toxic shock syndrome
0.032 0.967 0.000
A48.2 Nonpneumonic Legionnaires' disease [Pontiac fever]
0.032 0.967 0.000
A48.0 Gas gangrene
0.032 0.967 0.000
I28 Other diseases of pulmonary vessels
0.000 0.967 0.032
I15.8 Other secondary hypertension
0.000 0.968 0.032
I78.8 Other diseases of capillaries
0.000 0.968 0.032
A30.9 Leprosy, unspecified
0.031 0.968 0.000
A30.8 Other forms of leprosy
0.031 0.968 0.000
A30.5 Lepromatous leprosy
0.031 0.968 0.000
A30.4 Borderline lepromatous leprosy
0.031 0.968 0.000
A30.3 Borderline leprosy
0.031 0.968 0.000
A30.2 Borderline tuberculoid leprosy
0.031 0.968 0.000
A30.1 Tuberculoid leprosy
0.031 0.968 0.000
A30.0 Indeterminate leprosy
0.031 0.968 0.000
A32.9 Listeriosis, unspecified
0.031 0.968 0.000
A32.8 Other forms of listeriosis
0.031 0.968 0.000
A32.7 Listerial septicaemia
0.031 0.968 0.000
A32.1 Listerial meningitis and meningoencephalitis
0.031 0.968 0.000
A32.0 Cutaneous listeriosis
0.031 0.968 0.000
A36.9 Diphtheria, unspecified
0.031 0.968 0.000
A36.8 Other diphtheria
0.031 0.968 0.000
A36.3 Cutaneous diphtheria
0.031 0.968 0.000
A36.2 Laryngeal diphtheria
0.031 0.968 0.000
A36.1 Nasopharyngeal diphtheria
0.031 0.968 0.000
A36.0 Pharyngeal diphtheria
0.031 0.968 0.000
A37.9 Whooping cough, unspecified
0.031 0.968 0.000
A37.8 Whooping cough due to other Bordetella species
0.031 0.968 0.000
A37.1 Whooping cough due to Bordetella parapertussis
0.031 0.968 0.000
A37.0 Whooping cough due to Bordetella pertussis
0.031 0.968 0.000
A42.9 Actinomycosis, unspecified
0.031 0.968 0.000
A42.8 Other forms of actinomycosis
0.031 0.968 0.000
A42.7 Actinomycotic septicaemia
0.031 0.968 0.000
A42.2 Cervicofacial actinomycosis
0.031 0.968 0.000
A42.1 Abdominal actinomycosis
0.031 0.968 0.000
A42.0 Pulmonary actinomycosis
0.031 0.968 0.000
A43.9 Nocardiosis, unspecified
0.031 0.968 0.000
A43.8 Other forms of nocardiosis
0.031 0.968 0.000
A43.1 Cutaneous nocardiosis
0.031 0.968 0.000
A43.0 Pulmonary nocardiosis
0.031 0.968 0.000
A44.9 Bartonellosis, unspecified
0.031 0.968 0.000
A44.8 Other forms of bartonellosis
0.031 0.968 0.000
A44.1 Cutaneous and mucocutaneous bartonellosis
0.031 0.968 0.000
A44.0 Systemic bartonellosis
0.031 0.968 0.000
I27 Other pulmonary heart diseases
0.000 0.969 0.031
I99 Other and unspecified disorders of circulatory system
0.000 0.969 0.031
I73.9 Peripheral vascular disease, unspecified
0.000 0.969 0.031
A39.0 Meningococcal meningitis
0.031 0.969 0.000
I00 Rheumatic fever without mention of heart involvement
0.000 0.969 0.030
A40.1 Septicaemia due to streptococcus, group B
0.030 0.969 0.000
I05 Rheumatic mitral valve diseases
0.000 0.970 0.030
I27.9 Pulmonary heart disease, unspecified
0.000 0.970 0.030
I07 Rheumatic tricuspid valve diseases
0.000 0.970 0.030
A48.8 Other specified bacterial diseases
0.029 0.970 0.000
Z95.3 Presence of xenogenic heart valve
0.000 0.971 0.029
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.972 0.028
I79.1 Aortitis in diseases classified elsewhere
0.001 0.972 0.027
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.001 0.972 0.027
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.973 0.027
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.973 0.027
I09 Other rheumatic heart diseases
0.000 0.973 0.027
I28.8 Other specified diseases of pulmonary vessels
0.000 0.973 0.027
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.974 0.026
I01.8 Other acute rheumatic heart disease
0.000 0.974 0.026
I01.2 Acute rheumatic myocarditis
0.000 0.974 0.026
I01.1 Acute rheumatic endocarditis
0.000 0.974 0.026
I01.0 Acute rheumatic pericarditis
0.000 0.974 0.026
I02.9 Rheumatic chorea without heart involvement
0.000 0.974 0.026
I02.0 Rheumatic chorea with heart involvement
0.000 0.974 0.026
I06 Rheumatic aortic valve diseases
0.000 0.974 0.026
I05.2 Mitral stenosis with insufficiency
0.000 0.975 0.025
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.975 0.025
I77.6 Arteritis, unspecified
0.000 0.975 0.025
I05.0 Mitral stenosis
0.000 0.975 0.025
A31.8 Other mycobacterial infections
0.024 0.975 0.000
A31.1 Cutaneous mycobacterial infection
0.024 0.975 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.976 0.024
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.976 0.023
I28.1 Aneurysm of pulmonary artery
0.000 0.976 0.023
I07.1 Tricuspid insufficiency
0.000 0.977 0.023
I72 Other aneurysm
0.001 0.977 0.022
I73.8 Other specified peripheral vascular diseases
0.000 0.977 0.023
I05.1 Rheumatic mitral insufficiency
0.000 0.977 0.023
A40.3 Septicaemia due to Streptococcus pneumoniae
0.023 0.977 0.000
I27.2 Other secondary pulmonary hypertension
0.000 0.977 0.023
I27.1 Kyphoscoliotic heart disease
0.000 0.977 0.023
I72.4 Aneurysm of artery of lower extremity
0.000 0.978 0.022
I07.9 Tricuspid valve disease, unspecified
0.000 0.978 0.021
I07.8 Other tricuspid valve diseases
0.000 0.978 0.021
I07.2 Tricuspid stenosis with insufficiency
0.000 0.978 0.021
I07.0 Tricuspid stenosis
0.000 0.978 0.021
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.979 0.021
I26 Pulmonary embolism
0.000 0.979 0.021
I74 Arterial embolism and thrombosis
0.000 0.979 0.021
I95 Hypotension
0.000 0.979 0.021
A31.9 Mycobacterial infection, unspecified
0.021 0.979 0.000
I12 Hypertensive renal disease
0.000 0.979 0.021
I05.8 Other mitral valve diseases
0.000 0.980 0.020
I06.1 Rheumatic aortic insufficiency
0.000 0.980 0.020
I95.0 Idiopathic hypotension
0.000 0.980 0.020
I97.1 Other functional disturbances following cardiac surgery
0.000 0.980 0.020
A31.0 Pulmonary mycobacterial infection
0.020 0.980 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.980 0.019
I09.8 Other specified rheumatic heart diseases
0.000 0.981 0.019
I09.2 Chronic rheumatic pericarditis
0.000 0.981 0.019
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.981 0.019
I09.0 Rheumatic myocarditis
0.000 0.981 0.019
I97.0 Postcardiotomy syndrome
0.000 0.981 0.019
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.981 0.018
I06.8 Other rheumatic aortic valve diseases
0.000 0.981 0.018
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.981 0.018
I09.9 Rheumatic heart disease, unspecified
0.000 0.982 0.018
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.982 0.018
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.983 0.017
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.983 0.017
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.983 0.017
I98.0 Cardiovascular syphilis
0.000 0.983 0.017
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.983 0.017
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.983 0.017
I72.6 Aneurysm and dissection of vertebral artery
0.001 0.983 0.016
I72.5 Aneurysm and dissection of other precerebral arteries
0.001 0.983 0.016
I27.8 Other specified pulmonary heart diseases
0.000 0.984 0.016
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.984 0.016
I45.6 Preexcitation syndrome
0.000 0.985 0.015
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.985 0.015
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.985 0.015
I46.0 Cardiac arrest with successful resuscitation
0.000 0.985 0.015
I72.2 Aneurysm of renal artery
0.001 0.985 0.014
A41 Other septicaemia
0.015 0.985 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.985 0.014
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.986 0.014
I31.9 Disease of pericardium, unspecified
0.000 0.986 0.014
I45 Other conduction disorders
0.000 0.986 0.014
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.986 0.014
M79.79 Fibromyalgia (Site unspecified)
0.000 0.986 0.014
I06.0 Rheumatic aortic stenosis
0.000 0.986 0.014
H18.5 Hereditary corneal dystrophies
0.014 0.986 0.000
I72.9 Aneurysm of unspecified site
0.001 0.986 0.013
I46 Cardiac arrest
0.000 0.986 0.014
I72.1 Aneurysm of artery of upper extremity
0.001 0.986 0.013
I74.8 Embolism and thrombosis of other arteries
0.000 0.986 0.013
I30-I52 Other forms of heart disease
0.000 0.987 0.013
I05.9 Mitral valve disease, unspecified
0.000 0.987 0.013
I31 Other diseases of pericardium
0.000 0.987 0.013
I95.9 Hypotension, unspecified
0.000 0.987 0.013
H18 Other disorders of cornea
0.013 0.987 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.013 0.987 0.000
I95.8 Other hypotension
0.000 0.987 0.012
Z95.4 Presence of other heart-valve replacement
0.000 0.987 0.012
I72.0 Aneurysm of carotid artery
0.001 0.988 0.012
I45.9 Conduction disorder, unspecified
0.000 0.988 0.012
A41.0 Septicaemia due to Staphylococcus aureus
0.012 0.988 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.988 0.012
I30 Acute pericarditis
0.000 0.988 0.012
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.001 0.988 0.011
Z82.3 Family history of stroke
0.000 0.988 0.012
I45.1 Other and unspecified right bundle-branch block
0.000 0.988 0.012
I45.5 Other specified heart block
0.000 0.988 0.012
I95.2 Hypotension due to drugs
0.000 0.989 0.011
I31.1 Chronic constrictive pericarditis
0.000 0.989 0.011
I35 Nonrheumatic aortic valve disorders
0.000 0.989 0.011
E27.1 Primary adrenocortical insufficiency
0.000 0.989 0.011
I73.0 Raynaud's syndrome
0.000 0.989 0.011
A41.4 Septicaemia due to anaerobes
0.011 0.989 0.000
H18.4 Corneal degeneration
0.011 0.989 0.000
E27 Other disorders of adrenal gland
0.000 0.989 0.011
I72.3 Aneurysm of iliac artery
0.001 0.989 0.010
I30.9 Acute pericarditis, unspecified
0.000 0.989 0.011
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.989 0.011
H18.9 Disorder of cornea, unspecified
0.011 0.989 0.000
H18.0 Corneal pigmentations and deposits
0.011 0.989 0.000
I74.5 Embolism and thrombosis of iliac artery
0.000 0.989 0.011
I35.1 Aortic (valve) insufficiency
0.000 0.989 0.011
I45.4 Nonspecific intraventricular block
0.000 0.989 0.011
H18.3 Changes in corneal membranes
0.011 0.989 0.000
H18.2 Other corneal oedema
0.011 0.989 0.000
E27.2 Addisonian crisis
0.000 0.989 0.010
I45.0 Right fascicular block
0.000 0.989 0.010
I40 Acute myocarditis
0.000 0.990 0.010
S02.10 Fracture of base of skull (closed)
0.000 0.990 0.010
Z29.1 Prophylactic immunotherapy
0.000 0.990 0.010
I78.1 Naevus, nonneoplastic
0.000 0.990 0.010
I46.1 Sudden cardiac death, so described
0.000 0.990 0.010
A41.5 Septicaemia due to other Gram-negative organisms
0.010 0.990 0.000
I30.1 Infective pericarditis
0.000 0.990 0.010
I35.0 Aortic (valve) stenosis
0.000 0.990 0.010
I52 Other heart disorders in diseases classified elsewhere
0.000 0.990 0.010
I48 Atrial fibrillation and flutter
0.000 0.990 0.010
I41 Myocarditis in diseases classified elsewhere
0.000 0.990 0.010
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.990 0.010
I32 Pericarditis in diseases classified elsewhere
0.000 0.990 0.010
I31.8 Other specified diseases of pericardium
0.000 0.990 0.010
I31.2 Haemopericardium, not elsewhere classified
0.000 0.990 0.010
I45.2 Bifascicular block
0.000 0.990 0.010
H18.6 Keratoconus
0.010 0.990 0.000
H18.1 Bullous keratopathy
0.010 0.990 0.000
I35.9 Aortic valve disorder, unspecified
0.000 0.991 0.009
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.991 0.009
H18.7 Other corneal deformities
0.009 0.991 0.000
I36 Nonrheumatic tricuspid valve disorders
0.000 0.991 0.009
M25.76 Osteophyte (Lower leg)
0.000 0.991 0.009
I37 Pulmonary valve disorders
0.000 0.991 0.009
E27.9 Disorder of adrenal gland, unspecified
0.000 0.991 0.009
Z29.8 Other specified prophylactic measures
0.000 0.991 0.009
A41.2 Septicaemia due to unspecified staphylococcus
0.009 0.991 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.991 0.009
T43.0 Tricyclic and tetracyclic antidepressants
0.009 0.991 0.000
H18.8 Other specified disorders of cornea
0.009 0.991 0.000
Z29 Need for other prophylactic measures
0.000 0.991 0.009
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.991 0.009
M25.72 Osteophyte (Upper arm)
0.000 0.991 0.009
I46.9 Cardiac arrest, unspecified
0.000 0.992 0.008
M77.91 Enthesopathy, unspecified (Shoulder region)
0.000 0.992 0.008
Z29.2 Other prophylactic chemotherapy
0.000 0.992 0.008
A63.0 Anogenital (venereal) warts
0.008 0.992 0.000
I40.9 Acute myocarditis, unspecified
0.000 0.992 0.008
M79.7 Fibromyalgia
0.000 0.992 0.008
E27.5 Adrenomedullary hyperfunction
0.000 0.992 0.008
E27.0 Other adrenocortical overactivity
0.000 0.992 0.008
I45.3 Trifascicular block
0.000 0.992 0.008
I27.0 Primary pulmonary hypertension
0.000 0.992 0.008
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.008 0.992 0.000
M25.7 Osteophyte
0.000 0.992 0.008
U80.1 Methicillin resistant agent
0.008 0.992 0.000
I31.0 Chronic adhesive pericarditis
0.000 0.992 0.007
I40.8 Other acute myocarditis
0.000 0.992 0.007
I40.1 Isolated myocarditis
0.000 0.992 0.007
A41.1 Septicaemia due to other specified staphylococcus
0.008 0.992 0.000
I12.9 Hypertensive renal disease without renal failure
0.000 0.992 0.007
I40.0 Infective myocarditis
0.000 0.993 0.007
M25.77 Osteophyte (Ankle and foot)
0.000 0.993 0.007
A50-A64 Infections with a predominantly sexual mode of transmission
0.007 0.993 0.000
R40.2 Coma, unspecified
0.000 0.993 0.007
I30.8 Other forms of acute pericarditis
0.000 0.993 0.007
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.993 0.007
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.993 0.007
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.993 0.007
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.993 0.007
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.993 0.007
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.993 0.007
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.993 0.007
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.993 0.007
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.993 0.007
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.993 0.007
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.993 0.007
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.993 0.007
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.993 0.007
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.993 0.007
I48.4 Atypical atrial flutter
0.000 0.993 0.007
I48.3 Typical atrial flutter
0.000 0.993 0.007
I48.2 Chronic atrial fibrillation
0.000 0.993 0.007
I48.1 Persistent atrial fibrillation
0.000 0.993 0.007
I48.0 Paroxysmal atrial fibrillation
0.000 0.993 0.007
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.993 0.007
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.993 0.007
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.993 0.007
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.007 0.993 0.000
M79.70 Fibromyalgia (Multiple sites)
0.000 0.993 0.007
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.993 0.007
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.993 0.007
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.993 0.007
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.993 0.007
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.993 0.007
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.993 0.007
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.993 0.007
I72.8 Aneurysm of other specified arteries
0.002 0.993 0.006
I45.8 Other specified conduction disorders
0.000 0.993 0.007
I31.3 Pericardial effusion (noninflammatory)
0.000 0.993 0.007
I37.9 Pulmonary valve disorder, unspecified
0.000 0.993 0.007
I37.8 Other pulmonary valve disorders
0.000 0.993 0.007
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.993 0.007
I37.0 Pulmonary valve stenosis
0.000 0.993 0.007
E27.8 Other specified disorders of adrenal gland
0.000 0.993 0.007
I35.8 Other aortic valve disorders
0.000 0.993 0.007
I08 Multiple valve diseases
0.000 0.993 0.007
M25.79 Osteophyte (Site unspecified)
0.000 0.993 0.007
A63.8 Other specified predominantly sexually transmitted diseases
0.007 0.993 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.993 0.007
A60 Anogenital herpesviral [herpes simplex] infections
0.007 0.993 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.993 0.006
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.993 0.006
Z29.9 Prophylactic measure, unspecified
0.000 0.994 0.006
M25.86 Other specified joint disorders (Lower leg)
0.000 0.994 0.006
Chapter I Certain infectious and parasitic diseases
0.006 0.994 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.006 0.994 0.000
T14.0 Superficial injury of unspecified body region
0.006 0.994 0.000
I33 Acute and subacute endocarditis
0.000 0.994 0.006
I37.1 Pulmonary valve insufficiency
0.000 0.994 0.006
M79.78 Fibromyalgia (Other)
0.000 0.994 0.006
M79.77 Fibromyalgia (Ankle and foot)
0.000 0.994 0.006
M79.76 Fibromyalgia (Lower leg)
0.000 0.994 0.006
M79.75 Fibromyalgia (Pelvic region and thigh)
0.000 0.994 0.006
M79.74 Fibromyalgia (Hand)
0.000 0.994 0.006
M79.73 Fibromyalgia (Forearm)
0.000 0.994 0.006
M79.72 Fibromyalgia (Upper arm)
0.000 0.994 0.006
M79.71 Fibromyalgia (Shoulder region)
0.000 0.994 0.006
A60.0 Herpesviral infection of genitalia and urogenital tract
0.006 0.994 0.000
M25.73 Osteophyte (Forearm)
0.000 0.994 0.006
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.994 0.006
M25.78 Osteophyte (Other)
0.000 0.994 0.006
M25.70 Osteophyte (Multiple sites)
0.000 0.994 0.006
M25.74 Osteophyte (Hand)
0.000 0.994 0.006
T43.3 Phenothiazine antipsychotics and neuroleptics
0.006 0.994 0.000
A15-A19 Tuberculosis
0.006 0.994 0.000
T14 Injury of unspecified body region
0.006 0.994 0.000
A52 Late syphilis
0.006 0.994 0.000
A59 Trichomoniasis
0.005 0.994 0.000
A56 Other sexually transmitted chlamydial diseases
0.005 0.994 0.000
A54 Gonococcal infection
0.005 0.994 0.000
A53 Other and unspecified syphilis
0.005 0.994 0.000
A51 Early syphilis
0.005 0.994 0.000
A50 Congenital syphilis
0.005 0.994 0.000
A64 Unspecified sexually transmitted disease
0.005 0.994 0.000
A58 Granuloma inguinale
0.005 0.994 0.000
A57 Chancroid
0.005 0.994 0.000
A55 Chlamydial lymphogranuloma (venereum)
0.005 0.994 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.005 0.994 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.005 0.994 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.005 0.995 0.000
U80 Agent resistant to penicillin and related antibiotics
0.005 0.995 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.005 0.995 0.000
M77.9 Enthesopathy, unspecified
0.000 0.995 0.005
B20-B24 Human immunodeficiency virus [HIV] disease
0.005 0.995 0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation
0.005 0.995 0.000
A20-A28 Certain zoonotic bacterial diseases
0.005 0.995 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.000 0.995 0.005
A60.9 Anogenital herpesviral infection, unspecified
0.005 0.995 0.000
A60.1 Herpesviral infection of perianal skin and rectum
0.005 0.995 0.000
S02.1 Fracture of base of skull
0.000 0.995 0.005
T14.1 Open wound of unspecified body region
0.005 0.995 0.000
I51.6 Cardiovascular disease, unspecified
0.000 0.995 0.005
A65-A69 Other spirochaetal diseases
0.005 0.995 0.000
B65-B83 Helminthiases
0.005 0.995 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.005 0.995 0.000
S50.9 Superficial injury of forearm, unspecified
0.000 0.995 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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