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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs964184
log Bayes Factor = 28.4991
Chromosome 11   position 116,648,917  (GRCh37) Explore rs964184 on Ensembl!
Variant rs964184 is listed in the   GWAS Catalog   ⇪
Variant rs964184 is part of Cluster X0104

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
1.000 0.000 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.999 0.001 0.000
E78.5 Hyperlipidaemia, unspecified
0.992 0.008 0.000
E78.2 Mixed hyperlipidaemia
0.988 0.012 0.000
I10 Essential (primary) hypertension
0.918 0.082 0.000
E78.4 Other hyperlipidaemia
0.873 0.127 0.000
E78.1 Pure hyperglyceridaemia
0.794 0.206 0.000
E78.3 Hyperchylomicronaemia
0.716 0.283 0.000
E78.6 Lipoprotein deficiency
0.700 0.300 0.000
E78.8 Other disorders of lipoprotein metabolism
0.689 0.311 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.684 0.316 0.000
I10-I15 Hypertensive diseases
0.331 0.669 0.000
I11 Hypertensive heart disease
0.263 0.737 0.000
I13 Hypertensive heart and renal disease
0.237 0.762 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.229 0.771 0.000
I15 Secondary hypertension
0.200 0.799 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.191 0.809 0.000
I71 Aortic aneurysm and dissection
0.188 0.812 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.184 0.816 0.000
I70 Atherosclerosis
0.173 0.827 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.170 0.829 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.170 0.829 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.170 0.829 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.170 0.829 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.169 0.831 0.000
I72 Other aneurysm
0.168 0.832 0.000
I74 Arterial embolism and thrombosis
0.168 0.832 0.000
I25 Chronic ischaemic heart disease
0.166 0.834 0.000
Chapter IX Diseases of the circulatory system
0.165 0.835 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.164 0.836 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.158 0.841 0.000
I20-I25 Ischaemic heart diseases
0.156 0.844 0.000
I72.4 Aneurysm of artery of lower extremity
0.155 0.845 0.000
I70.0 Atherosclerosis of aorta
0.154 0.846 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.153 0.847 0.000
I15.9 Seconday hypertension, unspecified
0.150 0.849 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.149 0.851 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.147 0.853 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.146 0.854 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.146 0.854 0.000
I15.8 Other secondary hypertension
0.144 0.856 0.000
I15.2 Hypertension secondary to endocrine disorders
0.144 0.856 0.000
I15.0 Renovascular hypertension
0.144 0.856 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.143 0.857 0.000
I25.1 Atherosclerotic heart disease
0.142 0.858 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.140 0.860 0.000
I70.8 Atherosclerosis of other arteries
0.138 0.862 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.135 0.865 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.135 0.865 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.135 0.865 0.000
I72.0 Aneurysm of carotid artery
0.131 0.869 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.128 0.872 0.000
I70.9 Generalised and unspecified atherosclerosis
0.124 0.876 0.000
I74.5 Embolism and thrombosis of iliac artery
0.124 0.876 0.000
I74.8 Embolism and thrombosis of other arteries
0.123 0.877 0.000
I70.1 Atherosclerosis of renal artery
0.121 0.879 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.120 0.879 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.120 0.879 0.000
I72.2 Aneurysm of renal artery
0.120 0.879 0.000
I72.1 Aneurysm of artery of upper extremity
0.120 0.879 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.120 0.879 0.000
I72.3 Aneurysm of iliac artery
0.120 0.879 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.120 0.880 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.119 0.880 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.119 0.881 0.000
I25.6 Silent myocardial ischaemia
0.119 0.881 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.119 0.881 0.000
I25.4 Coronary artery aneurysm
0.119 0.881 0.000
I00-I02 Acute rheumatic fever
0.118 0.882 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.118 0.882 0.000
I24 Other acute ischaemic heart diseases
0.117 0.883 0.000
I72.9 Aneurysm of unspecified site
0.116 0.884 0.000
I72.8 Aneurysm of other specified arteries
0.115 0.885 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.115 0.885 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.113 0.887 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.112 0.887 0.000
I70.01 Atherosclerosis of aorta (with gangrene)
0.110 0.889 0.000
I77 Other disorders of arteries and arterioles
0.110 0.890 0.000
I23 Certain current complications following acute myocardial infarction
0.107 0.893 0.000
I25.3 Aneurysm of heart
0.104 0.896 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.100 0.900 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.099 0.901 0.000
I12 Hypertensive renal disease
0.097 0.903 0.000
I15.1 Hypertension secondary to other renal disorders
0.094 0.906 0.001
I25.5 Ischaemic cardiomyopathy
0.092 0.908 0.000
I77.1 Stricture of artery
0.092 0.908 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.089 0.911 0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.089 0.911 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.087 0.913 0.000
I20 Angina pectoris
0.087 0.913 0.000
I78 Diseases of capillaries
0.086 0.914 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.086 0.914 0.000
I79.1 Aortitis in diseases classified elsewhere
0.086 0.914 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.086 0.914 0.000
I02 Rheumatic chorea
0.085 0.915 0.000
I01 Rheumatic fever with heart involvement
0.085 0.915 0.000
I00 Rheumatic fever without mention of heart involvement
0.085 0.915 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.083 0.916 0.000
I24.1 Dressler's syndrome
0.083 0.917 0.000
I05-I09 Chronic rheumatic heart diseases
0.083 0.917 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.082 0.918 0.000
I77.5 Necrosis of artery
0.079 0.921 0.000
I77.4 Coeliac artery compression syndrome
0.079 0.921 0.000
I77.3 Arterial fibromuscular dysplasia
0.079 0.921 0.000
I77.2 Rupture of artery
0.079 0.921 0.000
I71.0 Dissection of aorta [any part]
0.077 0.923 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.077 0.923 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.077 0.923 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.077 0.923 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.077 0.923 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.077 0.923 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.077 0.923 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.077 0.923 0.000
I73 Other peripheral vascular diseases
0.077 0.923 0.000
I20.9 Angina pectoris, unspecified
0.077 0.923 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.072 0.927 0.000
I77.0 Arteriovenous fistula, acquired
0.072 0.927 0.000
I23.8 Other current complications following acute myocardial infarction
0.072 0.927 0.000
I77.8 Other specified disorders of arteries and arterioles
0.071 0.929 0.000
I07 Rheumatic tricuspid valve diseases
0.067 0.933 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.066 0.934 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.065 0.935 0.000
I25.2 Old myocardial infarction
0.064 0.936 0.000
I78.9 Disease of capillaries, unspecified
0.062 0.938 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.061 0.939 0.000
I01.8 Other acute rheumatic heart disease
0.061 0.939 0.000
I01.2 Acute rheumatic myocarditis
0.061 0.939 0.000
I01.1 Acute rheumatic endocarditis
0.061 0.939 0.000
I01.0 Acute rheumatic pericarditis
0.061 0.939 0.000
I02.9 Rheumatic chorea without heart involvement
0.061 0.939 0.000
I02.0 Rheumatic chorea with heart involvement
0.061 0.939 0.000
I06 Rheumatic aortic valve diseases
0.059 0.941 0.000
I78.8 Other diseases of capillaries
0.059 0.941 0.000
I05 Rheumatic mitral valve diseases
0.057 0.943 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.055 0.944 0.000
I20.1 Angina pectoris with documented spasm
0.055 0.945 0.000
I07.1 Tricuspid insufficiency
0.055 0.945 0.000
I73.8 Other specified peripheral vascular diseases
0.054 0.945 0.000
I99 Other and unspecified disorders of circulatory system
0.054 0.946 0.000
I09 Other rheumatic heart diseases
0.054 0.946 0.000
Z95.1 Presence of aortocoronary bypass graft
0.049 0.951 0.000
I07.9 Tricuspid valve disease, unspecified
0.048 0.952 0.000
I07.8 Other tricuspid valve diseases
0.048 0.952 0.000
I07.2 Tricuspid stenosis with insufficiency
0.048 0.952 0.000
I07.0 Tricuspid stenosis
0.048 0.952 0.000
I05.0 Mitral stenosis
0.048 0.952 0.000
I77.6 Arteritis, unspecified
0.047 0.953 0.000
I05.2 Mitral stenosis with insufficiency
0.047 0.953 0.000
I12.9 Hypertensive renal disease without renal failure
0.046 0.954 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.043 0.957 0.000
I06.8 Other rheumatic aortic valve diseases
0.043 0.957 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.043 0.957 0.000
I06.1 Rheumatic aortic insufficiency
0.043 0.957 0.000
I06.0 Rheumatic aortic stenosis
0.043 0.957 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.042 0.957 0.000
I20.8 Other forms of angina pectoris
0.042 0.958 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.041 0.958 0.000
I05.8 Other mitral valve diseases
0.041 0.959 0.000
I73.9 Peripheral vascular disease, unspecified
0.041 0.959 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.040 0.960 0.000
I09.8 Other specified rheumatic heart diseases
0.039 0.961 0.000
I09.2 Chronic rheumatic pericarditis
0.039 0.961 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.039 0.961 0.000
I09.0 Rheumatic myocarditis
0.039 0.961 0.000
I21 Acute myocardial infarction
0.038 0.962 0.000
I22 Subsequent myocardial infarction
0.036 0.963 0.001
I20.0 Unstable angina
0.037 0.963 0.000
I05.1 Rheumatic mitral insufficiency
0.036 0.964 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.035 0.965 0.000
I24.8 Other forms of acute ischaemic heart disease
0.034 0.966 0.000
I09.9 Rheumatic heart disease, unspecified
0.033 0.966 0.000
I73.0 Raynaud's syndrome
0.033 0.967 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.031 0.969 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.030 0.970 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.029 0.971 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.029 0.971 0.000
I98.0 Cardiovascular syphilis
0.029 0.971 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.029 0.971 0.000
I28 Other diseases of pulmonary vessels
0.028 0.972 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.027 0.972 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.027 0.973 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.026 0.973 0.001
I97.9 Postprocedural disorder of circulatory system, unspecified
0.025 0.975 0.000
I97.0 Postcardiotomy syndrome
0.025 0.975 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.024 0.976 0.000
I97.1 Other functional disturbances following cardiac surgery
0.023 0.977 0.000
I21.4 Acute subendocardial myocardial infarction
0.022 0.978 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.021 0.979 0.000
I08 Multiple valve diseases
0.021 0.979 0.000
I22.8 Subsequent myocardial infarction of other sites
0.020 0.980 0.001
I28.9 Disease of pulmonary vessels, unspecified
0.020 0.980 0.000
I28.1 Aneurysm of pulmonary artery
0.020 0.980 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.020 0.980 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.020 0.980 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.019 0.980 0.001
I05.9 Mitral valve disease, unspecified
0.017 0.982 0.001
I08.9 Multiple valve disease, unspecified
0.018 0.982 0.000
D75 Other diseases of blood and blood-forming organs
0.000 0.982 0.018
I28.8 Other specified diseases of pulmonary vessels
0.017 0.983 0.000
I26 Pulmonary embolism
0.017 0.983 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.983 0.017
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.983 0.017
D75.1 Secondary polycythaemia
0.000 0.983 0.017
D75.2 Essential thrombocytosis
0.000 0.984 0.016
R26.8 Other and unspecified abnormalities of gait and mobility
0.016 0.984 0.000
E70-E90 Metabolic disorders
0.015 0.985 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.014 0.986 0.000
I08.8 Other multiple valve diseases
0.013 0.987 0.000
D75.0 Familial erythrocytosis
0.000 0.987 0.012
I08.0 Disorders of both mitral and aortic valves
0.012 0.988 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.012 0.988 0.000
E80.6 Other disorders of bilirubin metabolism
0.012 0.988 0.000
I78.1 Naevus, nonneoplastic
0.011 0.988 0.001
E80.1 Porphyria cutanea tarda
0.011 0.989 0.000
E80.4 Gilbert's syndrome
0.011 0.989 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.011 0.989 0.000
E84 Cystic fibrosis
0.011 0.989 0.000
E79 Disorders of purine and pyrimidine metabolism
0.011 0.989 0.000
E77 Disorders of glycoprotein metabolism
0.011 0.989 0.000
E76 Disorders of glycosaminoglycan metabolism
0.011 0.989 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.011 0.989 0.000
E72 Other disorders of amino-acid metabolism
0.011 0.989 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.011 0.989 0.000
E70 Disorders of aromatic amino-acid metabolism
0.011 0.989 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.011 0.989 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.010 0.989 0.000
E74 Other disorders of carbohydrate metabolism
0.010 0.990 0.000
E85 Amyloidosis
0.010 0.990 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.010 0.990 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.010 0.990 0.000
E80.5 Crigler-Najjar syndrome
0.010 0.990 0.000
E80.3 Defects of catalase and peroxydase
0.010 0.990 0.000
E80.2 Other porphyria
0.010 0.990 0.000
E80.0 Hereditary erythropoietic porphyria
0.010 0.990 0.000
I27 Other pulmonary heart diseases
0.010 0.990 0.000
G43.9 Migraine, unspecified
0.000 0.990 0.010
R26 Abnormalities of gait and mobility
0.010 0.990 0.000
E88 Other metabolic disorders
0.009 0.991 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.009 0.991 0.000
E73 Lactose intolerance
0.009 0.991 0.000
I95 Hypotension
0.008 0.991 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.008 0.992 0.000
E85.9 Amyloidosis, unspecified
0.008 0.992 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.008 0.992 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.008 0.992 0.000
E70.3 Albinism
0.008 0.992 0.000
E70.2 Disorders of tyrosine metabolism
0.008 0.992 0.000
E70.1 Other hyperphenylalaninaemias
0.008 0.992 0.000
E70.0 Classical phenylketonuria
0.008 0.992 0.000
E71.3 Disorders of fatty-acid metabolism
0.008 0.992 0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.008 0.992 0.000
E71.1 Other disorders of branched-chain amino-acid metabolism
0.008 0.992 0.000
E71.0 Maple-syrup-urine disease
0.008 0.992 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.008 0.992 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.008 0.992 0.000
E72.5 Disorders of glycine metabolism
0.008 0.992 0.000
E72.4 Disorders of ornithine metabolism
0.008 0.992 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.008 0.992 0.000
E72.2 Disorders of urea cycle metabolism
0.008 0.992 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.008 0.992 0.000
E72.0 Disorders of amino-acid transport
0.008 0.992 0.000
E75.6 Lipid storage disorder, unspecified
0.008 0.992 0.000
E75.5 Other lipid storage disorders
0.008 0.992 0.000
E75.4 Neuronal ceroid lipofuscinosis
0.008 0.992 0.000
E75.3 Sphingolipidosis, unspecified
0.008 0.992 0.000
E75.2 Other sphingolipidosis
0.008 0.992 0.000
E75.1 Other gangliosidosis
0.008 0.992 0.000
E75.0 GM2 gangliosidosis
0.008 0.992 0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.008 0.992 0.000
E76.8 Other disorders of glucosaminoglycan metabolism
0.008 0.992 0.000
E76.3 Mucopolysaccharidosis, unspecified
0.008 0.992 0.000
E76.2 Other mucopolysaccharidoses
0.008 0.992 0.000
E76.1 Mucopolysaccharidosis, type II
0.008 0.992 0.000
E76.0 Mucopolysaccharidosis, type I
0.008 0.992 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.008 0.992 0.000
E77.8 Other disorders of glycoprotein metabolism
0.008 0.992 0.000
E77.1 Defects in glycoprotein degradation
0.008 0.992 0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.008 0.992 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.008 0.992 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.008 0.992 0.000
E79.1 Lesch-Nyhan syndrome
0.008 0.992 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.008 0.992 0.000
E84.9 Cystic fibrosis, unspecified
0.008 0.992 0.000
E84.8 Cystic fibrosis with other manifestations
0.008 0.992 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.008 0.992 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.008 0.992 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.008 0.992 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.008 0.992 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.008 0.992 0.000
E74.2 Disorders of galactose metabolism
0.008 0.992 0.000
E74.1 Disorders of fructose metabolism
0.008 0.992 0.000
E74.0 Glycogen storage disease
0.008 0.992 0.000
E85.8 Other amyloidosis
0.008 0.992 0.000
E85.3 Secondary systemic amyloidosis
0.008 0.992 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.008 0.992 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.008 0.992 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.008 0.992 0.000
I12.0 Hypertensive renal disease with renal failure
0.007 0.992 0.000
I95.8 Other hypotension
0.007 0.992 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.007 0.993 0.000
E88.8 Other specified metabolic disorders
0.007 0.993 0.000
I27.1 Kyphoscoliotic heart disease
0.007 0.993 0.000
R26.1 Paralytic gait
0.007 0.993 0.000
I60-I69 Cerebrovascular diseases
0.007 0.993 0.000
E88.2 Lipomatosis, not elsewhere classified
0.007 0.993 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.005 0.993 0.002
E85.4 Organ-limited amyloidosis
0.007 0.993 0.000
E88.9 Metabolic disorder, unspecified
0.007 0.993 0.000
E88.3 Tumour lysis syndrome
0.007 0.993 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.007 0.993 0.000
R26.0 Ataxic gait
0.007 0.993 0.000
E73.8 Other lactose intolerance
0.006 0.993 0.000
E73.1 Secondary lactase deficiency
0.006 0.993 0.000
E73.0 Congenital lactase deficiency
0.006 0.993 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.007 0.993 0.000
R26.3 Immobility
0.006 0.993 0.000
I65.2 Occlusion and stenosis of carotid artery
0.006 0.994 0.000
I95.0 Idiopathic hypotension
0.006 0.994 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.006 0.994 0.000
Q61.3 Polycystic kidney, unspecified
0.000 0.994 0.006
I64 Stroke, not specified as haemorrhage or infarction
0.006 0.994 0.000
I27.8 Other specified pulmonary heart diseases
0.005 0.994 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.000 0.994 0.006
Q61.2 Polycystic kidney, adult type
0.000 0.994 0.006
I27.0 Primary pulmonary hypertension
0.005 0.994 0.000
S92 Fracture of foot, except ankle
0.006 0.994 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.005 0.995 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.005 0.995 0.000
I27.2 Other secondary pulmonary hypertension
0.005 0.995 0.000
Q61 Cystic kidney disease
0.000 0.995 0.005
S92.2 Fracture of other tarsal bone(s)
0.005 0.995 0.000
S92.0 Fracture of calcaneus
0.005 0.995 0.000
S92.3 Fracture of metatarsal bone
0.005 0.995 0.000
S92.00 Fracture of calcaneus (closed)
0.005 0.995 0.000
S92.20 Fracture of other tarsal bone(s) (closed)
0.005 0.995 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.005 0.995 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.005 0.995 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.005 0.995 0.000
I65.1 Occlusion and stenosis of basilar artery
0.005 0.995 0.000
S92.30 Fracture of metatarsal bone (closed)
0.005 0.995 0.000
E73.9 Lactose intolerance, unspecified
0.005 0.995 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.005 0.995 0.000
G43 Migraine
0.000 0.995 0.005
M81.90 Osteoporosis, unspecified (Multiple sites)
0.005 0.995 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.004 0.995 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.004 0.995 0.000
E89.5 Postprocedural testicular hypofunction
0.004 0.995 0.000
E89.4 Postprocedural ovarian failure
0.004 0.995 0.000
E89.1 Postprocedural hypoinsulinaemia
0.004 0.995 0.000
E89.2 Postprocedural hypoparathyroidism
0.004 0.995 0.000
S92.4 Fracture of great toe
0.004 0.995 0.000
I27.9 Pulmonary heart disease, unspecified
0.004 0.996 0.001
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.004 0.996 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.004 0.996 0.000
S92.5 Fracture of other toe
0.004 0.996 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.004 0.996 0.000
E89.3 Postprocedural hypopituitarism
0.004 0.996 0.000
S92.9 Fracture of foot, unspecified
0.004 0.996 0.000
S92.1 Fracture of talus
0.004 0.996 0.000
Q61.5 Medullary cystic kidney
0.000 0.996 0.004
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.004 0.996 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.004 0.996 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.004 0.996 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.004 0.996 0.000
I66.2 Occlusion and stenosis of posterior cerebral artery
0.004 0.996 0.000
I66.1 Occlusion and stenosis of anterior cerebral artery
0.004 0.996 0.000
I66.0 Occlusion and stenosis of middle cerebral artery
0.004 0.996 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.004 0.996 0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.004 0.996 0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.004 0.996 0.000
I68.0 Cerebral amyloid angiopathy
0.004 0.996 0.000
E28.2 Polycystic ovarian syndrome
0.004 0.996 0.000
Q61.0 Congenital single renal cyst
0.000 0.996 0.004
R25.2 Cramp and spasm
0.004 0.996 0.000
R25 Abnormal involuntary movements
0.004 0.996 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.000 0.996 0.004
Q61.8 Other cystic kidney diseases
0.000 0.996 0.004
Q61.4 Renal dysplasia
0.000 0.996 0.004
Q61.1 Polycystic kidney, infantile type
0.000 0.996 0.004
S90-S99 Injuries to the ankle and foot
0.004 0.996 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.996 0.004
S92.01 Fracture of calcaneus (open)
0.004 0.996 0.000
S92.21 Fracture of other tarsal bone(s) (open)
0.004 0.996 0.000
S92.7 Multiple fractures of foot
0.004 0.996 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.004 0.996 0.000
S92.31 Fracture of metatarsal bone (open)
0.004 0.996 0.000
G43.1 Migraine with aura [classical migraine]
0.000 0.996 0.004
M81.99 Osteoporosis, unspecified (Site unspecified)
0.004 0.996 0.000
S92.40 Fracture of great toe (closed)
0.004 0.996 0.000
K90.0 Coeliac disease
0.004 0.996 0.000
I61 Intracerebral haemorrhage
0.004 0.996 0.000
G43.8 Other migraine
0.000 0.996 0.004
Q61.9 Cystic kidney disease, unspecified
0.000 0.996 0.004
G43.3 Complicated migraine
0.000 0.996 0.004
G43.2 Status migrainosus
0.000 0.996 0.004
M81.9 Osteoporosis, unspecified
0.004 0.996 0.000
E28 Ovarian dysfunction
0.004 0.996 0.000
G43.0 Migraine without aura [common migraine]
0.000 0.996 0.004
S93.0 Dislocation of ankle joint
0.004 0.996 0.000
Z95.4 Presence of other heart-valve replacement
0.004 0.996 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.004 0.996 0.000
D18.0 Haemangioma, any site
0.000 0.996 0.004
R25.1 Tremor, unspecified
0.004 0.996 0.000
I67 Other cerebrovascular diseases
0.004 0.996 0.000
D73 Diseases of spleen
0.000 0.996 0.003
H61.0 Perichondritis of external ear
0.003 0.996 0.000
E23 Hypofunction and other disorders of pituitary gland
0.003 0.996 0.000
S92.50 Fracture of other toe (closed)
0.003 0.997 0.000
S93.1 Dislocation of toe(s)
0.003 0.997 0.000
S99 Other and unspecified injuries of ankle and foot
0.003 0.997 0.000
S92.41 Fracture of great toe (open)
0.003 0.997 0.000
S92.51 Fracture of other toe (open)
0.003 0.997 0.000
R25.3 Fasciculation
0.003 0.997 0.000
I62 Other nontraumatic intracranial haemorrhage
0.003 0.997 0.001
E20-E35 Disorders of other endocrine glands
0.003 0.997 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.003 0.997 0.000
I61.8 Other intracerebral haemorrhage
0.003 0.997 0.000
S92.11 Fracture of talus (open)
0.003 0.997 0.000
S92.91 Fracture of foot, unspecified (open)
0.003 0.997 0.000
S92.90 Fracture of foot, unspecified (closed)
0.003 0.997 0.000
S93.3 Dislocation of other and unspecified parts of foot
0.003 0.997 0.000
S92.10 Fracture of talus (closed)
0.003 0.997 0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.000 0.997 0.003
E23.7 Disorder of pituitary gland, unspecified
0.003 0.997 0.000
R25.0 Abnormal head movements
0.003 0.997 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.000 0.997 0.003
I61.3 Intracerebral haemorrhage in brain stem
0.003 0.997 0.000
D74 Methaemoglobinaemia
0.000 0.997 0.003
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.997 0.003
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.997 0.003
S98 Traumatic amputation of ankle and foot
0.003 0.997 0.000
S97 Crushing injury of ankle and foot
0.003 0.997 0.000
S95 Injury of blood vessels at ankle and foot level
0.003 0.997 0.000
S94 Injury of nerves at ankle and foot level
0.003 0.997 0.000
G93.8 Other specified disorders of brain
0.003 0.997 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.003 0.997 0.000
S92.71 Multiple fractures of foot (open)
0.003 0.997 0.000
M35.0 Sicca syndrome [Sjogren]
0.003 0.997 0.000
S93.4 Sprain and strain of ankle
0.003 0.997 0.000
S93.6 Sprain and strain of other and unspecified parts of foot
0.003 0.997 0.000
S93.5 Sprain and strain of toe(s)
0.003 0.997 0.000
S93.2 Rupture of ligaments at ankle and foot level
0.003 0.997 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.997 0.003
E23.2 Diabetes insipidus
0.003 0.997 0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level
0.003 0.997 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.003 0.997 0.000
Q89.2 Congenital malformations of other endocrine glands
0.003 0.997 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.003 0.997 0.000
E22 Hyperfunction of pituitary gland
0.003 0.997 0.000
S96.8 Injury of other muscles and tendons at ankle and foot level
0.003 0.997 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.003 0.997 0.000
M70.22 Olecranon bursitis-Upper arm
0.000 0.997 0.003
D73.0 Hyposplenism
0.000 0.997 0.003
I61.6 Intracerebral haemorrhage, multiple localised
0.003 0.997 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.003 0.997 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.003 0.997 0.000
Z45.8 Adjustment and management of other implanted devices
0.003 0.997 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.003 0.997 0.000
S90 Superficial injury of ankle and foot
0.003 0.997 0.000
S99.9 Unspecified injury of ankle and foot
0.003 0.997 0.000
J69.0 Pneumonitis due to food and vomit
0.000 0.997 0.003
E23.0 Hypopituitarism
0.003 0.997 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.003 0.997 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.003 0.997 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.003 0.997 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.003 0.997 0.000
E22.0 Acromegaly and pituitary gigantism
0.003 0.997 0.000
E28.9 Ovarian dysfunction, unspecified
0.003 0.997 0.000
E28.8 Other ovarian dysfunction
0.003 0.997 0.000
E28.1 Androgen excess
0.003 0.997 0.000
E28.0 Oestrogen excess
0.003 0.997 0.000
S92.70 Multiple fractures of foot (closed)
0.003 0.997 0.000
E28.3 Primary ovarian failure
0.003 0.997 0.000
E21.0 Primary hyperparathyroidism
0.003 0.997 0.000
I95.2 Hypotension due to drugs
0.002 0.997 0.001
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.003 0.997 0.000
D73.5 Infarction of spleen
0.000 0.997 0.003
S91 Open wound of ankle and foot
0.003 0.997 0.000
K60.1 Chronic anal fissure
0.000 0.997 0.003
S96.9 Injury of unspecified muscle and tendon at ankle and foot level
0.003 0.997 0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level
0.003 0.997 0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level
0.003 0.997 0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level
0.003 0.997 0.000
R27 Other lack of coordination
0.003 0.997 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.003 0.997 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.003 0.997 0.000
I67.5 Moyamoya disease
0.003 0.997 0.000
I67.4 Hypertensive encephalopathy
0.003 0.997 0.000
I67.3 Progressive vascular leukoencephalopathy
0.003 0.997 0.000
D73.9 Disease of spleen, unspecified
0.000 0.997 0.003
D73.8 Other diseases of spleen
0.000 0.997 0.003
D73.4 Cyst of spleen
0.000 0.997 0.003
D73.3 Abscess of spleen
0.000 0.997 0.003
D73.2 Chronic congestive splenomegaly
0.000 0.997 0.003
D73.1 Hypersplenism
0.000 0.997 0.003
I61.5 Intracerebral haemorrhage, intraventricular
0.003 0.997 0.000
I82.8 Embolism and thrombosis of other specified veins
0.003 0.997 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.003 0.997 0.000
E23.1 Drug-induced hypopituitarism
0.003 0.997 0.000
D72 Other disorders of white blood cells
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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