TreeWAS – Variant ID: rs9646096

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M79.66 Pain in limb (Lower leg)	0.000	0.985	0.015
Z03.5 Observation for other suspected cardiovascular diseases	0.014	0.986	0.000
Z03.8 Observation for other suspected diseases and conditions	0.012	0.988	0.000
Z03 Medical observation and evaluation for suspected diseases and conditions	0.011	0.989	0.000
Z03.9 Observation for suspected disease or condition, unspecified	0.009	0.991	0.000
Z03.2 Observation for suspected mental and behavioural disorders	0.009	0.991	0.000
Z03.6 Observation for suspected toxic effect from ingested substance	0.008	0.992	0.000
H66 Suppurative and unspecified otitis media	0.008	0.992	0.000
Z03.3 Observation for suspected nervous system disorder	0.008	0.992	0.000
H66.9 Otitis media, unspecified	0.008	0.992	0.000
Z03.0 Observation for suspected tuberculosis	0.008	0.992	0.000
H66.3 Other chronic suppurative otitis media	0.008	0.992	0.000
J39.2 Other diseases of pharynx	0.007	0.992	0.000
H65-H75 Diseases of middle ear and mastoid	0.007	0.993	0.000
D12.6 Colon, unspecified	0.000	0.994	0.006
Chapter VIII Diseases of the ear and mastoid process	0.006	0.994	0.000
H73 Other disorders of tympanic membrane	0.006	0.994	0.000
H65 Nonsuppurative otitis media	0.006	0.994	0.000
H66.4 Suppurative otitis media, unspecified	0.006	0.994	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.006	0.994	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.006	0.994	0.000
H66.0 Acute suppurative otitis media	0.006	0.994	0.000
H80-H83 Diseases of inner ear	0.006	0.994	0.000
H60-H62 Diseases of external ear	0.006	0.994	0.000
H61 Other disorders of external ear	0.006	0.994	0.000
H61.2 Impacted cerumen	0.006	0.994	0.000
H69 Other disorders of Eustachian tube	0.006	0.994	0.000
R00.2 Palpitations	0.006	0.994	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.005	0.994	0.000
H70 Mastoiditis and related conditions	0.005	0.994	0.000
H68 Eustachian salpingitis and obstruction	0.005	0.994	0.000
H67 Otitis media in diseases classified elsewhere	0.005	0.994	0.000
H83 Other diseases of inner ear	0.005	0.995	0.000
H81 Disorders of vestibular function	0.005	0.995	0.000
H74 Other disorders of middle ear and mastoid	0.005	0.995	0.000
H73.8 Other specified disorders of tympanic membrane	0.005	0.995	0.000
H90-H95 Other disorders of ear	0.005	0.995	0.000
S00.8 Superficial injury of other parts of head	0.005	0.995	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.005	0.995	0.000
H72 Perforation of tympanic membrane	0.005	0.995	0.000
H61.1 Non-infective disorders of pinna	0.005	0.995	0.000
Z03.1 Observation for suspected malignant neoplasm	0.005	0.995	0.000
H61.3 Acquired stenosis of external ear canal	0.005	0.995	0.000
H83.0 Labyrinthitis	0.005	0.995	0.000
H81.1 Benign paroxysmal vertigo	0.005	0.995	0.000
H65.3 Chronic mucoid otitis media	0.005	0.995	0.000
H65.2 Chronic serous otitis media	0.005	0.995	0.000
H65.1 Other acute nonsuppurative otitis media	0.005	0.995	0.000
H65.0 Acute serous otitis media	0.005	0.995	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.005	0.995	0.000
H73.1 Chronic myringitis	0.005	0.995	0.000
H73.0 Acute myringitis	0.005	0.995	0.000
S00 Superficial injury of head	0.005	0.995	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.004	0.995	0.000
H92 Otalgia and effusion of ear	0.005	0.995	0.000
S09.9 Unspecified injury of head	0.005	0.995	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.004	0.995	0.000
H90 Conductive and sensorineural hearing loss	0.005	0.995	0.000
S00.9 Superficial injury of head, part unspecified	0.005	0.995	0.000
H65.4 Other chronic nonsuppurative otitis media	0.004	0.995	0.000
H61.9 Disorder of external ear, unspecified	0.004	0.996	0.000
H92.1 Otorrhoea	0.004	0.996	0.000
H80 Otosclerosis	0.004	0.996	0.000
H71 Cholesteatoma of middle ear	0.004	0.996	0.000
H69.9 Eustachian tube disorder, unspecified	0.004	0.996	0.000
H81.2 Vestibular neuronitis	0.004	0.996	0.000
H69.8 Other specified disorders of Eustachian tube	0.004	0.996	0.000
H69.0 Patulous Eustachian tube	0.004	0.996	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.004	0.996	0.000
H60 Otitis externa	0.004	0.996	0.000
H74.0 Tympanosclerosis	0.004	0.996	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.004	0.996	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.004	0.996	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.004	0.996	0.000
H68.1 Obstruction of Eustachian tube	0.004	0.996	0.000
H68.0 Eustachian salpingitis	0.004	0.996	0.000
H70.9 Mastoiditis, unspecified	0.004	0.996	0.000
H70.8 Other mastoiditis and related conditions	0.004	0.996	0.000
H70.2 Petrositis	0.004	0.996	0.000
H70.1 Chronic mastoiditis	0.004	0.996	0.000
H70.0 Acute mastoiditis	0.004	0.996	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.004	0.996	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
H81.9 Disorder of vestibular function, unspecified	0.004	0.996	0.000
H81.8 Other disorders of vestibular function	0.004	0.996	0.000
H81.4 Vertigo of central origin	0.004	0.996	0.000
H81.3 Other peripheral vertigo	0.004	0.996	0.000
H83.9 Disease of inner ear, unspecified	0.004	0.996	0.000
H83.8 Other specified diseases of inner ear	0.004	0.996	0.000
H83.3 Noise effects on inner ear	0.004	0.996	0.000
H83.2 Labyrinthine dysfunction	0.004	0.996	0.000
H83.1 Labyrinthine fistula	0.004	0.996	0.000
H61.8 Other specified disorders of external ear	0.004	0.996	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.004	0.996	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.004	0.996	0.000
H74.1 Adhesive middle ear disease	0.004	0.996	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.000	0.996	0.004
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.004	0.996	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.004	0.996	0.000
H74.4 Polyp of middle ear	0.004	0.996	0.000
H72.8 Other perforations of tympanic membrane	0.004	0.996	0.000
H81.0 Meniere's disease	0.004	0.996	0.000
S09 Other and unspecified injuries of head	0.004	0.996	0.000
H72.2 Other marginal perforations of tympanic membrane	0.004	0.996	0.000
H72.1 Attic perforation of tympanic membrane	0.004	0.996	0.000
S00.5 Superficial injury of lip and oral cavity	0.004	0.996	0.000
H90.3 Sensorineural hearing loss, bilateral	0.004	0.996	0.000
M79.6 Pain in limb	0.000	0.996	0.004
H72.9 Perforation of tympanic membrane, unspecified	0.004	0.996	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.004	0.996	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.004	0.996	0.000
H91 Other hearing loss	0.004	0.996	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.004	0.996	0.000
H93 Other disorders of ear, not elsewhere classified	0.004	0.996	0.000
H60.5 Acute otitis externa, non-infective	0.004	0.996	0.000
S00-S09 Injuries to the head	0.004	0.996	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.004	0.996	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
S00.3 Superficial injury of nose	0.004	0.996	0.000
H90.2 Conductive hearing loss, unspecified	0.004	0.996	0.000
S00.4 Superficial injury of ear	0.004	0.996	0.000
H72.0 Central perforation of tympanic membrane	0.003	0.996	0.000
H92.2 Otorrhagia	0.003	0.996	0.000
S00.0 Superficial injury of scalp	0.003	0.996	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.003	0.996	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.003	0.996	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.003	0.996	0.000
H62.2 Otitis externa in mycoses	0.003	0.996	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.003	0.996	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.003	0.996	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.996	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.003	0.996	0.000
H90.0 Conductive hearing loss, bilateral	0.003	0.996	0.000
H80.8 Other otosclerosis	0.003	0.997	0.000
H80.2 Cochlear otosclerosis	0.003	0.997	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.003	0.997	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.003	0.997	0.000
S00.7 Multiple superficial injuries of head	0.003	0.997	0.000
H91.3 Deaf mutism, not elsewhere classified	0.003	0.997	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.003	0.997	0.000
H60.8 Other otitis externa	0.003	0.997	0.000
H60.4 Cholesteatoma of external ear	0.003	0.997	0.000
H60.3 Other infective otitis externa	0.003	0.997	0.000
H60.2 Malignant otitis externa	0.003	0.997	0.000
H60.0 Abscess of external ear	0.003	0.997	0.000
H61.0 Perichondritis of external ear	0.003	0.997	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.003	0.997	0.000
Z03.4 Observation for suspected myocardial infarction	0.003	0.997	0.000
J39 Other diseases of upper respiratory tract	0.003	0.997	0.000
S01 Open wound of head	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.003	0.997	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.003	0.997	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.003	0.997	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.003	0.997	0.000
H95.1 Other disorders following mastoidectomy	0.003	0.997	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.003	0.997	0.000
H80.9 Otosclerosis, unspecified	0.003	0.997	0.000
S01.2 Open wound of nose	0.003	0.997	0.000
S09.7 Multiple injuries of head	0.003	0.997	0.000
S09.2 Traumatic rupture of ear drum	0.003	0.997	0.000
S09.1 Injury of muscle and tendon of head	0.003	0.997	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.003	0.997	0.000
H91.8 Other specified hearing loss	0.003	0.997	0.000
K91.4 Colostomy and enterostomy malfunction	0.003	0.997	0.000
S09.8 Other specified injuries of head	0.003	0.997	0.000
M79.68 Pain in limb (Other)	0.000	0.997	0.003
H60.1 Cellulitis of external ear	0.003	0.997	0.000
M79.61 Pain in limb (Shoulder region)	0.000	0.997	0.003
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
H92.0 Otalgia	0.003	0.997	0.000
H91.2 Sudden idiopathic hearing loss	0.003	0.997	0.000
H91.1 Presbycusis	0.003	0.997	0.000
H91.0 Ototoxic hearing loss	0.003	0.997	0.000
K91.3 Postoperative intestinal obstruction	0.003	0.997	0.000
M79.63 Pain in limb (Forearm)	0.000	0.997	0.003
K90.0 Coeliac disease	0.003	0.997	0.000
S06 Intracranial injury	0.003	0.997	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.997	0.003
J39.9 Disease of upper respiratory tract, unspecified	0.003	0.997	0.000
H93.9 Disorder of ear, unspecified	0.003	0.997	0.000
H93.8 Other specified disorders of ear	0.003	0.997	0.000
H93.3 Disorders of acoustic nerve	0.003	0.997	0.000
H93.2 Other abnormal auditory perceptions	0.003	0.997	0.000
H93.0 Degenerative and vascular disorders of ear	0.003	0.997	0.000
S08 Traumatic amputation of part of head	0.003	0.997	0.000
S07 Crushing injury of head	0.003	0.997	0.000
S05 Injury of eye and orbit	0.003	0.997	0.000
S04 Injury of cranial nerves	0.003	0.997	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.003	0.997	0.000
R12 Heartburn	0.000	0.997	0.003
S01.5 Open wound of lip and oral cavity	0.003	0.997	0.000
S01.4 Open wound of cheek and temporomandibular area	0.003	0.997	0.000
K90 Intestinal malabsorption	0.003	0.997	0.000
M79.62 Pain in limb (Upper arm)	0.000	0.997	0.003
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.003	0.997	0.000
S06.8 Other intracranial injuries	0.003	0.997	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.997	0.003
N50.8 Other specified disorders of male genital organs	0.003	0.997	0.000
M79.64 Pain in limb (Hand)	0.000	0.997	0.003
S06.80 Other intracranial injuries (without open intracranial wound)	0.003	0.997	0.000
S01.7 Multiple open wounds of head	0.003	0.997	0.000
H60.9 Otitis externa, unspecified	0.003	0.997	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.997	0.003
M79.60 Pain in limb (Multiple sites)	0.000	0.997	0.003
K90.9 Intestinal malabsorption, unspecified	0.003	0.997	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.003	0.997	0.000
K91.5 Postcholecystectomy syndrome	0.003	0.997	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.003	0.997	0.000
K91.1 Postgastric surgery syndromes	0.003	0.997	0.000
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.003	0.997	0.000
J39.1 Other abscess of pharynx	0.003	0.997	0.000
J39.0 Retropharyngeal and parapharyngeal abscess	0.003	0.997	0.000
S01.9 Open wound of head, part unspecified	0.003	0.997	0.000
S01.8 Open wound of other parts of head	0.003	0.997	0.000
H93.1 Tinnitus	0.002	0.997	0.000
S01.3 Open wound of ear	0.002	0.997	0.000
K90-K93 Other diseases of the digestive system	0.003	0.997	0.000
S01.1 Open wound of eyelid and periocular area	0.002	0.997	0.000
S06.0 Concussion	0.002	0.997	0.000
R14 Flatulence and related conditions	0.000	0.997	0.003
S00.1 Contusion of eyelid and periocular area	0.002	0.997	0.000
M79.69 Pain in limb (Site unspecified)	0.000	0.998	0.002
S06.9 Intracranial injury, unspecified	0.002	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.002	0.998	0.000
S06.3 Focal brain injury	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.002	0.998	0.000
O63.1 Prolonged second stage (of labour)	0.000	0.998	0.002
Z33 Pregnant state, incidental	0.002	0.998	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.002	0.998	0.000
S03.4 Sprain and strain of jaw	0.002	0.998	0.000
S03.3 Dislocation of other and unspecified parts of head	0.002	0.998	0.000
S03.2 Dislocation of tooth	0.002	0.998	0.000
S03.1 Dislocation of septal cartilage of nose	0.002	0.998	0.000
S03.0 Dislocation of jaw	0.002	0.998	0.000
S04.9 Injury of unspecified cranial nerve	0.002	0.998	0.000
S04.8 Injury of other cranial nerves	0.002	0.998	0.000
S04.7 Injury of accessory nerve	0.002	0.998	0.000
S04.6 Injury of acoustic nerve	0.002	0.998	0.000
S04.5 Injury of facial nerve	0.002	0.998	0.000
S04.4 Injury of abducent nerve	0.002	0.998	0.000
S04.3 Injury of trigeminal nerve	0.002	0.998	0.000
S04.2 Injury of trochlear nerve	0.002	0.998	0.000
S04.1 Injury of oculomotor nerve	0.002	0.998	0.000
S04.0 Injury of optic nerve and pathways	0.002	0.998	0.000
S05.9 Injury of eye and orbit, part unspecified	0.002	0.998	0.000
S05.8 Other injuries of eye and orbit	0.002	0.998	0.000
S05.7 Avulsion of eye	0.002	0.998	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.002	0.998	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.002	0.998	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.002	0.998	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.002	0.998	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.002	0.998	0.000
S05.1 Contusion of eyeball and orbital tissues	0.002	0.998	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.002	0.998	0.000
S07.9 Crushing injury of head, part unspecified	0.002	0.998	0.000
S07.8 Crushing injury of other parts of head	0.002	0.998	0.000
S07.1 Crushing injury of skull	0.002	0.998	0.000
S07.0 Crushing injury of face	0.002	0.998	0.000
S08.9 Traumatic amputation of unspecified part of head	0.002	0.998	0.000
S08.8 Traumatic amputation of other parts of head	0.002	0.998	0.000
S08.1 Traumatic amputation of ear	0.002	0.998	0.000
S08.0 Avulsion of scalp	0.002	0.998	0.000
K90.8 Other intestinal malabsorption	0.002	0.998	0.000
K90.3 Pancreatic steatorrhoea	0.002	0.998	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.002	0.998	0.000
K90.1 Tropical sprue	0.002	0.998	0.000
S06.5 Traumatic subdural haemorrhage	0.002	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.002	0.998	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.002	0.998	0.000
R18 Ascites	0.000	0.998	0.002
J39.8 Other specified diseases of upper respiratory tract	0.002	0.998	0.000
N50.1 Vascular disorders of male genital organs	0.002	0.998	0.000
N18.0 End-stage renal disease	0.000	0.998	0.002
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.998	0.002
S06.6 Traumatic subarachnoid haemorrhage	0.002	0.998	0.000
S06.00 Concussion (without open intracranial wound)	0.002	0.998	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.998	0.002
I84.5 External haemorrhoids without complication	0.002	0.998	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.998	0.002
K93 Disorders of other digestive organs in diseases classified elsewhere	0.002	0.998	0.000
N18 Chronic renal failure	0.000	0.998	0.002
S06.01 Concussion (with open intracranial wound)	0.002	0.998	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.002	0.998	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.002	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.002	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.002	0.998	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.002	0.998	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.002	0.998	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.002	0.998	0.000
N50 Other disorders of male genital organs	0.002	0.998	0.000
K92 Other diseases of digestive system	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.002	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
K92.9 Disease of digestive system, unspecified	0.002	0.998	0.000
Z35.5 Supervision of elderly primigravida	0.002	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.002	0.998	0.000
H91.9 Hearing loss, unspecified	0.002	0.998	0.000
Z85.5 Personal history of malignant neoplasm of urinary tract	0.000	0.998	0.002
R00.0 Tachycardia, unspecified	0.000	0.998	0.002
O20.0 Threatened abortion	0.002	0.998	0.000
K92.0 Haematemesis	0.002	0.998	0.000
Z35 Supervision of high-risk pregnancy	0.002	0.998	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
I65.2 Occlusion and stenosis of carotid artery	0.002	0.998	0.000
Z37.0 Single live birth	0.000	0.998	0.002
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.002	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.002	0.998	0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.000	0.998	0.002
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.002	0.998	0.000
K93.1 Megacolon in Chagas' disease	0.002	0.998	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.002	0.998	0.000
N18.8 Other chronic renal failure	0.000	0.998	0.002
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.002	0.998	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.000	0.998	0.002
M79.67 Pain in limb (Ankle and foot)	0.000	0.998	0.001
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.998	0.002
N18.5 Chronic kidney disease, stage 5	0.000	0.998	0.002
J44 Other chronic obstructive pulmonary disease	0.000	0.998	0.002
N19 Unspecified renal failure	0.000	0.998	0.002
Z35.0 Supervision of pregnancy with history of infertility	0.002	0.998	0.000
K92.8 Other specified diseases of digestive system	0.002	0.998	0.000
N50.9 Disorder of male genital organs, unspecified	0.002	0.998	0.000
L82 Seborrhoeic keratosis	0.000	0.998	0.002
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.002	0.998	0.000
S02 Fracture of skull and facial bones	0.002	0.998	0.000
Z35.8 Supervision of other high-risk pregnancies	0.001	0.998	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.001	0.998	0.000
Z35.6 Supervision of very young primigravida	0.001	0.998	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.001	0.998	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.001	0.998	0.000
Z39.0 Care and examination immediately after delivery	0.002	0.998	0.000
R17 Unspecified jaundice	0.000	0.998	0.002
E53.8 Deficiency of other specified B group vitamins	0.002	0.998	0.000
N18.2 Chronic kidney disease, stage 2	0.000	0.998	0.001
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
N50.0 Atrophy of testis	0.001	0.998	0.000
T20.1 Burn of first degree of head and neck	0.001	0.998	0.000
R11 Nausea and vomiting	0.000	0.998	0.002
Z39 Postpartum care and examination	0.002	0.998	0.000
S42.40 Fracture of lower end of humerus (closed)	0.001	0.998	0.000
B34.9 Viral infection, unspecified	0.002	0.998	0.000
J38.2 Nodules of vocal cords	0.002	0.998	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.002	0.998	0.000
Z34.0 Supervision of normal first pregnancy	0.001	0.998	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.001	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.001	0.998	0.000
N18.1 Chronic kidney disease, stage 1	0.000	0.998	0.001
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.998	0.002
N17-N19 Renal failure	0.000	0.998	0.002
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.001	0.998	0.000
N43.3 Hydrocele, unspecified	0.000	0.998	0.001
S12.1 Fracture of second cervical vertebra	0.001	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.001	0.998	0.000
I12 Hypertensive renal disease	0.000	0.998	0.001
S12 Fracture of neck	0.001	0.998	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.002	0.998	0.000
K92.2 Gastro-intestinal haemorrhage, unspecified	0.002	0.998	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.001	0.998	0.000
T20 Burn and corrosion of head and neck	0.001	0.998	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.001	0.998	0.000
H33.3 Retinal breaks without detachment	0.000	0.998	0.002
S64.3 Injury of digital nerve of thumb	0.001	0.998	0.000
S83.7 Injury to multiple structures of knee	0.001	0.998	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.001	0.998	0.000
S83.3 Tear of articular cartilage of knee, current	0.001	0.998	0.000
S83.1 Dislocation of knee	0.001	0.998	0.000
S83.0 Dislocation of patella	0.001	0.998	0.000
Z37 Outcome of delivery	0.000	0.998	0.001
M62.80 Other specified disorders of muscle (Multiple sites)	0.001	0.999	0.000
S42.30 Fracture of shaft of humerus (closed)	0.001	0.999	0.000
S12.2 Fracture of other specified cervical vertebra	0.001	0.999	0.000
T17.2 Foreign body in pharynx	0.001	0.999	0.000
Z48.9 Surgical follow-up care, unspecified	0.000	0.999	0.001
S02.9 Fracture of skull and facial bones, part unspecified	0.001	0.999	0.000
S02.7 Multiple fractures involving skull and facial bones	0.001	0.999	0.000
Z29.1 Prophylactic immunotherapy	0.001	0.999	0.000
T23 Burn and corrosion of wrist and hand	0.001	0.999	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.001	0.999	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.001	0.999	0.000
G91.2 Normal-pressure hydrocephalus	0.001	0.999	0.000
S12.9 Fracture of neck, part unspecified	0.001	0.999	0.000
O20.8 Other haemorrhage in early pregnancy	0.001	0.999	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.999	0.001
Z30.3 Menstrual extraction	0.001	0.999	0.000
Z39.2 Routine postpartum follow-up	0.001	0.999	0.000
R15 Faecal incontinence	0.000	0.999	0.001
Q43.0 Meckel's diverticulum	0.001	0.999	0.000
S02.0 Fracture of vault of skull	0.001	0.999	0.000
T23.2 Burn of second degree of wrist and hand	0.001	0.999	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.001	0.999	0.000
Z48.8 Other specified surgical follow-up care	0.000	0.999	0.001
Z48.0 Attention to surgical dressings and sutures	0.000	0.999	0.001
S81 Open wound of lower leg	0.001	0.999	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.001	0.999	0.000
S81.0 Open wound of knee	0.001	0.999	0.000
T23.3 Burn of third degree of wrist and hand	0.001	0.999	0.000
G91 Hydrocephalus	0.001	0.999	0.000
N17 Acute renal failure	0.000	0.999	0.001
T17 Foreign body in respiratory tract	0.001	0.999	0.000
S80-S89 Injuries to the knee and lower leg	0.001	0.999	0.000
K63.9 Disease of intestine, unspecified	0.000	0.999	0.001
S02.8 Fractures of other skull and facial bones	0.001	0.999	0.000
S81.9 Open wound of lower leg, part unspecified	0.001	0.999	0.000
S83.2 Tear of meniscus, current	0.001	0.999	0.000
Z37.2 Twins, both liveborn	0.000	0.999	0.001
S86 Injury of muscle and tendon at lower leg level	0.001	0.999	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.999	0.001
M62.88 Other specified disorders of muscle (Other)	0.001	0.999	0.000
S12.11 Fracture of second cervical vertebra (open)	0.001	0.999	0.000
O26.9 Pregnancy-related condition, unspecified	0.001	0.999	0.000
S02.4 Fracture of malar and maxillary bones	0.001	0.999	0.000
S12.8 Fracture of other parts of neck	0.001	0.999	0.000
S12.7 Multiple fractures of cervical spine	0.001	0.999	0.000
S12.0 Fracture of first cervical vertebra	0.001	0.999	0.000
S42.4 Fracture of lower end of humerus	0.001	0.999	0.000
Z38 Liveborn infants according to place of birth	0.001	0.999	0.000
G91.1 Obstructive hydrocephalus	0.001	0.999	0.000
N60.0 Solitary cyst of breast	0.000	0.999	0.001
R16.1 Splenomegaly, not elsewhere classified	0.000	0.999	0.001
S02.5 Fracture of tooth	0.001	0.999	0.000
S02.3 Fracture of orbital floor	0.001	0.999	0.000
S02.1 Fracture of base of skull	0.001	0.999	0.000
T20.7 Corrosion of third degree of head and neck	0.001	0.999	0.000
T20.6 Corrosion of second degree of head and neck	0.001	0.999	0.000
T20.5 Corrosion of first degree of head and neck	0.001	0.999	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.001	0.999	0.000
T20.3 Burn of third degree of head and neck	0.001	0.999	0.000
T20.2 Burn of second degree of head and neck	0.001	0.999	0.000
T20.0 Burn of unspecified degree of head and neck	0.001	0.999	0.000
Z39.1 Care and examination of lactating mother	0.001	0.999	0.000
Z30 Contraceptive management	0.001	0.999	0.000
S10-S19 Injuries to the neck	0.001	0.999	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.001	0.999	0.000
S01.0 Open wound of scalp	0.001	0.999	0.000
S42.3 Fracture of shaft of humerus	0.001	0.999	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.001	0.999	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.001	0.999	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.001	0.999	0.000
Z37.9 Outcome of delivery unspecified	0.000	0.999	0.001
Z37.7 Other multiple births, all stillborn	0.000	0.999	0.001
Z37.6 Other multiple births, some liveborn	0.000	0.999	0.001
Z37.5 Other multiple births, all liveborn	0.000	0.999	0.001
Z37.4 Twins, both stillborn	0.000	0.999	0.001
Z37.3 Twins, one liveborn and one stillborn	0.000	0.999	0.001
Z37.1 Single stillbirth	0.000	0.999	0.001
O24 Diabetes mellitus in pregnancy	0.001	0.999	0.000
S64 Injury of nerves at wrist and hand level	0.001	0.999	0.000
Z31 Procreative management	0.001	0.999	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.001	0.999	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.001	0.999	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.001	0.999	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.001	0.999	0.000
S12.91 Fracture of neck, part unspecified (open)	0.001	0.999	0.000
S02.6 Fracture of mandible	0.001	0.999	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.001	0.999	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.001	0.999	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.001	0.999	0.000
T23.7 Corrosion of third degree of wrist and hand	0.001	0.999	0.000
T23.6 Corrosion of second degree of wrist and hand	0.001	0.999	0.000
T23.5 Corrosion of first degree of wrist and hand	0.001	0.999	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.001	0.999	0.000
T23.1 Burn of first degree of wrist and hand	0.001	0.999	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.001	0.999	0.000
Z29.2 Other prophylactic chemotherapy	0.001	0.999	0.000
S90 Superficial injury of ankle and foot	0.001	0.999	0.000
T25 Burn and corrosion of ankle and foot	0.001	0.999	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.001	0.999	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T21 Burn and corrosion of trunk	0.001	0.999	0.000
N17.9 Acute renal failure, unspecified	0.000	0.999	0.001
T79.3 Post-traumatic wound infection, not elsewhere classified	0.001	0.999	0.000
S02.01 Fracture of vault of skull (open)	0.001	0.999	0.000
M62.8 Other specified disorders of muscle	0.001	0.999	0.000
N17.8 Other acute renal failure	0.000	0.999	0.001
N17.2 Acute renal failure with medullary necrosis	0.000	0.999	0.001
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.999	0.001
S81.7 Multiple open wounds of lower leg	0.001	0.999	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.001	0.999	0.000
Z31.2 In vitro fertilisation	0.001	0.999	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.001	0.999	0.000
N40 Hyperplasia of prostate	0.001	0.999	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.001	0.999	0.000
Z34 Supervision of normal pregnancy	0.001	0.999	0.000
Z32 Pregnancy examination and test	0.001	0.999	0.000
S90-S99 Injuries to the ankle and foot	0.001	0.999	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.001	0.999	0.000
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
G91.8 Other hydrocephalus	0.001	0.999	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.001	0.999	0.000
G91.0 Communicating hydrocephalus	0.001	0.999	0.000
O46.9 Antepartum haemorrhage, unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations