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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0269
log Bayes Factor = 155.455
contains 9 variants:
rs362307
lBF = 11.877
Chr 4 : 3,241,845
rs12508440
lBF = 5.684
Chr 4 : 62,487,133
rs62355136
lBF = 13.162
Chr 5 : 30,714,599
rs115154880
lBF = 8.201
Chr 5 : 43,883,949
rs6973517
lBF = 6.618
Chr 7 : 122,507,282
rs79987207
lBF = 5.416
Chr 9 : 100,963,977
rs11174454
lBF = 8.973
Chr12 : 62,781,002
rs111825271
lBF = 10.547
Chr12 : 66,344,706
rs17472393
lBF = 7.451
Chr13 : 100,056,531
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
1.000 0.000 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
1.000 0.000 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
H65-H75 Diseases of middle ear and mastoid
1.000 0.000 0.000
J09-J18 Influenza and pneumonia
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
M86-M90 Other osteopathies
1.000 0.000 0.000
N00-N08 Glomerular diseases
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
M54.9 Dorsalgia, unspecified
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
J43 Emphysema
1.000 0.000 0.000
F60-F69 Disorders of adult personality and behaviour
1.000 0.000 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
E14.9 Without complications
1.000 0.000 0.000
M89 Other disorders of bone
1.000 0.000 0.000
F60 Specific personality disorders
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
M79 Other soft tissue disorders, not elsewhere classified
1.000 0.000 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
1.000 0.000 0.000
M54 Dorsalgia
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M80-M85 Disorders of bone density and structure
1.000 0.000 0.000
J43.9 Emphysema, unspecified
1.000 0.000 0.000
J44.8 Other specified chronic obstructive pulmonary disease
1.000 0.000 0.000
M86 Osteomyelitis
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
M46 Other inflammatory spondylopathies
0.999 0.001 0.000
S90-S99 Injuries to the ankle and foot
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.999 0.001 0.000
N04 Nephrotic syndrome
0.999 0.001 0.000
E20-E35 Disorders of other endocrine glands
0.999 0.001 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.999 0.001 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.999 0.001 0.000
N04.9 Unspecified
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
F60.9 Personality disorder, unspecified
0.999 0.001 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.999 0.001 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.999 0.001 0.000
T43.2 Other and unspecified antidepressants
0.998 0.002 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.998 0.002 0.000
E11.3 With ophthalmic complications
0.998 0.002 0.000
E11.2 With renal complications
0.998 0.002 0.000
E16 Other disorders of pancreatic internal secretion
0.998 0.002 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.998 0.002 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.998 0.002 0.000
H74 Other disorders of middle ear and mastoid
0.998 0.002 0.000
E50-E64 Other nutritional deficiencies
0.997 0.003 0.000
A30-A49 Other bacterial diseases
0.997 0.003 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.997 0.003 0.000
M86.9 Osteomyelitis, unspecified
0.997 0.003 0.000
M89.8 Other specified disorders of bone
0.997 0.003 0.000
S50-S59 Injuries to the elbow and forearm
0.996 0.004 0.000
M80 Osteoporosis with pathological fracture
0.996 0.004 0.000
N05 Unspecified nephritic syndrome
0.996 0.004 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.996 0.004 0.000
A40 Streptococcal septicaemia
0.996 0.004 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.995 0.005 0.000
E28 Ovarian dysfunction
0.995 0.005 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.995 0.005 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.994 0.006 0.000
G70-G73 Diseases of myoneural junction and muscle
0.994 0.006 0.000
T23 Burn and corrosion of wrist and hand
0.994 0.006 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.993 0.007 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.993 0.007 0.000
E16.2 Hypoglycaemia, unspecified
0.993 0.007 0.000
J10 Influenza due to identified influenza virus
0.993 0.007 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.992 0.008 0.000
V80-V89 Other land transport accidents
0.992 0.008 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.991 0.009 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.990 0.010 0.000
D00-D09 In situ neoplasms
0.990 0.010 0.000
E11.8 With unspecified complications
0.989 0.011 0.000
N25-N29 Other disorders of kidney and ureter
0.989 0.011 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.988 0.012 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.988 0.012 0.000
Y44 Agents primarily affecting blood constituents
0.988 0.012 0.000
M79.2 Neuralgia and neuritis, unspecified
0.988 0.012 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.987 0.013 0.000
M79.69 Pain in limb (Site unspecified)
0.987 0.013 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.987 0.013 0.000
M79.6 Pain in limb
0.987 0.013 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.986 0.014 0.000
J86 Pyothorax
0.986 0.014 0.000
S90 Superficial injury of ankle and foot
0.985 0.015 0.000
F60.3 Emotionally unstable personality disorder
0.985 0.015 0.000
C91 Lymphoid leukaemia
0.985 0.015 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.984 0.016 0.000
S54 Injury of nerves at forearm level
0.984 0.016 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.983 0.017 0.000
Q80-Q89 Other congenital malformations
0.983 0.017 0.000
T66-T78 Other and unspecified effects of external causes
0.983 0.017 0.000
M45 Ankylosing spondylitis
0.981 0.019 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.981 0.019 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.981 0.019 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.981 0.019 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.980 0.020 0.000
T56 Toxic effect of metals
0.980 0.020 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.979 0.021 0.000
Y44.2 Anticoagulants
0.979 0.021 0.000
M79.1 Myalgia
0.979 0.021 0.000
H71 Cholesteatoma of middle ear
0.979 0.021 0.000
W50-W64 Exposure to animate mechanical forces
0.979 0.021 0.000
M21 Other acquired deformities of limbs
0.978 0.022 0.000
B02 Zoster [herpes zoster]
0.978 0.022 0.000
E27 Other disorders of adrenal gland
0.977 0.023 0.000
H72 Perforation of tympanic membrane
0.977 0.023 0.000
W20-W49 Exposure to inanimate mechanical forces
0.977 0.023 0.000
H90-H95 Other disorders of ear
0.976 0.024 0.000
C45 Mesothelioma
0.976 0.024 0.000
S10-S19 Injuries to the neck
0.976 0.024 0.000
N26 Unspecified contracted kidney
0.975 0.025 0.000
M15-M19 Arthrosis
0.974 0.026 0.000
T17 Foreign body in respiratory tract
0.974 0.026 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.973 0.027 0.000
J43.2 Centrilobular emphysema
0.973 0.027 0.000
E28.2 Polycystic ovarian syndrome
0.973 0.027 0.000
G71 Primary disorders of muscles
0.972 0.028 0.000
A40.8 Other streptococcal septicaemia
0.972 0.028 0.000
J18 Pneumonia, organism unspecified
0.971 0.029 0.000
J15.1 Pneumonia due to Pseudomonas
0.971 0.029 0.000
M19.0 Primary arthrosis of other joints
0.971 0.029 0.000
M19 Other arthrosis
0.971 0.029 0.000
J84 Other interstitial pulmonary diseases
0.970 0.030 0.000
B99-B99 Other infectious diseases
0.970 0.030 0.000
T56.8 Other metals
0.969 0.031 0.000
A40.9 Streptococcal septicaemia, unspecified
0.968 0.032 0.000
V20-V29 Motorcycle rider injured in transport accident
0.968 0.032 0.000
N05.9 Unspecified
0.968 0.032 0.000
M21.0 Valgus deformity, not elsewhere classified
0.968 0.032 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.967 0.033 0.000
M87 Osteonecrosis
0.966 0.034 0.000
M48 Other spondylopathies
0.966 0.034 0.000
D04 Carcinoma in situ of skin
0.965 0.035 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.965 0.035 0.000
X60-X84 Intentional self-harm
0.964 0.036 0.000
E10 Insulin-dependent diabetes mellitus
0.964 0.036 0.000
W00-W19 Falls
0.964 0.036 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.963 0.037 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.963 0.037 0.000
E55 Vitamin D deficiency
0.963 0.037 0.000
M89.0 Algoneurodystrophy
0.962 0.038 0.000
E61 Deficiency of other nutrient elements
0.962 0.038 0.000
M25 Other joint disorders, not elsewhere classified
0.962 0.038 0.000
M30 Polyarteritis nodosa and related conditions
0.961 0.039 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.961 0.039 0.000
S56 Injury of muscle and tendon at forearm level
0.960 0.040 0.000
T00-T07 Injuries involving multiple body regions
0.959 0.041 0.000
M49 Spondylopathies in diseases classified elsewhere
0.959 0.041 0.000
T75 Effects of other external causes
0.959 0.041 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.959 0.041 0.000
J10.0 Influenza with pneumonia, influenza virus identified
0.958 0.042 0.000
V89.9 Person injured in unspecified vehicle accident
0.957 0.043 0.000
M54.4 Lumbago with sciatica
0.957 0.043 0.000
E28.3 Primary ovarian failure
0.956 0.044 0.000
F30-F39 Mood [affective] disorders
0.956 0.044 0.000
S92 Fracture of foot, except ankle
0.955 0.045 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.955 0.045 0.000
J86.9 Pyothorax without fistula
0.954 0.046 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.953 0.047 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.952 0.048 0.000
M77 Other enthesopathies
0.952 0.048 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.951 0.049 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.950 0.050 0.000
C84.4 Peripheral T-cell lymphoma
0.950 0.050 0.000
H74.1 Adhesive middle ear disease
0.949 0.051 0.000
B99 Other and unspecified infectious diseases
0.949 0.051 0.000
H93 Other disorders of ear, not elsewhere classified
0.948 0.052 0.000
J18.0 Bronchopneumonia, unspecified
0.947 0.053 0.000
N10-N16 Renal tubulo-interstitial diseases
0.947 0.053 0.000
C45.7 Mesothelioma of other sites
0.947 0.053 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.946 0.054 0.000
M86.6 Other chronic osteomyelitis
0.946 0.054 0.000
M25.4 Effusion of joint
0.945 0.055 0.000
J84.8 Other specified interstitial pulmonary diseases
0.945 0.055 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.944 0.056 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.943 0.057 0.000
D07.1 Vulva
0.943 0.057 0.000
T75.4 Effects of electric current
0.942 0.058 0.000
S31 Open wound of abdomen, lower back and pelvis
0.941 0.059 0.000
S54.1 Injury of median nerve at forearm level
0.940 0.060 0.000
V40-V49 Car occupant injured in transport accident
0.940 0.060 0.000
M82 Osteoporosis in diseases classified elsewhere
0.940 0.060 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.939 0.061 0.000
T18 Foreign body in alimentary tract
0.939 0.061 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.938 0.062 0.000
E55.9 Vitamin D deficiency, unspecified
0.938 0.062 0.000
J17 Pneumonia in diseases classified elsewhere
0.938 0.062 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.938 0.062 0.000
M89.3 Hypertrophy of bone
0.937 0.063 0.000
M05-M14 Inflammatory polyarthropathies
0.937 0.063 0.000
E14.4 With neurological complications
0.936 0.064 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.936 0.064 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.936 0.064 0.000
J86.0 Pyothorax with fistula
0.935 0.065 0.000
T68 Hypothermia
0.934 0.066 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.934 0.066 0.000
E11.0 With coma
0.934 0.066 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.933 0.067 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.933 0.067 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.932 0.068 0.000
H93.8 Other specified disorders of ear
0.932 0.068 0.000
H65 Nonsuppurative otitis media
0.932 0.068 0.000
N05.1 Focal and segmental glomerular lesions
0.932 0.068 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.931 0.069 0.000
F33 Recurrent depressive disorder
0.931 0.069 0.000
M76 Enthesopathies of lower limb, excluding foot
0.931 0.069 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.931 0.069 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.930 0.070 0.000
C91.4 Hairy-cell leukaemia
0.930 0.070 0.000
E16.1 Other hypoglycaemia
0.930 0.070 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.929 0.071 0.000
J18.8 Other pneumonia, organism unspecified
0.928 0.072 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.928 0.072 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.927 0.073 0.000
W17 Other fall from one level to another
0.927 0.073 0.000
M34 Systemic sclerosis
0.927 0.073 0.000
M25.3 Other instability of joint
0.926 0.074 0.000
Y00-Y09 Assault
0.926 0.074 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.925 0.075 0.000
H60-H62 Diseases of external ear
0.924 0.076 0.000
S54.0 Injury of ulnar nerve at forearm level
0.924 0.076 0.000
H72.8 Other perforations of tympanic membrane
0.924 0.076 0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.923 0.077 0.000
B02.2 Zoster with other nervous system involvement
0.923 0.077 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.923 0.077 0.000
N27 Small kidney of unknown cause
0.923 0.077 0.000
H66 Suppurative and unspecified otitis media
0.922 0.078 0.000
M87.9 Osteonecrosis, unspecified
0.922 0.078 0.000
B15-B19 Viral hepatitis
0.922 0.078 0.000
C84.5 Other and unspecified T-cell lymphomas
0.922 0.078 0.000
D07.4 Penis
0.921 0.079 0.000
M21.2 Flexion deformity
0.921 0.079 0.000
G90-G99 Other disorders of the nervous system
0.920 0.080 0.000
M79.60 Pain in limb (Multiple sites)
0.920 0.080 0.000
N99-N99 Other disorders of the genitourinary system
0.920 0.080 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.920 0.080 0.000
E27.9 Disorder of adrenal gland, unspecified
0.920 0.080 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.919 0.081 0.000
X69.9 Unspecified place
0.919 0.081 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.918 0.082 0.000
W20 Struck by thrown, projected or falling object
0.918 0.082 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.917 0.083 0.000
Q82 Other congenital malformations of skin
0.916 0.084 0.000
M89.88 Other specified disorders of bone (Other)
0.916 0.084 0.000
X10-X19 Contact with heat and hot substances
0.916 0.084 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.915 0.085 0.000
J15.4 Pneumonia due to other streptococci
0.915 0.085 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.915 0.085 0.000
E20 Hypoparathyroidism
0.915 0.085 0.000
C32 Malignant neoplasm of larynx
0.914 0.086 0.000
T23.3 Burn of third degree of wrist and hand
0.914 0.086 0.000
E61.1 Iron deficiency
0.913 0.087 0.000
E10.2 With renal complications
0.912 0.088 0.000
T20 Burn and corrosion of head and neck
0.911 0.089 0.000
B02.3 Zoster ocular disease
0.911 0.089 0.000
Y60.0 During surgical operation
0.911 0.089 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.911 0.089 0.000
V10-V19 Pedal cyclist injured in transport accident
0.911 0.089 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.908 0.092 0.000
H60 Otitis externa
0.908 0.092 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.908 0.092 0.000
E10.8 With unspecified complications
0.908 0.092 0.000
M84 Disorders of continuity of bone
0.907 0.093 0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.907 0.093 0.000
W29 Contact with other powered hand tools and household machinery
0.906 0.094 0.000
A15-A19 Tuberculosis
0.906 0.094 0.000
N17-N19 Renal failure
0.905 0.095 0.000
L60-L75 Disorders of skin appendages
0.905 0.095 0.000
E27.1 Primary adrenocortical insufficiency
0.905 0.095 0.000
M60-M63 Disorders of muscles
0.905 0.095 0.000
L10-L14 Bullous disorders
0.905 0.095 0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot
0.904 0.096 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.904 0.096 0.000
E65-E68 Obesity and other hyperalimentation
0.902 0.098 0.000
T17.5 Foreign body in bronchus
0.902 0.098 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.902 0.098 0.000
D07.2 Vagina
0.901 0.099 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.901 0.099 0.000
M40-M43 Deforming dorsopathies
0.901 0.099 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.901 0.099 0.000
M91-M94 Chondropathies
0.900 0.100 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.900 0.100 0.000
G70 Myasthenia gravis and other myoneural disorders
0.900 0.100 0.000
G71.1 Myotonic disorders
0.899 0.101 0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)
0.899 0.101 0.000
M82.1 Osteoporosis in endocrine disorders
0.897 0.103 0.000
S20-S29 Injuries to the thorax
0.896 0.104 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.895 0.105 0.000
F69 Unspecified disorder of adult personality and behaviour
0.895 0.105 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.895 0.105 0.000
H72.0 Central perforation of tympanic membrane
0.895 0.105 0.000
G71.3 Mitochondrial myopathy, not elsewhere classified
0.894 0.106 0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)
0.893 0.107 0.000
M79.15 Myalgia (Pelvic region and thigh)
0.893 0.107 0.000
C91.9 Lymphoid leukaemia, unspecified
0.892 0.108 0.000
C49.9 Connective and soft tissue, unspecified
0.891 0.109 0.000
B02.8 Zoster with other complications
0.891 0.109 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.890 0.110 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.890 0.110 0.000
W55 Bitten or struck by other mammals
0.890 0.110 0.000
S92.5 Fracture of other toe
0.890 0.110 0.000
F30 Manic episode
0.890 0.110 0.000
A39 Meningococcal infection
0.890 0.110 0.000
Y48 Anaesthetics and therapeutic gases
0.889 0.111 0.000
S90.8 Other superficial injuries of ankle and foot
0.889 0.111 0.000
M10 Gout
0.889 0.111 0.000
Q43 Other congenital malformations of intestine
0.889 0.111 0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)
0.889 0.111 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.888 0.112 0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)
0.888 0.112 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.888 0.112 0.000
J90-J94 Other diseases of pleura
0.887 0.113 0.000
J94 Other pleural conditions
0.887 0.113 0.000
S92.7 Multiple fractures of foot
0.887 0.113 0.000
T23.2 Burn of second degree of wrist and hand
0.886 0.114 0.000
G06.0 Intracranial abscess and granuloma
0.886 0.114 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.886 0.114 0.000
M25.43 Effusion of joint (Forearm)
0.885 0.115 0.000
H69 Other disorders of Eustachian tube
0.884 0.116 0.000
J94.8 Other specified pleural conditions
0.884 0.116 0.000
T91 Sequelae of injuries of neck and trunk
0.882 0.118 0.000
G57 Mononeuropathies of lower limb
0.882 0.118 0.000
Y49.5 Other antipsychotics and neuroleptics
0.881 0.119 0.000
F33.9 Recurrent depressive disorder, unspecified
0.881 0.119 0.000
T18.5 Foreign body in anus and rectum
0.881 0.119 0.000
G53.0 Postzoster neuralgia
0.880 0.120 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.880 0.120 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.879 0.121 0.000
Q65 Congenital deformities of hip
0.879 0.121 0.000
Y57 Other and unspecified drugs and medicaments
0.879 0.121 0.000
B25-B34 Other viral diseases
0.879 0.121 0.000
M00-M03 Infectious arthropathies
0.878 0.122 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.878 0.122 0.000
S90.1 Contusion of toe(s) without damage to nail
0.878 0.122 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.878 0.122 0.000
Y65 Other misadventures during surgical and medical care
0.877 0.123 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.877 0.123 0.000
N19 Unspecified renal failure
0.876 0.124 0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level
0.876 0.124 0.000
Q78 Other osteochondrodysplasias
0.876 0.124 0.000
E10.6 With other specified complications
0.876 0.124 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.875 0.125 0.000
Q76 Congenital malformations of spine and bony thorax
0.875 0.125 0.000
T01 Open wounds involving multiple body regions
0.875 0.125 0.000
S90.0 Contusion of ankle
0.875 0.125 0.000
T58 Toxic effect of carbon monoxide
0.875 0.125 0.000
M79.7 Fibromyalgia
0.874 0.126 0.000
E53 Deficiency of other B group vitamins
0.874 0.126 0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.874 0.126 0.000
M24 Other specific joint derangements
0.872 0.128 0.000
G00 Bacterial meningitis, not elsewhere classified
0.871 0.129 0.000
V98-V99 Other and unspecified transport accidents
0.871 0.129 0.000
D04.5 Skin of trunk
0.870 0.130 0.000
F50 Eating disorders
0.870 0.130 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.869 0.131 0.000
N05.2 Diffuse membranous glomerulonephritis
0.869 0.131 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.869 0.131 0.000
S10 Superficial injury of neck
0.869 0.131 0.000
E11.1 With ketoacidosis
0.869 0.131 0.000
A40.0 Septicaemia due to streptococcus, group A
0.868 0.132 0.000
M25.9 Joint disorder, unspecified
0.868 0.132 0.000
Q82.8 Other specified congenital malformations of skin
0.868 0.132 0.000
A49 Bacterial infection of unspecified site
0.867 0.133 0.000
M54.8 Other dorsalgia
0.867 0.133 0.000
M84.0 Malunion of fracture
0.867 0.133 0.000
M89.04 Algoneurodystrophy (Hand)
0.867 0.133 0.000
M15 Polyarthrosis
0.867 0.133 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.867 0.133 0.000
T21 Burn and corrosion of trunk
0.866 0.134 0.000
J95-J99 Other diseases of the respiratory system
0.865 0.135 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.865 0.135 0.000
Q66 Congenital deformities of feet
0.865 0.135 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.864 0.136 0.000
L20-L30 Dermatitis and eczema
0.864 0.136 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.864 0.136 0.000
W17.4 Street and highway
0.863 0.137 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.863 0.137 0.000
W20.0 Home
0.863 0.137 0.000
F64 Gender identity disorders
0.862 0.137 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.862 0.138 0.000
F80-F89 Disorders of psychological development
0.862 0.138 0.000
C49.5 Connective and soft tissue of pelvis
0.861 0.139 0.000
Q39 Congenital malformations of oesophagus
0.861 0.139 0.000
C81 Hodgkin's disease
0.861 0.139 0.000
F60.7 Dependent personality disorder
0.861 0.139 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.860 0.140 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.860 0.140 0.000
L70 Acne
0.859 0.141 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.858 0.142 0.000
M89.81 Other specified disorders of bone (Shoulder region)
0.857 0.143 0.000
C91.0 Acute lymphoblastic leukaemia
0.857 0.143 0.000
S31.4 Open wound of vagina and vulva
0.857 0.143 0.000
M30.0 Polyarteritis nodosa
0.856 0.144 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.855 0.145 0.000
E20.9 Hypoparathyroidism, unspecified
0.855 0.145 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.854 0.146 0.000
T20.1 Burn of first degree of head and neck
0.853 0.147 0.000
J43.8 Other emphysema
0.853 0.147 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.853 0.147 0.000
E14.3 With ophthalmic complications
0.853 0.147 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.853 0.147 0.000
M54.2 Cervicalgia
0.853 0.147 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.853 0.147 0.000
C32.9 Larynx, unspecified
0.851 0.149 0.000
B50-B64 Protozoal diseases
0.850 0.150 0.000
H95.1 Other disorders following mastoidectomy
0.850 0.150 0.000
V28.9 Unspecified motorcycle rider injured in traffic accident
0.850 0.150 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.849 0.151 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.849 0.151 0.000
T79-T79 Certain early complications of trauma
0.849 0.151 0.000
T17.2 Foreign body in pharynx
0.848 0.152 0.000
S36 Injury of intra-abdominal organs
0.847 0.153 0.000
H66.3 Other chronic suppurative otitis media
0.846 0.154 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.846 0.154 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.846 0.154 0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level
0.846 0.154 0.000
H72.1 Attic perforation of tympanic membrane
0.845 0.155 0.000
C73 Malignant neoplasm of thyroid gland
0.845 0.155 0.000
M79.16 Myalgia (Lower leg)
0.845 0.155 0.000
T17.9 Foreign body in respiratory tract, part unspecified
0.845 0.155 0.000
T51 Toxic effect of alcohol
0.845 0.155 0.000
G96 Other disorders of central nervous system
0.843 0.157 0.000
T43.6 Psychostimulants with abuse potential
0.843 0.157 0.000
L60 Nail disorders
0.842 0.158 0.000
W29.9 Unspecified place
0.842 0.158 0.000
N27.0 Small kidney, unilateral
0.842 0.158 0.000
T45.5 Anticoagulants
0.842 0.158 0.000
Q83 Congenital malformations of breast
0.842 0.158 0.000
T00 Superficial injuries involving multiple body regions
0.841 0.159 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.841 0.159 0.000
G72 Other myopathies
0.841 0.159 0.000
T98 Sequelae of other and unspecified effects of external causes
0.841 0.159 0.000
A65-A69 Other spirochaetal diseases
0.841 0.159 0.000
C49.0 Connective and soft tissue of head, face and neck
0.840 0.159 0.000
H60.4 Cholesteatoma of external ear
0.840 0.160 0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.839 0.161 0.000
M34.8 Other forms of systemic sclerosis
0.839 0.161 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.838 0.162 0.000
S92.70 Multiple fractures of foot (closed)
0.838 0.162 0.000
G03 Meningitis due to other and unspecified causes
0.837 0.163 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.835 0.165 0.000
S31.0 Open wound of lower back and pelvis
0.835 0.165 0.000
W75-W84 Other accidental threats to breathing
0.835 0.165 0.000
M77.9 Enthesopathy, unspecified
0.835 0.165 0.000
W05 Fall involving wheelchair
0.835 0.165 0.000
C45.9 Mesothelioma, unspecified
0.831 0.169 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.831 0.169 0.000
F30.0 Hypomania
0.830 0.170 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.830 0.170 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.830 0.170 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.830 0.170 0.000
M89.38 Hypertrophy of bone (Other)
0.830 0.170 0.000
J85 Abscess of lung and mediastinum
0.829 0.171 0.000
M10.9 Gout, unspecified
0.829 0.171 0.000
V48 Car occupant injured in noncollision transport accident
0.829 0.171 0.000
G56 Mononeuropathies of upper limb
0.829 0.171 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.828 0.172 0.000
E34 Other endocrine disorders
0.828 0.172 0.000
J80 Adult respiratory distress syndrome
0.828 0.172 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.828 0.172 0.000
M89.37 Hypertrophy of bone (Ankle and foot)
0.827 0.173 0.000
C81.1 Nodular sclerosis
0.827 0.173 0.000
S92.50 Fracture of other toe (closed)
0.826 0.174 0.000
L23 Allergic contact dermatitis
0.826 0.174 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.826 0.174 0.000
V01-V09 Pedestrian injured in transport accident
0.826 0.174 0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot
0.825 0.175 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.825 0.175 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.825 0.175 0.000
Q87.4 Marfan's syndrome
0.824 0.176 0.000
C95 Leukaemia of unspecified cell type
0.824 0.176 0.000
S21 Open wound of thorax
0.824 0.176 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.823 0.177 0.000
G57.8 Other mononeuropathies of lower limb
0.823 0.177 0.000
T62 Toxic effect of other noxious substances eaten as food
0.822 0.178 0.000
E61.2 Magnesium deficiency
0.822 0.178 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.822 0.178 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.822 0.178 0.000
M89.07 Algoneurodystrophy (Ankle and foot)
0.821 0.178 0.000
X50-X57 Overexertion, travel and privation
0.821 0.179 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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