TreeWAS – Variant ID: rs9895098

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E27 Other disorders of adrenal gland	0.228	0.772	0.000
E27.1 Primary adrenocortical insufficiency	0.216	0.784	0.000
E20-E35 Disorders of other endocrine glands	0.214	0.786	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.213	0.787	0.000
E23 Hypofunction and other disorders of pituitary gland	0.207	0.793	0.000
E27.2 Addisonian crisis	0.196	0.803	0.000
E23.0 Hypopituitarism	0.194	0.806	0.000
E27.9 Disorder of adrenal gland, unspecified	0.191	0.809	0.000
E27.8 Other specified disorders of adrenal gland	0.191	0.809	0.000
E23.6 Other disorders of pituitary gland	0.171	0.829	0.000
E26 Hyperaldosteronism	0.171	0.829	0.000
E28 Ovarian dysfunction	0.170	0.830	0.000
E24 Cushing's syndrome	0.168	0.832	0.000
E23.2 Diabetes insipidus	0.165	0.835	0.000
E27.5 Adrenomedullary hyperfunction	0.164	0.836	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.164	0.836	0.000
E27.0 Other adrenocortical overactivity	0.164	0.836	0.000
E34 Other endocrine disorders	0.158	0.842	0.000
E29 Testicular dysfunction	0.157	0.842	0.000
E20 Hypoparathyroidism	0.156	0.844	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.154	0.846	0.000
E32 Diseases of thymus	0.154	0.846	0.000
E31 Polyglandular dysfunction	0.154	0.846	0.000
E30 Disorders of puberty, not elsewhere classified	0.154	0.846	0.000
E25 Adrenogenital disorders	0.154	0.846	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.154	0.846	0.000
E22 Hyperfunction of pituitary gland	0.152	0.847	0.000
E23.7 Disorder of pituitary gland, unspecified	0.150	0.850	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.149	0.851	0.000
E23.1 Drug-induced hypopituitarism	0.149	0.851	0.000
E26.0 Primary hyperaldosteronism	0.140	0.860	0.000
E22.0 Acromegaly and pituitary gigantism	0.139	0.861	0.000
E28.2 Polycystic ovarian syndrome	0.135	0.865	0.000
E24.9 Cushing's syndrome, unspecified	0.134	0.866	0.000
E28.3 Primary ovarian failure	0.126	0.874	0.000
E26.9 Hyperaldosteronism, unspecified	0.123	0.877	0.000
E26.8 Other hyperaldosteronism	0.123	0.877	0.000
E26.1 Secondary hyperaldosteronism	0.123	0.877	0.000
E28.9 Ovarian dysfunction, unspecified	0.122	0.878	0.000
E28.8 Other ovarian dysfunction	0.122	0.878	0.000
E28.1 Androgen excess	0.122	0.878	0.000
E28.0 Oestrogen excess	0.122	0.878	0.000
E21.3 Hyperparathyroidism, unspecified	0.121	0.879	0.000
E24.8 Other Cushing's syndrome	0.120	0.880	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.120	0.880	0.000
E24.3 Ectopic ACTH syndrome	0.120	0.880	0.000
E24.2 Drug-induced Cushing's syndrome	0.120	0.880	0.000
E24.1 Nelson's syndrome	0.120	0.880	0.000
E24.0 Pituitary-dependent Cushing's disease	0.120	0.880	0.000
E34.9 Endocrine disorder, unspecified	0.117	0.883	0.000
E29.1 Testicular hypofunction	0.117	0.883	0.000
E34.0 Carcinoid syndrome	0.116	0.884	0.000
E20.9 Hypoparathyroidism, unspecified	0.114	0.886	0.000
E34.5 Androgen resistance syndrome	0.113	0.887	0.000
E34.4 Constitutional tall stature	0.113	0.887	0.000
E34.3 Short stature, not elsewhere classified	0.113	0.887	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.113	0.887	0.000
E34.1 Other hypersecretion of intestinal hormones	0.113	0.887	0.000
E29.9 Testicular dysfunction, unspecified	0.113	0.887	0.000
E29.8 Other testicular dysfunction	0.113	0.887	0.000
E29.0 Testicular hyperfunction	0.113	0.887	0.000
E20.8 Other hypoparathyroidism	0.112	0.888	0.000
E20.1 Pseudohypoparathyroidism	0.112	0.888	0.000
E20.0 Idiopathic hypoparathyroidism	0.112	0.888	0.000
E34.8 Other specified endocrine disorders	0.111	0.889	0.000
E25.9 Adrenogenital disorder, unspecified	0.110	0.889	0.000
E25.8 Other adrenogenital disorders	0.110	0.889	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.110	0.889	0.000
E30.9 Disorder of puberty, unspecified	0.110	0.889	0.000
E30.8 Other disorders of puberty	0.110	0.889	0.000
E30.1 Precocious puberty	0.110	0.889	0.000
E30.0 Delayed puberty	0.110	0.889	0.000
E31.9 Polyglandular dysfunction, unspecified	0.110	0.889	0.000
E31.8 Other polyglandular dysfunction	0.110	0.889	0.000
E31.1 Polyglandular hyperfunction	0.110	0.889	0.000
E31.0 Autoimmune polyglandular failure	0.110	0.889	0.000
E32.9 Disease of thymus, unspecified	0.110	0.889	0.000
E32.8 Other diseases of thymus	0.110	0.889	0.000
E32.1 Abscess of thymus	0.110	0.889	0.000
E32.0 Persistent hyperplasia of thymus	0.110	0.889	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.110	0.889	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.110	0.889	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.110	0.889	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.110	0.890	0.000
E21.4 Other specified disorders of parathyroid gland	0.110	0.890	0.000
E21.2 Other hyperparathyroidism	0.110	0.890	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.109	0.890	0.000
E22.8 Other hyperfunction of pituitary gland	0.109	0.890	0.000
E21.0 Primary hyperparathyroidism	0.109	0.891	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.098	0.902	0.000
E22.1 Hyperprolactinaemia	0.085	0.914	0.000
N60 Benign mammary dysplasia	0.000	0.929	0.071
N60-N64 Disorders of breast	0.000	0.929	0.071
N64 Other disorders of breast	0.000	0.930	0.070
N64.8 Other specified disorders of breast	0.000	0.930	0.070
N60.4 Mammary duct ectasia	0.000	0.931	0.069
N62 Hypertrophy of breast	0.000	0.935	0.065
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.064	0.936	0.000
N60.8 Other benign mammary dysplasias	0.000	0.937	0.063
N60.3 Fibrosclerosis of breast	0.000	0.940	0.060
N64.5 Other signs and symptoms in breast	0.000	0.941	0.059
N60.2 Fibroadenosis of breast	0.000	0.942	0.058
N63 Unspecified lump in breast	0.000	0.944	0.056
N64.1 Fat necrosis of breast	0.000	0.947	0.053
N60.9 Benign mammary dysplasia, unspecified	0.000	0.948	0.052
N61 Inflammatory disorders of breast	0.000	0.948	0.052
Y83.2 Surgical operation with anastomosis, bypass or graft	0.051	0.949	0.000
N64.3 Galactorrhoea not associated with childbirth	0.000	0.949	0.051
N64.2 Atrophy of breast	0.000	0.949	0.051
N64.0 Fissure and fistula of nipple	0.000	0.949	0.051
N64.4 Mastodynia	0.000	0.950	0.049
N64.9 Disorder of breast, unspecified	0.000	0.957	0.043
N60.1 Diffuse cystic mastopathy	0.000	0.959	0.041
N60.0 Solitary cyst of breast	0.000	0.967	0.033
Z80.3 Family history of malignant neoplasm of breast	0.000	0.991	0.009
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.991	0.009
D48.1 Connective and other soft tissue	0.008	0.992	0.000
M47.2 Other spondylosis with radiculopathy	0.000	0.992	0.008
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.007	0.993	0.000
D48.7 Other specified sites	0.007	0.993	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.993	0.007
E87.2 Acidosis	0.000	0.993	0.007
Z96.8 Presence of other specified functional implants	0.006	0.994	0.000
D48.6 Breast	0.006	0.994	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.006	0.994	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.000	0.994	0.006
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.000	0.994	0.006
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.000	0.994	0.006
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.000	0.994	0.006
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.000	0.994	0.006
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.000	0.994	0.006
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.000	0.994	0.006
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.000	0.994	0.006
D48.5 Skin	0.006	0.994	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.006	0.994	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.005	0.994	0.000
D48.4 Peritoneum	0.005	0.994	0.000
D48.3 Retroperitoneum	0.005	0.994	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.005	0.994	0.000
D48.0 Bone and articular cartilage	0.005	0.995	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.995	0.005
E87.6 Hypokalaemia	0.000	0.995	0.005
E16 Other disorders of pancreatic internal secretion	0.005	0.995	0.000
C18.9 Colon, unspecified	0.005	0.995	0.000
E16.2 Hypoglycaemia, unspecified	0.005	0.995	0.000
E87.5 Hyperkalaemia	0.000	0.995	0.005
E16.0 Drug-induced hypoglycaemia without coma	0.005	0.995	0.000
E40-E46 Malnutrition	0.005	0.995	0.000
E87.7 Fluid overload	0.000	0.996	0.004
E15 Nondiabetic hypoglycaemic coma	0.004	0.996	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.996	0.004
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.996	0.004
E87.4 Mixed disorder of acid-base balance	0.000	0.996	0.004
E16.9 Disorder of pancreatic internal secretion, unspecified	0.004	0.996	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.004	0.996	0.000
E16.4 Abnormal secretion of gastrin	0.004	0.996	0.000
E16.3 Increased secretion of glucagon	0.004	0.996	0.000
E16.1 Other hypoglycaemia	0.004	0.996	0.000
N17.9 Acute renal failure, unspecified	0.000	0.996	0.004
E87.3 Alkalosis	0.000	0.996	0.004
K63.3 Ulcer of intestine	0.004	0.996	0.000
D44.3 Pituitary gland	0.004	0.996	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.004	0.996	0.000
S42.30 Fracture of shaft of humerus (closed)	0.004	0.996	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.996	0.004
E50-E64 Other nutritional deficiencies	0.004	0.996	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.996	0.004
E46 Unspecified protein-energy malnutrition	0.004	0.996	0.000
L43.9 Lichen planus, unspecified	0.004	0.996	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.996	0.004
E44 Protein-energy malnutrition of moderate and mild degree	0.003	0.996	0.000
E45 Retarded development following protein-energy malnutrition	0.003	0.996	0.000
E43 Unspecified severe protein-energy malnutrition	0.003	0.996	0.000
E42 Marasmic kwashiorkor	0.003	0.996	0.000
E41 Nutritional marasmus	0.003	0.996	0.000
E40 Kwashiorkor	0.003	0.996	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.996	0.004
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.004	0.996	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.004	0.996	0.000
D43.2 Brain, unspecified	0.003	0.996	0.000
E61 Deficiency of other nutrient elements	0.003	0.997	0.000
M47 Spondylosis	0.000	0.997	0.003
E10.5 With peripheral circulatory complications	0.003	0.997	0.000
I42.0 Dilated cardiomyopathy	0.003	0.997	0.000
E10-E14 Diabetes mellitus	0.003	0.997	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.000	0.997	0.003
M47.9 Spondylosis, unspecified	0.000	0.997	0.003
E10 Insulin-dependent diabetes mellitus	0.003	0.997	0.000
E61.1 Iron deficiency	0.003	0.997	0.000
D46 Myelodysplastic syndromes	0.003	0.997	0.000
D44.4 Craniopharyngeal duct	0.003	0.997	0.000
D44.0 Thyroid gland	0.003	0.997	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.003	0.997	0.000
E10.4 With neurological complications	0.003	0.997	0.000
D43.0 Brain, supratentorial	0.003	0.997	0.000
E10.0 With coma	0.003	0.997	0.000
N21.0 Calculus in bladder	0.003	0.997	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.000	0.997	0.003
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
E13 Other specified diabetes mellitus	0.003	0.997	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.000	0.997	0.003
M79.82 Other specified soft tissue disorders (Upper arm)	0.000	0.997	0.003
D46.7 Other myelodysplastic syndromes	0.003	0.997	0.000
D44.9 Endocrine gland, unspecified	0.003	0.997	0.000
D44.8 Pluriglandular involvement	0.003	0.997	0.000
D44.7 Aortic body and other paraganglia	0.003	0.997	0.000
D44.6 Carotid body	0.003	0.997	0.000
D44.5 Pineal gland	0.003	0.997	0.000
D44.2 Parathyroid gland	0.003	0.997	0.000
D44.1 Adrenal gland	0.003	0.997	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.003	0.997	0.000
E63 Other nutritional deficiencies	0.003	0.997	0.000
E56 Other vitamin deficiencies	0.003	0.997	0.000
E51 Thiamine deficiency	0.003	0.997	0.000
E50 Vitamin A deficiency	0.003	0.997	0.000
E60 Dietary zinc deficiency	0.003	0.997	0.000
E59 Dietary selenium deficiency	0.003	0.997	0.000
E58 Dietary calcium deficiency	0.003	0.997	0.000
E54 Ascorbic acid deficiency	0.003	0.997	0.000
E52 Niacin deficiency [pellagra]	0.003	0.997	0.000
S42.00 Fracture of clavicle (closed)	0.003	0.997	0.000
M79.8 Other specified soft tissue disorders	0.000	0.997	0.003
D46.2 Refractory anaemia with excess of blasts	0.003	0.997	0.000
E44.1 Mild protein-energy malnutrition	0.003	0.997	0.000
E44.0 Moderate protein-energy malnutrition	0.003	0.997	0.000
S42.3 Fracture of shaft of humerus	0.003	0.997	0.000
D40.1 Testis	0.003	0.997	0.000
D43.9 Central nervous system, unspecified	0.003	0.997	0.000
D43.7 Other parts of central nervous system	0.003	0.997	0.000
D43.4 Spinal cord	0.003	0.997	0.000
D43.3 Cranial nerves	0.003	0.997	0.000
D43.1 Brain, infratentorial	0.003	0.997	0.000
D47.1 Chronic myeloproliferative disease	0.003	0.997	0.000
E13.9 Without complications	0.003	0.997	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.003	0.997	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.000	0.997	0.003
E10.3 With ophthalmic complications	0.003	0.997	0.000
F60.3 Emotionally unstable personality disorder	0.000	0.997	0.003
M47.1 Other spondylosis with myelopathy	0.000	0.997	0.003
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.997	0.003
E61.9 Deficiency of nutrient element, unspecified	0.003	0.997	0.000
E61.8 Deficiency of other specified nutrient elements	0.003	0.997	0.000
E61.7 Deficiency of multiple nutrient elements	0.003	0.997	0.000
E61.6 Vanadium deficiency	0.003	0.997	0.000
E61.5 Molybdenum deficiency	0.003	0.997	0.000
E61.4 Chromium deficiency	0.003	0.997	0.000
E61.3 Manganese deficiency	0.003	0.997	0.000
E61.2 Magnesium deficiency	0.003	0.997	0.000
E61.0 Copper deficiency	0.003	0.997	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.000	0.997	0.003
E12 Malnutrition-related diabetes mellitus	0.003	0.997	0.000
E10.6 With other specified complications	0.003	0.997	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.000	0.997	0.003
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.000	0.997	0.003
M47.94 Spondylosis, unspecified (Thoracic region)	0.000	0.997	0.003
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.000	0.997	0.003
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.000	0.997	0.003
M79.88 Other specified soft tissue disorders (Other)	0.000	0.997	0.003
E10.7 With multiple complications	0.003	0.997	0.000
D47.2 Monoclonal gammopathy	0.003	0.997	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.003	0.997	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.002	0.997	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.002	0.997	0.000
D46.4 Refractory anaemia, unspecified	0.002	0.997	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.002	0.997	0.000
D46.1 Refractory anaemia with sideroblasts	0.002	0.997	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.002	0.997	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.997	0.002
F60.9 Personality disorder, unspecified	0.000	0.997	0.003
S42.0 Fracture of clavicle	0.003	0.997	0.000
E10.8 With unspecified complications	0.002	0.997	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.000	0.997	0.002
D40.9 Male genital organ, unspecified	0.002	0.997	0.000
D40.7 Other male genital organs	0.002	0.997	0.000
E10.2 With renal complications	0.002	0.997	0.000
D40.0 Prostate	0.002	0.997	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.002	0.997	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.997	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.002	0.997	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.002	0.997	0.000
E13.8 With unspecified complications	0.002	0.998	0.000
E13.7 With multiple complications	0.002	0.998	0.000
E13.6 With other specified complications	0.002	0.998	0.000
E13.5 With peripheral circulatory complications	0.002	0.998	0.000
E13.4 With neurological complications	0.002	0.998	0.000
E13.3 With ophthalmic complications	0.002	0.998	0.000
E13.2 With renal complications	0.002	0.998	0.000
E13.1 With ketoacidosis	0.002	0.998	0.000
E13.0 With coma	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.002	0.998	0.000
D47.4 Osteomyelofibrosis	0.002	0.998	0.000
L43 Lichen planus	0.002	0.998	0.000
E50.9 Vitamin A deficiency, unspecified	0.002	0.998	0.000
E50.8 Other manifestations of vitamin A deficiency	0.002	0.998	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.002	0.998	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.002	0.998	0.000
E50.5 Vitamin A deficiency with night blindness	0.002	0.998	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.002	0.998	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.002	0.998	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.002	0.998	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.002	0.998	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.002	0.998	0.000
E51.9 Thiamine deficiency, unspecified	0.002	0.998	0.000
E51.8 Other manifestations of thiamine deficiency	0.002	0.998	0.000
E51.2 Wernicke's encephalopathy	0.002	0.998	0.000
E51.1 Beriberi	0.002	0.998	0.000
E56.9 Vitamin deficiency, unspecified	0.002	0.998	0.000
E56.8 Deficiency of other vitamins	0.002	0.998	0.000
E56.1 Deficiency of vitamin K	0.002	0.998	0.000
E56.0 Deficiency of vitamin E	0.002	0.998	0.000
E63.9 Nutritional deficiency, unspecified	0.002	0.998	0.000
E63.8 Other specified nutritional deficiencies	0.002	0.998	0.000
E63.1 Imbalance of constituents of food intake	0.002	0.998	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.002	0.998	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.002	0.998	0.000
E64.8 Sequelae of other nutritional deficiencies	0.002	0.998	0.000
E64.3 Sequelae of rickets	0.002	0.998	0.000
E64.2 Sequelae of vitamin C deficiency	0.002	0.998	0.000
E64.1 Sequelae of vitamin A deficiency	0.002	0.998	0.000
E64.0 Sequelae of protein-energy malnutrition	0.002	0.998	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.000	0.998	0.002
J03.9 Acute tonsillitis, unspecified	0.000	0.998	0.002
S42.31 Fracture of shaft of humerus (open)	0.002	0.998	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.002	0.998	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.998	0.002
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.002	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
D42.9 Meninges, unspecified	0.002	0.998	0.000
D42.1 Spinal meninges	0.002	0.998	0.000
D42.0 Cerebral meninges	0.002	0.998	0.000
K91.4 Colostomy and enterostomy malfunction	0.002	0.998	0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.000	0.998	0.002
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.000	0.998	0.002
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.000	0.998	0.002
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.000	0.998	0.002
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.000	0.998	0.002
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.000	0.998	0.002
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.000	0.998	0.002
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.000	0.998	0.002
Z88.5 Personal history of allergy to narcotic agent	0.002	0.998	0.000
F60 Specific personality disorders	0.000	0.998	0.002
N36.2 Urethral caruncle	0.002	0.998	0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.000	0.998	0.002
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.000	0.998	0.002
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.000	0.998	0.002
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.000	0.998	0.002
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.000	0.998	0.002
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.000	0.998	0.002
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.000	0.998	0.002
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.000	0.998	0.002
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)	0.000	0.998	0.002
E10.1 With ketoacidosis	0.002	0.998	0.000
E12.9 Without complications	0.002	0.998	0.000
E12.8 With unspecified complications	0.002	0.998	0.000
E12.7 With multiple complications	0.002	0.998	0.000
E12.6 With other specified complications	0.002	0.998	0.000
E12.5 With peripheral circulatory complications	0.002	0.998	0.000
E12.4 With neurological complications	0.002	0.998	0.000
E12.3 With ophthalmic complications	0.002	0.998	0.000
E12.2 With renal complications	0.002	0.998	0.000
E12.1 With ketoacidosis	0.002	0.998	0.000
E12.0 With coma	0.002	0.998	0.000
L43.8 Other lichen planus	0.002	0.998	0.000
N36.8 Other specified disorders of urethra	0.002	0.998	0.000
E55 Vitamin D deficiency	0.002	0.998	0.000
S42 Fracture of shoulder and upper arm	0.002	0.998	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.002	0.998	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
E53 Deficiency of other B group vitamins	0.002	0.998	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.998	0.002
E65-E68 Obesity and other hyperalimentation	0.002	0.998	0.000
S42.01 Fracture of clavicle (open)	0.002	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.998	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
S42.1 Fracture of scapula	0.002	0.998	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
L43.3 Subacute (active) lichen planus	0.002	0.998	0.000
L43.2 Lichenoid drug reaction	0.002	0.998	0.000
L43.1 Bullous lichen planus	0.002	0.998	0.000
L43.0 Hypertrophic lichen planus	0.002	0.998	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.998	0.002
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.002	0.998	0.000
D39.9 Female genital organ, unspecified	0.002	0.998	0.000
D39.7 Other female genital organs	0.002	0.998	0.000
D39.2 Placenta	0.002	0.998	0.000
D39.0 Uterus	0.002	0.998	0.000
S42.10 Fracture of scapula (closed)	0.002	0.998	0.000
D38.6 Respiratory organ, unspecified	0.002	0.998	0.000
D38.5 Other respiratory organs	0.002	0.998	0.000
D38.4 Thymus	0.002	0.998	0.000
D38.3 Mediastinum	0.002	0.998	0.000
D38.2 Pleura	0.002	0.998	0.000
D38.0 Larynx	0.002	0.998	0.000
K14.9 Disease of tongue, unspecified	0.002	0.998	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.002	0.998	0.000
C18.1 Appendix	0.002	0.998	0.000
K91.1 Postgastric surgery syndromes	0.002	0.998	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.002	0.998	0.000
F60.8 Other specific personality disorders	0.000	0.998	0.002
F60.7 Dependent personality disorder	0.000	0.998	0.002
F60.5 Anankastic personality disorder	0.000	0.998	0.002
F60.4 Histrionic personality disorder	0.000	0.998	0.002
F60.2 Dissocial personality disorder	0.000	0.998	0.002
F60.1 Schizoid personality disorder	0.000	0.998	0.002
F60.0 Paranoid personality disorder	0.000	0.998	0.002
K25.3 Acute without haemorrhage or perforation	0.002	0.998	0.000
S01.2 Open wound of nose	0.002	0.998	0.000
E55.0 Rickets, active	0.002	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.002	0.998	0.000
H49 Paralytic strabismus	0.002	0.998	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
E53.9 Vitamin B deficiency, unspecified	0.002	0.998	0.000
H49.9 Paralytic strabismus, unspecified	0.002	0.998	0.000
X49.9 Unspecified place	0.002	0.998	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.000	0.998	0.002
E53.1 Pyridoxine deficiency	0.001	0.998	0.000
E53.0 Riboflavin deficiency	0.001	0.998	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.002	0.998	0.000
C18.0 Caecum	0.002	0.998	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
H49.2 Sixth [abducent] nerve palsy	0.002	0.998	0.000
E67 Other hyperalimentation	0.002	0.998	0.000
E68 Sequelae of hyperalimentation	0.002	0.998	0.000
F60.6 Anxious [avoidant] personality disorder	0.000	0.998	0.002
S42.4 Fracture of lower end of humerus	0.002	0.998	0.000
A49.0 Staphylococcal infection, unspecified	0.000	0.998	0.002
L71.9 Rosacea, unspecified	0.000	0.998	0.002
S42.11 Fracture of scapula (open)	0.002	0.998	0.000
D41.9 Urinary organ, unspecified	0.002	0.998	0.000
D41.7 Other urinary organs	0.002	0.998	0.000
D41.3 Urethra	0.002	0.998	0.000
D41.2 Ureter	0.002	0.998	0.000
D41.1 Renal pelvis	0.002	0.998	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.002	0.998	0.000
J35.0 Chronic tonsillitis	0.000	0.998	0.002
M54.64 Pain in thoracic spine (Thoracic region)	0.002	0.998	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.002	0.998	0.000
K91.5 Postcholecystectomy syndrome	0.002	0.998	0.000
R41.0 Disorientation, unspecified	0.000	0.998	0.002
F20.9 Schizophrenia, unspecified	0.000	0.998	0.002
K91.2 Postsurgical malabsorption, not elsewhere classified	0.002	0.998	0.000
N17 Acute renal failure	0.000	0.998	0.002
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.001	0.998	0.000
N36 Other disorders of urethra	0.002	0.998	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.001	0.998	0.000
D37.2 Small intestine	0.002	0.998	0.000
S22.40 Multiple fractures of ribs (closed)	0.002	0.998	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.002	0.998	0.000
C18 Malignant neoplasm of colon	0.002	0.998	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.002	0.998	0.000
B02.2 Zoster with other nervous system involvement	0.002	0.998	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.001	0.998	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.001	0.998	0.000
H49.8 Other paralytic strabismus	0.001	0.998	0.000
H49.4 Progressive external ophthalmoplegia	0.001	0.998	0.000
H49.3 Total (external) ophthalmoplegia	0.001	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
R60.0 Localised oedema	0.000	0.998	0.002
A41.8 Other specified septicaemia	0.000	0.998	0.002
E67.8 Other specified hyperalimentation	0.001	0.998	0.000
E67.3 Hypervitaminosis D	0.001	0.998	0.000
E67.2 Megavitamin-B6 syndrome	0.001	0.998	0.000
E67.1 Hypercarotenaemia	0.001	0.998	0.000
E67.0 Hypervitaminosis A	0.001	0.998	0.000
S42.41 Fracture of lower end of humerus (open)	0.001	0.998	0.000
A41.9 Septicaemia, unspecified	0.000	0.998	0.002
D37.4 Colon	0.002	0.998	0.000
D37.0 Lip, oral cavity and pharynx	0.001	0.998	0.000
A41 Other septicaemia	0.000	0.998	0.002
D38.1 Trachea, bronchus and lung	0.001	0.998	0.001
D41.0 Kidney	0.001	0.998	0.000
E03.8 Other specified hypothyroidism	0.002	0.998	0.000
Z90.1 Acquired absence of breast(s)	0.000	0.998	0.002
S62.40 Multiple fractures of metacarpal bones (closed)	0.001	0.998	0.000
K65.0 Acute peritonitis	0.002	0.998	0.000
N36.9 Urethral disorder, unspecified	0.001	0.998	0.000
Y84.6 Urinary catheterisation	0.000	0.998	0.002
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
H57.8 Other specified disorders of eye and adnexa	0.001	0.998	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.001	0.998	0.000
K65 Peritonitis	0.002	0.998	0.000
C18.8 Overlapping lesion of colon	0.001	0.998	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.001	0.998	0.000
L57.0 Actinic keratosis	0.002	0.998	0.000
M22.4 Chondromalacia patellae	0.001	0.998	0.000
N17.2 Acute renal failure with medullary necrosis	0.000	0.998	0.001
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.998	0.001
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.002	0.998	0.000
I42 Cardiomyopathy	0.002	0.998	0.000
D39.1 Ovary	0.001	0.999	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.001	0.999	0.000
N36.1 Urethral diverticulum	0.001	0.999	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.000	0.999	0.001
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.999	0.001
K90.0 Coeliac disease	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations