TreeWAS – Variant ID: rs9557207

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.761	0.239
E03 Other hypothyroidism	0.001	0.898	0.101
E03.5 Myxoedema coma	0.001	0.927	0.072
E03.4 Atrophy of thyroid (acquired)	0.001	0.927	0.072
E03.3 Postinfectious hypothyroidism	0.001	0.927	0.072
E03.1 Congenital hypothyroidism without goitre	0.001	0.927	0.072
E03.0 Congenital hypothyroidism with diffuse goitre	0.001	0.927	0.072
K70 Alcoholic liver disease	0.071	0.929	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.929	0.070
E03.8 Other specified hypothyroidism	0.000	0.932	0.067
K70.9 Alcoholic liver disease, unspecified	0.067	0.933	0.000
K70.0 Alcoholic fatty liver	0.067	0.933	0.000
K70.4 Alcoholic hepatic failure	0.066	0.934	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.063	0.937	0.000
K70.3 Alcoholic cirrhosis of liver	0.061	0.939	0.000
E04.2 Non-toxic multinodular goitre	0.057	0.943	0.000
K70.1 Alcoholic hepatitis	0.056	0.944	0.000
E04 Other non-toxic goitre	0.035	0.964	0.001
L90.0 Lichen sclerosus et atrophicus	0.000	0.966	0.034
E04.1 Non-toxic single thyroid nodule	0.030	0.969	0.000
K70-K77 Diseases of liver	0.030	0.970	0.000
K76.8 Other specified diseases of liver	0.028	0.972	0.000
K76 Other diseases of liver	0.028	0.972	0.000
E04.8 Other specified non-toxic goitre	0.025	0.974	0.001
E04.9 Non-toxic goitre, unspecified	0.026	0.974	0.000
E04.0 Non-toxic diffuse goitre	0.025	0.974	0.001
K73 Chronic hepatitis, not elsewhere classified	0.025	0.975	0.000
E00-E07 Disorders of thyroid gland	0.001	0.976	0.022
K71 Toxic liver disease	0.023	0.977	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.022	0.978	0.000
K77 Liver disorders in diseases classified elsewhere	0.022	0.978	0.000
K75 Other inflammatory liver diseases	0.021	0.979	0.000
K76.9 Liver disease, unspecified	0.021	0.979	0.000
K76.6 Portal hypertension	0.021	0.979	0.000
K76.5 Hepatic veno-occlusive disease	0.020	0.980	0.000
K76.4 Peliosis hepatis	0.020	0.980	0.000
K76.3 Infarction of liver	0.020	0.980	0.000
K76.2 Central haemorrhagic necrosis of liver	0.020	0.980	0.000
K76.1 Chronic passive congestion of liver	0.020	0.980	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.980	0.020
K76.7 Hepatorenal syndrome	0.019	0.981	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.981	0.019
K75.0 Abscess of liver	0.019	0.981	0.000
K71.0 Toxic liver disease with cholestasis	0.018	0.982	0.000
E06 Thyroiditis	0.001	0.982	0.017
K73.8 Other chronic hepatitis, not elsewhere classified	0.018	0.982	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.018	0.982	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.018	0.982	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.001	0.983	0.016
E00 Congenital iodine-deficiency syndrome	0.001	0.983	0.016
K73.9 Chronic hepatitis, unspecified	0.017	0.983	0.000
K71.9 Toxic liver disease, unspecified	0.017	0.983	0.000
K71.8 Toxic liver disease with other disorders of liver	0.017	0.983	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.017	0.983	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.017	0.983	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.017	0.983	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.017	0.983	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.017	0.983	0.000
K71.2 Toxic liver disease with acute hepatitis	0.017	0.983	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.017	0.983	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.001	0.984	0.015
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.984	0.016
K77.8 Liver disorders in other diseases classified elsewhere	0.016	0.984	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.015	0.984	0.000
K75.2 Nonspecific reactive hepatitis	0.015	0.984	0.000
K75.1 Phlebitis of portal vein	0.015	0.984	0.000
E05.8 Other thyrotoxicosis	0.000	0.985	0.015
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.985	0.015
K75.8 Other specified inflammatory liver diseases	0.015	0.985	0.000
E06.3 Autoimmune thyroiditis	0.000	0.985	0.014
K75.4 Autoimmune hepatitis	0.014	0.986	0.000
E05.5 Thyroid crisis or storm	0.000	0.986	0.014
E05.4 Thyrotoxicosis factitia	0.000	0.986	0.014
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.986	0.014
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.986	0.014
K72 Hepatic failure, not elsewhere classified	0.014	0.986	0.000
E06.5 Other chronic thyroiditis	0.001	0.987	0.013
E06.4 Drug-induced thyroiditis	0.001	0.987	0.013
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.987	0.013
E06.1 Subacute thyroiditis	0.001	0.987	0.013
E06.0 Acute thyroiditis	0.001	0.987	0.013
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.001	0.987	0.012
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.001	0.987	0.012
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.001	0.987	0.012
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.001	0.987	0.012
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.001	0.987	0.012
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.001	0.987	0.012
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.001	0.987	0.012
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.001	0.987	0.012
E06.9 Thyroiditis, unspecified	0.001	0.987	0.012
E07 Other disorders of thyroid	0.001	0.988	0.011
K75.9 Inflammatory liver disease, unspecified	0.011	0.988	0.000
K72.1 Chronic hepatic failure	0.010	0.990	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.990	0.010
E10 Insulin-dependent diabetes mellitus	0.000	0.990	0.010
E10.2 With renal complications	0.000	0.990	0.010
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.991	0.009
E07.1 Dyshormogenetic goitre	0.001	0.991	0.008
E07.0 Hypersecretion of calcitonin	0.001	0.991	0.008
K22.8 Other specified diseases of oesophagus	0.000	0.991	0.009
E10.3 With ophthalmic complications	0.000	0.991	0.009
K76.0 Fatty (change of) liver, not elsewhere classified	0.009	0.991	0.000
K72.9 Hepatic failure, unspecified	0.008	0.991	0.000
E10.4 With neurological complications	0.000	0.992	0.008
E07.8 Other specified disorders of thyroid	0.001	0.992	0.008
E10.8 With unspecified complications	0.000	0.992	0.008
E10.5 With peripheral circulatory complications	0.000	0.992	0.008
E10.1 With ketoacidosis	0.000	0.992	0.008
K51.2 Ulcerative (chronic) proctitis	0.000	0.992	0.008
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.992	0.008
H65.3 Chronic mucoid otitis media	0.008	0.992	0.000
E10.0 With coma	0.000	0.992	0.007
K51.9 Ulcerative colitis, unspecified	0.000	0.992	0.008
K86.0 Alcohol-induced chronic pancreatitis	0.007	0.993	0.000
E10.7 With multiple complications	0.000	0.993	0.007
N42.9 Disorder of prostate, unspecified	0.007	0.993	0.000
E10.6 With other specified complications	0.000	0.993	0.007
E05.9 Thyrotoxicosis, unspecified	0.000	0.993	0.007
E16.2 Hypoglycaemia, unspecified	0.000	0.993	0.007
K86.8 Other specified diseases of pancreas	0.007	0.993	0.000
H65 Nonsuppurative otitis media	0.007	0.993	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.993	0.007
K86 Other diseases of pancreas	0.007	0.993	0.000
H65.2 Chronic serous otitis media	0.007	0.993	0.000
K86.3 Pseudocyst of pancreas	0.006	0.994	0.000
N42.1 Congestion and haemorrhage of prostate	0.006	0.994	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.994	0.006
K51 Ulcerative colitis	0.000	0.994	0.006
M54.59 Low back pain (Site unspecified)	0.000	0.994	0.006
L90 Atrophic disorders of skin	0.000	0.994	0.006
K74 Fibrosis and cirrhosis of liver	0.006	0.994	0.000
K91.1 Postgastric surgery syndromes	0.000	0.994	0.006
H65.4 Other chronic nonsuppurative otitis media	0.006	0.994	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.994	0.006
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.994	0.006
H65.1 Other acute nonsuppurative otitis media	0.006	0.994	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.994	0.005
K91.5 Postcholecystectomy syndrome	0.000	0.994	0.005
E07.9 Disorder of thyroid, unspecified	0.001	0.994	0.005
K72.0 Acute and subacute hepatic failure	0.005	0.995	0.001
K91.4 Colostomy and enterostomy malfunction	0.000	0.995	0.005
K51.4 Pseudopolyposis of colon	0.000	0.995	0.005
N42 Other disorders of prostate	0.005	0.995	0.000
A04.8 Other specified bacterial intestinal infections	0.000	0.995	0.005
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.995	0.005
A04 Other bacterial intestinal infections	0.000	0.995	0.005
K86.9 Disease of pancreas, unspecified	0.005	0.995	0.000
H65.0 Acute serous otitis media	0.005	0.995	0.000
E40-E46 Malnutrition	0.000	0.995	0.005
H65.9 Nonsuppurative otitis media, unspecified	0.005	0.995	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.995	0.005
E10-E14 Diabetes mellitus	0.000	0.995	0.005
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.995	0.005
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.995	0.005
S56.7 Injury of multiple muscles and tendons at forearm level	0.005	0.995	0.000
N72 Inflammatory disease of cervix uteri	0.005	0.995	0.000
S56 Injury of muscle and tendon at forearm level	0.005	0.995	0.000
E16.1 Other hypoglycaemia	0.000	0.995	0.005
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.995	0.005
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.995	0.005
E16.4 Abnormal secretion of gastrin	0.000	0.995	0.005
E16.3 Increased secretion of glucagon	0.000	0.995	0.005
L90.9 Atrophic disorder of skin, unspecified	0.000	0.995	0.005
L90.8 Other atrophic disorders of skin	0.000	0.995	0.005
L90.6 Striae atrophicae	0.000	0.995	0.005
L90.4 Acrodermatitis chronica atrophicans	0.000	0.995	0.005
L90.3 Atrophoderma of Pasini and Pierini	0.000	0.995	0.005
L90.2 Anetoderma of Jadassohn-Pellizzari	0.000	0.995	0.005
L90.1 Anetoderma of Schweninger-Buzzi	0.000	0.995	0.005
K74.4 Secondary biliary cirrhosis	0.004	0.995	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.004	0.995	0.000
K74.1 Hepatic sclerosis	0.004	0.995	0.000
K86.1 Other chronic pancreatitis	0.005	0.995	0.000
K86.2 Cyst of pancreas	0.005	0.995	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.005	0.995	0.000
E10.9 Without complications	0.000	0.995	0.005
K51.8 Other ulcerative colitis	0.000	0.995	0.004
N42.2 Atrophy of prostate	0.004	0.995	0.000
K74.5 Biliary cirrhosis, unspecified	0.004	0.996	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.004	0.996	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.996	0.004
E15 Nondiabetic hypoglycaemic coma	0.000	0.996	0.004
A04.9 Bacterial intestinal infection, unspecified	0.000	0.996	0.004
T82.1 Mechanical complication of cardiac electronic device	0.000	0.996	0.004
K04.8 Radicular cyst	0.004	0.996	0.000
A04.5 Campylobacter enteritis	0.000	0.996	0.004
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.996	0.004
N42.3 Dysplasia of prostate	0.004	0.996	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.000	0.996	0.004
A04.3 Enterohaemorrhagic Escherichia coli infection	0.000	0.996	0.004
A04.2 Enteroinvasive Escherichia coli infection	0.000	0.996	0.004
A04.1 Enterotoxigenic Escherichia coli infection	0.000	0.996	0.004
A04.0 Enteropathogenic Escherichia coli infection	0.000	0.996	0.004
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.004	0.996	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.996	0.004
E45 Retarded development following protein-energy malnutrition	0.000	0.996	0.004
E43 Unspecified severe protein-energy malnutrition	0.000	0.996	0.004
E42 Marasmic kwashiorkor	0.000	0.996	0.004
E41 Nutritional marasmus	0.000	0.996	0.004
E40 Kwashiorkor	0.000	0.996	0.004
E12 Malnutrition-related diabetes mellitus	0.000	0.996	0.004
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.004	0.996	0.000
A04.4 Other intestinal Escherichia coli infections	0.000	0.996	0.004
K51.5 Mucosal proctocolitis	0.000	0.996	0.004
S56.2 Injury of other flexor muscle and tendon at forearm level	0.004	0.996	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.004	0.996	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.004	0.996	0.000
N42.0 Calculus of prostate	0.004	0.996	0.000
H66 Suppurative and unspecified otitis media	0.004	0.996	0.000
Q07.0 Arnold-Chiari syndrome	0.004	0.996	0.000
M24.21 Disorder of ligament (Shoulder region)	0.003	0.996	0.000
H66.3 Other chronic suppurative otitis media	0.004	0.996	0.000
M24.2 Disorder of ligament	0.004	0.996	0.000
W25.9 Unspecified place	0.003	0.997	0.000
D10.3 Other and unspecified parts of mouth	0.003	0.997	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.003	0.997	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.003	0.997	0.000
M24.23 Disorder of ligament (Forearm)	0.003	0.997	0.000
W22.9 Unspecified place	0.000	0.997	0.003
H66.9 Otitis media, unspecified	0.003	0.997	0.000
E13 Other specified diabetes mellitus	0.000	0.997	0.003
M24.26 Disorder of ligament (Lower leg)	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
N42.8 Other specified disorders of prostate	0.003	0.997	0.000
Q65.8 Other congenital deformities of hip	0.003	0.997	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.997	0.003
E44.0 Moderate protein-energy malnutrition	0.000	0.997	0.003
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
E12.9 Without complications	0.000	0.997	0.003
E12.8 With unspecified complications	0.000	0.997	0.003
E12.7 With multiple complications	0.000	0.997	0.003
E12.6 With other specified complications	0.000	0.997	0.003
E12.5 With peripheral circulatory complications	0.000	0.997	0.003
E12.4 With neurological complications	0.000	0.997	0.003
E12.3 With ophthalmic complications	0.000	0.997	0.003
E12.2 With renal complications	0.000	0.997	0.003
E12.1 With ketoacidosis	0.000	0.997	0.003
E12.0 With coma	0.000	0.997	0.003
K04.6 Periapical abscess with sinus	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
S51.8 Open wound of other parts of forearm	0.003	0.997	0.000
N48.0 Leukoplakia of penis	0.000	0.997	0.003
H66.2 Chronic atticoantral suppurative otitis media	0.003	0.997	0.000
K74.0 Hepatic fibrosis	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
Q18.1 Preauricular sinus and cyst	0.003	0.997	0.000
M24.51 Contracture of joint (Shoulder region)	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.003	0.997	0.000
H69.8 Other specified disorders of Eustachian tube	0.003	0.997	0.000
S56.20 Unspecified injury of other flexor muscle, fascia and tendon at forearm level	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
H66.0 Acute suppurative otitis media	0.003	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
M24.54 Contracture of joint (Hand)	0.003	0.997	0.000
H66.4 Suppurative otitis media, unspecified	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
M24.5 Contracture of joint	0.003	0.997	0.000
N48.9 Disorder of penis, unspecified	0.000	0.997	0.003
M24.29 Disorder of ligament (Site unspecified)	0.003	0.997	0.000
M24.28 Disorder of ligament (Other)	0.003	0.997	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.003	0.997	0.000
M24.22 Disorder of ligament (Upper arm)	0.003	0.997	0.000
M24.20 Disorder of ligament (Multiple sites)	0.003	0.997	0.000
Q38.7 Pharyngeal pouch	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
O20.0 Threatened abortion	0.003	0.997	0.000
K04 Diseases of pulp and periapical tissues	0.003	0.997	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.997	0.003
K74.6 Other and unspecified cirrhosis of liver	0.003	0.997	0.000
Q66.8 Other congenital deformities of feet	0.003	0.997	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.997	0.003
E13.8 With unspecified complications	0.000	0.997	0.002
E13.7 With multiple complications	0.000	0.997	0.002
E13.6 With other specified complications	0.000	0.997	0.002
E13.5 With peripheral circulatory complications	0.000	0.997	0.002
E13.4 With neurological complications	0.000	0.997	0.002
E13.2 With renal complications	0.000	0.997	0.002
E13.1 With ketoacidosis	0.000	0.997	0.002
E13.0 With coma	0.000	0.997	0.002
H65-H75 Diseases of middle ear and mastoid	0.003	0.997	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.002	0.997	0.000
Q18.8 Other specified congenital malformations of face and neck	0.002	0.997	0.000
Q18.7 Microcheilia	0.002	0.997	0.000
Q18.6 Macrocheilia	0.002	0.997	0.000
Q18.5 Microstomia	0.002	0.997	0.000
Q18.4 Macrostomia	0.002	0.997	0.000
Q18.3 Webbing of neck	0.002	0.997	0.000
Q18.2 Other branchial cleft malformations	0.002	0.997	0.000
Q66.2 Metatarsus varus	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.003	0.997	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.997	0.000
H70 Mastoiditis and related conditions	0.003	0.997	0.000
E13.3 With ophthalmic complications	0.000	0.997	0.002
Q07.9 Congenital malformation of nervous system, unspecified	0.002	0.997	0.000
Q07.8 Other specified congenital malformations of nervous system	0.002	0.997	0.000
H69 Other disorders of Eustachian tube	0.002	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.997	0.000
Q17 Other congenital malformations of ear	0.002	0.997	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.002	0.997	0.000
Q66.0 Talipes equinovarus	0.002	0.997	0.000
Q65.9 Congenital deformity of hip, unspecified	0.002	0.997	0.000
Q65.6 Unstable hip	0.002	0.997	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.997	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.997	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.997	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.997	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.997	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.997	0.000
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
H70.9 Mastoiditis, unspecified	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
S01.3 Open wound of ear	0.000	0.998	0.002
S22.20 Fracture of sternum (closed)	0.000	0.998	0.002
Q43.8 Other specified congenital malformations of intestine	0.002	0.998	0.000
Q03 Congenital hydrocephalus	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
I84.1 Internal haemorrhoids with other complications	0.002	0.998	0.000
L94.0 Localised scleroderma [morphea]	0.002	0.998	0.000
Q66.7 Pes cavus	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
R30.0 Dysuria	0.000	0.998	0.002
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
M24.57 Contracture of joint (Ankle and foot)	0.002	0.998	0.000
K04.5 Chronic apical periodontitis	0.002	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
S51 Open wound of forearm	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.998	0.000
S50-S59 Injuries to the elbow and forearm	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
M24.24 Disorder of ligament (Hand)	0.002	0.998	0.000
M24.59 Contracture of joint (Site unspecified)	0.002	0.998	0.000
M24.58 Contracture of joint (Other)	0.002	0.998	0.000
M24.56 Contracture of joint (Lower leg)	0.002	0.998	0.000
M24.53 Contracture of joint (Forearm)	0.002	0.998	0.000
M24.52 Contracture of joint (Upper arm)	0.002	0.998	0.000
M24.50 Contracture of joint (Multiple sites)	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.998	0.000
Q04 Other congenital malformations of brain	0.002	0.998	0.000
Q01 Encephalocele	0.002	0.998	0.000
Q00 Anencephaly and similar malformations	0.002	0.998	0.000
Q02 Microcephaly	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.002	0.998	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
Q38.8 Other congenital malformations of pharynx	0.002	0.998	0.000
Q38.6 Other congenital malformations of mouth	0.002	0.998	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.002	0.998	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.002	0.998	0.000
Q38.3 Other congenital malformations of tongue	0.002	0.998	0.000
Q38.2 Macroglossia	0.002	0.998	0.000
Q38.1 Ankyloglossia	0.002	0.998	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.002	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
E50-E64 Other nutritional deficiencies	0.000	0.998	0.002
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
K04.3 Abnormal hard tissue formation in pulp	0.002	0.998	0.000
K04.2 Pulp degeneration	0.002	0.998	0.000
K04.1 Necrosis of pulp	0.002	0.998	0.000
Q17.5 Prominent ear	0.002	0.998	0.000
H70.1 Chronic mastoiditis	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
T51.9 Alcohol, unspecified	0.000	0.998	0.002
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
E67 Other hyperalimentation	0.000	0.998	0.002
E68 Sequelae of hyperalimentation	0.000	0.998	0.002
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.998	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H68 Eustachian salpingitis and obstruction	0.002	0.998	0.000
H67 Otitis media in diseases classified elsewhere	0.002	0.998	0.000
E13.9 Without complications	0.000	0.998	0.002
Q03.0 Malformations of aqueduct of Sylvius	0.002	0.998	0.000
Q44.7 Other congenital malformations of liver	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
Q44.4 Choledochal cyst	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.998	0.000
Q44.2 Atresia of bile ducts	0.002	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.998	0.000
E65 Localised adiposity	0.000	0.998	0.002
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
S55 Injury of blood vessels at forearm level	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
Q12 Congenital lens malformations	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
H70.8 Other mastoiditis and related conditions	0.002	0.998	0.000
H70.2 Petrositis	0.002	0.998	0.000
H70.0 Acute mastoiditis	0.002	0.998	0.000
Q43.1 Hirschsprung's disease	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.002	0.998	0.000
H69.0 Patulous Eustachian tube	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
K74.3 Primary biliary cirrhosis	0.002	0.998	0.000
Q17.9 Congenital malformation of ear, unspecified	0.002	0.998	0.000
Q17.8 Other specified congenital malformations of ear	0.002	0.998	0.000
Q17.4 Misplaced ear	0.002	0.998	0.000
Q17.3 Other misshapen ear	0.002	0.998	0.000
Q17.2 Microtia	0.002	0.998	0.000
Q17.1 Macrotia	0.002	0.998	0.000
Q17.0 Accessory auricle	0.002	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.998	0.000
Q45.1 Annular pancreas	0.002	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
K04.0 Pulpitis	0.002	0.998	0.000
K85.1 Biliary acute pancreatitis	0.002	0.998	0.000
S53.0 Dislocation of radial head	0.002	0.998	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.002	0.998	0.000
Q03.8 Other congenital hydrocephalus	0.002	0.998	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
Q43.7 Persistent cloaca	0.002	0.998	0.000
Q43.6 Congenital fistula of rectum and anus	0.002	0.998	0.000
Q43.5 Ectopic anus	0.002	0.998	0.000
Q43.4 Duplication of intestine	0.002	0.998	0.000
Q43.2 Other congenital functional disorders of colon	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.998	0.000
Q68.3 Congenital bowing of femur	0.002	0.998	0.000
Q68.2 Congenital deformity of knee	0.002	0.998	0.000
Q68.1 Congenital deformity of hand	0.002	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.998	0.000
Q69.9 Polydactyly, unspecified	0.002	0.998	0.000
Q69.2 Accessory toe(s)	0.002	0.998	0.000
Q69.1 Accessory thumb(s)	0.002	0.998	0.000
Q69.0 Accessory finger(s)	0.002	0.998	0.000
Q70.9 Syndactyly, unspecified	0.002	0.998	0.000
Q70.4 Polysyndactyly	0.002	0.998	0.000
Q70.3 Webbed toes	0.002	0.998	0.000
Q70.2 Fused toes	0.002	0.998	0.000
Q70.1 Webbed fingers	0.002	0.998	0.000
Q70.0 Fused fingers	0.002	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.998	0.000
Q71.6 Lobster-claw hand	0.002	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.998	0.000
Q72.7 Split foot	0.002	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations