TreeWAS – Variant ID: rs10046456

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter VI Diseases of the nervous system	0.994	0.006
E20-E35 Disorders of other endocrine glands	0.991	0.009
M80-M85 Disorders of bone density and structure	0.983	0.017
M45-M49 Spondylopathies	0.965	0.035
M50-M54 Other dorsopathies	0.963	0.037
S00-S09 Injuries to the head	0.954	0.046
M80 Osteoporosis with pathological fracture	0.948	0.052
Chapter XX External causes of morbidity and mortality	0.945	0.055
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.937	0.063
E70-E90 Metabolic disorders	0.937	0.063
S01 Open wound of head	0.937	0.063
Chapter I Certain infectious and parasitic diseases	0.935	0.065
E87 Other disorders of fluid, electrolyte and acid-base balance	0.934	0.066
G35-G37 Demyelinating diseases of the central nervous system	0.933	0.067
E27 Other disorders of adrenal gland	0.930	0.070
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.928	0.071
S70-S79 Injuries to the hip and thigh	0.921	0.079
M86-M90 Other osteopathies	0.919	0.081
E87.2 Acidosis	0.919	0.081
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.916	0.084
B35-B49 Mycoses	0.912	0.088
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.909	0.091
M84 Disorders of continuity of bone	0.907	0.093
E87.1 Hypo-osmolality and hyponatraemia	0.899	0.101
M80.9 Unspecified osteoporosis with pathological fracture	0.899	0.101
M65-M68 Disorders of synovium and tendon	0.898	0.102
G80-G83 Cerebral palsy and other paralytic syndromes	0.896	0.104
E28 Ovarian dysfunction	0.895	0.105
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.895	0.105
G00-G09 Inflammatory diseases of the central nervous system	0.888	0.112
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.884	0.116
E27.1 Primary adrenocortical insufficiency	0.882	0.118
M45 Ankylosing spondylitis	0.880	0.120
E16 Other disorders of pancreatic internal secretion	0.878	0.122
E10-E14 Diabetes mellitus	0.876	0.124
E50-E64 Other nutritional deficiencies	0.873	0.127
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.866	0.134
M50 Cervical disk disorders	0.864	0.136
G70-G73 Diseases of myoneural junction and muscle	0.860	0.140
M05-M14 Inflammatory polyarthropathies	0.858	0.142
S10-S19 Injuries to the neck	0.857	0.143
M40-M43 Deforming dorsopathies	0.856	0.144
D69 Purpura and other haemorrhagic conditions	0.853	0.147
W20-W49 Exposure to inanimate mechanical forces	0.845	0.155
E10 Insulin-dependent diabetes mellitus	0.844	0.156
E22 Hyperfunction of pituitary gland	0.843	0.157
E16.2 Hypoglycaemia, unspecified	0.841	0.159
M47 Spondylosis	0.840	0.160
T51 Toxic effect of alcohol	0.835	0.165
W00-W19 Falls	0.834	0.166
G37 Other demyelinating diseases of central nervous system	0.834	0.166
Chapter XV Pregnancy, childbirth and the puerperium	0.833	0.167
E28.2 Polycystic ovarian syndrome	0.827	0.173
B37 Candidiasis	0.826	0.174
S40-S49 Injuries to the shoulder and upper arm	0.825	0.175
X40-X49 Accidental poisoning by and exposure to noxious substances	0.822	0.178
S60-S69 Injuries to the wrist and hand	0.822	0.178
A80-A89 Viral infections of the central nervous system	0.821	0.179
S01.2 Open wound of nose	0.818	0.182
S01.8 Open wound of other parts of head	0.817	0.183
M67 Other disorders of synovium and tendon	0.817	0.183
G35 Multiple sclerosis	0.816	0.184
T20-T25 Burns and corrosions of external body surface, specified by site	0.816	0.184
M53 Other dorsopathies, not elsewhere classified	0.815	0.185
T15-T19 Effects of foreign body entering through natural orifice	0.812	0.188
E29 Testicular dysfunction	0.810	0.190
G83 Other paralytic syndromes	0.810	0.190
Chapter X Diseases of the respiratory system	0.808	0.192
S01.7 Multiple open wounds of head	0.805	0.195
S01.4 Open wound of cheek and temporomandibular area	0.805	0.195
M47.9 Spondylosis, unspecified	0.804	0.196
B15-B19 Viral hepatitis	0.804	0.196
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.802	0.198
T91 Sequelae of injuries of neck and trunk	0.802	0.198
M51 Other intervertebral disk disorders	0.799	0.201
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.799	0.201
G90-G99 Other disorders of the nervous system	0.798	0.202
D68 Other coagulation defects	0.797	0.203
M85 Other disorders of bone density and structure	0.796	0.204
Chapter V Mental and behavioural disorders	0.794	0.206
M46 Other inflammatory spondylopathies	0.793	0.207
S32 Fracture of lumbar spine and pelvis	0.789	0.211
W25 Contact with sharp glass	0.787	0.213
T58 Toxic effect of carbon monoxide	0.787	0.213
E23 Hypofunction and other disorders of pituitary gland	0.786	0.214
S05 Injury of eye and orbit	0.786	0.214
B44 Aspergillosis	0.785	0.215
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.784	0.216
T51.9 Alcohol, unspecified	0.782	0.218
M90 Osteopathies in diseases classified elsewhere	0.782	0.218
M84.0 Malunion of fracture	0.781	0.219
M91-M94 Chondropathies	0.780	0.220
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.779	0.221
M89 Other disorders of bone	0.778	0.222
G82 Paraplegia and tetraplegia	0.777	0.223
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.776	0.224
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.775	0.225
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.775	0.225
G20-G26 Extrapyramidal and movement disorders	0.774	0.226
T00-T07 Injuries involving multiple body regions	0.773	0.226
M50.2 Other cervical disk displacement	0.772	0.228
S01.5 Open wound of lip and oral cavity	0.772	0.228
S72 Fracture of femur	0.771	0.229
S20-S29 Injuries to the thorax	0.771	0.229
S06 Intracranial injury	0.770	0.230
M06 Other rheumatoid arthritis	0.767	0.233
M47.99 Spondylosis, unspecified (Site unspecified)	0.767	0.233
E87.7 Fluid overload	0.764	0.236
G50-G59 Nerve, nerve root and plexus disorders	0.764	0.236
M60-M63 Disorders of muscles	0.763	0.237
D69.6 Thrombocytopenia, unspecified	0.763	0.237
M50.3 Other cervical disk degeneration	0.760	0.240
M84.1 Nonunion of fracture [pseudarthrosis]	0.759	0.241
S69 Other and unspecified injuries of wrist and hand	0.758	0.242
O42 Premature rupture of membranes	0.756	0.243
B35 Dermatophytosis	0.755	0.245
J60-J70 Lung diseases due to external agents	0.755	0.245
Chapter XXII Codes for special purposes	0.754	0.246
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.753	0.247
T59 Toxic effect of other gases, fumes and vapours	0.752	0.248
W08 Fall involving other furniture	0.752	0.248
S41 Open wound of shoulder and upper arm	0.748	0.252
W25.9 Unspecified place	0.746	0.254
B49 Unspecified mycosis	0.746	0.254
X10-X19 Contact with heat and hot substances	0.745	0.254
B37.8 Candidiasis of other sites	0.745	0.255
E55 Vitamin D deficiency	0.744	0.256
S70 Superficial injury of hip and thigh	0.742	0.258
S01.3 Open wound of ear	0.741	0.259
G37.9 Demyelinating disease of central nervous system, unspecified	0.741	0.259
M54 Dorsalgia	0.740	0.260
W75-W84 Other accidental threats to breathing	0.739	0.260
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.736	0.264
F20 Schizophrenia	0.735	0.265
S76 Injury of muscle and tendon at hip and thigh level	0.734	0.266
V98-V99 Other and unspecified transport accidents	0.733	0.267
G72 Other myopathies	0.733	0.267
M45.X9 Ankylosing spondylitis (Site unspecified)	0.732	0.268
O42.9 Premature rupture of membranes, unspecified	0.730	0.270
X58-X59 Accidental exposure to other and unspecified factors	0.730	0.270
E24 Cushing's syndrome	0.729	0.271
E10.4 With neurological complications	0.724	0.276
E87.3 Alkalosis	0.722	0.278
E34 Other endocrine disorders	0.721	0.279
S79 Other and unspecified injuries of hip and thigh	0.721	0.279
S36 Injury of intra-abdominal organs	0.721	0.279
E26 Hyperaldosteronism	0.719	0.280
B65-B83 Helminthiases	0.719	0.281
E87.5 Hyperkalaemia	0.718	0.282
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
M06.9 Rheumatoid arthritis, unspecified	0.717	0.283
M20-M25 Other joint disorders	0.716	0.284
M67.8 Other specified disorders of synovium and tendon	0.715	0.285
S90-S99 Injuries to the ankle and foot	0.714	0.286
M84.4 Pathological fracture, not elsewhere classified	0.714	0.286
S69.9 Unspecified injury of wrist and hand	0.713	0.287
E10.9 Without complications	0.713	0.287
V40-V49 Car occupant injured in transport accident	0.712	0.288
E35 Disorders of endocrine glands in diseases classified elsewhere	0.710	0.290
E32 Diseases of thymus	0.710	0.290
E31 Polyglandular dysfunction	0.710	0.290
E30 Disorders of puberty, not elsewhere classified	0.710	0.290
E25 Adrenogenital disorders	0.710	0.290
E20 Hypoparathyroidism	0.710	0.290
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.708	0.291
M80.5 Idiopathic osteoporosis with pathological fracture	0.707	0.293
E85 Amyloidosis	0.707	0.293
W50-W64 Exposure to animate mechanical forces	0.706	0.294
M43 Other deforming dorsopathies	0.705	0.294
O44 Placenta praevia	0.705	0.295
A87 Viral meningitis	0.705	0.295
M83 Adult osteomalacia	0.705	0.295
D60-D64 Aplastic and other anaemias	0.705	0.295
D69.3 Idiopathic thrombocytopenic purpura	0.705	0.295
T92 Sequelae of injuries of upper limb	0.704	0.296
G83.1 Monoplegia of lower limb	0.704	0.296
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.704	0.296
E10.8 With unspecified complications	0.703	0.297
E22.1 Hyperprolactinaemia	0.702	0.298
Y00-Y09 Assault	0.701	0.299
E00-E07 Disorders of thyroid gland	0.701	0.299
M80.0 Postmenopausal osteoporosis with pathological fracture	0.700	0.300
S01.1 Open wound of eyelid and periocular area	0.698	0.302
E13 Other specified diabetes mellitus	0.698	0.302
E27.8 Other specified disorders of adrenal gland	0.698	0.302
T36-T50 Poisoning by drugs, medicaments and biological substances	0.696	0.304
E10.1 With ketoacidosis	0.695	0.305
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.695	0.305
G04 Encephalitis, myelitis and encephalomyelitis	0.695	0.305
T79-T79 Certain early complications of trauma	0.694	0.306
M24 Other specific joint derangements	0.694	0.306
E61 Deficiency of other nutrient elements	0.694	0.306
S30 Superficial injury of abdomen, lower back and pelvis	0.694	0.306
B15 Acute hepatitis A	0.694	0.306
W08.0 Home	0.692	0.308
S41.1 Open wound of upper arm	0.692	0.308
S19 Other and unspecified injuries of neck	0.692	0.308
M49 Spondylopathies in diseases classified elsewhere	0.691	0.308
M88 Paget's disease of bone [osteitis deformans]	0.691	0.309
E80 Disorders of porphyrin and bilirubin metabolism	0.690	0.310
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.690	0.310
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.689	0.311
M00-M03 Infectious arthropathies	0.689	0.311
M65 Synovitis and tenosynovitis	0.688	0.312
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.687	0.313
T90 Sequelae of injuries of head	0.686	0.314
X47 Accidental poisoning by and exposure to other gases and vapours	0.686	0.314
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.685	0.314
B90-B94 Sequelae of infectious and parasitic diseases	0.685	0.315
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.685	0.315
Q38-Q45 Other congenital malformations of the digestive system	0.684	0.316
S08 Traumatic amputation of part of head	0.684	0.316
S07 Crushing injury of head	0.684	0.316
S04 Injury of cranial nerves	0.684	0.316
S03 Dislocation, sprain and strain of joints and ligaments of head	0.684	0.316
M90.7 Fracture of bone in neoplastic disease	0.683	0.317
S62 Fracture at wrist and hand level	0.683	0.317
G03 Meningitis due to other and unspecified causes	0.683	0.317
E29.1 Testicular hypofunction	0.681	0.319
S72.2 Subtrochanteric fracture	0.681	0.319
G12 Spinal muscular atrophy and related syndromes	0.680	0.319
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.680	0.320
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.680	0.320
E40-E46 Malnutrition	0.680	0.320
M80.8 Other osteoporosis with pathological fracture	0.680	0.320
M80.4 Drug-induced osteoporosis with pathological fracture	0.680	0.320
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.680	0.320
M80.2 Osteoporosis of disuse with pathological fracture	0.680	0.320
E22.0 Acromegaly and pituitary gigantism	0.679	0.321
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.678	0.322
J69 Pneumonitis due to solids and liquids	0.678	0.322
Y35-Y36 Legal intervention and operations of war	0.678	0.322
Y10-Y34 Event of undetermined intent	0.678	0.322
X85-X99 Assault	0.678	0.322
X30-X39 Exposure to forces of nature	0.678	0.322
X00-X09 Exposure to smoke, fire and flames	0.678	0.322
W65-W74 Accidental drowning and submersion	0.678	0.322
V95-V97 Air and space transport accidents	0.678	0.322
V90-V94 Water transport accidents	0.678	0.322
V70-V79 Bus occupant injured in transport accident	0.678	0.322
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.678	0.322
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.678	0.322
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.678	0.322
V01-V09 Pedestrian injured in transport accident	0.678	0.322
E23.2 Diabetes insipidus	0.678	0.322
M48 Other spondylopathies	0.677	0.323
G83.4 Cauda equina syndrome	0.677	0.323
M47.92 Spondylosis, unspecified (Cervical region)	0.677	0.323
M82 Osteoporosis in diseases classified elsewhere	0.676	0.324
M86 Osteomyelitis	0.676	0.324
S50-S59 Injuries to the elbow and forearm	0.675	0.325
O85-O92 Complications predominantly related to the puerperium	0.675	0.325
M05 Seropositive rheumatoid arthritis	0.675	0.325
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.675	0.325
M87 Osteonecrosis	0.675	0.325
M40 Kyphosis and lordosis	0.674	0.326
M67.0 Short Achilles tendon (acquired)	0.672	0.328
O60-O75 Complications of labour and delivery	0.672	0.328
T65 Toxic effect of other and unspecified substances	0.672	0.328
T62 Toxic effect of other noxious substances eaten as food	0.672	0.328
T61 Toxic effect of noxious substances eaten as seafood	0.672	0.328
T60 Toxic effect of pesticides	0.672	0.328
T57 Toxic effect of other inorganic substances	0.672	0.328
T56 Toxic effect of metals	0.672	0.328
T54 Toxic effect of corrosive substances	0.672	0.328
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.672	0.328
T52 Toxic effect of organic solvents	0.672	0.328
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.672	0.328
T55 Toxic effect of soaps and detergents	0.672	0.328
E84 Cystic fibrosis	0.672	0.328
E79 Disorders of purine and pyrimidine metabolism	0.672	0.328
E77 Disorders of glycoprotein metabolism	0.672	0.328
E76 Disorders of glycosaminoglycan metabolism	0.672	0.328
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.672	0.328
E74 Other disorders of carbohydrate metabolism	0.672	0.328
E73 Lactose intolerance	0.672	0.328
E72 Other disorders of amino-acid metabolism	0.672	0.328
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.672	0.328
E70 Disorders of aromatic amino-acid metabolism	0.672	0.328
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.672	0.328
O34 Maternal care for known or suspected abnormality of pelvic organs	0.671	0.329
M46.9 Inflammatory spondylopathy, unspecified	0.670	0.329
B85-B89 Pediculosis, acariasis and other infestations	0.670	0.330
B50-B64 Protozoal diseases	0.670	0.330
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.670	0.330
A75-A79 Rickettsioses	0.670	0.330
A70-A74 Other diseases caused by chlamydiae	0.670	0.330
A65-A69 Other spirochaetal diseases	0.670	0.330
A20-A28 Certain zoonotic bacterial diseases	0.670	0.330
A15-A19 Tuberculosis	0.670	0.330
J30-J39 Other diseases of upper respiratory tract	0.670	0.330
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.670	0.330
E87.4 Mixed disorder of acid-base balance	0.670	0.330
M89.8 Other specified disorders of bone	0.669	0.330
T66-T78 Other and unspecified effects of external causes	0.669	0.331
G36 Other acute disseminated demyelination	0.669	0.331
G90 Disorders of autonomic nervous system	0.669	0.331
O40 Polyhydramnios	0.669	0.331
V20-V29 Motorcycle rider injured in transport accident	0.668	0.332
M10 Gout	0.668	0.332
E27.9 Disorder of adrenal gland, unspecified	0.667	0.333
E27.5 Adrenomedullary hyperfunction	0.667	0.333
E27.3 Drug-induced adrenocortical insufficiency	0.667	0.333
E27.2 Addisonian crisis	0.667	0.333
E27.0 Other adrenocortical overactivity	0.667	0.333
J95-J99 Other diseases of the respiratory system	0.667	0.333
G82.2 Paraplegia, unspecified	0.666	0.334
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.666	0.334
E15 Nondiabetic hypoglycaemic coma	0.666	0.334
D66 Hereditary factor VIII deficiency	0.665	0.334
T91.1 Sequelae of fracture of spine	0.665	0.335
B44.1 Other pulmonary aspergillosis	0.665	0.335
M54.1 Radiculopathy	0.665	0.335
D68.8 Other specified coagulation defects	0.665	0.335
D69.4 Other primary thrombocytopenia	0.664	0.336
E27.4 Other and unspecified adrenocortical insufficiency	0.664	0.336
M84.03 Malunion of fracture (Forearm)	0.664	0.336
S32.5 Fracture of pubis	0.663	0.337
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.663	0.337
S05.8 Other injuries of eye and orbit	0.663	0.337
B99-B99 Other infectious diseases	0.662	0.338
T18 Foreign body in alimentary tract	0.661	0.339
X20-X29 Contact with venomous animals and plants	0.661	0.339
E88 Other metabolic disorders	0.661	0.339
D68.9 Coagulation defect, unspecified	0.660	0.340
S78 Traumatic amputation of hip and thigh	0.660	0.340
S77 Crushing injury of hip and thigh	0.660	0.340
S75 Injury of blood vessels at hip and thigh level	0.660	0.340
S74 Injury of nerves at hip and thigh level	0.660	0.340
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.660	0.340
S71 Open wound of hip and thigh	0.660	0.340
F20.0 Paranoid schizophrenia	0.659	0.341
M85.8 Other specified disorders of bone density and structure	0.659	0.341
G70 Myasthenia gravis and other myoneural disorders	0.658	0.341
D69.9 Haemorrhagic condition, unspecified	0.658	0.342
T94 Sequelae of injuries involving multiple and unspecified body regions	0.658	0.342
T91.8 Sequelae of other specified injuries of neck and trunk	0.658	0.342
O43 Placental disorders	0.658	0.342
A86 Unspecified viral encephalitis	0.656	0.344
F20.9 Schizophrenia, unspecified	0.656	0.344
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.655	0.345
G30-G32 Other degenerative diseases of the nervous system	0.655	0.345
B48 Other mycoses, not elsewhere classified	0.654	0.346
B47 Mycetoma	0.654	0.346
B46 Zygomycosis	0.654	0.346
B45 Cryptococcosis	0.654	0.346
B43 Chromomycosis and phaeomycotic abscess	0.654	0.346
B42 Sporotrichosis	0.654	0.346
B41 Paracoccidioidomycosis	0.654	0.346
B40 Blastomycosis	0.654	0.346
B39 Histoplasmosis	0.654	0.346
B38 Coccidioidomycosis	0.654	0.346
B36 Other superficial mycoses	0.654	0.346
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.653	0.346
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.653	0.347
S09 Other and unspecified injuries of head	0.652	0.348
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.652	0.348
S37 Injury of urinary and pelvic organs	0.652	0.348
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.652	0.348
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.652	0.348
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.652	0.348
S31 Open wound of abdomen, lower back and pelvis	0.652	0.348
W14 Fall from tree	0.651	0.349
E55.9 Vitamin D deficiency, unspecified	0.651	0.349
S01.9 Open wound of head, part unspecified	0.651	0.349
M84.9 Disorder of continuity of bone, unspecified	0.650	0.350
M84.8 Other disorders of continuity of bone	0.650	0.350
M84.3 Stress fracture, not elsewhere classified	0.650	0.350
M84.2 Delayed union of fracture	0.650	0.350
B37.9 Candidiasis, unspecified	0.649	0.351
V80-V89 Other land transport accidents	0.648	0.351
A50-A64 Infections with a predominantly sexual mode of transmission	0.648	0.352
G98 Other disorders of nervous system, not elsewhere classified	0.648	0.352
G96 Other disorders of central nervous system	0.648	0.352
T63 Toxic effect of contact with venomous animals	0.647	0.353
W06 Fall involving bed	0.647	0.353
T91.3 Sequelae of injury of spinal cord	0.647	0.353
D69.0 Allergic purpura	0.647	0.353
M50.1 Cervical disk disorder with radiculopathy	0.646	0.354
D55-D59 Haemolytic anaemias	0.644	0.355
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.644	0.355
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.644	0.355
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.644	0.355
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.644	0.355
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.644	0.355
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.644	0.355
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.644	0.355
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.644	0.355
G94 Other disorders of brain in diseases classified elsewhere	0.644	0.356
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.643	0.356
E28.9 Ovarian dysfunction, unspecified	0.642	0.358
E28.8 Other ovarian dysfunction	0.642	0.358
E28.3 Primary ovarian failure	0.642	0.358
E28.1 Androgen excess	0.642	0.358
E28.0 Oestrogen excess	0.642	0.358
D67 Hereditary factor IX deficiency	0.642	0.358
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.642	0.358
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.642	0.358
S49 Other and unspecified injuries of shoulder and upper arm	0.642	0.358
B37.1 Pulmonary candidiasis	0.640	0.360
D68.6 Other Thrombophilia	0.640	0.360
M47.1 Other spondylosis with myelopathy	0.639	0.361
F29 Unspecified nonorganic psychosis	0.639	0.361
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.639	0.361
S46 Injury of muscle and tendon at shoulder and upper arm level	0.639	0.361
X50-X57 Overexertion, travel and privation	0.639	0.361
G71 Primary disorders of muscles	0.638	0.362
S12 Fracture of neck	0.638	0.362
B35.3 Tinea pedis	0.637	0.363
W13 Fall from, out of or through building or structure	0.637	0.363
G06 Intracranial and intraspinal abscess and granuloma	0.636	0.363
G00 Bacterial meningitis, not elsewhere classified	0.636	0.363
G09 Sequelae of inflammatory diseases of central nervous system	0.636	0.363
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.636	0.363
G01 Meningitis in bacterial diseases classified elsewhere	0.636	0.363
T20 Burn and corrosion of head and neck	0.636	0.364
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.635	0.365
M24.8 Other specific joint derangements, not elsewhere classified	0.634	0.366
E10.3 With ophthalmic complications	0.634	0.366
T95 Sequelae of burns, corrosions and frostbite	0.634	0.366
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.634	0.366
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.634	0.366
E53 Deficiency of other B group vitamins	0.633	0.367
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.632	0.368
M41 Scoliosis	0.632	0.368
S06.8 Other intracranial injuries	0.632	0.368
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.631	0.369
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.631	0.369
M45.X6 Ankylosing spondylitis (Lumbar region)	0.631	0.369
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.631	0.369
M45.X4 Ankylosing spondylitis (Thoracic region)	0.631	0.369
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.631	0.369
M45.X2 Ankylosing spondylitis (Cervical region)	0.631	0.369
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.631	0.369
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.631	0.369
G25 Other extrapyramidal and movement disorders	0.630	0.370
M51.9 Intervertebral disk disorder, unspecified	0.630	0.370
E16.9 Disorder of pancreatic internal secretion, unspecified	0.629	0.371
E16.8 Other specified disorders of pancreatic internal secretion	0.629	0.371
E16.4 Abnormal secretion of gastrin	0.629	0.371
E16.3 Increased secretion of glucagon	0.629	0.371
E16.1 Other hypoglycaemia	0.629	0.371
E16.0 Drug-induced hypoglycaemia without coma	0.629	0.371
G59 Mononeuropathy in diseases classified elsewhere	0.629	0.371
F22 Persistent delusional disorders	0.629	0.371
X60-X84 Intentional self-harm	0.628	0.372
E12 Malnutrition-related diabetes mellitus	0.628	0.372
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.626	0.374
E64 Sequelae of malnutrition and other nutritional deficiencies	0.626	0.374
E63 Other nutritional deficiencies	0.626	0.374
E56 Other vitamin deficiencies	0.626	0.374
E51 Thiamine deficiency	0.626	0.374
E50 Vitamin A deficiency	0.626	0.374
E60 Dietary zinc deficiency	0.626	0.374
E59 Dietary selenium deficiency	0.626	0.374
E58 Dietary calcium deficiency	0.626	0.374
E54 Ascorbic acid deficiency	0.626	0.374
E52 Niacin deficiency [pellagra]	0.626	0.374
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.624	0.376
J69.0 Pneumonitis due to food and vomit	0.623	0.377
G24 Dystonia	0.623	0.377
A87.9 Viral meningitis, unspecified	0.623	0.377
M54.3 Sciatica	0.622	0.378
W22 Striking against or struck by other objects	0.622	0.378
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.622	0.378
S70.9 Superficial injury of hip and thigh, unspecified	0.622	0.378
B07 Viral warts	0.621	0.379
M47.2 Other spondylosis with radiculopathy	0.621	0.379
M14 Arthropathies in other diseases classified elsewhere	0.620	0.380
S10 Superficial injury of neck	0.620	0.380
T59.8 Other specified gases, fumes and vapours	0.620	0.380
M50.9 Cervical disk disorder, unspecified	0.619	0.380
M50.8 Other cervical disk disorders	0.619	0.380
G54 Nerve root and plexus disorders	0.620	0.380
T21 Burn and corrosion of trunk	0.619	0.381
M24.1 Other articular cartilage disorders	0.618	0.382
S67 Crushing injury of wrist and hand	0.618	0.382
S14 Injury of nerves and spinal cord at neck level	0.617	0.382
M66 Spontaneous rupture of synovium and tendon	0.617	0.383
X45 Accidental poisoning by and exposure to alcohol	0.617	0.383
M89.3 Hypertrophy of bone	0.617	0.383
E04 Other non-toxic goitre	0.617	0.383
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.617	0.383
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.616	0.384
B44.9 Aspergillosis, unspecified	0.616	0.384
S72.20 Subtrochanteric fracture (closed)	0.616	0.384
W94 Exposure to high and low air pressure and changes in air pressure	0.615	0.385
M12 Other specific arthropathies	0.615	0.385
M09 Juvenile arthritis in diseases classified elsewhere	0.615	0.385
M08 Juvenile arthritis	0.615	0.385
E87.0 Hyperosmolality and hypernatraemia	0.615	0.385
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.615	0.385

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations