TreeWAS – Variant ID: rs9625963

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
K70-K77 Diseases of liver	1.000	0.000	0.000
I21 Acute myocardial infarction	0.000	0.000	1.000
# Top node	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
K76 Other diseases of liver	1.000	0.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.000	1.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.999	0.001	0.000
T81 Complications of procedures, not elsewhere classified	0.998	0.002	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.002	0.998
Chapter XX External causes of morbidity and mortality	0.998	0.002	0.000
I25.2 Old myocardial infarction	0.000	0.004	0.996
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.004	0.996
K76.0 Fatty (change of) liver, not elsewhere classified	0.995	0.005	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.994	0.006	0.000
I20 Angina pectoris	0.000	0.007	0.993
K70 Alcoholic liver disease	0.992	0.008	0.000
K74 Fibrosis and cirrhosis of liver	0.992	0.008	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.992	0.008	0.000
Chapter XI Diseases of the digestive system	0.989	0.011	0.000
K74.6 Other and unspecified cirrhosis of liver	0.987	0.013	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.985	0.015	0.000
M80-M85 Disorders of bone density and structure	0.980	0.020	0.000
K70.3 Alcoholic cirrhosis of liver	0.979	0.021	0.000
K76.6 Portal hypertension	0.976	0.024	0.000
I20.9 Angina pectoris, unspecified	0.000	0.026	0.974
M20-M25 Other joint disorders	0.973	0.027	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.970	0.030	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.959	0.041	0.000
S80-S89 Injuries to the knee and lower leg	0.955	0.045	0.000
Chapter VIII Diseases of the ear and mastoid process	0.954	0.046	0.000
M81 Osteoporosis without pathological fracture	0.949	0.051	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.944	0.056	0.000
I25.1 Atherosclerotic heart disease	0.000	0.063	0.937
M81.9 Osteoporosis, unspecified	0.929	0.071	0.000
M23 Internal derangement of knee	0.929	0.071	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.081	0.919
K76.9 Liver disease, unspecified	0.911	0.089	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.910	0.090	0.000
W00-W19 Falls	0.907	0.093	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.903	0.097	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.903	0.097	0.000
Chapter VII Diseases of the eye and adnexa	0.900	0.100	0.000
M23.3 Other meniscus derangements	0.900	0.100	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.898	0.102	0.000
Chapter XXII Codes for special purposes	0.895	0.105	0.000
M25 Other joint disorders, not elsewhere classified	0.890	0.110	0.000
I20.0 Unstable angina	0.000	0.117	0.883
Chapter I Certain infectious and parasitic diseases	0.879	0.121	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.869	0.131	0.000
S82 Fracture of lower leg, including ankle	0.868	0.132	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.862	0.138	0.000
B25-B34 Other viral diseases	0.861	0.139	0.000
H60-H62 Diseases of external ear	0.861	0.139	0.000
K13 Other diseases of lip and oral mucosa	0.856	0.144	0.000
K70.9 Alcoholic liver disease, unspecified	0.850	0.150	0.000
S50-S59 Injuries to the elbow and forearm	0.849	0.151	0.000
T66-T78 Other and unspecified effects of external causes	0.847	0.153	0.000
K75 Other inflammatory liver diseases	0.847	0.153	0.000
W19 Unspecified fall	0.845	0.155	0.000
Y52 Agents primarily affecting the cardiovascular system	0.843	0.156	0.000
B34 Viral infection of unspecified site	0.844	0.156	0.000
I22 Subsequent myocardial infarction	0.000	0.157	0.843
M86-M90 Other osteopathies	0.842	0.158	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.841	0.159	0.000
K40-K46 Hernia	0.840	0.160	0.000
Chapter IX Diseases of the circulatory system	0.834	0.165	0.001
K72 Hepatic failure, not elsewhere classified	0.834	0.166	0.000
H43-H45 Disorders of vitreous body and globe	0.833	0.167	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.828	0.172	0.000
Y42.5 Other oestrogens and progestogens	0.827	0.173	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.823	0.177	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.822	0.178	0.000
M84 Disorders of continuity of bone	0.822	0.178	0.000
W20-W49 Exposure to inanimate mechanical forces	0.821	0.179	0.000
M05-M14 Inflammatory polyarthropathies	0.821	0.179	0.000
M35 Other systemic involvement of connective tissue	0.820	0.180	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.817	0.183	0.000
B34.9 Viral infection, unspecified	0.817	0.183	0.000
M81.98 Osteoporosis, unspecified (Other)	0.814	0.186	0.000
H90-H95 Other disorders of ear	0.814	0.186	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.810	0.190	0.000
S40-S49 Injuries to the shoulder and upper arm	0.810	0.190	0.000
M85 Other disorders of bone density and structure	0.808	0.191	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.806	0.194	0.000
I20.8 Other forms of angina pectoris	0.000	0.194	0.806
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.804	0.196	0.000
H61 Other disorders of external ear	0.802	0.198	0.000
K41 Femoral hernia	0.800	0.200	0.000
K70.4 Alcoholic hepatic failure	0.800	0.200	0.000
S82.6 Fracture of lateral malleolus	0.800	0.200	0.000
M22 Disorders of patella	0.800	0.200	0.000
M21 Other acquired deformities of limbs	0.796	0.204	0.000
M23.8 Other internal derangements of knee	0.795	0.205	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.795	0.205	0.000
H10-H13 Disorders of conjunctiva	0.792	0.208	0.000
S80 Superficial injury of lower leg	0.791	0.209	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.790	0.210	0.000
K11 Diseases of salivary glands	0.789	0.211	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.787	0.213	0.000
H43 Disorders of vitreous body	0.787	0.213	0.000
H80-H83 Diseases of inner ear	0.786	0.214	0.000
I30-I52 Other forms of heart disease	0.785	0.215	0.000
S86 Injury of muscle and tendon at lower leg level	0.785	0.215	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.785	0.215	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.784	0.216	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.783	0.217	0.000
M60-M63 Disorders of muscles	0.780	0.220	0.000
S10-S19 Injuries to the neck	0.780	0.220	0.000
M91-M94 Chondropathies	0.777	0.223	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.777	0.223	0.000
Y42.7 Androgens and anabolic congeners	0.777	0.223	0.000
Y40 Systemic antibiotics	0.775	0.225	0.000
S81 Open wound of lower leg	0.775	0.225	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.775	0.225	0.000
M00-M03 Infectious arthropathies	0.774	0.226	0.000
H61.0 Perichondritis of external ear	0.771	0.228	0.000
I25.5 Ischaemic cardiomyopathy	0.000	0.229	0.771
K74.0 Hepatic fibrosis	0.769	0.231	0.000
Chapter V Mental and behavioural disorders	0.768	0.232	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.767	0.233	0.000
Y44 Agents primarily affecting blood constituents	0.764	0.236	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.762	0.238	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.238	0.762
Q20-Q28 Congenital malformations of the circulatory system	0.761	0.239	0.000
Y57 Other and unspecified drugs and medicaments	0.759	0.241	0.000
M23.4 Loose body in knee	0.758	0.242	0.000
S82.8 Fractures of other parts of lower leg	0.757	0.243	0.000
I34 Nonrheumatic mitral valve disorders	0.756	0.244	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.756	0.244	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.755	0.244	0.000
Y00-Y09 Assault	0.755	0.245	0.000
M33 Dermatopolymyositis	0.755	0.245	0.000
M25.5 Pain in joint	0.754	0.246	0.000
M06 Other rheumatoid arthritis	0.753	0.247	0.000
S70-S79 Injuries to the hip and thigh	0.753	0.247	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.752	0.248	0.000
S82.60 Fracture of lateral malleolus (closed)	0.751	0.249	0.000
W19.9 Unspecified place	0.750	0.250	0.000
H30-H36 Disorders of choroid and retina	0.750	0.250	0.000
S90-S99 Injuries to the ankle and foot	0.749	0.251	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.749	0.251	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.255	0.745
M25.3 Other instability of joint	0.744	0.256	0.000
X20-X29 Contact with venomous animals and plants	0.743	0.257	0.000
M25.7 Osteophyte	0.742	0.258	0.000
V40-V49 Car occupant injured in transport accident	0.742	0.258	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.741	0.259	0.000
Chapter VI Diseases of the nervous system	0.738	0.262	0.000
I35 Nonrheumatic aortic valve disorders	0.738	0.262	0.000
K70.0 Alcoholic fatty liver	0.736	0.264	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.736	0.264	0.000
M82 Osteoporosis in diseases classified elsewhere	0.736	0.264	0.000
K10 Other diseases of jaws	0.736	0.264	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.735	0.264	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.735	0.265	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.734	0.266	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.732	0.268	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.732	0.268	0.000
T78 Adverse effects, not elsewhere classified	0.732	0.268	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.732	0.268	0.000
H90 Conductive and sensorineural hearing loss	0.731	0.269	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.729	0.271	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.729	0.271	0.000
T20 Burn and corrosion of head and neck	0.728	0.271	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.728	0.272	0.000
I34.1 Mitral (valve) prolapse	0.728	0.272	0.000
S52 Fracture of forearm	0.727	0.273	0.000
V20-V29 Motorcycle rider injured in transport accident	0.727	0.273	0.000
B15-B19 Viral hepatitis	0.725	0.275	0.000
H11 Other disorders of conjunctiva	0.724	0.276	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.723	0.277	0.000
M23.1 Discoid meniscus (congenital)	0.723	0.277	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.722	0.278	0.000
K00 Disorders of tooth development and eruption	0.720	0.280	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.280	0.720
V10-V19 Pedal cyclist injured in transport accident	0.718	0.282	0.000
H43.8 Other disorders of vitreous body	0.717	0.283	0.000
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I25.4 Coronary artery aneurysm	0.000	0.283	0.717
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.283	0.717
I23 Certain current complications following acute myocardial infarction	0.000	0.283	0.717
K77 Liver disorders in diseases classified elsewhere	0.717	0.283	0.000
K73 Chronic hepatitis, not elsewhere classified	0.717	0.283	0.000
K71 Toxic liver disease	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.283	0.717
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
T23 Burn and corrosion of wrist and hand	0.717	0.283	0.000
K76.7 Hepatorenal syndrome	0.717	0.283	0.000
K76.5 Hepatic veno-occlusive disease	0.717	0.283	0.000
K76.4 Peliosis hepatis	0.717	0.283	0.000
K76.3 Infarction of liver	0.717	0.283	0.000
K76.2 Central haemorrhagic necrosis of liver	0.717	0.283	0.000
K76.1 Chronic passive congestion of liver	0.717	0.283	0.000
T87 Complications peculiar to reattachment and amputation	0.716	0.284	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.716	0.284	0.000
T81.9 Unspecified complication of procedure	0.716	0.284	0.000
T81.7 Vascular complications following a procedure, not elsewhere classified	0.716	0.284	0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.716	0.284	0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.716	0.284	0.000
I33 Acute and subacute endocarditis	0.715	0.285	0.000
Y35-Y36 Legal intervention and operations of war	0.715	0.285	0.000
Y10-Y34 Event of undetermined intent	0.715	0.285	0.000
X85-X99 Assault	0.715	0.285	0.000
X50-X57 Overexertion, travel and privation	0.715	0.285	0.000
X30-X39 Exposure to forces of nature	0.715	0.285	0.000
X10-X19 Contact with heat and hot substances	0.715	0.285	0.000
X00-X09 Exposure to smoke, fire and flames	0.715	0.285	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.715	0.285	0.000
W75-W84 Other accidental threats to breathing	0.715	0.285	0.000
W65-W74 Accidental drowning and submersion	0.715	0.285	0.000
W50-W64 Exposure to animate mechanical forces	0.715	0.285	0.000
V98-V99 Other and unspecified transport accidents	0.715	0.285	0.000
V95-V97 Air and space transport accidents	0.715	0.285	0.000
V90-V94 Water transport accidents	0.715	0.285	0.000
V80-V89 Other land transport accidents	0.715	0.285	0.000
V70-V79 Bus occupant injured in transport accident	0.715	0.285	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.715	0.285	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.715	0.285	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.715	0.285	0.000
V01-V09 Pedestrian injured in transport accident	0.715	0.285	0.000
M25.9 Joint disorder, unspecified	0.713	0.287	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.713	0.287	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.711	0.288	0.000
K74.5 Biliary cirrhosis, unspecified	0.711	0.289	0.000
K74.4 Secondary biliary cirrhosis	0.711	0.289	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.711	0.289	0.000
K74.1 Hepatic sclerosis	0.711	0.289	0.000
Y59 Other and unspecified vaccines and biological substances	0.711	0.289	0.000
Y58 Bacterial vaccines	0.711	0.289	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.711	0.289	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.711	0.289	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.711	0.289	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.711	0.289	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.711	0.289	0.000
Y48 Anaesthetics and therapeutic gases	0.711	0.289	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.711	0.289	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.711	0.289	0.000
T86 Failure and rejection of transplanted organs and tissues	0.709	0.291	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.708	0.292	0.000
I42 Cardiomyopathy	0.707	0.293	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.706	0.294	0.000
M84.0 Malunion of fracture	0.705	0.295	0.000
S81.8 Open wound of other parts of lower leg	0.705	0.295	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.705	0.295	0.000
M83 Adult osteomalacia	0.703	0.297	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.702	0.298	0.000
M80 Osteoporosis with pathological fracture	0.702	0.298	0.000
B34.4 Papovirus infection, unspecified	0.701	0.299	0.000
K75.8 Other specified inflammatory liver diseases	0.701	0.299	0.000
W29 Contact with other powered hand tools and household machinery	0.699	0.301	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.699	0.301	0.000
B50-B64 Protozoal diseases	0.698	0.302	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.698	0.302	0.000
M34 Systemic sclerosis	0.698	0.302	0.000
M32 Systemic lupus erythematosus	0.698	0.302	0.000
M30 Polyarteritis nodosa and related conditions	0.698	0.302	0.000
K05 Gingivitis and periodontal diseases	0.697	0.303	0.000
W07 Fall involving chair	0.695	0.305	0.000
B35-B49 Mycoses	0.694	0.306	0.000
M22.3 Other derangements of patella	0.694	0.306	0.000
H43.3 Other vitreous opacities	0.694	0.306	0.000
K12 Stomatitis and related lesions	0.693	0.307	0.000
X60-X84 Intentional self-harm	0.692	0.308	0.000
I72 Other aneurysm	0.692	0.308	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.691	0.309	0.000
I71 Aortic aneurysm and dissection	0.691	0.309	0.000
I25.3 Aneurysm of heart	0.000	0.310	0.690
B27 Infectious mononucleosis	0.689	0.310	0.000
T79-T79 Certain early complications of trauma	0.688	0.311	0.000
W19.1 Residential institution	0.688	0.312	0.000
K76.8 Other specified diseases of liver	0.688	0.312	0.000
W19.3 Sports and athletics area	0.687	0.313	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.686	0.314	0.000
M85.8 Other specified disorders of bone density and structure	0.686	0.314	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.685	0.315	0.000
S88 Traumatic amputation of lower leg	0.685	0.315	0.000
S87 Crushing injury of lower leg	0.685	0.315	0.000
S85 Injury of blood vessels at lower leg level	0.685	0.315	0.000
S84 Injury of nerves at lower leg level	0.685	0.315	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.682	0.318	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.682	0.318	0.000
I35.1 Aortic (valve) insufficiency	0.681	0.319	0.000
M81.8 Other osteoporosis	0.680	0.320	0.000
M81.6 Localised osteoporosis [Lequesne]	0.680	0.320	0.000
M81.5 Idiopathic osteoporosis	0.680	0.320	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.680	0.320	0.000
M81.2 Osteoporosis of disuse	0.680	0.320	0.000
M81.1 Postoophorectomy osteoporosis	0.680	0.320	0.000
M81.0 Postmenopausal osteoporosis	0.680	0.320	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.680	0.320	0.000
M87 Osteonecrosis	0.679	0.320	0.000
H35 Other retinal disorders	0.679	0.321	0.000
K07 Dentofacial anomalies [including malocclusion]	0.678	0.322	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.678	0.322	0.000
Y42.9 Other and unspecified hormone antagonists	0.677	0.323	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.677	0.323	0.000
Y42.4 Oral contraceptives	0.677	0.323	0.000
Y42.2 Antithyroid drugs	0.677	0.323	0.000
Y42.1 Thyroid hormones and substitutes	0.677	0.323	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.677	0.323	0.000
K72.0 Acute and subacute hepatic failure	0.677	0.323	0.000
T82.1 Mechanical complication of cardiac electronic device	0.677	0.323	0.000
Y45.2 Propionic acid derivatives	0.677	0.323	0.000
H83 Other diseases of inner ear	0.674	0.326	0.000
Y45.0 Opioids and related analgesics	0.674	0.326	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.673	0.327	0.000
I31 Other diseases of pericardium	0.673	0.327	0.000
M06.0 Seronegative rheumatoid arthritis	0.671	0.329	0.000
W08 Fall involving other furniture	0.670	0.330	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.668	0.332	0.000
F60-F69 Disorders of adult personality and behaviour	0.667	0.333	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.666	0.334	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.666	0.334	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.666	0.334	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.666	0.334	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.666	0.334	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.666	0.334	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.666	0.334	0.000
M23.9 Internal derangement of knee, unspecified	0.666	0.334	0.000
M23.0 Cystic meniscus	0.666	0.334	0.000
U89 Agent resistant to other and unspecified antibiotics	0.666	0.334	0.000
I33.0 Acute and subacute infective endocarditis	0.666	0.334	0.000
S42 Fracture of shoulder and upper arm	0.665	0.335	0.000
W18 Other fall on same level	0.664	0.336	0.000
K09 Cysts of oral region, not elsewhere classified	0.663	0.337	0.000
M25.0 Haemarthrosis	0.663	0.337	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.663	0.337	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.663	0.337	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.661	0.338	0.000
S59 Other and unspecified injuries of forearm	0.660	0.339	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.660	0.340	0.000
T18 Foreign body in alimentary tract	0.660	0.340	0.000
Q80-Q89 Other congenital malformations	0.659	0.341	0.000
S51 Open wound of forearm	0.659	0.341	0.000
M84.4 Pathological fracture, not elsewhere classified	0.658	0.341	0.000
H65-H75 Diseases of middle ear and mastoid	0.658	0.342	0.000
K75.0 Abscess of liver	0.657	0.342	0.000
M21.6 Other acquired deformities of ankle and foot	0.657	0.343	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.656	0.344	0.000
K72.9 Hepatic failure, unspecified	0.656	0.344	0.000
M35.3 Polymyalgia rheumatica	0.653	0.347	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.653	0.347	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.653	0.347	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.347	0.652
W19.2 School, other institution and public administrative area	0.653	0.347	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.651	0.348	0.000
W17 Other fall from one level to another	0.650	0.349	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.650	0.349	0.000
W15 Fall from cliff	0.650	0.349	0.000
W14 Fall from tree	0.650	0.349	0.000
W12 Fall on and from scaffolding	0.650	0.349	0.000
W11 Fall on and from ladder	0.650	0.349	0.000
W09 Fall involving playground equipment	0.650	0.349	0.000
W05 Fall involving wheelchair	0.650	0.349	0.000
W04 Fall while being carried or supported by other persons	0.650	0.349	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.650	0.349	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.650	0.349	0.000
W00 Fall on same level involving ice and snow	0.650	0.349	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.650	0.350	0.000
K75.4 Autoimmune hepatitis	0.650	0.350	0.000
K11.5 Sialolithiasis	0.650	0.350	0.000
B34.8 Other viral infections of unspecified site	0.650	0.350	0.000
Y60.0 During surgical operation	0.649	0.351	0.000
K45 Other abdominal hernia	0.649	0.351	0.000
M25.54 Pain in joint (Hand)	0.648	0.352	0.000
K03 Other diseases of hard tissues of teeth	0.648	0.352	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.647	0.352	0.000
T25 Burn and corrosion of ankle and foot	0.647	0.353	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.647	0.353	0.000
T21 Burn and corrosion of trunk	0.647	0.353	0.000
M23.37 Other meniscus derangements-Capsular lig	0.645	0.355	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.645	0.355	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.645	0.355	0.000
S80.8 Other superficial injuries of lower leg	0.644	0.356	0.000
M86 Osteomyelitis	0.644	0.356	0.000
M06.4 Inflammatory polyarthropathy	0.643	0.357	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.642	0.358	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.641	0.359	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.641	0.359	0.000
M88 Paget's disease of bone [osteitis deformans]	0.641	0.359	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.640	0.360	0.000
M90 Osteopathies in diseases classified elsewhere	0.640	0.360	0.000
M25.37 Other instability of joint (Ankle and foot)	0.639	0.361	0.000
M25.2 Flail joint	0.638	0.362	0.000
M25.1 Fistula of joint	0.638	0.362	0.000
M35.1 Other overlap syndromes	0.637	0.363	0.000
M81.4 Drug-induced osteoporosis	0.636	0.363	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.636	0.364	0.000
W06 Fall involving bed	0.636	0.364	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.635	0.364	0.000
Q50-Q56 Congenital malformations of genital organs	0.635	0.365	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.635	0.365	0.000
M23.49 Loose body in knee-Unspec lig/men	0.635	0.365	0.000
K70.1 Alcoholic hepatitis	0.634	0.365	0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.634	0.366	0.000
Q23 Congenital malformations of aortic and mitral valves	0.634	0.366	0.000
Q24 Other congenital malformations of heart	0.634	0.366	0.000
D68 Other coagulation defects	0.633	0.367	0.000
U88 Agent resistant to multiple antibiotics	0.631	0.369	0.000
B99-B99 Other infectious diseases	0.630	0.370	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.630	0.370	0.000
B65-B83 Helminthiases	0.630	0.370	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.630	0.370	0.000
A75-A79 Rickettsioses	0.630	0.370	0.000
A70-A74 Other diseases caused by chlamydiae	0.630	0.370	0.000
A65-A69 Other spirochaetal diseases	0.630	0.370	0.000
A20-A28 Certain zoonotic bacterial diseases	0.630	0.370	0.000
A15-A19 Tuberculosis	0.630	0.370	0.000
Y44.5 Thrombolytic drugs	0.629	0.371	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.629	0.371	0.000
W25 Contact with sharp glass	0.628	0.372	0.000
I38 Endocarditis, valve unspecified	0.628	0.372	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.627	0.373	0.000
M62 Other disorders of muscle	0.627	0.373	0.000
M35.0 Sicca syndrome [Sjogren]	0.626	0.374	0.000
K11.2 Sialoadenitis	0.625	0.375	0.000
H35.9 Retinal disorder, unspecified	0.624	0.376	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.624	0.376	0.000
M05 Seropositive rheumatoid arthritis	0.623	0.377	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.623	0.377	0.000
Y45.8 Other analgesics and antipyretics	0.623	0.377	0.000
Y45.5 4-Aminophenol derivatives	0.623	0.377	0.000
Y45.4 Antirheumatics	0.623	0.377	0.000
Y45.1 Salicylates	0.623	0.377	0.000
S82.9 Fracture of lower leg, part unspecified	0.623	0.377	0.000
S82.7 Multiple fractures of lower leg	0.623	0.377	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.623	0.377	0.000
S10 Superficial injury of neck	0.622	0.378	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.622	0.378	0.000
S20-S29 Injuries to the thorax	0.621	0.379	0.000
S41 Open wound of shoulder and upper arm	0.620	0.379	0.000
G62 Other polyneuropathies	0.620	0.380	0.000
K08 Other disorders of teeth and supporting structures	0.620	0.380	0.000
M40-M43 Deforming dorsopathies	0.620	0.380	0.000
W10 Fall on and from stairs and steps	0.620	0.380	0.000
M25.51 Pain in joint (Shoulder region)	0.619	0.381	0.000
S80.9 Superficial injury of lower leg, unspecified	0.619	0.381	0.000
G61 Inflammatory polyneuropathy	0.619	0.381	0.000
T68 Hypothermia	0.619	0.381	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.618	0.382	0.000
Q35-Q37 Cleft lip and cleft palate	0.618	0.382	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.618	0.382	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.618	0.382	0.000
B33 Other viral diseases, not elsewhere classified	0.618	0.382	0.000
B30 Viral conjunctivitis	0.618	0.382	0.000
B26 Mumps	0.618	0.382	0.000
B25 Cytomegaloviral disease	0.618	0.382	0.000
H11.9 Disorder of conjunctiva, unspecified	0.617	0.383	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.617	0.383	0.000
I35.9 Aortic valve disorder, unspecified	0.617	0.383	0.000
M00 Pyogenic arthritis	0.617	0.383	0.000
M25.71 Osteophyte (Shoulder region)	0.616	0.384	0.000
S82.5 Fracture of medial malleolus	0.615	0.385	0.000
X59 Exposure to unspecified factor	0.615	0.385	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.615	0.385	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.614	0.386	0.000
K13.5 Oral submucous fibrosis	0.614	0.386	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.614	0.386	0.000
K13.3 Hairy leukoplakia	0.614	0.386	0.000
K13.1 Cheek and lip biting	0.614	0.386	0.000
H81 Disorders of vestibular function	0.612	0.388	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.612	0.388	0.000
W29.9 Unspecified place	0.612	0.388	0.000
M21.1 Varus deformity, not elsewhere classified	0.612	0.388	0.000
S89 Other and unspecified injuries of lower leg	0.612	0.388	0.000
S70 Superficial injury of hip and thigh	0.611	0.388	0.000
S52.5 Fracture of lower end of radius	0.611	0.389	0.000
I71.0 Dissection of aorta [any part]	0.611	0.389	0.000
S58 Traumatic amputation of forearm	0.609	0.391	0.000
S57 Crushing injury of forearm	0.609	0.391	0.000
S56 Injury of muscle and tendon at forearm level	0.609	0.391	0.000
S55 Injury of blood vessels at forearm level	0.609	0.391	0.000
S54 Injury of nerves at forearm level	0.609	0.391	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.609	0.391	0.000
B18 Chronic viral hepatitis	0.608	0.392	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.608	0.392	0.000
S82.2 Fracture of shaft of tibia	0.608	0.392	0.000
T75 Effects of other external causes	0.607	0.393	0.000
T74 Maltreatment syndromes	0.607	0.393	0.000
T73 Effects of other deprivation	0.607	0.393	0.000
T70 Effects of air pressure and water pressure	0.607	0.393	0.000
T69 Other effects of reduced temperature	0.607	0.393	0.000
T67 Effects of heat and light	0.607	0.393	0.000
T71 Asphyxiation	0.607	0.393	0.000
T66 Unspecified effects of radiation	0.607	0.393	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.607	0.393	0.000
K75.2 Nonspecific reactive hepatitis	0.607	0.393	0.000
K75.1 Phlebitis of portal vein	0.607	0.393	0.000
U80 Agent resistant to penicillin and related antibiotics	0.607	0.393	0.000
H52 Disorders of refraction and accommodation	0.607	0.393	0.000
S60-S69 Injuries to the wrist and hand	0.607	0.393	0.000
H55-H59 Other disorders of eye and adnexa	0.607	0.393	0.000
W19.8 Other specified place	0.606	0.394	0.000
W19.5 Trade and service area	0.606	0.394	0.000
W19.0 Home	0.606	0.394	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations