TreeWAS – Variant ID: rs9461755

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.001	0.999
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
J45 Asthma	0.000	0.001	0.999
J40-J47 Chronic lower respiratory diseases	0.000	0.001	0.999
M06.9 Rheumatoid arthritis, unspecified	0.000	0.001	0.999
# Top node	0.001	0.002	0.998
K90 Intestinal malabsorption	0.000	0.002	0.998
Chapter X Diseases of the respiratory system	0.000	0.002	0.998
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.002	0.998
K90-K93 Other diseases of the digestive system	0.000	0.002	0.998
Chapter XI Diseases of the digestive system	0.000	0.002	0.997
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.003	0.997
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.003	0.997
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.010	0.990
Chapter II Neoplasms	0.000	0.011	0.989
K20-K31 Diseases of oesophagus, stomach and duodenum	0.000	0.012	0.988
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.014	0.986
C44 Other malignant neoplasms of skin	0.000	0.015	0.985
J44 Other chronic obstructive pulmonary disease	0.000	0.020	0.980
C44.3 Skin of other and unspecified parts of face	0.000	0.020	0.980
K29 Gastritis and duodenitis	0.000	0.022	0.978
K29.8 Duodenitis	0.000	0.026	0.974
D60-D64 Aplastic and other anaemias	0.000	0.026	0.974
D64 Other anaemias	0.000	0.036	0.964
D64.9 Anaemia, unspecified	0.000	0.042	0.958
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.045	0.955
C44.7 Skin of lower limb, including hip	0.000	0.047	0.953
M06 Other rheumatoid arthritis	0.014	0.048	0.937
K20 Oesophagitis	0.000	0.060	0.940
J00-J06 Acute upper respiratory infections	0.000	0.066	0.934
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.081	0.919
J20-J22 Other acute lower respiratory infections	0.000	0.087	0.913
M05-M14 Inflammatory polyarthropathies	0.072	0.092	0.836
E05.9 Thyrotoxicosis, unspecified	0.000	0.092	0.908
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.094	0.906
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.102	0.095	0.803
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.105	0.895
K22 Other diseases of oesophagus	0.000	0.110	0.890
J46 Status asthmaticus	0.000	0.111	0.889
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.120	0.880
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	0.120	0.880
D00-D09 In situ neoplasms	0.000	0.121	0.879
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.122	0.878
K29.4 Chronic atrophic gastritis	0.000	0.125	0.875
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.138	0.862
J02 Acute pharyngitis	0.000	0.141	0.859
J22 Unspecified acute lower respiratory infection	0.000	0.141	0.859
K22.2 Oesophageal obstruction	0.000	0.142	0.858
C44.0 Skin of lip	0.000	0.143	0.857
K70-K77 Diseases of liver	0.000	0.143	0.857
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.000	0.144	0.856
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.150	0.850
M80-M85 Disorders of bone density and structure	0.082	0.151	0.766
D06 Carcinoma in situ of cervix uteri	0.000	0.152	0.848
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.152	0.848
C51-C58 Malignant neoplasms of female genital organs	0.000	0.157	0.843
E10-E14 Diabetes mellitus	0.000	0.158	0.842
E50-E64 Other nutritional deficiencies	0.000	0.166	0.833
E06 Thyroiditis	0.000	0.173	0.827
D06.9 Cervix, unspecified	0.000	0.174	0.826
K92 Other diseases of digestive system	0.000	0.177	0.823
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.000	0.179	0.820
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.189	0.811
M06.0 Seronegative rheumatoid arthritis	0.008	0.189	0.804
J02.9 Acute pharyngitis, unspecified	0.000	0.194	0.806
E11 Non-insulin-dependent diabetes mellitus	0.000	0.195	0.805
D69 Purpura and other haemorrhagic conditions	0.000	0.197	0.803
M81 Osteoporosis without pathological fracture	0.042	0.199	0.758
L40-L45 Papulosquamous disorders	0.000	0.200	0.800
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.204	0.796
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.205	0.795
K70 Alcoholic liver disease	0.000	0.205	0.795
E11.3 With ophthalmic complications	0.000	0.211	0.789
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.212	0.788
K35-K38 Diseases of appendix	0.000	0.218	0.782
L57 Skin changes due to chronic exposure to nonionising radiation	0.000	0.222	0.778
D80-D89 Certain disorders involving the immune mechanism	0.000	0.224	0.776
K22.1 Ulcer of oesophagus	0.000	0.230	0.770
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.231	0.769
M81.9 Osteoporosis, unspecified	0.013	0.232	0.755
D45 Polycythaemia vera	0.000	0.235	0.765
K92.0 Haematemesis	0.000	0.238	0.762
C73 Malignant neoplasm of thyroid gland	0.000	0.239	0.761
D69.6 Thrombocytopenia, unspecified	0.000	0.240	0.760
L57.0 Actinic keratosis	0.000	0.240	0.760
K29.1 Other acute gastritis	0.000	0.242	0.758
K27 Peptic ulcer, site unspecified	0.000	0.242	0.757
K29.5 Chronic gastritis, unspecified	0.000	0.246	0.754
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.246	0.753
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.249	0.751
D62 Acute posthaemorrhagic anaemia	0.000	0.249	0.751
K26 Duodenal ulcer	0.000	0.252	0.748
L40 Psoriasis	0.000	0.253	0.747
C53 Malignant neoplasm of cervix uteri	0.000	0.254	0.746
M05 Seropositive rheumatoid arthritis	0.042	0.255	0.703
K70.9 Alcoholic liver disease, unspecified	0.000	0.261	0.739
Chapter I Certain infectious and parasitic diseases	0.000	0.264	0.736
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.265	0.735
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.268	0.732
E55 Vitamin D deficiency	0.000	0.269	0.730
C54 Malignant neoplasm of corpus uteri	0.000	0.271	0.729
E20-E35 Disorders of other endocrine glands	0.000	0.278	0.722
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.278	0.722
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.280	0.720
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.282	0.718
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.716
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.716
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.283	0.716
J45.8 Mixed asthma	0.000	0.284	0.716
J45.1 Nonallergic asthma	0.000	0.284	0.716
J41 Simple and mucopurulent chronic bronchitis	0.000	0.284	0.716
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.284	0.716
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.284	0.716
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.284	0.716
Chapter XVI Certain conditions originating in the perinatal period	0.001	0.284	0.715
K90.8 Other intestinal malabsorption	0.000	0.284	0.716
K90.3 Pancreatic steatorrhoea	0.000	0.284	0.716
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.284	0.716
K90.1 Tropical sprue	0.000	0.284	0.716
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.285	0.715
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.000	0.286	0.714
E07 Other disorders of thyroid	0.000	0.289	0.711
J03 Acute tonsillitis	0.000	0.289	0.711
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.003	0.289	0.707
J01 Acute sinusitis	0.000	0.290	0.710
C40-C41 Malignant neoplasms of bone and articular cartilage	0.000	0.291	0.709
K22.9 Disease of oesophagus, unspecified	0.000	0.291	0.709
K28 Gastrojejunal ulcer	0.000	0.292	0.708
K23 Disorders of oesophagus in diseases classified elsewhere	0.000	0.292	0.708
K92.1 Melaena	0.000	0.292	0.708
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.293	0.707
C44.8 Overlapping lesion of skin	0.000	0.293	0.706
C44.4 Skin of scalp and neck	0.000	0.294	0.706
J45.0 Predominantly allergic asthma	0.000	0.294	0.706
D55-D59 Haemolytic anaemias	0.000	0.294	0.706
B35-B49 Mycoses	0.000	0.296	0.704
E06.3 Autoimmune thyroiditis	0.000	0.297	0.703
E11.4 With neurological complications	0.000	0.297	0.703
K29.9 Gastroduodenitis, unspecified	0.000	0.299	0.701
K29.2 Alcoholic gastritis	0.000	0.299	0.701
J06 Acute upper respiratory infections of multiple and unspecified sites	0.000	0.299	0.700
Chapter XXII Codes for special purposes	0.001	0.300	0.699
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.302	0.698
D64.8 Other specified anaemias	0.000	0.308	0.691
D64.4 Congenital dyserythropoietic anaemia	0.000	0.308	0.691
D64.3 Other sideroblastic anaemias	0.000	0.308	0.691
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.308	0.691
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.308	0.691
D64.0 Hereditary sideroblastic anaemia	0.000	0.308	0.691
L40.9 Psoriasis, unspecified	0.000	0.309	0.691
J95-J99 Other diseases of the respiratory system	0.000	0.309	0.690
C81 Hodgkin's disease	0.000	0.313	0.687
K29.3 Chronic superficial gastritis	0.000	0.314	0.686
L80-L99 Other disorders of the skin and subcutaneous tissue	0.000	0.315	0.685
E05.8 Other thyrotoxicosis	0.000	0.315	0.685
E05.5 Thyroid crisis or storm	0.000	0.315	0.685
E05.4 Thyrotoxicosis factitia	0.000	0.315	0.685
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.315	0.685
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.315	0.685
B37 Candidiasis	0.000	0.317	0.683
M06.8 Other specified rheumatoid arthritis	0.010	0.318	0.672
M06.4 Inflammatory polyarthropathy	0.010	0.318	0.672
M06.3 Rheumatoid nodule	0.010	0.318	0.672
M06.2 Rheumatoid bursitis	0.010	0.318	0.672
M06.1 Adult-onset Still's disease	0.010	0.318	0.672
J04 Acute laryngitis and tracheitis	0.000	0.318	0.682
C53.9 Cervix uteri, unspecified	0.000	0.324	0.676
C44.1 Skin of eyelid, including canthus	0.000	0.329	0.671
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.000	0.331	0.669
L82 Seborrhoeic keratosis	0.000	0.331	0.669
E03.8 Other specified hypothyroidism	0.000	0.334	0.666
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.334	0.665
C09 Malignant neoplasm of tonsil	0.000	0.336	0.664
D75 Other diseases of blood and blood-forming organs	0.000	0.337	0.663
C60-C63 Malignant neoplasms of male genital organs	0.000	0.338	0.662
J00 Acute nasopharyngitis [common cold]	0.000	0.339	0.661
C44.5 Skin of trunk	0.000	0.339	0.661
M07 Psoriatic and enteropathic arthropathies	0.048	0.343	0.609
E55.9 Vitamin D deficiency, unspecified	0.000	0.343	0.657
M91-M94 Chondropathies	0.068	0.344	0.589
K72 Hepatic failure, not elsewhere classified	0.000	0.345	0.655
J21 Acute bronchiolitis	0.000	0.346	0.654
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.347	0.653
M14 Arthropathies in other diseases classified elsewhere	0.052	0.349	0.600
M12 Other specific arthropathies	0.052	0.349	0.600
M09 Juvenile arthritis in diseases classified elsewhere	0.052	0.349	0.600
M08 Juvenile arthritis	0.052	0.349	0.600
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.351	0.649
B37.8 Candidiasis of other sites	0.000	0.352	0.648
C54.1 Endometrium	0.000	0.353	0.647
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.353	0.646
K90.9 Intestinal malabsorption, unspecified	0.000	0.355	0.645
K22.8 Other specified diseases of oesophagus	0.000	0.355	0.644
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.356	0.644
D86 Sarcoidosis	0.000	0.356	0.644
K65-K67 Diseases of peritoneum	0.000	0.356	0.644
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.358	0.642
C95 Leukaemia of unspecified cell type	0.000	0.358	0.642
C94 Other leukaemias of specified cell type	0.000	0.358	0.642
C93 Monocytic leukaemia	0.000	0.358	0.642
C86 Other specified types of T/NK-cell lymphoma	0.000	0.358	0.642
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.358	0.642
K22.4 Dyskinesia of oesophagus	0.000	0.359	0.640
K22.3 Perforation of oesophagus	0.000	0.361	0.638
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.000	0.363	0.637
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.364	0.636
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.365	0.635
C44.2 Skin of ear and external auricular canal	0.000	0.365	0.635
D05 Carcinoma in situ of breast	0.000	0.366	0.634
C64-C68 Malignant neoplasms of urinary tract	0.000	0.366	0.634
D67 Hereditary factor IX deficiency	0.000	0.369	0.631
D66 Hereditary factor VIII deficiency	0.000	0.369	0.631
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.369	0.631
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.369	0.631
L10-L14 Bullous disorders	0.000	0.369	0.631
C92 Myeloid leukaemia	0.000	0.369	0.631
D02 Carcinoma in situ of middle ear and respiratory system	0.000	0.370	0.630
D01 Carcinoma in situ of other and unspecified digestive organs	0.000	0.370	0.630
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.000	0.370	0.630
M05.9 Seropositive rheumatoid arthritis, unspecified	0.020	0.371	0.608
A50-A64 Infections with a predominantly sexual mode of transmission	0.000	0.372	0.628
D68 Other coagulation defects	0.000	0.373	0.627
E53 Deficiency of other B group vitamins	0.000	0.374	0.626
M00-M03 Infectious arthropathies	0.076	0.376	0.548
D47.2 Monoclonal gammopathy	0.000	0.376	0.624
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.377	0.622
K37 Unspecified appendicitis	0.000	0.378	0.622
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.379	0.621
J20 Acute bronchitis	0.000	0.380	0.620
Z85 Personal history of malignant neoplasm	0.000	0.380	0.620
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.381	0.619
C91 Lymphoid leukaemia	0.000	0.381	0.618
K31 Other diseases of stomach and duodenum	0.000	0.382	0.617
M11 Other crystal arthropathies	0.052	0.383	0.565
J02.8 Acute pharyngitis due to other specified organisms	0.000	0.384	0.616
J02.0 Streptococcal pharyngitis	0.000	0.384	0.616
E11.5 With peripheral circulatory complications	0.000	0.385	0.615
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.385	0.615
K77 Liver disorders in diseases classified elsewhere	0.000	0.385	0.614
K73 Chronic hepatitis, not elsewhere classified	0.000	0.385	0.614
K71 Toxic liver disease	0.000	0.385	0.614
C75 Malignant neoplasm of other endocrine glands and related structures	0.000	0.386	0.614
C74 Malignant neoplasm of adrenal gland	0.000	0.386	0.614
E04 Other non-toxic goitre	0.000	0.386	0.614
M81.98 Osteoporosis, unspecified (Other)	0.007	0.387	0.607
M60-M63 Disorders of muscles	0.078	0.387	0.535
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.000	0.387	0.613
L00-L08 Infections of the skin and subcutaneous tissue	0.000	0.388	0.612
C51 Malignant neoplasm of vulva	0.000	0.390	0.610
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.390	0.610
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.390	0.609
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.390	0.609
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.390	0.609
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.390	0.609
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.390	0.609
D46 Myelodysplastic syndromes	0.000	0.391	0.609
M83 Adult osteomalacia	0.059	0.391	0.549
M82 Osteoporosis in diseases classified elsewhere	0.059	0.391	0.549
D06.7 Other parts of cervix	0.000	0.392	0.608
D06.1 Exocervix	0.000	0.392	0.608
D06.0 Endocervix	0.000	0.392	0.608
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.393	0.607
C57 Malignant neoplasm of other and unspecified female genital organs	0.000	0.396	0.604
C58 Malignant neoplasm of placenta	0.000	0.396	0.604
C55 Malignant neoplasm of uterus, part unspecified	0.000	0.396	0.604
C52 Malignant neoplasm of vagina	0.000	0.396	0.604
E12 Malnutrition-related diabetes mellitus	0.000	0.396	0.604
C88 Malignant immunoproliferative diseases	0.000	0.396	0.604
K70.4 Alcoholic hepatic failure	0.000	0.397	0.603
K50-K52 Noninfective enteritis and colitis	0.021	0.398	0.581
L40.5 Arthropathic psoriasis	0.000	0.401	0.599
K70.3 Alcoholic cirrhosis of liver	0.000	0.401	0.598
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.402	0.598
E63 Other nutritional deficiencies	0.000	0.402	0.598
E56 Other vitamin deficiencies	0.000	0.402	0.598
E51 Thiamine deficiency	0.000	0.402	0.598
E50 Vitamin A deficiency	0.000	0.402	0.598
E60 Dietary zinc deficiency	0.000	0.402	0.598
E59 Dietary selenium deficiency	0.000	0.402	0.598
E58 Dietary calcium deficiency	0.000	0.402	0.598
E54 Ascorbic acid deficiency	0.000	0.402	0.598
E52 Niacin deficiency [pellagra]	0.000	0.402	0.598
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.403	0.597
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.403	0.597
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.403	0.597
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.407	0.593
E06.9 Thyroiditis, unspecified	0.000	0.407	0.593
E06.5 Other chronic thyroiditis	0.000	0.407	0.593
E06.4 Drug-induced thyroiditis	0.000	0.407	0.593
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.407	0.593
E06.1 Subacute thyroiditis	0.000	0.407	0.593
E06.0 Acute thyroiditis	0.000	0.407	0.593
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.408	0.592
J90-J94 Other diseases of pleura	0.000	0.408	0.592
D75.1 Secondary polycythaemia	0.000	0.410	0.590
K92.8 Other specified diseases of digestive system	0.000	0.410	0.590
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.000	0.412	0.588
L58 Radiodermatitis	0.000	0.412	0.588
L56 Other acute skin changes due to ultraviolet radiation	0.000	0.412	0.588
L55 Sunburn	0.000	0.412	0.588
K35 Acute appendicitis	0.000	0.416	0.584
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.005	0.416	0.579
D09 Carcinoma in situ of other and unspecified sites	0.000	0.417	0.583
E40-E46 Malnutrition	0.000	0.417	0.582
E11.6 With other specified complications	0.000	0.418	0.582
D50-D53 Nutritional anaemias	0.000	0.418	0.582
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.418	0.582
C82.6 Cutaneous follicle centre lymphoma	0.000	0.418	0.582
C82.5 Diffuse follicle centre lymphoma	0.000	0.418	0.582
C82.4 Follicular lymphoma grade IIIb	0.000	0.418	0.582
C82.3 Follicular lymphoma grade IIIa	0.000	0.418	0.582
C82.2 Large cell, follicular	0.000	0.418	0.582
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.418	0.582
C82.0 Small cleaved cell, follicular	0.000	0.418	0.582
M06.08 Seronegative rheumatoid arthritis (Other)	0.006	0.418	0.576
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.006	0.418	0.576
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.006	0.418	0.576
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.006	0.418	0.576
M06.04 Seronegative rheumatoid arthritis (Hand)	0.006	0.418	0.576
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.006	0.418	0.576
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.006	0.418	0.576
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.006	0.418	0.576
K76 Other diseases of liver	0.000	0.418	0.582
C85.1 B-cell lymphoma, unspecified	0.000	0.421	0.579
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.421	0.578
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.422	0.578
E29 Testicular dysfunction	0.000	0.423	0.577
E11.8 With unspecified complications	0.000	0.423	0.577
E11.7 With multiple complications	0.000	0.423	0.577
B37.0 Candidal stomatitis	0.000	0.424	0.576
J60-J70 Lung diseases due to external agents	0.000	0.424	0.575
M40-M43 Deforming dorsopathies	0.069	0.424	0.507
D69.9 Haemorrhagic condition, unspecified	0.000	0.424	0.576
D69.8 Other specified haemorrhagic conditions	0.000	0.424	0.576
D69.4 Other primary thrombocytopenia	0.000	0.424	0.576
D69.2 Other nonthrombocytopenic purpura	0.000	0.424	0.576
D69.1 Qualitative platelet defects	0.000	0.424	0.576
D69.0 Allergic purpura	0.000	0.424	0.576
E21.0 Primary hyperparathyroidism	0.000	0.425	0.575
M81.8 Other osteoporosis	0.030	0.426	0.544
M81.6 Localised osteoporosis [Lequesne]	0.030	0.426	0.544
M81.5 Idiopathic osteoporosis	0.030	0.426	0.544
M81.3 Postsurgical malabsorption osteoporosis	0.030	0.426	0.544
M81.2 Osteoporosis of disuse	0.030	0.426	0.544
M81.1 Postoophorectomy osteoporosis	0.030	0.426	0.544
M81.0 Postmenopausal osteoporosis	0.030	0.426	0.544
L44 Other papulosquamous disorders	0.000	0.427	0.573
L41 Parapsoriasis	0.000	0.427	0.573
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.427	0.573
L42 Pityriasis rosea	0.000	0.427	0.573
M80 Osteoporosis with pathological fracture	0.057	0.427	0.516
M10 Gout	0.042	0.429	0.529
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.000	0.430	0.570
C13 Malignant neoplasm of hypopharynx	0.000	0.430	0.570
C11 Malignant neoplasm of nasopharynx	0.000	0.430	0.570
C10 Malignant neoplasm of oropharynx	0.000	0.430	0.570
C08 Malignant neoplasm of other and unspecified major salivary glands	0.000	0.430	0.570
C06 Malignant neoplasm of other and unspecified parts of mouth	0.000	0.430	0.570
C05 Malignant neoplasm of palate	0.000	0.430	0.570
C04 Malignant neoplasm of floor of mouth	0.000	0.430	0.570
C03 Malignant neoplasm of gum	0.000	0.430	0.570
C00 Malignant neoplasm of lip	0.000	0.430	0.570
C12 Malignant neoplasm of pyriform sinus	0.000	0.430	0.570
C07 Malignant neoplasm of parotid gland	0.000	0.430	0.570
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.430	0.570
K70.0 Alcoholic fatty liver	0.000	0.430	0.570
C09.9 Tonsil, unspecified	0.000	0.430	0.570
K26.4 Chronic or unspecified with haemorrhage	0.000	0.433	0.567
K29.0 Acute haemorrhagic gastritis	0.000	0.434	0.566
D68.9 Coagulation defect, unspecified	0.000	0.435	0.564
B07 Viral warts	0.000	0.435	0.565
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.436	0.564
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.076	0.436	0.488
B90-B94 Sequelae of infectious and parasitic diseases	0.000	0.439	0.561
K36 Other appendicitis	0.000	0.439	0.561
M85 Other disorders of bone density and structure	0.060	0.441	0.499
K75 Other inflammatory liver diseases	0.000	0.441	0.559
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.000	0.442	0.558
L57.5 Actinic granuloma	0.000	0.442	0.558
L57.4 Cutis laxa senilis	0.000	0.442	0.558
L57.3 Poikiloderma of Civatte	0.000	0.442	0.558
L57.2 Cutis rhomboidalis nuchae	0.000	0.442	0.558
L57.1 Actinic reticuloid	0.000	0.442	0.558
D84 Other immunodeficiencies	0.000	0.443	0.556
D83 Common variable immunodeficiency	0.000	0.443	0.556
D82 Immunodeficiency associated with other major defects	0.000	0.443	0.556
D81 Combined immunodeficiencies	0.000	0.443	0.556
D80 Immunodeficiency with predominantly antibody defects	0.000	0.443	0.556
D72 Other disorders of white blood cells	0.000	0.444	0.555
Z85.4 Personal history of malignant neoplasm of genital organs	0.000	0.445	0.555
L43 Lichen planus	0.000	0.446	0.554
E11.0 With coma	0.000	0.446	0.554
L97 Ulcer of lower limb, not elsewhere classified	0.000	0.447	0.553
K70.1 Alcoholic hepatitis	0.000	0.447	0.553
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.448	0.552
D74 Methaemoglobinaemia	0.000	0.448	0.552
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.448	0.552
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.448	0.552
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.448	0.552
J03.9 Acute tonsillitis, unspecified	0.000	0.449	0.551
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.010	0.449	0.541
M81.96 Osteoporosis, unspecified (Lower leg)	0.010	0.449	0.541
M81.94 Osteoporosis, unspecified (Hand)	0.010	0.449	0.541
M81.93 Osteoporosis, unspecified (Forearm)	0.010	0.449	0.541
M81.92 Osteoporosis, unspecified (Upper arm)	0.010	0.449	0.541
M81.91 Osteoporosis, unspecified (Shoulder region)	0.010	0.449	0.541
K22.5 Diverticulum of oesophagus, acquired	0.000	0.450	0.550
K22.0 Achalasia of cardia	0.000	0.451	0.549
J01.9 Acute sinusitis, unspecified	0.000	0.451	0.549
D61 Other aplastic anaemias	0.000	0.451	0.549
E13 Other specified diabetes mellitus	0.000	0.452	0.547
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.453	0.547
M81.4 Drug-induced osteoporosis	0.031	0.454	0.516
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.455	0.545
K38 Other diseases of appendix	0.000	0.456	0.544
L08 Other local infections of skin and subcutaneous tissue	0.000	0.456	0.544
E07.9 Disorder of thyroid, unspecified	0.000	0.456	0.544
L40.0 Psoriasis vulgaris	0.000	0.456	0.543
K27.7 Chronic without haemorrhage or perforation	0.000	0.457	0.543
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.457	0.543
K27.5 Chronic or unspecified with perforation	0.000	0.457	0.543
K27.4 Chronic or unspecified with haemorrhage	0.000	0.457	0.543
K27.3 Acute without haemorrhage or perforation	0.000	0.457	0.543
K27.2 Acute with both haemorrhage and perforation	0.000	0.457	0.543
K27.1 Acute with perforation	0.000	0.457	0.543
K27.0 Acute with haemorrhage	0.000	0.457	0.543
L50-L54 Urticaria and erythema	0.000	0.457	0.543
D04 Carcinoma in situ of skin	0.000	0.457	0.542
E14 Unspecified diabetes mellitus	0.000	0.459	0.541
K51 Ulcerative colitis	0.008	0.462	0.530
C81.9 Hodgkin's disease, unspecified	0.000	0.463	0.537
D86.0 Sarcoidosis of lung	0.000	0.463	0.537
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.463	0.537
K26.2 Acute with both haemorrhage and perforation	0.000	0.463	0.537
K26.1 Acute with perforation	0.000	0.463	0.537
K26.0 Acute with haemorrhage	0.000	0.463	0.537
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.009	0.464	0.527
L40.8 Other psoriasis	0.000	0.464	0.535
L40.4 Guttate psoriasis	0.000	0.464	0.535
L40.3 Pustulosis palmaris et plantaris	0.000	0.464	0.535
L40.2 Acrodermatitis continua	0.000	0.464	0.535
L40.1 Generalised pustular psoriasis	0.000	0.464	0.535
C67 Malignant neoplasm of bladder	0.000	0.465	0.535
B25-B34 Other viral diseases	0.000	0.465	0.535
C53.8 Overlapping lesion of cervix uteri	0.000	0.465	0.535
C53.1 Exocervix	0.000	0.465	0.535
C53.0 Endocervix	0.000	0.465	0.535
M05.8 Other seropositive rheumatoid arthritis	0.030	0.465	0.504
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.030	0.465	0.504
M05.2 Rheumatoid vasculitis	0.030	0.465	0.504
M05.1 Rheumatoid lung disease	0.030	0.465	0.504
M05.0 Felty's syndrome	0.030	0.465	0.504
J06.9 Acute upper respiratory infection, unspecified	0.000	0.466	0.533
B20-B24 Human immunodeficiency virus [HIV] disease	0.000	0.467	0.533
J95.8 Other postprocedural respiratory disorders	0.000	0.469	0.531
D63.0 Anaemia in neoplastic disease	0.000	0.470	0.530
B35 Dermatophytosis	0.000	0.470	0.530
D70 Agranulocytosis	0.000	0.472	0.528
B99-B99 Other infectious diseases	0.000	0.472	0.527
B85-B89 Pediculosis, acariasis and other infestations	0.000	0.472	0.527
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.000	0.472	0.527
A75-A79 Rickettsioses	0.000	0.472	0.527
A70-A74 Other diseases caused by chlamydiae	0.000	0.472	0.527
A65-A69 Other spirochaetal diseases	0.000	0.472	0.527
A20-A28 Certain zoonotic bacterial diseases	0.000	0.472	0.527
A15-A19 Tuberculosis	0.000	0.472	0.527
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.473	0.527
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.473	0.527
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.473	0.527
D47.4 Osteomyelofibrosis	0.000	0.473	0.527
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.473	0.527
C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.473	0.527
E61 Deficiency of other nutrient elements	0.000	0.473	0.527
C01 Malignant neoplasm of base of tongue	0.000	0.475	0.525
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.475	0.525
C85.0 Lymphosarcoma	0.000	0.475	0.525
C50-C50 Malignant neoplasm of breast	0.000	0.475	0.524
E23 Hypofunction and other disorders of pituitary gland	0.000	0.476	0.524
C44.6 Skin of upper limb, including shoulder	0.000	0.476	0.524
E55.0 Rickets, active	0.000	0.476	0.524
C54.9 Corpus uteri, unspecified	0.000	0.478	0.522
C54.8 Overlapping lesion of corpus uteri	0.000	0.478	0.522
C54.3 Fundus uteri	0.000	0.478	0.522
C54.2 Myometrium	0.000	0.478	0.522
C54.0 Isthmus uteri	0.000	0.478	0.522
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.479	0.521
K26.7 Chronic without haemorrhage or perforation	0.000	0.480	0.520
K74 Fibrosis and cirrhosis of liver	0.000	0.481	0.519
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.482	0.517
E32 Diseases of thymus	0.000	0.482	0.517
E31 Polyglandular dysfunction	0.000	0.482	0.517

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations