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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10283576
log Bayes Factor = 19.8492
Chromosome 9   position 88,106,667  (GRCh37) Explore rs10283576 on Ensembl!
Variant rs10283576 is part of Cluster X0054

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
E10-E14 Diabetes mellitus
0.995 0.005 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.995 0.005 0.000
M05-M14 Inflammatory polyarthropathies
0.992 0.008 0.000
E11 Non-insulin-dependent diabetes mellitus
0.992 0.008 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.988 0.012 0.000
Chapter I Certain infectious and parasitic diseases
0.987 0.013 0.000
I60-I69 Cerebrovascular diseases
0.986 0.014 0.000
E11.9 Without complications
0.985 0.015 0.000
M70-M79 Other soft tissue disorders
0.982 0.018 0.000
I20-I25 Ischaemic heart diseases
0.978 0.022 0.000
I20 Angina pectoris
0.975 0.025 0.000
S00-S09 Injuries to the head
0.970 0.030 0.000
Y43 Primarily systemic agents
0.969 0.031 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.968 0.032 0.000
I20.0 Unstable angina
0.965 0.035 0.000
S80-S89 Injuries to the knee and lower leg
0.965 0.035 0.000
I44 Atrioventricular and left bundle-branch block
0.963 0.037 0.000
I51 Complications and ill-defined descriptions of heart disease
0.960 0.040 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.959 0.041 0.000
B95-B98 Bacterial, viral and other infectious agents
0.957 0.043 0.000
I50 Heart failure
0.955 0.045 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.955 0.045 0.000
N81 Female genital prolapse
0.953 0.047 0.000
W00-W19 Falls
0.947 0.053 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.943 0.057 0.000
Y43.3 Other antineoplastic drugs
0.943 0.057 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.939 0.061 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.939 0.061 0.000
M13 Other arthritis
0.938 0.062 0.000
I51.7 Cardiomegaly
0.938 0.062 0.000
M75 Shoulder lesions
0.933 0.067 0.000
N92 Excessive, frequent and irregular menstruation
0.930 0.070 0.000
N10-N16 Renal tubulo-interstitial diseases
0.927 0.073 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.927 0.073 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.927 0.073 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.922 0.078 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.922 0.078 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.918 0.082 0.000
Chapter VII Diseases of the eye and adnexa
0.917 0.083 0.000
N60-N64 Disorders of breast
0.910 0.090 0.000
S02 Fracture of skull and facial bones
0.910 0.090 0.000
I47 Paroxysmal tachycardia
0.909 0.091 0.000
B25-B34 Other viral diseases
0.907 0.093 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.906 0.094 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.906 0.094 0.000
I20.1 Angina pectoris with documented spasm
0.901 0.099 0.000
M13.9 Arthritis, unspecified
0.899 0.101 0.000
Z50 Care involving use of rehabilitation procedures
0.899 0.101 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.898 0.102 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.897 0.103 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.896 0.104 0.000
I44.0 Atrioventricular block, first degree
0.893 0.107 0.000
I50.9 Heart failure, unspecified
0.891 0.109 0.000
M75.4 Impingement syndrome of shoulder
0.891 0.109 0.000
I42 Cardiomyopathy
0.889 0.111 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.886 0.114 0.000
I65.2 Occlusion and stenosis of carotid artery
0.885 0.115 0.000
S50-S59 Injuries to the elbow and forearm
0.883 0.117 0.000
I69 Sequelae of cerebrovascular disease
0.880 0.120 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.877 0.123 0.000
M06 Other rheumatoid arthritis
0.874 0.126 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.873 0.127 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.872 0.128 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.870 0.130 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.870 0.130 0.000
N81.6 Rectocele
0.867 0.133 0.000
I44.1 Atrioventricular block, second degree
0.866 0.134 0.000
D50-D53 Nutritional anaemias
0.865 0.135 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.865 0.135 0.000
H53-H54 Visual disturbances and blindness
0.865 0.135 0.000
M10 Gout
0.865 0.135 0.000
E70-E90 Metabolic disorders
0.864 0.136 0.000
N17-N19 Renal failure
0.864 0.136 0.000
Z86 Personal history of certain other diseases
0.862 0.138 0.000
Chapter VIII Diseases of the ear and mastoid process
0.862 0.138 0.000
N00-N08 Glomerular diseases
0.861 0.139 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.860 0.140 0.000
I20.8 Other forms of angina pectoris
0.860 0.140 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.859 0.141 0.000
E11.3 With ophthalmic complications
0.858 0.142 0.000
Chapter V Mental and behavioural disorders
0.858 0.142 0.000
Z86.7 Personal history of diseases of the circulatory system
0.857 0.143 0.000
S82 Fracture of lower leg, including ankle
0.854 0.146 0.000
I67 Other cerebrovascular diseases
0.854 0.146 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.853 0.147 0.000
S00 Superficial injury of head
0.852 0.148 0.000
A30-A49 Other bacterial diseases
0.850 0.150 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.850 0.150 0.000
B34 Viral infection of unspecified site
0.849 0.151 0.000
Y40 Systemic antibiotics
0.848 0.152 0.000
D50 Iron deficiency anaemia
0.846 0.154 0.000
N80 Endometriosis
0.843 0.157 0.000
I46 Cardiac arrest
0.840 0.160 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.840 0.160 0.000
E50-E64 Other nutritional deficiencies
0.839 0.161 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.837 0.163 0.000
S81 Open wound of lower leg
0.829 0.171 0.000
I49 Other cardiac arrhythmias
0.829 0.171 0.000
M45-M49 Spondylopathies
0.829 0.171 0.000
I22 Subsequent myocardial infarction
0.828 0.172 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.825 0.175 0.000
Z45 Adjustment and management of implanted device
0.825 0.175 0.000
M11 Other crystal arthropathies
0.825 0.175 0.000
Y57 Other and unspecified drugs and medicaments
0.824 0.176 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.823 0.177 0.000
W19 Unspecified fall
0.821 0.179 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.820 0.180 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.820 0.180 0.000
Y52 Agents primarily affecting the cardiovascular system
0.818 0.182 0.000
W50-W64 Exposure to animate mechanical forces
0.818 0.182 0.000
R30-R39 Symptoms and signs involving the urinary system
0.815 0.185 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.812 0.187 0.000
M75.5 Bursitis of shoulder
0.811 0.189 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.810 0.189 0.000
N73 Other female pelvic inflammatory diseases
0.810 0.190 0.000
D50.9 Iron deficiency anaemia, unspecified
0.809 0.191 0.000
B34.9 Viral infection, unspecified
0.808 0.192 0.000
I05-I09 Chronic rheumatic heart diseases
0.808 0.192 0.000
E14 Unspecified diabetes mellitus
0.806 0.194 0.000
I31 Other diseases of pericardium
0.805 0.195 0.000
M50-M54 Other dorsopathies
0.805 0.195 0.000
I44.2 Atrioventricular block, complete
0.804 0.196 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.801 0.199 0.000
I47.1 Supraventricular tachycardia
0.801 0.199 0.000
H53 Visual disturbances
0.801 0.199 0.000
S70-S79 Injuries to the hip and thigh
0.800 0.199 0.000
N89 Other noninflammatory disorders of vagina
0.800 0.200 0.000
E10 Insulin-dependent diabetes mellitus
0.800 0.200 0.000
M79.8 Other specified soft tissue disorders
0.799 0.201 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.799 0.201 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.799 0.201 0.000
I42.0 Dilated cardiomyopathy
0.798 0.201 0.000
S06 Intracranial injury
0.795 0.205 0.000
N13 Obstructive and reflux uropathy
0.794 0.206 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.794 0.206 0.000
M75.3 Calcific tendinitis of shoulder
0.794 0.206 0.000
R87 Abnormal findings in specimens from female genital organs
0.792 0.208 0.000
N97 Female infertility
0.791 0.209 0.000
W10 Fall on and from stairs and steps
0.791 0.209 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.790 0.210 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.790 0.210 0.000
R94 Abnormal results of function studies
0.789 0.211 0.000
Z80 Family history of malignant neoplasm
0.788 0.212 0.000
M06.9 Rheumatoid arthritis, unspecified
0.785 0.215 0.000
N81.3 Complete uterovaginal prolapse
0.785 0.215 0.000
Z50.5 Speech therapy
0.784 0.216 0.000
Z60 Problems related to social environment
0.783 0.217 0.000
Y43.1 Antineoplastic antimetabolites
0.782 0.218 0.000
N02 Recurrent and persistent haematuria
0.782 0.218 0.000
R47-R49 Symptoms and signs involving speech and voice
0.782 0.218 0.000
E11.5 With peripheral circulatory complications
0.781 0.219 0.000
I63 Cerebral infarction
0.781 0.219 0.000
S02.1 Fracture of base of skull
0.780 0.220 0.000
N62 Hypertrophy of breast
0.780 0.220 0.000
W13 Fall from, out of or through building or structure
0.780 0.220 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.780 0.220 0.000
I50.1 Left ventricular failure
0.779 0.221 0.000
Y83.9 Surgical procedure, unspecified
0.779 0.221 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.777 0.223 0.000
N99-N99 Other disorders of the genitourinary system
0.776 0.223 0.000
T66-T78 Other and unspecified effects of external causes
0.776 0.224 0.000
M10.9 Gout, unspecified
0.773 0.227 0.000
Z97 Presence of other devices
0.773 0.227 0.000
N81.2 Incomplete uterovaginal prolapse
0.773 0.227 0.000
M80-M85 Disorders of bone density and structure
0.773 0.227 0.000
Z01.8 Other specified special examinations
0.771 0.229 0.000
R29.6 Tendency to fall, not elsewhere classified
0.769 0.231 0.000
Y44 Agents primarily affecting blood constituents
0.769 0.231 0.000
N19 Unspecified renal failure
0.768 0.232 0.000
M20-M25 Other joint disorders
0.768 0.232 0.000
R94.5 Abnormal results of liver function studies
0.766 0.234 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.765 0.235 0.000
Z95.4 Presence of other heart-valve replacement
0.764 0.235 0.000
Y83.4 Other reconstructive surgery
0.764 0.236 0.000
N92.3 Ovulation bleeding
0.763 0.237 0.000
N81.4 Uterovaginal prolapse, unspecified
0.762 0.238 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.761 0.239 0.000
V10-V19 Pedal cyclist injured in transport accident
0.761 0.239 0.000
Z49 Care involving dialysis
0.761 0.239 0.000
Z50.1 Other physical therapy
0.760 0.240 0.000
W20-W49 Exposure to inanimate mechanical forces
0.758 0.242 0.000
N81.1 Cystocele
0.758 0.242 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.757 0.243 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.756 0.244 0.000
I71 Aortic aneurysm and dissection
0.756 0.244 0.000
E83 Disorders of mineral metabolism
0.756 0.244 0.000
H90-H95 Other disorders of ear
0.755 0.245 0.000
R25 Abnormal involuntary movements
0.755 0.245 0.000
Z02 Examination and encounter for administrative purposes
0.753 0.247 0.000
Chapter XXII Codes for special purposes
0.752 0.248 0.000
I47.2 Ventricular tachycardia
0.752 0.248 0.000
H43-H45 Disorders of vitreous body and globe
0.752 0.248 0.000
I33 Acute and subacute endocarditis
0.752 0.248 0.000
E13 Other specified diabetes mellitus
0.751 0.249 0.000
I50.0 Congestive heart failure
0.750 0.250 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.748 0.252 0.000
Z45.2 Adjustment and management of vascular access device
0.748 0.252 0.000
S02.2 Fracture of nasal bones
0.748 0.252 0.000
N76 Other inflammation of vagina and vulva
0.748 0.252 0.000
N60 Benign mammary dysplasia
0.747 0.253 0.000
Z29 Need for other prophylactic measures
0.747 0.253 0.000
I67.9 Cerebrovascular disease, unspecified
0.746 0.254 0.000
N30-N39 Other diseases of urinary system
0.745 0.255 0.000
M05 Seropositive rheumatoid arthritis
0.745 0.255 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.744 0.256 0.000
M86-M90 Other osteopathies
0.744 0.256 0.000
S40-S49 Injuries to the shoulder and upper arm
0.743 0.257 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.742 0.258 0.000
Y40.0 Penicillins
0.742 0.258 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.742 0.258 0.000
Z41 Procedures for purposes other than remedying health state
0.741 0.258 0.000
M54 Dorsalgia
0.740 0.260 0.000
S52 Fracture of forearm
0.740 0.260 0.000
E11.2 With renal complications
0.739 0.260 0.000
M46 Other inflammatory spondylopathies
0.739 0.261 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.738 0.262 0.000
S90-S99 Injuries to the ankle and foot
0.737 0.263 0.000
M91-M94 Chondropathies
0.736 0.264 0.000
H65-H75 Diseases of middle ear and mastoid
0.736 0.264 0.000
S00.9 Superficial injury of head, part unspecified
0.736 0.264 0.000
M79.1 Myalgia
0.735 0.265 0.000
Z43 Attention to artificial openings
0.735 0.265 0.000
R87.6 Abnormal cytological findings
0.735 0.265 0.000
S02.0 Fracture of vault of skull
0.733 0.267 0.000
R26 Abnormalities of gait and mobility
0.733 0.267 0.000
Y83.5 Amputation of limb(s)
0.733 0.267 0.000
A49 Bacterial infection of unspecified site
0.732 0.267 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.732 0.268 0.000
Z50.2 Alcohol rehabilitation
0.732 0.268 0.000
N92.5 Other specified irregular menstruation
0.731 0.269 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.731 0.269 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.730 0.270 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.730 0.270 0.000
S00.0 Superficial injury of scalp
0.730 0.270 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.729 0.271 0.000
W08 Fall involving other furniture
0.729 0.271 0.000
I69.3 Sequelae of cerebral infarction
0.729 0.271 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.728 0.272 0.000
Z04 Examination and observation for other reasons
0.727 0.273 0.000
M77 Other enthesopathies
0.727 0.273 0.000
I62 Other nontraumatic intracranial haemorrhage
0.726 0.273 0.000
I67.2 Cerebral atherosclerosis
0.725 0.275 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.723 0.277 0.000
Z80.3 Family history of malignant neoplasm of breast
0.723 0.277 0.000
M79.5 Residual foreign body in soft tissue
0.723 0.277 0.000
N73.6 Female pelvic peritoneal adhesions
0.723 0.277 0.000
H54 Blindness and low vision
0.721 0.279 0.000
Z60.2 Living alone
0.719 0.281 0.000
N81.9 Female genital prolapse, unspecified
0.719 0.281 0.000
S80 Superficial injury of lower leg
0.719 0.281 0.000
Z13 Special screening examination for other diseases and disorders
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
N90.7 Vulvar cyst
0.716 0.284 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.716 0.284 0.000
S20-S29 Injuries to the thorax
0.715 0.284 0.000
E40-E46 Malnutrition
0.715 0.285 0.000
M25 Other joint disorders, not elsewhere classified
0.714 0.286 0.000
Z52 Donors of organs and tissues
0.714 0.286 0.000
E53 Deficiency of other B group vitamins
0.714 0.286 0.000
E12 Malnutrition-related diabetes mellitus
0.714 0.286 0.000
Y59 Other and unspecified vaccines and biological substances
0.713 0.287 0.000
Y58 Bacterial vaccines
0.713 0.287 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.713 0.287 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.713 0.287 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.713 0.287 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.713 0.287 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.713 0.287 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.713 0.287 0.000
Y48 Anaesthetics and therapeutic gases
0.713 0.287 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.713 0.287 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.713 0.287 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.713 0.287 0.000
N80.9 Endometriosis, unspecified
0.712 0.288 0.000
H53.0 Amblyopia ex anopsia
0.711 0.289 0.000
M10.99 Gout, unspecified (Site unspecified)
0.711 0.289 0.000
M14 Arthropathies in other diseases classified elsewhere
0.711 0.289 0.000
M12 Other specific arthropathies
0.711 0.289 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.711 0.289 0.000
M08 Juvenile arthritis
0.711 0.289 0.000
M07 Psoriatic and enteropathic arthropathies
0.711 0.289 0.000
E11.8 With unspecified complications
0.711 0.289 0.000
E11.7 With multiple complications
0.711 0.289 0.000
E11.6 With other specified complications
0.711 0.289 0.000
E11.1 With ketoacidosis
0.711 0.289 0.000
E11.0 With coma
0.711 0.289 0.000
S02.4 Fracture of malar and maxillary bones
0.711 0.289 0.000
T79-T79 Certain early complications of trauma
0.709 0.291 0.000
I74 Arterial embolism and thrombosis
0.709 0.291 0.000
N98 Complications associated with artificial fertilisation
0.708 0.292 0.000
N91 Absent, scanty and rare menstruation
0.708 0.292 0.000
N82 Fistulae involving female genital tract
0.708 0.292 0.000
N96 Habitual aborter
0.708 0.292 0.000
B99-B99 Other infectious diseases
0.708 0.292 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.708 0.292 0.000
B65-B83 Helminthiases
0.708 0.292 0.000
B50-B64 Protozoal diseases
0.708 0.292 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.708 0.292 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.708 0.292 0.000
A80-A89 Viral infections of the central nervous system
0.708 0.292 0.000
A75-A79 Rickettsioses
0.708 0.292 0.000
A70-A74 Other diseases caused by chlamydiae
0.708 0.292 0.000
A65-A69 Other spirochaetal diseases
0.708 0.292 0.000
A20-A28 Certain zoonotic bacterial diseases
0.708 0.292 0.000
A15-A19 Tuberculosis
0.708 0.292 0.000
Z40 Prophylactic surgery
0.708 0.292 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.707 0.293 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.707 0.293 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.707 0.293 0.000
Z98 Other postsurgical states
0.707 0.293 0.000
R20 Disturbances of skin sensation
0.706 0.294 0.000
V20-V29 Motorcycle rider injured in transport accident
0.706 0.294 0.000
M11.2 Other chondrocalcinosis
0.705 0.295 0.000
I49.9 Cardiac arrhythmia, unspecified
0.705 0.295 0.000
N86 Erosion and ectropion of cervix uteri
0.704 0.296 0.000
Z47 Other orthopaedic follow-up care
0.704 0.296 0.000
M76 Enthesopathies of lower limb, excluding foot
0.704 0.296 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.704 0.296 0.000
M71 Other bursopathies
0.704 0.296 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.704 0.296 0.000
S51 Open wound of forearm
0.703 0.297 0.000
Y45.0 Opioids and related analgesics
0.703 0.297 0.000
R33 Retention of urine
0.702 0.298 0.000
D50.8 Other iron deficiency anaemias
0.702 0.298 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.702 0.298 0.000
I23 Certain current complications following acute myocardial infarction
0.701 0.299 0.000
S89 Other and unspecified injuries of lower leg
0.701 0.299 0.000
F30-F39 Mood [affective] disorders
0.701 0.299 0.000
S82.6 Fracture of lateral malleolus
0.701 0.299 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.701 0.299 0.000
E83.1 Disorders of iron metabolism
0.700 0.300 0.000
M72 Fibroblastic disorders
0.699 0.301 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.699 0.301 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.698 0.302 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.697 0.302 0.000
H55-H59 Other disorders of eye and adnexa
0.697 0.303 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.696 0.304 0.000
S08 Traumatic amputation of part of head
0.696 0.304 0.000
S07 Crushing injury of head
0.696 0.304 0.000
S05 Injury of eye and orbit
0.696 0.304 0.000
S04 Injury of cranial nerves
0.696 0.304 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.696 0.304 0.000
Y43.9 Primarily systemic agent, unspecified
0.695 0.305 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.695 0.305 0.000
Y43.6 Enzymes, not elsewhere classified
0.695 0.305 0.000
Y43.5 Acidifying and alkalising agents
0.695 0.305 0.000
Y43.4 Immunosuppressive agents
0.695 0.305 0.000
Y43.2 Antineoplastic natural products
0.695 0.305 0.000
Y43.0 Antiallergic and antiemetic drugs
0.695 0.305 0.000
W19.1 Residential institution
0.695 0.305 0.000
N64 Other disorders of breast
0.695 0.305 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.694 0.306 0.000
B15-B19 Viral hepatitis
0.694 0.306 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.694 0.306 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.693 0.306 0.000
N63 Unspecified lump in breast
0.692 0.308 0.000
S88 Traumatic amputation of lower leg
0.692 0.308 0.000
S87 Crushing injury of lower leg
0.692 0.308 0.000
S86 Injury of muscle and tendon at lower leg level
0.692 0.308 0.000
S85 Injury of blood vessels at lower leg level
0.692 0.308 0.000
S84 Injury of nerves at lower leg level
0.692 0.308 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.691 0.309 0.000
I44.6 Other and unspecified fascicular block
0.691 0.309 0.000
I44.5 Left posterior fascicular block
0.691 0.309 0.000
I44.4 Left anterior fascicular block
0.691 0.309 0.000
I44.3 Other and unspecified atrioventricular block
0.691 0.309 0.000
R23 Other skin changes
0.690 0.310 0.000
N71 Inflammatory disease of uterus, except cervix
0.690 0.310 0.000
Z22 Carrier of infectious disease
0.690 0.310 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.690 0.310 0.000
R27 Other lack of coordination
0.689 0.311 0.000
W19.9 Unspecified place
0.689 0.311 0.000
I51.6 Cardiovascular disease, unspecified
0.688 0.312 0.000
I51.5 Myocardial degeneration
0.688 0.312 0.000
I51.4 Myocarditis, unspecified
0.688 0.312 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.688 0.312 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.688 0.312 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.688 0.312 0.000
I51.0 Cardiac septal defect, acquired
0.688 0.312 0.000
S01 Open wound of head
0.688 0.312 0.000
S02.10 Fracture of base of skull (closed)
0.688 0.312 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.687 0.313 0.000
M40-M43 Deforming dorsopathies
0.687 0.313 0.000
H18 Other disorders of cornea
0.685 0.315 0.000
N02.8 Other
0.684 0.316 0.000
N81.0 Female urethrocele
0.684 0.316 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.684 0.316 0.000
S82.1 Fracture of upper end of tibia
0.683 0.317 0.000
Q80-Q89 Other congenital malformations
0.683 0.317 0.000
X60-X84 Intentional self-harm
0.682 0.317 0.000
R39 Other symptoms and signs involving the urinary system
0.682 0.318 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.682 0.318 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.682 0.318 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.681 0.318 0.000
S81.8 Open wound of other parts of lower leg
0.680 0.320 0.000
W18 Other fall on same level
0.679 0.321 0.000
W17 Other fall from one level to another
0.679 0.321 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.679 0.321 0.000
W15 Fall from cliff
0.679 0.321 0.000
W14 Fall from tree
0.679 0.321 0.000
W12 Fall on and from scaffolding
0.679 0.321 0.000
W11 Fall on and from ladder
0.679 0.321 0.000
W09 Fall involving playground equipment
0.679 0.321 0.000
W07 Fall involving chair
0.679 0.321 0.000
W06 Fall involving bed
0.679 0.321 0.000
W05 Fall involving wheelchair
0.679 0.321 0.000
W04 Fall while being carried or supported by other persons
0.679 0.321 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.679 0.321 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.679 0.321 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.679 0.321 0.000
W00 Fall on same level involving ice and snow
0.679 0.321 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.679 0.321 0.000
I46.0 Cardiac arrest with successful resuscitation
0.679 0.321 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.678 0.321 0.000
I61 Intracerebral haemorrhage
0.678 0.322 0.000
S50 Superficial injury of forearm
0.678 0.322 0.000
E73 Lactose intolerance
0.678 0.322 0.000
N81.8 Other female genital prolapse
0.677 0.323 0.000
N92.4 Excessive bleeding in the premenopausal period
0.677 0.323 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.676 0.324 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.676 0.324 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.676 0.324 0.000
Chapter X Diseases of the respiratory system
0.676 0.324 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.675 0.324 0.000
H91 Other hearing loss
0.675 0.325 0.000
I51.8 Other ill-defined heart diseases
0.675 0.325 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.675 0.325 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.675 0.325 0.000
E65-E68 Obesity and other hyperalimentation
0.675 0.325 0.000
N90.5 Atrophy of vulva
0.674 0.326 0.000
N90.4 Leukoplakia of vulva
0.674 0.326 0.000
I31.3 Pericardial effusion (noninflammatory)
0.674 0.326 0.000
Z54 Convalescence
0.673 0.327 0.000
Z44 Fitting and adjustment of external prosthetic device
0.673 0.327 0.000
R29.4 Clicking hip
0.673 0.327 0.000
R29.3 Abnormal posture
0.673 0.327 0.000
R29.2 Abnormal reflex
0.673 0.327 0.000
R29.1 Meningismus
0.673 0.327 0.000
R29.0 Tetany
0.673 0.327 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.673 0.327 0.000
I46.9 Cardiac arrest, unspecified
0.673 0.327 0.000
M13.8 Other specified arthritis
0.672 0.327 0.000
M13.1 Monoarthritis, not elsewhere classified
0.672 0.327 0.000
M13.0 Polyarthritis, unspecified
0.672 0.327 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.671 0.329 0.000
N72 Inflammatory disease of cervix uteri
0.670 0.330 0.000
H16 Keratitis
0.670 0.330 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.670 0.330 0.000
E14.9 Without complications
0.670 0.330 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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