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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9378164
log Bayes Factor = 72.2281
Chromosome 6   position 31,643,522  (GRCh37) Explore rs9378164 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.000 1.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
1.000 0.000 0.000
J33 Nasal polyp
0.000 0.000 1.000
F41 Other anxiety disorders
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.001 0.999
F30-F39 Mood [affective] disorders
0.999 0.001 0.000
J47 Bronchiectasis
0.000 0.001 0.999
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.995 0.005 0.000
J33.9 Nasal polyp, unspecified
0.000 0.005 0.995
E03.9 Hypothyroidism, unspecified
0.000 0.005 0.995
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.993 0.007 0.000
M07.3 Other psoriatic arthropathies
0.993 0.007 0.000
L40-L45 Papulosquamous disorders
0.993 0.007 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.992 0.008 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.990 0.010 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.990 0.010 0.000
F41.9 Anxiety disorder, unspecified
0.988 0.012 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.986 0.014 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.986 0.014 0.000
J33.0 Polyp of nasal cavity
0.000 0.015 0.985
L40.0 Psoriasis vulgaris
0.983 0.017 0.000
T43.2 Other and unspecified antidepressants
0.983 0.017 0.000
J34 Other disorders of nose and nasal sinuses
0.000 0.017 0.983
T39.1 4-Aminophenol derivatives
0.978 0.022 0.000
F31 Bipolar affective disorder
0.977 0.023 0.000
F33 Recurrent depressive disorder
0.972 0.028 0.000
J34.2 Deviated nasal septum
0.000 0.029 0.971
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.971 0.029 0.000
J30 Vasomotor and allergic rhinitis
0.000 0.032 0.968
F41.2 Mixed anxiety and depressive disorder
0.964 0.036 0.000
F60-F69 Disorders of adult personality and behaviour
0.961 0.039 0.000
G40-G47 Episodic and paroxysmal disorders
0.961 0.039 0.000
G40 Epilepsy
0.958 0.042 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.958 0.042 0.000
E03 Other hypothyroidism
0.000 0.042 0.957
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.950 0.050 0.000
G20-G26 Extrapyramidal and movement disorders
0.944 0.056 0.000
E00-E07 Disorders of thyroid gland
0.001 0.067 0.932
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.933 0.067 0.000
J30.1 Allergic rhinitis due to pollen
0.000 0.068 0.932
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.930 0.070 0.000
Chapter XIV Diseases of the genitourinary system
0.926 0.074 0.000
N20 Calculus of kidney and ureter
0.923 0.077 0.000
N20-N23 Urolithiasis
0.922 0.078 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.920 0.080 0.000
T51 Toxic effect of alcohol
0.917 0.083 0.000
F60 Specific personality disorders
0.916 0.084 0.000
M07 Psoriatic and enteropathic arthropathies
0.913 0.087 0.000
N20.1 Calculus of ureter
0.912 0.088 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.091 0.909
N20.0 Calculus of kidney
0.907 0.093 0.000
Q60-Q64 Congenital malformations of the urinary system
0.896 0.104 0.000
N10-N16 Renal tubulo-interstitial diseases
0.892 0.108 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.892 0.108 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.109 0.890
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.888 0.112 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.888 0.112 0.000
G70-G73 Diseases of myoneural junction and muscle
0.887 0.113 0.000
T51.0 Ethanol
0.886 0.114 0.000
G24 Dystonia
0.886 0.114 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.884 0.116 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.879 0.121 0.000
J34.3 Hypertrophy of nasal turbinates
0.000 0.124 0.876
Q50-Q56 Congenital malformations of genital organs
0.868 0.132 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.868 0.132 0.000
L40.8 Other psoriasis
0.866 0.134 0.000
F30 Manic episode
0.861 0.139 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.011 0.139 0.850
N60-N64 Disorders of breast
0.860 0.140 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.144 0.856
M05-M14 Inflammatory polyarthropathies
0.856 0.144 0.000
F33.9 Recurrent depressive disorder, unspecified
0.856 0.144 0.000
E10.9 Without complications
0.000 0.147 0.853
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.851 0.149 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.851 0.149 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.850 0.150 0.000
E10-E14 Diabetes mellitus
0.003 0.150 0.846
F31.9 Bipolar affective disorder, unspecified
0.849 0.151 0.000
N13 Obstructive and reflux uropathy
0.848 0.152 0.000
F41.1 Generalised anxiety disorder
0.847 0.153 0.000
J31.0 Chronic rhinitis
0.000 0.156 0.844
F31.8 Other bipolar affective disorders
0.843 0.157 0.000
F42 Obsessive-compulsive disorder
0.842 0.158 0.000
F40 Phobic anxiety disorders
0.841 0.159 0.000
F44 Dissociative [conversion] disorders
0.836 0.164 0.000
K70-K77 Diseases of liver
0.836 0.164 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.836 0.164 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.167 0.833
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.167 0.833
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.831 0.169 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.830 0.170 0.000
Chapter XI Diseases of the digestive system
0.829 0.171 0.000
J00-J06 Acute upper respiratory infections
0.000 0.173 0.827
F60.3 Emotionally unstable personality disorder
0.826 0.174 0.000
K76 Other diseases of liver
0.826 0.174 0.000
T39.0 Salicylates
0.826 0.174 0.000
G70 Myasthenia gravis and other myoneural disorders
0.825 0.175 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.824 0.176 0.000
F32 Depressive episode
0.824 0.176 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.177 0.823
T43.3 Phenothiazine antipsychotics and neuroleptics
0.822 0.178 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.000 0.178 0.822
F31.0 Bipolar affective disorder, current episode hypomanic
0.822 0.178 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.822 0.178 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.819 0.181 0.000
F34 Persistent mood [affective] disorders
0.817 0.183 0.000
T20 Burn and corrosion of head and neck
0.816 0.184 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.816 0.184 0.000
K76.8 Other specified diseases of liver
0.816 0.184 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.815 0.185 0.000
L40.1 Generalised pustular psoriasis
0.814 0.186 0.000
T79-T79 Certain early complications of trauma
0.813 0.187 0.000
G24.9 Dystonia, unspecified
0.811 0.189 0.000
J30.3 Other allergic rhinitis
0.000 0.191 0.809
T50.9 Other and unspecified drugs, medicaments and biological substances
0.808 0.192 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.808 0.192 0.000
J32 Chronic sinusitis
0.000 0.192 0.808
N10 Acute tubulo-interstitial nephritis
0.808 0.192 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.805 0.195 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.803 0.197 0.000
T21 Burn and corrosion of trunk
0.802 0.198 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.802 0.198 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.802 0.198 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.802 0.198 0.000
N61 Inflammatory disorders of breast
0.800 0.200 0.000
Q80-Q89 Other congenital malformations
0.800 0.200 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.799 0.201 0.000
K80 Cholelithiasis
0.798 0.202 0.000
F69 Unspecified disorder of adult personality and behaviour
0.795 0.204 0.000
J42 Unspecified chronic bronchitis
0.000 0.205 0.795
J03 Acute tonsillitis
0.000 0.209 0.790
G20 Parkinson's disease
0.789 0.211 0.000
F60.9 Personality disorder, unspecified
0.789 0.211 0.000
T42.1 Iminostilbenes
0.788 0.212 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.786 0.214 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.784 0.216 0.000
K90 Intestinal malabsorption
0.039 0.217 0.745
J37 Chronic laryngitis and laryngotracheitis
0.000 0.217 0.782
K74 Fibrosis and cirrhosis of liver
0.782 0.218 0.000
Q61 Cystic kidney disease
0.782 0.218 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.781 0.219 0.000
G70.0 Myasthenia gravis
0.780 0.220 0.000
N13.8 Other obstructive and reflux uropathy
0.780 0.220 0.000
J60-J70 Lung diseases due to external agents
0.000 0.220 0.780
J33.8 Other polyp of sinus
0.000 0.224 0.776
J46 Status asthmaticus
0.000 0.225 0.775
L42 Pityriasis rosea
0.774 0.226 0.000
G40.5 Special epileptic syndromes
0.774 0.226 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.773 0.227 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.773 0.227 0.000
T43.6 Psychostimulants with abuse potential
0.773 0.227 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.773 0.227 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.772 0.228 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.770 0.229 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.770 0.230 0.000
E10.3 With ophthalmic complications
0.000 0.231 0.769
N63 Unspecified lump in breast
0.768 0.232 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.768 0.232 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.767 0.233 0.000
J03.9 Acute tonsillitis, unspecified
0.000 0.235 0.765
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.764 0.236 0.000
K80.4 Calculus of bile duct with cholecystitis
0.758 0.242 0.000
Q21 Congenital malformations of cardiac septa
0.757 0.243 0.000
T90 Sequelae of injuries of head
0.756 0.244 0.000
M91-M94 Chondropathies
0.756 0.244 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.753 0.247 0.000
G45.3 Amaurosis fugax
0.753 0.247 0.000
S10-S19 Injuries to the neck
0.748 0.252 0.000
F45 Somatoform disorders
0.748 0.252 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.746 0.254 0.000
E10.1 With ketoacidosis
0.000 0.254 0.746
T23 Burn and corrosion of wrist and hand
0.745 0.255 0.000
G24.3 Spasmodic torticollis
0.742 0.258 0.000
F32.1 Moderate depressive episode
0.741 0.259 0.000
J86 Pyothorax
0.000 0.262 0.738
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.737 0.263 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.736 0.263 0.000
S70-S79 Injuries to the hip and thigh
0.736 0.264 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.735 0.264 0.000
K74.6 Other and unspecified cirrhosis of liver
0.732 0.268 0.000
F30.0 Hypomania
0.732 0.268 0.000
K72 Hepatic failure, not elsewhere classified
0.732 0.268 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.731 0.269 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.730 0.270 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.730 0.270 0.000
J36 Peritonsillar abscess
0.000 0.271 0.729
F40.2 Specific (isolated) phobias
0.728 0.272 0.000
J32.0 Chronic maxillary sinusitis
0.000 0.274 0.726
G00-G09 Inflammatory diseases of the central nervous system
0.724 0.276 0.000
F60.7 Dependent personality disorder
0.724 0.276 0.000
T91 Sequelae of injuries of neck and trunk
0.722 0.278 0.000
Chapter XX External causes of morbidity and mortality
0.722 0.278 0.000
Q00-Q07 Congenital malformations of the nervous system
0.721 0.279 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.721 0.279 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.720 0.280 0.000
K70 Alcoholic liver disease
0.718 0.282 0.000
T51.9 Alcohol, unspecified
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
F48 Other neurotic disorders
0.717 0.283 0.000
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
F41.8 Other specified anxiety disorders
0.717 0.283 0.000
F41.3 Other mixed anxiety disorders
0.717 0.283 0.000
J45.8 Mixed asthma
0.000 0.283 0.717
J45.1 Nonallergic asthma
0.000 0.283 0.717
F38 Other mood [affective] disorders
0.716 0.283 0.000
F39 Unspecified mood [affective] disorder
0.716 0.283 0.000
Q63 Other congenital malformations of kidney
0.716 0.284 0.000
N13.6 Pyonephrosis
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
N20.9 Urinary calculus, unspecified
0.715 0.285 0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand
0.715 0.285 0.000
K76.6 Portal hypertension
0.714 0.286 0.000
T43.9 Psychotropic drug, unspecified
0.713 0.287 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.713 0.287 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.713 0.287 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.712 0.288 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.712 0.288 0.000
T39.4 Antirheumatics, not elsewhere classified
0.712 0.288 0.000
T39.2 Pyrazolone derivatives
0.712 0.288 0.000
S32 Fracture of lumbar spine and pelvis
0.712 0.288 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.712 0.288 0.000
M07.38 Other psoriatic arthropathies (Other)
0.712 0.288 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.712 0.288 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.712 0.288 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.712 0.288 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.712 0.288 0.000
L44 Other papulosquamous disorders
0.712 0.288 0.000
L41 Parapsoriasis
0.712 0.288 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.712 0.288 0.000
T93 Sequelae of injuries of lower limb
0.712 0.288 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.710 0.290 0.000
Q35-Q37 Cleft lip and cleft palate
0.710 0.290 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.710 0.290 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.710 0.290 0.000
L10-L14 Bullous disorders
0.708 0.292 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.707 0.293 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.707 0.293 0.000
T42.3 Barbiturates
0.707 0.293 0.000
T42.2 Succinimides and oxazolidinediones
0.707 0.293 0.000
T42.0 Hydantoin derivatives
0.707 0.293 0.000
G25 Other extrapyramidal and movement disorders
0.704 0.296 0.000
Q51 Congenital malformations of uterus and cervix
0.703 0.297 0.000
K90.9 Intestinal malabsorption, unspecified
0.013 0.298 0.689
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.007 0.298 0.695
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.701 0.298 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.701 0.299 0.000
G24.8 Other dystonia
0.701 0.299 0.000
F31.7 Bipolar affective disorder, currently in remission
0.700 0.299 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.700 0.299 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.700 0.299 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.698 0.302 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.698 0.302 0.000
F33.8 Other recurrent depressive disorders
0.697 0.303 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.697 0.303 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.697 0.303 0.000
S90-S99 Injuries to the ankle and foot
0.697 0.303 0.000
E07 Other disorders of thyroid
0.001 0.304 0.695
K83 Other diseases of biliary tract
0.694 0.306 0.000
J30.2 Other seasonal allergic rhinitis
0.000 0.306 0.694
J30.0 Vasomotor rhinitis
0.000 0.306 0.694
K73 Chronic hepatitis, not elsewhere classified
0.692 0.308 0.000
N21 Calculus of lower urinary tract
0.691 0.309 0.000
F17.2 Dependence syndrome
0.691 0.309 0.000
F68 Other disorders of adult personality and behaviour
0.689 0.311 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.689 0.311 0.000
F65 Disorders of sexual preference
0.689 0.311 0.000
F64 Gender identity disorders
0.689 0.311 0.000
F63 Habit and impulse disorders
0.689 0.311 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.689 0.311 0.000
F61 Mixed and other personality disorders
0.689 0.311 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.689 0.311 0.000
T45.0 Antiallergic and antiemetic drugs
0.689 0.311 0.000
T98 Sequelae of other and unspecified effects of external causes
0.687 0.313 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.687 0.313 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.687 0.313 0.000
T25 Burn and corrosion of ankle and foot
0.687 0.313 0.000
E03.5 Myxoedema coma
0.000 0.313 0.686
E03.4 Atrophy of thyroid (acquired)
0.000 0.313 0.686
E03.3 Postinfectious hypothyroidism
0.000 0.313 0.686
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.313 0.686
E03.1 Congenital hypothyroidism without goitre
0.000 0.313 0.686
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.313 0.686
F34.1 Dysthymia
0.686 0.314 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.685 0.315 0.000
E10.4 With neurological complications
0.000 0.315 0.685
F99-F99 Unspecified mental disorder
0.684 0.315 0.000
Q21.1 Atrial septal defect
0.683 0.317 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.683 0.317 0.000
F44.5 Dissociative convulsions
0.682 0.318 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.682 0.318 0.000
T65 Toxic effect of other and unspecified substances
0.681 0.319 0.000
T62 Toxic effect of other noxious substances eaten as food
0.681 0.319 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.681 0.319 0.000
T60 Toxic effect of pesticides
0.681 0.319 0.000
T59 Toxic effect of other gases, fumes and vapours
0.681 0.319 0.000
T57 Toxic effect of other inorganic substances
0.681 0.319 0.000
T56 Toxic effect of metals
0.681 0.319 0.000
T54 Toxic effect of corrosive substances
0.681 0.319 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.681 0.319 0.000
T52 Toxic effect of organic solvents
0.681 0.319 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.681 0.319 0.000
T58 Toxic effect of carbon monoxide
0.681 0.319 0.000
T55 Toxic effect of soaps and detergents
0.681 0.319 0.000
F42.9 Obsessive-compulsive disorder, unspecified
0.681 0.319 0.000
M94 Other disorders of cartilage
0.681 0.319 0.000
K74.0 Hepatic fibrosis
0.680 0.320 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.679 0.321 0.000
K72.9 Hepatic failure, unspecified
0.679 0.321 0.000
T20.1 Burn of first degree of head and neck
0.678 0.322 0.000
K76.7 Hepatorenal syndrome
0.677 0.323 0.000
G23 Other degenerative diseases of basal ganglia
0.677 0.323 0.000
G21 Secondary Parkinsonism
0.677 0.323 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.677 0.323 0.000
G22 Parkinsonism in diseases classified elsewhere
0.677 0.323 0.000
J44 Other chronic obstructive pulmonary disease
0.000 0.324 0.676
F30.9 Manic episode, unspecified
0.675 0.325 0.000
Q54 Hypospadias
0.675 0.325 0.000
F42.0 Predominantly obsessional thoughts or ruminations
0.674 0.326 0.000
E10.2 With renal complications
0.000 0.326 0.674
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.673 0.327 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.673 0.327 0.000
Q61.0 Congenital single renal cyst
0.672 0.328 0.000
F43 Reaction to severe stress, and adjustment disorders
0.672 0.328 0.000
J86.9 Pyothorax without fistula
0.000 0.330 0.670
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.001 0.331 0.668
E00 Congenital iodine-deficiency syndrome
0.001 0.331 0.668
E02 Subclinical iodine-deficiency hypothyroidism
0.001 0.331 0.668
E06 Thyroiditis
0.001 0.331 0.668
E03.8 Other specified hypothyroidism
0.000 0.332 0.668
S79 Other and unspecified injuries of hip and thigh
0.667 0.333 0.000
J30.4 Allergic rhinitis, unspecified
0.000 0.337 0.663
N22 Calculus of urinary tract in diseases classified elsewhere
0.661 0.339 0.000
T63 Toxic effect of contact with venomous animals
0.659 0.341 0.000
T51.8 Other alcohols
0.657 0.343 0.000
T51.3 Fusel oil
0.657 0.343 0.000
T51.2 2-Propanol
0.657 0.343 0.000
T51.1 Methanol
0.657 0.343 0.000
M11 Other crystal arthropathies
0.657 0.343 0.000
J40 Bronchitis, not specified as acute or chronic
0.000 0.343 0.657
F60.8 Other specific personality disorders
0.657 0.343 0.000
F60.6 Anxious [avoidant] personality disorder
0.657 0.343 0.000
F60.5 Anankastic personality disorder
0.657 0.343 0.000
F60.4 Histrionic personality disorder
0.657 0.343 0.000
F60.2 Dissocial personality disorder
0.657 0.343 0.000
F60.1 Schizoid personality disorder
0.657 0.343 0.000
F60.0 Paranoid personality disorder
0.657 0.343 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.656 0.344 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.344 0.656
F44.9 Dissociative [conversion] disorder, unspecified
0.655 0.344 0.000
T31 Burns classified according to extent of body surface involved
0.655 0.345 0.000
M07.6 Other enteropathic arthropathies
0.655 0.345 0.000
M07.5 Arthropathy in ulcerative colitis
0.655 0.345 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.655 0.345 0.000
M07.2 Psoriatic spondylitis
0.655 0.345 0.000
M07.1 Arthritis mutilans
0.655 0.345 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.655 0.345 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.653 0.347 0.000
M40-M43 Deforming dorsopathies
0.653 0.347 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.347 0.653
W20-W49 Exposure to inanimate mechanical forces
0.652 0.348 0.000
F29 Unspecified nonorganic psychosis
0.652 0.348 0.000
J31.2 Chronic pharyngitis
0.000 0.348 0.652
J31.1 Chronic nasopharyngitis
0.000 0.348 0.652
M14 Arthropathies in other diseases classified elsewhere
0.651 0.349 0.000
T90.8 Sequelae of other specified injuries of head
0.650 0.350 0.000
Q76 Congenital malformations of spine and bony thorax
0.649 0.351 0.000
M00-M03 Infectious arthropathies
0.649 0.351 0.000
T20.2 Burn of second degree of head and neck
0.647 0.353 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.646 0.354 0.000
S31 Open wound of abdomen, lower back and pelvis
0.646 0.354 0.000
T21.0 Burn of unspecified degree of trunk
0.645 0.354 0.000
F32.0 Mild depressive episode
0.644 0.356 0.000
Q64 Other congenital malformations of urinary system
0.642 0.357 0.000
N13.4 Hydroureter
0.642 0.358 0.000
T21.3 Burn of third degree of trunk
0.641 0.359 0.000
K82 Other diseases of gallbladder
0.641 0.359 0.000
J01 Acute sinusitis
0.000 0.359 0.641
Q63.1 Lobulated, fused and horseshoe kidney
0.640 0.360 0.000
G71 Primary disorders of muscles
0.640 0.360 0.000
J90-J94 Other diseases of pleura
0.000 0.360 0.640
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.640 0.360 0.000
N15 Other renal tubulo-interstitial diseases
0.640 0.360 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.640 0.360 0.000
T38.9 Other and unspecified hormone antagonists
0.640 0.360 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.640 0.360 0.000
T38.7 Androgens and anabolic congeners
0.640 0.360 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.640 0.360 0.000
T38.5 Other oestrogens and progestogens
0.640 0.360 0.000
T38.4 Oral contraceptives
0.640 0.360 0.000
T38.2 Antithyroid drugs
0.640 0.360 0.000
T38.1 Thyroid hormones and substitutes
0.640 0.360 0.000
T38.0 Glucocorticoids and synthetic analogues
0.640 0.360 0.000
E05.8 Other thyrotoxicosis
0.000 0.361 0.638
E05.5 Thyroid crisis or storm
0.000 0.361 0.638
E05.4 Thyrotoxicosis factitia
0.000 0.361 0.638
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.361 0.638
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.361 0.638
K83.1 Obstruction of bile duct
0.637 0.363 0.000
T95 Sequelae of burns, corrosions and frostbite
0.637 0.363 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.637 0.363 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.637 0.363 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.637 0.363 0.000
T50.8 Diagnostic agents
0.637 0.363 0.000
T50.7 Analeptics and opioid receptor antagonists
0.637 0.363 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.637 0.363 0.000
T50.5 Appetite depressants
0.637 0.363 0.000
T50.4 Drugs affecting uric acid metabolism
0.637 0.363 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.637 0.363 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.637 0.363 0.000
T50.1 Loop [high-ceiling] diuretics
0.637 0.363 0.000
T50.0 Mineralocorticoids and their antagonists
0.637 0.363 0.000
K70.3 Alcoholic cirrhosis of liver
0.636 0.364 0.000
X60-X84 Intentional self-harm
0.636 0.364 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.636 0.364 0.000
G24.4 Idiopathic orofacial dystonia
0.635 0.365 0.000
G24.2 Idiopathic nonfamilial dystonia
0.635 0.365 0.000
G24.1 Idiopathic familial dystonia
0.635 0.365 0.000
G24.0 Drug-induced dystonia
0.635 0.365 0.000
K70.1 Alcoholic hepatitis
0.634 0.366 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.634 0.366 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.634 0.366 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.634 0.366 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.634 0.366 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.634 0.366 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.634 0.366 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.634 0.366 0.000
T44.0 Anticholinesterase agents
0.634 0.366 0.000
G41 Status epilepticus
0.634 0.366 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.631 0.369 0.000
S37 Injury of urinary and pelvic organs
0.631 0.369 0.000
S36 Injury of intra-abdominal organs
0.631 0.369 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.631 0.369 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.631 0.369 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.631 0.369 0.000
G90-G99 Other disorders of the nervous system
0.630 0.370 0.000
L20-L30 Dermatitis and eczema
0.627 0.373 0.000
J37.0 Chronic laryngitis
0.000 0.373 0.627
M60-M63 Disorders of muscles
0.625 0.375 0.000
J32.2 Chronic ethmoidal sinusitis
0.000 0.375 0.625
F12 Mental and behavioural disorders due to use of cannabinoids
0.624 0.376 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.622 0.378 0.000
Q55 Other congenital malformations of male genital organs
0.622 0.378 0.000
Q53 Undescended testicle
0.622 0.378 0.000
Q52 Other congenital malformations of female genitalia
0.622 0.378 0.000
N11 Chronic tubulo-interstitial nephritis
0.622 0.378 0.000
E10.5 With peripheral circulatory complications
0.000 0.380 0.620
S79.9 Unspecified injury of hip and thigh
0.618 0.382 0.000
S19 Other and unspecified injuries of neck
0.618 0.382 0.000
F30.8 Other manic episodes
0.618 0.382 0.000
F30.2 Mania with psychotic symptoms
0.618 0.382 0.000
F30.1 Mania without psychotic symptoms
0.618 0.382 0.000
Q83 Congenital malformations of breast
0.618 0.382 0.000
N62 Hypertrophy of breast
0.617 0.383 0.000
J35 Chronic diseases of tonsils and adenoids
0.000 0.384 0.616
Q82 Other congenital malformations of skin
0.615 0.385 0.000
E10.7 With multiple complications
0.000 0.386 0.614
E10.6 With other specified complications
0.000 0.386 0.614
E10.0 With coma
0.000 0.386 0.614
M12 Other specific arthropathies
0.614 0.386 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.614 0.386 0.000
M08 Juvenile arthritis
0.614 0.386 0.000
G11 Hereditary ataxia
0.614 0.386 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.614 0.386 0.000
N64 Other disorders of breast
0.613 0.387 0.000
J45.0 Predominantly allergic asthma
0.000 0.388 0.612
Q28 Other congenital malformations of circulatory system
0.610 0.390 0.000
Q27 Other congenital malformations of peripheral vascular system
0.610 0.390 0.000
Q26 Congenital malformations of great veins
0.610 0.390 0.000
Q25 Congenital malformations of great arteries
0.610 0.390 0.000
Q24 Other congenital malformations of heart
0.610 0.390 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.610 0.390 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.610 0.390 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.390 0.610
G40.8 Other epilepsy
0.609 0.391 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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