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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

Affx-21291542
log Bayes Factor = 12.1623
Chromosome 3   position 141,344,672  (GRCh37) Explore Affx-21291542 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
M05-M14 Inflammatory polyarthropathies
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.990 0.010 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.990 0.010 0.000
G81 Hemiplegia
0.986 0.014 0.000
Chapter II Neoplasms
0.984 0.016 0.000
G81.9 Hemiplegia, unspecified
0.983 0.017 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.980 0.020 0.000
I69 Sequelae of cerebrovascular disease
0.979 0.021 0.000
M45-M49 Spondylopathies
0.971 0.029 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.971 0.029 0.000
Chapter XX External causes of morbidity and mortality
0.967 0.033 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.965 0.035 0.000
Chapter X Diseases of the respiratory system
0.963 0.037 0.000
C15-C26 Malignant neoplasms of digestive organs
0.963 0.037 0.000
M10 Gout
0.961 0.039 0.000
Chapter VIII Diseases of the ear and mastoid process
0.959 0.041 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.958 0.042 0.000
J90-J94 Other diseases of pleura
0.947 0.053 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.946 0.054 0.000
M47 Spondylosis
0.945 0.055 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.944 0.056 0.000
M10.9 Gout, unspecified
0.937 0.063 0.000
E70-E90 Metabolic disorders
0.934 0.066 0.000
M13 Other arthritis
0.932 0.068 0.000
A30-A49 Other bacterial diseases
0.930 0.070 0.000
I05-I09 Chronic rheumatic heart diseases
0.929 0.071 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.928 0.072 0.000
L20-L30 Dermatitis and eczema
0.925 0.075 0.000
G40-G47 Episodic and paroxysmal disorders
0.923 0.077 0.000
C18 Malignant neoplasm of colon
0.923 0.077 0.000
E86 Volume depletion
0.921 0.079 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.919 0.081 0.000
C79 Secondary malignant neoplasm of other sites
0.916 0.084 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.915 0.085 0.000
M47.8 Other spondylosis
0.914 0.086 0.000
H90-H95 Other disorders of ear
0.902 0.098 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.901 0.099 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.895 0.105 0.000
M47.86 Other spondylosis (Lumbar region)
0.893 0.107 0.000
A49 Bacterial infection of unspecified site
0.890 0.110 0.000
D00-D09 In situ neoplasms
0.887 0.113 0.000
C15 Malignant neoplasm of oesophagus
0.883 0.117 0.000
M10.99 Gout, unspecified (Site unspecified)
0.882 0.118 0.000
J93 Pneumothorax
0.882 0.118 0.000
B95-B98 Bacterial, viral and other infectious agents
0.882 0.118 0.000
L60-L75 Disorders of skin appendages
0.881 0.119 0.000
I60 Subarachnoid haemorrhage
0.881 0.119 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.879 0.121 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.879 0.121 0.000
M13.9 Arthritis, unspecified
0.877 0.123 0.000
I27 Other pulmonary heart diseases
0.874 0.126 0.000
L27 Dermatitis due to substances taken internally
0.873 0.127 0.000
M80-M85 Disorders of bone density and structure
0.869 0.131 0.000
H65-H75 Diseases of middle ear and mastoid
0.864 0.136 0.000
H91 Other hearing loss
0.861 0.139 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.858 0.142 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.855 0.144 0.000
G47 Sleep disorders
0.852 0.148 0.000
G90-G99 Other disorders of the nervous system
0.852 0.148 0.000
L08 Other local infections of skin and subcutaneous tissue
0.851 0.149 0.000
J95-J99 Other diseases of the respiratory system
0.850 0.150 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.850 0.150 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.842 0.158 0.000
J93.9 Pneumothorax, unspecified
0.840 0.160 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.840 0.160 0.000
Y43 Primarily systemic agents
0.838 0.161 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.836 0.164 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.835 0.165 0.000
J92 Pleural plaque
0.834 0.166 0.000
H91.9 Hearing loss, unspecified
0.832 0.168 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.831 0.169 0.000
I62 Other nontraumatic intracranial haemorrhage
0.831 0.169 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.830 0.170 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.824 0.176 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.823 0.177 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.822 0.178 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.822 0.178 0.000
Y52 Agents primarily affecting the cardiovascular system
0.820 0.180 0.000
O85-O92 Complications predominantly related to the puerperium
0.820 0.180 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.820 0.180 0.000
A49.0 Staphylococcal infection, unspecified
0.817 0.183 0.000
I05 Rheumatic mitral valve diseases
0.817 0.183 0.000
I27.2 Other secondary pulmonary hypertension
0.812 0.188 0.000
M70-M79 Other soft tissue disorders
0.810 0.190 0.000
C21 Malignant neoplasm of anus and anal canal
0.809 0.191 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.807 0.193 0.000
Y57 Other and unspecified drugs and medicaments
0.805 0.195 0.000
M50-M54 Other dorsopathies
0.805 0.195 0.000
C34 Malignant neoplasm of bronchus and lung
0.804 0.196 0.000
B25-B34 Other viral diseases
0.803 0.197 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.802 0.198 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.799 0.201 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.799 0.201 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.798 0.202 0.000
G82 Paraplegia and tetraplegia
0.796 0.204 0.000
M40-M43 Deforming dorsopathies
0.796 0.204 0.000
J91 Pleural effusion in conditions classified elsewhere
0.796 0.204 0.000
C18.5 Splenic flexure
0.795 0.205 0.000
X60-X84 Intentional self-harm
0.793 0.207 0.000
I20-I25 Ischaemic heart diseases
0.790 0.210 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.790 0.210 0.000
W00-W19 Falls
0.790 0.210 0.000
Q60-Q64 Congenital malformations of the urinary system
0.789 0.210 0.000
M13.98 Arthritis, unspecified (Other)
0.789 0.211 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.788 0.211 0.000
M45 Ankylosing spondylitis
0.788 0.212 0.000
C18.6 Descending colon
0.787 0.213 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.785 0.215 0.000
M06 Other rheumatoid arthritis
0.784 0.216 0.000
C16 Malignant neoplasm of stomach
0.784 0.216 0.000
M86-M90 Other osteopathies
0.784 0.216 0.000
I08 Multiple valve diseases
0.784 0.216 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.783 0.217 0.000
Q50-Q56 Congenital malformations of genital organs
0.782 0.218 0.000
E20-E35 Disorders of other endocrine glands
0.781 0.219 0.000
L60 Nail disorders
0.779 0.221 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.779 0.221 0.000
M47.9 Spondylosis, unspecified
0.779 0.221 0.000
M20-M25 Other joint disorders
0.778 0.222 0.000
B35-B49 Mycoses
0.776 0.224 0.000
I69.3 Sequelae of cerebral infarction
0.774 0.226 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.772 0.228 0.000
C15.9 Oesophagus, unspecified
0.770 0.230 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.770 0.230 0.000
D06 Carcinoma in situ of cervix uteri
0.768 0.232 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.766 0.234 0.000
I27.0 Primary pulmonary hypertension
0.764 0.236 0.000
M91-M94 Chondropathies
0.764 0.236 0.000
M05 Seropositive rheumatoid arthritis
0.764 0.236 0.000
M00-M03 Infectious arthropathies
0.762 0.238 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.761 0.239 0.000
Y40 Systemic antibiotics
0.760 0.240 0.000
H65 Nonsuppurative otitis media
0.758 0.242 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.758 0.242 0.000
E87.6 Hypokalaemia
0.756 0.244 0.000
I67 Other cerebrovascular diseases
0.755 0.245 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.754 0.246 0.000
J92.9 Pleural plaque without asbestos
0.754 0.246 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.753 0.247 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.752 0.248 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.752 0.248 0.000
J90 Pleural effusion, not elsewhere classified
0.751 0.249 0.000
A49.8 Other bacterial infections of unspecified site
0.751 0.249 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.750 0.250 0.000
G47.9 Sleep disorder, unspecified
0.749 0.251 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.749 0.251 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.749 0.251 0.000
J30-J39 Other diseases of upper respiratory tract
0.747 0.253 0.000
Y43.3 Other antineoplastic drugs
0.746 0.254 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.746 0.254 0.000
G91 Hydrocephalus
0.744 0.256 0.000
Chapter XXII Codes for special purposes
0.744 0.256 0.000
C18.9 Colon, unspecified
0.744 0.256 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.743 0.257 0.000
L28 Lichen simplex chronicus and prurigo
0.740 0.259 0.000
O80-O84 Delivery
0.740 0.260 0.000
M60-M63 Disorders of muscles
0.740 0.260 0.000
C77.1 Intrathoracic lymph nodes
0.739 0.261 0.000
M07 Psoriatic and enteropathic arthropathies
0.738 0.262 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.738 0.262 0.000
E73 Lactose intolerance
0.737 0.263 0.000
M80 Osteoporosis with pathological fracture
0.737 0.263 0.000
H93 Other disorders of ear, not elsewhere classified
0.737 0.263 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.734 0.266 0.000
B15-B19 Viral hepatitis
0.733 0.267 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.733 0.267 0.000
Q21 Congenital malformations of cardiac septa
0.732 0.268 0.000
Chapter V Mental and behavioural disorders
0.732 0.268 0.000
C18.4 Transverse colon
0.731 0.269 0.000
S50-S59 Injuries to the elbow and forearm
0.730 0.270 0.000
I08.0 Disorders of both mitral and aortic valves
0.729 0.271 0.000
G70-G73 Diseases of myoneural junction and muscle
0.728 0.272 0.000
M10.96 Gout, unspecified (Lower leg)
0.726 0.274 0.000
M13.0 Polyarthritis, unspecified
0.724 0.276 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.724 0.276 0.000
Y44 Agents primarily affecting blood constituents
0.723 0.277 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.722 0.278 0.000
C18.7 Sigmoid colon
0.722 0.278 0.000
C18.0 Caecum
0.720 0.280 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.720 0.280 0.000
O00-O08 Pregnancy with abortive outcome
0.720 0.280 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.720 0.280 0.000
W50-W64 Exposure to animate mechanical forces
0.720 0.280 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.719 0.281 0.000
L60.0 Ingrowing nail
0.718 0.282 0.000
M46 Other inflammatory spondylopathies
0.718 0.282 0.000
C15.4 Middle third of oesophagus
0.718 0.282 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I05.2 Mitral stenosis with insufficiency
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.717 0.283 0.000
I07 Rheumatic tricuspid valve diseases
0.716 0.284 0.000
Q00-Q07 Congenital malformations of the nervous system
0.716 0.284 0.000
M24 Other specific joint derangements
0.716 0.284 0.000
I61 Intracerebral haemorrhage
0.716 0.284 0.000
D05 Carcinoma in situ of breast
0.716 0.284 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.715 0.285 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.715 0.285 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.714 0.286 0.000
G80 Infantile cerebral palsy
0.714 0.286 0.000
L73 Other follicular disorders
0.713 0.287 0.000
M14 Arthropathies in other diseases classified elsewhere
0.712 0.288 0.000
M12 Other specific arthropathies
0.712 0.288 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.712 0.288 0.000
M08 Juvenile arthritis
0.712 0.288 0.000
M47.82 Other spondylosis (Cervical region)
0.712 0.288 0.000
B99-B99 Other infectious diseases
0.710 0.290 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.710 0.290 0.000
B65-B83 Helminthiases
0.710 0.290 0.000
B50-B64 Protozoal diseases
0.710 0.290 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.710 0.290 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.710 0.290 0.000
A75-A79 Rickettsioses
0.710 0.290 0.000
A70-A74 Other diseases caused by chlamydiae
0.710 0.290 0.000
A65-A69 Other spirochaetal diseases
0.710 0.290 0.000
A20-A28 Certain zoonotic bacterial diseases
0.710 0.290 0.000
A15-A19 Tuberculosis
0.710 0.290 0.000
I21 Acute myocardial infarction
0.710 0.290 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.710 0.290 0.000
G45.4 Transient global amnesia
0.709 0.291 0.000
L50-L54 Urticaria and erythema
0.707 0.293 0.000
V10-V19 Pedal cyclist injured in transport accident
0.707 0.293 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.707 0.293 0.000
G81.1 Spastic hemiplegia
0.707 0.293 0.000
G81.0 Flaccid hemiplegia
0.707 0.293 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.706 0.294 0.000
M50 Cervical disk disorders
0.706 0.294 0.000
C77.2 Intra-abdominal lymph nodes
0.704 0.296 0.000
G47.3 Sleep apnoea
0.704 0.296 0.000
A49.1 Streptococcal infection, unspecified
0.703 0.297 0.000
B91 Sequelae of poliomyelitis
0.703 0.297 0.000
L10-L14 Bullous disorders
0.703 0.297 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.702 0.298 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.702 0.298 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.702 0.298 0.000
Chapter XIV Diseases of the genitourinary system
0.702 0.298 0.000
J80 Adult respiratory distress syndrome
0.700 0.300 0.000
C21.1 Anal canal
0.699 0.301 0.000
M49 Spondylopathies in diseases classified elsewhere
0.696 0.304 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.696 0.304 0.000
Q80-Q89 Other congenital malformations
0.696 0.304 0.000
Q35-Q37 Cleft lip and cleft palate
0.696 0.304 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.696 0.304 0.000
A00-A09 Intestinal infectious diseases
0.696 0.304 0.000
M84 Disorders of continuity of bone
0.695 0.305 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.693 0.307 0.000
Y35-Y36 Legal intervention and operations of war
0.693 0.307 0.000
Y10-Y34 Event of undetermined intent
0.693 0.307 0.000
Y00-Y09 Assault
0.693 0.307 0.000
X85-X99 Assault
0.693 0.307 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.693 0.307 0.000
X50-X57 Overexertion, travel and privation
0.693 0.307 0.000
X30-X39 Exposure to forces of nature
0.693 0.307 0.000
X20-X29 Contact with venomous animals and plants
0.693 0.307 0.000
X10-X19 Contact with heat and hot substances
0.693 0.307 0.000
X00-X09 Exposure to smoke, fire and flames
0.693 0.307 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.693 0.307 0.000
W75-W84 Other accidental threats to breathing
0.693 0.307 0.000
W65-W74 Accidental drowning and submersion
0.693 0.307 0.000
V98-V99 Other and unspecified transport accidents
0.693 0.307 0.000
V95-V97 Air and space transport accidents
0.693 0.307 0.000
V90-V94 Water transport accidents
0.693 0.307 0.000
V70-V79 Bus occupant injured in transport accident
0.693 0.307 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.693 0.307 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.693 0.307 0.000
V40-V49 Car occupant injured in transport accident
0.693 0.307 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.693 0.307 0.000
V20-V29 Motorcycle rider injured in transport accident
0.693 0.307 0.000
V01-V09 Pedestrian injured in transport accident
0.693 0.307 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.693 0.307 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.693 0.307 0.000
J98 Other respiratory disorders
0.693 0.307 0.000
Q18 Other congenital malformations of face and neck
0.692 0.308 0.000
C77.4 Inguinal and lower limb lymph nodes
0.691 0.308 0.000
G83 Other paralytic syndromes
0.691 0.309 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.691 0.309 0.000
C17 Malignant neoplasm of small intestine
0.691 0.309 0.000
C23 Malignant neoplasm of gallbladder
0.691 0.309 0.000
C79.6 Secondary malignant neoplasm of ovary
0.690 0.310 0.000
L05 Pilonidal cyst
0.690 0.310 0.000
E50-E64 Other nutritional deficiencies
0.689 0.311 0.000
M10.4 Other secondary gout
0.689 0.311 0.000
M10.3 Gout due to impairment of renal function
0.689 0.311 0.000
M10.2 Drug-induced gout
0.689 0.311 0.000
M10.1 Lead-induced gout
0.689 0.311 0.000
M10.0 Idiopathic gout
0.689 0.311 0.000
C15.5 Lower third of oesophagus
0.688 0.311 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.688 0.312 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.686 0.313 0.000
M47.2 Other spondylosis with radiculopathy
0.684 0.316 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.684 0.316 0.000
H74 Other disorders of middle ear and mastoid
0.684 0.316 0.000
C34.3 Lower lobe, bronchus or lung
0.683 0.317 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.683 0.317 0.000
O86 Other puerperal infections
0.682 0.318 0.000
D06.9 Cervix, unspecified
0.682 0.318 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.682 0.318 0.000
M65-M68 Disorders of synovium and tendon
0.682 0.318 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.682 0.318 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.681 0.319 0.000
S52 Fracture of forearm
0.680 0.320 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.680 0.320 0.000
V80-V89 Other land transport accidents
0.680 0.320 0.000
A80-A89 Viral infections of the central nervous system
0.679 0.321 0.000
Y59 Other and unspecified vaccines and biological substances
0.678 0.322 0.000
Y58 Bacterial vaccines
0.678 0.322 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.678 0.322 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.678 0.322 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.678 0.322 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.678 0.322 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.678 0.322 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.678 0.322 0.000
Y48 Anaesthetics and therapeutic gases
0.678 0.322 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.678 0.322 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.678 0.322 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.678 0.322 0.000
I67.1 Cerebral aneurysm, nonruptured
0.678 0.322 0.000
H66 Suppurative and unspecified otitis media
0.678 0.322 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.678 0.322 0.000
M47.1 Other spondylosis with myelopathy
0.677 0.322 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.677 0.322 0.000
C16.0 Cardia
0.678 0.322 0.000
W20-W49 Exposure to inanimate mechanical forces
0.676 0.324 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.676 0.324 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.675 0.324 0.000
H90 Conductive and sensorineural hearing loss
0.675 0.325 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.674 0.326 0.000
Y57.9 Drug or medicament, unspecified
0.674 0.326 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.673 0.327 0.000
G43 Migraine
0.673 0.327 0.000
D04 Carcinoma in situ of skin
0.673 0.327 0.000
C78.0 Secondary malignant neoplasm of lung
0.673 0.327 0.000
M10.98 Gout, unspecified (Other)
0.672 0.328 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.672 0.328 0.000
M10.94 Gout, unspecified (Hand)
0.672 0.328 0.000
M10.93 Gout, unspecified (Forearm)
0.672 0.328 0.000
M10.92 Gout, unspecified (Upper arm)
0.672 0.328 0.000
M10.91 Gout, unspecified (Shoulder region)
0.672 0.328 0.000
M10.90 Gout, unspecified (Multiple sites)
0.672 0.328 0.000
G41 Status epilepticus
0.671 0.329 0.000
G44 Other headache syndromes
0.670 0.329 0.000
I10-I15 Hypertensive diseases
0.670 0.330 0.000
E88 Other metabolic disorders
0.670 0.330 0.000
H65.3 Chronic mucoid otitis media
0.670 0.330 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.669 0.330 0.000
E85 Amyloidosis
0.669 0.331 0.000
E84 Cystic fibrosis
0.669 0.331 0.000
E79 Disorders of purine and pyrimidine metabolism
0.669 0.331 0.000
E77 Disorders of glycoprotein metabolism
0.669 0.331 0.000
E76 Disorders of glycosaminoglycan metabolism
0.669 0.331 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.669 0.331 0.000
E74 Other disorders of carbohydrate metabolism
0.669 0.331 0.000
E72 Other disorders of amino-acid metabolism
0.669 0.331 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.669 0.331 0.000
E70 Disorders of aromatic amino-acid metabolism
0.669 0.331 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.669 0.331 0.000
G47.8 Other sleep disorders
0.669 0.331 0.000
M13.8 Other specified arthritis
0.668 0.332 0.000
M13.1 Monoarthritis, not elsewhere classified
0.668 0.332 0.000
D03 Melanoma in situ
0.668 0.332 0.000
G91.9 Hydrocephalus, unspecified
0.668 0.332 0.000
O16 Unspecified maternal hypertension
0.667 0.333 0.000
A48 Other bacterial diseases, not elsewhere classified
0.667 0.333 0.000
A44 Bartonellosis
0.667 0.333 0.000
A43 Nocardiosis
0.667 0.333 0.000
A42 Actinomycosis
0.667 0.333 0.000
A40 Streptococcal septicaemia
0.667 0.333 0.000
A39 Meningococcal infection
0.667 0.333 0.000
A37 Whooping cough
0.667 0.333 0.000
A36 Diphtheria
0.667 0.333 0.000
A32 Listeriosis
0.667 0.333 0.000
A31 Infection due to other mycobacteria
0.667 0.333 0.000
A30 Leprosy [Hansen's disease]
0.667 0.333 0.000
A46 Erysipelas
0.667 0.333 0.000
A38 Scarlet fever
0.667 0.333 0.000
A35 Other tetanus
0.667 0.333 0.000
A34 Obstetrical tetanus
0.667 0.333 0.000
A33 Tetanus neonatorum
0.667 0.333 0.000
I09 Other rheumatic heart diseases
0.666 0.334 0.000
I06 Rheumatic aortic valve diseases
0.666 0.334 0.000
L29 Pruritus
0.666 0.334 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.665 0.335 0.000
L25 Unspecified contact dermatitis
0.663 0.337 0.000
L24 Irritant contact dermatitis
0.663 0.337 0.000
L23 Allergic contact dermatitis
0.663 0.337 0.000
L21 Seborrhoeic dermatitis
0.663 0.337 0.000
L20 Atopic dermatitis
0.663 0.337 0.000
L26 Exfoliative dermatitis
0.663 0.337 0.000
L22 Diaper [napkin] dermatitis
0.663 0.337 0.000
C34.1 Upper lobe, bronchus or lung
0.663 0.337 0.000
M50.1 Cervical disk disorder with radiculopathy
0.663 0.337 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.662 0.338 0.000
C18.8 Overlapping lesion of colon
0.661 0.338 0.000
C18.1 Appendix
0.661 0.338 0.000
N25-N29 Other disorders of kidney and ureter
0.660 0.340 0.000
D80-D89 Certain disorders involving the immune mechanism
0.660 0.340 0.000
G90 Disorders of autonomic nervous system
0.660 0.340 0.000
C04 Malignant neoplasm of floor of mouth
0.658 0.342 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.657 0.343 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.657 0.343 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.657 0.343 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.657 0.343 0.000
H72 Perforation of tympanic membrane
0.656 0.343 0.000
I28 Other diseases of pulmonary vessels
0.656 0.344 0.000
J94 Other pleural conditions
0.656 0.344 0.000
M11 Other crystal arthropathies
0.655 0.344 0.000
M47.89 Other spondylosis (Site unspecified)
0.655 0.345 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.655 0.345 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.655 0.345 0.000
M47.84 Other spondylosis (Thoracic region)
0.655 0.345 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.655 0.345 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.655 0.345 0.000
J98.4 Other disorders of lung
0.655 0.345 0.000
G93 Other disorders of brain
0.655 0.345 0.000
M79.8 Other specified soft tissue disorders
0.655 0.345 0.000
J60-J70 Lung diseases due to external agents
0.655 0.345 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.654 0.346 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.653 0.347 0.000
O60-O75 Complications of labour and delivery
0.653 0.347 0.000
A41 Other septicaemia
0.653 0.347 0.000
M85 Other disorders of bone density and structure
0.653 0.347 0.000
Q27 Other congenital malformations of peripheral vascular system
0.652 0.347 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.651 0.349 0.000
E40-E46 Malnutrition
0.650 0.350 0.000
M13.93 Arthritis, unspecified (Forearm)
0.650 0.350 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.650 0.350 0.000
C34.9 Bronchus or lung, unspecified
0.649 0.351 0.000
B44 Aspergillosis
0.649 0.351 0.000
Y45.1 Salicylates
0.648 0.352 0.000
Q21.1 Atrial septal defect
0.648 0.352 0.000
S52.5 Fracture of lower end of radius
0.648 0.352 0.000
C09 Malignant neoplasm of tonsil
0.647 0.353 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.647 0.353 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.647 0.353 0.000
B25 Cytomegaloviral disease
0.646 0.353 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.646 0.354 0.000
O97 Death from sequelae of direct obstetric causes
0.646 0.354 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.646 0.354 0.000
O95 Obstetric death of unspecified cause
0.646 0.354 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.646 0.354 0.000
M79.7 Fibromyalgia
0.646 0.354 0.000
F41 Other anxiety disorders
0.645 0.355 0.000
O90 Complications of the puerperium, not elsewhere classified
0.645 0.355 0.000
C77.0 Lymph nodes of head, face and neck
0.645 0.355 0.000
H69 Other disorders of Eustachian tube
0.645 0.355 0.000
L30 Other dermatitis
0.644 0.356 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.643 0.357 0.000
M13.94 Arthritis, unspecified (Hand)
0.642 0.358 0.000
L04 Acute lymphadenitis
0.642 0.358 0.000
L01 Impetigo
0.642 0.358 0.000
L00 Staphylococcal scalded skin syndrome
0.642 0.358 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.641 0.358 0.000
A49.9 Bacterial infection, unspecified
0.641 0.359 0.000
Y43.4 Immunosuppressive agents
0.641 0.359 0.000
S40-S49 Injuries to the shoulder and upper arm
0.641 0.359 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.640 0.360 0.000
J09-J18 Influenza and pneumonia
0.640 0.360 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.640 0.360 0.000
I21.9 Acute myocardial infarction, unspecified
0.640 0.360 0.000
D60-D64 Aplastic and other anaemias
0.639 0.360 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.639 0.361 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.639 0.361 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.638 0.362 0.000
A49.3 Mycoplasma infection, unspecified
0.638 0.362 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.638 0.362 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.638 0.362 0.000
I30-I52 Other forms of heart disease
0.637 0.363 0.000
N17-N19 Renal failure
0.637 0.363 0.000
C64-C68 Malignant neoplasms of urinary tract
0.637 0.363 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.636 0.364 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.636 0.364 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.636 0.364 0.000
C01 Malignant neoplasm of base of tongue
0.636 0.364 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.635 0.365 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.635 0.365 0.000
L40-L45 Papulosquamous disorders
0.635 0.365 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.634 0.366 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.633 0.367 0.000
C78.2 Secondary malignant neoplasm of pleura
0.633 0.367 0.000
J38.3 Other diseases of vocal cords
0.633 0.367 0.000
C15.8 Overlapping lesion of oesophagus
0.633 0.367 0.000
C15.3 Upper third of oesophagus
0.633 0.367 0.000
C15.2 Abdominal part of oesophagus
0.633 0.367 0.000
C15.1 Thoracic part of oesophagus
0.633 0.367 0.000
C15.0 Cervical part of oesophagus
0.633 0.367 0.000
J93.8 Other pneumothorax
0.633 0.367 0.000
J93.0 Spontaneous tension pneumothorax
0.633 0.367 0.000
Q61 Cystic kidney disease
0.633 0.367 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.632 0.368 0.000
Q28 Other congenital malformations of circulatory system
0.632 0.368 0.000
S90-S99 Injuries to the ankle and foot
0.632 0.368 0.000
L75 Apocrine sweat disorders
0.632 0.368 0.000
L74 Eccrine sweat disorders
0.632 0.368 0.000
L70 Acne
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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