TreeWAS – Variant ID: rs9984110

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
I60-I69 Cerebrovascular diseases	1.000	0.000
Chapter V Mental and behavioural disorders	1.000	0.000
# Top node	1.000	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.999	0.001
I69 Sequelae of cerebrovascular disease	0.997	0.003
F40-F48 Neurotic, stress-related and somatoform disorders	0.995	0.005
F41 Other anxiety disorders	0.990	0.010
I70-I79 Diseases of arteries, arterioles and capillaries	0.989	0.011
F41.9 Anxiety disorder, unspecified	0.988	0.012
F30-F39 Mood [affective] disorders	0.987	0.013
I73 Other peripheral vascular diseases	0.987	0.013
I30-I52 Other forms of heart disease	0.985	0.015
I73.0 Raynaud's syndrome	0.980	0.020
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.979	0.021
F31 Bipolar affective disorder	0.974	0.026
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.973	0.027
S60-S69 Injuries to the wrist and hand	0.971	0.029
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.969	0.031
Chapter VIII Diseases of the ear and mastoid process	0.967	0.033
I60 Subarachnoid haemorrhage	0.954	0.046
I46 Cardiac arrest	0.952	0.048
Chapter VI Diseases of the nervous system	0.952	0.048
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.951	0.049
I35 Nonrheumatic aortic valve disorders	0.950	0.050
I49 Other cardiac arrhythmias	0.947	0.053
H60-H62 Diseases of external ear	0.939	0.061
F20 Schizophrenia	0.931	0.069
H90-H95 Other disorders of ear	0.929	0.071
F31.9 Bipolar affective disorder, unspecified	0.925	0.075
I35.1 Aortic (valve) insufficiency	0.919	0.081
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.913	0.087
H91 Other hearing loss	0.912	0.088
I46.0 Cardiac arrest with successful resuscitation	0.910	0.090
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.910	0.090
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.908	0.092
I49.9 Cardiac arrhythmia, unspecified	0.904	0.096
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.903	0.097
G90-G99 Other disorders of the nervous system	0.900	0.100
S80-S89 Injuries to the knee and lower leg	0.899	0.101
H91.9 Hearing loss, unspecified	0.896	0.104
I64 Stroke, not specified as haemorrhage or infarction	0.895	0.105
I69.1 Sequelae of intracerebral haemorrhage	0.894	0.106
I60.9 Subarachnoid haemorrhage, unspecified	0.891	0.109
Q38-Q45 Other congenital malformations of the digestive system	0.888	0.112
G91 Hydrocephalus	0.884	0.116
I73.9 Peripheral vascular disease, unspecified	0.880	0.120
H61 Other disorders of external ear	0.880	0.120
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.879	0.120
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.876	0.124
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.875	0.125
S40-S49 Injuries to the shoulder and upper arm	0.872	0.128
G91.9 Hydrocephalus, unspecified	0.872	0.128
F20.0 Paranoid schizophrenia	0.869	0.131
G00-G09 Inflammatory diseases of the central nervous system	0.868	0.132
S64 Injury of nerves at wrist and hand level	0.862	0.138
Q60-Q64 Congenital malformations of the urinary system	0.857	0.143
I61 Intracerebral haemorrhage	0.852	0.148
H60 Otitis externa	0.849	0.151
T43.0 Tricyclic and tetracyclic antidepressants	0.846	0.154
T51 Toxic effect of alcohol	0.844	0.156
G80-G83 Cerebral palsy and other paralytic syndromes	0.844	0.156
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.841	0.159
F99-F99 Unspecified mental disorder	0.838	0.162
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.837	0.163
S66 Injury of muscle and tendon at wrist and hand level	0.836	0.164
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.836	0.164
I95-I99 Other and unspecified disorders of the circulatory system	0.833	0.167
I73.8 Other specified peripheral vascular diseases	0.828	0.172
T39.1 4-Aminophenol derivatives	0.827	0.173
T43.3 Phenothiazine antipsychotics and neuroleptics	0.825	0.175
F25 Schizoaffective disorders	0.824	0.176
I77 Other disorders of arteries and arterioles	0.824	0.176
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.819	0.181
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.819	0.181
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.818	0.182
Q00-Q07 Congenital malformations of the nervous system	0.817	0.183
I69.3 Sequelae of cerebral infarction	0.816	0.184
T90 Sequelae of injuries of head	0.815	0.185
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.814	0.186
Q38 Other congenital malformations of tongue, mouth and pharynx	0.813	0.187
Q61 Cystic kidney disease	0.813	0.187
G30-G32 Other degenerative diseases of the nervous system	0.809	0.191
S60 Superficial injury of wrist and hand	0.807	0.193
I49.4 Other and unspecified premature depolarisation	0.806	0.194
I67 Other cerebrovascular diseases	0.804	0.196
S83.2 Tear of meniscus, current	0.803	0.197
F20.9 Schizophrenia, unspecified	0.803	0.197
S68 Traumatic amputation of wrist and hand	0.800	0.200
I46.9 Cardiac arrest, unspecified	0.800	0.200
H92 Otalgia and effusion of ear	0.799	0.201
I50 Heart failure	0.797	0.203
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.794	0.206
I49.3 Ventricular premature depolarisation	0.793	0.207
H61.8 Other specified disorders of external ear	0.789	0.211
F44 Dissociative [conversion] disorders	0.785	0.215
I98 Other disorders of circulatory system in diseases classified elsewhere	0.785	0.215
G95 Other diseases of spinal cord	0.784	0.216
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.779	0.221
H61.0 Perichondritis of external ear	0.776	0.224
I35.8 Other aortic valve disorders	0.776	0.224
Chapter XXII Codes for special purposes	0.776	0.224
I05-I09 Chronic rheumatic heart diseases	0.775	0.225
T46 Poisoning by agents primarily affecting the cardiovascular system	0.774	0.226
I50.9 Heart failure, unspecified	0.773	0.227
H61.1 Non-infective disorders of pinna	0.770	0.230
T66-T78 Other and unspecified effects of external causes	0.770	0.230
I35.9 Aortic valve disorder, unspecified	0.768	0.232
S62 Fracture at wrist and hand level	0.766	0.234
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.766	0.234
S10-S19 Injuries to the neck	0.765	0.235
F43 Reaction to severe stress, and adjustment disorders	0.765	0.235
T40.2 Other opioids	0.764	0.236
I45 Other conduction disorders	0.763	0.237
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.763	0.237
F48 Other neurotic disorders	0.763	0.237
G81 Hemiplegia	0.762	0.238
T91 Sequelae of injuries of neck and trunk	0.761	0.239
Q38.7 Pharyngeal pouch	0.760	0.240
I33 Acute and subacute endocarditis	0.756	0.244
F60-F69 Disorders of adult personality and behaviour	0.754	0.246
I77.1 Stricture of artery	0.754	0.246
S00-S09 Injuries to the head	0.753	0.247
F32 Depressive episode	0.753	0.247
Q61.0 Congenital single renal cyst	0.752	0.248
T51.0 Ethanol	0.750	0.250
I60.8 Other subarachnoid haemorrhage	0.748	0.252
I69.0 Sequelae of subarachnoid haemorrhage	0.746	0.254
I72 Other aneurysm	0.745	0.255
I98.2 Oesophageal varices in diseases classified elsewhere	0.745	0.255
T43.4 Butyrophenone and thioxanthene neuroleptics	0.743	0.257
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.741	0.258
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.740	0.259
G04 Encephalitis, myelitis and encephalomyelitis	0.739	0.261
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.739	0.261
H60.9 Otitis externa, unspecified	0.738	0.262
F41.2 Mixed anxiety and depressive disorder	0.737	0.263
F33 Recurrent depressive disorder	0.735	0.265
I49.5 Sick sinus syndrome	0.733	0.267
F29 Unspecified nonorganic psychosis	0.733	0.267
S60.9 Superficial injury of wrist and hand, unspecified	0.731	0.269
G70-G73 Diseases of myoneural junction and muscle	0.731	0.269
T43.5 Other and unspecified antipsychotics and neuroleptics	0.730	0.270
T51.9 Alcohol, unspecified	0.729	0.271
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.729	0.271
S64.2 Injury of radial nerve at wrist and hand level	0.729	0.271
S40 Superficial injury of shoulder and upper arm	0.729	0.271
T45.0 Antiallergic and antiemetic drugs	0.728	0.272
F30 Manic episode	0.728	0.272
I61.5 Intracerebral haemorrhage, intraventricular	0.727	0.273
F42 Obsessive-compulsive disorder	0.727	0.273
I30 Acute pericarditis	0.725	0.275
T42.4 Benzodiazepines	0.725	0.275
F41.1 Generalised anxiety disorder	0.723	0.277
S00 Superficial injury of head	0.722	0.278
F99 Mental disorder, not otherwise specified	0.722	0.278
S69 Other and unspecified injuries of wrist and hand	0.722	0.278
Q20-Q28 Congenital malformations of the circulatory system	0.721	0.279
I37 Pulmonary valve disorders	0.721	0.279
G82 Paraplegia and tetraplegia	0.718	0.282
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.718	0.282
T36 Poisoning by systemic antibiotics	0.718	0.282
F22 Persistent delusional disorders	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
I68 Cerebrovascular disorders in diseases classified elsewhere	0.717	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.717	0.283
F70-F79 Mental retardation	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.716	0.284
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.716	0.284
T41 Poisoning by anaesthetics and therapeutic gases	0.716	0.284
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.716	0.284
S64.3 Injury of digital nerve of thumb	0.715	0.284
I62 Other nontraumatic intracranial haemorrhage	0.715	0.285
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.714	0.285
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.713	0.287
T98 Sequelae of other and unspecified effects of external causes	0.712	0.288
F41.8 Other specified anxiety disorders	0.710	0.290
F41.3 Other mixed anxiety disorders	0.710	0.290
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.709	0.291
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.708	0.292
F38 Other mood [affective] disorders	0.707	0.292
F39 Unspecified mood [affective] disorder	0.707	0.292
I73.1 Thromboangiitis obliterans [Buerger]	0.707	0.292
S49 Other and unspecified injuries of shoulder and upper arm	0.707	0.293
S42 Fracture of shoulder and upper arm	0.707	0.293
I52 Other heart disorders in diseases classified elsewhere	0.707	0.293
I48 Atrial fibrillation and flutter	0.707	0.293
I43 Cardiomyopathy in diseases classified elsewhere	0.707	0.293
I41 Myocarditis in diseases classified elsewhere	0.707	0.293
I40 Acute myocarditis	0.707	0.293
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.707	0.293
I32 Pericarditis in diseases classified elsewhere	0.707	0.293
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.706	0.294
G91.2 Normal-pressure hydrocephalus	0.706	0.294
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.705	0.295
T20-T25 Burns and corrosions of external body surface, specified by site	0.703	0.297
H60.3 Other infective otitis externa	0.703	0.297
G81.9 Hemiplegia, unspecified	0.703	0.297
T42.0 Hydantoin derivatives	0.703	0.297
F25.0 Schizoaffective disorder, manic type	0.702	0.298
S62.5 Fracture of thumb	0.702	0.298
H91.3 Deaf mutism, not elsewhere classified	0.701	0.298
G03 Meningitis due to other and unspecified causes	0.700	0.299
F31.8 Other bipolar affective disorders	0.698	0.301
F31.7 Bipolar affective disorder, currently in remission	0.698	0.301
F31.6 Bipolar affective disorder, current episode mixed	0.698	0.301
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.698	0.301
F34 Persistent mood [affective] disorders	0.698	0.301
F45 Somatoform disorders	0.697	0.302
F28 Other nonorganic psychotic disorders	0.697	0.302
F24 Induced delusional disorder	0.697	0.302
F21 Schizotypal disorder	0.697	0.302
S00.9 Superficial injury of head, part unspecified	0.695	0.305
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.695	0.305
Q35-Q37 Cleft lip and cleft palate	0.695	0.305
Q30-Q34 Congenital malformations of the respiratory system	0.695	0.305
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.695	0.305
S67 Crushing injury of wrist and hand	0.691	0.309
G94 Other disorders of brain in diseases classified elsewhere	0.691	0.309
I74 Arterial embolism and thrombosis	0.691	0.309
I66.0 Occlusion and stenosis of middle cerebral artery	0.690	0.310
T92 Sequelae of injuries of upper limb	0.688	0.312
H91.8 Other specified hearing loss	0.688	0.312
S90-S99 Injuries to the ankle and foot	0.686	0.314
T94 Sequelae of injuries involving multiple and unspecified body regions	0.685	0.315
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.684	0.316
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.684	0.316
I60.5 Subarachnoid haemorrhage from vertebral artery	0.684	0.316
I60.4 Subarachnoid haemorrhage from basilar artery	0.684	0.316
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.684	0.316
H92.1 Otorrhoea	0.684	0.316
I31 Other diseases of pericardium	0.683	0.317
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.683	0.317
I46.1 Sudden cardiac death, so described	0.683	0.317
T43.9 Psychotropic drug, unspecified	0.682	0.318
T43.8 Other psychotropic drugs, not elsewhere classified	0.682	0.318
T43.6 Psychostimulants with abuse potential	0.682	0.318
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.682	0.318
I67.1 Cerebral aneurysm, nonruptured	0.682	0.318
S81 Open wound of lower leg	0.682	0.318
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.681	0.319
F23 Acute and transient psychotic disorders	0.680	0.319
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.680	0.320
Q05 Spina bifida	0.680	0.320
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.680	0.320
I49.2 Junctional premature depolarisation	0.679	0.321
F80-F89 Disorders of psychological development	0.679	0.321
G95.2 Cord compression, unspecified	0.678	0.321
Q39 Congenital malformations of oesophagus	0.678	0.322
H62 Disorders of external ear in diseases classified elsewhere	0.673	0.327
S65 Injury of blood vessels at wrist and hand level	0.673	0.327
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.672	0.327
T63 Toxic effect of contact with venomous animals	0.671	0.329
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.671	0.329
T90.2 Sequelae of fracture of skull and facial bones	0.669	0.331
F20.8 Other schizophrenia	0.667	0.333
F20.6 Simple schizophrenia	0.667	0.333
F20.5 Residual schizophrenia	0.667	0.333
F20.4 Postschizophrenic depression	0.667	0.333
F20.3 Undifferentiated schizophrenia	0.667	0.333
F20.2 Catatonic schizophrenia	0.667	0.333
F20.1 Hebephrenic schizophrenia	0.667	0.333
H94 Other disorders of ear in diseases classified elsewhere	0.666	0.334
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.665	0.334
S20-S29 Injuries to the thorax	0.665	0.335
S64.0 Injury of ulnar nerve at wrist and hand level	0.664	0.336
I35.2 Aortic (valve) stenosis with insufficiency	0.662	0.338
G40-G47 Episodic and paroxysmal disorders	0.661	0.339
T90.1 Sequelae of open wound of head	0.661	0.339
Q61.9 Cystic kidney disease, unspecified	0.661	0.339
T90.5 Sequelae of intracranial injury	0.660	0.340
T43.2 Other and unspecified antidepressants	0.660	0.340
T56 Toxic effect of metals	0.658	0.342
T11 Other injuries of upper limb, level unspecified	0.657	0.343
I45.4 Nonspecific intraventricular block	0.656	0.344
T91.9 Sequelae of unspecified injury of neck and trunk	0.656	0.344
H91.2 Sudden idiopathic hearing loss	0.654	0.346
H91.1 Presbycusis	0.654	0.346
H91.0 Ototoxic hearing loss	0.654	0.346
G09 Sequelae of inflammatory diseases of central nervous system	0.654	0.346
G31.9 Degenerative disease of nervous system, unspecified	0.653	0.347
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.653	0.347
G95.1 Vascular myelopathies	0.653	0.347
S46 Injury of muscle and tendon at shoulder and upper arm level	0.652	0.347
T46.5 Other antihypertensive drugs, not elsewhere classified	0.652	0.347
T95 Sequelae of burns, corrosions and frostbite	0.652	0.348
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.652	0.348
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.652	0.348
T65 Toxic effect of other and unspecified substances	0.651	0.349
T62 Toxic effect of other noxious substances eaten as food	0.651	0.349
T61 Toxic effect of noxious substances eaten as seafood	0.651	0.349
T60 Toxic effect of pesticides	0.651	0.349
T59 Toxic effect of other gases, fumes and vapours	0.651	0.349
T57 Toxic effect of other inorganic substances	0.651	0.349
T54 Toxic effect of corrosive substances	0.651	0.349
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.651	0.349
T52 Toxic effect of organic solvents	0.651	0.349
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.651	0.349
T55 Toxic effect of soaps and detergents	0.651	0.349
T90.9 Sequelae of unspecified injury of head	0.650	0.350
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.650	0.350
G06 Intracranial and intraspinal abscess and granuloma	0.649	0.351
T15-T19 Effects of foreign body entering through natural orifice	0.649	0.351
Q50-Q56 Congenital malformations of genital organs	0.648	0.351
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.648	0.352
T79-T79 Certain early complications of trauma	0.648	0.352
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.648	0.352
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.648	0.352
T42.5 Mixed antiepileptics, not elsewhere classified	0.648	0.352
T42.3 Barbiturates	0.648	0.352
T42.2 Succinimides and oxazolidinediones	0.648	0.352
T42.1 Iminostilbenes	0.648	0.352
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.647	0.353
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.647	0.353
I49.1 Atrial premature depolarisation	0.647	0.353
S50-S59 Injuries to the elbow and forearm	0.646	0.354
G98 Other disorders of nervous system, not elsewhere classified	0.645	0.355
G92 Toxic encephalopathy	0.645	0.355
S88 Traumatic amputation of lower leg	0.645	0.355
S87 Crushing injury of lower leg	0.645	0.355
S85 Injury of blood vessels at lower leg level	0.645	0.355
S84 Injury of nerves at lower leg level	0.645	0.355
F31.0 Bipolar affective disorder, current episode hypomanic	0.643	0.357
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.639	0.361
Q45 Other congenital malformations of digestive system	0.637	0.363
Q42 Congenital absence, atresia and stenosis of large intestine	0.637	0.363
Q41 Congenital absence, atresia and stenosis of small intestine	0.637	0.363
Q40 Other congenital malformations of upper alimentary tract	0.637	0.363
Q80-Q89 Other congenital malformations	0.635	0.364
F44.5 Dissociative convulsions	0.635	0.365
S42.2 Fracture of upper end of humerus	0.635	0.365
Q07 Other congenital malformations of nervous system	0.634	0.366
G91.8 Other hydrocephalus	0.634	0.366
G91.3 Posttraumatic hydrocephalus, unspecified	0.634	0.366
G91.0 Communicating hydrocephalus	0.634	0.366
S63.6 Sprain and strain of finger(s)	0.633	0.367
S62.50 Fracture of thumb (closed)	0.633	0.367
I36 Nonrheumatic tricuspid valve disorders	0.632	0.368
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.632	0.368
H61.9 Disorder of external ear, unspecified	0.631	0.369
I08 Multiple valve diseases	0.631	0.369
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.631	0.369
T38.9 Other and unspecified hormone antagonists	0.631	0.369
T38.8 Other and unspecified hormones and their synthetic substitutes	0.631	0.369
T38.7 Androgens and anabolic congeners	0.631	0.369
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.631	0.369
T38.5 Other oestrogens and progestogens	0.631	0.369
T38.4 Oral contraceptives	0.631	0.369
T38.2 Antithyroid drugs	0.631	0.369
T38.1 Thyroid hormones and substitutes	0.631	0.369
T38.0 Glucocorticoids and synthetic analogues	0.631	0.369
I67.0 Dissection of cerebral arteries, nonruptured	0.629	0.371
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.628	0.372
T39.4 Antirheumatics, not elsewhere classified	0.628	0.372
T39.2 Pyrazolone derivatives	0.628	0.372
I61.8 Other intracerebral haemorrhage	0.628	0.372
S83.7 Injury to multiple structures of knee	0.627	0.372
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.627	0.372
S83.3 Tear of articular cartilage of knee, current	0.627	0.372
S83.1 Dislocation of knee	0.627	0.372
S83.0 Dislocation of patella	0.627	0.372
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.626	0.374
S68.0 Traumatic amputation of thumb (complete)(partial)	0.626	0.374
S48 Traumatic amputation of shoulder and upper arm	0.625	0.374
S45 Injury of blood vessels at shoulder and upper arm level	0.625	0.374
S44 Injury of nerves at shoulder and upper arm level	0.625	0.374
S47 Crushing injury of shoulder and upper arm	0.625	0.374
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.625	0.375
Q43 Other congenital malformations of intestine	0.624	0.376
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.622	0.377
G00 Bacterial meningitis, not elsewhere classified	0.622	0.377
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.622	0.377
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.622	0.377
G01 Meningitis in bacterial diseases classified elsewhere	0.622	0.377
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.622	0.378
F25.9 Schizoaffective disorder, unspecified	0.620	0.379
T09 Other injuries of spine and trunk, level unspecified	0.619	0.380
S89 Other and unspecified injuries of lower leg	0.619	0.381
H60.1 Cellulitis of external ear	0.618	0.381
S00.0 Superficial injury of scalp	0.618	0.382
S64.9 Injury of unspecified nerve at wrist and hand level	0.618	0.382
S64.8 Injury of other nerves at wrist and hand level	0.618	0.382
S64.7 Injury of multiple nerves at wrist and hand level	0.618	0.382
S64.1 Injury of median nerve at wrist and hand level	0.618	0.382
H92.0 Otalgia	0.615	0.385
Q64 Other congenital malformations of urinary system	0.614	0.386
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.614	0.386
Q61.2 Polycystic kidney, adult type	0.613	0.386
F43.1 Posttraumatic stress disorder	0.613	0.387
S83.6 Sprain and strain of other and unspecified parts of knee	0.612	0.388
G31.8 Other specified degenerative diseases of nervous system	0.612	0.388
I61.6 Intracerebral haemorrhage, multiple localised	0.611	0.389
I61.4 Intracerebral haemorrhage in cerebellum	0.611	0.389
I61.3 Intracerebral haemorrhage in brain stem	0.611	0.389
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.611	0.389
S41 Open wound of shoulder and upper arm	0.610	0.390
T13 Other injuries of lower limb, level unspecified	0.610	0.390
G35-G37 Demyelinating diseases of the central nervous system	0.609	0.391
T58 Toxic effect of carbon monoxide	0.609	0.391
I72.9 Aneurysm of unspecified site	0.609	0.391
H60.8 Other otitis externa	0.609	0.391
H60.5 Acute otitis externa, non-infective	0.609	0.391
H60.4 Cholesteatoma of external ear	0.609	0.391
H60.2 Malignant otitis externa	0.609	0.391
H60.0 Abscess of external ear	0.609	0.391
Q61.3 Polycystic kidney, unspecified	0.608	0.392
F32.0 Mild depressive episode	0.608	0.392
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.605	0.394
T51.8 Other alcohols	0.605	0.395
T51.3 Fusel oil	0.605	0.395
T51.2 2-Propanol	0.605	0.395
T51.1 Methanol	0.605	0.395
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.603	0.397
T45.9 Primarily systemic and haematological agent, unspecified	0.603	0.397
T45.8 Other primarily systemic and haematological agents	0.603	0.397
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.603	0.397
T45.6 Fibrinolysis-affecting drugs	0.603	0.397
T45.5 Anticoagulants	0.603	0.397
T45.4 Iron and its compounds	0.603	0.397
T45.3 Enzymes, not elsewhere classified	0.603	0.397
T45.2 Vitamins, not elsewhere classified	0.603	0.397
T45.1 Antineoplastic and immunosuppressive drugs	0.603	0.397
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.601	0.399
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.600	0.400
T40.8 Lysergide [LSD]	0.600	0.400
T40.7 Cannabis (derivatives)	0.600	0.400
T40.5 Cocaine	0.600	0.400
T40.3 Methadone	0.600	0.400
T40.1 Heroin	0.600	0.400
T40.0 Opium	0.600	0.400
T92.1 Sequelae of fracture of arm	0.600	0.400
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.600	0.400
S66.8 Injury of other muscles and tendons at wrist and hand level	0.600	0.400
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.600	0.400
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.600	0.400
T66 Unspecified effects of radiation	0.598	0.401
T75 Effects of other external causes	0.598	0.402
F48.0 Neurasthenia	0.597	0.403
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.597	0.403
G82.1 Spastic paraplegia	0.596	0.404
G40 Epilepsy	0.595	0.405
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.594	0.406
I72.0 Aneurysm of carotid artery	0.594	0.406
T90.8 Sequelae of other specified injuries of head	0.594	0.406
I49.8 Other specified cardiac arrhythmias	0.592	0.407
I45.9 Conduction disorder, unspecified	0.592	0.408
I33.0 Acute and subacute infective endocarditis	0.591	0.409
F25.8 Other schizoaffective disorders	0.591	0.409
F25.2 Schizoaffective disorder, mixed type	0.591	0.409
F25.1 Schizoaffective disorder, depressive type	0.591	0.409
I77.5 Necrosis of artery	0.590	0.409
I77.4 Coeliac artery compression syndrome	0.590	0.409
I77.3 Arterial fibromuscular dysplasia	0.590	0.409
I77.2 Rupture of artery	0.590	0.409
S86 Injury of muscle and tendon at lower leg level	0.589	0.411
S49.9 Unspecified injury of shoulder and upper arm	0.589	0.411
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.587	0.412
I66.8 Occlusion and stenosis of other cerebral artery	0.587	0.412
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.587	0.412
I66.3 Occlusion and stenosis of cerebellar arteries	0.587	0.412
I66.2 Occlusion and stenosis of posterior cerebral artery	0.587	0.412
I66.1 Occlusion and stenosis of anterior cerebral artery	0.587	0.412
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.587	0.413
I47 Paroxysmal tachycardia	0.587	0.413
I09 Other rheumatic heart diseases	0.587	0.413
Q06 Other congenital malformations of spinal cord	0.586	0.414
Q04 Other congenital malformations of brain	0.586	0.414
Q03 Congenital hydrocephalus	0.586	0.414
Q01 Encephalocele	0.586	0.414
Q00 Anencephaly and similar malformations	0.586	0.414
Q02 Microcephaly	0.586	0.414
S81.8 Open wound of other parts of lower leg	0.585	0.415
S29 Other and unspecified injuries of thorax	0.584	0.415
T90.3 Sequelae of injury of cranial nerves	0.584	0.416
T90.0 Sequelae of superficial injury of head	0.584	0.416
T12.X1 Fracture of lower limb, level unspecified (open)	0.584	0.416
T12.X0 Fracture of lower limb, level unspecified (closed)	0.584	0.416
T12 Fracture of lower limb, level unspecified	0.584	0.416
T10.X1 Fracture of upper limb, level unspecified (open)	0.584	0.416
T10.X0 Fracture of upper limb, level unspecified (closed)	0.584	0.416
T10 Fracture of upper limb, level unspecified	0.584	0.416
T08.X1 Fracture of spine, level unspecified (open)	0.584	0.416
T08.X0 Fracture of spine, level unspecified (closed)	0.584	0.416
T08 Fracture of spine, level unspecified	0.584	0.416
S42.20 Fracture of upper end of humerus (closed)	0.584	0.416
F32.2 Severe depressive episode without psychotic symptoms	0.583	0.417
Q38.8 Other congenital malformations of pharynx	0.583	0.417
Q38.6 Other congenital malformations of mouth	0.583	0.417
Q38.5 Congenital malformations of palate, not elsewhere classified	0.583	0.417
Q38.4 Congenital malformations of salivary glands and ducts	0.583	0.417
Q38.3 Other congenital malformations of tongue	0.583	0.417
Q38.2 Macroglossia	0.583	0.417
Q38.1 Ankyloglossia	0.583	0.417
Q38.0 Congenital malformations of lips, not elsewhere classified	0.583	0.417
Q61.8 Other cystic kidney diseases	0.583	0.417

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations